{"id":138815,"date":"2025-09-15T00:34:34","date_gmt":"2025-09-14T17:34:34","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=138815"},"modified":"2025-09-15T00:38:25","modified_gmt":"2025-09-14T17:38:25","slug":"cledomox-625","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/cledomox-625\/","title":{"rendered":"Cledomox 625"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <a href=\"https:\/\/vnras.com\/drug\/\">d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Cledomox 625 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Medopharm Pvt. Ltd. c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-21116-18<\/strong><\/p>\n<h2>Cledomox 625 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ng Cledomox 625<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Amoxicillin trihydrat BP v\u1edbi h\u00e0m l\u01b0\u1ee3ng t\u01b0\u01a1ng \u1ee9ng Amoxicillin 500mg.<\/li>\n<li>Clavulanic acid 125mg.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: Microcrystalline Cellulose (Avicel pH 112), Magnesium Stearate, Colloidal Silicon Dioxide (Aerosil), Natri Starch Glycolate, HPMC E-5, HPMC E-15, Titanium Dioxide, Polyethylene Glycol 6000 v\u00e0 c\u00e1c t\u00e1 d\u01b0\u1ee3c kh\u00e1c v\u1eeba \u0111\u1ee7.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-21116-18<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 2 v\u1ec9 x 7 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: \u1ea4n \u0110\u1ed9<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Cledomox 625<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Amoxicilin l\u00e0 kh\u00e1ng sinh b\u00e1n t\u1ed5ng h\u1ee3p nh\u00f3m beta-lactam, c\u00f3 kh\u1ea3 n\u0103ng di\u1ec7t khu\u1ea9n b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p th\u00e0nh t\u1ebf b\u00e0o vi khu\u1ea9n. Thu\u1ed1c c\u00f3 ph\u1ed5 t\u00e1c d\u1ee5ng r\u1ed9ng tr\u00ean nhi\u1ec1u vi khu\u1ea9n Gram d\u01b0\u01a1ng v\u00e0 Gram \u00e2m, tuy nhi\u00ean d\u1ec5 b\u1ecb b\u1ea5t ho\u1ea1t b\u1edfi enzym beta-lactamase do m\u1ed9t s\u1ed1 ch\u1ee7ng vi khu\u1ea9n ti\u1ebft ra.<\/p>\n<p>Acid clavulanic l\u00e0 ch\u1ea5t c\u00f3 c\u1ea5u tr\u00fac beta-lactam, \u0111\u01b0\u1ee3c t\u1ea1o th\u00e0nh t\u1eeb qu\u00e1 tr\u00ecnh l\u00ean men <em>Streptomyces clavuligerus.<\/em> D\u00f9 b\u1ea3n th\u00e2n c\u00f3 ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n y\u1ebfu, nh\u01b0ng acid clavulanic c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf m\u1ea1nh beta-lactamase, gi\u00fap b\u1ea3o v\u1ec7 amoxicilin kh\u1ecfi b\u1ecb ph\u00e1 h\u1ee7y, \u0111\u1ed3ng th\u1eddi m\u1edf r\u1ed9ng ph\u1ed5 t\u00e1c d\u1ee5ng l\u00ean nhi\u1ec1u vi khu\u1ea9n \u0111\u00e3 kh\u00e1ng penicilin v\u00e0 cephalosporin.