{"id":142837,"date":"2025-10-06T08:22:18","date_gmt":"2025-10-06T01:22:18","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=142837"},"modified":"2025-10-06T08:25:33","modified_gmt":"2025-10-06T01:25:33","slug":"aginalxic","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/aginalxic\/","title":{"rendered":"Aginalxic"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <\/strong><a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/aginalxic\/\">Aginalxic<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Chi nh\u00e1nh c\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Agimexpharm- Nh\u00e0 m\u00e1y s\u1ea3n xu\u1ea5t d\u01b0\u1ee3c ph\u1ea9m Agimexpharm, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-23486-15<\/strong><\/p>\n<h2>Aginalxic l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Thu\u1ed1c Aginalxic<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n: Acid nalidixic 500mg<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-23486-15<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Aginalxic<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Acid nalidixic thu\u1ed9c nh\u00f3m kh\u00e1ng sinh quinolone, c\u00f3 ph\u1ed5 t\u00e1c d\u1ee5ng r\u1ed9ng tr\u00ean h\u1ea7u h\u1ebft c\u00e1c vi khu\u1ea9n \u01b0a khi gam \u00e2m, th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u.<\/p>\n<p>C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a Acid nalidixic: Ho\u1ea1t ch\u1ea5t \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh sao ch\u00e9p DNA nh\u1edd \u1ee9c ch\u1ebf ho\u1ea1t t\u00ednh DNA gyrase<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Acid nalidixic h\u1ea5p thu nhanh ch\u00f3ng v\u00e0 g\u1ea7n nh\u01b0 ho\u00e0n to\u00e0n khi s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh kho\u1ea3ng 20-50 mcg\/ml, \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 2 gi\u1edd s\u1eed d\u1ee5ng. T \u00bd huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 1 \u0111\u1ebfn 2,5 gi\u1edd.<\/p>\n<p>Ph\u00e2n b\u1ed1: T\u1ef7 l\u1ec7 thu\u1ed1c li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 93% (Acid nalidixic) v\u00e0 63% (acid hydroxy nalidixic)<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Acid nalidixic chuy\u1ec3n h\u00f3a t\u1ea1o th\u00e0nh acid hydroxy nalidixic, c\u00f3 ho\u1ea1t t\u00ednh d\u01b0\u1ee3c l\u00fd.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Ho\u1ea1t ch\u1ea5t v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u, m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf 4% li\u1ec1u \u0111\u00e0o th\u1ea3i qua ph\u00e2n.<\/p>\n<h2>Thu\u1ed1c Aginalxic \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c <strong>Aginalxic<\/strong> ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u d\u01b0\u1edbi ch\u01b0a bi\u1ebfn ch\u1ee9ng.<\/p>\n<figure id=\"attachment_143495\" aria-describedby=\"caption-attachment-143495\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-143495\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Aginalxic.jpg\" alt=\"Aginalxic \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u ch\u01b0a bi\u1ebfn ch\u1ee9ng\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Aginalxic.