{"id":141249,"date":"2025-09-26T12:51:32","date_gmt":"2025-09-26T05:51:32","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=141249"},"modified":"2025-09-26T13:27:21","modified_gmt":"2025-09-26T06:27:21","slug":"nitidine-15mg-ml-phuong-dong","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/nitidine-15mg-ml-phuong-dong\/","title":{"rendered":"Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <a href=\"https:\/\/vnras.com\/drug\/\">d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty d\u01b0\u1ee3c ph\u1ea9m v\u00e0 th\u01b0\u01a1ng m\u1ea1i Ph\u01b0\u01a1ng \u0110\u00f4ng &#8211; (TNHH) c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-35957-22<\/strong><\/p>\n<h2>Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i 1 ml <strong>dung d\u1ecbch Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Nizatidin:&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;..15mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: Natri citrat, acid citric, tartrazin, acid benzoic, glycerin, polysorbat 80, natri saccharin, dung d\u1ecbch h\u01b0\u01a1ng cam, n\u01b0\u1edbc tinh khi\u1ebft.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Dung d\u1ecbch u\u1ed1ng<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-35957-22<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 \u1ed1ng x 10ml<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Nizatidin ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u0111\u1ed1i kh\u00e1ng ch\u1ecdn l\u1ecdc t\u1ea1i th\u1ee5 th\u1ec3 H\u2082 tr\u00ean t\u1ebf b\u00e0o th\u00e0nh d\u1ea1 d\u00e0y, t\u1eeb \u0111\u00f3 \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh ti\u1ebft acid. Thu\u1ed1c l\u00e0m gi\u1ea3m ti\u1ebft d\u1ecbch v\u1ecb c\u1ea3 khi \u0111\u00f3i l\u1eabn khi c\u00f3 k\u00edch th\u00edch b\u1edfi th\u1ee9c \u0103n ho\u1eb7c c\u00e1c ch\u1ea5t nh\u01b0 histamin, cafein, insulin. So v\u1edbi cimetidin, t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf c\u1ee7a nizatidin m\u1ea1nh g\u1ea5p nhi\u1ec1u l\u1ea7n v\u00e0 c\u00f3 hi\u1ec7u qu\u1ea3 t\u01b0\u01a1ng t\u1ef1 ranitidin. Sau khi u\u1ed1ng li\u1ec1u 300mg, m\u1ee9c ti\u1ebft acid ban \u0111\u00eam gi\u1ea3m t\u1edbi 90% trong kho\u1ea3ng 10 gi\u1edd, c\u00f2n ti\u1ebft acid do th\u1ee9c \u0103n k\u00edch th\u00edch gi\u1ea3m kho\u1ea3ng 97% trong 4 gi\u1edd. Ngo\u00e0i ra, vi\u1ec7c gi\u1ea3m ti\u1ebft acid c\u00f2n k\u00e9o theo gi\u1ea3m s\u1ea3n xu\u1ea5t pepsin, gi\u00fap b\u1ea3o v\u1ec7 ni\u00eam m\u1ea1c d\u1ea1 d\u00e0y kh\u1ecfi t\u1ed5n th\u01b0\u01a1ng.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Nizatidin \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh qua \u0111\u01b0\u1eddng u\u1ed1ng v\u1edbi sinh kh\u1ea3 d\u1ee5ng x\u1ea5p x\u1ec9 l\u00e0 70%. Th\u1ee9c \u0103n c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nh\u1eb9, trong khi thu\u1ed1c kh\u00e1ng acid c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m nh\u1eb9 m\u1ee9c h\u1ea5p thu nh\u01b0ng kh\u00f4ng \u0111\u00e1ng k\u1ec3 v\u1ec1 m\u1eb7t l\u00e2m s\u00e0ng.