{"id":135538,"date":"2025-08-28T13:27:15","date_gmt":"2025-08-28T06:27:15","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=135538"},"modified":"2025-08-29T16:38:51","modified_gmt":"2025-08-29T09:38:51","slug":"rosuvastatin-savi-10","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/rosuvastatin-savi-10\/","title":{"rendered":"Rosuvastatin Savi 10"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Rosuvastatin Savi 10 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Savi (Savipharm J.S.C) c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110030200 (S\u0110K c\u0169: VD-29117-18)<\/strong><\/p>\n

Rosuvastatin Savi 10 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n

Th\u00e0nh ph\u1ea7n<\/h3>\n

Trong m\u1ed7i vi\u00ean u\u1ed1ng Rosuvastatin Savi 10<\/strong> c\u00f3 ch\u1ee9a ho\u1ea1t ch\u1ea5t ch\u00ednh Rosuvastatin v\u1edbi h\u00e0m l\u01b0\u1ee3ng l\u00e0 10mg<\/p>\n

D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n

Tr\u00ecnh b\u00e0y<\/h3>\n

S\u0110K: 893110030200 (S\u0110K c\u0169: VD-29117-18)<\/p>\n

Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n

Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n

H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n

T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Rosuvastatin Savi 10<\/h2>\n

C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n

Rosuvastatin l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf c\u1ea1nh tranh v\u00e0 ch\u1ecdn l\u1ecdc enzym HMG-CoA reductase \u2013 enzym x\u00fac t\u00e1c qu\u00e1 tr\u00ecnh chuy\u1ec3n HMG-CoA th\u00e0nh mevalonat, ti\u1ec1n ch\u1ea5t quan tr\u1ecdng trong t\u1ed5ng h\u1ee3p cholesterol. T\u00e1c \u0111\u1ed9ng ch\u1ee7 y\u1ebfu di\u1ec5n ra t\u1ea1i gan \u2013 c\u01a1 quan ch\u00ednh chuy\u1ec3n h\u00f3a lipid.<\/p>\n

Ho\u1ea1t ch\u1ea5t n\u00e0y l\u00e0m t\u0103ng s\u1ed1 l\u01b0\u1ee3ng th\u1ee5 th\u1ec3 LDL tr\u00ean m\u00e0ng t\u1ebf b\u00e0o gan, t\u1eeb \u0111\u00f3 th\u00fac \u0111\u1ea9y thu b\u1eaft v\u00e0 ph\u00e2n h\u1ee7y LDL, \u0111\u1ed3ng th\u1eddi h\u1ea1n ch\u1ebf s\u1ef1 h\u00ecnh th\u00e0nh VLDL. Nh\u1edd v\u1eady, n\u1ed3ng \u0111\u1ed9 LDL-C v\u00e0 VLDL-C trong m\u00e1u \u0111\u01b0\u1ee3c h\u1ea1 th\u1ea5p r\u00f5 r\u1ec7t.<\/p>\n

\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n

H\u1ea5p thu: N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t kho\u1ea3ng sau 5 gi\u1edd u\u1ed1ng, sinh kh\u1ea3 d\u1ee5ng kho\u1ea3ng 20%.<\/p>\n

Ph\u00e2n b\u1ed1: T\u1eadp trung nhi\u1ec1u \u1edf gan, th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 kho\u1ea3ng 134 l\u00edt; g\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 90%, ch\u1ee7 y\u1ebfu v\u1edbi albumin.<\/p>\n

Chuy\u1ec3n h\u00f3a: \u00cdt b\u1ecb chuy\u1ec3n h\u00f3a (ch\u1ec9 kho\u1ea3ng 10%). Ch\u1ee7 y\u1ebfu b\u1edfi CYP2C9, ngo\u00e0i ra c\u00f2n c\u00f3 CYP2C19, CYP3A4 v\u00e0 CYP2D6 tham gia m\u1ed9t ph\u1ea7n nh\u1ecf. C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh l\u00e0 N-desmethyl (c\u00f3 ho\u1ea1t t\u00ednh y\u1ebfu h\u01a1n 50%) v\u00e0 d\u1ea1ng lacton (kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh l\u00e2m s\u00e0ng). H\u01a1n 90% t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf men HMG-CoA reductase trong tu\u1ea7n ho\u00e0n l\u00e0 do thu\u1ed1c g\u1ed1c.<\/p>\n

