{"id":137839,"date":"2025-09-09T21:55:16","date_gmt":"2025-09-09T14:55:16","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=137839"},"modified":"2025-09-11T16:29:55","modified_gmt":"2025-09-11T09:29:55","slug":"zoamco-a","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/zoamco-a\/","title":{"rendered":"Zoamco-A"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <a href=\"https:\/\/vnras.com\/drug\/\">d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Zoamco-A \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n Pymepharco c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-36187-22<\/strong><\/p>\n<h2>Zoamco-A l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ng Zoamco-A<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Amlodipin besylat t\u01b0\u01a1ng \u1ee9ng v\u1edbi Amlodipin 5 mg<\/li>\n<li>Atorvastatin calci t\u01b0\u01a1ng \u1ee9ng v\u1edbi Atorvastatin 10 mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c g\u1ed3m: Microcrystalline cellulose, Calci carbonat, Tinh b\u1ed9t ti\u1ec1n gelatin h\u00f3a, Hydroxypropyl cellulose, Colloidal silicon dioxid, Magnesi stearat, Hydroxypropylmethylcellulose, PEG 6000, B\u1ed9t talc, Titan dioxid.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-36187-22<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 2 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Zoamco-A<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Amlodipin: L\u00e0 m\u1ed9t thu\u1ed1c ch\u1eb9n k\u00eanh calci thu\u1ed9c nh\u00f3m dihydropyridin. Thu\u1ed1c \u1ee9c ch\u1ebf d\u00f2ng ion calci \u0111i qua m\u00e0ng t\u1ebf b\u00e0o c\u01a1 tr\u01a1n m\u1ea1ch m\u00e1u, l\u00e0m gi\u00e3n m\u1ea1ch ngo\u1ea1i bi\u00ean, t\u1eeb \u0111\u00f3 h\u1ea1 huy\u1ebft \u00e1p. Ngo\u00e0i ra, Amlodipin gi\u00fap c\u1ea3i thi\u1ec7n l\u01b0u l\u01b0\u1ee3ng m\u00e1u t\u1edbi c\u01a1 tim, gi\u1ea3m g\u00e1nh n\u1eb7ng tim v\u00e0 c\u00f3 t\u00e1c d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb \u0111au th\u1eaft ng\u1ef1c. Thu\u1ed1c kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn chuy\u1ec3n h\u00f3a lipid hay \u0111\u01b0\u1eddng huy\u1ebft, n\u00ean c\u00f3 th\u1ec3 d\u00f9ng cho ng\u01b0\u1eddi b\u1ecb t\u0103ng huy\u1ebft \u00e1p k\u00e8m \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng.<\/p>\n<p>Atorvastatin: L\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc enzym HMG-CoA reductase \u2013 m\u1ed9t m\u1eaft x\u00edch quan tr\u1ecdng trong qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p cholesterol. Atorvastatin l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 cholesterol to\u00e0n ph\u1ea7n v\u00e0 LDL-C trong m\u00e1u b\u1eb1ng c\u00e1ch gi\u1ea3m t\u1ed5ng h\u1ee3p cholesterol t\u1ea1i gan, \u0111\u1ed3ng th\u1eddi t\u0103ng s\u1ed1 l\u01b0\u1ee3ng th\u1ee5 th\u1ec3 LDL tr\u00ean b\u1ec1 m\u1eb7t t\u1ebf b\u00e0o gan \u0111\u1ec3 t\u0103ng c\u01b0\u1eddng \u0111\u00e0o th\u1ea3i LDL kh\u1ecfi tu\u1ea7n ho\u00e0n. Thu\u1ed1c gi\u00fap ki\u1ec3m so\u00e1t r\u1ed1i lo\u1ea1n lipid m\u00e1u v\u00e0 l\u00e0m gi\u1ea3m nguy c\u01a1 bi\u1ebfn c\u1ed1 tim m\u1ea1ch.