{"id":137242,"date":"2025-09-06T20:40:51","date_gmt":"2025-09-06T13:40:51","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=137242"},"modified":"2025-09-06T21:11:04","modified_gmt":"2025-09-06T14:11:04","slug":"bihasal-5mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/bihasal-5mg\/","title":{"rendered":"Bihasal 5mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <a href=\"https:\/\/vnras.com\/drug\/\">d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/a> xin gi\u1edbi thi\u1ec7u \u0111\u1ebfn b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/bihasal-5mg\/\">Bihasal 5mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Hasan-Dermapharm c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-34895-20.<\/strong><\/p>\n<h2>Bihasal 5 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<p>Bihasal 5mg ch\u1ee9a th\u00e0nh ph\u1ea7n l\u00e0 Bisoprolol fumarat, m\u1ed9t ho\u1ea1t ch\u1ea5t c\u00f3 t\u00e1c d\u1ee5ng tr\u00ean tim m\u1ea1ch nh\u1edd c\u01a1 ch\u1ebf ch\u1eb9n th\u1ee5 th\u1ec3\u00a0 \u03b21- adrenergic. Thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m h\u1ea1 huy\u1ebft \u00e1p tr\u00ean ng\u01b0\u1eddi m\u1eafc huy\u1ebft \u00e1p cao, \u1ed5n \u0111\u1ecbnh c\u01a1n \u0111au th\u1eaft ng\u1ef1c v\u00e0 t\u00ecnh tr\u1ea1ng suy tim m\u1ea1n t\u00ednh.<\/p>\n<figure id=\"attachment_137254\" aria-describedby=\"caption-attachment-137254\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-137254\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/BIHASAL-5.jpg\" alt=\"Thu\u1ed1c Bihasal 5 \u0111i\u1ec1u tr\u1ecb cao huy\u1ebft \u00e1p, \u0111au th\u1eaft ng\u1ef1c v\u00e0 suy tim m\u1ea1n t\u00ednh.\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/BIHASAL-5.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/BIHASAL-5-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/BIHASAL-5-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/BIHASAL-5-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/BIHASAL-5-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-137254\" class=\"wp-caption-text\">Thu\u1ed1c Bihasal 5 \u0111i\u1ec1u tr\u1ecb cao huy\u1ebft \u00e1p, \u0111au th\u1eaft ng\u1ef1c v\u00e0 suy tim m\u1ea1n t\u00ednh.<\/figcaption><\/figure>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean Bihasal 5 ch\u1ee9a:<\/p>\n<p>D\u01b0\u1ee3c ch\u1ea5t: Bisoprolol fumarat \u2026\u2026\u2026\u2026\u2026.\u2026\u20265mg<\/p>\n<p>T\u00e1 d\u01b0\u1ee3c: lactose, tinh b\u1ed9t ng\u00f4, Avicel M101,Aerosil, Manegsi stearat, Primellose, HPMC 606, HPMC 615, PEG 6000, Titan dioxyd, Oxyd s\u1eaft v\u00e0ng..<\/p>\n<h3>D\u1ea1ng b\u00e0o ch\u1ebf<\/h3>\n<p>Vi\u00ean n\u00e9n tr\u00f2n d\u1eb9t, m\u00e0u tr\u1eafng ng\u00e0 ho\u1eb7c h\u01a1i v\u00e0ng, c\u00f3 bao phim.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<ul>\n<li>S\u0110K: VD-34895-20.<\/li>\n<li>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 5 v\u1ec9 x 10 vi\u00ean.<\/li>\n<li>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam.<\/li>\n<li>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng k\u1ec3 t\u1eeb ng\u00e0y s\u1ea3n xu\u1ea5t.<\/li>\n<\/ul>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a Bihasal 5<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Bisoprolol l\u00e0 m\u1ed9t thu\u1ed1c ch\u1eb9n th\u1ee5 th\u1ec3 adrenergic ch\u1ecdn l\u1ecdc \u03b21 (ch\u1ecdn l\u1ecdc tr\u00ean tim) v\u00e0 c\u00f3 \u00e1i l\u1ef1c th\u1ea5p v\u1edbi th\u1ee5 th\u1ec3\u00a0 \u03b22 v\u1edbi li\u1ec1u th\u1ea5p. Nh\u01b0ng \u1edf li\u1ec1u cao, t\u00ednh ch\u1ecdn l\u1ecdc c\u1ee7a Bisoprolol gi\u1ea3m xu\u1ed1ng, do \u0111\u00f3 c\u00f3 th\u1ec3 \u1ee9c ch\u1ebf c\u1ea1nh tranh c\u1ea3 2 th\u1ee5 th\u1ec3\u00a0 \u03b21 v\u00e0\u00a0 \u03b22.<\/p>\n<p>Bisoprolol l\u00e0m gi\u1ea3m nh\u1ecbp tim, gi\u1ea3m cung l\u01b0\u1ee3ng tim v\u00e0 \u1ee9c ch\u1ebf gi\u1ea3i ph\u00f3ng renin t\u1eeb th\u1eadn nh\u1edd \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc c\u00e1c th\u1ee5 th\u1ec3 adrenergic, nh\u1edd \u0111\u00f3 \u0111i\u1ec1u ch\u1ec9nh qu\u00e1 tr\u00ecnh t\u00e1i h\u1ea5p thu Natri v\u00e0 Kali, \u0111\u1ed3ng th\u1eddi g\u00e2y gi\u00e3n m\u1ea1ch. K\u1ebft qu\u1ea3 l\u00e0 l\u00e0m gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n, gi\u1ea3m s\u1ee9c c\u1ea3n c\u1ee7a c\u00e1c m\u1ea1ch ngo\u1ea1i vi d\u1eabn \u0111\u1ebfn h\u1ea1 huy\u1ebft \u00e1p.<\/p>\n<p>D\u00f9ng Bisoprolol l\u00e2u d\u00e0i ho\u1eb7c ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n, l\u1ee3i ti\u1ec3u hay glycosid tr\u1ee3 tim c\u0169ng c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng suy tim v\u00e0 c\u1ea3i thi\u1ec7n t\u00ecnh tr\u1ea1ng c\u1ee7a ng\u01b0\u1eddi m\u1eafc suy tim m\u1ea1n, l\u00e0m gi\u1ea3m t\u00ecnh tr\u1ea1ng suy tim ti\u1ebfn tri\u1ec3n. T\u00e1c d\u1ee5ng n\u00e0y ch\u1ee7 y\u1ebfu l\u00e0 do Bisoprolol \u1ee9c ch\u1ebf c\u00e1c t\u00e1c \u0111\u1ed9ng c\u1ee7a h\u1ec7 th\u1ea7n kinh giao c\u1ea3m.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<h4>H\u1ea5p thu<\/h4>\n<ul>\n<li>Sau khi u\u1ed1ng, th\u00f4ng qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, Bisoprolol \u0111\u01b0\u1ee3c h\u1ea5p thu ho\u00e0n to\u00e0n.<\/li>\n<li>Thu\u1ed1c v\u00e0o c\u01a1 th\u1ec3 \u0111\u1ea1t sinh kh\u1ea3 d\u1ee5ng cao, kho\u1ea3ng 90%.<\/li>\n<li>Th\u1ee9c \u0103n kh\u00f4ng t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn qu\u00e1 tr\u00ecnh h\u1ea5p thu c\u1ee7a Bisoprolol.<\/li>\n<\/ul>\n<h4>Ph\u00e2n b\u1ed1<\/h4>\n<ul>\n<li>Bisoprolol \u0111\u01b0\u1ee3c g\u1eafn v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng v\u1edbi t\u1ef7 l\u1ec7 kho\u1ea3ng 30%.<\/li>\n<li>Thu\u1ed1c \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau 2-4 gi\u1edd s\u1eed d\u1ee5ng.<\/li>\n<\/ul>\n<h4>Chuy\u1ec3n h\u00f3a<\/h4>\n<ul>\n<li>Qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a Bisoprolol \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n t\u1ea1i gan.<\/li>\n<li>Chuy\u1ec3n h\u00f3a b\u01b0\u1edbc \u0111\u1ea7u qua gan \u00edt n\u00ean sinh kh\u1ea3 d\u1ee5ng cao.