{"id":140397,"date":"2025-09-20T23:57:56","date_gmt":"2025-09-20T16:57:56","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=140397"},"modified":"2025-09-21T00:00:47","modified_gmt":"2025-09-20T17:00:47","slug":"coaprovel-150mg-12-5mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/coaprovel-150mg-12-5mg\/","title":{"rendered":"Coaprovel 150mg\/12.5mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <a href=\"https:\/\/vnras.com\/drug\/\">d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Coaprovel 150mg\/12.5mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Sanofi Winthrop Industrie c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-16721-13<\/strong><\/p>\n<h2>Coaprovel 150mg\/12.5mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ng Coaprovel 150mg\/12.5mg<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Irbesartan:&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;150mg<\/li>\n<li>Hydrochlorothiazid:&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;12,5mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: lactose monohydrate, microcrystalline cellulose, natri croscarmellose, hypromellose, silicon dioxide, magnesium stearate, titanium dioxide, macrogol 3000, oxide s\u1eaft \u0111\u1ecf, oxide s\u1eaft v\u00e0ng, s\u00e1p carnauba.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-16721-13<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 2 v\u1ec9 x 14 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Ph\u00e1p<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Coaprovel 150mg\/12.5mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Irbesartan: t\u00e1c \u0111\u1ed9ng l\u00ean h\u1ec7 renin-angiotensin b\u1eb1ng c\u00e1ch phong t\u1ecfa th\u1ee5 th\u1ec3 AT1 t\u1eeb \u0111\u00f3 ng\u0103n ch\u1eb7n angiotensin II g\u1eafn v\u00e0o th\u1ee5 th\u1ec3, irbesartan gi\u00fap gi\u00e3n m\u1ea1ch v\u00e0 l\u00e0m gi\u1ea3m huy\u1ebft \u00e1p. \u0110\u1ed3ng th\u1eddi, thu\u1ed1c c\u00f2n l\u00e0m t\u0103ng ho\u1ea1t t\u00ednh renin huy\u1ebft t\u01b0\u01a1ng, t\u0103ng n\u1ed3ng \u0111\u1ed9 angiotensin II nh\u01b0ng gi\u1ea3m aldosteron huy\u1ebft t\u01b0\u01a1ng, t\u1eeb \u0111\u00f3 h\u1ed7 tr\u1ee3 hi\u1ec7u qu\u1ea3 trong ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p.<\/p>\n<p>Hydrochlorothiazid: l\u00e0 thu\u1ed1c l\u1ee3i ti\u1ec3u nh\u00f3m thiazid, c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf t\u00e1i h\u1ea5p thu natri v\u00e0 clor t\u1ea1i \u1ed1ng th\u1eadn, d\u1eabn \u0111\u1ebfn t\u0103ng th\u1ea3i tr\u1eeb n\u01b0\u1edbc v\u00e0 mu\u1ed1i. Vi\u1ec7c gi\u1ea3m th\u1ec3 t\u00edch huy\u1ebft t\u01b0\u01a1ng v\u00e0 thay \u0111\u1ed5i c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i g\u00f3p ph\u1ea7n h\u1ea1 \u00e1p. Khi ph\u1ed1i h\u1ee3p c\u00f9ng irbesartan, s\u1ef1 m\u1ea5t kali do hydrochlorothiazid \u0111\u01b0\u1ee3c b\u00f9 tr\u1eeb, nh\u1edd \u0111\u00f3 t\u0103ng hi\u1ec7u qu\u1ea3 v\u00e0 \u0111\u1ed9 an to\u00e0n.