{"id":13702,"date":"2019-07-11T09:40:52","date_gmt":"2019-07-11T02:40:52","guid":{"rendered":"https:\/\/www.vnras.com\/drug\/?post_type=product&#038;p=13702"},"modified":"2025-07-24T14:40:31","modified_gmt":"2025-07-24T07:40:31","slug":"imbruvica","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/imbruvica\/","title":{"rendered":"Imbruvica"},"content":{"rendered":"<p>Trong b\u00e0i vi\u1ebft n\u00e0y,\u00a0<a href=\"https:\/\/www.vnras.com\/drug\/\">nh\u00e0 thu\u1ed1c L\u01b0u V\u0103n Ho\u00e0ng<\/a>\u00a0gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m\u00a0<strong><a href=\"https:\/\/www.vnras.com\/drug\/imbruvica\">thu\u1ed1c\u00a0Imbruvica<\/a><\/strong>\u00a0\u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u00f4ng ty Catalent Cts, llc &#8211; M\u1ef9, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN3-44-18, \u0111\u01b0\u1ee3c \u0111\u0103ng k\u00fd b\u1edfi c\u00f4ng ty Janssen-Cilag., ltd<\/p>\n<h2>Imbruvica l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<p><strong>Thu\u1ed1c Imbruvica<\/strong>\u00a0l\u00e0 thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb u lympho t\u1ebf b\u00e0o v\u1ecf, b\u1ec7nh b\u1ea1ch c\u1ea7u m\u1ea1n t\u00ednh v\u00e0 m\u1ed9t s\u1ed1 b\u1ec7nh kh\u00e1c c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Ibrutinib v\u1edbi h\u00e0m l\u01b0\u1ee3ng 140 mg; ngo\u00e0i ra c\u00f2n c\u00f3 m\u1ed9t s\u1ed1 t\u00e1 d\u01b0\u1ee3c kh\u00e1c th\u00eam v\u00e0o v\u1eeba \u0111\u1ee7 1 vi\u00ean<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: vi\u00ean nang c\u1ee9ng<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: m\u1ed7i h\u1ed9p thu\u1ed1c Imbruvica 90 vi\u00ean ho\u1eb7c 120 vi\u00ean<\/p>\n<p>B\u1ea3o qu\u1ea3n thu\u1ed1c Imbruvica \u1edf nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30 \u0111\u1ed9 C, tr\u00e1nh \u00e1nh s\u00e1ng m\u1eb7t tr\u1eddi chi\u1ebfu tr\u1ef1c ti\u1ebfp, \u0111\u1ec3 xa t\u1ea7m v\u1edbi c\u1ee7a tr\u1ebb em.<\/p>\n<h2>Thu\u1ed1c\u00a0Imbruvica gi\u00e1 bao nhi\u00eau? B\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p><strong>Thu\u1ed1c Imbruvica<\/strong> gi\u00e1 800.000 \u0111\u1ed3ng 1 h\u1ed9p b\u00e1n t\u1ea1i nh\u00e0 thu\u1ed1c L\u01b0u V\u0103n Ho\u00e0ng, ch\u00fang t\u00f4i giao h\u00e0ng to\u00e0n qu\u1ed1c.<\/p>\n<p>K\u00ednh m\u1eddi qu\u00fd kh\u00e1ch xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<\/p>\n<ul>\n<li><a href=\"https:\/\/www.vnras.com\/drug\/endoxan\">thu\u1ed1c\u00a0Endoxan<\/a>\u00a0\u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Baxter Oncology GmbH, \u0110\u1ee9c<\/li>\n<li><a href=\"https:\/\/www.vnras.com\/drug\/pegasys\">thu\u1ed1c Pegasys<\/a>\u00a0\u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty F. Hoffmann-La Roche.