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p><em><strong>Amlodipin:<\/strong><\/em> Sau khi u\u1ed1ng, thu\u1ed1c h\u1ea5p thu ch\u1eadm v\u1edbi n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh \u0111\u1ea1t sau 6\u201312 gi\u1edd, sinh kh\u1ea3 d\u1ee5ng kho\u1ea3ng 60\u201380% v\u00e0 kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi th\u1ee9c \u0103n. Thu\u1ed1c g\u1eafn protein huy\u1ebft t\u01b0\u01a1ng cao (98%), th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 kho\u1ea3ng 21 L\/kg. Th\u1eddi gian b\u00e1n th\u1ea3i d\u00e0i (30\u201340 gi\u1edd), do \u0111\u00f3 ch\u1ec9 c\u1ea7n d\u00f9ng 1 l\u1ea7n\/ng\u00e0y. Amlodipin \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a \u1edf gan th\u00e0nh c\u00e1c ch\u1ea5t kh\u00f4ng c\u00f2n ho\u1ea1t t\u00ednh, \u0111\u00e0o th\u1ea3i ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u. \u1ede b\u1ec7nh nh\u00e2n suy gan, th\u1eddi gian b\u00e1n th\u1ea3i t\u0103ng, v\u00ec v\u1eady c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u.<\/p>\n<p><em><strong>Atorvastatin:<\/strong> <\/em>H\u1ea5p thu nhanh qua \u0111\u01b0\u1eddng u\u1ed1ng, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t sau 1\u20132 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i kho\u1ea3ng 14%, kh\u1ea3 d\u1ee5ng to\u00e0n th\u00e2n t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf men HMG-CoA reductase kho\u1ea3ng 30%. Thu\u1ed1c g\u1eafn v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng &gt;98%, th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 trung b\u00ecnh 38 L. Atorvastatin \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu t\u1ea1i gan th\u00e0nh c\u00e1c ch\u1ea5t hydroxyl h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh. Th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua m\u1eadt sau khi chuy\u1ec3n h\u00f3a, \u00edt th\u1ea3i qua th\u1eadn (&lt;2%). Th\u1eddi gian b\u00e1n th\u1ea3i trung b\u00ecnh 14 gi\u1edd, nh\u01b0ng t\u00e1c d\u1ee5ng h\u1ea1 lipid k\u00e9o d\u00e0i h\u01a1n (10\u201320 gi\u1edd) nh\u1edd c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a ho\u1ea1t t\u00ednh.<\/p>\n<h2>Thu\u1ed1c Zoamco-A \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Zoamco-A \u0111\u01b0\u1ee3c d\u00f9ng cho b\u1ec7nh nh\u00e2n c\u1ea7n ph\u1ed1i h\u1ee3p \u0111i\u1ec1u tr\u1ecb b\u1eb1ng c\u1ea3 Amlodipin v\u00e0 Atorvastatin, c\u1ee5 th\u1ec3:<\/p>\n<p><em><strong>Amlodipin<\/strong><\/em><\/p>\n<p>\u0110i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p, k\u1ec3 c\u1ea3 \u1edf ng\u01b0\u1eddi c\u00f3 k\u00e8m \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, v\u00e0 d\u1ef1 ph\u00f2ng \u0111au th\u1eaft ng\u1ef1c \u1ed5n \u0111\u1ecbnh.<\/p>\n<p><em><strong>Atorvastatin<\/strong><\/em><\/p>\n<p>Ph\u00f2ng ng\u1eeba ti\u00ean ph\u00e1t bi\u1ebfn c\u1ed1 m\u1ea1ch v\u00e0nh \u1edf ng\u01b0\u1eddi t\u0103ng cholesterol m\u00e1u nh\u01b0ng ch\u01b0a c\u00f3 tri\u1ec7u ch\u1ee9ng r\u00f5 r\u1ec7t c\u1ee7a b\u1ec7nh m\u1ea1ch v\u00e0nh, nh\u1eb1m gi\u1ea3m nguy c\u01a1 nh\u1ed3i m\u00e1u c\u01a1 tim, t\u1eed vong do tim m\u1ea1ch v\u00e0 nhu c\u1ea7u t\u00e1i th\u00f4ng m\u1ea1ch v\u00e0nh.