{"id":142330,"date":"2025-09-29T08:05:28","date_gmt":"2025-09-29T01:05:28","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=142330"},"modified":"2025-09-29T08:11:06","modified_gmt":"2025-09-29T01:11:06","slug":"rotalzon-50mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/rotalzon-50mg\/","title":{"rendered":"Rotalzon 50mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <a href=\"https:\/\/vnras.com\/drug\/\">d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Rotalzon 50mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Atlantic Pharma \u2013 Produ\u00e7\u00f5es Farmac\u00eauticas S.A c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 560110018425 (S\u0110K c\u0169: VN-16196-13)<\/strong><\/p>\n<h2>Rotalzon 50mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ng Rotalzon 50mg<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Losartan potassium&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;50mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: Cellulose vi tinh th\u1ec3, tinh b\u1ed9t bi\u1ebfn t\u00ednh, silica keo khan, talc tinh ch\u1ebf, magie stearat, ch\u1ea5t m\u00e0u II Pink 85G54105, s\u00e1p carnauba.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 560110018425 (S\u0110K c\u0169: VN-16196-13)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 6 v\u1ec9 x 10 Vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: B\u1ed3 \u0110\u00e0o Nha<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Rotalzon 50mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Losartan l\u00e0 ho\u1ea1t ch\u1ea5t thu\u1ed9c nh\u00f3m \u0111\u1ed1i kh\u00e1ng th\u1ee5 th\u1ec3 angiotensin II, \u0111\u1eb7c hi\u1ec7u tr\u00ean typ AT\u2081, v\u00e0 c\u0169ng l\u00e0 thu\u1ed1c \u0111\u1ea7u ti\u00ean \u0111\u1ea1i di\u1ec7n cho nh\u00f3m n\u00e0y.<\/p>\n<p>Angiotensin II v\u1ed1n l\u00e0 ch\u1ea5t co m\u1ea1ch r\u1ea5t m\u1ea1nh, \u0111\u01b0\u1ee3c t\u1ea1o th\u00e0nh nh\u1edd enzym chuy\u1ec3n angiotensin (ACE). Ho\u1ea1t ch\u1ea5t n\u00e0y kh\u00f4ng ch\u1ec9 tham gia quan tr\u1ecdng trong ti\u1ebfn tr\u00ecnh h\u00ecnh th\u00e0nh t\u0103ng huy\u1ebft \u00e1p m\u00e0 c\u00f2n k\u00edch th\u00edch tuy\u1ebfn th\u01b0\u1ee3ng th\u1eadn s\u1ea3n xu\u1ea5t aldosteron.<\/p>\n<p>Losartan c\u00f9ng v\u1edbi ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd s\u1ebd ng\u0103n c\u1ea3n ch\u1ecdn l\u1ecdc s\u1ef1 g\u1eafn k\u1ebft c\u1ee7a angiotensin II l\u00ean th\u1ee5 th\u1ec3 AT\u2081 t\u1ea1i th\u00e0nh m\u1ea1ch v\u00e0 tuy\u1ebfn th\u01b0\u1ee3ng th\u1eadn, nh\u1edd v\u1eady \u1ee9c ch\u1ebf c\u1ea3 ph\u1ea3n \u1ee9ng co m\u1ea1ch v\u00e0 qu\u00e1 tr\u00ecnh ti\u1ebft aldosteron.<\/p>\n<p>Ch\u1ea5t chuy\u1ec3n h\u00f3a n\u00e0y c\u00f2n c\u00f3 hi\u1ec7u l\u1ef1c d\u01b0\u1ee3c l\u00fd cao h\u01a1n thu\u1ed1c g\u1ed1c t\u1eeb 10 \u0111\u1ebfn 40 l\u1ea7n.<\/p>\n<p>Kh\u00e1c v\u1edbi nh\u00f3m thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n, losartan \u00edt g\u00e2y t\u00e1c d\u1ee5ng ph\u1ee5 ho khan \u2013 m\u1ed9t \u0111i\u1ec3m thu\u1eadn l\u1ee3i trong \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>D\u00f9ng qua \u0111\u01b0\u1eddng u\u1ed1ng, losartan \u0111\u01b0\u1ee3c h\u1ea5p thu hi\u1ec7u qu\u1ea3; tuy v\u1eady, s\u1ef1 chuy\u1ec3n h\u00f3a qua gan l\u00e0m gi\u1ea3m sinh kh\u1ea3 d\u1ee5ng, ch\u1ec9 c\u00f2n kho\u1ea3ng