<\/li>\n<li>thu\u1ed1c\u00a0<a href=\"https:\/\/www.vnras.com\/drug\/hyxure\">Hyxure<\/a>\u00a0\u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m\u00a0\u0110\u1ea1t Vi Ph\u00fa<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Imbruvica c\u00f3 t\u00e1c d\u1ee5ng g\u00ec?<\/h2>\n<p>Thu\u1ed1c Imbruvica c\u00f3 t\u00e1c d\u1ee5ng trong:<\/p>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh u lympho t\u1ebf b\u00e0o v\u1ecf<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh b\u1ea1ch c\u1ea7u m\u1ea1n t\u00ednh d\u00f2ng lympho.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb k\u1ebft h\u1ee3p v\u1edbi bendamustine &amp; rituximab.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh macroglobulinemia waldenstr\u00f6m (wm)\u00a0m\u00e0 b\u1ec7nh nh\u00e2n \u0111\u00e3 s\u1eed d\u1ee5ng t\u1ed1i thi\u1ec3u 1 bi\u1ec7n ph\u00e1p \u0111i\u1ec1u tr\u1ecb tr\u01b0\u1edbc \u0111\u00f3.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng thu\u1ed1c Imbruvica nh\u01b0 th\u1ebf n\u00e0o?<\/h2>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb u lympho t\u1ebf b\u00e0o v\u1ecf: u\u1ed1ng 4 vi\u00ean m\u1ed7i ng\u00e0y m\u1ed9t l\u1ea7n.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb b\u1ea1ch c\u1ea7u m\u1ea1n t\u00ednh d\u00f2ng lympho v\u00e0 b\u00eanh wm: u\u1ed1ng 3 vi\u00ean m\u1ed7i ng\u00e0y m\u1ed9t l\u1ea7n.<\/li>\n<li>Ch\u00fa \u00fd:<\/li>\n<\/ul>\n<p>+ \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n suy th\u1eadn n\u1eb7ng, ch\u1ec9 s\u1eed d\u1ee5ng khi t\u00e1c d\u1ee5ng v\u01b0\u1ee3t tr\u1ed9i so v\u1edbi nguy c\u01a1.<\/p>\n<p>+ \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n suy gan nh\u1eb9: u\u1ed1ng 2 vi\u00ean m\u1ed7i ng\u00e0y<\/p>\n<p>+ \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n suy gan trung b\u00ecnh : u\u1ed1ng 1 vi\u00ean m\u1ed7i ng\u00e0y<\/p>\n<p>+ kh\u00f4ng s\u1eed d\u1ee5ng \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n suy gan n\u1eb7ng.<\/p>\n<ul>\n<li>Khi k\u1ebft h\u1ee3p thu\u1ed1c \u1ee9c ch\u1ebf cyp3a4 trung b\u00ecnh: u\u1ed1ng 2 vi\u00ean m\u1ed9t l\u1ea7n m\u1ed7i ng\u00e0y<\/li>\n<li>Khi k\u1ebft h\u1ee3p thu\u1ed1c \u1ee9c ch\u1ebf cyp3a4 m\u1ea1nh: 2 vi\u00ean, 1 l\u1ea7n m\u1ed7i ng\u00e0y ho\u1eb7c t\u1ea1m ng\u1eebng \u0111\u1ebfn 7 ng\u00e0y.<\/li>\n<li>T\u1ea1m ng\u1eebng \u0111i\u1ec1u tr\u1ecb trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p<\/li>\n<\/ul>\n<p>+ ti\u1ebfn tri\u1ec3n kh\u00f4ng t\u1ed1t c\u1ee7a \u0111\u1ed9c t\u00ednh kh\u00f4ng ph\u1ea3i huy\u1ebft h\u1ecdc t\u1eeb\u00a0\u0111\u1ed9 3 tr\u1edf l\u00ean<\/p>\n<p>+ hi\u1ec7n t\u01b0\u1ee3ng gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh c\u00f3 k\u00e8m theo nhi\u1ec5m tr\u00f9ng ho\u1eb7c s\u1ed1t t\u1eeb \u0111\u1ed9 3 tr\u1edf l\u00ean<\/p>\n<p>+ \u0111\u1ed9c t\u00ednh huy\u1ebft h\u1ecdc \u0111\u1ed9 4.