{"id":138689,"date":"2025-09-13T15:35:09","date_gmt":"2025-09-13T08:35:09","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=138689"},"modified":"2025-09-13T16:58:35","modified_gmt":"2025-09-13T09:58:35","slug":"dogrel-savi-75mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/dogrel-savi-75mg\/","title":{"rendered":"Dogrel SaVi 75mg"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Dogrel SaVi 75mg c\u00f3 c\u01a1 s\u1edf s\u1ea3n xu\u1ea5t l\u00e0 C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Sa Vi (SaViPharm), \u0111\u01b0\u1ee3c l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam v\u1edbi s\u1ed1 \u0111\u0103ng k\u00fd l\u00e0 VD-17939-12.<\/strong><\/p>\n<h2 style=\"text-align: justify;\">Dogrel SaVi 75mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3 style=\"text-align: justify;\">Th\u00e0nh ph\u1ea7n<\/h3>\n<p style=\"text-align: justify;\">M\u1ed7i vi\u00ean<strong> Dogrel SaVi 75mg <\/strong>ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul style=\"text-align: justify;\">\n<li>Clopidogrel 75mg (d\u1ea1ng bisulfat)<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/li>\n<\/ul>\n<p style=\"text-align: justify;\">D\u1ea1ng b\u00e0o ch\u1ebf : Vi\u00ean n\u00e9n bao phim<\/p>\n<h3 style=\"text-align: justify;\">Tr\u00ecnh b\u00e0y<\/h3>\n<p style=\"text-align: justify;\">S\u0110K: VD-17939-12<\/p>\n<p style=\"text-align: justify;\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p style=\"text-align: justify;\">Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<h2 style=\"text-align: justify;\">T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Dogrel SaVi 75mg<\/h2>\n<h3 style=\"text-align: justify;\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Clopidogrel l\u00e0 ti\u1ec1n ch\u1ea5t \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a \u1edf gan th\u00e0nh ch\u1ea5t c\u00f3 ho\u1ea1t t\u00ednh \u1ee9c ch\u1ebf k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u. C\u01a1 ch\u1ebf l\u00e0 \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 ADP v\u1ecb tr\u00ed P2Y12 tr\u00ean b\u1ec1 m\u1eb7t ti\u1ec3u c\u1ea7u l\u00e0m gi\u1ea3m k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u.<\/p>\n<h3 style=\"text-align: justify;\">\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu : Clopidogrel h\u1ea5p thu nhanh qua \u0111\u01b0\u1eddng u\u1ed1ng nh\u01b0ng sinh kh\u1ea3 d\u1ee5ng h\u1ec7 th\u1ed1ng th\u1ea5p do chuy\u1ec3n h\u00f3a l\u1ea7n \u0111\u1ea7u \u1edf gan.<\/p>\n<p>Ph\u00e2n b\u1ed1 : Clopidogrel v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh li\u00ean k\u1ebft ch\u1eb7t ch\u1ebd v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng.<\/p>\n<p>Chuy\u1ec3n h\u00f3a : Clopidogrel chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu \u1edf gan qua isoenzym CYP2C19 \u0111\u1ec3 t\u1ea1o d\u1ea1ng thiol ho\u1ea1t t\u00ednh. Bi\u1ebfn d\u1ecb di truy\u1ec1n c\u1ee7a CYP2C19 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 thu\u1ed1c.<\/p>\n<p>Th\u1ea3i tr\u1eeb : C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 ph\u00e2n. Kho\u1ea3ng 50% li\u1ec1u \u0111\u01b0\u1ee3c th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 46% qua ph\u00e2n. Th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a d\u1eabn xu\u1ea5t acid carboxylic kho\u1ea3ng 8 gi\u1edd.