{"id":139212,"date":"2025-09-19T07:24:56","date_gmt":"2025-09-19T00:24:56","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=139212"},"modified":"2025-09-19T07:45:49","modified_gmt":"2025-09-19T00:45:49","slug":"combizar-50-12-5","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/combizar-50-12-5\/","title":{"rendered":"Combizar 50\/12.5"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, <\/strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Combizar 50\/12,5<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH United International Pharma, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110099724 (S\u0110K c\u0169: VD-28623-17).<\/strong><\/p>\n

Combizar 50\/12,5 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n
Th\u00e0nh ph\u1ea7n<\/h3>\n
Thu\u1ed1c Combizar 50\/12,5<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n: Losartan kali 50mg; Hydrochlorothiazide 12,5mg<\/p>\n
D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n
Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: 893110099724 (S\u0110K c\u0169: VD-28623-17)<\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n
Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n
H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n
T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Combizar 50\/12,5<\/h2>\n\n\n\n\n\n\n\n\n\n
<\/td>\n Losartan kali ((Nh\u00f3m ch\u1eb9n th\u1ee5 th\u1ec3 Angiotensin II)<\/td>\n Hydrochlorothiazide (Nh\u00f3m l\u1ee3i ti\u1ec3u Thiazid)<\/td>\n<\/tr>\n
D\u01b0\u1ee3c l\u1ef1c h\u1ecdc<\/td>\n \u1ee8c ch\u1ebf Angiotensin II g\u1eafn v\u00e0o th\u1ee5 th\u1ec3 AT1, t\u1eeb \u0111\u00f3 l\u00e0m gi\u00e3n m\u1ea1ch, gi\u1ea3m ti\u1ebft Aldosterone, gi\u00fap gi\u1ea3m ho v\u00e0 h\u1ea1 huy\u1ebft \u00e1p.<\/td>\n \u1ee8c ch\u1ebf t\u00e1i h\u1ea5p thu Na+ v\u00e0 Cl- \u1edf \u1ed1ng l\u01b0\u1ee3n xa c\u1ee7a th\u1eadn, gi\u00fap t\u0103ng b\u00e0i ti\u1ebft n\u01b0\u1edbc v\u00e0 c\u00e1c ion, gi\u1ea3m cung l\u01b0\u1ee3ng tim, gi\u1ea3m th\u1ec3 t\u00edch n\u1ed9i m\u1ea1ch, gi\u00fap h\u1ea1 huy\u1ebft \u00e1p<\/td>\n<\/tr>\n
D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/td>\n<\/tr>\n
H\u1ea5p thu<\/td>\n Losartan h\u1ea5p thu t\u1ed1t qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, sinh kh\u1ea3 d\u1ee5ng kho\u1ea3ng 33%<\/td>\n Hydrochlorothiazide h\u1ea5p thu t\u1ed1t qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Sinh kh\u1ea3 d\u1ee5ng t\u1eeb 65 \u0111\u1ebfn 75%<\/td>\n<\/tr>\n
Ph\u00e2n b\u1ed1<\/td>\n T\u1ef7 l\u1ec7 Losartan li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kh\u00e1 cao, kho\u1ea3ng 98%<\/td>\n T\u1ef7 l\u1ec7 Hydrochlorothiazide li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng 40-68%<\/td>\n<\/tr>\n
Chuy\u1ec3n h\u00f3a<\/td>\n Losartan chuy\u1ec3n h\u00f3a ch\u00ednh t\u1ea1i gan, t\u1ea1o th\u00e0nh ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh<\/td>\n Hydrochlorothiazide kh\u00f4ng chuy\u1ec3n h\u00f3a trong c\u01a1 th\u1ec3<\/td>\n<\/tr>\n
Th\u1ea3i tr\u1eeb<\/td>\n Thu\u1ed1c th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 ph\u00e2n<\/p>\n
T \u00bd (Losartan) 1,5-2,5 gi\u1edd<\/p>\n
T \u00bd (ch\u1ea5t chuy\u1ec3n h\u00f3a) 6-9 gi\u1edd<\/td>\n
Thu\u1ed1c th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u<\/p>\n
T \u00bd kho\u1ea3ng 5,6-14,8 gi\u1edd<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Thu\u1ed1c Combizar 50\/12,5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n
Thu\u1ed1c Combizar 50\/12,5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p \u1edf b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng bi\u1ec7n ph\u00e1p \u0111\u01a1n tr\u1ecb li\u1ec7u.<\/p>\n
$\"Combizar$
Combizar 50\/12,5 \u0111i\u1ec1u tr\u1ecb t\u00ecnh tr\u1ea1ng huy\u1ebft \u00e1p cao<\/figcaption><\/figure>\n
Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Combizar 50\/12,5<\/h2>\n
Li\u1ec1u d\u00f9ng<\/h3>\n
Li\u1ec1u kh\u1edfi \u0111\u1ea7u v\u00e0 duy tr\u00ec theo h\u01b0\u1edbng d\u1eabn: s\u1eed d\u1ee5ng 1 vi\u00ean m\u1ed7i ng\u00e0y<\/p>\n
\u1ede nh\u1eefng b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u tr\u1ecb, c\u00f3 th\u1ec3 t\u0103ng 2 vi\u00ean m\u00f5i ng\u00e0y<\/p>\n
C\u00e1ch d\u00f9ng<\/h3>\n
Thu\u1ed1c Combizar 50\/12,5<\/strong> d\u1ea1ng vi\u00ean n\u00e9n bao phim, s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng<\/p>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Combizar 50\/12,5 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n
Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng Combizar 50\/12,5 cho b\u1ec7nh nh\u00e2n m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o trong thu\u1ed1c, b\u1ec7nh nh\u00e2n v\u00f4 ni\u1ec7u v\u00e0 ph\u1ee5 n\u1eef \u0111ang mang thai<\/p>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Combizar 50\/12,5<\/h2>\n
Th\u1eadn tr\u1ecdng<\/h3>\n
\n
Kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng thu\u1ed1c cho b\u1ec7nh nh\u00e2n m\u1ea5t n\u01b0\u1edbc n\u1ed9i m\u1ea1c<\/li>\n
Kh\u00f4ng k\u00ea \u0111\u01a1n Combizar 50\/12,5 cho b\u1ec7nh nh\u00e2n suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn n\u1eb7ng<\/li>\n
