{"id":138438,"date":"2025-09-12T14:07:24","date_gmt":"2025-09-12T07:07:24","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=138438"},"modified":"2025-09-12T14:08:48","modified_gmt":"2025-09-12T07:08:48","slug":"tacroz-0-03","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/tacroz-0-03\/","title":{"rendered":"Tacroz 0.03%"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Tacroz 0.03% \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Glenmark Pharmaceuticals Ltd., c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-18320-14.<\/strong><\/p>\n<h2>Tacroz 0.03% l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Tacroz 0.03%<\/strong> l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c m\u1ee1 b\u00f4i ngo\u00e0i da, c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t:<strong> Tacrolimus <\/strong>03% kl\/kl.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: Parafin tr\u1eafng m\u1ec1m, paraffin l\u1ecfng, s\u00e1p ong tr\u1eafng, parafin r\u1eafn, Propylene Carbonate.<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-18320-14<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Thu\u1ed1c m\u1ee1 b\u00f4i ngo\u00e0i da<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 tu\u00fdp 10 g<\/p>\n<p>Xu\u1ea5t x\u1ee9: India<\/p>\n<figure id=\"attachment_138443\" aria-describedby=\"caption-attachment-138443\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-138443\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Tacroz-0.03.jpg\" alt=\"Tacroz 0.03% \u0111i\u1ec1u tr\u1ecb vi\u00eam da d\u1ecb \u1ee9ng v\u1eeba v\u00e0 n\u1eb7ng\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Tacroz-0.03.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Tacroz-0.03-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Tacroz-0.03-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Tacroz-0.03-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Tacroz-0.03-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-138443\" class=\"wp-caption-text\">Tacroz 0.03% \u0111i\u1ec1u tr\u1ecb vi\u00eam da d\u1ecb \u1ee9ng v\u1eeba v\u00e0 n\u1eb7ng<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Tacroz 0.03%<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a Tacrolimus trong \u0111i\u1ec1u tr\u1ecb vi\u00eam da c\u01a1 \u0111\u1ecba r\u1ea5t \u0111\u1eb7c hi\u1ec7u v\u00e0 l\u00e0 m\u1ed9t b\u01b0\u1edbc ti\u1ebfn trong ng\u00e0nh d\u01b0\u1ee3c l\u00fd da li\u1ec5u. Ho\u1ea1t ch\u1ea5t n\u00e0y t\u00e1c \u0111\u1ed9ng s\u00e2u v\u00e0o chu\u1ed7i ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch g\u00e2y ra t\u00ecnh tr\u1ea1ng vi\u00eam da:<\/p>\n<ul>\n<li>G\u1eafn k\u1ebft v\u1edbi Protein n\u1ed9i b\u00e0o: Khi \u0111\u01b0\u1ee3c b\u00f4i l\u00ean da, Tacrolimus s\u1ebd th\u1ea5m v\u00e0o c\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch, ch\u1ee7 y\u1ebfu l\u00e0 t\u1ebf b\u00e0o lympho T. T\u1ea1i \u0111\u00e2y, n\u00f3 g\u1eafn v\u00e0o m\u1ed9t protein n\u1ed9i b\u00e0o c\u00f3 t\u00ean l\u00e0 FKBP-12.<\/li>\n<li>\u1ee8c ch\u1ebf Calcineurin: Ph\u1ee9c h\u1ee3p Tacrolimus-FKBP12 sau \u0111\u00f3 h\u00ecnh th\u00e0nh s\u1ebd li\u00ean k\u1ebft v\u00e0 \u1ee9c ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a calcineurin, m\u1ed9t enzyme phosphatase ph\u1ee5 thu\u1ed9c canxi.