{"id":138682,"date":"2025-09-13T15:13:10","date_gmt":"2025-09-13T08:13:10","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=138682"},"modified":"2026-01-04T13:17:59","modified_gmt":"2026-01-04T06:17:59","slug":"lisiplus-hct-10-12-5","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/lisiplus-hct-10-12-5\/","title":{"rendered":"Lisiplus HCT 10\/12.5"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Lisiplus HCT 10\/12.5 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean Doanh Stellapharm &#8211; Chi nh\u00e1nh 1, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-17766-12.<\/strong><\/p>\n<h2>Lisiplus HCT 10\/12.5 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Lisiplus HCT 10\/12.5<\/strong> l\u00e0 m\u1ed9t thu\u1ed1c k\u00ea \u0111\u01a1n, m\u1ed7i vi\u00ean n\u00e9n ch\u1ee9a:<\/p>\n<ul>\n<li><strong>Lisinopril<\/strong> (d\u01b0\u1edbi d\u1ea1ng Lisinopril dihydrat): 10mg<\/li>\n<li>Hydrochlorothiazide: 12.5mg<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-17766-12<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean; H\u1ed9p 6 v\u1ec9 x 10 vi\u00ean; H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean.<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_138683\" aria-describedby=\"caption-attachment-138683\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-138683\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Lisiplus-HCT-1012.5.jpg\" alt=\"Lisiplus HCT 10\/12.5 \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p nguy\u00ean ph\u00e1t\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Lisiplus-HCT-1012.5.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Lisiplus-HCT-1012.5-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Lisiplus-HCT-1012.5-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Lisiplus-HCT-1012.5-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Lisiplus-HCT-1012.5-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-138683\" class=\"wp-caption-text\">Lisiplus HCT 10\/12.5 \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p nguy\u00ean ph\u00e1t<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Lisiplus HCT 10\/12.5<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Hi\u1ec7u qu\u1ea3 h\u1ea1 \u00e1p v\u01b0\u1ee3t tr\u1ed9i c\u1ee7a Lisiplus HCT 10\/12.5 \u0111\u1ebfn t\u1eeb c\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng hi\u1ec7p \u0111\u1ed3ng, b\u1ed5 tr\u1ee3 l\u1eabn nhau c\u1ee7a hai ho\u1ea1t ch\u1ea5t:<\/p>\n<ul>\n<li>Lisinopril: Thu\u1ed9c nh\u00f3m thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n Angiotensin (ACEI). Men chuy\u1ec3n Angiotensin (ACE) l\u00e0 m\u1ed9t enzyme \u0111\u00f3ng vai tr\u00f2 trung t\u00e2m trong h\u1ec7 Renin-Angiotensin-Aldosterone (RAA) \u2013 h\u1ec7 th\u1ed1ng ch\u00ednh \u0111i\u1ec1u h\u00f2a huy\u1ebft \u00e1p c\u1ee7a c\u01a1 