{"id":137719,"date":"2025-09-09T12:28:49","date_gmt":"2025-09-09T05:28:49","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=137719"},"modified":"2025-09-09T12:30:01","modified_gmt":"2025-09-09T05:30:01","slug":"spinolac-50mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/spinolac-50mg\/","title":{"rendered":"Spinolac 50mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <a href=\"https:\/\/vnras.com\/drug\/?post_type=product&amp;p=137719&amp;preview=true\"><strong>Spinolac 50mg<\/strong><\/a><strong> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Ha san &#8211; Dermapharm, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-12651-10.<\/strong><\/p>\n<h2>Spinolac 50mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Spinolac 50mg <\/strong>l\u00e0 m\u1ed9t thu\u1ed1c k\u00ea \u0111\u01a1n, thu\u1ed9c nh\u00f3m thu\u1ed1c l\u1ee3i ti\u1ec3u gi\u1eef kali, m\u1ed7i vi\u00ean n\u00e9n ch\u1ee9a d\u01b0\u1ee3c ch\u1ea5t <strong>Spironolactone <\/strong>50 mg.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-12651-10<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 2 V\u1ec9 x 10 Vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_137723\" aria-describedby=\"caption-attachment-137723\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-137723\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Spinolac-50mg.jpg\" alt=\"Spinolac 50mg \u0111i\u1ec1u tr\u1ecb ph\u00f9 tim do sung huy\u1ebft\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Spinolac-50mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Spinolac-50mg-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Spinolac-50mg-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Spinolac-50mg-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Spinolac-50mg-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-137723\" class=\"wp-caption-text\">Spinolac 50mg \u0111i\u1ec1u tr\u1ecb ph\u00f9 tim do sung huy\u1ebft<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Spinolac 50mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Spironolactone ph\u00e1t huy t\u00e1c d\u1ee5ng th\u00f4ng qua vi\u1ec7c \u1ee9c ch\u1ebf c\u1ea1nh tranh v\u1edbi aldosterone t\u1ea1i c\u00e1c th\u1ee5 th\u1ec3 mineralocorticoid. V\u1ecb tr\u00ed t\u00e1c \u0111\u1ed9ng ch\u1ee7 y\u1ebfu l\u00e0 \u1edf \u1ed1ng l\u01b0\u1ee3n xa v\u00e0 \u1ed1ng g\u00f3p c\u1ee7a th\u1eadn. Aldosterone l\u00e0 m\u1ed9t hormone t\u1ef1 nhi\u00ean g\u00e2y gi\u1eef mu\u1ed1i (natri) v\u00e0 n\u01b0\u1edbc, \u0111\u1ed3ng th\u1eddi l\u00e0m t\u0103ng b\u00e0i ti\u1ebft kali. B\u1eb1ng c\u00e1ch kh\u00f3a c\u00e1c th\u1ee5 th\u1ec3 n\u00e0y, Spironolactone \u0111\u1ea3o ng\u01b0\u1ee3c t\u00e1c d\u1ee5ng c\u1ee7a aldosterone, d\u1eabn \u0111\u1ebfn:<\/p>\n<ul>\n<li>T\u0103ng b\u00e0i ti\u1ebft natri v\u00e0 n\u01b0\u1edbc: G\u00e2y ra t\u00e1c d\u1ee5ng l\u1ee3i ti\u1ec3u, gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n, t\u1eeb \u0111\u00f3 gi\u00fap gi\u1ea3m ph\u00f9 v\u00e0 h\u1ea1 huy\u1ebft \u00e1p.