<\/p>\n<p>S\u1ef1 ph\u1ed1i h\u1ee3p c\u1ee7a amoxicilin v\u00e0 acid clavulanic \u0111em l\u1ea1i hi\u1ec7u qu\u1ea3 di\u1ec7t khu\u1ea9n tr\u00ean nhi\u1ec1u ch\u1ee7ng vi khu\u1ea9n g\u00e2y b\u1ec7nh th\u01b0\u1eddng g\u1eb7p nh\u01b0 <em>Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus<\/em> nh\u1ea1y c\u1ea3m, <em>Branhamella catarrhalis<\/em>, k\u1ec3 c\u1ea3 c\u00e1c ch\u1ee7ng sinh men beta-lactamase.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: C\u1ea3 amoxicilin v\u00e0 acid clavulanic c\u00f3 trong vi\u00ean n\u00e9n Cledomox \u0111\u1ec1u \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh qua \u0111\u01b0\u1eddng u\u1ed1ng, \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau 1\u20132 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng c\u1ee7a h\u1ea1ot ch\u1ea5t amoxicilin l\u00e0 ~ 90%, acid clavulanic ~ 75%. Th\u1ee9c \u0103n kh\u00f4ng l\u00e0m gi\u1ea3m h\u1ea5p thu, t\u1ed1t nh\u1ea5t u\u1ed1ng v\u00e0o \u0111\u1ea7u b\u1eefa \u0103n.<\/p>\n<p>Ph\u00e2n b\u1ed1: Thu\u1ed1c ph\u00e2n b\u1ed1 t\u1ed1t v\u00e0o ph\u1ed5i, m\u00e0ng ph\u1ed5i, m\u00e0ng b\u1ee5ng, nhau thai v\u00e0 m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf v\u00e0o s\u1eefa m\u1eb9. Khi m\u00e0ng n\u00e3o vi\u00eam, thu\u1ed1c c\u00f3 th\u1ec3 th\u1ea5m v\u00e0o d\u1ecbch n\u00e3o t\u1ee7y nhi\u1ec1u h\u01a1n. Amoxicilin g\u1eafn protein huy\u1ebft t\u01b0\u01a1ng 17\u201320%, acid clavulanic kho\u1ea3ng 22\u201330%.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Amoxicilin \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a m\u1ed9t ph\u1ea7n th\u00e0nh acid penicilloic kh\u00f4ng c\u00f2n ho\u1ea1t t\u00ednh, trong khi acid clavulanic chuy\u1ec3n h\u00f3a m\u1ea1nh \u1edf gan, s\u1ea3n ph\u1ea9m th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u, ph\u00e2n v\u00e0 kh\u00ed th\u1edf ra d\u01b0\u1edbi d\u1ea1ng CO\u2082.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a amoxicilin kho\u1ea3ng 1\u20132 gi\u1edd, acid clavulanic kho\u1ea3ng 1 gi\u1edd. Amoxicilin \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua th\u1eadn 55\u201370% d\u01b0\u1edbi d\u1ea1ng c\u00f2n ho\u1ea1t t\u00ednh, acid clavulanic kho\u1ea3ng 30\u201340%. Probenecid l\u00e0m ch\u1eadm th\u1ea3i tr\u1eeb c\u1ee7a ho\u1ea1t ch\u1ea5t amoxicilin nh\u01b0ng kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ch\u1ea5t c\u00f2n l\u1ea1i l\u00e0 acid clavulanic.<\/p>\n<h2>Thu\u1ed1c Cledomox 625 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p><span style=\"font-size: 14.4px;\">Nhi\u1ec5m khu\u1ea9n\u00a0 \u0111<\/span>\u01b0\u1eddng h\u00f4 h\u1ea5p tr\u00ean: D\u00f9ng trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh nh\u01b0 vi\u00eam amidan, vi\u00eam xoang, vi\u00eam tai gi\u1eefa, nh\u1ea5t l\u00e0 khi ng\u01b0\u1eddi b\u1ec7nh kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u1edbi c\u00e1c lo\u1ea1i kh\u00e1ng sinh th\u00f4ng th\u01b0\u1eddng.