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>S\u1ef1 ph\u1ed1i h\u1ee3p irbesartan v\u00e0 hydrochlorothiazid kh\u00f4ng l\u00e0m thay \u0111\u1ed5i \u0111\u1eb7c t\u00ednh d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a t\u1eebng th\u00e0nh ph\u1ea7n.<\/p>\n<p>Irbesartan: h\u1ea5p thu t\u1ed1t qua \u0111\u01b0\u1eddng u\u1ed1ng, sinh kh\u1ea3 d\u1ee5ng 60\u201380%, \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau 1,5\u20132 gi\u1edd, g\u1eafn protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 96%. Th\u1eddi gian b\u00e1n th\u1ea3i 11\u201315 gi\u1edd, \u0111\u1ea1t tr\u1ea1ng th\u00e1i \u1ed5n \u0111\u1ecbnh sau 3 ng\u00e0y d\u00f9ng li\u1ec1u m\u1ed9t l\u1ea7n m\u1ed7i ng\u00e0y. Thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu \u1edf gan v\u00e0 \u0111\u00e0o th\u1ea3i m\u1ed9t ph\u1ea7n nh\u1ecf qua th\u1eadn d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i.<\/p>\n<p>Hydrochlorothiazid: sinh kh\u1ea3 d\u1ee5ng 50\u201380%, \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a sau 1\u20132,5 gi\u1edd, g\u1eafn protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 68%, th\u1eddi gian b\u00e1n th\u1ea3i trung b\u00ecnh 5\u201315 gi\u1edd. Kh\u00f4ng chuy\u1ec3n h\u00f3a t\u1ea1i gan, th\u1ea3i tr\u1eeb nhanh qua th\u1eadn, kho\u1ea3ng 61% li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i nguy\u00ean d\u1ea1ng trong v\u00f2ng 24 gi\u1edd.<\/p>\n<h2>Thu\u1ed1c Coaprovel 150mg\/12.5mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Coaprovel 150mg\/12.5mg \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p nguy\u00ean ph\u00e1t \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u00e0 vi\u1ec7c d\u00f9ng \u0111\u01a1n tr\u1ecb li\u1ec7u b\u1eb1ng irbesartan ho\u1eb7c hydrochlorothiazid kh\u00f4ng mang l\u1ea1i hi\u1ec7u qu\u1ea3 ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p \u0111\u1ea7y \u0111\u1ee7.<\/p>\n<figure id=\"attachment_140411\" aria-describedby=\"caption-attachment-140411\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-140411\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Coaprovel-150mg12.5mg.jpg\" alt=\"Coaprovel 150mg\/12.5mg\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Coaprovel-150mg12.5mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Coaprovel-150mg12.5mg-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Coaprovel-150mg12.5mg-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Coaprovel-150mg12.5mg-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Coaprovel-150mg12.5mg-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-140411\" class=\"wp-caption-text\">Thu\u1ed1c Coaprovel 150mg\/12.5mg c\u00f3 t\u00e1c d\u1ee5ng gi\u00fap ki\u1ec3m so\u00e1t t\u0103ng huy\u1ebft \u00e1p<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Li\u1ec1u th\u00f4ng th\u01b0\u1eddng: 1\u20132 vi\u00ean m\u1ed7i ng\u00e0y.