{"id":143786,"date":"2025-10-07T16:55:55","date_gmt":"2025-10-07T09:55:55","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=143786"},"modified":"2025-10-07T16:58:16","modified_gmt":"2025-10-07T09:58:16","slug":"rotacor-10mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/rotacor-10mg\/","title":{"rendered":"Rotacor 10mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong><a href=\"https:\/\/vnras.com\/drug\/rotacor-10mg\/\">Rotacor 10mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Lek Pharmaceuticals d.d., c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-19187-15.<\/strong><\/p>\n<h2>Rotacor 10mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean n\u00e9n bao phim<strong> Rotacor 10mg<\/strong> ch\u1ee9a:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t:<strong> Atorvastatin 10 mg <\/strong>(d\u01b0\u1edbi d\u1ea1ng Atorvastatin calci).<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c:\n<ul>\n<li>L\u00f5i vi\u00ean: Microcrystallin cellulose, lactose monohydrat, croscarmellose natri, hydroxypropyl cellulose, polysorbat 80, magie oxid, colloidal anhydrous silica, magie stearat.<\/li>\n<li>Bao phim: Hydroxypropylmethylcellulose, hydroxypropyl cellulose, titan dioxid (E 171), macrogol 6000, talc.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-19187-15<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean, H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Slovenia<\/p>\n<figure id=\"attachment_143792\" aria-describedby=\"caption-attachment-143792\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-143792\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Rotacor-10mg.jpg\" alt=\"Rotacor 10mg \u0111i\u1ec1u tr\u1ecb t\u0103ng cholesterol to\u00e0n ph\u1ea7n v\u00e0 LDL-cholesterol\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Rotacor-10mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Rotacor-10mg-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Rotacor-10mg-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Rotacor-10mg-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Rotacor-10mg-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-143792\" class=\"wp-caption-text\">Rotacor 10mg \u0111i\u1ec1u tr\u1ecb t\u0103ng cholesterol to\u00e0n ph\u1ea7n v\u00e0 LDL-cholesterol<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Rotacor 10mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Atorvastatin \u1ee9c ch\u1ebf men HMG-CoA reductase, m\u1ed9t enzym quan tr\u1ecdng trong qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t cholesterol t\u1ea1i gan. \u0110i\u1ec1u n\u00e0y l\u00e0m gi\u1ea3m l\u01b0\u1ee3ng cholesterol trong gan, k\u00edch th\u00edch gan t\u0103ng c\u01b0\u1eddng thu gi\u1eef LDL-cholesterol (&#8220;cholesterol x\u1ea5u&#8221;) t\u1eeb m\u00e1u.<\/p>\n<p>K\u1ebft qu\u1ea3 l\u00e0, Atorvastatin gi\u00fap:<\/p>\n<ul>\n<li>Gi\u1ea3m c\u00e1c th\u00e0nh ph\u1ea7n m\u1ee1 m\u00e1u c\u00f3 h\u1ea1i (cholesterol to\u00e0n ph\u1ea7n, LDL-C, triglycerid).<\/li>\n<li>T\u0103ng HDL-cholesterol (&#8220;cholesterol t\u1ed1t&#8221;).<\/li>\n<li>Mang l\u1ea1i c\u00e1c l\u1ee3i \u00edch tim m\u1ea1ch kh\u00e1c nh\u01b0 kh\u00e1ng vi\u00eam v\u00e0 \u1ed5n \u0111\u1ecbnh m\u1ea3ng x\u01a1 v\u1eefa.<\/li>\n<\/ul>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Sau khi u\u1ed1ng, Atorvastatin \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh, \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong 1-2 gi\u1edd nh\u01b0ng sinh kh\u1ea3 d\u1ee5ng to\u00e0n th\u00e2n ch\u1ec9 kho\u1ea3ng 14% do b\u1ecb gan chuy\u1ec3n h\u00f3a m\u1ea1nh l\u1ea7n \u0111\u1ea7u. Thu\u1ed1c li\u00ean k\u1ebft r\u1ea5t cao v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (&gt;98%), \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a t\u1ea1i gan b\u1edfi enzym CYP3A4 th\u00e0nh c\u00e1c ch\u1ea5t c\u00f3 ho\u1ea1t t\u00ednh v\u00e0 th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua m\u1eadt v\u1edbi th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 14 gi\u1edd.