<\/p>\n<p>Ph\u00e2n b\u1ed1: Kho\u1ea3ng 35% ho\u1ea1t ch\u1ea5t Nizatidin g\u1eafn v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng, th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 t\u1eeb 0,8 \u2013 1,5 l\u00edt\/kg. Nizatidin c\u00f3 kh\u1ea3 n\u0103ng \u0111i qua nhau thai v\u00e0 b\u00e0i ti\u1ebft m\u1ed9t l\u01b0\u1ee3ng \u00edt v\u00e0o s\u1eefa m\u1eb9.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Nizatidin ch\u1ec9 chuy\u1ec3n h\u00f3a m\u1ed9t ph\u1ea7n nh\u1ecf \u1edf gan, t\u1ea1o th\u00e0nh c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a nh\u01b0 N-2-oxyd, S-oxyd v\u00e0 N-2-monodesmethylnizatidin (ch\u1ea5t n\u00e0y c\u00f2n gi\u1eef kho\u1ea3ng 60% ho\u1ea1t t\u00ednh so v\u1edbi thu\u1ed1c g\u1ed1c).<\/p>\n<p>Th\u1ea3i tr\u1eeb: Th\u1eddi gian b\u00e1n th\u1ea3i trung b\u00ecnh c\u1ee7a Nizatidin l\u00e0 t\u1eeb 1 \u2013 2 gi\u1edd, k\u00e9o d\u00e0i h\u01a1n \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn. H\u01a1n 90% li\u1ec1u ho\u1ea1t ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u trong v\u00f2ng 12 \u2013 16 gi\u1edd, ch\u1ee7 y\u1ebfu \u1edf d\u1ea1ng c\u00f2n nguy\u00ean v\u1eb9n; m\u1ed9t ph\u1ea7n nh\u1ecf (d\u01b0\u1edbi 6%) \u0111\u01b0\u1ee3c th\u1ea3i qua ph\u00e2n.<\/p>\n<h2>Thu\u1ed1c Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Lo\u00e9t t\u00e1 tr\u00e0ng ti\u1ebfn tri\u1ec3n<\/p>\n<p>D\u1ef1 ph\u00f2ng t\u00e1i ph\u00e1t lo\u00e9t t\u00e1 tr\u00e0ng sau khi \u0111\u00e3 \u0111i\u1ec1u tr\u1ecb li\u1ec1n s\u1eb9o<\/p>\n<p>Lo\u00e9t d\u1ea1 d\u00e0y l\u00e0nh t\u00ednh, bao g\u1ed3m lo\u00e9t do stress ho\u1eb7c do d\u00f9ng thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid (NSAID)<\/p>\n<p>Tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y \u2013 th\u1ef1c qu\u1ea3n<\/p>\n<p>H\u1ed9i ch\u1ee9ng Zollinger \u2013 Ellison<\/p>\n<p>Gi\u1ea3m tri\u1ec7u ch\u1ee9ng r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a do t\u0103ng ti\u1ebft acid c\u00f3 th\u1ec3 k\u1ec3 \u0111\u1ebfn nh\u01b0 \u1ee3 n\u00f3ng, \u1ee3 chua, kh\u00f3 ti\u00eau<\/p>\n<figure id=\"attachment_141258\" aria-describedby=\"caption-attachment-141258\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-141258\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Nitidine-15mgml-Phuong-Dong.jpg\" alt=\"Nitidine 15mg\/ml Phu\u031bo\u031bng \u0110o\u0302ng\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Nitidine-15mgml-Phuong-Dong.