<\/p>\n<p>B\u00e1c s\u0129 s\u1ebd quy\u1ebft \u0111\u1ecbnh vi\u1ec7c chuy\u1ec3n \u0111\u1ed5i t\u1eeb c\u00e1c thu\u1ed1c h\u1ea1 \u00e1p \u0111ang d\u00f9ng sang Coaprovel v\u00e0 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u ph\u00f9 h\u1ee3p cho t\u1eebng b\u1ec7nh nh\u00e2n.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>U\u1ed1ng nguy\u00ean vi\u00ean n\u00e9n Coaprovel 150mg\/12.5mg v\u1edbi n\u01b0\u1edbc, c\u00f3 th\u1ec3 d\u00f9ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng b\u1eefa \u0103n.<\/p>\n<p>N\u00ean u\u1ed1ng Coaprovel v\u00e0o c\u00f9ng m\u1ed9t th\u1eddi \u0111i\u1ec3m c\u1ed1 \u0111\u1ecbnh trong ng\u00e0y \u0111\u1ec3 \u0111\u1ea1t hi\u1ec7u qu\u1ea3 t\u1ed1i \u01b0u.<\/p>\n<p>Hi\u1ec7u qu\u1ea3 h\u1ea1 \u00e1p r\u00f5 r\u1ec7t nh\u1ea5t sau 6\u20138 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Coaprovel 150mg\/12.5mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi m\u1eabn c\u1ea3m v\u1edbi irbesartan, hydrochlorothiazid, d\u1eabn xu\u1ea5t sulfonamid ho\u1eb7c b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>Ph\u1ee5 n\u1eef mang thai t\u1eeb th\u00e1ng th\u1ee9 4 tr\u1edf \u0111i (t\u1ed1t nh\u1ea5t tr\u00e1nh d\u00f9ng ngay t\u1eeb khi ph\u00e1t hi\u1ec7n c\u00f3 thai).<\/p>\n<p>B\u1ec7nh nh\u00e2n suy gan ho\u1eb7c suy th\u1eadn n\u1eb7ng, v\u00f4 ni\u1ec7u.<\/p>\n<p>Ng\u01b0\u1eddi c\u00f3 r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i m\u1ea1n t\u00ednh: t\u0103ng calci m\u00e1u ho\u1eb7c h\u1ea1 kali m\u00e1u k\u00e9o d\u00e0i.<\/p>\n<p>Tr\u1ebb em &lt;18 tu\u1ed5i<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>B\u00e1o v\u1edbi b\u00e1c s\u0129 n\u1ebfu \u0111ang g\u1eb7p t\u00ecnh tr\u1ea1ng ti\u00eau ch\u1ea3y, n\u00f4n \u00f3i nhi\u1ec1u, c\u00f3 b\u1ec7nh tim, th\u1eadn (bao g\u1ed3m gh\u00e9p th\u1eadn), gan, \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, lupus ban \u0111\u1ecf h\u1ec7 th\u1ed1ng, hay t\u0103ng aldosteron nguy\u00ean ph\u00e1t.<\/p>\n<p>Ng\u01b0\u1eddi \u0103n ki\u00eang mu\u1ed1i c\u1ea7n \u0111\u1eb7c bi\u1ec7t l\u01b0u \u00fd.<\/p>\n<p>C\u1ea7n theo d\u00f5i khi c\u00f3 c\u00e1c d\u1ea5u hi\u1ec7u nh\u01b0 kh\u00e1t nhi\u1ec1u, kh\u00f4 mi\u1ec7ng, m\u1ec7t m\u1ecfi, bu\u1ed3n ng\u1ee7, co c\u1ee9ng c\u01a1, bu\u1ed3n n\u00f4n, n\u00f4n, tim \u0111\u1eadp nhanh \u2013 \u0111\u00e2y c\u00f3 th\u1ec3 l\u00e0 d\u1ea5u hi\u1ec7u m\u1ea5t c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i do hydrochlorothiazid.<\/p>\n<p>\u0110\u00e3 t\u1eebng c\u00f3 ph\u1ea3n \u1ee9ng nh\u1ea1y c\u1ea3m da v\u1edbi \u00e1nh s\u00e1ng th\u00ec c\u1ea7n c\u1ea9n tr\u1ecdng khi d\u00f9ng thu\u1ed1c.<\/p>\n<p>N\u1ebfu s\u1eafp ph\u1eabu thu\u1eadt ho\u1eb7c g\u00e2y m\u00ea, c\u1ea7n th\u00f4ng b\u00e1o cho b\u00e1c s\u0129.<\/p>\n<p>Hydrochlorothiazid trong thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m x\u00e9t nghi\u1ec7m doping cho k\u1ebft qu\u1ea3 d\u01b0\u01a1ng t\u00ednh.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>C\u00f3 th\u1ec3 g\u00e2y d\u1ecb \u1ee9ng: ph\u00e1t ban, m\u1ec1 \u0111ay, ph\u00f9 m\u1eb7t\/m\u00f4i\/l\u01b0\u1ee1i, kh\u00f3 th\u1edf \u2192 c\u1ea7n ng\u1eebng thu\u1ed1c ngay.