<\/li>\n<li>Ng\u0103n ch\u1eb7n ho\u1ea1t h\u00f3a t\u1ebf b\u00e0o T: Calcineurin \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong vi\u1ec7c k\u00edch ho\u1ea1t y\u1ebfu t\u1ed1 phi\u00ean m\u00e3 NFAT (Nuclear Factor of Activated T-cells). B\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf calcineurin, Tacrolimus ng\u0103n ch\u1eb7n qu\u00e1 tr\u00ecnh dephosphoryl h\u00f3a v\u00e0 di chuy\u1ec3n c\u1ee7a NFAT v\u00e0o nh\u00e2n t\u1ebf b\u00e0o. \u0110i\u1ec1u n\u00e0y l\u00e0m gi\u00e1n \u0111o\u1ea1n qu\u00e1 tr\u00ecnh phi\u00ean m\u00e3 gen c\u1ee7a c\u00e1c cytokine g\u00e2y vi\u00eam.<\/li>\n<li>Gi\u1ea3m gi\u1ea3i ph\u00f3ng Cytokine: K\u1ebft qu\u1ea3 cu\u1ed1i c\u00f9ng l\u00e0 s\u1ef1 s\u1ea3n xu\u1ea5t c\u00e1c cytokine ti\u1ec1n vi\u00eam nh\u01b0 Interleukin-2 (IL-2), IL-3, IL-4, IL-5, Interferon-gamma (IFN-\u03b3), v\u00e0 TNF-\u03b1 b\u1ecb \u1ee9c ch\u1ebf m\u1ea1nh m\u1ebd. \u0110\u00e2y ch\u00ednh l\u00e0 c\u00e1c &#8220;s\u1ee9 gi\u1ea3 h\u00f3a h\u1ecdc&#8221; g\u00e2y ra ph\u1ea3n \u1ee9ng vi\u00eam, \u0111\u1ecf v\u00e0 ng\u1ee9a \u1edf da.<\/li>\n<\/ul>\n<p>N\u00f3i m\u1ed9t c\u00e1ch \u0111\u01a1n gi\u1ea3n, Tacroz 0.03% &#8220;l\u00e0m d\u1ecbu&#8221; ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch qu\u00e1 m\u1ee9c t\u1ea1i v\u00f9ng da b\u1ecb b\u1ec7nh, c\u1eaft \u0111\u1ee9t v\u00f2ng xo\u1eafn b\u1ec7nh l\u00fd &#8220;ng\u1ee9a &#8211; g\u00e3i &#8211; vi\u00eam&#8221; c\u1ee7a b\u1ec7nh ch\u00e0m m\u00e0 kh\u00f4ng c\u1ea7n \u0111\u1ebfn corticosteroid.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>M\u1ed9t trong nh\u1eefng \u01b0u \u0111i\u1ec3m l\u1edbn nh\u1ea5t c\u1ee7a Tacrolimus khi d\u00f9ng t\u1ea1i ch\u1ed7 l\u00e0 s\u1ef1 h\u1ea5p thu to\u00e0n th\u00e2n (v\u00e0o m\u00e1u) r\u1ea5t th\u1ea5p ho\u1eb7c kh\u00f4ng \u0111\u00e1ng k\u1ec3. C\u00e1c nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng \u0111\u00e3 ch\u1ec9 ra r\u1eb1ng sau khi b\u00f4i thu\u1ed1c m\u1ee1 Tacrolimus, n\u1ed3ng \u0111\u1ed9 ho\u1ea1t ch\u1ea5t trong m\u00e1u th\u01b0\u1eddng \u1edf d\u01b0\u1edbi ng\u01b0\u1ee1ng ph\u00e1t hi\u1ec7n ho\u1eb7c r\u1ea5t th\u1ea5p. Sinh kh\u1ea3 d\u1ee5ng c\u1ee7a thu\u1ed1c qua da \u0111\u01b0\u1ee3c \u01b0\u1edbc t\u00ednh l\u00e0 d\u01b0\u1edbi 0.5%. \u0110i\u1ec1u n\u00e0y c\u00f3 ngh\u0129a l\u00e0 thu\u1ed1c ch\u1ee7 y\u1ebfu t\u00e1c \u0111\u1ed9ng t\u1ea1i ch\u1ed7 tr\u00ean da, gi\u1ea3m thi\u1ec3u nguy c\u01a1 g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 to\u00e0n th\u00e2n so v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch \u0111\u01b0\u1eddng u\u1ed1ng.<\/p>\n<h2>Thu\u1ed1c Tacroz 0.03% \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c m\u1ee1 Tacrolimus \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb ng\u1eafn h\u1ea1n ho\u1eb7c d\u00e0i h\u1ea1n ng\u1eaft qu\u00e3ng cho b\u1ec7nh nh\u00e2n b\u1ecb vi\u00eam da c\u01a1 \u0111\u1ecba (ch\u00e0m) t\u1eeb th\u1ec3 trung b\u00ecnh \u0111\u1ebfn n\u1eb7ng.<\/p>\n<p>Ch\u1ec9 \u0111\u1ecbnh n\u00e0y kh\u00f4ng ph\u1ea3i l\u00e0 l\u1ef1a ch\u1ecdn \u0111\u1ea7u tay m\u00e0 d\u00e0nh cho nh\u1eefng tr\u01b0\u1eddng h\u1ee3p:<\/p>\n<ul>\n<li>B\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u00e1p \u1ee9ng \u0111\u1ea7y \u0111\u1ee7 v\u1edbi c\u00e1c li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb truy\u1ec1n th\u1ed1ng (nh\u01b0 corticosteroid b\u00f4i t\u1ea1i ch\u1ed7).