<\/p>\n<p>+ \u0111i\u1ec1u tr\u1ecb v\u1edbi li\u1ec1u kh\u1edfi \u0111\u1ea7u khi \u0111\u1ed9c t\u00ednh tr\u1edf v\u1ec1 \u0111\u1ed9 1<\/p>\n<p>+ \u0111\u1ed9c t\u00ednh t\u00e1i ph\u00e1t: gi\u1ea3m \u0111i 1 vi\u00ean m\u1ed7i ng\u00e0y<\/p>\n<p>+ \u0111\u1ed9c t\u00ednh t\u00e1i ph\u00e1t ho\u1eb7c k\u00e9o d\u00e0i sau 2 l\u1ea7n gi\u1ea3m li\u1ec1u th\u00ec ti\u1ebfn h\u00e0nh ng\u1eebng \u0111i\u1ec1u tr\u1ecb.<\/p>\n<ul>\n<li>N\u1ebfu qu\u00ean li\u1ec1u th\u00ec hay u\u1ed1ng v\u00e0o c\u00f9ng ng\u00e0y s\u1edbm nh\u1ea5t c\u00f3 th\u1ec3 v\u00e0 kh\u00f4ng u\u1ed1ng b\u00f9 li\u1ec1u \u0111\u00e3 qu\u00ean<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Imbruvica khi n\u00e0o?<\/h2>\n<ul>\n<li>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Imbruvica cho ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u00ec th\u00e0nh ph\u1ea7n n\u00e0o c\u00f3 trong thu\u1ed1c.\u00a0C\u1ee5 th\u1ec3 l\u00e0 ho\u1ea1t ch\u1ea5t azithromycin<\/li>\n<li>Kh\u00f4ng s\u1eed d\u1ee5ng \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n suy gan n\u1eb7ng.<\/li>\n<\/ul>\n<h2>Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng thu\u1ed1c Imbruvica<\/h2>\n<ul>\n<li>B\u1ec7nh nh\u00e2n b\u1ecb rung nh\u0129 c\u1ea7n \u0111i\u1ec1u tr\u1ecb ch\u1ed1ng \u0111\u00f4ng ph\u1ea3i ch\u1ecdn bi\u1ec7n ph\u00e1p kh\u00e1c thay th\u1ebf Imbruvica.<\/li>\n<li>D\u1eebng \u0111i\u1ec1u tr\u1ecb t\u1ed1i thi\u1ec3u 3 \u2013 7 ng\u00e0y tr\u01b0\u1edbc v\u00e0 sau ph\u1eabu thu\u1eadt.<\/li>\n<li>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ra ng\u01b0ng t\u1eadp b\u1ea1ch c\u1ea7u, d\u1eebng s\u1eed d\u1ee5ng n\u1ebfu lympho c\u00f3 n\u1ed3ng \u0111\u1ed9 l\u1edbn h\u01a1n 400 000\/mcl<\/li>\n<li>Ngo\u00e0i ra thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ra: b\u1ec7nh n\u00e3o ch\u1ea5t tr\u1eafng \u0111a \u1ed5 ti\u1ebfn, b\u1ec7nh ph\u1ed5i k\u1ebd, thuy\u00ean t\u1eafc huy\u1ebft kh\u1ed1i, h\u1ed9i ch\u1ee9ng ly gi\u1ea3i kh\u1ed1i u, t\u00e1i ho\u1ea1t vi\u00eam gan b.<\/li>\n<li>Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, b\u1ec7nh nh\u00e2n c\u1ea7n tu\u00e2n th\u1ee7 theo ch\u1ec9 \u0111\u1ecbnh, kh\u00f4ng t\u1ef1 \u00fd t\u0103ng hay gi\u1ea3m l\u01b0\u1ee3ng thu\u1ed1c u\u1ed1ng \u0111\u1ec3 nhanh c\u00f3 hi\u1ec7u qu\u1ea3.<\/li>\n<li>N\u1ebfu b\u1ea1n c\u00f3 b\u1ec7nh m\u1ea1n t\u00ednh y\u00eau c\u1ea7u d\u00f9ng thu\u1ed1c k\u00e9o d\u00e0i nh\u01b0 b\u1ec7nh tim m\u1ea1ch, d\u1ecb \u1ee9ng\u2026 h\u00e3y cho b\u00e1c s\u0129 bi\u1ebft \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n v\u00e0 thay \u0111\u1ed5i li\u1ec1u d\u00f9ng n\u1ebfu c\u1ea7n thi\u1ebft.