th\u1ec3. B\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf ACE, Lisinopril ng\u0103n c\u1ea3n s\u1ef1 chuy\u1ec3n h\u00f3a Angiotensin I (kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh) th\u00e0nh Angiotensin II (m\u1ed9t ch\u1ea5t co m\u1ea1ch c\u1ef1c m\u1ea1nh). K\u1ebft qu\u1ea3 l\u00e0 n\u1ed3ng \u0111\u1ed9 Angiotensin II gi\u1ea3m, g\u00e2y gi\u00e3n m\u1ea1ch m\u00e1u, gi\u1ea3m s\u1ee9c c\u1ea3n ngo\u1ea1i bi\u00ean, t\u1eeb \u0111\u00f3 l\u00e0m h\u1ea1 huy\u1ebft \u00e1p. \u0110\u1ed3ng th\u1eddi, vi\u1ec7c gi\u1ea3m Angiotensin II c\u0169ng l\u00e0m gi\u1ea3m ti\u1ebft Aldosterone, d\u1eabn \u0111\u1ebfn t\u0103ng th\u1ea3i tr\u1eeb natri v\u00e0 n\u01b0\u1edbc, g\u00f3p ph\u1ea7n l\u00e0m gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n v\u00e0 h\u1ea1 \u00e1p.<\/li>\n<li>Hydrochlorothiazide: Thu\u1ed9c nh\u00f3m thu\u1ed1c l\u1ee3i ti\u1ec3u thiazid. Ho\u1ea1t ch\u1ea5t n\u00e0y t\u00e1c \u0111\u1ed9ng ch\u1ee7 y\u1ebfu l\u00ean \u1ed1ng l\u01b0\u1ee3n xa c\u1ee7a th\u1eadn, \u1ee9c ch\u1ebf k\u00eanh \u0111\u1ed3ng v\u1eadn chuy\u1ec3n Na+\/Cl-, l\u00e0m t\u0103ng b\u00e0i ti\u1ebft natri, clorid v\u00e0 n\u01b0\u1edbc qua n\u01b0\u1edbc ti\u1ec3u. \u0110i\u1ec1u n\u00e0y tr\u1ef1c ti\u1ebfp l\u00e0m gi\u1ea3m th\u1ec3 t\u00edch huy\u1ebft t\u01b0\u01a1ng v\u00e0 cung l\u01b0\u1ee3ng tim, d\u1eabn \u0111\u1ebfn hi\u1ec7u qu\u1ea3 h\u1ea1 huy\u1ebft \u00e1p ban \u0111\u1ea7u. V\u1ec1 l\u00e2u d\u00e0i, Hydrochlorothiazide c\u00f2n c\u00f3 th\u1ec3 g\u00e2y gi\u00e3n m\u1ea1ch nh\u1eb9, g\u00f3p ph\u1ea7n duy tr\u00ec hi\u1ec7u qu\u1ea3 ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p.<\/li>\n<\/ul>\n<p>S\u1ef1 hi\u1ec7p \u0111\u1ed3ng: Vi\u1ec7c k\u1ebft h\u1ee3p hai thu\u1ed1c n\u00e0y mang l\u1ea1i l\u1ee3i \u00edch k\u00e9p. Thu\u1ed1c l\u1ee3i ti\u1ec3u Hydrochlorothiazide c\u00f3 th\u1ec3 g\u00e2y ra s\u1ef1 ho\u1ea1t h\u00f3a ph\u1ea3n x\u1ea1 c\u1ee7a h\u1ec7 RAA nh\u01b0 m\u1ed9t c\u01a1 ch\u1ebf b\u00f9 tr\u1eeb, \u0111i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 h\u1ea1 \u00e1p c\u1ee7a n\u00f3 khi d\u00f9ng \u0111\u01a1n \u0111\u1ed9c. Tuy nhi\u00ean, Lisinopril s\u1ebd tr\u1ef1c ti\u1ebfp \u1ee9c ch\u1ebf s\u1ef1 ho\u1ea1t h\u00f3a n\u00e0y. Ng\u01b0\u1ee3c l\u1ea1i, Lisinopril c\u00f3 xu h\u01b0\u1edbng l\u00e0m t\u0103ng nh\u1eb9 n\u1ed3ng \u0111\u1ed9 kali m\u00e1u, trong khi Hydrochlorothiazide l\u1ea1i g\u00e2y m\u1ea5t kali. S\u1ef1 k\u1ebft h\u1ee3p n\u00e0y c\u00f3 th\u1ec3 gi\u00fap c\u00e2n b\u1eb1ng v\u00e0 gi\u1ea3m thi\u1ec3u nguy c\u01a1 r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i kali, m\u1eb7c d\u00f9 vi\u1ec7c theo d\u00f5i n\u1ed3ng \u0111\u1ed9 kali m\u00e1u v\u1eabn l\u00e0 c\u1ea7n thi\u1ebft.