<\/p>\n<h2>Thu\u1ed1c Rotacor 10mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Rotacor 10mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh nh\u01b0 m\u1ed9t li\u1ec7u ph\u00e1p h\u1ed7 tr\u1ee3 cho ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb:<\/p>\n<ul>\n<li>T\u0103ng cholesterol m\u00e1u nguy\u00ean ph\u00e1t v\u00e0 r\u1ed1i lo\u1ea1n lipid m\u00e1u h\u1ed7n h\u1ee3p.<\/li>\n<li>T\u0103ng cholesterol m\u00e1u gia \u0111\u00ecnh d\u1ecb h\u1ee3p t\u1eed v\u00e0 \u0111\u1ed3ng h\u1ee3p t\u1eed.<\/li>\n<li>D\u1ef1 ph\u00f2ng c\u00e1c bi\u1ebfn c\u1ed1 tim m\u1ea1ch do x\u01a1 v\u1eefa: \u1ede nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 cao, Rotacor 10mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 nh\u1ed3i m\u00e1u c\u01a1 tim, \u0111\u1ed9t qu\u1ef5, v\u00e0 c\u00e1c th\u1ee7 thu\u1eadt t\u00e1i th\u00f4ng m\u1ea1ch v\u00e0nh.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c<\/h2>\n<h3>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c<\/h3>\n<p>Li\u1ec1u kh\u1edfi \u0111\u1ea7u th\u00f4ng th\u01b0\u1eddng l\u00e0 10 mg, 1 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>B\u00e1c s\u0129 c\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u sau m\u1ed7i 4 tu\u1ea7n ho\u1eb7c h\u01a1n t\u00f9y thu\u1ed9c v\u00e0o \u0111\u00e1p \u1ee9ng c\u1ee7a b\u1ec7nh nh\u00e2n v\u00e0 m\u1ee5c ti\u00eau \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c c\u00e1 th\u1ec3 h\u00f3a d\u1ef1a tr\u00ean m\u1ee9c cholesterol ban \u0111\u1ea7u v\u00e0 c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 \u0111i k\u00e8m.<\/p>\n<h3>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c<\/h3>\n<p>Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng, c\u00f3 th\u1ec3 u\u1ed1ng v\u00e0o b\u1ea5t k\u1ef3 th\u1eddi \u0111i\u1ec3m n\u00e0o trong ng\u00e0y, kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o b\u1eefa \u0103n.<\/p>\n<p>B\u1ec7nh nh\u00e2n ph\u1ea3i tu\u00e2n th\u1ee7 ch\u1ebf \u0111\u1ed9 \u0103n gi\u1ea3m cholesterol ti\u00eau chu\u1ea9n tr\u01b0\u1edbc v\u00e0 trong su\u1ed1t qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Rotacor 10mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>M\u1eabn c\u1ea3m v\u1edbi Atorvastatin ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>B\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh gan ti\u1ebfn tri\u1ec3n ho\u1eb7c c\u00f3 t\u00ecnh tr\u1ea1ng t\u0103ng transaminase huy\u1ebft thanh dai d\u1eb3ng kh\u00f4ng r\u00f5 nguy\u00ean nh\u00e2n, v\u01b0\u1ee3t qu\u00e1 3 l\u1ea7n gi\u1edbi h\u1ea1n tr\u00ean c\u1ee7a m\u1ee9c b\u00ecnh th\u01b0\u1eddng.<\/p>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai, \u0111ang cho con b\u00fa, ho\u1eb7c ph\u1ee5 n\u1eef trong \u0111\u1ed9 tu\u1ed5i sinh \u0111\u1ebb m\u00e0 kh\u00f4ng s\u1eed d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p tr\u00e1nh thai hi\u1ec7u qu\u1ea3.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Khuy\u1ebfn c\u00e1o th\u1ef1c hi\u1ec7n x\u00e9t nghi\u1ec7m men gan (transaminase) tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u00e0 \u0111\u1ecbnh k\u1ef3 sau \u0111\u00f3 theo ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129. C\u1ea7n ng\u01b0ng thu\u1ed1c n\u1ebfu men gan t\u0103ng cao dai d\u1eb3ng (h\u01a1n 3 l\u1ea7n gi\u1edbi h\u1ea1n tr\u00ean c\u1ee7a m\u1ee9c b\u00ecnh th\u01b0\u1eddng).<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p: Vi\u00eam m\u0169i h\u1ecdng, ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng, t\u0103ng \u0111\u01b0\u1eddng huy\u1ebft, \u0111au \u0111\u1ea7u, t\u00e1o b\u00f3n, \u0111\u1ea7y h\u01a1i, kh\u00f3 ti\u00eau, bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y, \u0111au c\u01a1, \u0111au kh\u1edbp, \u0111au l\u01b0ng.