{"id":136739,"date":"2025-09-04T23:32:10","date_gmt":"2025-09-04T16:32:10","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=136739"},"modified":"2025-12-23T12:44:29","modified_gmt":"2025-12-23T05:44:29","slug":"cotrimstada","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/cotrimstada\/","title":{"rendered":"Cotrimstada"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Cotrimstada \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean Doanh Stellapharm \u2013 Chi nh\u00e1nh 1, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-23965-15.<\/strong><\/p>\n<h2>Cotrimstada l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Cotrimstada<\/strong> l\u00e0 m\u1ed9t lo\u1ea1i kh\u00e1ng sinh ph\u1ed1i h\u1ee3p, m\u1ed7i vi\u00ean n\u00e9n ch\u1ee9a<strong> Sulfamethoxazole<\/strong> 400mg v\u00e0 Trimethoprim 80mg.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-23965-15<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 2 v\u1ec9 x 10 vi\u00ean, h\u1ed9p 10 v\u1ec9 x 10 vi\u00ean, h\u1ed9p 1 chai 100 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_136746\" aria-describedby=\"caption-attachment-136746\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-136746\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Cotrimstada.jpg\" alt=\"Cotrimstada d\u1ef1 ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Cotrimstada.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Cotrimstada-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Cotrimstada-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/09\/Cotrimstada-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-136746\" class=\"wp-caption-text\">Cotrimstada d\u1ef1 ph\u00f2ng v\u00e0 \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Cotrimstada<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a Cotrimoxazole l\u00e0 m\u1ed9t v\u00ed d\u1ee5 \u0111i\u1ec3n h\u00ecnh v\u1ec1 s\u1ef1 hi\u1ec7p \u0111\u1ed3ng t\u0103ng m\u1ee9c trong d\u01b0\u1ee3c l\u00fd h\u1ecdc kh\u00e1ng sinh. Thu\u1ed1c \u1ee9c ch\u1ebf hai b\u01b0\u1edbc li\u00ean ti\u1ebfp trong con \u0111\u01b0\u1eddng sinh t\u1ed5ng h\u1ee3p acid folic c\u1ee7a vi khu\u1ea9n, m\u1ed9t ch\u1ea5t thi\u1ebft y\u1ebfu cho qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p DNA, RNA v\u00e0 protein c\u1ee7a ch\u00fang.<\/p>\n<ul>\n<li>Sulfamethoxazole: L\u00e0 m\u1ed9t kh\u00e1ng sinh nh\u00f3m sulfonamid, c\u00f3 c\u1ea5u tr\u00fac t\u01b0\u01a1ng t\u1ef1 acid para-aminobenzoic (PABA) &#8211; ti\u1ec1n ch\u1ea5t c\u1ee7a acid folic \u1edf vi khu\u1ea9n. N\u00f3 c\u1ea1nh tranh v\u1edbi PABA \u0111\u1ec3 li\u00ean k\u1ebft v\u00e0o enzym Dihydropteroate synthase, qua \u0111\u00f3 ng\u0103n ch\u1eb7n qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p acid dihydrofolic.<\/li>\n<li>Trimethoprim: \u1ee8c ch\u1ebf m\u1ed9t c\u00e1ch ch\u1ecdn l\u1ecdc enzym Dihydrofolate reductase (DHFR) c\u1ee7a vi khu\u1ea9n. Enzym n\u00e0y x\u00fac t\u00e1c cho b\u01b0\u1edbc chuy\u1ec3n h\u00f3a cu\u1ed1i c\u00f9ng, bi\u1ebfn acid dihydrofolic th\u00e0nh acid tetrahydrofolic (d\u1ea1ng ho\u1ea1t \u0111\u1ed9ng c\u1ee7a acid folic).