<\/li>\n<li>Th\u1eddi gian b\u00e1n th\u1ea3i k\u00e9o d\u00e0i t\u1eeb 10-12 gi\u1edd. \u1ede ng\u01b0\u1eddi cao tu\u1ed5i, th\u1eddi gian b\u00e1n th\u1ea3i c\u00f3 th\u1ec3 d\u00e0i h\u01a1n nh\u01b0ng m\u1ee9c \u0111\u1ed9 t\u00edch l\u0169y trong c\u01a1 th\u1ec3 kh\u00e1c nhau kh\u00f4ng \u0111\u00e1ng k\u1ec3 gi\u1eefa ng\u01b0\u1eddi cao tu\u1ed5i v\u00e0 ng\u01b0\u1eddi tr\u1ebb.<\/li>\n<li>Tr\u00ean b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh th\u1eadn (creatinin th\u1ea5p h\u01a1n 40ml\/ph\u00fat), th\u1eddi gian b\u00e1n th\u1ea3i t\u0103ng g\u1ea5p 3-4 l\u1ea7n.<\/li>\n<li>Tr\u00ean b\u1ec7nh nh\u00e2n x\u01a1 gan, th\u1eddi gian b\u00e1n th\u1ea3i thay \u0111\u1ed5i \u0111\u00e1ng k\u1ec3, th\u01b0\u1eddng t\u1eeb 8,3-21,7 gi\u1edd.<\/li>\n<\/ul>\n<h4>Th\u1ea3i tr\u1eeb<\/h4>\n<p>Bisoprolol \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u. Trong \u0111\u00f3, kho\u1ea3ng m\u1ed9t n\u1eeda \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i, n\u1eeda c\u00f2n l\u1ea1i \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb d\u01b0\u1edbi d\u1ea1ng ch\u1ea5t chuy\u1ec3n h\u00f3a.<\/p>\n<h3>Bihasal 5 tr\u1ecb b\u1ec7nh g\u00ec?<\/h3>\n<p>Bihasal 5mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh nh\u00e2n huy\u1ebft \u00e1p cao, b\u1ec7nh nh\u00e2n m\u1eafc c\u01a1n \u0111au th\u1eaft ng\u1ef1c hay ng\u01b0\u1eddi m\u1eafc suy tim m\u1ea1n t\u00ednh \u1ed5n \u0111\u1ecbnh.<\/p>\n<p>Ngo\u00e0i ra, Bihasal 5mg\u00a0 c\u00f3 th\u1ec3 ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c huy\u1ebft \u00e1p kh\u00e1c lo\u1ea1i v\u00e0 c\u00e1c thu\u1ed1c l\u1ee3i ti\u1ec3u \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p.<\/p>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<h4>S\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb cao huy\u1ebft \u00e1p, gi\u1ea3m t\u00ecnh tr\u1ea1ng \u0111au th\u1eaft ng\u1ef1c<\/h4>\n<ul>\n<li>Li\u1ec1u th\u00f4ng th\u01b0\u1eddng: 5-10 mg\/ng\u00e0y. U\u1ed1ng 1 li\u1ec1u duy nh\u1ea5t.<\/li>\n<li>Li\u1ec1u t\u1ed1i \u0111a: 20 mg\/ng\u00e0y.<\/li>\n<li>\u0110\u1ed1i v\u1edbi ng\u01b0\u1eddi suy gi\u1ea3m ch\u1ee9c n\u0103ng gan th\u1eadn nh\u1eb9 \u0111\u1ebfn v\u1eeba: Kh\u00f4ng c\u1ea7n thi\u1ebft hi\u1ec7u ch\u1ec9nh li\u1ec1u. Li\u1ec1u kh\u1edfi \u0111\u1ea7u c\u00f3 th\u1ec3 l\u00e0 2,5 mg\/ng\u00e0y. C\u1ea7n theo d\u00f5i v\u00e0 ch\u1ec9nh li\u1ec1u cho ph\u00f9 h\u1ee3p v\u1edbi t\u1eebng t\u00ecnh tr\u1ea1ng.<\/li>\n<li>\u0110\u1ed1i v\u1edbi ng\u01b0\u1eddi suy th\u1eadn (creatinin th\u1ea5p h\u01a1n 20ml\/ph\u00fat) v\u00e0 r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng gan n\u1eb7ng: Li\u1ec1u h\u00e0ng ng\u00e0y kh\u00f4ng v\u01b0\u1ee3t qu\u00e1 10 mg.<\/li>\n<\/ul>\n<h4>S\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb suy tim<\/h4>\n<ul>\n<li>Li\u1ec1u kh\u1edfi \u0111\u1ea7u:1,25 mg\/ ng\u00e0y, u\u1ed1ng 1 li\u1ec1u duy nh\u1ea5t.<\/li>\n<li>N\u1ebfu ng\u01b0\u1eddi u\u1ed1ng dung n\u1ea1p \u0111\u01b0\u1ee3c, t\u0103ng li\u1ec1u l\u00ean 2,5 mg\/ng\u00e0y sau 1 tu\u1ea7n, t\u0103ng d\u1ea7n trong 1-4 tu\u1ea7n cho \u0111\u1ebfn li\u1ec1u cao nh\u1ea5t m\u00e0 ng\u01b0\u1eddi b\u1ec7nh c\u00f3 th\u1ec3 dung n\u1ea1p \u0111\u01b0\u1ee3c nh\u01b0ng kh\u00f4ng qu\u00e1 10 mg\/ng\u00e0y.