m\u1ed9t ph\u1ea7n ba<\/p>\n<p>Kho\u1ea3ng 14% li\u1ec1u u\u1ed1ng c\u1ee7a ho\u1ea1t ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c chuy\u1ec3n th\u00e0nh ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh, \u0111\u00e2y l\u00e0 th\u00e0nh ph\u1ea7n ch\u00ednh t\u1ea1o t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd c\u1ee7a thu\u1ed1c<\/p>\n<p>N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh c\u1ee7a Losartan \u0111\u1ea1t sau 1 gi\u1edd, ch\u1ea5t chuy\u1ec3n h\u00f3a sau 3\u20134 gi\u1edd.<\/p>\n<p>Th\u1eddi gian b\u00e1n th\u1ea3i: Losartan kho\u1ea3ng v\u00e0i gi\u1edd, ch\u1ea5t chuy\u1ec3n h\u00f3a 6\u20139 gi\u1edd.<\/p>\n<p>Thu\u1ed1c li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (ch\u1ee7 y\u1ebfu albumin), th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 (Vd=34L) \u0111\u1ed1i v\u1edbi Losartan v\u00e0 Vd=12L \u0111\u1ed1i v\u1edbi ch\u1ea5t chuy\u1ec3n h\u00f3a.<\/p>\n<p>B\u00e0i ti\u1ebft qua n\u01b0\u1edbc ti\u1ec3u (kho\u1ea3ng 35%) v\u00e0 ph\u00e2n (kho\u1ea3ng 60%).<\/p>\n<p>\u1ede b\u1ec7nh nh\u00e2n x\u01a1 gan m\u1ee9c \u0111\u1ed9 nh\u1eb9\u2013v\u1eeba, AUC c\u1ee7a Losartan t\u0103ng g\u1ea5p 5 l\u1ea7n v\u00e0 c\u1ee7a ch\u1ea5t chuy\u1ec3n h\u00f3a t\u0103ng g\u1ea5p 2 l\u1ea7n.<\/p>\n<h2>Thu\u1ed1c Rotalzon 50mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>\u0110i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p (d\u00f9ng \u0111\u01a1n \u0111\u1ed9c ho\u1eb7c ph\u1ed1i h\u1ee3p v\u1edbi thu\u1ed1c h\u1ea1 \u00e1p kh\u00e1c, k\u1ec3 c\u1ea3 l\u1ee3i ti\u1ec3u).<\/p>\n<p>H\u1ea1 nguy c\u01a1 tai bi\u1ebfn m\u1ea1ch m\u00e1u n\u00e3o \u1edf b\u1ec7nh nh\u00e2n t\u0103ng huy\u1ebft \u00e1p c\u00f3 xu\u1ea5t hi\u1ec7n ph\u00ec \u0111\u1ea1i th\u1ea5t tr\u00e1i.<\/p>\n<p>Ki\u1ec3m so\u00e1t b\u1ec7nh th\u1eadn tr\u00ean b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng typ 2, khi ng\u01b0\u1eddi b\u1ec7nh c\u00f3 s\u1ef1 gia t\u0103ng creatinin huy\u1ebft thanh c\u00f9ng v\u1edbi protein ni\u1ec7u n\u1eb7ng (t\u1ef7 l\u1ec7 albumin\/creatinin \u2265 300 mg\/g)<\/p>\n<figure id=\"attachment_142343\" aria-describedby=\"caption-attachment-142343\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-142343\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Rotalzon-50mg.jpg\" alt=\"Rotalzon 50mg\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Rotalzon-50mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Rotalzon-50mg-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Rotalzon-50mg-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Rotalzon-50mg-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Rotalzon-50mg-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-142343\" class=\"wp-caption-text\">Thu\u1ed1c Rotalzon 50mg c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00e0 gi\u1ea3m nguy c\u01a1 \u0111\u1ed9t qu\u1ef5<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c t\u00ednh cho vi\u00ean n\u00e9n Rotalzon 50mg<\/p>\n<p>T\u0103ng huy\u1ebft \u00e1p: Li\u1ec1u kh\u1edfi \u0111\u1ea7u v\u00e0 duy tr\u00ec th\u00f4ng th\u01b0\u1eddng ng\u00e0y 1 vi\u00ean. C\u00f3 th\u1ec3 t\u0103ng t\u1edbi ng\u00e0y 2 vi\u00ean t\u00f9y \u0111\u00e1p \u1ee9ng.<\/p>\n<p>B\u1ec7nh nh\u00e2n gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n (d\u00f9ng l\u1ee3i ti\u1ec3u li\u1ec1u cao\u2026): b\u1eaft \u0111\u1ea7u v\u1edbi li\u1ec1u ng\u00e0y 1 n\u1eeda vi\u00ean.