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Lisinopril: \u0110\u01b0\u1ee3c h\u1ea5p thu kho\u1ea3ng 25% sau khi u\u1ed1ng v\u00e0 th\u1ee9c \u0103n kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 h\u1ea5p thu. N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau kho\u1ea3ng 7 gi\u1edd. Th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 12,6 gi\u1edd. Thu\u1ed1c kh\u00f4ng b\u1ecb chuy\u1ec3n h\u00f3a v\u00e0 \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua th\u1eadn \u1edf d\u1ea1ng kh\u00f4ng \u0111\u1ed5i.<\/p>\n<p>Hydrochlorothiazide: H\u1ea5p thu t\u01b0\u01a1ng \u0111\u1ed1i nhanh qua \u0111\u01b0\u1eddng u\u1ed1ng. Thu\u1ed1c c\u00f3 hi\u1ec7u l\u1ef1c sau kho\u1ea3ng 2 gi\u1edd, \u0111\u1ea1t \u0111\u1ec9nh sau 4 gi\u1edd v\u00e0 t\u00e1c d\u1ee5ng k\u00e9o d\u00e0i t\u1eeb 6-12 gi\u1edd. Thu\u1ed1c \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb ph\u1ea7n l\u1edbn qua n\u01b0\u1edbc ti\u1ec3u \u1edf d\u1ea1ng kh\u00f4ng \u0111\u1ed5i.<\/p>\n<h2>Thu\u1ed1c Lisiplus HCT 10\/12.5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c Lisiplus HCT 10\/12.5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p nguy\u00ean ph\u00e1t \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 huy\u1ebft \u00e1p kh\u00f4ng \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t t\u1ed1t khi s\u1eed d\u1ee5ng \u0111\u01a1n tr\u1ecb li\u1ec7u b\u1eb1ng Lisinopril ho\u1eb7c Hydrochlorothiazide.<\/p>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Lisiplus HCT 10\/12.5<\/h2>\n<p>Li\u1ec1u d\u00f9ng th\u00f4ng th\u01b0\u1eddng: U\u1ed1ng 1 vi\u00ean\/l\u1ea7n\/ng\u00e0y. N\u00ean u\u1ed1ng thu\u1ed1c v\u00e0o c\u00f9ng m\u1ed9t th\u1eddi \u0111i\u1ec3m c\u1ed1 \u0111\u1ecbnh m\u1ed7i ng\u00e0y \u0111\u1ec3 duy tr\u00ec n\u1ed3ng \u0111\u1ed9 thu\u1ed1c \u1ed5n \u0111\u1ecbnh.<\/p>\n<p>T\u1ed1i \u01b0u h\u00f3a li\u1ec1u: N\u1ebfu huy\u1ebft \u00e1p m\u1ee5c ti\u00eau kh\u00f4ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 2-4 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb, b\u00e1c s\u0129 c\u00f3 th\u1ec3 xem x\u00e9t t\u0103ng li\u1ec1u l\u00ean 2 vi\u00ean\/l\u1ea7n\/ng\u00e0y.<\/p>\n<p>C\u00e1ch d\u00f9ng: D\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng, c\u00f3 th\u1ec3 u\u1ed1ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng b\u1eefa \u0103n.<\/p>\n<p>\u0110\u1ed1i t\u01b0\u1ee3ng \u0111\u1eb7c bi\u1ec7t:<\/p>\n<ul>\n<li>B\u1ec7nh nh\u00e2n suy th\u1eadn: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn n\u1eb7ng. V\u1edbi b\u1ec7nh nh\u00e2n c\u00f3 \u0111\u1ed9 thanh th\u1ea3i creatinin t\u1eeb 30-80 ml\/ph\u00fat, vi\u1ec7c s\u1eed d\u1ee5ng c\u1ea7n \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc c\u1ea9n th\u1eadn v\u00e0 ch\u1ec9 sau khi \u0111\u00e3 d\u00f2 li\u1ec1u ri\u00eang l\u1ebb c\u1ee7a t\u1eebng th\u00e0nh ph\u1ea7n.