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Aginalxic-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Aginalxic-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Aginalxic-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/Aginalxic-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-143495\" class=\"wp-caption-text\">Aginalxic \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u ch\u01b0a bi\u1ebfn ch\u1ee9ng<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Aginalxic<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<ul>\n<li>Li\u1ec1u d\u00f9ng cho tr\u1ebb em 3 th\u00e1ng tu\u1ed5i \u0111\u1ebfn 12 tu\u1ed5i: 50-55 mg\/kg\/ng\u00e0y, chia l\u00e0m 4 l\u1ea7n trong ng\u00e0y. Khi s\u1eed d\u1ee5ng th\u1eddi gian d\u00e0i, d\u00f9ng li\u1ec1u 30-33 mg\/kg\/ng\u00e0y<\/li>\n<li>Li\u1ec1u d\u00f9ng cho ng\u01b0\u1eddi l\u1edbn: 2 vi\u00ean\/l\u1ea7n x 4 l\u1ea7n\/ng\u00e0y, s\u1eed d\u1ee5ng 7-14 ng\u00e0y<\/li>\n<li>Li\u1ec1u d\u00f9ng cho b\u1ec7nh nh\u00e2n suy th\u1eadn:<\/li>\n<\/ul>\n<table>\n<tbody>\n<tr>\n<td width=\"312\">\u0110\u1ed9 thanh th\u1ea3i creatinine (ml\/ph\u00fat)<\/td>\n<td width=\"312\">Li\u1ec1u d\u00f9ng<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">&gt; 20<\/td>\n<td width=\"312\">D\u00f9ng li\u1ec1u b\u00ecnh th\u01b0\u1eddng<\/td>\n<\/tr>\n<tr>\n<td width=\"312\">&lt; 20<\/td>\n<td width=\"312\">\u00bd li\u1ec1u b\u00ecnh th\u01b0\u1eddng<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p>Thu\u1ed1c Aginalxic d\u1ea1ng vi\u00ean n\u00e9n bao phim, s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng, n\u00ean d\u00f9ng thu\u1ed1c l\u00fac \u0111\u00f3i.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Aginalxic trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng Aginalxic cho b\u1ec7nh nh\u00e2n m\u1eabn c\u1ea3m v\u1edbi acid nalidixic ho\u1eb7c kh\u00e1ng sinh quinolone, ho\u1eb7c b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c n\u00e0o trong thu\u1ed1c<\/li>\n<li>Kh\u00f4ng d\u00f9ng thu\u1ed1c cho tr\u1ebb nh\u1ecf d\u01b0\u1edbi 3 th\u00e1ng tu\u1ed5i, ph\u1ee5 n\u1eef \u0111ang mang thai<\/li>\n<li>Kh\u00f4ng s\u1eed d\u1ee5ng cho b\u1ec7nh nh\u00e2n suy th\u1eadn, r\u1ed1i lo\u1ea1n t\u1ea1o m\u00e1u, \u0111\u1ed9ng kinh, t\u0103ng \u00e1p l\u1ef1c n\u1ed9i s\u1ecd<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Aginalxic<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Th\u1eadn tr\u1ecdng khi d\u00f9ng Aginalxic cho b\u1ec7nh nh\u00e2n gi\u1ea3m ch\u1ee9c n\u0103ng gan th\u1eadn, thi\u1ebfu h\u1ee5t enzyme G6PD do t\u0103ng nguy c\u01a1 t\u00edch l\u0169y thu\u1ed1c<\/li>\n<li>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y tho\u00e1i h\u00f3a kh\u1edbp \u1edf \u0111\u1ed1i t\u01b0\u1ee3ng ch\u01b0a tr\u01b0\u1edfng th\u00e0nh, do \u0111\u00f3 kh\u00f4ng d\u00f9ng cho tr\u1ebb d\u01b0\u1edbi 3 th\u00e1ng tu\u1ed5i<\/li>\n<li>Kh\u00f4ng d\u00f9ng Aginalxic khi h\u1ebft h\u1ea1n s\u1eed d\u1ee5ng<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>Th\u01b0\u1eddng g\u1eb7p: nh\u1ee9c \u0111\u1ea7u, ti\u00eau ch\u1ea3y, bu\u1ed3n n\u00f4n, n\u00f4n, nh\u00ecn m\u1edd, m\u1ee5n n\u01b0\u1edbc<\/li>\n<li>\u00cdt g\u1eb7p: t\u0103ng \u00e1p l\u1ef1c n\u1ed9i s\u1ecd, ng\u1ee9a, m\u1ec1 \u0111ay, c\u1ea3n quang<\/li>\n<li>Hi\u1ebfm g\u1eb7p: l\u00fa l\u1eabn, \u1ea3o gi\u00e1c, \u00e1c m\u1ed9ng, ph\u1ea3n v\u1ec7, gi\u1ea3m ti\u1ec3u c\u1ea7u b\u1ea1ch c\u1ea7u, ph\u00f9 m\u1ea1ch, \u0111au kh\u1edbp<\/li>\n<li>C\u1ea7n th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 v\u1ec1 c\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i g\u1eb7p ph\u1ea3i trong su\u1ed1t giai \u0111o\u1ea1n \u0111i\u1ec1u tr\u1ecb v\u1edbi thu\u1ed1c<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Aginalxic + theophylin l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 theophylin trong huy\u1ebft t\u01b0\u01a1ng, t\u0103ng \u0111\u1ed9c t\u00ednh thu\u1ed1c<\/li>\n<li>Aginalxic + cafein l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 