<\/li>\n<li>B\u1ec7nh nh\u00e2n kh\u00f4ng dung n\u1ea1p \u0111\u01b0\u1ee3c c\u00e1c li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb truy\u1ec1n th\u1ed1ng.<\/li>\n<li>Vi\u1ec7c s\u1eed d\u1ee5ng c\u00e1c li\u1ec7u ph\u00e1p truy\u1ec1n th\u1ed1ng kh\u00f4ng th\u00edch h\u1ee3p v\u00ec c\u00e1c nguy c\u01a1 ti\u1ec1m t\u00e0ng.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Tacroz 0.03%<\/h2>\n<p>Ng\u01b0\u1eddi l\u1edbn (t\u1eeb 16 tu\u1ed5i tr\u1edf l\u00ean): C\u00f3 th\u1ec3 b\u1eaft \u0111\u1ea7u v\u1edbi n\u1ed3ng \u0111\u1ed9 0.1% ho\u1eb7c 0.03% t\u00f9y v\u00e0o t\u00ecnh tr\u1ea1ng l\u00e2m s\u00e0ng, b\u00f4i 2 l\u1ea7n m\u1ed7i ng\u00e0y.<\/p>\n<p>Tr\u1ebb em (t\u1eeb 2 \u0111\u1ebfn 15 tu\u1ed5i): Ch\u1ec9 s\u1eed d\u1ee5ng thu\u1ed1c m\u1ee1 Tacrolimus 0.03%, b\u00f4i 2 l\u1ea7n m\u1ed7i ng\u00e0y.<\/p>\n<p>L\u01b0u \u00fd: Thu\u1ed1c kh\u00f4ng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho tr\u1ebb em d\u01b0\u1edbi 2 tu\u1ed5i.<\/p>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Tacroz 0.03%<\/h2>\n<p>R\u1eeda s\u1ea1ch v\u00e0 lau kh\u00f4 ho\u00e0n to\u00e0n v\u00f9ng da c\u1ea7n \u0111i\u1ec1u tr\u1ecb tr\u01b0\u1edbc khi b\u00f4i thu\u1ed1c.<\/p>\n<p>L\u1ea5y m\u1ed9t l\u01b0\u1ee3ng thu\u1ed1c v\u1eeba \u0111\u1ee7 v\u00e0 b\u00f4i m\u1ed9t l\u1edbp m\u1ecfng l\u00ean v\u00f9ng da b\u1ecb \u1ea3nh h\u01b0\u1edfng.<\/p>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c b\u00f4i tr\u00ean h\u1ea7u h\u1ebft c\u00e1c v\u00f9ng da c\u1ee7a c\u01a1 th\u1ec3, bao g\u1ed3m m\u1eb7t, c\u1ed5 v\u00e0 c\u00e1c n\u1ebfp g\u1ea5p, nh\u01b0ng tr\u00e1nh \u0111\u1ec3 thu\u1ed1c ti\u1ebfp x\u00fac v\u1edbi ni\u00eam m\u1ea1c (m\u1eaft, mi\u1ec7ng).<\/p>\n<p>R\u1eeda tay s\u1ea1ch sau khi b\u00f4i thu\u1ed1c (tr\u1eeb khi tay l\u00e0 v\u00f9ng da c\u1ea7n \u0111i\u1ec1u tr\u1ecb).<\/p>\n<p>Tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng b\u0103ng k\u00edn v\u00f9ng da sau khi b\u00f4i thu\u1ed1c, v\u00ec \u0111i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 l\u00e0m t\u0103ng s\u1ef1 h\u1ea5p thu to\u00e0n th\u00e2n c\u1ee7a thu\u1ed1c.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Tacroz 0.03% trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Thu\u1ed1c Tacroz 0.03% ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed m\u1eabn c\u1ea3m ho\u1eb7c d\u1ecb \u1ee9ng v\u1edbi Tacrolimus hay b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a t\u00e1 d\u01b0\u1ee3c.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Tacroz 0.03%<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>\u0110\u00e2y l\u00e0 l\u01b0u \u00fd quan tr\u1ecdng nh\u1ea5t. M\u1eb7c d\u00f9 hi\u1ebfm g\u1eb7p v\u00e0 m\u1ed1i quan h\u1ec7 nh\u00e2n qu\u1ea3 ch\u01b0a \u0111\u01b0\u1ee3c thi\u1ebft l\u1eadp r\u00f5 r\u00e0ng, C\u1ee5c qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3 (FDA) \u0111\u00e3 \u0111\u01b0a ra c\u1ea3nh b\u00e1o v\u1ec1 nguy c\u01a1 l\u00fd thuy\u1ebft li\u00ean quan \u0111\u1ebfn ung th\u01b0 da (kh\u00f4ng ph\u1ea3i u h\u1eafc t\u1ed1) v\u00e0 u lympho khi s\u1eed d\u1ee5ng