<\/li>\n<li>Trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb, b\u1ec7nh nh\u00e2n c\u1ea7n h\u1ea1n ch\u1ebf t\u1ed1i \u0111a c\u00e1c lo\u1ea1i th\u1ee9c \u0103n hay \u0111\u1ed3 u\u1ed1ng c\u00f3 ch\u1ee9a c\u1ed3n ho\u1eb7c ch\u1ea5t k\u00edch th\u00edch.<\/li>\n<li>C\u1ea7n tham kh\u1ea3o \u00fd ki\u1ebfn c\u1ee7a b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb tr\u01b0\u1edbc khi quy\u1ebft \u0111\u1ecbnh ng\u1eebng \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c.<\/li>\n<\/ul>\n<p>L\u01b0u \u00fd:<\/p>\n<ul>\n<li>V\u1edbi c\u00e1c thu\u1ed1c h\u1ebft h\u1ea1n s\u1eed d\u1ee5ng ho\u1eb7c xu\u1ea5t hi\u1ec7n c\u00e1c bi\u1ec3u hi\u1ec7n l\u1ea1 tr\u00ean thu\u1ed1c nh\u01b0 m\u1ed1c, \u0111\u1ed5i m\u00e0u thu\u1ed1c, ch\u1ea3y n\u01b0\u1edbc th\u00ec kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng ti\u1ebfp.<\/li>\n<li>Tr\u00e1nh \u0111\u1ec3 thu\u1ed1c \u1edf nh\u1eefng n\u01a1i c\u00f3 \u00e1nh n\u1eafng tr\u1ef1c ti\u1ebfp chi\u1ebfu v\u00e0o ho\u1eb7c n\u01a1i c\u00f3 \u0111\u1ed9 \u1ea9m cao.<\/li>\n<li>Kh\u00f4ng \u0111\u1ec3 thu\u1ed1c g\u1ea7n n\u01a1i tr\u1ebb em ch\u01a1i \u0111\u00f9a, tr\u00e1nh tr\u01b0\u1eddng h\u1ee3p tr\u1ebb em c\u00f3 th\u1ec3 ngh\u1ecbch v\u00e0 v\u00f4 t\u00ecnh u\u1ed1ng ph\u1ea3i.<\/li>\n<\/ul>\n<h2>T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n khi s\u1eed d\u1ee5ng thu\u1ed1c Imbruvica<\/h2>\n<p>Trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb b\u1eb1ng thu\u1ed1c n\u00e0y, b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 g\u1eb7p ph\u1ea3i m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n:<\/p>\n<p>&#8211; M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 d\u1ec5 g\u1eb7p nh\u1ea5t c\u1ee7a thu\u1ed1c l\u00e0:<\/p>\n<ul>\n<li>Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p: bao g\u1ed3m c\u1ea3 nhi\u1ec5m tr\u00f9ng h\u00f4 h\u1ea5p tr\u00ean (vi\u00eam m\u0169i, vi\u00eam xoang) v\u00e0 nhi\u1ec5m tr\u00f9ng h\u00f4 h\u1ea5p d\u01b0\u1edbi (vi\u00eam ph\u1ed5i, vi\u00eam ph\u1ebf qu\u1ea3n)<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n da<\/li>\n<li>R\u1ed1i lo\u1ea1n c\u00e1c y\u1ebfu t\u1ed1 trong m\u00e1u: s\u1ed1 l\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u trung t\u00ednh gi\u1ea3m, s\u1ed1 l\u01b0\u1ee3ng ti\u1ec3u c\u1ea7u gi\u1ea3m;<\/li>\n<li>C\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n ch\u1ea3y m\u00e1u ho\u1eb7c c\u00e1c v\u1ebft b\u1ea7m<\/li>\n<li>R\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a nh\u1eb9: n\u00f4n nao, n\u00f4n m\u1eeda, \u0111i