{"id":135660,"date":"2025-08-28T09:38:43","date_gmt":"2025-08-28T02:38:43","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=135660"},"modified":"2025-08-28T09:39:47","modified_gmt":"2025-08-28T02:39:47","slug":"statinagi-20","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/statinagi-20\/","title":{"rendered":"Statinagi 20"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Statinagi 20 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Chi nh\u00e1nh c\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Agimexpharm- Nh\u00e0 m\u00e1y s\u1ea3n xu\u1ea5t d\u01b0\u1ee3c ph\u1ea9m Agimexpharm, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110381424 (VD-23490-15).<\/strong><\/p>\n<h2>Statinagi 20 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Statinagi 20<\/strong> l\u00e0 m\u1ed9t thu\u1ed1c k\u00ea \u0111\u01a1n thu\u1ed9c nh\u00f3m statin, c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t: <strong>Atorvastatin <\/strong>(d\u01b0\u1edbi d\u1ea1ng Atorvastatin calci) h\u00e0m l\u01b0\u1ee3ng 20 mg.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: Lactose monohydrat, Croscarmellose natri, Microcrystallin cellulose 112, v\u00e0 c\u00e1c t\u00e1 d\u01b0\u1ee3c kh\u00e1c v\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110381424 (VD-23490-15)<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9, 6 v\u1ec9, 10 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_135661\" aria-describedby=\"caption-attachment-135661\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-135661\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Statinagi-20.jpg\" alt=\"Statinagi 20 d\u1ef1 ph\u00f2ng bi\u1ebfn c\u1ed1 tim m\u1ea1ch do x\u01a1 v\u1eefa\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Statinagi-20.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Statinagi-20-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Statinagi-20-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Statinagi-20-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-135661\" class=\"wp-caption-text\">Statinagi 20 d\u1ef1 ph\u00f2ng bi\u1ebfn c\u1ed1 tim m\u1ea1ch do x\u01a1 v\u1eefa<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Statinagi 20<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Atorvastatin ph\u00e1t huy t\u00e1c d\u1ee5ng th\u00f4ng qua c\u01a1 ch\u1ebf \u1ee9c ch\u1ebf c\u1ea1nh tranh v\u00e0 ch\u1ecdn l\u1ecdc enzym HMG-CoA reductase. \u0110\u00e2y l\u00e0 enzym ch\u1ee7 ch\u1ed1t, quy\u1ebft \u0111\u1ecbnh t\u1ed1c \u0111\u1ed9 c\u1ee7a con \u0111\u01b0\u1eddng sinh t\u1ed5ng h\u1ee3p cholesterol n\u1ed9i sinh t\u1ea1i gan. B\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf enzym n\u00e0y, Atorvastatin l\u00e0m gi\u1ea3m s\u1ea3n xu\u1ea5t cholesterol \u1edf gan.<\/p>\n<p>S\u1ef1 s\u1ee5t gi\u1ea3m n\u1ed3ng \u0111\u1ed9 cholesterol n\u1ed9i b\u00e0o k\u00edch ho\u1ea1t m\u1ed9t c\u01a1 ch\u1ebf b\u00f9 tr\u1eeb: c\u00e1c t\u1ebf b\u00e0o gan t\u0103ng c\u01b0\u1eddng bi\u1ec3u hi\u1ec7n c\u00e1c th\u1ee5 th\u1ec3 LDL (LDL receptor) tr\u00ean b\u1ec1 m\u1eb7t. Vi\u1ec7c gia t\u0103ng s\u1ed1 l\u01b0\u1ee3ng th\u1ee5 th\u1ec3 n\u00e0y l\u00e0m t\u0103ng c\u01b0\u1eddng \u0111\u1ed9 thanh th\u1ea3i LDL-cholesterol ra kh\u1ecfi tu\u1ea7n ho\u00e0n, t\u1eeb \u0111\u00f3 l\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 n\u1ed3ng \u0111\u1ed9 LDL-C, cholesterol to\u00e0n ph\u1ea7n v\u00e0 apolipoprotein B trong huy\u1ebft t\u01b0\u01a1ng. Ngo\u00e0i ra, Atorvastatin c\u0169ng c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m gi\u1ea3m VLDL-C v\u00e0 triglycerid, \u0111\u1ed3ng th\u1eddi l\u00e0m t\u0103ng nh\u1eb9 HDL-C (cholesterol &#8220;t\u1ed1t&#8221;).