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Nitidine-15mgml-Phuong-Dong-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Nitidine-15mgml-Phuong-Dong-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Nitidine-15mgml-Phuong-Dong-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Nitidine-15mgml-Phuong-Dong-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-141258\" class=\"wp-caption-text\">Thu\u1ed1c Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y, t\u00e1 tr\u00e0ng<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p><em><strong>Ng\u01b0\u1eddi l\u1edbn<\/strong><\/em><\/p>\n<p>Lo\u00e9t d\u1ea1 d\u00e0y \u2013 t\u00e1 tr\u00e0ng: 300mg\/ng\u00e0y (t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi 2 \u1ed1ng\/ng\u00e0y), c\u00f3 th\u1ec3 u\u1ed1ng 1 l\u1ea7n bu\u1ed5i t\u1ed1i ho\u1eb7c chia 2 l\u1ea7n s\u00e1ng \u2013 t\u1ed1i, d\u00f9ng trong 4 \u2013 8 tu\u1ea7n.<\/p>\n<p>Tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y \u2013 th\u1ef1c qu\u1ea3n: 150mg x 2 l\u1ea7n\/ng\u00e0y (t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi 1 \u1ed1ng x 2 l\u1ea7n\/ng\u00e0y), \u0111i\u1ec1u tr\u1ecb trong 12 tu\u1ea7n. C\u00f3 th\u1ec3 d\u00f9ng 300mg v\u00e0o bu\u1ed5i t\u1ed1i, nh\u01b0ng th\u01b0\u1eddng chia 2 l\u1ea7n s\u1ebd hi\u1ec7u qu\u1ea3 h\u01a1n.<\/p>\n<p>Lo\u00e9t do Helicobacter pylori: ph\u1ed1i h\u1ee3p v\u1edbi kh\u00e1ng sinh (amoxicillin, tetracyclin, clarithromycin, metronidazol).<\/p>\n<p>Gi\u1ea3m tri\u1ec7u ch\u1ee9ng kh\u00f3 ti\u00eau: 75mg\/l\u1ea7n (t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi \u00bd \u1ed1ng\/l\u1ea7n), c\u00f3 th\u1ec3 d\u00f9ng nh\u1eafc l\u1ea1i khi c\u1ea7n, t\u1ed1i \u0111a 1 \u1ed1ng\/ng\u00e0y trong 14 ng\u00e0y.<\/p>\n<p><em><strong>Tr\u1ebb em \u2265 12 tu\u1ed5i<\/strong><\/em><\/p>\n<p>Tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y \u2013 th\u1ef1c qu\u1ea3n: 150mg x 2 l\u1ea7n\/ng\u00e0y (t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi 1 \u1ed1ng x 2 l\u1ea7n\/ng\u00e0y), \u0111i\u1ec1u tr\u1ecb t\u1ed1i \u0111a 8 tu\u1ea7n.<\/p>\n<p>Li\u1ec1u chung: 150mg\/l\u1ea7n (t\u01b0\u01a1ng \u0111\u01b0\u01a1ng v\u1edbi 1 \u1ed1ng\/l\u1ea7n), ng\u00e0y 2 l\u1ea7n, kh\u00f4ng qu\u00e1 300mg\/ng\u00e0y.<\/p>\n<p>Ch\u01b0a x\u00e1c \u0111\u1ecbnh \u0111\u1ed9 an to\u00e0n cho tr\u1ebb ch\u01b0a \u0111\u1ebfn 12 tu\u1ed5i.<\/p>\n<p><em><strong>Suy th\u1eadn<\/strong><\/em><\/p>\n<p>\u0110\u1ed9 l\u1ecdc c\u1ea7u th\u1eadn 20 \u2013 50 ml\/ph\u00fat: Gi\u1ea3m 50% li\u1ec1u ho\u1eb7c d\u00f9ng 1 \u1ed1ng\/ng\u00e0y<\/p>\n<p>\u0110\u1ed9 l\u1ecdc &lt; 20 ml\/ph\u00fat: Gi\u1ea3m 75% li\u1ec1u, d\u00f9ng 1 \u1ed1ng c\u00e1ch 48 gi\u1edd\/l\u1ea7n.<\/p>\n<p><em><strong>Duy tr\u00ec lo\u00e9t t\u00e1 tr\u00e0ng<\/strong><\/em><\/p>\n<p>ClCr 20 \u2013 50 ml\/ph\u00fat: 1 \u1ed1ng c\u00e1ch 48 gi\u1edd\/l\u1ea7n.<\/p>\n<p>ClCr &lt; 20 ml\/ph\u00fat: 1 \u1ed1ng c\u00e1ch 72 gi\u1edd\/l\u1ea7n.<\/p>\n<p><em><strong>Suy gan n\u1eb7ng:<\/strong><\/em> Gi\u1ea3m li\u1ec1u kho\u1ea3ng 1\/3, \u01b0u ti\u00ean d\u00f9ng vi\u00ean 150mg, \u0111\u1eb7c bi\u1ec7t n\u1ebfu c\u00f3 k\u00e8m suy th\u1eadn.