{"id":141100,"date":"2025-09-29T08:02:36","date_gmt":"2025-09-29T01:02:36","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=141100"},"modified":"2025-09-29T08:06:34","modified_gmt":"2025-09-29T01:06:34","slug":"atorpa-e-40-10","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/atorpa-e-40-10\/","title":{"rendered":"Atorpa-E 40\/10"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, <\/strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Atorpa- E 40\/10<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c Apimed, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110200000 (S\u0110K c\u0169: VD-32756-19).<\/strong><\/p>\n

Atorpa- E 40\/10 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n

Th\u00e0nh ph\u1ea7n<\/h3>\n

Thu\u1ed1c Atorpa- E 40\/10<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n

    \n
  • Atorvastatin (d\u01b0\u1edbi d\u1ea1ng atorvastatin calci trihydrat) 40mg;<\/li>\n
  • Ezetimibe 10mg<\/li>\n<\/ul>\n

    D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n

    Tr\u00ecnh b\u00e0y<\/h3>\n

    S\u0110K: 893110200000 (S\u0110K c\u0169: VD-32756-19)<\/p>\n

    Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n

    Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n

    H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n

    T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Atorpa- E 40\/10<\/h2>\n

    C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n

    Atorvastatin thu\u1ed9c nh\u00f3m thu\u1ed1c statin, c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc v\u00e0 c\u1ea1nh tranh v\u1edbi enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA l\u00e0 ch\u1ea5t x\u00fac t\u00e1c gi\u00fap chuy\u1ec3n h\u00f3a t\u1ea1o th\u00e0nh mevalonat, cholesterol \u1edf gan. Do \u0111\u00f3, Atorvastatin \u1ee9c ch\u1ebf HMG-CoA gi\u00fap gi\u1ea3m t\u1ed5ng h\u1ee3p cholesterol, gi\u1ea3m n\u1ed3ng \u0111\u1ed9 cholesterol to\u00e0n ph\u1ea7n, gi\u1ea3m cholesterol x\u1ea5u, t\u0103ng cholesterol t\u1ed1t; gi\u00fap ph\u00f2ng ng\u1eeba x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch.<\/p>\n

    Ezetimibe c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf s\u1ef1 h\u1ea5p thu cholesterol, gi\u1ea3m v\u1eadn chuy\u1ec3n cholesterol t\u1eeb ru\u1ed9t non \u0111\u1ebfn gan, k\u00edch th\u00edch qu\u00e1 tr\u00ecnh th\u1ea3i tr\u1eeb cholesterol kh\u1ecfi m\u00e1u, gi\u1ea3m d\u1ef1 tr\u1eef cholesterol \u1edf gan, gi\u1ea3m n\u1ed3ng \u0111\u1ed9 cholesterol to\u00e0n ph\u1ea7n, t\u0103ng HDL-C.<\/p>\n

    \u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n\n\n\n\n\n\n\n
    <\/td>\nAtorvastatin<\/td>\nEzetimibe<\/td>\n<\/tr>\n
    H\u1ea5p thu<\/td>\nAtorvastatin h\u1ea5p thu nhanh ch\u00f3ng khi s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng, n\u1ed3ng \u0111\u1ed9 \u0111\u1ea1t \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau kho\u1ea3ng 1-2 gi\u1edd, sinh kh\u1ea3 d\u1ee5ng kho\u1ea3ng 95-99%, sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i kho\u1ea3ng 12% do chuy\u1ec3n h\u00f3a ban \u0111\u1ea7u \u1edf gan<\/td>\nEzetimibe h\u1ea5p thu nhanh ch\u00f3ng khi s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng, n\u1ed3ng \u0111\u1ed9 \u0111\u1ea1t \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau kho\u1ea3ng 1-2 gi\u1edd. Hi\u1ec7n ch\u01b0a x\u00e1c \u0111\u1ecbnh sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i c\u1ee7a thu\u1ed1c.<\/td>\n<\/tr>\n
    Ph\u00e2n b\u1ed1<\/td>\nTh\u1ec3 t\u00edch ph\u00e2n b\u1ed1 kho\u1ea3ng 381L, t\u1ef7 l\u1ec7 li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng tr\u00ean 98%<\/td>\nT\u1ef7 l\u1ec7 li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 99,7%<\/td>\n<\/tr>\n
    Chuy\u1ec3n h\u00f3a<\/td>\nAtorvastatin chuy\u1ec3n h\u00f3a ch\u00ednh t\u1ea1i gan, t\u1ea1o th\u00e0nh ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh (> 70%) v\u00e0 kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh<\/td>\nEzetimibe chuy\u1ec3n h\u00f3a ch\u00ednh t\u1ea1i gan v\u00e0 ru\u1ed9t non<\/td>\n<\/tr>\n
    Th\u1ea3i tr\u1eeb<\/td>\nAtorvastatin th\u1ea3i tr\u1eeb qua m\u1eadt, th\u1eddi gian b\u00e1n th\u1ea3i trung b\u00ecnh kho\u1ea3ng 14 gi\u1edd.<\/td>\nEzetimibe th\u1ea3i tr\u1eeb qua ph\u00e2n v\u00e0 n\u01b0\u1edbc ti\u1ec3u<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    Thu\u1ed1c Atorpa- E 40\/10 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n

    Thu\u1ed1c <\/strong>Atorpa- E 40\/10<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong ph\u00f2ng ng\u1eeba c\u00e1c b\u1ec7nh l\u00fd tim m\u1ea1ch v\u00e0 \u0111i\u1ec1u tr\u1ecb t\u00ecnh tr\u1ea1ng t\u0103ng cholesterol m\u00e1u.<\/p>\n

    \"Atorpa-
    Atorpa- E 40\/10 \u0111i\u1ec1u tr\u1ecb t\u0103ng cholesterol m\u00e1u, ph\u00f2ng ng\u1eeba b\u1ec7nh tim m\u1ea1ch<\/figcaption><\/figure>\n

    Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Atorpa- E 40\/10<\/h2>\n

    Li\u1ec1u d\u00f9ng<\/h3>\n