<\/li>\n<\/ul>\n<p>S\u1ef1 phong t\u1ecfa \u0111\u1ed3ng th\u1eddi hai b\u01b0\u1edbc li\u00ean ti\u1ebfp n\u00e0y kh\u00f4ng ch\u1ec9 ng\u0103n ch\u1eb7n hi\u1ec7u qu\u1ea3 vi\u1ec7c s\u1ea3n xu\u1ea5t acid folic m\u00e0 c\u00f2n t\u1ea1o ra t\u00e1c d\u1ee5ng di\u1ec7t khu\u1ea9n m\u1ea1nh m\u1ebd. C\u01a1 ch\u1ebf hi\u1ec7p \u0111\u1ed3ng n\u00e0y c\u0169ng gi\u00fap l\u00e0m ch\u1eadm \u0111\u00e1ng k\u1ec3 s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00e1c ch\u1ee7ng vi khu\u1ea9n kh\u00e1ng thu\u1ed1c.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: C\u1ea3 Sulfamethoxazole v\u00e0 Trimethoprim \u0111\u1ec1u \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh v\u00e0 t\u1ed1t qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a sau khi u\u1ed1ng. N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng th\u01b0\u1eddng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 1-4 gi\u1edd.<\/p>\n<p>Ph\u00e2n b\u1ed1: Thu\u1ed1c ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i v\u00e0o c\u00e1c m\u00f4 v\u00e0 d\u1ecbch trong c\u01a1 th\u1ec3, bao g\u1ed3m c\u1ea3 d\u1ecbch n\u00e3o t\u1ee7y, d\u1ecbch tai gi\u1eefa, tuy\u1ebfn ti\u1ec1n li\u1ec7t v\u00e0 s\u1eefa m\u1eb9. Thu\u1ed1c c\u0169ng \u0111i qua \u0111\u01b0\u1ee3c h\u00e0ng r\u00e0o nhau thai.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: C\u1ea3 hai ho\u1ea1t ch\u1ea5t \u0111\u1ec1u \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a t\u1ea1i gan.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Thu\u1ed1c \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua th\u1eadn d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i v\u00e0 d\u1ea1ng \u0111\u00e3 chuy\u1ec3n h\u00f3a. Th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a Sulfamethoxazole kho\u1ea3ng 10-13 gi\u1edd v\u00e0 c\u1ee7a Trimethoprim kho\u1ea3ng 8-11 gi\u1edd \u1edf ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng.<\/p>\n<h2>Thu\u1ed1c Cotrimstada \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Cotrimstada \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho c\u00e1c tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m khu\u1ea9n do c\u00e1c vi sinh v\u1eadt nh\u1ea1y c\u1ea3m, bao g\u1ed3m:<\/p>\n<ul>\n<li>Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u: \u0110i\u1ec1u tr\u1ecb vi\u00eam b\u00e0ng quang c\u1ea5p kh\u00f4ng bi\u1ebfn ch\u1ee9ng, vi\u00eam tuy\u1ebfn ti\u1ec1n li\u1ec7t nhi\u1ec5m khu\u1ea9n, v\u00e0 d\u1ef1 ph\u00f2ng nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u t\u00e1i ph\u00e1t.<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p: \u0110\u1eb7c bi\u1ec7t trong \u0111i\u1ec1u tr\u1ecb \u0111\u1ee3t c\u1ea5p c\u1ee7a vi\u00eam ph\u1ebf qu\u1ea3n m\u1ea1n \u1edf ng\u01b0\u1eddi l\u1edbn.<\/li>\n<li>Vi\u00eam tai gi\u1eefa c\u1ea5p: Th\u01b0\u1eddng \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u1edf tr\u1ebb em, \u0111\u1eb7c bi\u1ec7t do c\u00e1c ch\u1ee7ng <em>Haemophilus influenzae<\/em> ho\u1eb7c <em>Streptococcus pneumoniae<\/em>.<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u00eau h\u00f3a: \u0110i\u1ec1u tr\u1ecb l\u1ef5 tr\u1ef1c khu\u1ea9n do c\u00e1c ch\u1ee7ng <em>Shigella<\/em> nh\u1ea1y c\u1ea3m.