<\/li>\n<li>Gi\u1eef l\u1ea1i kali v\u00e0 ion hydro: \u0110\u00e2y l\u00e0 \u0111\u1eb7c t\u00ednh &#8220;gi\u1eef kali&#8221; \u0111\u1eb7c tr\u01b0ng c\u1ee7a thu\u1ed1c, gi\u00fap ng\u0103n ng\u1eeba t\u00ecnh tr\u1ea1ng h\u1ea1 kali m\u00e1u th\u01b0\u1eddng g\u1eb7p khi d\u00f9ng c\u00e1c nh\u00f3m thu\u1ed1c l\u1ee3i ti\u1ec3u kh\u00e1c (nh\u01b0 thiazid ho\u1eb7c l\u1ee3i ti\u1ec3u quai).<\/li>\n<\/ul>\n<p>Ngo\u00e0i t\u00e1c d\u1ee5ng t\u1ea1i th\u1eadn, vi\u1ec7c kh\u00e1ng aldosterone c\u00f2n mang l\u1ea1i l\u1ee3i \u00edch tr\u00ean h\u1ec7 tim m\u1ea1ch, bao g\u1ed3m vi\u1ec7c gi\u1ea3m ph\u00ec \u0111\u1ea1i v\u00e0 x\u01a1 h\u00f3a c\u01a1 tim, nh\u1eefng qu\u00e1 tr\u00ecnh b\u1ec7nh l\u00fd then ch\u1ed1t trong suy tim.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Spironolactone \u0111\u01b0\u1ee3c h\u1ea5p thu t\u1ed1t qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, v\u00e0 vi\u1ec7c d\u00f9ng thu\u1ed1c c\u00f9ng v\u1edbi th\u1ee9c \u0103n c\u00f3 th\u1ec3 l\u00e0m t\u0103ng sinh kh\u1ea3 d\u1ee5ng l\u00ean g\u1ea7n 100%. Thu\u1ed1c li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (kho\u1ea3ng 90%) v\u00e0 \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a nhanh ch\u00f3ng th\u00e0nh c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh, bao g\u1ed3m canrenone v\u00e0 7-alpha thiomethyl spironolactone, g\u00f3p ph\u1ea7n k\u00e9o d\u00e0i t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c. C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a n\u00e0y \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u.<\/p>\n<h2>Thu\u1ed1c Spinolac 50mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Suy tim sung huy\u1ebft: \u0110\u1eb7c bi\u1ec7t trong \u0111i\u1ec1u tr\u1ecb suy tim n\u1eb7ng (\u0111\u1ed9 III-IV theo ph\u00e2n lo\u1ea1i NYHA) \u0111\u1ec3 c\u1ea3i thi\u1ec7n tri\u1ec7u ch\u1ee9ng, gi\u1ea3m t\u1ef7 l\u1ec7 nh\u1eadp vi\u1ec7n v\u00e0 c\u1ea3i thi\u1ec7n t\u1ef7 l\u1ec7 s\u1ed1ng c\u00f2n. Th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng RALES (Randomized Aldactone Evaluation Study) kinh \u0111i\u1ec3n \u0111\u00e3 ch\u1ee9ng minh r\u1eb1ng vi\u1ec7c b\u1ed5 sung Spironolactone v\u00e0o ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb chu\u1ea9n \u1edf b\u1ec7nh nh\u00e2n suy tim n\u1eb7ng v\u1edbi ph\u00e2n su\u1ea5t t\u1ed1ng m\u00e1u gi\u1ea3m (HFrEF) gi\u00fap gi\u1ea3m 30% nguy c\u01a1 t\u1eed vong do m\u1ecdi nguy\u00ean nh\u00e2n.<\/p>\n<p>Ph\u00f9 do c\u00e1c nguy\u00ean nh\u00e2n kh\u00e1c: Bao g\u1ed3m x\u01a1 gan c\u1ed5 tr\u01b0\u1edbng v\u00e0 h\u1ed9i ch\u1ee9ng th\u1eadn h\u01b0, khi c\u00e1c li\u1ec7u ph\u00e1p kh\u00e1c kh\u00f4ng \u0111\u1ee7 hi\u1ec7u qu\u1ea3.<\/p>\n<p>T\u0103ng huy\u1ebft \u00e1p: Th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 m\u1ed9t li\u1ec7u ph\u00e1p b\u1ed5 tr\u1ee3, \u0111\u1eb7c bi\u1ec7t hi\u1ec7u qu\u1ea3 trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p t\u0103ng huy\u1ebft \u00e1p kh\u00e1ng tr\u1ecb.<\/p>\n<p>Ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb c\u01b0\u1eddng aldosteron ti\u00ean ph\u00e1t (H\u1ed9i ch\u1ee9ng Conn): Spironolactone \u0111\u01b0\u1ee3c d\u00f9ng c\u1ea3 trong nghi\u1ec7m ph\u00e1p ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb duy tr\u00ec d\u00e0i h\u1ea1n cho b\u1ec7nh nh\u00e2n kh\u00f4ng ph\u00f9 h\u1ee3p ph\u1eabu thu\u1eadt.