<\/li>\n<li>B\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng thu\u1ed1c l\u1ee3i ti\u1ec3u: N\u00ean ng\u01b0ng thu\u1ed1c l\u1ee3i ti\u1ec3u 2-3 ng\u00e0y tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u v\u1edbi Lisiplus HCT \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 h\u1ea1 huy\u1ebft \u00e1p qu\u00e1 m\u1ee9c. N\u1ebfu kh\u00f4ng th\u1ec3, b\u00e1c s\u0129 c\u00f3 th\u1ec3 b\u1eaft \u0111\u1ea7u v\u1edbi li\u1ec1u Lisinopril \u0111\u01a1n \u0111\u1ed9c l\u00e0 5mg.<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Lisiplus HCT 10\/12.5 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Qu\u00e1 m\u1eabn v\u1edbi Lisinopril, Hydrochlorothiazide, c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf ACE kh\u00e1c, c\u00e1c d\u1eabn xu\u1ea5t sulfonamid ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>Ti\u1ec1n s\u1eed ph\u00f9 m\u1ea1ch (s\u01b0ng m\u1eb7t, m\u00f4i, l\u01b0\u1ee1i, thanh qu\u1ea3n) do s\u1eed d\u1ee5ng thu\u1ed1c \u1ee9c ch\u1ebf ACE tr\u01b0\u1edbc \u0111\u00f3, ho\u1eb7c ph\u00f9 m\u1ea1ch di truy\u1ec1n\/v\u00f4 c\u0103n.<\/p>\n<p>Suy th\u1eadn n\u1eb7ng (\u0111\u1ed9 thanh th\u1ea3i creatinin &lt; 30 ml\/ph\u00fat), v\u00f4 ni\u1ec7u.<\/p>\n<p>Suy gan n\u1eb7ng.<\/p>\n<p>B\u1ec7nh Gout, t\u0103ng acid uric m\u00e1u, t\u0103ng calci huy\u1ebft kh\u00f4ng ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c.<\/p>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai, \u0111\u1eb7c bi\u1ec7t trong tam c\u00e1 nguy\u1ec7t th\u1ee9 hai v\u00e0 th\u1ee9 ba (3 th\u00e1ng gi\u1eefa v\u00e0 cu\u1ed1i c\u1ee7a thai k\u1ef3).<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Lisiplus HCT 10\/12.5<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Vi\u1ec7c s\u1eed d\u1ee5ng Lisiplus HCT 10\/12.5 \u0111\u00f2i h\u1ecfi s\u1ef1 theo d\u00f5i ch\u1eb7t ch\u1ebd c\u1ee7a b\u00e1c s\u0129, \u0111\u1eb7c bi\u1ec7t v\u1edbi c\u00e1c c\u1ea3nh b\u00e1o quan tr\u1ecdng sau:<\/p>\n<ul>\n<li>Nguy c\u01a1 li\u00ean quan \u0111\u1ebfn Lisinopril:\n<ul>\n<li>Ho khan: \u0110\u00e2y l\u00e0 m\u1ed9t t\u00e1c d\u1ee5ng ph\u1ee5 r\u1ea5t \u0111\u1eb7c tr\u01b0ng c\u1ee7a nh\u00f3m thu\u1ed1c \u1ee9c ch\u1ebf ACE. Ho th\u01b0\u1eddng dai d\u1eb3ng, kh\u00f4ng c\u00f3 \u0111\u1eddm v\u00e0 s\u1ebd h\u1ebft sau khi ng\u01b0ng thu\u1ed1c.<\/li>\n<li>Ph\u00f9 m\u1ea1ch (Angioedema): M\u1eb7c d\u00f9 hi\u1ebfm g\u1eb7p, \u0111\u00e2y l\u00e0 m\u1ed9t ph\u1ea3n \u1ee9ng ph\u1ee5 nghi\u00eam tr\u1ecdng, c\u00f3 th\u1ec3 \u0111e d\u1ecda t\u00ednh m\u1ea1ng. B\u1ea5t k\u1ef3 d\u1ea5u hi\u1ec7u s\u01b0ng m\u1eb7t, m\u00f4i, l\u01b0\u1ee1i, ho\u1eb7c kh\u00f3 th\u1edf n\u00e0o \u0111\u1ec1u c\u1ea7n \u0111\u01b0\u1ee3c c\u1ea5p c\u1ee9u y t\u1ebf ngay l\u1eadp t\u1ee9c v\u00e0 ng\u01b0ng thu\u1ed1c v\u0129nh vi\u1ec5n.<\/li>\n<\/ul>\n<\/li>\n<li>Nguy c\u01a1 li\u00ean quan \u0111\u1ebfn Hydrochlorothiazide:\n<ul>\n<li>R\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i: C\u1ea7n theo d\u00f5i \u0111\u1ecbnh k\u1ef3 n\u1ed3ng \u0111\u1ed9 c\u00e1c ch\u1ea5t \u0111i\u1ec7n gi\u1ea3i trong m\u00e1u. Nguy c\u01a1 h\u1ea1 kali huy\u1ebft, h\u1ea1 natri huy\u1ebft, h\u1ea1 magnesi huy\u1ebft v\u00e0 t\u0103ng calci huy\u1ebft c\u00f3 th\u1ec3 x\u1ea3y ra.