<\/li>\n<li>Vi\u00eam ph\u1ed5i do <em>Pneumocystis jirovecii<\/em> (PJP): \u0110\u00e2y l\u00e0 m\u1ed9t ch\u1ec9 \u0111\u1ecbnh c\u1ef1c k\u1ef3 quan tr\u1ecdng. Cotrimoxazole l\u00e0 l\u1ef1a ch\u1ecdn h\u00e0ng \u0111\u1ea7u cho c\u1ea3 \u0111i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng PJP, m\u1ed9t lo\u1ea1i nhi\u1ec5m tr\u00f9ng c\u01a1 h\u1ed9i th\u01b0\u1eddng g\u1eb7p \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n suy gi\u1ea3m mi\u1ec5n d\u1ecbch (v\u00ed d\u1ee5: HIV\/AIDS, b\u1ec7nh nh\u00e2n gh\u00e9p t\u1ea1ng).<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Cotrimstada<\/h2>\n<p>Li\u1ec1u l\u01b0\u1ee3ng ph\u1ee5 thu\u1ed9c v\u00e0o lo\u1ea1i nhi\u1ec5m khu\u1ea9n, m\u1ee9c \u0111\u1ed9 n\u1eb7ng nh\u1eb9 v\u00e0 ch\u1ee9c n\u0103ng th\u1eadn c\u1ee7a b\u1ec7nh nh\u00e2n. Li\u1ec1u th\u00f4ng th\u01b0\u1eddng cho ng\u01b0\u1eddi l\u1edbn trong c\u00e1c nhi\u1ec5m khu\u1ea9n c\u1ea5p l\u00e0 2 vi\u00ean\/l\u1ea7n, 2 l\u1ea7n\/ng\u00e0y. B\u1ec7nh nh\u00e2n c\u1ea7n tu\u00e2n th\u1ee7 nghi\u00eam ng\u1eb7t li\u1ec1u l\u01b0\u1ee3ng do b\u00e1c s\u0129 ch\u1ec9 \u0111\u1ecbnh.<\/p>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Cotrimstada<\/h2>\n<p>Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng. \u0110\u1ec3 gi\u1ea3m thi\u1ec3u nguy c\u01a1 r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a, n\u00ean u\u1ed1ng thu\u1ed1c c\u00f9ng v\u1edbi b\u1eefa \u0103n. M\u1ed9t l\u01b0u \u00fd c\u1ef1c k\u1ef3 quan tr\u1ecdng l\u00e0 ph\u1ea3i <strong>u\u1ed1ng thu\u1ed1c v\u1edbi nhi\u1ec1u n\u01b0\u1edbc<\/strong> (\u00edt nh\u1ea5t m\u1ed9t c\u1ed1c \u0111\u1ea7y). \u0110i\u1ec1u n\u00e0y gi\u00fap \u0111\u1ea3m b\u1ea3o hydrat h\u00f3a \u0111\u1ea7y \u0111\u1ee7, l\u00e0m lo\u00e3ng n\u01b0\u1edbc ti\u1ec3u v\u00e0 gi\u1ea3m \u0111\u00e1ng k\u1ec3 nguy c\u01a1 h\u00ecnh th\u00e0nh tinh th\u1ec3 thu\u1ed1c trong \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u (tinh th\u1ec3 ni\u1ec7u), m\u1ed9t bi\u1ebfn ch\u1ee9ng ti\u1ec1m t\u00e0ng c\u1ee7a nh\u00f3m sulfonamid.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Cotrimstada trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>B\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn v\u1edbi Sulfamethoxazole, Trimethoprim ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>B\u1ec7nh nh\u00e2n suy gan n\u1eb7ng ho\u1eb7c t\u1ed5n th\u01b0\u01a1ng nhu m\u00f4 gan \u0111\u00e1ng k\u1ec3.<\/p>\n<p>Ch\u1ee9c n\u0103ng th\u1eadn suy gi\u1ea3m nghi\u00eam tr\u1ecdng, v\u1edbi m\u1ee9c l\u1ecdc c\u1ea7u th\u1eadn d\u01b0\u1edbi 15 ml\/ph\u00fat.<\/p>\n<p>T\u00ecnh tr\u1ea1ng thi\u1ebfu m\u00e1u nguy\u00ean h\u1ed3ng c\u1ea7u kh\u1ed5ng l\u1ed3 (megaloblastic anemia) g\u00e2y ra b\u1edfi s\u1ef1 thi\u1ebfu h\u1ee5t folate.<\/p>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai, ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa v\u00e0 tr\u1ebb s\u01a1 sinh d\u01b0\u1edbi 2 th\u00e1ng tu\u1ed5i.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Cotrimstada<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>R\u1ed1i lo\u1ea1n huy\u1ebft h\u1ecdc: Cotrimoxazole c\u00f3 th\u1ec3 g\u00e2y \u1ee9c ch\u1ebf t\u1ee7y x\u01b0\u01a1ng, d\u1eabn \u0111\u1ebfn thi\u1ebfu m\u00e1u, gi\u1ea3m b\u1ea1ch c\u1ea7u v\u00e0 gi\u1ea3m ti\u1ec3u c\u1ea7u. Nguy c\u01a1 n\u00e0y t\u0103ng l\u00ean \u1edf ng\u01b0\u1eddi cao tu\u1ed5i, ng\u01b0\u1eddi c\u00f3 t\u00ecnh tr\u1ea1ng thi\u1ebfu h\u1ee5t folate t\u1eeb tr\u01b0\u1edbc, ho\u1eb7c khi s\u1eed d\u1ee5ng thu\u1ed1c li\u1ec1u cao v\u00e0 k\u00e9o d\u00e0i. C\u1ea7n theo d\u00f5i c\u00f4ng th\u1ee9c m\u00e1u \u0111\u1ecbnh k\u1ef3 trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p n\u00e0y.