<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Atorvastatin \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh ch\u00f3ng sau khi u\u1ed1ng, \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau 1-2 gi\u1edd.<\/p>\n<p>Ph\u00e2n b\u1ed1: Thu\u1ed1c li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (\u2265 98%).<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Atorvastatin \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu t\u1ea1i gan b\u1edfi h\u1ec7 enzym cytochrom P450 3A4 (CYP3A4), t\u1ea1o ra c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a v\u1eabn c\u00f2n ho\u1ea1t t\u00ednh.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Thu\u1ed1c v\u00e0 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a n\u00f3 \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb ch\u00ednh qua m\u1eadt. Th\u1eddi gian b\u00e1n th\u1ea3i trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a Atorvastatin kho\u1ea3ng 14 gi\u1edd, nh\u01b0ng ho\u1ea1t t\u00ednh \u1ee9c ch\u1ebf HMG-CoA reductase k\u00e9o d\u00e0i t\u1edbi 20-30 gi\u1edd do s\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh.<\/p>\n<h2>Thu\u1ed1c Statinagi 20 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Statinagi 20 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh nh\u01b0 m\u1ed9t li\u1ec7u ph\u00e1p h\u1ed7 tr\u1ee3 cho ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n<ul>\n<li>T\u0103ng cholesterol m\u00e1u v\u00e0 R\u1ed1i lo\u1ea1n lipid m\u00e1u h\u1ed7n h\u1ee3p: Gi\u1ea3m m\u1ee9c cholesterol to\u00e0n ph\u1ea7n, LDL-C, apolipoprotein B v\u00e0 triglycerid \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 10 tu\u1ed5i tr\u1edf l\u00ean b\u1ecb t\u0103ng cholesterol m\u00e1u nguy\u00ean ph\u00e1t (bao g\u1ed3m c\u1ea3 t\u0103ng cholesterol m\u00e1u gia \u0111\u00ecnh ki\u1ec3u d\u1ecb h\u1ee3p t\u1eed) ho\u1eb7c r\u1ed1i lo\u1ea1n lipid m\u00e1u h\u1ed7n h\u1ee3p.<\/li>\n<li>T\u0103ng cholesterol m\u00e1u gia \u0111\u00ecnh ki\u1ec3u \u0111\u1ed3ng h\u1ee3p t\u1eed: Gi\u1ea3m LDL-C v\u00e0 cholesterol to\u00e0n ph\u1ea7n \u1edf ng\u01b0\u1eddi l\u1edbn, th\u01b0\u1eddng k\u1ebft h\u1ee3p v\u1edbi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb h\u1ea1 lipid kh\u00e1c.<\/li>\n<li>D\u1ef1 ph\u00f2ng c\u00e1c bi\u1ebfn c\u1ed1 tim m\u1ea1ch do x\u01a1 v\u1eefa:\n<ul>\n<li>D\u1ef1 ph\u00f2ng ti\u00ean ph\u00e1t: \u1ede nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 cao b\u1ecb bi\u1ebfn c\u1ed1 tim m\u1ea1ch l\u1ea7n \u0111\u1ea7u (v\u00ed d\u1ee5: b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, t\u0103ng huy\u1ebft \u00e1p c\u00f3 k\u00e8m theo c\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 kh\u00e1c).<\/li>\n<li>D\u1ef1 ph\u00f2ng th\u1ee9 ph\u00e1t: \u1ede nh\u1eefng b\u1ec7nh nh\u00e2n \u0111\u00e3 c\u00f3 ti\u1ec1n s\u1eed b\u1ec7nh tim m\u1ea1ch do x\u01a1 v\u1eefa (v\u00ed d\u1ee5: nh\u1ed3i m\u00e1u c\u01a1 tim, \u0111\u1ed9t qu\u1ef5, b\u1ec7nh \u0111\u1ed9ng m\u1ea1ch v\u00e0nh) \u0111\u1ec3 l\u00e0m gi\u1ea3m nguy c\u01a1 t\u00e1i ph\u00e1t.