<\/p>\n<p><span style=\"font-size: 14.4px;\">Nhi\u1ec5m khu\u1ea9n\u00a0 \u0111<\/span>\u01b0\u1eddng h\u00f4 h\u1ea5p d\u01b0\u1edbi: Hi\u1ec7u qu\u1ea3 trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p vi\u00eam ph\u1ebf qu\u1ea3n c\u1ea5p v\u00e0 m\u1ea1n t\u00ednh, vi\u00eam ph\u1ed5i \u2013 ph\u1ebf qu\u1ea3n g\u00e2y ra b\u1edfi Haemophilus influenzae ho\u1eb7c Branhamella catarrhalis c\u00f3 kh\u1ea3 n\u0103ng sinh men beta-lactamase.<\/p>\n<p><span style=\"font-size: 14.4px;\">Nhi\u1ec5m khu\u1ea9n\u00a0 \u0111<\/span>\u01b0\u1eddng ti\u1ebft ni\u1ec7u \u2013 sinh d\u1ee5c: \u00c1p d\u1ee5ng cho nhi\u1ec5m khu\u1ea9n do c\u00e1c ch\u1ee7ng E. coli, Klebsiella, Enterobacter sinh beta-lactamase, bao g\u1ed3m vi\u00eam b\u00e0ng quang, vi\u00eam ni\u1ec7u \u0111\u1ea1o, vi\u00eam b\u1ec3 th\u1eadn v\u00e0 m\u1ed9t s\u1ed1 nhi\u1ec5m khu\u1ea9n ph\u1ee5 khoa.<\/p>\n<p><span style=\"font-size: 14.4px;\">Nhi\u1ec5m khu\u1ea9n da v\u00e0 m\u00f4 m\u1ec1m: \u00e1p xe hay m\u1ee5n nh\u1ecdt, th\u1eadm ch\u00ed l\u00e0 v\u1ebft th\u01b0\u01a1ng b\u1ecb nhi\u1ec5m khu\u1ea9n.<\/span><\/p>\n<p>Nhi\u1ec5m khu\u1ea9n x\u01b0\u01a1ng \u2013 kh\u1edbp: vi\u00eam t\u1ee7y x\u01b0\u01a1ng.<\/p>\n<p>Nhi\u1ec5m khu\u1ea9n r\u0103ng mi\u1ec7ng: t\u00ecnh tr\u1ea1ng nhi\u1ec5m tr\u00f9ng nh\u01b0 \u00e1p-xe quanh r\u0103ng.<\/p>\n<p>M\u1ed9t s\u1ed1 nhi\u1ec5m khu\u1ea9n kh\u00e1c: vi\u00eam ph\u00fac m\u1ea1c, nhi\u1ec5m khu\u1ea9n s\u1ea3n \u2013 ph\u1ee5 khoa, nhi\u1ec5m khu\u1ea9n huy\u1ebft, ph\u00f2ng ng\u1eeba nhi\u1ec5m khu\u1ea9n sau ph\u1eabu thu\u1eadt \u1ed5 b\u1ee5ng, ti\u1ebft ni\u1ec7u, ph\u1ee5 khoa, tim, th\u1eadn v\u00e0 thay kh\u1edbp.<\/p>\n<figure id=\"attachment_138817\" aria-describedby=\"caption-attachment-138817\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-138817\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Cledomox-625-.jpg\" alt=\"Cledomox 625\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Cledomox-625-.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Cledomox-625--533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Cledomox-625--1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Cledomox-625--768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Cledomox-625--350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-138817\" class=\"wp-caption-text\">Thu\u1ed1c Cledomox 625 c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb nhi\u1ec1u lo\u1ea1i nhi\u1ec5m khu\u1ea9n nh\u1ea1y c\u1ea3m<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Ng\u01b0\u1eddi l\u1edbn: 1 vi\u00ean (625 mg) u\u1ed1ng m\u1ed7i 12 gi\u1edd.<\/p>\n<p>Tr\u1ebb em \u2265 40 kg: d\u00f9ng li\u1ec1u nh\u01b0 ng\u01b0\u1eddi l\u1edbn.<\/p>\n<p>Tr\u1ebb em &lt; 40 kg: kh\u00f4ng ph\u00f9 h\u1ee3p v\u1edbi d\u1ea1ng 625 mg, c\u1ea7n d\u00f9ng d\u1ea1ng b\u00e0o ch\u1ebf kh\u00e1c.<\/p>\n<p>Suy th\u1eadn: n\u1ebfu ClCr &lt; 30 ml\/ph\u00fat, kh\u00f4ng d\u00f9ng d\u1ea1ng 625 mg; c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u v\u00e0 kho\u1ea3ng c\u00e1ch d\u00f9ng thu\u1ed1c.