{"id":142437,"date":"2025-09-29T16:07:41","date_gmt":"2025-09-29T09:07:41","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=142437"},"modified":"2025-09-29T17:07:29","modified_gmt":"2025-09-29T10:07:29","slug":"methorfar-15","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/methorfar-15\/","title":{"rendered":"Methorfar 15"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Methorfar 15 c\u00f3 c\u01a1 s\u1edf s\u1ea3n xu\u1ea5t l\u00e0 C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m d\u01b0\u1ee3c li\u1ec7u Pharmedic, \u0111\u01b0\u1ee3c l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam v\u1edbi s\u1ed1 \u0111\u0103ng k\u00fd l\u00e0 VD-11551-10.<\/strong><\/p>\n<h2>Methorfar 15 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean<strong> Methorfar 15<\/strong>\u00a0ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li>Dextromethorphan hydrobromid 15mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf : Vi\u00ean n\u00e9n<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-11551-10<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<h2>Methorfar 15 c\u00f3 t\u00e1c d\u1ee5ng g\u00ec?<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Dextromethorphan hydrobromid \u1ee9c ch\u1ebf trung t\u00e2m ho \u1edf h\u00e0nh n\u00e3o b\u1eb1ng c\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng l\u00ean th\u1ee5 th\u1ec3 NMDA v\u00e0 th\u1ee5 th\u1ec3 sigma, c\u0169ng nh\u01b0 \u1ea3nh h\u01b0\u1edfng t\u1edbi t\u00e1i h\u1ea5p thu serotonin, do \u0111\u00f3 l\u00e0m t\u0103ng ng\u01b0\u1ee1ng ho. Thu\u1ed1c c\u00f3 c\u1ea5u tr\u00fac li\u00ean quan \u0111\u1ebfn morphin nh\u01b0ng kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m \u0111au \u0111\u00e1ng k\u1ec3 v\u00e0 \u00edt g\u00e2y an th\u1ea7n.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu : H\u1ea5p thu nhanh qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, t\u00e1c d\u1ee5ng gi\u1ea3m ho xu\u1ea5t hi\u1ec7n trong v\u00f2ng 15 \u0111\u1ebfn 30 ph\u00fat sau khi u\u1ed1ng.<\/p>\n<p>Ph\u00e2n b\u1ed1 : Thu\u1ed1c v\u00e0o tu\u1ea7n ho\u00e0n chung v\u00e0 th\u00e2m nh\u1eadp h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng \u0111\u1ec3 t\u00e1c \u0111\u1ed9ng l\u00ean trung t\u00e2m ho.<\/p>\n<p>Chuy\u1ec3n h\u00f3a : Chuy\u1ec3n h\u00f3a m\u1ea1nh \u1edf gan, ch\u1ee7 y\u1ebfu b\u1edfi enzym CYP2D6 th\u00e0nh dextrorphan l\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh. Ki\u1ec3u h\u00ecnh di truy\u1ec1n CYP2D6 v\u00e0 thu\u1ed1c \u1ee9c ch\u1ebf CYP2D6 \u1ea3nh h\u01b0\u1edfng l\u1edbn \u0111\u1ebfn t\u1ed1c \u0111\u1ed9 chuy\u1ec3n h\u00f3a v\u00e0 n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00e1u.<\/p>\n<p>Th\u1ea3i tr\u1eeb : Thu\u1ed1c g\u1ed1c v\u00e0 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a \u0111\u01b0\u1ee3c th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u. Th\u1eddi gian b\u00e1n th\u1ea3i ng\u1eafn \u1edf ng\u01b0\u1eddi chuy\u1ec3n h\u00f3a nhanh v\u00e0 k\u00e9o d\u00e0i \u1edf ng\u01b0\u1eddi chuy\u1ec3n h\u00f3a k\u00e9m ho\u1eb7c khi c\u00f3 \u1ee9c ch\u1ebf CYP2D6.<\/p>\n<h2>Methorfar 15 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p><strong>Methorfar 15 Dextromethorphan <\/strong>\u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh :<\/p>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng ho khan do h\u1ecdng v\u00e0 ph\u1ebf qu\u1ea3n b\u1ecb k\u00edch th\u00edch trong c\u1ea3m l\u1ea1nh th\u00f4ng th\u01b0\u1eddng ho\u1eb7c sau khi h\u00edt ph\u1ea3i ch\u1ea5t k\u00edch th\u00edch.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb ho m\u1ea1n t\u00ednh kh\u00f4ng c\u00f3 \u0111\u1eddm.