Th\u1ea3i tr\u1eeb: Kho\u1ea3ng 90% li\u1ec1u u\u1ed1ng th\u1ea3i qua ph\u00e2n d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i, 5% b\u00e0i ti\u1ebft qua n\u01b0\u1edbc ti\u1ec3u. Th\u1eddi gian b\u00e1n th\u1ea3i trung b\u00ecnh kho\u1ea3ng 19 gi\u1edd, \u0111\u1ed9 thanh th\u1ea3i huy\u1ebft t\u01b0\u01a1ng trung b\u00ecnh kho\u1ea3ng 50 l\u00edt\/gi\u1edd. S\u1ef1 v\u1eadn chuy\u1ec3n qua gan ph\u1ee5 thu\u1ed9c v\u00e0o ch\u1ea5t v\u1eadn chuy\u1ec3n OATP-C.<\/p>\n

Thu\u1ed1c Rosuvastatin Savi 10 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n

T\u0103ng cholesterol m\u00e1u nguy\u00ean ph\u00e1t (type IIa, bao g\u1ed3m t\u0103ng cholesterol gia \u0111\u00ecnh d\u1ecb h\u1ee3p t\u1eed) v\u00e0 r\u1ed1i lo\u1ea1n lipid h\u1ed7n h\u1ee3p (type IIb) \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em \u2265 6 tu\u1ed5i, khi ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang v\u00e0 c\u00e1c bi\u1ec7n ph\u00e1p kh\u00f4ng d\u00f9ng thu\u1ed1c kh\u00e1c ch\u01b0a ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c.<\/p>\n

T\u0103ng cholesterol m\u00e1u gia \u0111\u00ecnh \u0111\u1ed3ng h\u1ee3p t\u1eed, ph\u1ed1i h\u1ee3p v\u1edbi ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang v\u00e0 c\u00e1c bi\u1ec7n ph\u00e1p gi\u1ea3m lipid kh\u00e1c (nh\u01b0 l\u1ecdc LDL), ho\u1eb7c khi nh\u1eefng bi\u1ec7n ph\u00e1p n\u00e0y kh\u00f4ng ph\u00f9 h\u1ee3p.<\/p>\n

D\u1ef1 ph\u00f2ng bi\u1ebfn c\u1ed1 tim m\u1ea1ch \u1edf ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 cao.<\/p>\n

\"Rosuvastatin
Thu\u1ed1c Rosuvastatin Savi 10 c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb t\u0103ng cholesterol m\u00e1u<\/figcaption><\/figure>\n

Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n

Li\u1ec1u d\u00f9ng<\/h3>\n

Ng\u01b0\u1eddi l\u1edbn<\/strong><\/em><\/p>\n

Li\u1ec1u kh\u1edfi \u0111\u1ea7u: 5\u201310 mg\/l\u1ea7n\/ng\u00e0y.<\/p>\n

C\u00f3 th\u1ec3 t\u0103ng li\u1ec1u sau m\u1ed7i \u2265 4 tu\u1ea7n t\u00f9y \u0111\u00e1p \u1ee9ng.<\/p>\n

Li\u1ec1u t\u1ed1i \u0111a: 40 mg\/ng\u00e0y, ch\u1ec9 d\u00f9ng khi b\u1ec7nh nh\u00e2n nguy c\u01a1 tim m\u1ea1ch cao, kh\u00f4ng \u0111\u1ea1t m\u1ee5c ti\u00eau v\u1edbi li\u1ec1u 20 mg.<\/p>\n