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>U\u1ed1ng c\u1ea3 <strong>vi\u00ean n\u00e9n Cledomox 625<\/strong> v\u1edbi n\u01b0\u1edbc, c\u00f3 th\u1ec3 b\u1ebb \u0111\u00f4i \u0111\u1ec3 d\u1ec5 nu\u1ed1t nh\u01b0ng ph\u1ea3i u\u1ed1ng c\u1ea3 2 n\u1eeda c\u00f9ng l\u00fac.<\/p>\n<p>U\u1ed1ng v\u00e0o \u0111\u1ea7u b\u1eefa \u0103n \u0111\u1ec3 h\u1ea5p thu t\u1ed1t v\u00e0 gi\u1ea3m t\u00e1c d\u1ee5ng ph\u1ee5 \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/p>\n<p>Kh\u00f4ng d\u00f9ng qu\u00e1 14 ng\u00e0y n\u1ebfu ch\u01b0a \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 l\u1ea1i ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Cledomox 625 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi amoxicilin \u2013 clavulanic c\u00f3 trong Cledomox, \u0111\u1eb7c bi\u1ec7t l\u00e0 nh\u00f3m beta-lactam (penicilin, cephalosporin).<\/p>\n<p>Ng\u01b0\u1eddi t\u1eebng b\u1ecb v\u00e0ng da ho\u1eb7c r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng gan li\u00ean quan \u0111\u1ebfn vi\u1ec7c d\u00f9ng amoxicillin \u2013 clavulanate hay b\u1ea5t k\u1ef3 kh\u00e1ng sinh nh\u00f3m penicillin n\u00e0o kh\u00e1c.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>C\u1ea7n theo d\u00f5i ch\u1ee9c n\u0103ng gan khi s\u1eed d\u1ee5ng, v\u00ec c\u00f3 th\u1ec3 g\u1eb7p v\u00e0ng da \u1ee9 m\u1eadt ho\u1eb7c b\u1ea5t th\u01b0\u1eddng men gan, th\u01b0\u1eddng h\u1ed3i ph\u1ee5c sau khi ng\u1eebng thu\u1ed1c.<\/p>\n<p>\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u d\u00f9ng Cledomox cho ng\u01b0\u1eddi b\u1ec7nh suy th\u1eadn m\u1ee9c \u0111\u1ed9 trung b\u00ecnh \u2013 n\u1eb7ng.<\/p>\n<p>Ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi penicilin khi d\u00f9ng Cledomox c\u00f3 nguy c\u01a1 ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7, th\u1eadm ch\u00ed t\u1eed vong.<\/p>\n<p>Ph\u00e1t ban k\u00e8m s\u1ed1t, n\u1ed5i h\u1ea1ch c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n \u1edf b\u1ec7nh nh\u00e2n d\u00f9ng amoxicilin, c\u1ea7n ng\u1eebng thu\u1ed1c ngay.<\/p>\n<p>D\u00f9ng vi\u00ean n\u00e9n Cledomox k\u00e9o d\u00e0i c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn b\u1ed9i nhi\u1ec5m do vi khu\u1ea9n kh\u00e1ng thu\u1ed1c.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Khi s\u1eed d\u1ee5ng Cledomox 625, c\u00e1c ph\u1ea3n \u1ee9ng kh\u00f4ng mong mu\u1ed1n ch\u1ee7 y\u1ebfu li\u00ean quan \u0111\u1ebfn \u0111\u01b0\u1eddng ti\u00eau h\u00f3a v\u00e0 th\u01b0\u1eddng ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec1u d\u00f9ng. \u0110a s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 m\u1ee9c \u0111\u1ed9 nh\u1eb9 v\u00e0 t\u1ef1 h\u1ed3i ph\u1ee5c, \u00edt khi c\u1ea7n ng\u1eebng thu\u1ed1c.