{"id":143219,"date":"2025-10-07T15:20:24","date_gmt":"2025-10-07T08:20:24","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=143219"},"modified":"2025-10-22T05:39:41","modified_gmt":"2025-10-21T22:39:41","slug":"lopenca","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/lopenca\/","title":{"rendered":"Lopenca"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <\/strong><a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/lopenca\/\">Lopenca<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c H\u1eadu Giang, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-21139-14.<\/strong><\/p>\n<h2>Lopenca l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Thu\u1ed1c Lopenca DHG<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li >Paracetamol h\u00e0m l\u01b0\u1ee3ng 325mg<\/li>\n<li>Ibuprofen h\u00e0m l\u01b0\u1ee3ng 200mg<\/li>\n<li>Ph\u1ee5 li\u1ec7u v\u0111<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-21139-14<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 5 v\u1ec9 x 20 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9:  Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_143231\" aria-describedby=\"caption-attachment-143231\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-143231\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/lopenca.jpg\" alt=\"Lopenca\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/lopenca.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/lopenca-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/lopenca-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/lopenca-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/lopenca-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-143231\" class=\"wp-caption-text\">Lopenca gi\u00fap gi\u1ea3m \u0111au, h\u1ea1 s\u1ed1t<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Lopenca<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p >Paracetamol t\u00e1c \u0111\u1ed9ng l\u00ean trung t\u00e2m \u0111i\u1ec1u nhi\u1ec7t v\u00f9ng d\u01b0\u1edbi \u0111\u1ed3i gi\u00fap h\u1ea1 nhi\u1ec7t \u0111\u1ed9 \u1edf ng\u01b0\u1eddi \u0111ang s\u1ed1t, hi\u1ebfm khi l\u00e0m h\u1ea1 nhi\u1ec7t \u1edf ng\u01b0\u1eddi b\u00ecnh th\u01b0\u1eddng, m\u1eb7c kh\u00e1c c\u00f2n n\u00e2ng ng\u01b0\u1ee1ng ch\u1ecbu \u0111au gi\u00fap gi\u1ea3m \u0111au.<\/p>\n<p>Ibuprofen \u1ee9c ch\u1ebf enzym prostaglandin synthetase, ng\u0103n ng\u1eeba t\u1ea1o prostaglandin gi\u00fap gi\u1ea3m vi\u00eam, gi\u1ea3m \u0111au, h\u1ea1 s\u1ed1t.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p >Paracetamol: Thu\u1ed1c h\u1ea5p thu nhanh qua ti\u00eau h\u00f3a sau khi u\u1ed1ng, n\u00f3 \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a \u1edf gan, th\u1ea3i qua th\u1eadn. Th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 1,25\u20133 gi\u1edd<\/p>\n<p>Ibuprofen: Thu\u1ed1c h\u1ea5p thu t\u1ed1t, \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh sau 1\u20132 gi\u1edd, thu\u1ed1c \u0111\u01b0\u1ee3c th\u1ea3i ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u. Th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 2 gi\u1edd.<\/p>\n<h2>Thu\u1ed1c Lopenca tr\u1ecb b\u1ec7nh g\u00ec?<\/h2>\n<p >Thu\u1ed1c Lopenca \u0111\u01b0\u1ee3c d\u00f9ng trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n<p >\u0110au c\u01a1, \u0111au kh\u1edbp, bong g\u00e2n, tr\u1eadt kh\u1edbp, \u0111au do ch\u1ea5n th\u01b0\u01a1ng.<\/p>\n<p>Vi\u00eam th\u1ea7n kinh (\u0111au l\u01b0ng, v\u1eb9o c\u1ed5,&#8230;).<\/p>\n<p>\u0110au r\u0103ng, nh\u1ee9c \u0111\u1ea7u, c\u1ea3m s\u1ed1t, \u0111au b\u1ee5ng kinh, \u0111au sau ph\u1eabu thu\u1eadt.<\/p>\n<h2>Li\u1ec1u d\u00f9ng-C\u00e1ch d\u00f9ng Lopenca<\/h2>\n<h3>Li\u1ec1u d\u00f9ng Lopenca<\/h3>\n<p>T\u00f9y theo tr\u01b0\u1eddng h\u1ee3p m\u00e0 \u0111\u01b0\u1ee3c b\u00e1c s\u0129 ch\u1ec9 \u0111\u1ecbnh li\u1ec1u d\u00f9ng kh\u00e1c nhau, d\u01b0\u1edbi \u0111\u00e2y l\u00e0 li\u1ec1u d\u00f9ng tham kh\u1ea3o.