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Vi\u1ec7c s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi Rotacor 10mg v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf m\u1ea1nh enzym CYP3A4 c\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u0111\u00e1ng k\u1ec3 n\u1ed3ng \u0111\u1ed9 Atorvastatin trong m\u00e1u, d\u1eabn \u0111\u1ebfn t\u0103ng nguy c\u01a1 \u0111\u1ed9c t\u00ednh tr\u00ean c\u01a1. C\u1ea7n h\u1ebft s\u1ee9c th\u1eadn tr\u1ecdng khi ph\u1ed1i h\u1ee3p v\u1edbi:<\/p>\n<ul>\n<li>Kh\u00e1ng sinh macrolid (nh\u01b0 Clarithromycin).<\/li>\n<li>Thu\u1ed1c kh\u00e1ng n\u1ea5m nh\u00f3m azol (nh\u01b0 Itraconazole, Ketoconazole).<\/li>\n<li>C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf protease \u0111i\u1ec1u tr\u1ecb HIV (nh\u01b0 Ritonavir).<\/li>\n<li>M\u1ed9t l\u01b0\u1ee3ng l\u1edbn n\u01b0\u1edbc \u00e9p b\u01b0\u1edfi.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh tuy\u1ec7t \u0111\u1ed1i.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 \u1ea3nh h\u01b0\u1edfng kh\u00f4ng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Hi\u1ec7n kh\u00f4ng c\u00f3 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u1eb7c hi\u1ec7u cho qu\u00e1 li\u1ec1u Atorvastatin. Trong tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u, c\u1ea7n \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 \u00e1p d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 c\u1ea7n thi\u1ebft. Th\u1ea9m t\u00e1ch m\u00e1u kh\u00f4ng c\u00f3 hi\u1ec7u qu\u1ea3 do thu\u1ed1c g\u1eafn k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n thu\u1ed1c trong bao b\u00ec g\u1ed1c, \u1edf n\u01a1i kh\u00f4 r\u00e1o, nhi\u1ec7t \u0111\u1ed9 kh\u00f4ng qu\u00e1 30\u00b0C, v\u00e0 \u0111\u1ec3 xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Rotacor 10mg<\/h2>\n<p>Tr\u00ean th\u1ecb tr\u01b0\u1eddng c\u00f3 nhi\u1ec1u s\u1ea3n ph\u1ea9m ch\u1ee9a ho\u1ea1t ch\u1ea5t Atorvastatin 10mg, m\u1ed9t trong s\u1ed1 \u0111\u00f3 l\u00e0:<\/p>\n<ul>\n<li>T\u00ean s\u1ea3n ph\u1ea9m: Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/atorvastatin-10mg-tv-pharm\/\">Atorvastatin 10mg TV.Pharm<\/a><\/li>\n<li>Nh\u00e0 s\u1ea3n xu\u1ea5t: C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m TV.Pharm<\/li>\n<li>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/li>\n<li>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean n\u00e9n bao phim<\/li>\n<\/ul>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Luting Yu, Shixi Liu. Atorvastatin inhibits neuronal apoptosis via activating cAMP\/PKA\/p-CREB\/BDNF pathway in hypoxic-ischemic neonatal rats, truy c\u1eadp ng\u00e0y 07 th\u00e1ng 10 n\u0103m 2025 t\u1eeb<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35303316\/\" rel=\"noopener\"> https:\/\/pubmed.ncbi.nlm.nih.gov\/35303316\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>S\u1ea3n ph\u1ea9m thu\u1ed1c Rotacor 10mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Lek Pharmaceuticals d.d., c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-19187-15, nh\u01b0 m\u1ed9t li\u1ec7u ph\u00e1p h\u1ed7 tr\u1ee3 cho ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang.<\/p>\n","protected":false},"author":1,"featured_media":143787,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-143786","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/143786","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=143786"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/143787"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=143786"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=143786"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=143786"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}