<\/p>\n<p>B\u1ec7nh c\u1ed5 tr\u01b0\u1edbng \u00e1c t\u00ednh.<\/p>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Spinolac 50mg<\/h2>\n<p>Li\u1ec1u l\u01b0\u1ee3ng ph\u1ea3i \u0111\u01b0\u1ee3c c\u00e1 nh\u00e2n h\u00f3a v\u00e0 \u0111i\u1ec1u ch\u1ec9nh b\u1edfi b\u00e1c s\u0129 d\u1ef1a tr\u00ean t\u00ecnh tr\u1ea1ng b\u1ec7nh v\u00e0 \u0111\u00e1p \u1ee9ng c\u1ee7a b\u1ec7nh nh\u00e2n.<\/p>\n<ul>\n<li>\u0110\u1ec3 \u0111i\u1ec1u tr\u1ecb t\u00ecnh tr\u1ea1ng ph\u00f9 do suy tim sung huy\u1ebft, li\u1ec1u kh\u1edfi \u0111\u1ea7u l\u00e0 100 mg\/ng\u00e0y, v\u1edbi kho\u1ea3ng li\u1ec1u d\u00f9ng c\u00f3 th\u1ec3 dao \u0111\u1ed9ng t\u1eeb 25 \u0111\u1ebfn 200 mg\/ng\u00e0y.<\/li>\n<li>Suy tim n\u1eb7ng (NYHA III-IV): Li\u1ec1u kh\u1edfi \u0111\u1ea7u khuy\u1ebfn c\u00e1o l\u00e0 25 mg\/l\u1ea7n\/ng\u00e0y.<\/li>\n<li>X\u01a1 gan c\u1ed5 tr\u01b0\u1edbng: 100 &#8211; 400 mg\/ng\u00e0y t\u00f9y theo t\u1ef7 l\u1ec7 Na+\/K+ trong n\u01b0\u1edbc ti\u1ec3u.<\/li>\n<li>H\u1ed9i ch\u1ee9ng th\u1eadn h\u01b0: 100 &#8211; 200 mg\/ng\u00e0y.<\/li>\n<li>Tr\u1ebb em: Li\u1ec1u kh\u1edfi \u0111\u1ea7u 1 &#8211; 3 mg\/kg\/ng\u00e0y, chia th\u00e0nh nhi\u1ec1u li\u1ec1u.<\/li>\n<\/ul>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Spinolac 50mg<\/h2>\n<p>Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng v\u00e0 n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng chung v\u1edbi th\u1ee9c \u0103n \u0111\u1ec3 t\u0103ng kh\u1ea3 n\u0103ng h\u1ea5p thu.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Spinolac 50mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Qu\u00e1 m\u1eabn v\u1edbi Spironolactone ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>Suy th\u1eadn c\u1ea5p, suy th\u1eadn n\u1eb7ng (eGFR &lt; 30 ml\/ph\u00fat\/1,73 m\u00b2), ho\u1eb7c v\u00f4 ni\u1ec7u.<\/p>\n<p>T\u0103ng kali m\u00e1u (n\u1ed3ng \u0111\u1ed9 kali huy\u1ebft thanh &gt; 5 mmol\/l).<\/p>\n<p>B\u1ec7nh Addison.<\/p>\n<p>S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c l\u1ee3i ti\u1ec3u gi\u1eef kali kh\u00e1c ho\u1eb7c c\u00e1c ch\u1ebf ph\u1ea9m b\u1ed5 sung kali.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Spinolac 50mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>C\u1ea3nh b\u00e1o quan tr\u1ecdng nh\u1ea5t v\u00e0 \u0111\u01b0\u1ee3c quan t\u00e2m h\u00e0ng \u0111\u1ea7u khi s\u1eed d\u1ee5ng Spironolactone l\u00e0 nguy c\u01a1 t\u0103ng kali m\u00e1u (Hyperkalemia). \u0110\u00e2y l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c bi\u1ebfn ch\u1ee9ng tim m\u1ea1ch nghi\u00eam tr\u1ecdng, th\u1eadm ch\u00ed t\u1eed vong. Nguy c\u01a1 n\u00e0y t\u0103ng cao \u0111\u00e1ng k\u1ec3 \u1edf c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng:<\/p>\n<ul>\n<li>B\u1ec7nh nh\u00e2n suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn.<\/li>\n<li>B\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng.<\/li>\n<li>Ng\u01b0\u1eddi cao tu\u1ed5i.