<\/li>\n<\/ul>\n<figure id=\"attachment_142438\" aria-describedby=\"caption-attachment-142438\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-142438\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/methorfar-15-dieu-tri-cam-lanh.jpg\" alt=\"Methorfar 15 \u0111i\u1ec1u tr\u1ecb c\u1ea3m l\u1ea1nh, ho kh\u00f4ng \u0111\u1eddm\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/methorfar-15-dieu-tri-cam-lanh.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/methorfar-15-dieu-tri-cam-lanh-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/methorfar-15-dieu-tri-cam-lanh-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/methorfar-15-dieu-tri-cam-lanh-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/methorfar-15-dieu-tri-cam-lanh-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-142438\" class=\"wp-caption-text\">Methorfar 15 \u0111i\u1ec1u tr\u1ecb c\u1ea3m l\u1ea1nh, ho kh\u00f4ng \u0111\u1eddm<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Methorfar 15<\/h2>\n<p>Tr\u1ebb em t\u1eeb 3 \u0111\u1ebfn 6 tu\u1ed5i: 1 vi\u00ean\/l\u1ea7n ,2 l\u1ea7n\/ng\u00e0y. T\u1ed1i \u0111a 2 vi\u00ean trong 24 gi\u1edd.<\/p>\n<p>Tr\u1ebb em t\u1eeb 6 \u0111\u1ebfn 12 tu\u1ed5i: 1 vi\u00ean\/l\u1ea7n m\u1ed7i 6 \u0111\u1ebfn 8 gi\u1edd. T\u1ed1i \u0111a 4 vi\u00ean trong 24 gi\u1edd.<\/p>\n<p>Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em tr\u00ean 12 tu\u1ed5i: 2 vi\u00ean\/l\u1ea7n m\u1ed7i 6 \u0111\u1ebfn 8 gi\u1edd. T\u1ed1i \u0111a 8 vi\u00ean trong 24 gi\u1edd.<\/p>\n<p>Ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 suy h\u00f4 h\u1ea5p ho\u1eb7c ng\u01b0\u1eddi c\u00f3 ho kh\u1ea1c \u0111\u00e0m m\u1ee7 kh\u00f4ng n\u00ean d\u00f9ng k\u00e9o d\u00e0i qu\u00e1 7 ng\u00e0y n\u1ebfu kh\u00f4ng c\u00f3 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129.<\/p>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Methorfar 15<\/h2>\n<p>Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Methorfar 15 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Kh\u00f4ng d\u00f9ng Methorfar 15 cho ng\u01b0\u1eddi m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>\u0110ang d\u00f9ng thu\u1ed1c \u1ee9c ch\u1ebf MAO ho\u1eb7c \u0111\u00e3 d\u00f9ng MAOI trong v\u00f2ng 14 ng\u00e0y tr\u01b0\u1edbc \u0111\u00f3.<\/p>\n<p>Tr\u1ebb em d\u01b0\u1edbi 3 tu\u1ed5i.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Methorfar 15<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng cho b\u1ec7nh nh\u00e2n ho c\u00f3 nhi\u1ec1u \u0111\u1eddm ho\u1eb7c ho m\u1ea1n t\u00ednh do h\u00fat thu\u1ed1c hen ph\u1ebf qu\u1ea3n ho\u1eb7c tr\u00e0n kh\u00ed v\u00ec \u1ee9c ch\u1ebf ph\u1ea3n x\u1ea1 ho c\u00f3 th\u1ec3 l\u00e0m \u1ee9 \u0111\u1ecdng \u0111\u1eddm.<\/p>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m ph\u1ea3n x\u1ea1 h\u00f4 h\u1ea5p, c\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng cho b\u1ec7nh nh\u00e2n suy h\u00f4 h\u1ea5p ho\u1eb7c c\u00f3 nguy c\u01a1 suy h\u00f4 h\u1ea5p.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng cho tr\u1ebb em b\u1ecb d\u1ecb \u1ee9ng do ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn c\u00f3 th\u1ec3 x\u1ea3y ra.<\/p>\n<p>C\u1ea3nh b\u00e1o v\u1ec1 nguy c\u01a1 l\u1ea1m d\u1ee5ng v\u00e0 ph\u1ee5 thu\u1ed9c n\u1ebfu d\u00f9ng li\u1ec1u cao k\u00e9o d\u00e0i, nh\u1ea5t l\u00e0 \u1edf thanh thi\u1ebfu ni\u00ean v\u00e0 ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed l\u1ea1m d\u1ee5ng thu\u1ed1c.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p: m\u1ec7t m\u1ecfi, ch\u00f3ng m\u1eb7t, bu\u1ed3n n\u00f4n, \u0111au b\u1ee5ng ho\u1eb7c \u0111\u1ecf b\u1eebng da.<\/p>\n<p>\u00cdt g\u1eb7p: n\u1ed5i m\u1ec1 \u0111ay.<\/p>\n<p>Hi\u1ebfm g\u1eb7p: r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n, \u1ea3o gi\u00e1c, h\u1ed9i ch\u1ee9ng serotonin khi ph\u1ed1i h\u1ee3p v\u1edbi thu\u1ed1c t\u0103ng serotonin.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Tr\u00e1nh d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi thu\u1ed1c \u1ee9c ch\u1ebf MAO do nguy c\u01a1 h\u1ed9i ch\u1ee9ng serotonin v\u00e0 ph\u1ea3n \u1ee9ng n\u1eb7ng.