<\/p>\n<p>Ph\u00ec \u0111\u1ea1i th\u1ea5t tr\u00e1i: Li\u1ec1u kh\u1edfi \u0111\u1ea7u ng\u00e0y 1 vi\u00ean, c\u00f3 th\u1ec3 ph\u1ed1i h\u1ee3p v\u1edbi hydrochlorothiazide ho\u1eb7c t\u0103ng li\u1ec1u ng\u00e0y 2 vi\u00ean<\/p>\n<p>B\u1ea3o v\u1ec7 th\u1eadn \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng typ 2 c\u00f3 protein ni\u1ec7u: Li\u1ec1u kh\u1edfi \u0111\u1ea7u ng\u00e0y 1 vi\u00ean, c\u00f3 th\u1ec3 t\u0103ng l\u00ean ng\u00e0y 2 vi\u00ean t\u00f9y \u0111\u00e1p \u1ee9ng.<\/p>\n<p>Ng\u01b0\u1eddi cao tu\u1ed5i v\u00e0 b\u1ec7nh nh\u00e2n suy th\u1eadn (k\u1ec3 c\u1ea3 ch\u1ea1y th\u1eadn): d\u00f9ng nh\u01b0 ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng<\/p>\n<p>B\u1ec7nh nh\u00e2n suy gan: C\u1ea7n xem x\u00e9t gi\u1ea3m li\u1ec1u Rotalzon d\u01b0\u1edbi s\u1ef1 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129<\/p>\n<p>Tr\u1ebb em: V\u1edbi tr\u1ebb t\u1eeb 1 th\u00e1ng \u0111\u1ebfn 16 tu\u1ed5i, li\u1ec1u 0,54\u20130,77 mg\/kg\/ng\u00e0y, t\u1ed1i \u0111a ng\u00e0y 1 vi\u00ean (tr\u1ebb &lt;50kg); c\u00f3 th\u1ec3 t\u0103ng \u0111\u1ebfn ng\u00e0y 2 vi\u00ean cho tr\u1ebb \u226550kg.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>U\u1ed1ng nguy\u00ean <strong>vi\u00ean n\u00e9n Rotalzon 50mg<\/strong> v\u1edbi n\u01b0\u1edbc v\u00e0o b\u1ea5t c\u1ee9 th\u1eddi \u0111i\u1ec3m n\u00e0o trong ng\u00e0y \u0111\u1ec3 thu\u1eadn l\u1ee3i vi\u1ec7c d\u00f9ng thu\u1ed1c l\u00e0 \u0111\u01b0\u1ee3c<\/p>\n<p>C\u00f3 th\u1ec3 ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c h\u1ea1 \u00e1p kh\u00e1c (l\u1ee3i ti\u1ec3u, ch\u1eb9n k\u00eanh calci, \u1ee9c ch\u1ebf alpha, beta, thu\u1ed1c t\u00e1c \u0111\u1ed9ng trung \u01b0\u01a1ng) ho\u1eb7c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng (insulin, sulfonylurea, glitazone, \u1ee9c ch\u1ebf glucosidase).<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Rotalzon 50mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi m\u1eabn c\u1ea3m v\u1edbi Losartan ho\u1eb7c t\u00e1 d\u01b0\u1ee3c c\u00f3 trong vi\u00ean u\u1ed1ng Rotalzon 50mg<\/p>\n<p>Ph\u1ee5 n\u1eef \u0111ang trong chu k\u1ef3 thai \u1edf 3 th\u00e1ng gi\u1eefa v\u00e0 3 th\u00e1ng cu\u1ed1i<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Nguy c\u01a1 g\u00e2y h\u1ea1i cho thai nhi n\u1ebfu d\u00f9ng trong thai k\u1ef3 (gi\u1ea3m s\u1ea3n n\u00e3o, suy th\u1eadn, thi\u1ec3u \u1ed1i, bi\u1ebfn d\u1ea1ng x\u01b0\u01a1ng s\u1ecd, t\u1eed vong).<\/p>\n<p>Ng\u01b0\u1eddi c\u00f3 gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n d\u1ec5 b\u1ecb h\u1ea1 huy\u1ebft \u00e1p khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>B\u1ec7nh nh\u00e2n suy gan: n\u1ed3ng \u0111\u1ed9 Losartan trong huy\u1ebft t\u01b0\u01a1ng t\u0103ng cao, c\u1ea7n gi\u1ea3m li\u1ec1u.<\/p>\n<p>Ng\u01b0\u1eddi c\u00f3 b\u1ec7nh th\u1eadn: thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m thay \u0111\u1ed5i ch\u1ee9c n\u0103ng th\u1eadn, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n h\u1eb9p \u0111\u1ed9ng m\u1ea1ch th\u1eadn.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p: ch\u00f3ng m\u1eb7t, hoa m\u1eaft, m\u1ec7t m\u1ecfi.<\/p>\n<p>\u00cdt g\u1eb7p: t\u1ee5t huy\u1ebft \u00e1p, t\u0103ng kali m\u00e1u.