<\/li>\n<li>B\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng \u0111\u1ed3ng th\u1eddi c\u00e1c thu\u1ed1c kh\u00e1c c\u0169ng l\u00e0m t\u0103ng kali m\u00e1u nh\u01b0: thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n (ACEi), thu\u1ed1c ch\u1eb9n th\u1ee5 th\u1ec3 angiotensin II (ARB), thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00f4ng steroid (NSAID), thu\u1ed1c b\u1ed5 sung kali.<\/li>\n<\/ul>\n<p>Do \u0111\u00f3, vi\u1ec7c theo d\u00f5i ch\u1eb7t ch\u1ebd n\u1ed3ng \u0111\u1ed9 kali v\u00e0 creatinin (ch\u1ee9c n\u0103ng th\u1eadn) trong huy\u1ebft thanh l\u00e0 b\u1eaft bu\u1ed9c. B\u1ec7nh nh\u00e2n n\u00ean ng\u01b0ng ho\u1eb7c t\u1ea1m ng\u01b0ng thu\u1ed1c n\u1ebfu kali huy\u1ebft thanh &gt; 5 mEq\/L.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>R\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i: T\u0103ng kali m\u00e1u l\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p v\u00e0 nguy hi\u1ec3m nh\u1ea5t. H\u1ea1 natri m\u00e1u c\u0169ng c\u00f3 th\u1ec3 x\u1ea3y ra.<\/p>\n<p>T\u00e1c d\u1ee5ng ph\u1ee5 li\u00ean quan \u0111\u1ebfn n\u1ed9i ti\u1ebft: Do c\u1ea5u tr\u00fac steroid c\u1ee7a Spironolactone v\u00e0 t\u00e1c \u0111\u1ed9ng kh\u00f4ng ch\u1ecdn l\u1ecdc l\u00ean c\u00e1c th\u1ee5 th\u1ec3 androgen v\u00e0 progesterone, thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ra:<\/p>\n<ul>\n<li>\u1ede nam gi\u1edbi: Ch\u1ee9ng v\u00fa to (gynecomastia), \u0111au v\u00fa, gi\u1ea3m ham mu\u1ed1n t\u00ecnh d\u1ee5c, r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng d\u01b0\u01a1ng. \u0110\u00e2y l\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn, ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec1u l\u01b0\u1ee3ng v\u00e0 th\u01b0\u1eddng h\u1ed3i ph\u1ee5c sau khi ng\u01b0ng thu\u1ed1c.<\/li>\n<li>\u1ede n\u1eef gi\u1edbi: R\u1ed1i lo\u1ea1n kinh nguy\u1ec7t, c\u0103ng v\u00fa, ch\u1ea3y m\u00e1u sau m\u00e3n kinh.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>C\u1ea7n h\u1ebft s\u1ee9c th\u1eadn tr\u1ecdng khi ph\u1ed1i h\u1ee3p Spinolac 50mg v\u1edbi c\u00e1c thu\u1ed1c sau \u0111\u00e2y do nguy c\u01a1 t\u0103ng kali m\u00e1u tr\u1ea7m tr\u1ecdng:<\/p>\n<ul>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n (ACEi) v\u00e0 Thu\u1ed1c ch\u1eb9n th\u1ee5 th\u1ec3 Angiotensin II (ARB).<\/li>\n<li>C\u00e1c ch\u1ebf ph\u1ea9m b\u1ed5 sung kali ho\u1eb7c c\u00e1c ch\u1ea5t thay th\u1ebf mu\u1ed1i ch\u1ee9a kali.<\/li>\n<li>Thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00f4ng steroid (NSAIDs) nh\u01b0 Ibuprofen, Diclofenac.<\/li>\n<li>C\u00e1c thu\u1ed1c l\u1ee3i ti\u1ec3u gi\u1eef kali kh\u00e1c.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai: Spironolactone v\u00e0 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 th\u1ec3 \u0111i qua h\u00e0ng r\u00e0o nhau thai, ch\u1ec9 n\u00ean s\u1eed d\u1ee5ng khi l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1 ti\u1ec1m t\u00e0ng cho thai nhi.<\/p>\n<p>Ph\u1ee5 n\u1eef cho con b\u00fa: Ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a thu\u1ed1c \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong s\u1eefa m\u1eb9. Kh\u00f4ng n\u00ean d\u00f9ng thu\u1ed1c trong th\u1eddi k\u1ef3 cho con b\u00fa, n\u1ebfu b\u1eaft bu\u1ed9c ph\u1ea3i s\u1eed d\u1ee5ng th\u00ec n\u00ean ng\u01b0ng cho con b\u00fa.