Ph\u00f2ng ng\u1eeba bi\u1ebfn c\u1ed1 tim m\u1ea1ch: 20 mg\/ng\u00e0y.<\/p>\n

Tr\u1ebb em 6\u201317 tu\u1ed5i<\/strong><\/em><\/p>\n

6\u20139 tu\u1ed5i: 5\u201310 mg\/ng\u00e0y.<\/p>\n

10\u201317 tu\u1ed5i: 5\u201320 mg\/ng\u00e0y.<\/p>\n

Ng\u01b0\u1eddi cao tu\u1ed5i: Kh\u00f4ng c\u1ea7n ch\u1ec9nh li\u1ec1u.<\/p>\n

Suy th\u1eadn<\/strong><\/em><\/p>\n

Nh\u1eb9 \u2013 v\u1eeba: kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh.<\/p>\n

N\u1eb7ng (Clcr < 30 ml\/ph\u00fat): ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh.<\/p>\n

Suy gan<\/strong><\/em><\/p>\n

Child-Pugh \u2264 7: kh\u00f4ng c\u1ea7n ch\u1ec9nh li\u1ec1u.<\/p>\n

Child-Pugh 8\u20139: t\u0103ng ph\u01a1i nhi\u1ec5m, c\u1ea7n th\u1eadn tr\u1ecdng.<\/p>\n

Child-Pugh > 9 ho\u1eb7c b\u1ec7nh gan ti\u1ebfn tri\u1ec3n: ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh.<\/p>\n

Ng\u01b0\u1eddi ch\u00e2u \u00c1: N\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00e1u t\u0103ng g\u1ea5p \u0111\u00f4i so v\u1edbi ng\u01b0\u1eddi da tr\u1eafng, do \u0111\u00f3 li\u1ec1u kh\u1edfi \u0111\u1ea7u n\u00ean t\u1eeb 5 mg; ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng li\u1ec1u 40 mg.<\/p>\n

Khi ph\u1ed1i h\u1ee3p v\u1edbi thu\u1ed1c \u1ee9c ch\u1ebf protease (HIV, HCV): kh\u00f4ng v\u01b0\u1ee3t qu\u00e1 10 mg\/ng\u00e0y.<\/p>\n

C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n

U\u1ed1ng vi\u00ean n\u00e9n Rosuvastatin Savi 10<\/strong> tr\u1ef1c ti\u1ebfp, c\u00f3 th\u1ec3 d\u00f9ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng b\u1eefa \u0103n.<\/p>\n

B\u1ec7nh nh\u00e2n c\u1ea7n duy tr\u00ec ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang gi\u1ea3m cholesterol tr\u01b0\u1edbc v\u00e0 trong su\u1ed1t th\u1eddi gian \u0111i\u1ec1u tr\u1ecb.<\/p>\n

Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Rosuvastatin Savi 10 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n

Ng\u01b0\u1eddi m\u1eabn c\u1ea3m v\u1edbi rosuvastatin ho\u1eb7c b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n

B\u1ec7nh gan ti\u1ebfn tri\u1ec3n, t\u0103ng men gan k\u00e9o d\u00e0i ho\u1eb7c kh\u00f4ng r\u00f5 nguy\u00ean nh\u00e2n; men gan > 3 l\u1ea7n gi\u1edbi h\u1ea1n tr\u00ean b\u00ecnh th\u01b0\u1eddng.<\/p>\n

Suy th\u1eadn n\u1eb7ng (Clcr < 30 ml\/ph\u00fat).<\/p>\n

B\u1ec7nh l\u00fd v\u1ec1 c\u01a1.<\/p>\n

\u0110ang d\u00f9ng cyclosporin.<\/p>\n

Ph\u1ee5 n\u1eef c\u00f3 thai, \u0111ang cho con b\u00fa ho\u1eb7c ph\u1ee5 n\u1eef c\u00f3 kh\u1ea3 n\u0103ng mang thai m\u00e0 kh\u00f4ng s\u1eed d\u1ee5ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai.<\/p>\n

Li\u1ec1u 40 mg ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf: ng\u01b0\u1eddi ch\u00e2u \u00c1, b\u1ec7nh nh\u00e2n suy th\u1eadn trung b\u00ecnh, suy gi\u00e1p, nghi\u1ec7n r\u01b0\u1ee3u, ti\u1ec1n s\u1eed b\u1ec7nh c\u01a1 ho\u1eb7c c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1 t\u1ed5n th\u01b0\u01a1ng c\u01a1, \u0111ang d\u00f9ng fibrat.<\/p>\n