Hi\u1ec7u ch\u1ec9nh gi\u1ea3m li\u1ec1u ph\u00f9 h\u1ee3p khi d\u00f9ng thu\u1ed1c cho b\u1ec7nh nh\u00e2n suy gan<\/li>\n
Kh\u00f4ng s\u1eed d\u1ee5ng Combizar 50\/12,5 khi h\u1ebft h\u1ea1n s\u1eed d\u1ee5ng<\/li>\n<\/ul>\n
T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n
M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o khi \u0111i\u1ec1u tr\u1ecb cao huy\u1ebft \u00e1p v\u1edbi Combizar 50\/12,5 bao g\u1ed3m \u0111au b\u1ee5ng, suy nh\u01b0\u1ee3c c\u01a1 th\u1ec3, \u0111au \u0111\u1ea7u, nh\u1ecbp tim nhanh, bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y, ch\u00f3ng m\u1eb7t, vi\u00eam ph\u1ebf qu\u1ea3n, vi\u00eam xoang, \u0111au l\u01b0ng, nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p tr\u00ean, qu\u00e1 m\u1eabn.<\/p>\n
B\u1ec7nh nh\u00e2n c\u1ea7n th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 v\u1ec1 c\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i g\u1eb7p ph\u1ea3i trong giai \u0111o\u1ea1n \u0111i\u1ec1u tr\u1ecb v\u1edbi Combizar 50\/12,5.<\/p>\n
T\u01b0\u01a1ng t\u00e1c<\/h3>\n\n\n\n\n\n\n\n\n\n\n\n\n
Thu\u1ed1c<\/td>\n T\u01b0\u01a1ng t\u00e1c<\/td>\n<\/tr>\n
Rifampicin v\u00e0 Fluconazole<\/td>\n Gi\u1ea3m ho\u1ea1t t\u00ednh c\u1ee7a losartan<\/td>\n<\/tr>\n
Thu\u1ed1c l\u1ee3i ti\u1ec3u gi\u1eef kali<\/p>\n
Thu\u1ed1c b\u1ed5 sung kali<\/td>\n
T\u0103ng kali huy\u1ebft<\/td>\n<\/tr>\n
Phenobarbital<\/td>\n Gi\u1ea3m 20% AUC c\u1ee7a losartan v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a<\/td>\n<\/tr>\n
Cimetidin<\/td>\n T\u0103ng 18% AUC c\u1ee7a losartan<\/td>\n<\/tr>\n
R\u01b0\u1ee3u<\/td>\n T\u0103ng nguy c\u01a1 t\u1ee5t huy\u1ebft \u00e1p<\/td>\n<\/tr>\n
Thu\u1ed1c g\u1eafn acid m\u1eadt cholestyramine v\u00e0 colestipol<\/td>\n Gi\u1ea3m h\u1ea5p thu c\u1ee7a Hydrochlorothiazid<\/td>\n<\/tr>\n
Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng<\/td>\n Hi\u1ec7u ch\u1ec9nh li\u1ec1u t\u00f9y theo n\u1ed3ng \u0111\u1ed9 \u0111\u01b0\u1eddng huy\u1ebft th\u1ef1c t\u1ebf<\/td>\n<\/tr>\n
Corticoid<\/td>\n G\u00e2y h\u1ea1 kali huy\u1ebft<\/td>\n<\/tr>\n
Lithium<\/td>\n T\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a lithi<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n
C\u00e2n nh\u1eafc l\u1ee3i \u00edch v\u00e0 nguy c\u01a1 tr\u01b0\u1edbc khi d\u00f9ng Combizar 50\/12,5 cho b\u00e0 m\u1eb9 cho con b\u00fa; kh\u00f4ng d\u00f9ng cho ph\u1ee5 n\u1eef c\u00f3 thai<\/p>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n
Ch\u01b0a c\u00f3 th\u00f4ng tin v\u1ec1 s\u1ef1 \u1ea3nh h\u01b0\u1edfng c\u1ee7a Combizar 50\/12,5 \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n
S\u1eed d\u1ee5ng qu\u00e1 li\u1ec1u Combizar 50\/12,5 g\u00e2y r\u1ed1i lo\u1ea1n n\u01b0\u1edbc v\u00e0 \u0111i\u1ec7n gi\u1ea3i, nh\u1ecbp tim nhanh, t\u1ee5t huy\u1ebft \u00e1p. B\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3, \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng, c\u00f3 th\u1ec3 d\u00f9ng than ho\u1ea1t ho\u1eb7c g\u00e2y n\u00f4n.<\/p>\n
B\u1ea3o qu\u1ea3n<\/h3>\n
B\u1ea3o qu\u1ea3n Combizar 50\/12,5 \u1edf n\u01a1i c\u00f3 \u0111\u1ed9 \u1ea9m kh\u00f4ng qu\u00e1 70%, nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng, n\u01a1i kh\u00f4 r\u00e1o, s\u1ea1ch s\u1ebd. \u0110\u1ec3 tr\u00e1nh xa t\u1ea7m tay tr\u1ebb em.<\/p>\n
S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n
Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Combizar 50\/12,5 nh\u01b0:<\/p>\n
Colosar-Denk 50\/12.5<\/a> c\u00f3 th\u00e0nh ph\u1ea7n Losartan kali 50mg; Hydrochlorothiazide 12,5mg, s\u1ea3n xu\u1ea5t b\u1edfi Denk Pharma GmbH & Co. KG, \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p.<\/p>\n
Lorista HD 100mg\/25mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n Losartan kali 100mg; Hydrochlorothiazide 25mg, s\u1ea3n xu\u1ea5t b\u1edfi D\u01b0\u1ee3c ph\u1ea9m Krka, \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p \u1edf b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng \u0111\u01a1n tr\u1ecb li\u1ec7u.<\/p>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n
H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Combizar 50\/12,5 do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i file t\u1ea1i \u0111\u00e2y<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"
Thu\u1ed1c Combizar 50\/12,5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p \u1edf b\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng bi\u1ec7n ph\u00e1p \u0111\u01a1n tr\u1ecb li\u1ec7u, s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH United International Pharma<\/p>\n","protected":false},"author":1,"featured_media":139928,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-139212","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/139212","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=139212"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/139928"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=139212"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=139212"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=139212"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