<\/p>\n<h2 style=\"text-align: justify;\">Dogrel SaVi 75mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p style=\"text-align: justify;\"><strong>Dogrel SaVi 75mg Calci carbonat<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong :<\/p>\n<ul>\n<li>D\u1ef1 ph\u00f2ng nguy c\u01a1 bi\u1ebfn c\u1ed1 tim m\u1ea1ch sau nh\u1ed3i m\u00e1u c\u01a1 tim \u0111\u1ed9t qu\u1ef5 v\u00e0 b\u1ec7nh m\u1ea1ch ngo\u1ea1i bi\u00ean.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb h\u1ed9i ch\u1ee9ng m\u1ea1ch v\u00e0nh c\u1ea5p bao g\u1ed3m \u0111au th\u1eaft ng\u1ef1c kh\u00f4ng \u1ed5n \u0111\u1ecbnh v\u00e0 nh\u1ed3i m\u00e1u c\u01a1 tim c\u00f3 ho\u1eb7c kh\u00f4ng c\u00f3 ST ch\u00eanh l\u00ean.<\/li>\n<li>Thay th\u1ebf aspirin \u1edf b\u1ec7nh nh\u00e2n \u0111au th\u1eaft ng\u1ef1c \u1ed5n \u0111\u1ecbnh kh\u00f4ng dung n\u1ea1p aspirin ho\u1eb7c ph\u1ed1i h\u1ee3p v\u1edbi aspirin \u1edf b\u1ec7nh nh\u00e2n m\u1ea1ch v\u00e0nh c\u00f3 nguy c\u01a1 cao v\u00e0 sau \u0111\u1eb7t stent \u0111\u1ec3 d\u1ef1 ph\u00f2ng t\u00e1i h\u1eb9p.<\/li>\n<\/ul>\n<figure id=\"attachment_138690\" aria-describedby=\"caption-attachment-138690\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-138690\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/dogrel-savi-75mg-giam-nguy-co-tai-bien-tim-mach.jpg\" alt=\"Dogrel SaVi 75mg gi\u1ea3m nguy c\u01a1 tai bi\u1ebfn tim m\u1ea1ch\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/dogrel-savi-75mg-giam-nguy-co-tai-bien-tim-mach.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/dogrel-savi-75mg-giam-nguy-co-tai-bien-tim-mach-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/dogrel-savi-75mg-giam-nguy-co-tai-bien-tim-mach-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/dogrel-savi-75mg-giam-nguy-co-tai-bien-tim-mach-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/dogrel-savi-75mg-giam-nguy-co-tai-bien-tim-mach-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-138690\" class=\"wp-caption-text\">Dogrel SaVi 75mg gi\u1ea3m nguy c\u01a1 tai bi\u1ebfn tim m\u1ea1ch<\/figcaption><\/figure>\n<h2 style=\"text-align: justify;\">Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Dogrel SaVi 75mg<\/h2>\n<h4>Sau nh\u1ed3i m\u00e1u c\u01a1 tim \u0111\u1ed9t qu\u1ef5 v\u00e0 b\u1ec7nh m\u1ea1ch ngo\u1ea1i bi\u00ean<\/h4>\n<p>Li\u1ec1u th\u00f4ng th\u01b0\u1eddng : 75mg\/l\u1ea7n, 1 l\u1ea7n\/ng\u00e0y.<\/p>\n<h4>H\u1ed9i ch\u1ee9ng m\u1ea1ch v\u00e0nh c\u1ea5p<\/h4>\n<p>\u0110au th\u1eaft ng\u1ef1c kh\u00f4ng \u1ed5n \u0111\u1ecbnh v\u00e0 nh\u1ed3i m\u00e1u c\u01a1 tim kh\u00f4ng c\u00f3 ST ch\u00eanh l\u00ean : N\u1ebfu d\u1ef1 ki\u1ebfn can thi\u1ec7p m\u1ea1ch v\u00e0nh qua da: li\u1ec1u n\u1ea1p 300mg u\u1ed1ng 1 l\u1ea7n \u00edt nh\u1ea5t 2 gi\u1edd tr\u01b0\u1edbc can thi\u1ec7p, sau \u0111\u00f3 duy tr\u00ec 75mg\/l\u1ea7n, 1 l\u1ea7n\/ng\u00e0y k\u1ebft h\u1ee3p v\u1edbi aspirin 75\u2013325mg\/ng\u00e0y.