<\/p>\n<p>Th\u01b0\u1eddng g\u1eb7p: bu\u1ed3n n\u00f4n, n\u00f4n, ch\u00f3ng m\u1eb7t, m\u1ec7t, r\u1ed1i lo\u1ea1n ti\u1ec3u ti\u1ec7n, b\u1ea5t th\u01b0\u1eddng ch\u1ee9c n\u0103ng th\u1eadn, ti\u00eau c\u01a1 v\u00e2n.<\/p>\n<p>\u00cdt g\u1eb7p: ti\u00eau ch\u1ea3y, h\u1ea1 huy\u1ebft \u00e1p, ng\u1ea5t, tim \u0111\u1eadp nhanh, \u0111\u1ecf b\u1eebng m\u1eb7t, ph\u00f9, r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng, h\u1ea1 natri\/kali m\u00e1u.<\/p>\n<p>\u0110\u00e3 ghi nh\u1eadn: \u0111au \u0111\u1ea7u, \u00f9 tai, ho, thay \u0111\u1ed5i v\u1ecb gi\u00e1c, kh\u00f3 ti\u00eau, \u0111au c\u01a1 \u2013 kh\u1edbp, r\u1ed1i lo\u1ea1n gan th\u1eadn, v\u00e0ng da, ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn.<\/p>\n<p>Irbesartan: c\u00f3 th\u1ec3 g\u00e2y \u0111au ng\u1ef1c.<\/p>\n<p>Hydrochlorothiazid: g\u00e2y ch\u00e1n \u0103n, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a, vi\u00eam t\u1ee5y, thay \u0111\u1ed5i t\u00e2m tr\u1ea1ng, r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c, thi\u1ebfu m\u00e1u, vi\u00eam ph\u1ed5i, ph\u1ea3n \u1ee9ng da n\u1eb7ng, t\u0103ng \u0111\u01b0\u1eddng huy\u1ebft\/m\u1ee1 m\u00e1u\/acid uric \u2192 nguy c\u01a1 gout.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>T\u0103ng t\u00e1c d\u1ee5ng h\u1ea1 \u00e1p khi d\u00f9ng chung thu\u1ed1c h\u1ea1 huy\u1ebft \u00e1p kh\u00e1c.<\/p>\n<p>Lithium: t\u0103ng \u0111\u1ed9c t\u00ednh, c\u1ea7n theo d\u00f5i n\u1ed3ng \u0111\u1ed9 m\u00e1u.<\/p>\n<p>Thu\u1ed1c \u1ea3nh h\u01b0\u1edfng kali (b\u1ed5 sung kali, l\u1ee3i ti\u1ec3u gi\u1eef kali, heparin&#8230;): nguy c\u01a1 t\u0103ng kali m\u00e1u.<\/p>\n<p>Digitalis, thu\u1ed1c ch\u1ed1ng lo\u1ea1n nh\u1ecbp: r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i, t\u0103ng nguy c\u01a1 lo\u1ea1n nh\u1ecbp.<\/p>\n<p>NSAID: c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 h\u1ea1 \u00e1p.<\/p>\n<p>R\u01b0\u1ee3u d\u00f9ng c\u00f9ng Hydrochlorothiazid g\u00e2y t\u1ee5t huy\u1ebft \u00e1p t\u01b0 th\u1ebf<\/p>\n<p>Thu\u1ed1c tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng d\u00f9ng c\u00f9ng Hydrochlorothiazid c\u1ea7n ch\u1ec9nh li\u1ec1u<\/p>\n<p>Nh\u1ef1a trao \u0111\u1ed5i ion d\u00f9ng c\u00f9ng Hydrochlorothiazid l\u00e0m gi\u1ea3m h\u1ea5p thu.<\/p>\n<p>Corticoid, ACTH d\u00f9ng c\u00f9ng Hydrochlorothiazid l\u00e0m t\u0103ng m\u1ea5t \u0111i\u1ec7n gi\u1ea3i.<\/p>\n<p>Thu\u1ed1c gi\u00e3n c\u01a1 v\u00e2n kh\u00f4ng kh\u1eed c\u1ef1c d\u00f9ng c\u00f9ng Hydrochlorothiazid t\u0103ng t\u00e1c d\u1ee5ng.<\/p>\n<p>Allopurinol d\u00f9ng c\u00f9ng Hydrochlorothiazid l\u00e0m t\u0103ng ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng.<\/p>\n<p>Mu\u1ed1i calci d\u00f9ng c\u00f9ng Hydrochlorothiazid l\u00e0m t\u0103ng calci m\u00e1u.<\/p>\n<p>Thu\u1ed1c tr\u1ecb ung th\u01b0, gi\u1ea3m \u0111au, kh\u00e1ng vi\u00eam, vitamin D, thu\u1ed1c nhu\u1eadn tr\u00e0ng, carbamazepin d\u00f9ng c\u00f9ng Hydrochlorothiazid c\u1ea7n theo d\u00f5i x\u00e9t nghi\u1ec7m.