cafein<\/li>\n<li>T\u0103ng t\u00e1c d\u1ee5ng c\u1ee7a warfarin khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi<\/li>\n<li>T\u0103ng n\u1ed3ng \u0111\u1ed9 cycloprorin trong huy\u1ebft t\u01b0\u01a1ng<\/li>\n<li>C\u00e1c thu\u1ed1c kh\u00e1ng acid l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 Aginalxic trong n\u01b0\u1edbc ti\u1ec3u<\/li>\n<li>Nitrofuratoin l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u1ee7a Aginalxic<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<ul>\n<li>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng Aginalxic cho ph\u1ee5 n\u1eef c\u00f3 thai<\/li>\n<li>Thu\u1ed1c Aginalxic c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi \u0111ang nu\u00f4i con b\u1eb1ng s\u1eefa m\u1eb9\/<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c Aginalxic g\u00e2y nh\u1ee9c \u0111\u1ea7u, \u1ea3o gi\u00e1c, co gi\u1eadt, th\u1eadn tr\u1ecdng khi d\u00f9ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u Aginalxic: co gi\u1eadt, t\u0103ng \u00e1p l\u1ef1c n\u1ed9i s\u1ecd, bu\u1ed3n n\u00f4n, n\u00f4n, toan chuy\u1ec3n h\u00f3a, ng\u1ee7 l\u1ecbm<\/p>\n<p>X\u1eed tr\u00ed: r\u1eeda d\u1ea1 d\u00e0y, truy\u1ec1n d\u1ecbch, \u00e1p d\u1ee5ng bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Khuy\u1ebfn kh\u00edch b\u1ea3o qu\u1ea3n Aginalxic \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t, nhi\u1ec7t \u0111\u1ed9 kh\u00f4ng qu\u00e1 30 \u0111\u1ed9 C, kh\u00f4ng ti\u1ebfp x\u00fac tr\u1ef1c ti\u1ebfp v\u1edbi \u00e1nh s\u00e1ng c\u01b0\u1eddng \u0111\u1ed9 cao. N\u00ean \u0111\u1ec3 s\u1ea3n ph\u1ea9m c\u00e1ch xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Aginalxic nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/quinoneg\/\">Quinoneg<\/a> v\u1edbi th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Acid nalidixic 500mg, s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Flamingo Pharm., Ltd \u2013 \u1ea4N \u0110\u1ed8, \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Aginalxic do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i file<a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/10\/HDSD-Aginalxic-vnras.pdf\"> t\u1ea1i \u0111\u00e2y<\/a><\/li>\n<li>Harrison LH, Cox CE. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/5532919\/\" rel=\"noopener\">Bacteriologic and pharmacodynamic aspects of nalidixic acid<\/a>, truy c\u1eadp ng\u00e0y 06 th\u00e1ng 10 n\u0103m 2025<\/li>\n<li>Vree TB, Wijnands WJ, Baars AM, Hekster YA. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/3205675\/\" rel=\"noopener\">Pharmacokinetics of nalidixic acid in man: hydroxylation and glucuronidation. Pharm Weekbl Sci<\/a>, truy c\u1eadp ng\u00e0y 06 th\u00e1ng 10 n\u0103m 2025<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Aginalxic ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u d\u01b0\u1edbi ch\u01b0a bi\u1ebfn ch\u1ee9ng, s\u1ea3n xu\u1ea5t b\u1edfi Chi nh\u00e1nh c\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Agimexpharm- Nh\u00e0 m\u00e1y s\u1ea3n xu\u1ea5t d\u01b0\u1ee3c ph\u1ea9m Agimexpharm<\/p>\n","protected":false},"author":1,"featured_media":143497,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-142837","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/142837","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=142837"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/143497"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=142837"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=142837"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=142837"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}