<\/p>\n<p>T\u1ed5n th\u01b0\u01a1ng th\u1eadn: Nguy c\u01a1 tinh th\u1ec3 ni\u1ec7u, vi\u00eam th\u1eadn k\u1ebd v\u00e0 suy th\u1eadn c\u1ea5p c\u00f3 th\u1ec3 x\u1ea3y ra, \u0111\u1eb7c bi\u1ec7t n\u1ebfu b\u1ec7nh nh\u00e2n kh\u00f4ng u\u1ed1ng \u0111\u1ee7 n\u01b0\u1edbc. Ngo\u00e0i ra, thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y t\u0103ng kali m\u00e1u, \u0111\u1eb7c bi\u1ec7t nguy hi\u1ec3m \u1edf ng\u01b0\u1eddi cao tu\u1ed5i, b\u1ec7nh nh\u00e2n c\u00f3 b\u1ec7nh th\u1eadn n\u1ec1n ho\u1eb7c \u0111ang d\u00f9ng \u0111\u1ed3ng th\u1eddi c\u00e1c thu\u1ed1c kh\u00e1c c\u0169ng l\u00e0m t\u0103ng kali m\u00e1u.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p: R\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a (bu\u1ed3n n\u00f4n, n\u00f4n, ti\u00eau ch\u1ea3y), ph\u00e1t ban da.<\/p>\n<p>\u00cdt g\u1eb7p: M\u00e0y \u0111ay, ng\u1ee9a.<\/p>\n<p>Hi\u1ebfm g\u1eb7p: Ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7, SJS, TEN, v\u00e0ng da \u1ee9 m\u1eadt, ho\u1ea1i t\u1eed gan, suy t\u1ee7y, thi\u1ebfu m\u00e1u t\u00e1n huy\u1ebft (\u1edf ng\u01b0\u1eddi thi\u1ebfu G6PD), vi\u00eam th\u1eadn k\u1ebd, t\u0103ng kali m\u00e1u, h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Warfarin: Cotrimoxazole l\u00e0m t\u0103ng \u0111\u00e1ng k\u1ec3 t\u00e1c d\u1ee5ng ch\u1ed1ng \u0111\u00f4ng c\u1ee7a Warfarin, t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u. C\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd ch\u1ec9 s\u1ed1 INR.<\/p>\n<p>Methotrexate: T\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a Methotrexate do b\u1ecb \u0111\u1ea9y ra kh\u1ecfi li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng v\u00e0 gi\u1ea3m th\u1ea3i tr\u1eeb qua th\u1eadn.<\/p>\n<p>C\u00e1c thu\u1ed1c l\u00e0m t\u0103ng kali m\u00e1u: S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n (ACEi), ch\u1eb9n th\u1ee5 th\u1ec3 angiotensin (ARB), ho\u1eb7c l\u1ee3i ti\u1ec3u gi\u1eef kali c\u00f3 th\u1ec3 g\u00e2y t\u0103ng kali m\u00e1u n\u1eb7ng.<\/p>\n<p>Phenytoin, Digoxin: Cotrimoxazole c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 c\u1ee7a c\u00e1c thu\u1ed1c n\u00e0y trong m\u00e1u.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Cotrimoxazole ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh cho ph\u1ee5 n\u1eef c\u00f3 thai. Thu\u1ed1c can thi\u1ec7p v\u00e0o chuy\u1ec3n h\u00f3a acid folic, c\u00f3 th\u1ec3 g\u00e2y d\u1ecb t\u1eadt \u1ed1ng th\u1ea7n kinh cho thai nhi, \u0111\u1eb7c bi\u1ec7t trong 3 th\u00e1ng \u0111\u1ea7u. Trong 3 th\u00e1ng cu\u1ed1i, thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y v\u00e0ng da nh\u00e2n \u1edf tr\u1ebb s\u01a1 sinh. Thu\u1ed1c c\u0169ng b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9 v\u00e0 kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Hi\u1ebfm khi thu\u1ed1c g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 ch\u00f3ng m\u1eb7t, bu\u1ed3n ng\u1ee7. Tuy nhi\u00ean, n\u1ebfu g\u1eb7p ph\u1ea3i c\u00e1c tri\u1ec7u ch\u1ee9ng n\u00e0y, b\u1ec7nh nh\u00e2n kh\u00f4ng n\u00ean l\u00e1i xe hay v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tri\u1ec7u ch\u1ee9ng: Bu\u1ed3n n\u00f4n, n\u00f4n, ch\u00f3ng m\u1eb7t, l\u00fa l\u1eabn, v\u00e0 \u1ee9c ch\u1ebf t\u1ee7y x\u01b0\u01a1ng (trong tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u m\u1ea1n t\u00ednh).