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai c\u1ea7n th\u00f4ng b\u00e1o v\u1edbi b\u00e1c s\u0129 tr\u01b0\u1edbc khi d\u00f9ng thu\u1ed1c. Coaprovel kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o trong giai \u0111o\u1ea1n \u0111\u1ea7u thai k\u1ef3, v\u00e0 tuy\u1ec7t \u0111\u1ed1i ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh khi mang thai t\u1eeb th\u00e1ng th\u1ee9 t\u01b0 tr\u1edf \u0111i do nguy c\u01a1 g\u00e2y h\u1ea1i cho thai nhi. Khi d\u1ef1 \u0111\u1ecbnh c\u00f3 thai ho\u1eb7c \u0111\u00e3 c\u00f3 thai, c\u1ea7n ng\u1eebng Coaprovel v\u00e0 chuy\u1ec3n sang thu\u1ed1c thay th\u1ebf an to\u00e0n h\u01a1n.<\/p>\n<p>Trong th\u1eddi k\u1ef3 cho con b\u00fa, thu\u1ed1c kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng v\u00ec ho\u1ea1t ch\u1ea5t c\u00f3 th\u1ec3 b\u00e0i ti\u1ebft qua s\u1eefa v\u00e0 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn tr\u1ebb nh\u1ecf, \u0111\u1eb7c bi\u1ec7t l\u00e0 tr\u1ebb s\u01a1 sinh ho\u1eb7c sinh non. B\u00e1c s\u0129 s\u1ebd c\u00e2n nh\u1eafc ph\u01b0\u01a1ng \u00e1n \u0111i\u1ec1u tr\u1ecb kh\u00e1c cho c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u chuy\u00ean bi\u1ec7t \u0111\u00e1nh gi\u00e1 t\u00e1c \u0111\u1ed9ng c\u1ee7a Coaprovel l\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe hay \u0111i\u1ec1u khi\u1ec3n m\u00e1y m\u00f3c.<\/p>\n<p>M\u1ed9t s\u1ed1 ng\u01b0\u1eddi c\u00f3 th\u1ec3 g\u1eb7p ch\u00f3ng m\u1eb7t ho\u1eb7c m\u1ec7t m\u1ecfi trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p. N\u1ebfu xu\u1ea5t hi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng n\u00e0y, b\u1ec7nh nh\u00e2n c\u1ea7n tham kh\u1ea3o \u00fd ki\u1ebfn b\u00e1c s\u0129 tr\u01b0\u1edbc khi ti\u1ebfp t\u1ee5c l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh thi\u1ebft b\u1ecb c\u01a1 gi\u1edbi.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Khi u\u1ed1ng qu\u00e1 li\u1ec1u Coaprovel, c\u00e1c bi\u1ec3u hi\u1ec7n th\u01b0\u1eddng g\u1eb7p l\u00e0 t\u1ee5t huy\u1ebft \u00e1p, r\u1ed1i lo\u1ea1n nh\u1ecbp tim, m\u1ea5t n\u01b0\u1edbc v\u00e0 r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i do t\u00e1c d\u1ee5ng l\u1ee3i ti\u1ec3u qu\u00e1 m\u1ee9c c\u1ee7a hydrochlorothiazid. B\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 bu\u1ed3n n\u00f4n, n\u00f4n ho\u1eb7c l\u01a1 m\u01a1.<\/p>\n<p>Vi\u1ec7c x\u1eed tr\u00ed ph\u1ee5 thu\u1ed9c v\u00e0o l\u01b0\u1ee3ng thu\u1ed1c \u0111\u00e3 u\u1ed1ng v\u00e0 t\u00ecnh tr\u1ea1ng l\u00e2m s\u00e0ng. C\u00e1c bi\u1ec7n ph\u00e1p bao g\u1ed3m theo d\u00f5i s\u00e1t, \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng, g\u00e2y n\u00f4n ho\u1eb7c r\u1eeda d\u1ea1 d\u00e0y n\u1ebfu m\u1edbi u\u1ed1ng, c\u00f3 th\u1ec3 d\u00f9ng than ho\u1ea1t \u0111\u1ec3 gi\u1ea3m h\u1ea5p thu thu\u1ed1c.