<\/li>\n<li>\u0110\u1ed1i v\u1edbi ng\u01b0\u1eddi cao tu\u1ed5i: Kh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u, tr\u1eeb khi suy gi\u1ea3m ch\u1ee9c n\u0103ng gan th\u1eadn \u0111\u00e1ng k\u1ec3.<\/li>\n<li>N\u1ebfu \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng thu\u1ed1c d\u01b0\u1edbi 1 vi\u00ean\/l\u1ea7n. Ng\u01b0\u1eddi b\u1ec7nh c\u00f3 th\u1ec3 l\u1ef1a ch\u1ecdn thu\u1ed1c v\u1edbi h\u00e0m l\u01b0\u1ee3ng d\u01b0\u1ee3c ch\u1ea5t \u00edt h\u01a1n \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb.<\/li>\n<li>Li\u1ec1u d\u00f9ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh \u0111\u1ec3 ph\u00f9 h\u1ee3p v\u1edbi t\u1eebng ng\u01b0\u1eddi b\u1ec7nh v\u00e0 t\u00ecnh tr\u1ea1ng b\u1ec7nh.<\/li>\n<\/ul>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<ul>\n<li>T\u1ed1t nh\u1ea5t l\u00e0 n\u00ean u\u1ed1ng thu\u1ed1c v\u1edbi nhi\u1ec1u n\u01b0\u1edbc.<\/li>\n<li>N\u00ean s\u1eed d\u1ee5ng thu\u1ed1c v\u00e0o th\u1eddi \u0111i\u1ec3m s\u00e1ng, khi \u0111\u00f3i ho\u1eb7c c\u00f9ng b\u1eefa \u0103n \u0111\u1ec1u \u0111\u01b0\u1ee3c v\u00ec th\u1ee9c \u0103n kh\u00f4ng l\u00e0m \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c.<\/li>\n<\/ul>\n<h3>Thu\u1ed1c Bihasal 5 u\u1ed1ng m\u1ed7i ng\u00e0y c\u00f3 t\u1ed1t kh\u00f4ng?<\/h3>\n<p>Bihasal 5 l\u00e0 thu\u1ed1c ch\u1ec9 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng khi c\u00f3 s\u1ef1 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129. V\u00ec th\u1ebf, ng\u01b0\u1eddi b\u1ec7nh kh\u00f4ng n\u00ean t\u1ef1 \u00fd d\u1eebng thu\u1ed1c, thay \u0111\u1ed5i li\u1ec1u d\u00f9ng ho\u1eb7c kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c theo \u0111\u00fang h\u01b0\u1edbng d\u1eabn. Vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c kh\u00f4ng tu\u00e2n th\u1ee7 kh\u00f4ng nh\u1eefng l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb m\u00e0 c\u00f2n c\u00f3 th\u1ec3 l\u00e0m tr\u1ea7m tr\u1ecdng h\u01a1n t\u00ecnh tr\u1ea1ng b\u1ec7nh.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng Bihasal 5mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Qu\u00e1 m\u1eabn v\u1edbi th\u00e0nh ph\u1ea7n ho\u1ea1t ch\u1ea5t ho\u1eb7c t\u00e1 d\u01b0\u1ee3c c\u00f3 trong thu\u1ed1c, ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi thu\u1ed1c ch\u1eb9n beta adrenergic kh\u00e1c.<\/li>\n<li>Ng\u01b0\u1eddi suy tim c\u1ea5p t\u00ednh, suy tim m\u1ea5t b\u00f9, c\u1ea7n d\u00f9ng thu\u1ed1c ti\u00eam truy\u1ec1n t\u00e1c d\u1ee5ng t\u0103ng co b\u00f3p tim, s\u1ed1c do gi\u1ea3m cung l\u01b0\u1ee3ng tim v\u1edbi huy\u1ebft \u00e1p t\u00e2m thu th\u1ea5p d\u01b0\u1edbi 90mmHg), m\u1ea5t ph\u01b0\u01a1ng h\u01b0\u1edbng, l\u00fa l\u1eabn.<\/li>\n<li>C\u00e1c tr\u01b0\u1eddng h\u1ee3p r\u1ed1i lo\u1ea1n d\u1eabn truy\u1ec1n: Block nh\u0129 th\u1ea5t \u0111\u1ed9 2, \u0111\u1ed9 3.