{"id":140242,"date":"2025-09-28T05:43:42","date_gmt":"2025-09-27T22:43:42","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=140242"},"modified":"2025-09-29T02:40:26","modified_gmt":"2025-09-28T19:40:26","slug":"kirby","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/kirby\/","title":{"rendered":"Kirby"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <\/strong><a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/kirby\/\">Kirby<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty CP D\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110435524.<\/strong><\/p>\n<h2>Kirby l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Thu\u1ed1c Kirby<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li>Erdosteine 300mg<\/li>\n<li>Ph\u1ee5 li\u1ec7u v\u0111<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean nang<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110435524<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 6 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_141917\" aria-describedby=\"caption-attachment-141917\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-141917\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/kirby.jpg\" alt=\"Kirby\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/kirby.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/kirby-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/kirby-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/kirby-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/kirby-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-141917\" class=\"wp-caption-text\">Kirby \u0111i\u1ec1u tr\u1ecb \u0111\u1ee3t c\u1ea5p vi\u00eam ph\u1ebf qu\u1ea3n<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Kirby<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Erdosteine l\u00e0 ch\u1ea5t ti\u00eau nh\u1ea7y gi\u00fap l\u00e0m gi\u1ea3m \u0111\u1ed9 nh\u1edbt c\u1ee7a ch\u1ea5t nh\u1ea7y v\u00e0 \u0111\u1eddm m\u1ee7, gi\u00fap long \u0111\u1eddm hi\u1ec7u qu\u1ea3. \u0110\u00e2y l\u00e0 ti\u1ec1n d\u01b0\u1ee3c, sau khi chuy\u1ec3n h\u00f3a s\u1ebd t\u1ea1o ra nh\u00f3m thiol t\u1ef1 do c\u00f3 ho\u1ea1t t\u00ednh. T\u00e1c d\u1ee5ng ch\u00ednh c\u1ee7a erdosteine l\u00e0 m\u1edf li\u00ean k\u1ebft disulfid trong mucoprotein ph\u1ebf qu\u1ea3n, gi\u00fap ph\u00e1 v\u1ee1 c\u1ea5u tr\u00fac nh\u1ea7y \u0111\u1eb7c, d\u1ec5 d\u00e0ng \u0111\u00e0o th\u1ea3i \u0111\u1eddm ra ngo\u00e0i. Ngo\u00e0i ra, erdosteine c\u00f2n ng\u0103n ch\u1eb7n s\u1ef1 k\u1ebft d\u00ednh c\u1ee7a vi khu\u1ea9n tr\u00ean t\u1ebf b\u00e0o bi\u1ec3u m\u00f4 \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p, c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng oxy h\u00f3a m\u1ea1nh m\u1ebd, b\u1ea3o v\u1ec7 m\u00f4 ph\u1ebf qu\u1ea3n kh\u1ecfi t\u1ed5n th\u01b0\u01a1ng do oxy h\u00f3a.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu:<\/p>\n<p>Erdosteine h\u1ea5p thu nhanh qua \u0111\u01b0\u1eddng u\u1ed1ng v\u00e0 nhanh ch\u00f3ng chuy\u1ec3n h\u00f3a qua gan th\u00e0nh ch\u1ea5t chuy\u1ec3n h\u00f3a ho\u1ea1t t\u00ednh (N-thiodiglycolyl-homocystein &#8211; M1). Sau khi u\u1ed1ng li\u1ec1u 300mg, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng (Cmax) \u0111\u1ea1t kho\u1ea3ng 1,26 \u00b5g\/ml sau kho\u1ea3ng 1,18 gi\u1edd (Tmax). Ch\u1ea5t chuy\u1ec3n h\u00f3a M1 c\u00f3 Cmax cao h\u01a1n v\u00e0 Tmax kho\u1ea3ng 1,48 gi\u1edd.<\/p>\n<p>H\u1ea5p thu kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi th\u1ee9c \u0103n.