<\/p>\n<p>C\u1ea7n x\u00e9t nghi\u1ec7m th\u01b0\u1eddng xuy\u00ean n\u1ed3ng \u0111\u1ed9 \u0111i\u1ec7n gi\u1ea3i v\u00e0 creatinin m\u00e1u. Trong tr\u01b0\u1eddng h\u1ee3p t\u1ee5t huy\u1ebft \u00e1p, b\u1ec7nh nh\u00e2n n\u00ean n\u1eb1m ng\u1eeda v\u00e0 \u0111\u01b0\u1ee3c b\u00f9 d\u1ecbch, \u0111i\u1ec7n gi\u1ea3i k\u1ecbp th\u1eddi.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Coaprovel 150mg\/12.5mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Coaprovel 150mg\/12.5mg trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Coaprovel 150mg\/12.5mg khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p><span style=\"font-size: 14.4px;\">Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Coaprovel 150mg\/12.5mg nh\u01b0:<\/span><\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/irbeplus-hct-150-12-5\/\">Irbeplus HCT 150\/12.5<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Irbesartan 150mg v\u00e0 Hydrochlorothiazide 12.5mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean doanh Stellapharm, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p ph\u1ed1i h\u1ee3p<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/irbeplus-hct-300-12-5\/\">Irbeplus HCT 300\/12.5<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Irbesartan 300mg v\u00e0 Hydrochlorothiazide 12.5mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean doanh Stellapharm, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p ph\u1ed1i h\u1ee3p<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Coaprovel 150mg\/12.5mg \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7<a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/To-huong-dan-su-dung-Tatanol-Ultra-vnras.pdf\"> t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 20 th\u00e1ng 9 n\u0103m 2025<\/li>\n<li>Bramlage P (2009). Fixed combination of irbesartan and hydrochlorothiazide in the management of hypertension. Vasc Health Risk Manag. Truy c\u1eadp ng\u00e0y 20 th\u00e1ng 9 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2672456\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2672456\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Coaprovel 150mg\/12.5mg c\u00f3 t\u00e1c d\u1ee5ng gi\u00fap ki\u1ec3m so\u00e1t t\u0103ng huy\u1ebft \u00e1p \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh khi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb tr\u01b0\u1edbc \u0111\u00f3 kh\u00f4ng mang l\u1ea1i k\u1ebft qu\u1ea3 ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p t\u1ed1i \u01b0u.<\/p>\n","protected":false},"author":1,"featured_media":140401,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-140397","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/140397","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=140397"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/140401"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=140397"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=140397"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=140397"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}