<\/p>\n<p >Ng\u01b0\u1eddi l\u1edbn: n\u00ean u\u1ed1ng 1\u20132 vi\u00ean v\u00e0 u\u1ed1ng 2\u20133 l\u1ea7n\/ng\u00e0y.<\/p>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p>D\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng, n\u00ean u\u1ed1ng sau b\u1eefa \u0103n \u0111\u1ec3 tr\u00e1nh k\u00edch \u1ee9ng d\u1ea1 d\u00e0y.<\/p>\n<p>N\u00ean u\u1ed1ng nguy\u00ean vi\u00ean, kh\u00f4ng t\u1ef1 \u00fd b\u1ebb nghi\u1ec1n vi\u00ean thu\u1ed1c.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Lopenca trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c <strong>Lopenca H\u1eadu Giang<\/strong> trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n<ul>\n<li >D\u1ecb \u1ee9ng v\u1edbi paracetamol, ibuprofen ho\u1eb7c c\u00e1c NSAIDs.<\/li>\n<li>Lo\u00e9t d\u1ea1 d\u00e0y \u2013 t\u00e1 tr\u00e0ng ti\u1ebfn tri\u1ec3n.<\/li>\n<li>Hen ph\u1ebf qu\u1ea3n, co th\u1eaft ph\u1ebf qu\u1ea3n, b\u1ec7nh tim m\u1ea1ch, r\u1ed1i lo\u1ea1n ch\u1ea3y m\u00e1u.<\/li>\n<li>Suy gan, suy th\u1eadn n\u1eb7ng.<\/li>\n<li>Ph\u1ee5 n\u1eef mang thai 3 th\u00e1ng cu\u1ed1i.<\/li>\n<li>Suy tim sung huy\u1ebft, \u0111ang d\u00f9ng thu\u1ed1c l\u1ee3i ti\u1ec3u m\u00e0 gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li >Th\u1eadn tr\u1ecdng khi d\u00f9ng thu\u1ed1c cho ng\u01b0\u1eddi b\u1ecb suy gan, suy th\u1eadn, nghi\u1ec7n r\u01b0\u1ee3u.<\/li>\n<li>Th\u1eadn tr\u1ecdng khi d\u00f9ng thu\u1ed1c cho ng\u01b0\u1eddi cao tu\u1ed5i.<\/li>\n<li>Kh\u00f4ng n\u00ean u\u1ed1ng r\u01b0\u1ee3u khi d\u00f9ng thu\u1ed1c v\u00ec d\u1ec5 l\u00e0m t\u0103ng \u0111\u1ed9c t\u00ednh tr\u00ean gan.<\/li>\n<li>C\u1ea3nh b\u00e1o v\u1ec1 c\u00e1c ph\u1ea3n \u1ee9ng ph\u00e1t ban n\u1eb7ng: SJS, TEN, Lyell, AGEP.<\/li>\n<li>\u0110\u1ecdc k\u1ef9 h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng tr\u01b0\u1edbc khi d\u00f9ng thu\u1ed1c.<\/li>\n<li>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c khi xu\u1ea5t hi\u1ec7n c\u00e1c d\u1ea5u hi\u1ec7u h\u01b0 h\u1ecfng nh\u01b0 \u1ea9m m\u1ed1c, ch\u1ea3y n\u01b0\u1edbc, bi\u1ebfn \u0111\u1ed5i m\u00e0u, m\u00f9i v\u1ecb b\u1ea5t th\u01b0\u1eddng.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5 Lopenca<\/h3>\n<p >Sau khi d\u00f9ng thu\u1ed1c Lopenca c\u00f3 th\u1ec3 g\u1eb7p m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p:<\/p>\n<ul>\n<li>Bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, kh\u00f3 ti\u00eau, \u0111\u1ea7y h\u01a1i.<\/li>\n<li>Nh\u1ee9c \u0111\u1ea7u, ch\u00f3ng m\u1eb7t.<\/li>\n<li>Xu\u1ea5t huy\u1ebft ti\u00eau h\u00f3a (hi\u1ebfm nh\u01b0ng nguy hi\u1ec3m).<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p >Kh\u00f4ng d\u00f9ng thu\u1ed1c cho ph\u1ee5 n\u1eef mai thai, \u0111\u1eb7c bi\u1ec7t trong 3 th\u00e1ng cu\u1ed1i thai k\u1ef3.<\/p>\n<p >Paracetamol v\u00e0 ibuprofen v\u00e0o s\u1eefa r\u1ea5t \u00edt, c\u00f3 th\u1ec3 d\u00f9ng n\u1ebfu li\u1ec1u m\u1eb9 d\u00f9ng b\u00ecnh th\u01b0\u1eddng.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p >Th\u1eadn tr\u1ecdng khi d\u00f9ng thu\u1ed1c cho ng\u01b0\u1eddi l\u00e1i xe, v\u1eadn h\u00e0nh m\u00e1y m\u00f3c do c\u00f3 th\u1ec3 g\u00e2y ch\u00f3ng m\u1eb7t.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p >Paracetamol: G\u00e2y ng\u1ed9 \u0111\u1ed9c gan, c\u00f3 th\u1ec3 t\u1eed vong n\u1ebfu d\u00f9ng li\u1ec1u cao k\u00e9o d\u00e0i (\u22657,5g\/ng\u00e0y) v\u1edbi c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, v\u00e0ng da, xanh t\u00edm. X\u1eed tr\u00ed b\u1eb1ng c\u00e1ch r\u1eeda d\u1ea1 d\u00e0y (trong 4 gi\u1edd \u0111\u1ea7u). D\u00f9ng N-acetylcystein c\u00e0ng s\u1edbm c\u00e0ng t\u1ed1t, hi\u1ec7u qu\u1ea3 cao nh\u1ea5t trong v\u00f2ng 10 gi\u1edd. C\u00f3 th\u1ec3 d\u00f9ng th\u00eam methionin, than ho\u1ea1t.