<\/p>\n<p>Ph\u00e2n b\u1ed1:<\/p>\n<p>Erdosteine t\u1eadp trung ch\u1ee7 y\u1ebfu t\u1ea1i th\u1eadn, x\u01b0\u01a1ng, t\u1ee7y s\u1ed1ng v\u00e0 gan. N\u1ed3ng \u0111\u1ed9 d\u01b0\u1ee3c l\u00fd c\u1ee7a erdosteine v\u00e0 M1 c\u0169ng \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong d\u1ecbch r\u1eeda ph\u1ebf nang, cho th\u1ea5y thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng tr\u1ef1c ti\u1ebfp t\u1ea1i ph\u1ed5i. Erdosteine li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 64,5%.<\/p>\n<p>Th\u1ea3i tr\u1eeb:<\/p>\n<p>Th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a erdosteine v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a M1 l\u1ea7n l\u01b0\u1ee3t l\u00e0 kho\u1ea3ng 1,46 v\u00e0 1,62 gi\u1edd. Thu\u1ed1c ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng M1 v\u00e0 sulphat, ph\u00e2n th\u1ea3i tr\u1eeb r\u1ea5t \u00edt. Kh\u00f4ng c\u00f3 hi\u1ec7n t\u01b0\u1ee3ng t\u00edch l\u0169y khi d\u00f9ng li\u1ec1u cao ho\u1eb7c k\u00e9o d\u00e0i.<\/p>\n<h2>Thu\u1ed1c Kirby tr\u1ecb b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c Kirby 300mg \u0111\u01b0\u1ee3c d\u00f9ng trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb long \u0111\u1eddm.<\/li>\n<li>Gi\u00fap gi\u1ea3m tri\u1ec7u ch\u1ee9ng \u0111\u1ee3t c\u1ea5p c\u1ee7a vi\u00eam ph\u1ebf qu\u1ea3n m\u1ea1n t\u00ednh \u1edf ng\u01b0\u1eddi l\u1edbn.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng-C\u00e1ch d\u00f9ng Kirby<\/h2>\n<h3>Li\u1ec1u d\u00f9ng Kirby<\/h3>\n<p>T\u00f9y theo tr\u01b0\u1eddng h\u1ee3p m\u00e0 \u0111\u01b0\u1ee3c b\u00e1c s\u0129 ch\u1ec9 \u0111\u1ecbnh li\u1ec1u d\u00f9ng kh\u00e1c nhau, d\u01b0\u1edbi \u0111\u00e2y l\u00e0 li\u1ec1u d\u00f9ng tham kh\u1ea3o.<\/p>\n<p>Ng\u01b0\u1eddi l\u1edbn v\u00e0 ng\u01b0\u1eddi cao tu\u1ed5i tr\u00ean 18 tu\u1ed5i: 300mg (1 vi\u00ean) x 2 l\u1ea7n\/ng\u00e0y, d\u00f9ng t\u1ed1i \u0111a 10 ng\u00e0y.<\/p>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p>Thu\u1ed1c Kirby d\u00f9ng \u0111\u1ec3 u\u1ed1ng, u\u1ed1ng v\u1edbi nhi\u1ec1u n\u01b0\u1edbc.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Kirby trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng Kirby cho ng\u01b0\u1eddi m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o trong thu\u1ed1c.<\/p>\n<p>B\u1ec7nh nh\u00e2n b\u1ecb x\u01a1 gan ho\u1eb7c thi\u1ebfu h\u1ee5t enzym cystathionin-synthetase.<\/p>\n<p>Ng\u01b0\u1eddi b\u1ecb lo\u00e9t d\u1ea1 d\u00e0y &#8211; t\u00e1 tr\u00e0ng.<\/p>\n<p>Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng cho b\u1ec7nh nh\u00e2n suy th\u1eadn n\u1eb7ng (Clcr &lt; 25 ml\/ph\u00fat) ho\u1eb7c suy gan n\u1eb7ng do thi\u1ebfu d\u1eef li\u1ec7u.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Ng\u01b0\u1eddi suy gan nh\u1eb9 kh\u00f4ng th\u1ea5y t\u0103ng t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0ng kh\u00f4ng n\u00ean v\u01b0\u1ee3t qu\u00e1 li\u1ec1u 300mg\/ng\u00e0y.<\/p>\n<p>Thu\u1ed1c ch\u1ee9a lactose, b\u1ec7nh nh\u00e2n k\u00e9m dung n\u1ea1p galactose, thi\u1ebfu h\u1ee5t lactase ho\u1eb7c r\u1ed1i lo\u1ea1n h\u1ea5p thu glucose-galactose kh\u00f4ng n\u00ean d\u00f9ng.<\/p>\n<p>\u0110\u1ecdc k\u1ef9 h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng tr\u01b0\u1edbc khi d\u00f9ng.<\/p>\n<p>Kh\u00f4ng d\u00f9ng thu\u1ed1c khi xu\u1ea5t hi\u1ec7n c\u00e1c d\u1ea5u hi\u1ec7u h\u01b0 h\u1ecfng nh\u01b0 \u1ea9m m\u1ed1c, ch\u1ea3y n\u01b0\u1edbc, h\u1ebft h\u1ea1n d\u00f9ng.