<\/p>\n<p>N\u1ebfu kh\u00f4ng th\u1ec3 d\u00f9ng aspirin: li\u1ec1u n\u1ea1p 300\u2013600mg u\u1ed1ng 1 l\u1ea7n \u00edt nh\u1ea5t 24 gi\u1edd tr\u01b0\u1edbc can thi\u1ec7p, sau \u0111\u00f3 duy tr\u00ec 75mg\/l\u1ea7n, 1 l\u1ea7n\/ng\u00e0y trong \u00edt nh\u1ea5t 12 th\u00e1ng.<\/p>\n<h4>Nh\u1ed3i m\u00e1u c\u01a1 tim c\u00f3 ST ch\u00eanh l\u00ean<\/h4>\n<p>Li\u1ec1u duy tr\u00ec : 75mg\/l\u1ea7n, 1 l\u1ea7n\/ng\u00e0y ph\u1ed1i h\u1ee3p v\u1edbi aspirin 75\u2013162mg\/ng\u00e0y.<\/p>\n<p>C\u00f3 th\u1ec3 d\u00f9ng li\u1ec1u n\u1ea1p 300\u2013600mg u\u1ed1ng 1 l\u1ea7n n\u1ebfu c\u1ea7n can thi\u1ec7p m\u1ea1ch v\u00e0nh. Sau can thi\u1ec7p ti\u1ebfp t\u1ee5c duy tr\u00ec 75mg\/l\u1ea7n, 1 l\u1ea7n\/ng\u00e0y k\u00e9o d\u00e0i \u00edt nh\u1ea5t 12 th\u00e1ng.<\/p>\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb c\u1ea5p t\u00ednh ban \u0111\u1ea7u th\u01b0\u1eddng ng\u1eafn h\u1ea1n theo ch\u1ec9 \u0111\u1ecbnh l\u00e2m s\u00e0ng.<\/p>\n<h4>\u0110\u1eb7t stent \u0111\u1ed9ng m\u1ea1ch v\u00e0nh (b\u1ec7nh nh\u00e2n kh\u00f4ng c\u00f3 nguy c\u01a1 ch\u1ea3y m\u00e1u cao)<\/h4>\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb l\u00fd t\u01b0\u1edfng 12 th\u00e1ng sau \u0111\u1eb7t stent gi\u1ea3i ph\u00f3ng thu\u1ed1c ch\u1eadm.<\/p>\n<p>Li\u1ec1u duy tr\u00ec : 75mg\/l\u1ea7n, 1 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>Th\u1eddi gian t\u1ed1i thi\u1ec3u th\u01b0\u1eddng l\u00e0 1 th\u00e1ng cho stent kim lo\u1ea1i tr\u1ea7n, 3 th\u00e1ng cho stent gi\u1ea3i ph\u00f3ng sirolimus v\u00e0 6 th\u00e1ng cho stent gi\u1ea3i ph\u00f3ng paclitaxel.<\/p>\n<p>Ng\u1eebng thu\u1ed1c s\u1edbm c\u00f3 th\u1ec3 g\u00e2y huy\u1ebft kh\u1ed1i trong stent d\u1eabn t\u1edbi nh\u1ed3i m\u00e1u c\u01a1 tim ho\u1eb7c t\u1eed vong.<\/p>\n<h4>\u0110\u1ed1i t\u01b0\u1ee3ng \u0111\u1eb7c bi\u1ec7t<\/h4>\n<p>Ng\u01b0\u1eddi cao tu\u1ed5i kh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u. Hi\u1ec7u ch\u1ec9nh li\u1ec1u cho suy th\u1eadn th\u01b0\u1eddng kh\u00f4ng c\u1ea7n thi\u1ebft theo d\u1eef li\u1ec7u hi\u1ec7n c\u00f3.<\/p>\n<p>Tr\u1ebb em : D\u1eef li\u1ec7u h\u1ea1n ch\u1ebf. Tr\u1ebb &lt; 24 th\u00e1ng: 0,2 mg\/kg\/l\u1ea7n\/ng\u00e0y. Tr\u1ebb tr\u00ean 2 tu\u1ed5i ch\u01b0a c\u00f3 khuy\u1ebfn c\u00e1o li\u1ec1u t\u1ed1i \u01b0u, kh\u00f4ng d\u00f9ng v\u01b0\u1ee3t qu\u00e1 li\u1ec1u ng\u01b0\u1eddi l\u1edbn, c\u00f3 th\u1ec3 kh\u1edfi \u0111\u1ea7u v\u1edbi li\u1ec1u 1mg\/kg sau \u0111\u00f3 hi\u1ec7u ch\u1ec9nh theo \u0111\u00e1p \u1ee9ng.<\/p>\n<p>Suy th\u1eadn : Kh\u00f4ng c\u00f3 khuy\u1ebfn c\u00e1o hi\u1ec7u ch\u1ec9nh li\u1ec1u c\u1ee5 th\u1ec3 nh\u01b0ng c\u1ea7n theo d\u00f5i ch\u1ea3y m\u00e1u v\u00e0 hi\u1ec7u qu\u1ea3 l\u00e2m s\u00e0ng.<\/p>\n<h2 style=\"text-align: justify;\">C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Dogrel SaVi 75mg<\/h2>\n<p>Thu\u1ed1c Dogrel SaVi 75mg \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng. C\u00f3 th\u1ec3 d\u00f9ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng b\u1eefa \u0103n.<\/p>\n<h2 style=\"text-align: justify;\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Dogrel SaVi 75mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Kh\u00f4ng d\u00f9ng Dogrel SaVi 75mg cho ng\u01b0\u1eddi c\u00f3 m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>Suy gan n\u1eb7ng.