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch \u1edf b\u1ec7nh nh\u00e2n t\u0103ng cholesterol m\u00e1u k\u00e8m b\u1ec7nh m\u1ea1ch v\u00e0nh l\u00e2m s\u00e0ng (k\u1ec3 c\u1ea3 ti\u1ec1n s\u1eed nh\u1ed3i m\u00e1u c\u01a1 tim), gi\u00fap l\u00e0m ch\u1eadm ti\u1ebfn tri\u1ec3n x\u01a1 v\u1eefa v\u00e0 h\u1ea1n ch\u1ebf bi\u1ebfn c\u1ed1 m\u1ea1ch v\u00e0nh c\u1ea5p.<\/p>\n<figure id=\"attachment_137854\" aria-describedby=\"caption-attachment-137854\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-137854\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Zoamco-A.jpg\" alt=\"Zoamco-A\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Zoamco-A.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Zoamco-A-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Zoamco-A-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Zoamco-A-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Zoamco-A-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-137854\" class=\"wp-caption-text\">Thu\u1ed1c Zoamco-A c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb k\u1ebft h\u1ee3p c\u1ea3 t\u0103ng huy\u1ebft \u00e1p, \u0111au th\u1eaft ng\u1ef1c v\u00e0 r\u1ed1i lo\u1ea1n lipid m\u00e1u.<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Amlodipin: Li\u1ec1u kh\u1edfi \u0111\u1ea7u th\u00f4ng th\u01b0\u1eddng l\u00e0 5 mg\/l\u1ea7n\/ng\u00e0y. C\u00f3 th\u1ec3 t\u0103ng li\u1ec1u l\u00ean t\u1ed1i \u0111a 10 mg\/ng\u00e0y t\u00f9y theo \u0111\u00e1p \u1ee9ng c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh. N\u1ebfu sau 4 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb ch\u01b0a \u0111\u1ea1t hi\u1ec7u qu\u1ea3, c\u00e2n nh\u1eafc t\u0103ng li\u1ec1u.<\/p>\n<p>Atorvastatin: Kh\u1edfi \u0111\u1ea7u th\u01b0\u1eddng t\u1eeb 10 mg\/l\u1ea7n\/ng\u00e0y. C\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u sau m\u1ed7i 4 tu\u1ea7n, d\u1ef1a tr\u00ean \u0111\u00e1p \u1ee9ng v\u00e0 kh\u1ea3 n\u0103ng dung n\u1ea1p, v\u1edbi li\u1ec1u duy tr\u00ec 10\u201340 mg\/ng\u00e0y. Li\u1ec1u t\u1ed1i \u0111a kh\u00f4ng qu\u00e1 80 mg\/ng\u00e0y. Ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n tu\u00e2n th\u1ee7 ch\u1ebf \u0111\u1ed9 \u0103n \u00edt cholesterol tr\u01b0\u1edbc v\u00e0 trong qu\u00e1 tr\u00ecnh d\u00f9ng thu\u1ed1c.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p><strong>Vi\u00ean n\u00e9n Zoamco-A<\/strong> d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng, c\u00f3 th\u1ec3 u\u1ed1ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng b\u1eefa \u0103n, v\u00e0o b\u1ea5t k\u1ef3 th\u1eddi \u0111i\u1ec3m n\u00e0o trong ng\u00e0y. N\u00ean u\u1ed1ng v\u00e0o m\u1ed9t gi\u1edd c\u1ed1 \u0111\u1ecbnh \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Zoamco-A trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi m\u1eabn c\u1ea3m v\u1edbi Amlodipin, Atorvastatin ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>B\u1ec7nh nh\u00e2n c\u00f3 b\u1ec7nh gan ti\u1ebfn tri\u1ec3n ho\u1eb7c men gan t\u0103ng k\u00e9o d\u00e0i kh\u00f4ng r\u00f5 nguy\u00ean nh\u00e2n.