L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n

Th\u1eadn tr\u1ecdng<\/h3>\n

C\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n protein ni\u1ec7u tho\u00e1ng qua khi d\u00f9ng li\u1ec1u cao (\u0111\u1eb7c bi\u1ec7t 40 mg). C\u1ea7n theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn \u0111\u1ecbnh k\u1ef3.<\/p>\n

Nguy c\u01a1 \u0111au c\u01a1, vi\u00eam c\u01a1, b\u1ec7nh c\u01a1, ti\u00eau c\u01a1 v\u00e2n, nh\u1ea5t l\u00e0 khi d\u00f9ng li\u1ec1u cao ho\u1eb7c ph\u1ed1i h\u1ee3p fibrat, niacin li\u1ec1u cao, colchicin, thu\u1ed1c \u0111i\u1ec1u tr\u1ecb HIV\/HCV. N\u00ean x\u00e9t nghi\u1ec7m CK tr\u01b0\u1edbc \u0111i\u1ec1u tr\u1ecb \u1edf b\u1ec7nh nh\u00e2n c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1. N\u1ebfu CK > 5 l\u1ea7n ULN, kh\u00f4ng b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb.<\/p>\n

C\u1ea7n ki\u1ec3m tra men gan tr\u01b0\u1edbc khi \u0111i\u1ec1u tr\u1ecb Rosuvastatin Savi 10, n\u00ean ng\u1eebng ho\u1eb7c gi\u1ea3m li\u1ec1u n\u1ebfu transaminase t\u0103ng > 3.ULN.<\/p>\n

\u0110\u1ed1i t\u01b0\u1ee3ng nguy c\u01a1: Ng\u01b0\u1eddi cao tu\u1ed5i (>70), suy gi\u00e1p ch\u01b0a ki\u1ec3m so\u00e1t, suy th\u1eadn, ti\u1ec1n s\u1eed b\u1ec7nh c\u01a1, u\u1ed1ng nhi\u1ec1u r\u01b0\u1ee3u \u2013 c\u1ea7n gi\u00e1m s\u00e1t ch\u1eb7t.<\/p>\n

T\u01b0\u01a1ng t\u00e1c thu\u1ed1c: Tr\u00e1nh ph\u1ed1i h\u1ee3p gemfibrozil, fibrat kh\u00e1c, niacin li\u1ec1u cao. Khi b\u1eaft bu\u1ed9c ph\u1ed1i h\u1ee3p c\u1ea7n c\u00e2n nh\u1eafc k\u1ef9 l\u1ee3i \u00edch v\u00e0 nguy c\u01a1.<\/p>\n

T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n

Trong qu\u00e1 tr\u00ecnh d\u00f9ng Rosuvastatin Savi 10, \u0111a s\u1ed1 t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n th\u01b0\u1eddng \u1edf m\u1ee9c \u0111\u1ed9 nh\u1eb9 v\u00e0 tho\u00e1ng qua. T\u1ec9 l\u1ec7 b\u1ec7nh nh\u00e2n ph\u1ea3i ng\u1eebng thu\u1ed1c do g\u1eb7p ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i d\u01b0\u1edbi 4%.<\/p>\n

Th\u01b0\u1eddng g\u1eb7p (\u22651\/100 \u0111\u1ebfn <1\/10): \u0111au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, t\u00e1o b\u00f3n, bu\u1ed3n n\u00f4n, \u0111au b\u1ee5ng, \u0111au c\u01a1, suy nh\u01b0\u1ee3c, ti\u1ec3u \u0111\u01b0\u1eddng.<\/p>\n

\u00cdt g\u1eb7p (\u22651\/1000 \u0111\u1ebfn <1\/100): ph\u00e1t ban, ng\u1ee9a, n\u1ed5i m\u1ec1 \u0111ay.<\/p>\n