c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf calcineurin t\u1ea1i ch\u1ed7 trong th\u1eddi gian d\u00e0i. C\u1ea3nh b\u00e1o n\u00e0y d\u1ef1a tr\u00ean c\u00e1c b\u00e1o c\u00e1o ca b\u1ec7nh sau khi thu\u1ed1c ra th\u1ecb tr\u01b0\u1eddng v\u00e0 d\u1eef li\u1ec7u t\u1eeb c\u00e1c nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt khi d\u00f9ng li\u1ec1u cao to\u00e0n th\u00e2n. Do \u0111\u00f3, thu\u1ed1c ch\u1ec9 n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u00fang theo ch\u1ec9 \u0111\u1ecbnh, kh\u00f4ng n\u00ean d\u00f9ng li\u00ean t\u1ee5c k\u00e9o d\u00e0i v\u00e0 n\u00ean h\u1ea1n ch\u1ebf t\u1ed1i \u0111a vi\u1ec7c ti\u1ebfp x\u00fac v\u1edbi \u00e1nh s\u00e1ng m\u1eb7t tr\u1eddi t\u1ef1 nhi\u00ean hay nh\u00e2n t\u1ea1o (nh\u01b0 gi\u01b0\u1eddng t\u1eafm n\u1eafng) trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Nhi\u1ec5m khu\u1ea9n da: Kh\u00f4ng n\u00ean b\u00f4i thu\u1ed1c l\u00ean v\u00f9ng da \u0111ang b\u1ecb nhi\u1ec5m khu\u1ea9n c\u1ea5p t\u00ednh. N\u1ebfu c\u00f3 d\u1ea5u hi\u1ec7u nhi\u1ec5m tr\u00f9ng, c\u1ea7n \u0111i\u1ec1u tr\u1ecb kh\u1ecfi tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u s\u1eed d\u1ee5ng Tacroz. Vi\u1ec7c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Tacrolimus c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m virus Herpes simplex ho\u1eb7c Varicella zoster (th\u1ee7y \u0111\u1eadu, zona).<\/p>\n<p>B\u1ec7nh h\u1ea1ch b\u1ea1ch huy\u1ebft: N\u1ebfu b\u1ec7nh nh\u00e2n c\u00f3 s\u01b0ng h\u1ea1ch trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, c\u1ea7n ph\u1ea3i \u0111\u01b0\u1ee3c b\u00e1c s\u0129 th\u0103m kh\u00e1m \u0111\u1ec3 t\u00ecm ra nguy\u00ean nh\u00e2n.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>R\u1ea5t ph\u1ed5 bi\u1ebfn: C\u00e1c ph\u1ea3n \u1ee9ng t\u1ea1i ch\u1ed7 b\u00f4i l\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p nh\u1ea5t, \u0111\u1eb7c bi\u1ec7t trong v\u00e0i ng\u00e0y \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb. Ch\u00fang bao g\u1ed3m c\u1ea3m gi\u00e1c n\u00f3ng r\u00e1t, ch\u00e2m ch\u00edch, ng\u1ee9a v\u00e0 \u0111\u1ecf da. C\u00e1c tri\u1ec7u ch\u1ee9ng n\u00e0y th\u01b0\u1eddng \u1edf m\u1ee9c \u0111\u1ed9 nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh v\u00e0 s\u1ebd gi\u1ea3m d\u1ea7n khi t\u00ecnh tr\u1ea1ng vi\u00eam da \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n.<\/p>\n<p>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00e1c: Vi\u00eam nang l\u00f4ng, m\u1ee5n tr\u1ee9ng c\u00e1, t\u0103ng nh\u1ea1y c\u1ea3m da (\u0111\u1eb7c bi\u1ec7t v\u1edbi n\u00f3ng v\u00e0 l\u1ea1nh), v\u00e0 kh\u00f4ng dung n\u1ea1p r\u01b0\u1ee3u (\u0111\u1ecf b\u1eebng m\u1eb7t ho\u1eb7c k\u00edch \u1ee9ng da sau khi u\u1ed1ng \u0111\u1ed3 u\u1ed1ng c\u00f3 c\u1ed3n) c\u0169ng \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Do h\u1ea5p thu to\u00e0n th\u00e2n r\u1ea5t \u00edt, t\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c l\u00e0 hi\u1ebfm g\u1eb7p. Tuy nhi\u00ean, c\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf m\u1ea1nh men gan CYP3A4 (nh\u01b0 kh\u00e1ng sinh nh\u00f3m macrolid, kh\u00e1ng n\u1ea5m nh\u00f3m azole) tr\u00ean nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 di\u1ec7n t\u00edch b\u00f4i thu\u1ed1c r\u1ed9ng ho\u1eb7c b\u1ecb ch\u1ee9ng \u0111\u1ecf da to\u00e0n th\u00e2n.