<\/p>\n<p>Th\u01b0\u1eddng g\u1eb7p (tr\u00ean 1\/100 ng\u01b0\u1eddi s\u1eed d\u1ee5ng):<\/p>\n<ul>\n<li>R\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a: ti\u00eau ch\u1ea3y<\/li>\n<li>Ph\u1ea3n \u1ee9ng ngo\u00e0i da: ph\u00e1t ban, ng\u1ee9a<\/li>\n<\/ul>\n<p>\u00cdt g\u1eb7p (t\u1eeb 1\/1.000 \u0111\u1ebfn d\u01b0\u1edbi 1\/100):<\/p>\n<ul>\n<li>M\u00e1u: t\u0103ng b\u1ea1ch c\u1ea7u \u00e1i toan<\/li>\n<li>Ti\u00eau h\u00f3a: bu\u1ed3n n\u00f4n, n\u00f4n<\/li>\n<li>Gan: c\u00f3 th\u1ec3 x\u1ea3y ra t\u00ecnh tr\u1ea1ng vi\u00eam gan, v\u00e0ng da \u1ee9 m\u1eadt, t\u0103ng men gan. C\u00e1c bi\u1ec3u hi\u1ec7n n\u00e0y c\u00f3 th\u1ec3 k\u00e9o d\u00e0i trong v\u00e0i tu\u1ea7n \u0111\u1ebfn v\u00e0i th\u00e1ng.<\/li>\n<li>Da: ban \u0111\u1ecf, n\u1ed5i m\u1ea9n<\/li>\n<\/ul>\n<p>Hi\u1ebfm g\u1eb7p (d\u01b0\u1edbi 1\/1.000):<\/p>\n<ul>\n<li>To\u00e0n th\u00e2n: s\u1ed1c ph\u1ea3n v\u1ec7, ph\u00f9 Quincke<\/li>\n<li>Huy\u1ebft h\u1ecdc: gi\u1ea3m ti\u1ec3u c\u1ea7u, thi\u1ebfu m\u00e1u tan m\u00e1u, gi\u1ea3m b\u1ea1ch c\u1ea7u<\/li>\n<li>Ti\u00eau h\u00f3a: vi\u00eam \u0111\u1ea1i tr\u00e0ng gi\u1ea3 m\u1ea1c<\/li>\n<li>Da: h\u1ed9i ch\u1ee9ng Stevens-Johnson, vi\u00eam da tr\u00f3c v\u1ea3y, ban \u0111\u1ecf \u0111a d\u1ea1ng<\/li>\n<li>Th\u1eadn: vi\u00eam th\u1eadn k\u1ebd<\/li>\n<\/ul>\n<p><em><strong>X\u1eed tr\u00ed<\/strong><\/em><\/p>\n<p>Trong tr\u01b0\u1eddng h\u1ee3p ph\u1ea3n v\u1ec7 n\u1eb7ng c\u1ea7n x\u1eed l\u00fd kh\u1ea9n c\u1ea5p b\u1eb1ng epinephrin, corticoid ti\u00eam, li\u1ec7u ph\u00e1p oxy v\u00e0 th\u00f4ng kh\u00ed h\u1ed7 tr\u1ee3.<\/p>\n<p>T\u0103ng nh\u1eb9 transaminase th\u01b0\u1eddng kh\u00f4ng r\u00f5 \u00fd ngh\u0129a l\u00e2m s\u00e0ng nh\u01b0ng c\u1ea7n theo d\u00f5i, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi l\u1edbn tu\u1ed5i.<\/p>\n<p>Khi c\u00f3 bi\u1ec3u hi\u1ec7n ph\u00e1t ban nghi\u00eam tr\u1ecdng, c\u1ea7n ng\u1eebng thu\u1ed1c ngay.<\/p>\n<p>N\u1ebfu x\u1ea3y ra vi\u00eam \u0111\u1ea1i tr\u00e0ng gi\u1ea3 m\u1ea1c:<\/p>\n<ul>\n<li>Tr\u01b0\u1eddng h\u1ee3p nh\u1eb9: ng\u01b0ng thu\u1ed1c.<\/li>\n<li>Tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng: \u0111i\u1ec1u tr\u1ecb b\u00f9 n\u01b0\u1edbc, \u0111i\u1ec7n gi\u1ea3i v\u00e0 d\u00f9ng kh\u00e1ng sinh \u0111\u1eb7c hi\u1ec7u ch\u1ed1ng l\u1ea1i Clostridium difficile.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Ho\u1ea1t ch\u1ea5t trong thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m k\u00e9o d\u00e0i th\u1eddi gian \u0111\u00f4ng m\u00e1u, do \u0111\u00f3 c\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng Cledomox 625 c\u00f9ng thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng nh\u01b0 warfarin.<\/p>\n<p>V\u00ec c\u00f3 b\u1ea3n ch\u1ea5t l\u00e0 kh\u00e1ng sinh ph\u1ed5 r\u1ed9ng n\u00ean Cledomox 625 d\u00f9ng c\u00f9ng thu\u1ed1c tr\u00e1nh thai d\u1ea1ng u\u1ed1ng th\u00ec c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y.<\/p>\n<p>Khi d\u00f9ng chung v\u1edbi nifedipin, kh\u1ea3 n\u0103ng h\u1ea5p thu amoxicillin t\u0103ng l\u00ean.