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>Thu\u1ed1c d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng, c\u00f3 th\u1ec3 u\u1ed1ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng th\u1ee9c \u0103n. C\u1ea7n tu\u00e2n th\u1ee7 li\u1ec1u \u0111\u01b0\u1ee3c b\u00e1c s\u0129 k\u00ea, kh\u00f4ng t\u1ef1 \u00fd t\u0103ng ho\u1eb7c gi\u1ea3m li\u1ec1u.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi nizatidin ho\u1eb7c t\u00e1 d\u01b0\u1ee3c n\u00e0o c\u00f3 trong <strong>dung d\u1ecbch u\u1ed1ng Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng<\/strong><\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Khi ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb lo\u00e9t d\u1ea1 d\u00e0y b\u1eb1ng Nitidine, c\u1ea7n ki\u1ec3m tra v\u00e0 lo\u1ea1i tr\u1eeb ung th\u01b0 d\u1ea1 d\u00e0y tr\u01b0\u1edbc, v\u00ec thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m ho\u1eb7c che l\u1ea5p tri\u1ec7u ch\u1ee9ng, khi\u1ebfn vi\u1ec7c ch\u1ea9n \u0111o\u00e1n b\u1ecb ch\u1eadm tr\u1ec5.<\/p>\n<p>C\u00f3 hi\u1ec7n t\u01b0\u1ee3ng m\u1eabn c\u1ea3m ch\u00e9o: ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi thu\u1ed1c kh\u00e1ng H\u2082 kh\u00e1c c\u00f3 th\u1ec3 c\u0169ng ph\u1ea3n \u1ee9ng v\u1edbi nizatidin.<\/p>\n<p>\u1ede b\u1ec7nh nh\u00e2n suy th\u1eadn (ClCr &lt; 50 ml\/ph\u00fat), c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u ho\u1eb7c k\u00e9o d\u00e0i kho\u1ea3ng c\u00e1ch gi\u1eefa c\u00e1c l\u1ea7n d\u00f9ng.<\/p>\n<p>Ng\u01b0\u1eddi suy gan ho\u1eb7c x\u01a1 gan n\u00ean d\u00f9ng li\u1ec1u th\u1ea5p h\u01a1n, theo d\u00f5i ch\u1eb7t ch\u1ebd trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Hi\u1ec7u qu\u1ea3 v\u00e0 \u0111\u1ed9 an to\u00e0n ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ee9ng minh \u1edf tr\u1ebb d\u01b0\u1edbi 12 tu\u1ed5i.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p><em><strong>Th\u01b0\u1eddng g\u1eb7p (ADR &gt;1\/100): <\/strong><\/em>C\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n n\u1ed5i m\u1ea9n, ng\u1ee9a, vi\u00eam da; c\u00e1c tri\u1ec7u ch\u1ee9ng \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p nh\u01b0 ho, ch\u1ea3y n\u01b0\u1edbc m\u0169i, vi\u00eam h\u1ecdng, vi\u00eam xoang; ngo\u00e0i ra \u0111\u00f4i khi \u0111au l\u01b0ng ho\u1eb7c \u0111au ng\u1ef1c<\/p>\n<p><em><strong>\u00cdt g\u1eb7p (1\/1.000 &lt; ADR &lt; 1\/100):<\/strong><\/em>\u00a0M\u00e0y \u0111ay, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a (\u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, t\u00e1o b\u00f3n, kh\u00f4 mi\u1ec7ng, bu\u1ed3n n\u00f4n), nhi\u1ec5m khu\u1ea9n k\u00e8m s\u1ed1t, t\u0103ng acid uric m\u00e1u.