<\/li>\n<li>Ng\u01b0\u1eddi c\u00f3 th\u1ec3 b\u1ecb h\u1ea1 huy\u1ebft \u00e1p nghi\u00eam tr\u1ecdng: huy\u1ebft \u00e1p th\u1ea5p (Huy\u1ebft \u00e1p t\u00e2m thu d\u01b0\u1edbi 100mmHg).<\/li>\n<li>Ng\u01b0\u1eddi m\u1eafc r\u1ed1i lo\u1ea1n cung c\u1ea5p m\u00e1u ngo\u1ea1i vi nghi\u00eam tr\u1ecdng: Raynaud, b\u1ec7nh \u0111\u1ed9ng m\u1ea1ch ngo\u1ea1i vi giai \u0111o\u1ea1n cu\u1ed1i.<\/li>\n<li>Ng\u01b0\u1eddi c\u00f3 nh\u1ecbp tim ch\u1eadm h\u01a1n 50 nh\u1ecbp\/ph\u00fat, suy n\u00fat xoang.<\/li>\n<li>Ng\u01b0\u1eddi nhi\u1ec5m toan chuy\u1ec3n h\u00f3a.<\/li>\n<li>Ng\u01b0\u1eddi \u0111ang c\u00f3 u tuy\u1ebfn th\u01b0\u1ee3ng th\u1eadn ch\u01b0a \u0111i\u1ec1u tr\u1ecb.<\/li>\n<li>S\u1eed d\u1ee5ng Bisoprolol trong khi \u0111ang s\u1eed d\u1ee5ng thu\u1ed1c \u1ee9c ch\u1ebf MAO.<\/li>\n<li>Ng\u01b0\u1eddi m\u1eafc hen n\u1eb7ng, vi\u00eam ph\u1ebf qu\u1ea3n, vi\u00eam \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p m\u1ea1n t\u00ednh ho\u1eb7c m\u1eafc ph\u1ed5i t\u1eafc ngh\u1ebdn m\u00e3n t\u00ednh (COPD).<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng Bihasal 5mg v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Ng\u01b0\u1eddi b\u1ecb suy tim sung huy\u1ebft. \u1ede ng\u01b0\u1eddi suy tim v\u00e0 ph\u1ea3i b\u00f9 th\u00ec c\u1ea7n ph\u1ea3i th\u1eadt c\u1ea9n tr\u1ecdng khi s\u1eed d\u1ee5ng.<\/li>\n<li>Ng\u01b0\u1eddi co th\u1eaft ph\u1ebf qu\u1ea3n n\u00ean th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng do t\u00ednh \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc \u03b2-adrenergic c\u1ee7a Bisoprolol.<\/li>\n<li>Tr\u01b0\u1edbc khi ph\u1eabu thu\u1eadt, n\u00ean ng\u1eebng s\u1eed d\u1ee5ng Bisoprolol t\u1ed1i thi\u1ec3u tr\u01b0\u1edbc 2 ng\u00e0y.<\/li>\n<li>N\u00ean s\u1eed d\u1ee5ng Bisoprolol th\u1eadt th\u1eadn trognj khi \u0111ang s\u1eed d\u1ee5ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng do thu\u1ed1c l\u00e0m \u1ea9n \u0111i c\u00e1c bi\u1ec3u hi\u1ec7n h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft.<\/li>\n<li>Kh\u00f4ng n\u00ean d\u1eebng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t ho\u1eb7c t\u1ef1 \u00fd \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u n\u1ebfu kh\u00f4ng c\u00f3 s\u1ef1 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a c\u00e1n b\u1ed9 y t\u1ebf v\u00ec s\u1ebd l\u00e0m n\u1eb7ng th\u00eam t\u00ecnh tr\u1ea1ng \u0111au th\u1eaft ng\u1ef1c, nh\u1ed3i m\u00e1u c\u01a1 tim hay lo\u1ea1n nh\u1ecbp tim.<\/li>\n<li>Ch\u1ec9 s\u1eed d\u1ee5ng thu\u1ed1c khi c\u00f3 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129 ho\u1eb7c c\u00e1n b\u1ed9 y t\u1ebf.<\/li>\n<\/ul>\n<h3>Thu\u1ed1c Bihasal 5 v\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<h4>Th\u01b0\u1eddng g\u1eb7p<\/h4>\n<ul>\n<li>Tr\u00ean th\u1ea7n kinh: M\u1ec7t m\u1ecfi, cho\u00e1ng v\u00e1ng, nh\u1ee9c \u0111\u1ea7u, ra m\u1ed3 h\u00f4i, r\u1ed1i lo\u1ea1n gi\u1ea5c ng\u1ee7, lo l\u1eafng, gi\u1ea3m kh\u1ea3 n\u0103ng t\u1eadp trung. Th\u01b0\u1eddng xu\u1ea5t hi\u1ec7n khi m\u1edbi d\u00f9ng thu\u1ed1c ho\u1eb7c sau t\u0103ng li\u1ec1u, c\u00f3 th\u1ec3 m\u1ea5t tri\u1ec7u ch\u1ee9ng sau 1-2 tu\u1ea7n.