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Statinagi 20<\/h2>\n<p>Li\u1ec1u kh\u1edfi \u0111\u1ea7u th\u00f4ng th\u01b0\u1eddng l\u00e0 10 mg\/ng\u00e0y.<\/p>\n<p>Ph\u1ea1m vi li\u1ec1u \u0111i\u1ec1u tr\u1ecb l\u00e0 t\u1eeb 10-80 mg\/ng\u00e0y. Li\u1ec1u d\u00f9ng ph\u1ea3i \u0111\u01b0\u1ee3c c\u00e1 nh\u00e2n h\u00f3a d\u1ef1a tr\u00ean n\u1ed3ng \u0111\u1ed9 LDL-C ban \u0111\u1ea7u, m\u1ee5c ti\u00eau \u0111i\u1ec1u tr\u1ecb v\u00e0 \u0111\u00e1p \u1ee9ng c\u1ee7a t\u1eebng b\u1ec7nh nh\u00e2n.<\/p>\n<p>B\u00e1c s\u0129 c\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u sau m\u1ed7i 4 tu\u1ea7n ho\u1eb7c h\u01a1n n\u1ebfu c\u1ea7n thi\u1ebft. B\u1ec7nh nh\u00e2n c\u1ea7n tu\u00e2n th\u1ee7 nghi\u00eam ng\u1eb7t ch\u1ec9 \u0111\u1ecbnh v\u1ec1 li\u1ec1u l\u01b0\u1ee3ng c\u1ee7a b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Statinagi 20<\/h2>\n<p>Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng, m\u1ed9t l\u1ea7n duy nh\u1ea5t trong ng\u00e0y, c\u00f3 th\u1ec3 u\u1ed1ng v\u00e0o b\u1ea5t k\u1ef3 th\u1eddi \u0111i\u1ec3m n\u00e0o, kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o b\u1eefa \u0103n.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Statinagi 20 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>B\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn v\u1edbi Atorvastatin ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>B\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh gan \u0111ang ti\u1ebfn tri\u1ec3n ho\u1eb7c c\u00f3 t\u00ecnh tr\u1ea1ng t\u0103ng men gan (transaminase) dai d\u1eb3ng kh\u00f4ng r\u00f5 nguy\u00ean nh\u00e2n, v\u01b0\u1ee3t qu\u00e1 3 l\u1ea7n gi\u1edbi h\u1ea1n tr\u00ean c\u1ee7a m\u1ee9c b\u00ecnh th\u01b0\u1eddng.<\/p>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai, ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa, ho\u1eb7c ph\u1ee5 n\u1eef trong \u0111\u1ed9 tu\u1ed5i sinh \u0111\u1ebb m\u00e0 kh\u00f4ng s\u1eed d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p tr\u00e1nh thai hi\u1ec7u qu\u1ea3.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Statinagi 20<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Nguy c\u01a1 g\u00e2y \u0111\u1ed9c t\u00ednh tr\u00ean c\u01a1 (Myopathy):<\/p>\n<ul>\n<li>Atorvastatin, c\u0169ng nh\u01b0 c\u00e1c statin kh\u00e1c, c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c b\u1ec7nh l\u00fd v\u1ec1 c\u01a1. Bi\u1ec3u hi\u1ec7n c\u00f3 th\u1ec3 t\u1eeb \u0111au c\u01a1, vi\u00eam c\u01a1 (myositis) cho \u0111\u1ebfn m\u1ed9t t\u00ecnh tr\u1ea1ng hi\u1ebfm g\u1eb7p nh\u01b0ng r\u1ea5t nghi\u00eam tr\u1ecdng l\u00e0 ti\u00eau c\u01a1 v\u00e2n (rhabdomyolysis).<\/li>\n<li>Ti\u00eau c\u01a1 v\u00e2n l\u00e0 t\u00ecnh tr\u1ea1ng c\u00e1c t\u1ebf b\u00e0o c\u01a1 b\u1ecb ph\u00e1 h\u1ee7y h\u00e0ng lo\u1ea1t, gi\u1ea3i ph\u00f3ng myoglobin v\u00e0o m\u00e1u, c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn suy th\u1eadn c\u1ea5p v\u00e0 t\u1eed vong.