<\/p>\n<p><em><strong>Hi\u1ebfm g\u1eb7p (ADR &lt;1\/1000):<\/strong><\/em> C\u00f3 th\u1ec3 bao g\u1ed3m ch\u00f3ng m\u1eb7t, m\u1ec7t m\u1ecfi, m\u1ea5t ng\u1ee7, \u0111au \u0111\u1ea7u; ph\u1ea3n \u1ee9ng tr\u00ean da nh\u01b0 h\u1ed3ng ban \u0111a d\u1ea1ng, r\u1ee5ng t\u00f3c, ho\u1ea1i t\u1eed bi\u1ec3u b\u00ec; r\u1ed1i lo\u1ea1n huy\u1ebft h\u1ecdc, ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn (s\u1ed1c ph\u1ea3n v\u1ec7, ph\u00f9 m\u1ea1ch, co th\u1eaft ph\u1ebf qu\u1ea3n, ph\u00f9 thanh qu\u1ea3n); r\u1ed1i lo\u1ea1n gan m\u1eadt (v\u00e0ng da, \u1ee9 m\u1eadt, t\u0103ng men gan); r\u1ed1i lo\u1ea1n th\u1ea7n kinh \u2013 t\u00e2m th\u1ea7n (b\u1ed3n ch\u1ed3n, \u1ea3o gi\u00e1c, l\u00fa l\u1eabn); \u1ea3nh h\u01b0\u1edfng n\u1ed9i ti\u1ebft (gi\u1ea3m ham mu\u1ed1n t\u00ecnh d\u1ee5c, v\u00fa to \u1edf nam gi\u1edbi); \u0111au c\u01a1 kh\u1edbp; r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c.<\/p>\n<p><em><strong>X\u1eed tr\u00ed:<\/strong><\/em> H\u1ea7u h\u1ebft t\u00e1c d\u1ee5ng ph\u1ee5 nh\u1eb9 v\u00e0 tho\u00e1ng qua, th\u01b0\u1eddng bi\u1ebfn m\u1ea5t khi ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb. N\u1ebfu xu\u1ea5t hi\u1ec7n ph\u1ea3n \u1ee9ng n\u1eb7ng, c\u1ea7n ng\u01b0ng thu\u1ed1c v\u00e0 b\u00e1o cho b\u00e1c s\u0129.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Thu\u1ed1c l\u00e1: H\u00fat thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf ti\u1ebft acid d\u1ecbch v\u1ecb v\u00e0o ban \u0111\u00eam c\u1ee7a c\u00e1c thu\u1ed1c kh\u00e1ng th\u1ee5 th\u1ec3 H\u2082, n\u00ean khuy\u00ean ng\u01b0\u1eddi b\u1ec7nh ng\u1eebng ho\u1eb7c \u00edt nh\u1ea5t kh\u00f4ng h\u00fat thu\u1ed1c sau khi d\u00f9ng li\u1ec1u thu\u1ed1c cu\u1ed1i trong ng\u00e0y.<\/p>\n<p>R\u01b0\u1ee3u: N\u00ean tr\u00e1nh s\u1eed d\u1ee5ng \u0111\u1ed3 u\u1ed1ng ch\u1ee9a c\u1ed3n trong th\u1eddi gian d\u00f9ng thu\u1ed1c.<\/p>\n<p>Cytochrom P450: Kh\u00e1c v\u1edbi cimetidin, nizatidin kh\u00f4ng \u1ee9c ch\u1ebf h\u1ec7 enzym n\u00e0y n\u00ean \u00edt \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn chuy\u1ec3n h\u00f3a thu\u1ed1c kh\u00e1c. Tuy nhi\u00ean, vi\u1ec7c l\u00e0m t\u0103ng pH d\u1ea1 d\u00e0y c\u00f3 th\u1ec3 t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn kh\u1ea3 n\u0103ng h\u1ea5p thu c\u1ee7a m\u1ed9t s\u1ed1 thu\u1ed1c.<\/p>\n<p>Thu\u1ed1c kh\u00e1ng acid: Khi d\u00f9ng \u0111\u1ed3ng th\u1eddi c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m h\u1ea5p thu nizatidin. Khuy\u00ean b\u1ec7nh nh\u00e2n kh\u00f4ng u\u1ed1ng thu\u1ed1c kh\u00e1ng acid trong v\u00f2ng 1 gi\u1edd sau khi d\u00f9ng thu\u1ed1c kh\u00e1ng th\u1ee5 th\u1ec3 H\u2082.<\/p>\n<p>Thu\u1ed1c g\u00e2y suy t\u1ee7y (chloramphenicol, cyclophosphamid\u2026): D\u00f9ng chung c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh ho\u1eb7c r\u1ed1i lo\u1ea1n t\u1ea1o m\u00e1u.<\/p>\n<p>Itraconazol, ketoconazol: S\u1ef1 h\u1ea5p thu c\u1ee7a hai thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 gi\u1ea3m r\u00f5 r\u1ec7t khi d\u00f9ng c\u00f9ng kh\u00e1ng th\u1ee5 th\u1ec3 H\u2082 do t\u0103ng pH d\u1ea1 d\u00e0y, n\u00ean u\u1ed1ng kh\u00e1ng H\u2082 \u00edt nh\u1ea5t 2 gi\u1edd sau khi d\u00f9ng c\u00e1c thu\u1ed1c n\u00e0y.