<\/p>\n<p>Hi\u1ebfm g\u1eb7p: ph\u00f9 m\u1ea1ch (m\u1eb7t, m\u00f4i, thanh qu\u1ea3n\u2026), vi\u00eam gan, gi\u1ea3m ti\u1ec3u c\u1ea7u, thi\u1ebfu m\u00e1u, vi\u00eam c\u01a1, \u0111au kh\u1edbp, n\u1ed5i m\u00e0y \u0111ay, ng\u1ee9a, \u0111au n\u1eeda \u0111\u1ea7u.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Rifampin, Fluconazole: khi d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi losartan c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 n\u1ed3ng \u0111\u1ed9 c\u1ee7a ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh, t\u1eeb \u0111\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb. V\u00ec v\u1eady, n\u1ebfu c\u1ea7n ph\u1ed1i h\u1ee3p, b\u00e1c s\u0129 n\u00ean l\u01b0u \u00fd kh\u1ea3 n\u0103ng gi\u1ea3m t\u00e1c d\u1ee5ng ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p.<\/p>\n<p>Thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n (ACE inhibitors): ph\u1ed1i h\u1ee3p c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 xu\u1ea5t hi\u1ec7n t\u00ecnh tr\u1ea1ng t\u0103ng kali m\u00e1u, \u0111\u1ed3ng th\u1eddi l\u00e0m n\u1eb7ng th\u00eam nguy c\u01a1 suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn v\u00e0 g\u00e2y h\u1ea1 huy\u1ebft \u00e1p. C\u1ea7n th\u1eadn tr\u1ecdng \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn ho\u1eb7c \u0111ang d\u00f9ng \u0111\u1ed3ng th\u1eddi nhi\u1ec1u thu\u1ed1c.<\/p>\n<p>Thu\u1ed1c l\u1ee3i ti\u1ec3u: khi ph\u1ed1i h\u1ee3p, \u0111\u1eb7c bi\u1ec7t l\u00e0 trong giai \u0111o\u1ea1n b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb, c\u00f3 th\u1ec3 g\u00e2y t\u1ee5t huy\u1ebft \u00e1p m\u1ea1nh do t\u00e1c d\u1ee5ng hi\u1ec7p \u0111\u1ed3ng. Ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i huy\u1ebft \u00e1p th\u01b0\u1eddng xuy\u00ean \u0111\u1ec3 tr\u00e1nh c\u00e1c bi\u1ebfn ch\u1ee9ng.<\/p>\n<p>Thu\u1ed1c l\u1ee3i ti\u1ec3u gi\u1eef kali (v\u00ed d\u1ee5: spironolacton, eplerenon, amilorid): d\u00f9ng chung v\u1edbi losartan d\u1ec5 d\u1eabn t\u1edbi t\u0103ng kali huy\u1ebft. Nguy c\u01a1 n\u00e0y c\u00e0ng cao \u1edf ng\u01b0\u1eddi c\u00f3 r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng th\u1eadn, do \u0111\u00f3 c\u1ea7n gi\u00e1m s\u00e1t ch\u1eb7t n\u1ed3ng \u0111\u1ed9 kali huy\u1ebft.<\/p>\n<p>Lithium: khi ph\u1ed1i h\u1ee3p, n\u1ed3ng \u0111\u1ed9 lithium trong m\u00e1u c\u00f3 th\u1ec3 t\u0103ng l\u00ean \u0111\u00e1ng k\u1ec3, d\u1ec5 g\u00e2y \u0111\u1ed9c t\u00ednh. V\u00ec v\u1eady, n\u1ebfu b\u1eaft bu\u1ed9c ph\u1ea3i d\u00f9ng chung, c\u1ea7n x\u00e9t nghi\u1ec7m \u0111\u1ecbnh k\u1ef3 n\u1ed3ng \u0111\u1ed9 lithium \u0111\u1ec3 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u th\u00edch h\u1ee3p.<\/p>\n<p>NSAIDs (bao g\u1ed3m c\u1ea3 c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc COX-2): c\u00f3 th\u1ec3 l\u00e0m suy gi\u1ea3m t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a losartan v\u00e0 \u0111\u1ed3ng th\u1eddi l\u00e0m t\u0103ng nguy c\u01a1 suy th\u1eadn, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n cao tu\u1ed5i ho\u1eb7c \u0111\u00e3 c\u00f3 s\u1eb5n r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng th\u1eadn. Khuy\u1ebfn c\u00e1o n\u00ean theo d\u00f5i th\u01b0\u1eddng xuy\u00ean ch\u1ee9c n\u0103ng th\u1eadn v\u00e0 t\u00ecnh tr\u1ea1ng huy\u1ebft \u00e1p khi ph\u1ed1i h\u1ee3p.