<\/p>\n<p>X\u1eed tr\u00ed: C\u1ea7n \u0111\u01b0a b\u1ec7nh nh\u00e2n \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf ngay l\u1eadp t\u1ee9c. C\u00e1c bi\u1ec7n ph\u00e1p x\u1eed tr\u00ed bao g\u1ed3m r\u1eeda d\u1ea1 d\u00e0y, hydrat h\u00f3a t\u00edch c\u1ef1c \u0111\u1ec3 t\u0103ng th\u1ea3i tr\u1eeb thu\u1ed1c qua n\u01b0\u1edbc ti\u1ec3u, v\u00e0 \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3. C\u00f3 th\u1ec3 d\u00f9ng Leucovorin (acid folinic) \u0111\u1ec3 \u0111\u1ed1i kh\u00e1ng t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf t\u1ee7y x\u01b0\u01a1ng c\u1ee7a Trimethoprim.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n thu\u1ed1c Cotrimstada \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t, nhi\u1ec7t \u0111\u1ed9 kh\u00f4ng qu\u00e1 30\u00b0C, tr\u00e1nh \u00e1nh s\u00e1ng tr\u1ef1c ti\u1ebfp v\u00e0 \u0111\u1ec3 xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Cotrimstada<\/h2>\n<p>Tr\u00ean th\u1ecb tr\u01b0\u1eddng c\u00f3 nhi\u1ec1u s\u1ea3n ph\u1ea9m ch\u1ee9a c\u00f9ng ho\u1ea1t ch\u1ea5t Cotrimstada. D\u01b0\u1edbi \u0111\u00e2y l\u00e0 th\u00f4ng tin v\u1ec1 m\u1ed9t s\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 l\u00e0 thu\u1ed1c<a href=\"https:\/\/vnras.com\/drug\/trimeseptol-400-80\/\"> Trimeseptol 400\/80<\/a> \u0111\u1ec3 tham kh\u1ea3o:<\/p>\n<ul>\n<li>Th\u00e0nh ph\u1ea7n: Sulfamethoxazole 400mg, Trimethoprim 80mg.<\/li>\n<li>S\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m H\u00e0 T\u00e2y.<\/li>\n<\/ul>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Maxwell J Lasko, Jennifer L Tabor-Rennie. Trimethoprim\/sulfamethoxazole pharmacodynamics against Stenotrophomonas maltophilia in the in vitro chemostat model, truy c\u1eadp ng\u00e0y 04 th\u00e1ng 09 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36101486\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/36101486\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>S\u1ea3n ph\u1ea9m thu\u1ed1c Cotrimstada \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean Doanh Stellapharm \u2013 Chi nh\u00e1nh 1, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-23965-15, \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n do c\u00e1c vi sinh v\u1eadt nh\u1ea1y c\u1ea3m.<\/p>\n","protected":false},"author":1,"featured_media":136745,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-136739","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/136739","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=136739"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/136745"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=136739"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=136739"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=136739"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}