<\/p>\n<p>D\u00f9ng amoxicillin k\u1ebft h\u1ee3p v\u1edbi thu\u1ed1c ch\u1ee9a allopurinol c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 n\u1ed5i m\u1ea9n.<\/p>\n<p>C\u00f3 th\u1ec3 x\u1ea3y ra \u0111\u1ed1i kh\u00e1ng gi\u1eefa amoxicillin (thu\u1ed1c di\u1ec7t khu\u1ea9n) v\u1edbi c\u00e1c thu\u1ed1c k\u00ecm khu\u1ea9n c\u00f3 th\u1ec3 k\u1ec3 \u0111\u1ebfn nh\u01b0 tetracyclin, chloramphenicol, acid fusidic.<\/p>\n<p>Amoxicillin l\u00e0m gi\u1ea3m th\u1ea3i tr\u1eeb methotrexat, t\u1eeb \u0111\u00f3 t\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a ho\u1ea1t ch\u1ea5t n\u00e0y khi d\u00f9ng c\u00f9ng tr\u00ean m\u00e1u v\u00e0 th\u1eadn.<\/p>\n<p>Probenecid l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 amoxicillin trong m\u00e1u khi d\u00f9ng c\u00f9ng l\u00fac, nh\u01b0ng kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn \u0111\u1eb7c t\u00ednh d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a acid clavulanic.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef mang thai Th\u1eed nghi\u1ec7m tr\u00ean \u0111\u1ed9ng v\u1eadt cho th\u1ea5y thu\u1ed1c kh\u00f4ng g\u00e2y d\u1ecb t\u1eadt b\u1ea9m sinh. Tuy nhi\u00ean, v\u00ec d\u1eef li\u1ec7u l\u00e2m s\u00e0ng tr\u00ean ng\u01b0\u1eddi c\u00f2n h\u1ea1n ch\u1ebf, \u0111\u1eb7c bi\u1ec7t trong 3 th\u00e1ng \u0111\u1ea7u thai k\u1ef3, ch\u1ec9 n\u00ean s\u1eed d\u1ee5ng khi th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft v\u00e0 c\u00f3 ch\u1ec9 \u0111\u1ecbnh t\u1eeb b\u00e1c s\u0129.<\/p>\n<p>Ph\u1ee5 n\u1eef cho con b\u00fa: Thu\u1ed1c c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng trong giai \u0111o\u1ea1n cho con b\u00fa. Tuy c\u00f3 m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf thu\u1ed1c b\u00e0i ti\u1ebft qua s\u1eefa, nh\u01b0ng kh\u00f4ng g\u00e2y h\u1ea1i r\u00f5 r\u00e0ng cho tr\u1ebb b\u00fa m\u1eb9, tr\u1eeb tr\u01b0\u1eddng h\u1ee3p tr\u1ebb nh\u1ea1y c\u1ea3m ho\u1eb7c c\u00f3 nguy c\u01a1 d\u1ecb \u1ee9ng.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng \u0111i\u1ec1u khi\u1ec3n ph\u01b0\u01a1ng ti\u1ec7n giao th\u00f4ng hay v\u1eadn h\u00e0nh m\u00e1y m\u00f3c. Ng\u01b0\u1eddi d\u00f9ng c\u00f3 th\u1ec3 ti\u1ebfp t\u1ee5c c\u00e1c ho\u1ea1t \u0111\u1ed9ng n\u00e0y trong khi \u0111i\u1ec1u tr\u1ecb n\u1ebfu kh\u00f4ng g\u1eb7p t\u00e1c d\u1ee5ng ph\u1ee5 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn nh\u1eadn th\u1ee9c ho\u1eb7c th\u1ec3 ch\u1ea5t.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tri\u1ec7u ch\u1ee9ng: Khi d\u00f9ng qu\u00e1 li\u1ec1u Cledomox 625 so v\u1edbi khuy\u1ebfn c\u00e1o c\u1ee7a b\u00e1c s\u0129 hay nh\u00e0 s\u1ea3n xu\u1ea5t, thu\u1ed1c \u00edt g\u00e2y bi\u1ebfn ch\u1ee9ng nghi\u00eam tr\u1ecdng do dung n\u1ea1p t\u1ed1t. Tuy nhi\u00ean, trong tr\u01b0\u1eddng h\u1ee3p ch\u1ee9c n\u0103ng th\u1eadn suy gi\u1ea3m ho\u1eb7c h\u00e0ng r\u00e0o m\u00e1u n\u00e3o t\u1ed5n th\u01b0\u01a1ng, c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n bi\u1ec3u hi\u1ec7n nhi\u1ec5m \u0111\u1ed9c. \u1ede li\u1ec1u r\u1ea5t cao, nguy c\u01a1 t\u0103ng kali huy\u1ebft c\u1ea7n \u0111\u01b0\u1ee3c l\u01b0u \u00fd v\u00ec acid clavulanic l\u00e0 mu\u1ed1i kali.