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ng\u1ee7 g\u00e0 v\u00e0 ch\u00f3ng m\u1eb7t \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n, c\u1ea7n th\u1eadn tr\u1ecdng khi l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 bao g\u1ed3m bu\u1ed3n ng\u1ee7, l\u00fa l\u1eabn, bu\u1ed3n n\u00f4n, n\u00f4n, v\u00e0 r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i. Kh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u; x\u1eed tr\u00ed ch\u1ee7 y\u1ebfu l\u00e0 \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3, b\u00f9 n\u01b0\u1edbc, v\u00e0 \u0111i\u1ec1u ch\u1ec9nh r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i, \u0111\u1eb7c bi\u1ec7t l\u00e0 t\u00ecnh tr\u1ea1ng t\u0103ng kali m\u00e1u.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n thu\u1ed1c Spinolac 50mg \u1edf n\u01a1i kh\u00f4, d\u01b0\u1edbi 30\u00b0C v\u00e0 tr\u00e1nh \u00e1nh s\u00e1ng.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Spinolac 50mg<\/h2>\n<p>Tr\u00ean th\u1ecb tr\u01b0\u1eddng c\u00f3 nhi\u1ec1u s\u1ea3n ph\u1ea9m ch\u1ee9a ho\u1ea1t ch\u1ea5t Spironolactone 50mg, m\u1ed9t trong s\u1ed1 \u0111\u00f3 l\u00e0 thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/spironolacton-tab-dwp-50mg\/\">Spironolacton Tab DWP 50mg<\/a>. S\u1ea3n ph\u1ea9m n\u00e0y c\u0169ng l\u00e0 m\u1ed9t thu\u1ed1c l\u1ee3i ti\u1ec3u gi\u1eef kali, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n, suy tim sung huy\u1ebft v\u00e0 c\u00e1c t\u00ecnh tr\u1ea1ng ph\u00f9 n\u1ec1. Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng t\u01b0\u01a1ng t\u1ef1 nh\u01b0 Spinolac 50mg, v\u00e0 c\u0169ng c\u1ea7n \u0111\u01b0\u1ee3c u\u1ed1ng sau b\u1eefa \u0103n \u0111\u1ec3 t\u0103ng h\u1ea5p thu.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Allan Struthers, Henry Krum,. A comparison of the aldosterone-blocking agents eplerenone and spironolactone, truy c\u1eadp ng\u00e0y 09 th\u00e1ng 09 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18404673\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/18404673\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>S\u1ea3n ph\u1ea9m thu\u1ed1c Spinolac 50mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Ha san &#8211; Dermapharm, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-12651-10, \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00fd tim m\u1ea1ch, th\u1eadn v\u00e0 n\u1ed9i ti\u1ebft.<\/p>\n","protected":false},"author":1,"featured_media":137720,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-137719","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/137719","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=137719"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/137720"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=137719"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=137719"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=137719"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}