<\/li>\n<\/ul>\n<h4>\u00cdt g\u1eb7p<\/h4>\n<ul>\n<li>Tr\u00ean th\u1ea7n kinh: Bu\u1ed3n ng\u1ee7, lo \u00e2u, b\u1ed3n ch\u1ed3n, tr\u00ed nh\u1edb suy gi\u1ea3m, kh\u1ea3 n\u0103ng c\u1ea3m gi\u00e1c k\u00e9m, kh\u00f4 mi\u1ec7ng, run ho\u1eb7c co gi\u1eadt, co c\u1ee9ng b\u1ee5ng, \u0111au c\u01a1 kh\u1edbp.<\/li>\n<li>Tr\u00ean ti\u00eau h\u00f3a: Ti\u00eau ch\u1ea3y, t\u00e1o b\u00f3n, \u0111au d\u1ea1 d\u00e0y, \u0111au tr\u00ean r\u1ed1n, bu\u1ed3n n\u00f4n, n\u00f4n.<\/li>\n<li>Tr\u00ean t\u00e2m th\u1ea7n: M\u1ea5t ng\u1ee7, tr\u1ea7m c\u1ea9m, hay g\u1eb7p \u00e1c m\u1ed9ng.<\/li>\n<li>Tr\u00ean tim m\u1ea1ch: M\u1ea1ch ch\u1eadm, r\u1ed1i lo\u1ea1n d\u1eabn truy\u1ec1n nh\u0129 th\u1ea5t, huy\u1ebft \u00e1p h\u1ea1, t\u00ea v\u00e0 l\u1ea1nh \u0111\u1ea7u chi.<\/li>\n<\/ul>\n<h4>Hi\u1ebfm g\u1eb7p<\/h4>\n<ul>\n<li>Tr\u00ean ti\u1ebft ni\u1ec7u sinh d\u1ee5c: Vi\u00eam b\u00e0ng quang, gi\u1ea3m ham mu\u1ed1n sinh d\u1ee5c, \u0111au qu\u1eb7n \u1edf th\u1eadn.<\/li>\n<li>Tr\u00ean h\u00f4 h\u1ea5p: Ho, kh\u00f3 th\u1edf, co th\u1eaft ph\u1ebf qu\u1ea3n..<\/li>\n<li>Tr\u00ean da v\u00e0 m\u00f4: N\u1ed5i ban, ng\u1ee9a, s\u01b0ng, \u0111\u1ecf, da bong tr\u00f3c, r\u1ee5ng t\u00f3c.<\/li>\n<li>Ngo\u00e0i ra, \u1edf b\u1ec7nh nh\u00e2n \u0111i kh\u1eadp khi\u1ec5ng v\u00e0 m\u1eafc h\u1ed9i ch\u1ee9ng Raynaud, khi m\u1edbi s\u1eed d\u1ee5ng thu\u1ed1c s\u1ebd l\u00e0m c\u00e1c tri\u1ec7u ch\u1ee9ng n\u1eb7ng h\u01a1n, suy c\u01a1 tim c\u00f3 th\u1ec3 nghi\u00eam tr\u1ecdng h\u01a1n.<\/li>\n<\/ul>\n<p>\u1ede b\u1ec7nh nh\u00e2n cao tu\u1ed5i, m\u1eafc \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, c\u00e1c d\u1ea5u hi\u1ec7u b\u1ec7nh nh\u01b0 nh\u1ecbp tim nhanh c\u00f3 th\u1ec3 kh\u00f4ng xu\u1ea5t hi\u1ec7n.<\/p>\n<p>N\u1ebfu xu\u1ea5t hi\u1ec7n b\u1ea5t k\u00ec d\u1ea5u hi\u1ec7u b\u1ea5t th\u01b0\u1eddng n\u00e0o trong th\u1eddi gian s\u1eed d\u1ee5ng thu\u1ed1c, c\u1ea7n d\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c ngay l\u1eadp t\u1ee9c, th\u00f4ng b\u00e1o cho ng\u01b0\u1eddi c\u00f3 chuy\u00ean m\u00f4n \u0111\u1ec3 \u0111\u01b0\u1ee3c h\u1ed7 tr\u1ee3 k\u1ecbp th\u1eddi.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h3>\n<ul>\n<li>Kh\u00f4ng n\u00ean ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c ch\u1eb9n \u03b2 kh\u00e1c do c\u00f9ng c\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng.<\/li>\n<li>S\u1eed d\u1ee5ng Bisoprolol c\u00f9ng c\u00e1c thu\u1ed1c ch\u1ee9a resepin, clonidin, guanethidin hay alpha-methyldopa s\u1ebd l\u00e0m gi\u1ea3m nh\u1ecbp tim. Do \u0111\u00f3 c\u1ea7n th\u1eadn tr\u1ecdng trong qu\u00e1 tr\u00ecnh s\u1eed d\u1ee5ng.<\/li>\n<li>Bisoprolol khi s\u1eed d\u1ee5ng c\u00f9ng c\u00e1c thu\u1ed1c ch\u1eb9n calci nh\u01b0 erapamil, Diltiazem, Nifedipine ho\u1eb7c thu\u1ed1c ch\u1ed1ng lo\u1ea1n nh\u1ecbp disopyramid c\u00f3 th\u1ec3 l\u00e0m h\u1ea1 huy\u1ebft \u00e1p, ch\u1eadm nh\u1ecbp, lo\u1ea1n nh\u1ecbp ho\u1eb7c suy tim.