<\/p>\n<p>\u0110ang b\u1ecb lo\u00e9t ti\u00eau h\u00f3a ho\u1eb7c ch\u1ea3y m\u00e1u n\u1ed9i s\u1ecd.<\/p>\n<h2 style=\"text-align: justify;\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Dogrel SaVi 75mg<\/h2>\n<h3 style=\"text-align: justify;\">Th\u1eadn tr\u1ecdng<\/h3>\n<p>Kh\u00f4ng n\u00ean b\u1eaft \u0111\u1ea7u clopidogrel ngay trong v\u00e0i ng\u00e0y \u0111\u1ea7u sau nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p n\u1ebfu kh\u00f4ng c\u00f3 ch\u1ec9 \u0111\u1ecbnh r\u00f5 r\u00e0ng do nguy c\u01a1 ch\u1ea3y m\u00e1u.<\/p>\n<p>Th\u1eadn tr\u1ecdng \u1edf b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 ch\u1ea3y m\u00e1u cao do ch\u1ea5n th\u01b0\u01a1ng ph\u1eabu thu\u1eadt ho\u1eb7c t\u1ed5n th\u01b0\u01a1ng. N\u1ebfu c\u1ea7n ng\u01b0ng \u0111\u1ec3 ph\u1eabu thu\u1eadt, n\u00ean d\u1eebng thu\u1ed1c tr\u01b0\u1edbc 5\u20137 ng\u00e0y t\u00f9y theo h\u01b0\u1edbng d\u1eabn ph\u1eabu thu\u1eadt.<\/p>\n<p>Th\u1eadn tr\u1ecdng \u1edf b\u1ec7nh nh\u00e2n d\u1ec5 ch\u1ea3y m\u00e1u, \u0111\u1eb7c bi\u1ec7t \u1edf d\u1ea1 d\u00e0y &#8211; ru\u1ed9t v\u00e0 n\u1ed9i nh\u00e3n v\u00ec clopidogrel k\u00e9o d\u00e0i th\u1eddi gian ch\u1ea3y m\u00e1u.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng cho b\u1ec7nh nh\u00e2n suy th\u1eadn do d\u1eef li\u1ec7u c\u00f2n h\u1ea1n ch\u1ebf, c\u1ea7n theo d\u00f5i ch\u1ea3y m\u00e1u v\u00e0 hi\u1ec7u qu\u1ea3 l\u00e2m s\u00e0ng.<\/p>\n<p>Th\u1eadn tr\u1ecdng \u1edf b\u1ec7nh nh\u00e2n suy gan nh\u1eb9 \u0111\u1ebfn v\u1eeba v\u00ec r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng gan c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u, kh\u00f4ng d\u00f9ng khi suy gan n\u1eb7ng.<\/p>\n<h3 style=\"text-align: justify;\">T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Hay g\u1eb7p : r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a, \u0111au b\u1ee5ng, n\u00f4n, ch\u00e1n \u0103n, vi\u00eam d\u1ea1 d\u00e0y, t\u00e1o b\u00f3n, \u0111au ng\u1ef1c, ph\u00f9 m\u1ea1ch, t\u0103ng huy\u1ebft \u00e1p, \u0111au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, m\u1ec7t m\u1ecfi, \u0111au m\u1ecfi ng\u01b0\u1eddi, ng\u1ee9a, ban \u0111\u1ecf, t\u0103ng cholesterol m\u00e1u, nhi\u1ec5m khu\u1ea9n ti\u1ebft ni\u1ec7u, ch\u1ea3y m\u00e1u, ch\u1ee9c n\u0103ng gan b\u1ea5t th\u01b0\u1eddng, \u0111au kh\u1edbp, \u0111au l\u01b0ng, kh\u00f3 th\u1edf, vi\u00eam m\u0169i, vi\u00eam ph\u1ebf qu\u1ea3n, nhi\u1ec5m tr\u00f9ng h\u00f4 h\u1ea5p tr\u00ean, h\u1ed9i ch\u1ee9ng gi\u1ea3 c\u00fam.<\/p>\n<p>Th\u01b0\u1eddng g\u1eb7p : rung nh\u0129 suy tim nh\u1ecbp nhanh ng\u1ea5t, s\u1ed1t, m\u1ea5t ng\u1ee7, ch\u00f3ng m\u1eb7t, lo \u00e2u, ch\u00e0m, t\u0103ng uric m\u00e1u, t\u00e1o b\u00f3n, ch\u1ea3y m\u00e1u ti\u00eau h\u00f3a, n\u00f4n, vi\u00eam b\u00e0ng quang, thi\u1ebfu m\u00e1u, chu\u1ed9t r\u00fat, \u0111au d\u00e2y th\u1ea7n kinh, y\u1ebfu c\u01a1, \u0111\u1ee5c th\u1ee7y tinh th\u1ec3, vi\u00eam k\u1ebft m\u1ea1c.