<\/p>\n<p>X\u1eed l\u00fd: C\u00f3 th\u1ec3 lo\u1ea1i b\u1ecf Cledomox kh\u1ecfi tu\u1ea7n ho\u00e0n b\u1eb1ng th\u1ea9m ph\u00e2n m\u00e1u trong tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u n\u1eb7ng. C\u00e1c ph\u1ea3n \u1ee9ng c\u1ea5p t\u00ednh th\u01b0\u1eddng ph\u1ee5 thu\u1ed9c v\u00e0o c\u01a1 \u0111\u1ecba m\u1ed7i ng\u01b0\u1eddi.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Cledomox 625 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Cledomox 625 trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Cledomox 625 khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Cledomox 625 nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/augmentin-625mg\/\">Augmentin 625mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Amoxicillin 500mg v\u00e0 Acid clavulanic 125mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi SmithKline Beecham Pharmaceuticals, \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n nh\u1ea1y c\u1ea3m<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/midantin-500-125\/\">Midantin 500\/125<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Amoxicillin 500mg v\u00e0 Acid clavulanic 125mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Minh D\u00e2n, \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n nh\u1ea1y c\u1ea3m<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Cledomox 625 \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 t\u1ea1i \u0111\u00e2y. Truy c\u1eadp ng\u00e0y 15 th\u00e1ng 9 n\u0103m 2025<\/li>\n<li>Salvo F, De Sarro A, Caputi AP, Polimeni G. Amoxicillin and amoxicillin plus clavulanate: a safety review. Expert Opin Drug Saf. Truy c\u1eadp ng\u00e0y 15 th\u00e1ng 9 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19236222\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/19236<\/a>222\/<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Cledomox 625 l\u00e0 thu\u1ed1c kh\u00e1ng sinh ph\u1ed1i h\u1ee3p gi\u1eefa amoxicilin v\u00e0 acid clavulanic, thu\u1ed9c nh\u00f3m beta-lactam, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb nhi\u1ec1u lo\u1ea1i nhi\u1ec5m khu\u1ea9n do vi khu\u1ea9n nh\u1ea1y c\u1ea3m.<\/p>\n","protected":false},"author":1,"featured_media":138818,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-138815","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/138815","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=138815"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/138818"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=138815"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=138815"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=138815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}