<\/li>\n<li>T\u0103ng acid uric: Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng cho b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed b\u1ec7nh Gout v\u00ec thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 acid uric v\u00e0 g\u00e2y ra c\u01a1n gout c\u1ea5p.<\/li>\n<\/ul>\n<\/li>\n<li>Theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn: C\u1ea7n ki\u1ec3m tra n\u1ed3ng \u0111\u1ed9 creatinin v\u00e0 ure m\u00e1u tr\u01b0\u1edbc khi \u0111i\u1ec1u tr\u1ecb v\u00e0 \u0111\u1ecbnh k\u1ef3 trong qu\u00e1 tr\u00ecnh s\u1eed d\u1ee5ng, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 suy th\u1eadn (h\u1eb9p \u0111\u1ed9ng m\u1ea1ch th\u1eadn, suy tim, ng\u01b0\u1eddi cao tu\u1ed5i).<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p: Ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, ho khan (do Lisinopril), m\u1ec7t m\u1ecfi, h\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf \u0111\u1ee9ng.<\/p>\n<p>\u00cdt g\u1eb7p: R\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a (bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y), ph\u00e1t ban da, y\u1ebfu c\u01a1, chu\u1ed9t r\u00fat.<\/p>\n<p>Hi\u1ebfm g\u1eb7p: Ph\u00f9 m\u1ea1ch, vi\u00eam t\u1ee5y, r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng gan, thay \u0111\u1ed5i c\u00f4ng th\u1ee9c m\u00e1u.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Lisiplus HCT c\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi nhi\u1ec1u lo\u1ea1i thu\u1ed1c kh\u00e1c. Th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 v\u1ec1 t\u1ea5t c\u1ea3 c\u00e1c lo\u1ea1i thu\u1ed1c b\u1ea1n \u0111ang d\u00f9ng, \u0111\u1eb7c bi\u1ec7t l\u00e0:<\/p>\n<ul>\n<li>Thu\u1ed1c l\u1ee3i ti\u1ec3u gi\u1eef kali, vi\u00ean u\u1ed1ng b\u1ed5 sung kali.<\/li>\n<li>Thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid (NSAIDs).<\/li>\n<li>Lithi.<\/li>\n<li>C\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng (Insulin, thu\u1ed1c u\u1ed1ng).<\/li>\n<li>C\u00e1c thu\u1ed1c h\u1ea1 huy\u1ebft \u00e1p kh\u00e1c.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh tuy\u1ec7t \u0111\u1ed1i s\u1eed d\u1ee5ng Lisiplus HCT trong tam c\u00e1 nguy\u1ec7t th\u1ee9 hai v\u00e0 th\u1ee9 ba c\u1ee7a thai k\u1ef3. C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf ACE nh\u01b0 Lisinopril c\u00f3 th\u1ec3 g\u00e2y t\u1ed5n th\u01b0\u01a1ng nghi\u00eam tr\u1ecdng, th\u1eadm ch\u00ed g\u00e2y t\u1eed vong cho thai nhi (suy th\u1eadn, thi\u1ec3u \u1ed1i, ch\u1eadm c\u1ed1t h\u00f3a x\u01b0\u01a1ng s\u1ecd). Ph\u1ea3i ng\u01b0ng thu\u1ed1c ngay khi ph\u00e1t hi\u1ec7n c\u00f3 thai.