<\/li>\n<li>Kh\u00f4ng s\u1eed d\u1ee5ng Bisoprolol c\u00f9ng Rifampicin do l\u00e0m t\u0103ng th\u1ea3i tr\u1eeb thu\u1ed1c. Tuy nhi\u00ean vi\u1ec7c \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u Bisoprolol l\u00e0 kh\u00f4ng th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft.<\/li>\n<li>S\u1eed d\u1ee5ng Bisoprolol c\u00f9ng insulin v\u00e0 c\u00e1c thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft kh\u00e1c do c\u00f3 th\u1ec3\u00a0 l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft c\u1ee7a ch\u00fang. Nh\u01b0ng c\u00f3 th\u1ec3 g\u00e2y che l\u1ea5p bi\u1ec3u hi\u1ec7n h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, \u0111i\u1ec3n h\u00ecnh l\u00e0 nh\u1ecbp tim nhanh. Khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi, c\u1ea7n theo d\u00f5i \u0111\u01b0\u1eddng huy\u1ebft \u0111\u1ec1u \u0111\u1eb7n.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng Bihasal 5mg cho \u0111\u1ed1i t\u01b0\u1ee3ng n\u00e0y do c\u00f3 th\u1ec3 g\u00e2y ch\u1eadm nh\u1ecbp tim, h\u1ea1 huy\u1ebft \u00e1p v\u00e0 \u0111\u01b0\u1eddng huy\u1ebft tr\u00ean tr\u1ebb. Ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n\u00a0 ng\u01b0ng d\u00f9ng thu\u1ed1c \u00edt nh\u1ea5t 3 ng\u00e0y tr\u01b0\u1edbc sinh. N\u1ebfu kh\u00f4ng, tr\u1ebb ph\u1ea3i \u0111\u01b0\u1ee3c theo d\u00f5i sau sinh trong 2-3 ng\u00e0y sau sinh.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Bihasal 5mg c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c, \u0111\u1eb7c bi\u1ec7t l\u00e0 th\u1eddi \u0111i\u1ec3m m\u1edbi \u0111i\u1ec1u tr\u1ecb v\u00e0 khi s\u1eed d\u1ee5ng c\u00f9ng r\u01b0\u1ee3u do t\u00e1c d\u1ee5ng l\u00e0m h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a thu\u1ed1c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<ul>\n<li>Qu\u00e1 li\u1ec1u Bihasal 5 g\u00e2y bi\u1ec3u hi\u1ec7n nh\u1ecbp tim ch\u1eadm, c\u00f3 th\u1ec3 k\u00e8m theo h\u1ea1 huy\u1ebft \u00e1p. N\u1ebfu n\u1eb7ng c\u00f3 th\u1ec3 g\u00e2y s\u1ea3ng, h\u00f4n m\u00ea, co gi\u1eadt, th\u1eadm ch\u00ed ng\u1eebng h\u00f4 h\u1ea5p.<\/li>\n<li>Ngo\u00e0i ra, c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n suy tim sung huy\u1ebft, h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, co th\u1eaft ph\u1ebf qu\u1ea3n. \u0110\u1eb7c bi\u1ec7t l\u00e0 ng\u01b0\u1eddi \u0111\u00e3 c\u00f3 ti\u1ec1n s\u1eed m\u1eafc b\u1ec7nh n\u00e0y.<\/li>\n<li>Khi x\u1ea3y ra qu\u00e1 li\u1ec1u, ph\u1ea3i ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c ngay v\u00e0 k\u1ebft h\u1ee3p v\u1edbi \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 tri\u1ec7u ch\u1ee9ng.<\/li>\n<\/ul>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n trong h\u1ed9p k\u00edn, tho\u00e1ng m\u00e1t, tr\u00e1nh n\u01a1i \u1ea9m th\u1ea5p, nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30 \u0111\u1ed9 C.