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p><em><strong>Trong thai k\u1ef3<\/strong><\/em><\/p>\n<p>Ho\u1ea1t ch\u1ea5t ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 ho\u00e0n to\u00e0n an to\u00e0n khi d\u00f9ng cho ph\u1ee5 n\u1eef mang thai, v\u00ec v\u1eady ch\u1ec9 n\u00ean c\u00e2n nh\u1eafc s\u1eed d\u1ee5ng Rotalzon 50mg trong tr\u01b0\u1eddng h\u1ee3p th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft v\u00e0 khi l\u1ee3i \u00edch mang l\u1ea1i cho m\u1eb9 v\u01b0\u1ee3t tr\u1ed9i so v\u1edbi nguy c\u01a1 ti\u1ec1m \u1ea9n cho thai nhi.<\/p>\n<p><em><strong>Khi cho con b\u00fa<\/strong><\/em><\/p>\n<p>Ch\u01b0a c\u00f3 \u0111\u1ee7 b\u1eb1ng ch\u1ee9ng v\u1ec1 vi\u1ec7c ho\u1ea1t ch\u1ea5t c\u1ee7a thu\u1ed1c Rotalzon 50mg c\u00f3 b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9 hay \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn tr\u1ebb s\u01a1 sinh b\u00fa m\u1eb9.<\/p>\n<p>Do \u0111\u00f3, c\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng Rotalzon cho ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa; c\u00f3 th\u1ec3 c\u00e2n nh\u1eafc ng\u1eebng cho tr\u1ebb b\u00fa s\u1eefa c\u1ee7a m\u1eb9 ho\u1eb7c m\u1eb9 t\u1ea1m d\u1eebng d\u00f9ng thu\u1ed1c t\u00f9y theo m\u1ee9c \u0111\u1ed9 c\u1ea7n thi\u1ebft c\u1ee7a vi\u1ec7c \u0111i\u1ec1u tr\u1ecb cho ng\u01b0\u1eddi m\u1eb9.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n nghi ng\u1edd li\u00ean quan \u0111\u1ebfn Rotalzon\u00a0c\u00f3 th\u1ec3 x\u1ea3y ra trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb nh\u01b0 ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, bu\u1ed3n ng\u1ee7 ho\u1eb7c r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c.<\/p>\n<p>C\u00e1c tri\u1ec7u ch\u1ee9ng n\u00e0y c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m gi\u1ea3m s\u1ef1 t\u1eadp trung, ph\u1ea3n x\u1ea1 v\u00e0 kh\u1ea3 n\u0103ng ph\u1ed1i h\u1ee3p \u0111\u1ed9ng t\u00e1c, t\u1eeb \u0111\u00f3 \u1ea3nh h\u01b0\u1edfng tr\u1ef1c ti\u1ebfp \u0111\u1ebfn vi\u1ec7c l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<p>Do v\u1eady, ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o n\u00ean th\u1eadn tr\u1ecdng, tr\u00e1nh \u0111i\u1ec1u khi\u1ec3n ph\u01b0\u01a1ng ti\u1ec7n ho\u1eb7c l\u00e0m vi\u1ec7c v\u1edbi m\u00e1y m\u00f3c nguy hi\u1ec3m cho \u0111\u1ebfn khi bi\u1ebft ch\u1eafc ch\u1eafn thu\u1ed1c kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn b\u1ea3n th\u00e2n.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p><em><strong>Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u<\/strong><\/em><\/p>\n<p>Khi d\u00f9ng li\u1ec1u cao Lorsatan qu\u00e1 m\u1ee9c, ng\u01b0\u1eddi b\u1ec7nh c\u00f3 th\u1ec3 g\u1eb7p c\u00e1c bi\u1ec3u hi\u1ec7n nh\u01b0 bu\u1ed3n n\u00f4n, n\u00f4n, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a, r\u1ed1i lo\u1ea1n th\u1ea7n kinh trung \u01b0\u01a1ng (ch\u00f3ng m\u1eb7t, l\u00fa l\u1eabn, co gi\u1eadt), ho\u1eb7c r\u1ed1i lo\u1ea1n tim m\u1ea1ch (lo\u1ea1n nh\u1ecbp, t\u1ee5t huy\u1ebft \u00e1p).<\/p>\n<p>M\u1ee9c \u0111\u1ed9 n\u1eb7ng nh\u1eb9 c\u1ee7a tri\u1ec7u ch\u1ee9ng ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec1u \u0111\u00e3 s\u1eed d\u1ee5ng c\u0169ng nh\u01b0 t\u00ecnh tr\u1ea1ng s\u1ee9c kh\u1ecfe n\u1ec1n c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh.<\/p>\n<p><em><strong>Nguy\u00ean t\u1eafc x\u1eed tr\u00ed<\/strong><\/em><\/p>\n<p>Hi\u1ec7n ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u cho ho\u1ea1t ch\u1ea5t ch\u00ednh c\u1ee7a Rotalzon, \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 v\u00e0 tri\u1ec7u ch\u1ee9ng l\u00e0 c\u00e1ch l\u00e0m ch\u1ee7 y\u1ebfu.<\/p>\n<p>C\u00f3 th\u1ec3 \u00e1p d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p lo\u1ea1i b\u1ecf ho\u1ea1t to\u00e0n ho\u1ea1t ch\u1ea5t ch\u00ednh c\u1ee7a thu\u1ed1c kh\u1ecfi c\u01a1 th\u1ec3 nh\u01b0 r\u1eeda d\u1ea1 d\u00e0y, than ho\u1ea1t t\u00ednh trong giai \u0111o\u1ea1n s\u1edbm sau khi u\u1ed1ng.<\/p>\n<p>Ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i s\u00e1t t\u00ecnh tr\u1ea1ng h\u00f4 h\u1ea5p, tu\u1ea7n ho\u00e0n, x\u1eed l\u00fd ngay khi c\u00f3 bi\u1ec3u hi\u1ec7n b\u1ea5t th\u01b0\u1eddng v\u00e0 nhanh ch\u00f3ng chuy\u1ec3n \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf \u0111\u1ec3 \u0111\u01b0\u1ee3c c\u1ea5p c\u1ee9u.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Rotalzon 50mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Rotalzon 50mg trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Rotalzon 50mg khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Rotalzon 50mg nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/losartan-stada-50-mg\/\">Losartan Stada 50 mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Losartan kali 50 mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH LD Stada-Vi\u1ec7t Nam, \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p, b\u1ec7nh th\u1eadn \u1edf ng\u01b0\u1eddi \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/savi-losartan-50\/\">Savi Losartan 50<\/a>\u00a0c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Losartan kali 50 mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m SaVi, \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p, b\u1ec7nh th\u1eadn \u1edf ng\u01b0\u1eddi \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Rotalzon 50mg \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/To-huong-dan-su-dung-Rotalzon-50mg-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 29 th\u00e1ng 9 n\u0103m 2025<\/li>\n<li>Goldberg A, Sweet C (1995). Efficacy and safety of losartan. Can J Cardiol. Truy c\u1eadp ng\u00e0y 29 th\u00e1ng 9 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7664215\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/7664215\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Rotalzon 50mg \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p, gi\u1ea3m nguy c\u01a1 \u0111\u1ed9t qu\u1ef5 \u1edf b\u1ec7nh nh\u00e2n t\u0103ng huy\u1ebft \u00e1p k\u00e8m ph\u00ec \u0111\u1ea1i th\u1ea5t tr\u00e1i, v\u00e0 b\u1ea3o v\u1ec7 ch\u1ee9c n\u0103ng th\u1eadn \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng c\u00f3 protein ni\u1ec7u<\/p>\n","protected":false},"author":1,"featured_media":142342,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-142330","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/142330","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=142330"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/142342"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=142330"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=142330"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=142330"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}