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai: Ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u v\u1ec1 t\u00ednh an to\u00e0n. Ch\u1ec9 s\u1eed d\u1ee5ng thu\u1ed1c khi l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1 v\u00e0 c\u00f3 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129.<\/p>\n<p>B\u00e0 m\u1eb9 cho con b\u00fa: Tacrolimus c\u00f3 b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9. C\u1ea7n c\u00e2n nh\u1eafc gi\u1eefa vi\u1ec7c ng\u01b0ng cho con b\u00fa ho\u1eb7c ng\u01b0ng d\u00f9ng thu\u1ed1c, t\u00f9y thu\u1ed9c v\u00e0o t\u1ea7m quan tr\u1ecdng c\u1ee7a thu\u1ed1c \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi m\u1eb9.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Qu\u00e1 li\u1ec1u khi d\u00f9ng t\u1ea1i ch\u1ed7 l\u00e0 r\u1ea5t kh\u00f3 x\u1ea3y ra. Thu\u1ed1c kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng. N\u1ebfu v\u00f4 t\u00ecnh nu\u1ed1t ph\u1ea3i, c\u1ea7n \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf ngay l\u1eadp t\u1ee9c \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n thu\u1ed1c \u1edf nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30\u00b0C, kh\u00f4ng \u0111\u1ec3 \u0111\u00f4ng l\u1ea1nh. \u0110\u1ec3 xa t\u1ea7m tay tr\u1ebb em. Sau khi m\u1edf n\u1eafp, thu\u1ed1c ch\u1ec9 n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong v\u00f2ng 3 th\u00e1ng.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Tacroz 0.03%<\/h2>\n<p>Tr\u00ean th\u1ecb tr\u01b0\u1eddng c\u00f3 m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c c\u0169ng ch\u1ee9a ho\u1ea1t ch\u1ea5t Tacrolimus 0.03%, trong \u0111\u00f3 c\u00f3 thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/quantopic-003\/\">Quantopic 0.03%<\/a>. \u0110\u00e2y l\u00e0 s\u1ea3n ph\u1ea9m c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t, n\u1ed3ng \u0111\u1ed9 v\u00e0 d\u1ea1ng b\u00e0o ch\u1ebf, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng v\u1edbi ch\u1ec9 \u0111\u1ecbnh t\u01b0\u01a1ng t\u1ef1 nh\u01b0 Tacroz 0.03%.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Shinji Uemoto. Tacrolimus, truy c\u1eadp ng\u00e0y 12 th\u00e1ng 09 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15954428\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/15954428\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>S\u1ea3n ph\u1ea9m thu\u1ed1c Tacroz 0.03% \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Glenmark Pharmaceuticals Ltd., c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-18320-14, \u0111i\u1ec1u tr\u1ecb vi\u00eam da c\u01a1 \u0111\u1ecba (ch\u00e0m) trung b\u00ecnh \u0111\u1ebfn n\u1eb7ng.<\/p>\n","protected":false},"author":1,"featured_media":138439,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-138438","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/138438","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=138438"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/138439"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=138438"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=138438"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=138438"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}