<\/p>\n<p>Ph\u1ee5 n\u1eef cho con b\u00fa: Kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng do c\u1ea3 Lisinopril v\u00e0 Hydrochlorothiazide \u0111\u1ec1u c\u00f3 th\u1ec3 b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ch\u00f3ng m\u1eb7t, m\u1ec7t m\u1ecfi, \u0111\u1eb7c bi\u1ec7t khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb ho\u1eb7c thay \u0111\u1ed5i li\u1ec1u. C\u1ea7n th\u1eadn tr\u1ecdng khi l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c cho \u0111\u1ebfn khi x\u00e1c \u0111\u1ecbnh r\u00f5 thu\u1ed1c kh\u00f4ng \u1ea3nh h\u01b0\u1edfng ti\u00eau c\u1ef1c \u0111\u1ebfn kh\u1ea3 n\u0103ng c\u1ee7a b\u1ea1n.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>C\u1ea7n \u0111\u01b0a b\u1ec7nh nh\u00e2n \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf g\u1ea7n nh\u1ea5t. Bi\u1ec7n ph\u00e1p x\u1eed tr\u00ed ch\u1ee7 y\u1ebfu l\u00e0 truy\u1ec1n t\u0129nh m\u1ea1ch dung d\u1ecbch mu\u1ed1i sinh l\u00fd \u0111\u1ec3 n\u00e2ng huy\u1ebft \u00e1p.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n Lisiplus HCT 10\/12.5 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t, nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30\u00b0C, tr\u00e1nh \u00e1nh s\u00e1ng tr\u1ef1c ti\u1ebfp v\u00e0 t\u1ea7m tay tr\u1ebb em.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Lisiplus HCT 10\/12.5<\/h2>\n<p><a href=\"https:\/\/vnras.com\/drug\/umenohct-20-125\/\">UmenoHCT 20\/12,5<\/a> l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t t\u1ea1i Vi\u1ec7t Nam b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m SaVi, v\u1edbi s\u1ef1 k\u1ebft h\u1ee3p c\u1ee7a hai ho\u1ea1t ch\u1ea5t l\u00e0 Lisinopril 20mg v\u00e0 Hydroclorothiazid 12,5mg.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Aziz Sukalo, Dervis Deljo. Treatment of Hypertension with Combination of Lisinopril\/Hydrochlorothiazide, truy c\u1eadp ng\u00e0y 13 th\u00e1ng 09 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27703294\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/27703294\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>S\u1ea3n ph\u1ea9m thu\u1ed1c Lisiplus HCT 10\/12.5 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean Doanh Stellapharm &#8211; Chi nh\u00e1nh 1, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-17766-12, \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p nguy\u00ean ph\u00e1t.<\/p>\n","protected":false},"author":1,"featured_media":138684,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-138682","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/138682","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=138682"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/138684"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=138682"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=138682"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=138682"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}