Hi\u1ebfm g\u1eb7p (\u22651\/10000 \u0111\u1ebfn <1\/1000): gi\u1ea3m ti\u1ec3u c\u1ea7u, ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn (bao g\u1ed3m ph\u00f9 m\u1ea1ch), vi\u00eam t\u1ee5y, t\u0103ng men gan, b\u1ec7nh c\u01a1 (k\u1ec3 c\u1ea3 vi\u00eam c\u01a1), ti\u00eau c\u01a1 v\u00e2n.<\/p>\n

R\u1ea5t hi\u1ebfm (<1\/10000): v\u00e0ng da, vi\u00eam gan, vi\u00eam \u0111a d\u00e2y th\u1ea7n kinh, m\u1ea5t tr\u00ed nh\u1edb, ti\u1ec3u m\u00e1u, v\u00fa to \u1edf nam gi\u1edbi, \u0111au kh\u1edbp.<\/p>\n

Ch\u01b0a r\u00f5 t\u1ea7n su\u1ea5t: tr\u1ea7m c\u1ea3m, r\u1ed1i lo\u1ea1n gi\u1ea5c ng\u1ee7 (m\u1ea5t ng\u1ee7, \u00e1c m\u1ed9ng), ho, kh\u00f4 h\u1ecdng, ti\u00eau ch\u1ea3y, h\u1ed9i ch\u1ee9ng Stevens-Johnson, vi\u00eam g\u00e2n ho\u1eb7c \u0111\u1ee9t g\u00e2n, vi\u00eam c\u01a1 ho\u1ea1i t\u1eed trung gian mi\u1ec5n d\u1ecbch, ph\u00f9 to\u00e0n th\u00e2n.<\/p>\n

C\u00e1c b\u1ea5t th\u01b0\u1eddng tr\u00ean th\u1eadn nh\u01b0 protein ni\u1ec7u ho\u1eb7c ti\u1ec3u m\u00e1u c\u00f3 th\u1ec3 x\u1ea3y ra, th\u01b0\u1eddng tho\u00e1ng qua v\u00e0 gi\u1ea3m khi ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb.<\/p>\n

\u1ea2nh h\u01b0\u1edfng tr\u00ean c\u01a1 x\u01b0\u01a1ng bao g\u1ed3m \u0111au c\u01a1, b\u1ec7nh c\u01a1, ti\u00eau c\u01a1 v\u00e2n v\u00e0 t\u0103ng creatin kinase ph\u1ee5 thu\u1ed9c li\u1ec1u. Tr\u00ean gan c\u00f3 th\u1ec3 ghi nh\u1eadn t\u0103ng transaminase huy\u1ebft thanh nh\u01b0ng h\u1ea7u h\u1ebft m\u1ee9c t\u0103ng nh\u1eb9, kh\u00f4ng tri\u1ec7u ch\u1ee9ng v\u00e0 h\u1ed3i ph\u1ee5c.<\/p>\n

T\u01b0\u01a1ng t\u00e1c<\/h3>\n

Thu\u1ed1c kh\u00e1ng virus (atazanavir, atazanavir + ritonavir, lopinavir + ritonavir): kh\u00f4ng d\u00f9ng qu\u00e1 10 mg\/ng\u00e0y.<\/p>\n

Cyclosporin: l\u00e0m t\u0103ng \u0111\u00e1ng k\u1ec3 n\u1ed3ng \u0111\u1ed9 rosuvastatin (AUC cao g\u1ea5p ~7 l\u1ea7n), ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh ph\u1ed1i h\u1ee3p.<\/p>\n

Thu\u1ed1c \u0111\u1ed1i kh\u00e1ng vitamin K (v\u00ed d\u1ee5 warfarin): rosuvastatin c\u00f3 th\u1ec3 l\u00e0m t\u0103ng INR khi b\u1eaft \u0111\u1ea7u ho\u1eb7c t\u0103ng li\u1ec1u, c\u1ea7n theo d\u00f5i INR.<\/p>\n

Gemfibrozil, fibrat kh\u00e1c, niacin li\u1ec1u cao (>1 g\/ng\u00e0y), colchicin: t\u0103ng nguy c\u01a1 t\u1ed5n th\u01b0\u01a1ng c\u01a1, kh\u00f4ng khuy\u1ebfn c\u00e1o ph\u1ed1i h\u1ee3p v\u1edbi gemfibrozil.<\/p>\n