<\/p>\n<p>\u00cdt g\u1eb7p : suy gan c\u1ea5p, m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t, d\u1ecb \u1ee9ng ph\u1ea3n v\u1ec7, ph\u00e1t ban, ph\u00f9 m\u1ea1ch, thi\u1ebfu m\u00e1u, t\u0103ng bilirubin, co th\u1eaft ph\u1ebf qu\u1ea3n, h\u1ed3ng ban \u0111a d\u1ea1ng, ch\u1ea3y m\u00e1u m\u00e0ng ph\u1ed5i, vi\u00eam gan, vi\u00eam ph\u1ed5i k\u1ebd, ch\u1ea3y m\u00e1u n\u1ed9i s\u1ecd, ho\u1ea1i t\u1eed thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9, ch\u1ea3y m\u00e1u n\u1ed9i nh\u00e3n, vi\u00eam t\u1ee5y, h\u1ed9i ch\u1ee9ng Stevens-Johnson, gi\u1ea3m ti\u1ec3u c\u1ea7u, xu\u1ea5t huy\u1ebft gi\u1ea3m ti\u1ec3u c\u1ea7u, ho\u1ea1i t\u1eed da nhi\u1ec5m \u0111\u1ed9c, vi\u00eam m\u1ea1ch, gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh tr\u1ea7m tr\u1ecdng.<\/p>\n<h3 style=\"text-align: justify;\">T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng acid acetylsalicylic (aspirin) do t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c l\u1ef1c h\u1ecdc l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng warfarin do t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c l\u1ef1c h\u1ecdc l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u v\u00e0 c\u1ea7n theo d\u00f5i ch\u1ea3y m\u00e1u ch\u1eb7t ch\u1ebd.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng heparin do t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c l\u1ef1c h\u1ecdc l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u khi ph\u1ed1i h\u1ee3p trong \u0111i\u1ec1u tr\u1ecb c\u1ea5p t\u00ednh ho\u1eb7c tr\u01b0\u1edbc ph\u1eabu thu\u1eadt.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf glycoprotein IIb\/IIIa nh\u01b0 abciximab do ph\u1ed1i h\u1ee3p c\u00f3 th\u1ec3 gia t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u sau ph\u1eabu thu\u1eadt ho\u1eb7c ch\u1ea5n th\u01b0\u01a1ng.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng Dogrel SaVi 75mg c\u00f9ng c\u00e1c thu\u1ed1c kh\u00e1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u kh\u00e1c nh\u01b0 ticlopidine eptifibatide tirofiban do t\u00e1c d\u1ee5ng c\u1ed9ng g\u1ed9p l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf CYP2C19 do l\u00e0m gi\u1ea3m chuy\u1ec3n h\u00f3a th\u00e0nh d\u1ea1ng ho\u1ea1t t\u00ednh c\u1ee7a clopidogrel v\u00e0 gi\u1ea3m hi\u1ec7u qu\u1ea3 kh\u00e1ng ti\u1ec3u c\u1ea7u.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng Dogrel SaVi 75mg c\u00f9ng c\u00e1c thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a b\u1edfi CYP2C9 do clopidogrel c\u00f3 th\u1ec3 can thi\u1ec7p v\u00e0o chuy\u1ec3n h\u00f3a v\u00e0 l\u00e0m thay \u0111\u1ed5i n\u1ed3ng \u0111\u1ed9 thu\u1ed1c kh\u00e1c, c\u1ea7n c\u00e2n nh\u1eafc v\u00e0 theo d\u00f5i l\u00e2m s\u00e0ng.<\/p>\n<p>Th\u1eadn tr\u1ecdng chung khi k\u1ebft h\u1ee3p nhi\u1ec1u thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng ho\u1eb7c kh\u00e1ng ti\u1ec3u c\u1ea7u do nguy c\u01a1 ch\u1ea3y m\u00e1u t\u0103ng theo s\u1ed1 l\u01b0\u1ee3ng thu\u1ed1c.<\/p>\n<h3 style=\"text-align: justify;\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa.<\/p>\n<h3 style=\"text-align: justify;\">Kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p style=\"text-align: justify;\">Dogrel SaVi 75mg kh\u00f4ng \u1ea3nh h\u01b0\u1edfng l\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3 style=\"text-align: justify;\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p style=\"text-align: justify;\">X\u1eed tr\u00ed : B\u00e1o ngay v\u1edbi b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb v\u00e0 \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf g\u1ea7n nh\u1ea5t \u0111\u1ec3 ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng k\u1ecbp th\u1eddi.<\/p>\n<h3 style=\"text-align: justify;\">B\u1ea3o qu\u1ea3n<\/h3>\n<p style=\"text-align: justify;\">\u0110\u1ec3 thu\u1ed1c tr\u00e1nh xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<p style=\"text-align: justify;\">B\u1ea3o qu\u1ea3n thu\u1ed1c \u1edf nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30 \u0111\u1ed9 C, tr\u00e1nh \u00e1nh n\u1eafng tr\u1ef1c ti\u1ebfp t\u1eeb m\u1eb7t tr\u1eddi.<\/p>\n<h2 style=\"text-align: justify;\">S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p style=\"text-align: justify;\">Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<\/p>\n<ul>\n<li><a href=\"https:\/\/vnras.com\/drug\/clopidogrel-75-mv\/\">Clopidogrel 75-MV<\/a> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh d\u1ef1 ph\u00f2ng th\u1ee9 ph\u00e1t c\u00e1c bi\u1ebfn c\u1ed1 huy\u1ebft kh\u1ed1i do x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch v\u00e0 t\u1eafc m\u1ea1ch do huy\u1ebft kh\u1ed1i trong rung nh\u0129 \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh.<\/li>\n<li><a href=\"https:\/\/vnras.com\/drug\/noklot-75mg\/\">Noklot 75mg<\/a> ph\u00f2ng ng\u1eeba c\u00e1c bi\u1ebfn c\u1ed1 do x\u01a1 v\u1eefa m\u1ea1ch \u1edf b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed nh\u1ed3i m\u00e1u c\u01a1 tim, \u0111\u1ed9t qu\u1ef5 g\u1ea7n \u0111\u00e2y ho\u1eb7c b\u1ec7nh l\u00fd \u0111\u1ed9ng m\u1ea1ch ngo\u1ea1i bi\u00ean \u0111\u00e3 \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh.<\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Jiang, X. L., Samant, S., Lesko, L. J., &amp; Schmidt, S. (2015). Clinical pharmacokinetics and pharmacodynamics of clopidogrel. Truy c\u1eadp ng\u00e0y 13\/09\/2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25559342\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/25559342\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Dogrel SaVi 75mg d\u1ef1 ph\u00f2ng nguy c\u01a1 bi\u1ebfn c\u1ed1 tim m\u1ea1ch sau nh\u1ed3i m\u00e1u c\u01a1 tim, \u0111\u1ed9t qu\u1ef5 v\u00e0 \u0111i\u1ec1u tr\u1ecb h\u1ed9i ch\u1ee9ng m\u1ea1ch v\u00e0nh c\u1ea5p nh\u01b0 \u0111au th\u1eaft ng\u1ef1c kh\u00f4ng \u1ed5n \u0111\u1ecbnh.<\/p>\n","protected":false},"author":1,"featured_media":138691,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-138689","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/138689","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=138689"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/138691"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=138689"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=138689"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=138689"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}