<\/p>\n<p >Ibuprofen: tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u bao g\u1ed3m \u0111au b\u1ee5ng, bu\u1ed3n n\u00f4n, ch\u00f3ng m\u1eb7t, toan chuy\u1ec3n h\u00f3a. X\u1eed tr\u00ed b\u1eb1ng c\u00e1ch r\u1eeda d\u1ea1 d\u00e0y, g\u00e2y n\u00f4n, u\u1ed1ng than ho\u1ea1t, truy\u1ec1n d\u1ecbch ki\u1ec1m \u0111\u1ec3 l\u1ee3i ti\u1ec3u. M\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng c\u00f3 th\u1ec3 d\u00f9ng ph\u01b0\u01a1ng ph\u00e1p th\u1ea9m t\u00e1ch m\u00e1u.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h3>\n<p >Li\u00ean quan \u0111\u1ebfn Paracetamol:<\/p>\n<ul>\n<li>T\u0103ng t\u00e1c d\u1ee5ng thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng (nh\u01b0 warfarin).<\/li>\n<li>D\u1ec5 g\u00e2y h\u1ea1 s\u1ed1t qu\u00e1 m\u1ee9c n\u1ebfu d\u00f9ng v\u1edbi phenothiazin.<\/li>\n<li>Nguy c\u01a1 \u0111\u1ed9c gan khi d\u00f9ng chung v\u1edbi thu\u1ed1c ch\u1ed1ng co gi\u1eadt (phenytoin, carbamazepin\u2026), Isoniazid (thu\u1ed1c lao).<\/li>\n<\/ul>\n<p>Li\u00ean quan \u0111\u1ebfn Ibuprofen:<\/p>\n<ul>\n<li>L\u00e0m t\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a: methotrexat, digoxin.<\/li>\n<li>T\u0103ng t\u00e1c d\u1ee5ng ph\u1ee5 khi d\u00f9ng c\u00f9ng NSAIDs kh\u00e1c (nguy c\u01a1 ch\u1ea3y m\u00e1u, lo\u00e9t, kh\u00e1ng sinh quinolon (nguy c\u01a1 co gi\u1eadt), c\u00f3 th\u1ec3 l\u00e0m k\u00e9o d\u00e0i th\u1eddi gian ch\u1ea3y m\u00e1u do \u1ee9c ch\u1ebf k\u1ebft t\u1ee5 ti\u1ec3u c\u1ea7u.<\/li>\n<\/ul>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p >N\u01a1i kh\u00f4 r\u00e1o, nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng, tr\u00e1nh \u00e1nh s\u00e1ng.<\/p>\n<p>Tr\u00e1nh n\u01a1i \u1ea9m nh\u01b0 nh\u00e0 t\u1eafm, kh\u00f4ng \u0111\u1ec3 ng\u0103n \u0111\u00e1.<\/p>\n<p>\u0110\u1ec3 xa t\u1ea7m tay tr\u1ebb em v\u00e0 th\u00fa nu\u00f4i.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Lopenca nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/pabemin-325\/\" data-mil=\"140572\">Pabemin 325<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m C\u1eedu Long, gi\u00fap gi\u1ea3m \u0111au, h\u1ea1 s\u1ed1t.<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/hapacol-325\/\" data-mil=\"140572\">Hapacol 325<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH MTV D\u01b0\u1ee3c ph\u1ea9m DHG, c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m \u0111au v\u00e0 h\u1ea1 s\u1ed1t.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Paracetamol and ibuprofen combination for the management of acute mild-to-moderate pain in children: expert consensus using the Nominal Group Technique (NGT), truy c\u1eadp ng\u00e0y 07 th\u00e1ng 10 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10031994\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10031994\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Lopenca \u0111\u01b0\u1ee3c d\u00f9ng trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p sau \u0111au c\u01a1, \u0111au kh\u1edbp, bong g\u00e2n, tr\u1eadt kh\u1edbp, \u0111au do ch\u1ea5n th\u01b0\u01a1ng, vi\u00eam th\u1ea7n kinh, \u0111au r\u0103ng, nh\u1ee9c \u0111\u1ea7u, c\u1ea3m s\u1ed1t, \u0111au b\u1ee5ng kinh, \u0111au sau ph\u1eabu thu\u1eadt.<\/p>\n","protected":false},"author":1,"featured_media":143237,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-143219","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/143219","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=143219"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/143237"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=143219"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=143219"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=143219"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}