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Zoamco-A<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Thu\u1ed1c c\u1ea7n \u0111\u01b0\u1ee3c d\u00f9ng th\u1eadn tr\u1ecdng \u1edf b\u1ec7nh nh\u00e2n suy gi\u1ea3m ch\u1ee9c n\u0103ng gan, ng\u01b0\u1eddi b\u1ecb h\u1eb9p van \u0111\u1ed9ng m\u1ea1ch ch\u1ee7 ho\u1eb7c m\u1edbi tr\u1ea3i qua nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p.<\/p>\n<p>Tr\u01b0\u1edbc khi \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Zoamco-A, c\u1ea7n ki\u1ec3m so\u00e1t t\u0103ng cholesterol m\u00e1u b\u1eb1ng thay \u0111\u1ed5i ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng, luy\u1ec7n t\u1eadp th\u1ec3 l\u1ef1c v\u00e0 gi\u1ea3m c\u00e2n n\u1ebfu th\u1eeba c\u00e2n\/b\u00e9o ph\u00ec.<\/p>\n<p>N\u00ean ki\u1ec3m tra men gan tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u d\u00f9ng statin v\u00e0 l\u00e0m l\u1ea1i x\u00e9t nghi\u1ec7m khi c\u00f3 ch\u1ec9 \u0111\u1ecbnh.<\/p>\n<p>C\u1ea7n theo d\u00f5i creatin kinase (CK) trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p c\u00f3 nguy c\u01a1 cao nh\u01b0: b\u1ec7nh nh\u00e2n suy th\u1eadn, suy gi\u00e1p, c\u00f3 ti\u1ec1n s\u1eed c\u00e1 nh\u00e2n ho\u1eb7c gia \u0111\u00ecnh m\u1eafc b\u1ec7nh c\u01a1 di truy\u1ec1n, t\u1eebng g\u1eb7p t\u00e1c d\u1ee5ng ph\u1ee5 v\u1ec1 c\u01a1 khi d\u00f9ng statin ho\u1eb7c fibrat, ti\u1ec1n s\u1eed b\u1ec7nh gan, u\u1ed1ng nhi\u1ec1u r\u01b0\u1ee3u, ng\u01b0\u1eddi cao tu\u1ed5i tr\u00ean 70 c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1 ti\u00eau c\u01a1 v\u00e2n, ho\u1eb7c c\u00f3 kh\u1ea3 n\u0103ng x\u1ea3y ra t\u01b0\u01a1ng t\u00e1c thu\u1ed1c.<\/p>\n<p>N\u1ebfu k\u1ebft qu\u1ea3 CK cao g\u1ea5p 5 l\u1ea7n gi\u1edbi h\u1ea1n b\u00ecnh th\u01b0\u1eddng, kh\u00f4ng n\u00ean kh\u1edfi \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u1edbi statin.<\/p>\n<p>Trong qu\u00e1 tr\u00ecnh d\u00f9ng thu\u1ed1c, n\u1ebfu ng\u01b0\u1eddi b\u1ec7nh xu\u1ea5t hi\u1ec7n tri\u1ec7u ch\u1ee9ng \u0111au c\u01a1, y\u1ebfu c\u01a1 ho\u1eb7c c\u1ee9ng c\u01a1, c\u1ea7n th\u00f4ng b\u00e1o ngay cho b\u00e1c s\u0129 \u0111\u1ec3 \u0111\u01b0\u1ee3c x\u00e9t nghi\u1ec7m CK v\u00e0 c\u00f3 h\u01b0\u1edbng x\u1eed tr\u00ed k\u1ecbp th\u1eddi.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Zoamco-A nh\u00ecn chung dung n\u1ea1p t\u1ed1t, nh\u01b0ng c\u00f3 th\u1ec3 g\u00e2y m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n, th\u01b0\u1eddng nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh nh\u01b0: m\u1ec7t m\u1ecfi, bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, ph\u00f9 n\u1ec1, suy nh\u01b0\u1ee3c, \u0111au b\u1ee5ng, bu\u1ed3n n\u00f4n, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a, m\u1ea5t ng\u1ee7, \u0111au c\u01a1, ph\u00e1t ban.