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng thu\u1ed1c \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng v\u00ec c\u00f3 th\u1ec3 t\u0103ng t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf trung \u01b0\u01a1ng v\u00e0 bu\u1ed3n ng\u1ee7.<\/p>\n<p>Quinidine l\u00e0m \u1ee9c ch\u1ebf CYP2D6 v\u00e0 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 dextromethorphan, g\u00e2y t\u0103ng t\u00e1c d\u1ee5ng b\u1ea5t l\u1ee3i. Do \u0111\u00f3 kh\u00f4ng n\u00ean ph\u1ed1i h\u1ee3p.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Tr\u00e1nh d\u00f9ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa.<\/p>\n<h3>Kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Dextromethorphan c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n ng\u1ee7 ho\u1eb7c gi\u1ea3m t\u1ec9nh t\u00e1o. Ng\u01b0\u1eddi d\u00f9ng n\u00ean th\u1eadn tr\u1ecdng khi l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tri\u1ec7u ch\u1ee9ng : bu\u1ed3n n\u00f4n, n\u00f4n, bu\u1ed3n ng\u1ee7, nh\u00ecn m\u1edd, rung gi\u1eadt nh\u00e3n c\u1ea7u, b\u00ed ti\u1ec3u, \u1ea3o gi\u00e1c, m\u1ea5t \u0111i\u1ec1u h\u00f2a, suy h\u00f4 h\u1ea5p v\u00e0 co gi\u1eadt.<\/p>\n<p>X\u1eed tr\u00ed : B\u00e1o ngay v\u1edbi b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng k\u1ecbp th\u1eddi. H\u1ed7 tr\u1ee3 h\u00f4 h\u1ea5p tu\u1ea7n ho\u00e0n v\u00e0 theo d\u00f5i li\u00ean t\u1ee5c. C\u00e2n nh\u1eafc th\u1edf m\u00e1y n\u1ebfu c\u1ea7n v\u00e0 \u0111i\u1ec1u tr\u1ecb co gi\u1eadt b\u1eb1ng benzodiazepin.<\/p>\n<h2>B\u1ea3o qu\u1ea3n<\/h2>\n<p>B\u1ea3o qu\u1ea3n thu\u1ed1c \u1edf n\u01a1i kh\u00f4 m\u00e1t, tr\u00e1nh \u00e1nh s\u00e1ng, nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30\u00b0C.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng v\u1edbi nh\u01b0:<\/p>\n<ul>\n<li>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/rodilar-15mg\/\">Rodilar 15mg<\/a> d\u00f9ng \u0111\u1ec3 l\u00e0m gi\u1ea3m ho khan, ho do k\u00edch \u1ee9ng ni\u00eam m\u1ea1c h\u1ecdng v\u00e0 ph\u1ebf qu\u1ea3n trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p c\u1ea3m l\u1ea1nh ho\u1eb7c khi ti\u1ebfp x\u00fac v\u1edbi t\u00e1c nh\u00e2n g\u00e2y k\u00edch th\u00edch \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p.<\/li>\n<li>Thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/dexipharm-15mg-chai-500-vien\/\">Dexipharm 15mg<\/a> (Chai 500 vi\u00ean) c\u1ee7a c\u00f4ng ty Imexpharm s\u1ea3n xu\u1ea5t, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111i\u1ec1u tr\u1ecb ho c\u1ea5p t\u00ednh, ho m\u1ea1n t\u00ednh, ho kh\u00f4ng c\u00f3 \u0111\u1eddm,\u2026<\/li>\n<\/ul>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Bolser D. C. (2009). Central mechanisms II: pharmacology of brainstem pathways. Truy c\u1eadp ng\u00e0y 29\/09\/2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18825342\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/18825342\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Methorfar 15 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng ho khan do h\u1ecdng v\u00e0 ph\u1ebf qu\u1ea3n b\u1ecb k\u00edch th\u00edch trong c\u1ea3m l\u1ea1nh th\u00f4ng th\u01b0\u1eddng ho\u1eb7c sau khi h\u00edt ph\u1ea3i ch\u1ea5t k\u00edch th\u00edch.<\/p>\n","protected":false},"author":1,"featured_media":142439,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-142437","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/142437","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=142437"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/142439"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=142437"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=142437"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=142437"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}