<\/p>\n<p>Salicylat (acid acetylsalicylic li\u1ec1u cao): C\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 salicylat trong m\u00e1u khi d\u00f9ng chung.<\/p>\n<p>Sucralfat: L\u00e0m gi\u1ea3m h\u1ea5p thu kh\u00e1ng th\u1ee5 th\u1ec3 H\u2082, do \u0111\u00f3 hai thu\u1ed1c n\u00ean d\u00f9ng c\u00e1ch nhau \u00edt nh\u1ea5t 2 gi\u1edd.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef mang thai: Nizatidin c\u00f3 th\u1ec3 \u0111i qua nhau thai. Do c\u00e1c d\u1eef li\u1ec7u nghi\u00ean c\u1ee9u tr\u00ean ph\u1ee5 n\u1eef mang thai ch\u01b0a \u0111\u1ea7y \u0111\u1ee7, thu\u1ed1c ch\u1ec9 n\u00ean \u0111\u01b0\u1ee3c d\u00f9ng khi th\u1ef1c s\u1ef1 c\u1ea7n thi\u1ebft v\u00e0 ph\u1ea3i c\u00f3 ch\u1ec9 \u0111\u1ecbnh, theo d\u00f5i c\u1ee7a b\u00e1c s\u0129.<\/p>\n<p>Ph\u1ee5 n\u1eef cho con b\u00fa: Thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9, ti\u1ec1m \u1ea9n nguy c\u01a1 g\u00e2y t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n cho tr\u1ebb b\u00fa m\u1eb9. Ng\u01b0\u1eddi m\u1eb9 \u0111ang d\u00f9ng thu\u1ed1c n\u00ean t\u1ea1m ng\u1eebng cho con b\u00fa ho\u1eb7c c\u00e2n nh\u1eafc ng\u1eebng d\u00f9ng thu\u1ed1c trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c ho\u1eb7c bu\u1ed3n ng\u1ee7 c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 t\u1eadp trung v\u00e0 ph\u1ea3n x\u1ea1.<\/p>\n<p>Ng\u01b0\u1eddi \u0111ang s\u1eed d\u1ee5ng thu\u1ed1c c\u1ea7n tr\u00e1nh \u0111i\u1ec1u khi\u1ec3n xe c\u01a1 gi\u1edbi ho\u1eb7c l\u00e0m vi\u1ec7c tr\u00ean cao, v\u1eadn h\u00e0nh m\u00e1y m\u00f3c n\u1eb7ng n\u1ebfu xu\u1ea5t hi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng n\u00e0y.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p b\u1eaft bu\u1ed9c ph\u1ea3i l\u00e0m vi\u1ec7c, c\u1ea7n tham kh\u1ea3o \u00fd ki\u1ebfn b\u00e1c s\u0129 \u0111\u1ec3 c\u00f3 bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba ph\u00f9 h\u1ee3p.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tri\u1ec7u ch\u1ee9ng: D\u1eef li\u1ec7u v\u1ec1 qu\u00e1 li\u1ec1u \u1edf ng\u01b0\u1eddi c\u00f2n h\u1ea1n ch\u1ebf. \u1ede \u0111\u1ed9ng v\u1eadt, khi d\u00f9ng li\u1ec1u cao ho\u1ea1t ch\u1ea5t Nitidine c\u00f3 th\u1ec3 g\u1eb7p c\u00e1c bi\u1ec3u hi\u1ec7n ki\u1ec3u cholinergic nh\u01b0 ch\u1ea3y n\u01b0\u1edbc m\u1eaft, ti\u1ebft n\u01b0\u1edbc b\u1ecdt, n\u00f4n, co \u0111\u1ed3ng t\u1eed, ti\u00eau ch\u1ea3y.<\/p>\n<p><em><strong>X\u1eed tr\u00ed:<\/strong><\/em><\/p>\n<p>Hi\u1ec7n ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c ri\u00eang bi\u1ec7t cho nizatidin..<\/p>\n<p>Gi\u1ea3m h\u1ea5p thu thu\u1ed1c Nitidine b\u1eb1ng nhi\u1ec1u c\u00e1ch kh\u00e1c nhau nh\u01b0 n\u00f4n, d\u00f9ng than ho\u1ea1t, r\u1eeda d\u1ea1 d\u00e0y<\/p>\n<p>Khi x\u1ea3y ra c\u01a1n co gi\u1eadt, c\u00f3 th\u1ec3 x\u1eed tr\u00ed b\u1eb1ng c\u00e1ch ti\u00eam t\u0129nh m\u1ea1ch diazepam.