<br \/>\nM\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p c\u00f3 th\u1ec3 g\u1eb7p t\u0103ng \u0111\u01b0\u1eddng huy\u1ebft, t\u0103ng HbA1c. Hi\u1ebfm g\u1eb7p h\u01a1n l\u00e0 suy gi\u1ea3m nh\u1eadn th\u1ee9c (l\u00fa l\u1eabn, \u0111\u00e3ng tr\u00ed).<br \/>\nNg\u01b0\u1eddi b\u1ec7nh c\u1ea7n b\u00e1o cho b\u00e1c s\u0129 ho\u1eb7c d\u01b0\u1ee3c s\u0129 n\u1ebfu xu\u1ea5t hi\u1ec7n b\u1ea5t k\u1ef3 ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i n\u00e0o trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p><em><strong>Amlodipin<\/strong><\/em><\/p>\n<p>Khi ph\u1ed1i h\u1ee3p v\u1edbi thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid (NSAID), \u0111\u1eb7c bi\u1ec7t l\u00e0 indomethacin, c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 h\u1ea1 huy\u1ebft \u00e1p do \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p prostaglandin \u1edf th\u1eadn ho\u1eb7c g\u00e2y gi\u1eef mu\u1ed1i n\u01b0\u1edbc.<\/p>\n<p>Estrogen c\u00f3 th\u1ec3 g\u00e2y gi\u1eef n\u01b0\u1edbc, l\u00e0m t\u0103ng huy\u1ebft \u00e1p.<\/p>\n<p>C\u00e1c thu\u1ed1c k\u00edch th\u00edch h\u1ec7 th\u1ea7n kinh giao c\u1ea3m c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng h\u1ea1 \u00e1p c\u1ee7a Amlodipin.<\/p>\n<p><em><strong>Atorvastatin<\/strong><\/em><\/p>\n<p>Nguy c\u01a1 t\u1ed5n th\u01b0\u01a1ng c\u01a1 t\u0103ng l\u00ean khi d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi gemfibrozil, c\u00e1c fibrat kh\u00e1c, niacin li\u1ec1u cao (&gt;1 g\/ng\u00e0y) ho\u1eb7c colchicin.<\/p>\n<p>N\u1ed3ng \u0111\u1ed9 atorvastatin gi\u1ea3m khi d\u00f9ng chung v\u1edbi thu\u1ed1c kh\u00e1ng acid ch\u1ee9a nh\u00f4m, magnesi ho\u1eb7c colestipol.<\/p>\n<p>N\u1ed3ng \u0111\u1ed9 atorvastatin trong m\u00e1u t\u0103ng khi ph\u1ed1i h\u1ee3p v\u1edbi erythromycin, clarithromycin, cyclosporin, ho\u1eb7c thu\u1ed1c kh\u00e1ng n\u1ea5m azol.<\/p>\n<p>Khi d\u00f9ng chung v\u1edbi thu\u1ed1c \u1ee9c ch\u1ebf protease \u0111i\u1ec1u tr\u1ecb HIV\/HCV, nguy c\u01a1 ti\u00eau c\u01a1 v\u00e2n v\u00e0 suy th\u1eadn c\u00f3 th\u1ec3 gia t\u0103ng:<\/p>\n<p>Tr\u00e1nh ph\u1ed1i h\u1ee3p v\u1edbi telaprevir, tipranavir + ritonavir.<\/p>\n<p>V\u1edbi lopinavir + ritonavir: c\u1ea7n th\u1eadn tr\u1ecdng v\u00e0 ch\u1ec9 d\u00f9ng li\u1ec1u atorvastatin th\u1ea5p.<\/p>\n<p>V\u1edbi fosamprenavir, fosamprenavir + ritonavir, saquinavir + ritonavir, darunavir + ritonavir: kh\u00f4ng v\u01b0\u1ee3t qu\u00e1 20 mg atorvastatin\/ng\u00e0y.<\/p>\n<p>V\u1edbi nelfinavir: kh\u00f4ng d\u00f9ng qu\u00e1 40 mg atorvastatin\/ng\u00e0y.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>C\u00e1c nghi\u00ean c\u1ee9u \u1edf \u0111\u1ed9ng v\u1eadt v\u00e0 ng\u01b0\u1eddi \u0111\u1ec1u cho th\u1ea5y nguy c\u01a1 g\u00e2y h\u1ea1i cho thai nhi khi d\u00f9ng statin. V\u00ec l\u1ee3i \u00edch kh\u00f4ng v\u01b0\u1ee3t tr\u1ed9i so v\u1edbi nguy c\u01a1, Zoamco-A ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh cho ph\u1ee5 n\u1eef \u0111ang mang thai ho\u1eb7c c\u00f3 kh\u1ea3 n\u0103ng mang thai. Thu\u1ed1c c\u0169ng kh\u00f4ng n\u00ean d\u00f9ng trong th\u1eddi k\u1ef3 cho con b\u00fa.