ngo\u00e0i, t\u00e1o b\u00f3n<\/li>\n<li>Nh\u1ee9c \u0111\u1ea7u, \u0111au m\u1ecfi kh\u1edbp, c\u1ee9ng c\u01a1, co c\u01a1, \u0111au nh\u1ee9c x\u01b0\u01a1ng<\/li>\n<\/ul>\n<p>&#8211; M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p c\u1ee7a thu\u1ed1c:<\/p>\n<ul>\n<li>Nhi\u1ec5m tr\u00f9ng m\u00e1u, nhi\u1ec5m tr\u00f9ng ti\u1ebft ni\u1ec7u<\/li>\n<li>Xu\u1ea5t hi\u1ec7n U tr\u00ean da kh\u00f4ng h\u1eafc t\u1ed1t, U t\u1ebf b\u00e0o \u0111\u00e1y<\/li>\n<li>R\u1ed1i lo\u1ea1n c\u00e1c y\u1ebfu t\u1ed1 trong m\u00e1u<\/li>\n<li>M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 tr\u00ean tim: rung nh\u0129, nh\u1ecbp nhanh t\u00e2m th\u1ea5t, huy\u1ebft \u00e1p cao<\/li>\n<li>Tr\u00ean da: xu\u1ea5t hi\u1ec7n m\u1ec1 \u0111ay, m\u1ea9n ng\u1ee9a, n\u1ed5i ban.<\/li>\n<\/ul>\n<p>B\u1ec7nh nh\u00e2n c\u1ea7n th\u00f4ng b\u00e1o ngay cho b\u00e1c s\u0129, d\u01b0\u1ee3c s\u0129 c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c Imbruvica.<\/p>\n<h2>Ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c c\u00f3 d\u00f9ng thu\u1ed1c Imbruvica \u0111\u01b0\u1ee3c kh\u00f4ng?<\/h2>\n<p>Thu\u1ed1c Imbruvica c\u00f3 th\u1ec3 d\u00f9ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c do thu\u1ed1c kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn t\u00e2m th\u1ea7n v\u00e0 s\u1ef1 t\u1eadp trung.<\/p>\n<h2>Ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa c\u00f3 d\u00f9ng thu\u1ed1c Imbruvica \u0111\u01b0\u1ee3c kh\u00f4ng?<\/h2>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Imbruvica n\u1ebfu b\u1ea1n \u0111ang mang thai. N\u00f3 c\u00f3 th\u1ec3 g\u00e2y h\u1ea1i cho thai nhi. B\u1ea1n c\u00f3 th\u1ec3 c\u1ea7n ph\u1ea3i c\u00f3 m\u1ed9t x\u00e9t nghi\u1ec7m th\u1eed thai \u00e2m t\u00ednh tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb n\u00e0y.<\/p>\n<p>T\u1ed1t nh\u1ea5t n\u00ean th\u1eadn tr\u1ecdng n\u1ebfu \u0111ang c\u00e2n nh\u1eafc s\u1eed d\u1ee5ng thu\u1ed1c cho ph\u1ee5 n\u1eef c\u00f3 thai ho\u1eb7c ph\u1ee5 n\u1eef \u0111ang trong th\u1eddi gian cho con b\u00fa. \u0110\u1ec3 c\u00f3 quy\u1ebft \u0111\u1ecbnh ch\u00ednh x\u00e1c, b\u1ec7nh nh\u00e2n n\u00ean tham kh\u1ea3o \u00fd ki\u1ebfn c\u1ee7a b\u00e1c s\u0129 tr\u01b0\u1edbc khi quy\u1ebft \u0111\u1ecbnh s\u1eed d\u1ee5ng thu\u1ed1c.<\/p>\n<h2>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h2>\n<ul>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf cyp3a4 m\u1ea1nh c\u00f3 th\u1ec3 g\u00e2y t\u0103ng n\u1ed3ng \u0111\u1ed9 ibrutinib huy\u1ebft t\u01b0\u01a1ng.<\/li>\n<li>Thu\u1ed1c c\u1ea3m \u1ee9ng cyp3a4 trung b\u00ecnh &#8211; m\u1ea1nh\u00a0c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 ibrutinib huy\u1ebft t\u01b0\u01a1ng.