<\/li>\n<li>B\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c h\u01b0\u1edbng d\u1eabn b\u00e1o ngay cho b\u00e1c s\u0129 n\u1ebfu xu\u1ea5t hi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 \u0111au c\u01a1 kh\u00f4ng gi\u1ea3i th\u00edch \u0111\u01b0\u1ee3c, y\u1ebfu c\u01a1, chu\u1ed9t r\u00fat, \u0111\u1eb7c bi\u1ec7t khi \u0111i k\u00e8m v\u1edbi s\u1ed1t ho\u1eb7c m\u1ec7t m\u1ecfi. B\u00e1c s\u0129 c\u00f3 th\u1ec3 y\u00eau c\u1ea7u x\u00e9t nghi\u1ec7m n\u1ed3ng \u0111\u1ed9 creatin kinase (CK) trong m\u00e1u \u0111\u1ec3 \u0111\u00e1nh gi\u00e1.<\/li>\n<li>Nguy c\u01a1 n\u00e0y t\u0103ng l\u00ean \u1edf ng\u01b0\u1eddi cao tu\u1ed5i, ng\u01b0\u1eddi suy th\u1eadn, suy gi\u00e1p, v\u00e0 khi d\u00f9ng li\u1ec1u cao ho\u1eb7c d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi m\u1ed9t s\u1ed1 thu\u1ed1c kh\u00e1c.<\/li>\n<\/ul>\n<p>\u1ea2nh h\u01b0\u1edfng tr\u00ean ch\u1ee9c n\u0103ng gan:<\/p>\n<ul>\n<li>Statin c\u00f3 th\u1ec3 g\u00e2y t\u0103ng men gan. Do \u0111\u00f3, b\u00e1c s\u0129 s\u1ebd ch\u1ec9 \u0111\u1ecbnh x\u00e9t nghi\u1ec7m ch\u1ee9c n\u0103ng gan (\u0111o n\u1ed3ng \u0111\u1ed9 ALT, AST) tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u00e0 \u0111\u1ecbnh k\u1ef3 trong qu\u00e1 tr\u00ecnh s\u1eed d\u1ee5ng thu\u1ed1c.<\/li>\n<li>N\u1ebfu men gan t\u0103ng cao h\u01a1n 3 l\u1ea7n gi\u1edbi h\u1ea1n tr\u00ean c\u1ee7a m\u1ee9c b\u00ecnh th\u01b0\u1eddng v\u00e0 k\u00e9o d\u00e0i, vi\u1ec7c gi\u1ea3m li\u1ec1u ho\u1eb7c ng\u01b0ng thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p: Vi\u00eam m\u0169i h\u1ecdng, \u0111au \u0111\u1ea7u, ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng, t\u0103ng \u0111\u01b0\u1eddng huy\u1ebft, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a (t\u00e1o b\u00f3n, \u0111\u1ea7y h\u01a1i, bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y), \u0111au c\u01a1, \u0111au kh\u1edbp, \u0111au l\u01b0ng.<\/p>\n<p>\u00cdt g\u1eb7p: H\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, t\u0103ng c\u00e2n, m\u1ea5t ng\u1ee7, \u00e1c m\u1ed9ng, ch\u00f3ng m\u1eb7t, nh\u00ecn m\u1edd, \u00f9 tai, vi\u00eam t\u1ee5y, vi\u00eam gan, ph\u00e1t ban da, ng\u1ee9a, m\u1ec7t m\u1ecfi.<\/p>\n<p>Hi\u1ebfm g\u1eb7p: Gi\u1ea3m ti\u1ec3u c\u1ea7u, b\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean, \u1ee9 m\u1eadt, c\u00e1c b\u1ec7nh l\u00fd v\u1ec1 c\u01a1 (vi\u00eam c\u01a1, ti\u00eau c\u01a1 v\u00e2n).<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Nguy c\u01a1 \u0111\u1ed9c t\u00ednh tr\u00ean c\u01a1 t\u0103ng l\u00ean \u0111\u00e1ng k\u1ec3 khi d\u00f9ng Statinagi 20 chung v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf m\u1ea1nh enzym gan CYP3A4. C\u00e1c t\u01b0\u01a1ng t\u00e1c quan tr\u1ecdng c\u1ea7n l\u01b0u \u00fd bao g\u1ed3m:<\/p>\n<ul>\n<li>Kh\u00e1ng sinh nh\u00f3m Macrolid: Clarithromycin, Erythromycin.<\/li>\n<li>Thu\u1ed1c kh\u00e1ng n\u1ea5m nh\u00f3m Azol: Itraconazole, Ketoconazole.<\/li>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf Protease \u0111i\u1ec1u tr\u1ecb HIV\/HCV: Ritonavir, Lopinavir.<\/li>\n<li>M\u1ed9t s\u1ed1 thu\u1ed1c tim m\u1ea1ch kh\u00e1c: Ciclosporin.<\/li>\n<li>N\u01b0\u1edbc \u00e9p b\u01b0\u1edfi: Ti\u00eau th\u1ee5 l\u01b0\u1ee3ng l\u1edbn n\u01b0\u1edbc \u00e9p b\u01b0\u1edfi c\u0169ng c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Atorvastatin trong m\u00e1u.