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p nh\u1ecbp tim gi\u1ea3m qu\u00e1 m\u1ee9c, c\u1ea7n can thi\u1ec7p b\u1eb1ng atropin.<\/p>\n<p>N\u1ebfu xu\u1ea5t hi\u1ec7n r\u1ed1i lo\u1ea1n nh\u1ecbp th\u1ea5t, c\u00f3 th\u1ec3 c\u00e2n nh\u1eafc s\u1eed d\u1ee5ng lidocain \u0111\u1ec3 ki\u1ec3m so\u00e1t.<\/p>\n<p>C\u00f3 th\u1ec3 th\u1ea9m ph\u00e2n m\u00e1u<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p><span style=\"font-size: 14.4px;\">Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng v\u1edbi Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng nh\u01b0:<\/span><\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/ranilex\/\">Ranilex<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Ranitidin Hydroclorid 31,5mg v\u00e0 c\u00e1c mu\u1ed1i magnesi, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n Korea United Pharm. Int\u2019 l, gi\u1ea3m nguy c\u01a1 vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y, t\u00e1 tr\u00e0ng<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/albis\/\">Albis<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Ranitidin Hydroclorid, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Daewoong Pharm Co., Ltd \u2013 H\u00c0N QU\u1ed0C, gi\u1ea3m nguy c\u01a1 vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y, t\u00e1 tr\u00e0ng<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/To-huong-dan-su-dung-Nitidine-15mg-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 26 th\u00e1ng 9 n\u0103m 2025<\/li>\n<li>Lu Q, Luo S, Shi Z, Yu M, Guo W, Li C (2022). Nitidine chloride, a benzophenanthridine alkaloid from Zanthoxylum nitidum (Roxb.) DC., exerts multiple beneficial properties, especially in tumors and inflammation-related diseases. Front Pharmacol. Truy c\u1eadp ng\u00e0y 26 th\u00e1ng 9 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9729779\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9729779\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Nitidine 15mg\/ml Ph\u01b0\u01a1ng \u0110\u00f4ng l\u00e0 thu\u1ed1c nh\u00f3m kh\u00e1ng th\u1ee5 th\u1ec3 H\u2082 histamin d\u00f9ng \u0111i\u1ec1u tr\u1ecb lo\u00e9t d\u1ea1 d\u00e0y, t\u00e1 tr\u00e0ng; tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y, th\u1ef1c qu\u1ea3n v\u00e0 c\u00e1c b\u1ec7nh l\u00fd do t\u0103ng ti\u1ebft acid d\u1ecbch v\u1ecb<\/p>\n","protected":false},"author":1,"featured_media":141268,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-141249","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/141249","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=141249"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/141268"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=141249"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=141249"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=141249"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}