<\/li>\n<li>Thu\u1ed1c c\u1ea3m \u1ee9ng cyp3a4\u00a0nh\u1eb9 c\u00f3 nguy c\u01a1 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3.<\/li>\n<li>Ibrutinib c\u00f3 th\u1ec3 \u1ee9c ch\u1ebf p-gp v\u00e0 bcrp \u1edf ru\u1ed9t v\u00e0 bcrp \u1edf gan.<\/li>\n<li>\u0110i\u1ec1u c\u1ea7n l\u00e0m l\u00e0 b\u1ec7nh nh\u00e2n h\u00e3y li\u1ec7t k\u00ea c\u00e1c thu\u1ed1c ho\u1eb7c th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng \u0111ang s\u1eed d\u1ee5ng v\u00e0o th\u1eddi \u0111i\u1ec3m n\u00e0y \u0111\u1ec3 b\u00e1c s\u0129 c\u00f3 th\u1ec3 bi\u1ebft v\u00e0 t\u01b0 v\u1ea5n \u0111\u1ec3 tr\u00e1nh t\u01b0\u01a1ng t\u00e1c thu\u1ed1c kh\u00f4ng mong mu\u1ed1n.<\/li>\n<\/ul>\n<h2>Qu\u00e1 li\u1ec1u, qu\u00ean li\u1ec1u v\u00e0 c\u00e1ch x\u1eed tr\u00ed<\/h2>\n<p>Tri\u1ec7u ch\u1ee9ng: khi u\u1ed1ng qu\u00e1 li\u1ec1u thu\u1ed1c, b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 g\u1eb7p c\u00e1c \u0111\u1ed9c t\u00ednh tr\u00ean th\u1eadn, gan ho\u1eb7c g\u1eb7p m\u1ed9t s\u1ed1 bi\u1ec3u hi\u1ec7n gi\u1ed1ng v\u1edbi t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u1ee7a thu\u1ed1c.<\/p>\n<p>X\u1eed tr\u00ed: theo d\u00f5i n\u1ebfu c\u00e1c bi\u1ec3u hi\u1ec7n nh\u1eb9; tuy nhi\u00ean n\u00ean \u0111\u1ec1 ph\u00f2ng v\u00ec s\u1ed1c ph\u1ea3n v\u1ec7 th\u01b0\u1eddng c\u00f3 di\u1ec5n bi\u1ebfn r\u1ea5t nhanh. B\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c \u0111\u01b0a \u0111\u1ebfn b\u1ec7nh vi\u1ec7n s\u1edbm \u0111\u1ec3 c\u00f3 h\u01b0\u1edbng x\u1eed tr\u00ed an to\u00e0n.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Trong b\u00e0i vi\u1ebft n\u00e0y,\u00a0nh\u00e0 thu\u1ed1c L\u01b0u V\u0103n Ho\u00e0ng\u00a0gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m\u00a0thu\u1ed1c\u00a0Imbruvica\u00a0\u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi c\u00f4ng ty Catalent Cts, llc &#8211; M\u1ef9, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN3-44-18, \u0111\u01b0\u1ee3c \u0111\u0103ng k\u00fd b\u1edfi c\u00f4ng ty Janssen-Cilag., ltd Imbruvica l\u00e0 thu\u1ed1c g\u00ec? Thu\u1ed1c Imbruvica\u00a0l\u00e0 thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb [&#8230;]\n","protected":false},"author":1,"featured_media":82167,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-13702","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/13702","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=13702"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/82167"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=13702"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=13702"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=13702"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}