Th\u00e0nh ph\u1ea7n<\/h3>\nThu\u1ed1c Combizar 50\/12,5<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n: Losartan kali 50mg; Hydrochlorothiazide 12,5mg<\/p>\nD\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n

Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Combizar 50\/12,5<\/h2>\n

C\u00e1ch d\u00f9ng<\/h3>\nThu\u1ed1c Combizar 50\/12,5<\/strong> d\u1ea1ng vi\u00ean n\u00e9n bao phim, s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng<\/p>\n

L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Combizar 50\/12,5<\/h2>\n

B\u1ea3o qu\u1ea3n<\/h3>\nB\u1ea3o qu\u1ea3n Combizar 50\/12,5 \u1edf n\u01a1i c\u00f3 \u0111\u1ed9 \u1ea9m kh\u00f4ng qu\u00e1 70%, nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng, n\u01a1i kh\u00f4 r\u00e1o, s\u1ea1ch s\u1ebd. \u0110\u1ec3 tr\u00e1nh xa t\u1ea7m tay tr\u1ebb em.<\/p>\n

Th\u00e0nh ph\u1ea7n<\/h3>\n
Thu\u1ed1c Combizar 50\/12,5<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n: Losartan kali 50mg; Hydrochlorothiazide 12,5mg<\/p>\n
D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n

C\u00e1ch d\u00f9ng<\/h3>\n
Thu\u1ed1c Combizar 50\/12,5<\/strong> d\u1ea1ng vi\u00ean n\u00e9n bao phim, s\u1eed d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng<\/p>\n

B\u1ea3o qu\u1ea3n<\/h3>\n
B\u1ea3o qu\u1ea3n Combizar 50\/12,5 \u1edf n\u01a1i c\u00f3 \u0111\u1ed9 \u1ea9m kh\u00f4ng qu\u00e1 70%, nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng, n\u01a1i kh\u00f4 r\u00e1o, s\u1ea1ch s\u1ebd. \u0110\u1ec3 tr\u00e1nh xa t\u1ea7m tay tr\u1ebb em.<\/p>\n