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5 Kirby<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p (1\/100 \u2264 ADR &lt; 1\/10): \u0110au v\u00f9ng th\u01b0\u1ee3ng v\u1ecb (\u0111au d\u1ea1 d\u00e0y).<\/p>\n<p>\u00cdt g\u1eb7p (1\/1.000 \u2264 ADR &lt; 1\/100): \u0110au \u0111\u1ea7u, c\u1ea3m l\u1ea1nh, kh\u00f3 th\u1edf, thay \u0111\u1ed5i v\u1ecb gi\u00e1c, bu\u1ed3n n\u00f4n, n\u00f4n, ti\u00eau ch\u1ea3y, ph\u00f9 m\u1ea1ch, ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn tr\u00ean da nh\u01b0 m\u00e0y \u0111ay, ban \u0111\u1ecf, ph\u00f9 n\u1ec1, eczema.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u \u0111\u1ea7y \u0111\u1ee7 v\u1ec1 \u0111\u1ed9 an to\u00e0n, kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng trong th\u1eddi k\u1ef3 mang thai v\u00e0 cho con b\u00fa.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Erdosteine c\u00f3 \u1ea3nh h\u01b0\u1edfng nh\u1ecf ho\u1eb7c kh\u00f4ng \u0111\u00e1ng k\u1ec3 do \u0111\u00f3 c\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u v\u1ec1 qu\u00e1 li\u1ec1u c\u1ea5p t\u00ednh. Trong tr\u01b0\u1eddng h\u1ee3p nghi ng\u1edd qu\u00e1 li\u1ec1u, c\u1ea7n \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng, h\u1ed7 tr\u1ee3 t\u00edch c\u1ef1c, c\u00f3 th\u1ec3 r\u1eeda d\u1ea1 d\u00e0y v\u00e0 theo d\u00f5i.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h3>\n<p>C\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c, c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng ho\u1ea1t \u0111\u1ed9ng ho\u1eb7c t\u0103ng nguy c\u01a1 t\u00e1c d\u1ee5ng ph\u1ee5.<\/p>\n<p>C\u1ea7n th\u00f4ng b\u00e1o v\u1edbi b\u00e1c s\u0129 v\u1ec1 c\u00e1c thu\u1ed1c ho\u1eb7c th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng \u0111ang d\u00f9ng.<\/p>\n<p>Kh\u00f4ng t\u1ef1 \u00fd thay \u0111\u1ed5i li\u1ec1u ho\u1eb7c ng\u01b0ng thu\u1ed1c m\u00e0 kh\u00f4ng c\u00f3 ch\u1ec9 \u0111\u1ecbnh.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>N\u01a1i kh\u00f4 m\u00e1t, tr\u00e1nh \u00e1nh s\u00e1ng, nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30\u00b0C.<\/p>\n<p>Tr\u00e1nh xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Kirby nh\u01b0:<\/p>\n<p><a href=\"https:\/\/www.vnras.com\/drug\/elpertone\">Elpertone 300mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Korea Prime Pharma Co., Ltd-H\u00e0n Qu\u1ed1c, c\u00f3 t\u00e1c d\u1ee5ng long \u0111\u1eddm.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p class=\"heading-title\">Multifaceted Beneficial Effects of Erdosteine: More than a Mucolytic Agent, truy c\u1eadp ng\u00e0y 26 th\u00e1ng 09 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33025535\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33025535\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Kirby \u0111\u01b0\u1ee3c nhi\u1ec1u ng\u01b0\u1eddi bi\u1ebft v\u1edbi c\u00f4ng d\u1ee5ng l\u00e0m long \u0111\u1eddm, gi\u00fap gi\u1ea3m tri\u1ec7u ch\u1ee9ng \u0111\u1ee3t c\u1ea5p c\u1ee7a vi\u00eam ph\u1ebf qu\u1ea3n m\u1ea1n t\u00ednh \u1edf ng\u01b0\u1eddi l\u1edbn.<\/p>\n","protected":false},"author":1,"featured_media":141926,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-140242","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/140242","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=140242"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/141926"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=140242"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=140242"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=140242"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}