<\/p>\n<h2>Bihasal 5 gi\u00e1 bao nhi\u00eau? B\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>\u0110\u1ec3 mua \u0111\u01b0\u1ee3c s\u1ea3n ph\u1ea9m Bihasal 5, Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 mang \u0111\u01a1n thu\u1ed1c \u0111\u1ebfn c\u00e1c \u0111\u1ecba ch\u1ec9 kinh doanh d\u01b0\u1ee3c ph\u1ea9m tr\u00ean to\u00e0n qu\u1ed1c. Kh\u00e1ch h\u00e0ng n\u00ean t\u00ecm hi\u1ec3u v\u00e0 l\u1ef1a ch\u1ecdn c\u00e1c \u0111\u1ecba \u0111i\u1ec3m uy t\u00edn \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o mua \u0111\u01b0\u1ee3c thu\u1ed1c an to\u00e0n, ch\u1ea5t l\u01b0\u1ee3ng, c\u00f3 ngu\u1ed3n g\u1ed1c r\u00f5 r\u00e0ng.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Bihasal 5<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o th\u00eam c\u00e1c thu\u1ed1c kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/bisoprolol-stada-5mg\/\">Bisoprolol Stada<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH LD Stada &#8211; Vi\u1ec7t Nam. V\u1edbi th\u00e0nh ph\u1ea7n ch\u1ee9a Bisoprolol fumarat 5 mg, thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p, \u0111i\u1ec1u tr\u1ecb \u0111au th\u1eaft ng\u1ef1c \u1ed5n \u0111\u1ecbnh v\u00e0 ph\u1ed1i h\u1ee3p \u0111i\u1ec1u tr\u1ecb cho b\u1ec7nh nh\u00e2n suy tim m\u1ea1n.<\/p>\n<p>Vi\u1ec7c l\u1ef1a ch\u1ecdn s\u1ea3n ph\u1ea9m ph\u1ee5 thu\u1ed9c v\u00e0o ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129 v\u00e0 s\u1ef1 s\u1eb5n c\u00f3 t\u1ea1i nh\u00e0 thu\u1ed1c. B\u1ec7nh nh\u00e2n kh\u00f4ng n\u00ean t\u1ef1 \u00fd thay \u0111\u1ed5i gi\u1eefa c\u00e1c bi\u1ec7t d\u01b0\u1ee3c m\u00e0 kh\u00f4ng c\u00f3 \u00fd ki\u1ebfn c\u1ee7a chuy\u00ean gia y t\u1ebf.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i file <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/HDSD-Bihasal-5-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>.<\/li>\n<li>Bakheit AH, Ali R, Alshahrani AD, El-Azab AS, Bisoprolol: A comprehensive profile. Profiles Drug Subst Excip Relat Methodol truy c\u1eadp ng\u00e0y 06 th\u00e1ng 09 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33461700\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33461700\/<\/a>.<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p><span style=\"font-weight: 400;\">Bihasal 5mg ch\u1ee9a th\u00e0nh ph\u1ea7n l\u00e0 Bisoprolol fumarat, m\u1ed9t ho\u1ea1t ch\u1ea5t c\u00f3 t\u00e1c d\u1ee5ng tr\u00ean tim m\u1ea1ch nh\u1edd c\u01a1 ch\u1ebf ch\u1eb9n th\u1ee5 th\u1ec3\u00a0 \u03b21- adrenergic, c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m h\u1ea1 huy\u1ebft \u00e1p tr\u00ean ng\u01b0\u1eddi m\u1eafc huy\u1ebft \u00e1p cao, \u1ed5n \u0111\u1ecbnh c\u01a1n \u0111au th\u1eaft ng\u1ef1c v\u00e0 t\u00ecnh tr\u1ea1ng suy tim m\u1ea1n t\u00ednh.<\/span><\/p>\n","protected":false},"author":1,"featured_media":137252,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-137242","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/137242","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=137242"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/137252"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=137242"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=137242"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=137242"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}