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh tuy\u1ec7t \u0111\u1ed1i. Cholesterol l\u00e0 m\u1ed9t ch\u1ea5t c\u1ef1c k\u1ef3 quan tr\u1ecdng cho s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a thai nhi. Vi\u1ec7c s\u1eed d\u1ee5ng statin trong thai k\u1ef3 c\u00f3 th\u1ec3 g\u00e2y h\u1ea1i nghi\u00eam tr\u1ecdng. Ph\u1ee5 n\u1eef d\u00f9ng Statinagi 20 kh\u00f4ng \u0111\u01b0\u1ee3c cho con b\u00fa do thu\u1ed1c c\u00f3 th\u1ec3 b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 \u1ea3nh h\u01b0\u1edfng kh\u00f4ng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c, tuy nhi\u00ean, n\u1ebfu g\u1eb7p t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 ch\u00f3ng m\u1eb7t, c\u1ea7n th\u1eadn tr\u1ecdng.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Kh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u. Trong tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u, c\u1ea7n \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 \u00e1p d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 c\u1ea7n thi\u1ebft. Theo d\u00f5i ch\u1eb7t ch\u1ebd ch\u1ee9c n\u0103ng gan v\u00e0 n\u1ed3ng \u0111\u1ed9 CK huy\u1ebft thanh.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n thu\u1ed1c Statinagi 20 \u1edf n\u01a1i kh\u00f4 r\u00e1o, nhi\u1ec7t \u0111\u1ed9 kh\u00f4ng qu\u00e1 30\u00b0C, tr\u00e1nh \u00e1nh s\u00e1ng tr\u1ef1c ti\u1ebfp v\u00e0 \u0111\u1ec3 xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Statinagi 20<\/h2>\n<p>Tr\u00ean th\u1ecb tr\u01b0\u1eddng c\u00f3 nhi\u1ec1u s\u1ea3n ph\u1ea9m ch\u1ee9a ho\u1ea1t ch\u1ea5t Atorvastatin 20mg. M\u1ed9t trong s\u1ed1 \u0111\u00f3 l\u00e0 thu\u1ed1c<a href=\"https:\/\/vnras.com\/drug\/atorvastatin-20-khapharco\/\"> Atorvastatin 20 Khapharco<\/a> s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Kh\u00e1nh H\u00f2a, c\u0169ng l\u00e0 m\u1ed9t l\u1ef1a ch\u1ecdn thay th\u1ebf v\u1edbi c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 h\u00e0m l\u01b0\u1ee3ng, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n lipid m\u00e1u v\u00e0 d\u1ef1 ph\u00f2ng bi\u1ebfn c\u1ed1 tim m\u1ea1ch.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Nan Hu, Chunyun Chen. Atorvastatin Ester Regulates Lipid Metabolism in Hyperlipidemia Rats via the PPAR-signaling Pathway and HMGCR Expression in the Liver, truy c\u1eadp ng\u00e0y 28 th\u00e1ng 09 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34681767\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34681767\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>S\u1ea3n ph\u1ea9m thu\u1ed1c Statinagi 20 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Chi nh\u00e1nh c\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Agimexpharm- Nh\u00e0 m\u00e1y s\u1ea3n xu\u1ea5t d\u01b0\u1ee3c ph\u1ea9m Agimexpharm, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110381424 (VD-23490-15).<\/p>\n","protected":false},"author":1,"featured_media":135662,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-135660","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/135660","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=135660"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/135662"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=135660"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=135660"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=135660"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}