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Zoamco-A kh\u00f4ng g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe hay v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Amlodipin: Ng\u1ed9 \u0111\u1ed9c hi\u1ebfm g\u1eb7p. Khi qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 g\u00e2y t\u1ee5t huy\u1ebft \u00e1p, nh\u1ecbp ch\u1eadm ho\u1eb7c block tim. X\u1eed tr\u00ed b\u1eb1ng theo d\u00f5i tim m\u1ea1ch li\u00ean t\u1ee5c, r\u1eeda d\u1ea1 d\u00e0y, d\u00f9ng than ho\u1ea1t, b\u00f9 d\u1ecbch \u0111i\u1ec7n gi\u1ea3i, ti\u00eam t\u0129nh m\u1ea1ch atropin n\u1ebfu nh\u1ecbp ch\u1eadm, c\u00f3 th\u1ec3 d\u00f9ng calci gluconat truy\u1ec1n t\u0129nh m\u1ea1ch ho\u1eb7c thu\u1ed1c v\u1eadn m\u1ea1ch nh\u01b0 isoprenalin, adrenalin, dopamin. Tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng c\u00f3 th\u1ec3 \u0111\u1eb7t m\u00e1y t\u1ea1o nh\u1ecbp.<\/p>\n<p>Atorvastatin: Kh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u. X\u1eed tr\u00ed ch\u1ee7 y\u1ebfu l\u00e0 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 h\u1ed7 tr\u1ee3. Do thu\u1ed1c g\u1eafn m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng, th\u1ea9m t\u00e1ch m\u00e1u kh\u00f4ng l\u00e0m t\u0103ng \u0111\u00e0o th\u1ea3i atorvastatin.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Zoamco-A \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Zoamco-A trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Zoamco-A khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Zoamco-A \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/To-huong-dan-su-dung-Zoamco-A-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 9 th\u00e1ng 9 n\u0103m 2025<\/li>\n<li>Messerli FH, Bakris GL, Ferrera D, Houston MC, Petrella RJ, Flack JM, Sun W, Lee E, Neutel JM; AVALON Investigators (2006). Efficacy and safety of coadministered amlodipine and atorvastatin in patients with hypertension and dyslipidemia: results of the AVALON trial. J Clin Hypertens (Greenwich). Truy c\u1eadp ng\u00e0y 9 th\u00e1ng 9 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8109721\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8109721\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Zoamco-A c\u00f3 t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p, v\u1eeba gi\u00fap gi\u1ea3m cholesterol m\u00e1u \u0111\u01b0\u1ee3c d\u00f9ng cho nh\u1eefng b\u1ec7nh nh\u00e2n c\u1ea7n \u0111i\u1ec1u tr\u1ecb k\u1ebft h\u1ee3p c\u1ea3 t\u0103ng huy\u1ebft \u00e1p, \u0111au th\u1eaft ng\u1ef1c v\u00e0 r\u1ed1i lo\u1ea1n lipid m\u00e1u<\/p>\n","protected":false},"author":1,"featured_media":137841,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-137839","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/137839","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=137839"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/137841"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=137839"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=137839"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=137839"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}