Thu\u1ed1c kh\u00e1ng acid ch\u1ee9a nh\u00f4m\/magnesi hydroxid: gi\u1ea3m ~50% n\u1ed3ng \u0111\u1ed9 rosuvastatin trong huy\u1ebft t\u01b0\u01a1ng n\u1ebfu d\u00f9ng \u0111\u1ed3ng th\u1eddi; u\u1ed1ng c\u00e1ch nhau 2 gi\u1edd s\u1ebd gi\u1ea3m t\u01b0\u01a1ng t\u00e1c.<\/p>\n

Erythromycin: gi\u1ea3m AUC ~20% v\u00e0 Cmax ~30% c\u1ee7a rosuvastatin.<\/p>\n

Thu\u1ed1c tr\u00e1nh thai \u0111\u01b0\u1eddng u\u1ed1ng v\u00e0 li\u1ec7u ph\u00e1p hormon thay th\u1ebf (HRT): t\u0103ng n\u1ed3ng \u0111\u1ed9 ethinyl estradiol (26%) v\u00e0 norgestrel (34%), c\u1ea7n l\u01b0u \u00fd khi l\u1ef1a ch\u1ecdn ph\u01b0\u01a1ng ph\u00e1p tr\u00e1nh thai.<\/p>\n

C\u00e1c thu\u1ed1c li\u00ean quan \u0111\u1ebfn CYP450 (fluconazol, ketoconazol, itraconazol): rosuvastatin kh\u00f4ng \u1ee9c ch\u1ebf\/c\u1ea3m \u1ee9ng CYP450, \u00edt c\u00f3 t\u01b0\u01a1ng t\u00e1c qua c\u01a1 ch\u1ebf n\u00e0y.<\/p>\n

L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n

Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh<\/p>\n

Cholesterol v\u00e0 c\u00e1c s\u1ea3n ph\u1ea9m chuy\u1ec3n h\u00f3a c\u1ee7a n\u00f3 r\u1ea5t c\u1ea7n thi\u1ebft cho s\u1ef1 ph\u00e1t tri\u1ec3n b\u00e0o thai, n\u00ean \u1ee9c ch\u1ebf HMG-CoA reductase c\u00f3 th\u1ec3 g\u00e2y nguy h\u1ea1i.<\/p>\n

N\u1ebfu ph\u00e1t hi\u1ec7n c\u00f3 thai trong khi d\u00f9ng thu\u1ed1c, ph\u1ea3i ng\u1eebng ngay.<\/p>\n

Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u \u1edf ng\u01b0\u1eddi v\u1ec1 vi\u1ec7c thu\u1ed1c b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9, nh\u01b0ng nghi\u00ean c\u1ee9u tr\u00ean chu\u1ed9t cho th\u1ea5y c\u00f3 b\u00e0i ti\u1ebft qua s\u1eefa.<\/p>\n

L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n

Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u chuy\u00ean bi\u1ec7t v\u1ec1 \u1ea3nh h\u01b0\u1edfng c\u1ee7a rosuvastatin \u0111\u1ed1i v\u1edbi kh\u1ea3 n\u0103ng l\u00e1i xe hay v\u1eadn h\u00e0nh m\u00e1y m\u00f3c. Tuy nhi\u00ean, trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n ch\u00f3ng m\u1eb7t, v\u00ec v\u1eady c\u1ea7n th\u1eadn tr\u1ecdng khi l\u00e0m vi\u1ec7c \u0111\u00f2i h\u1ecfi s\u1ef1 t\u1ec9nh t\u00e1o.<\/p>\n

Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n

Hi\u1ec7n ch\u01b0a c\u00f3 nhi\u1ec1u d\u1eef li\u1ec7u v\u1ec1 t\u00ecnh hu\u1ed1ng qu\u00e1 li\u1ec1u rosuvastatin \u1edf ng\u01b0\u1eddi.<\/p>\n

Ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u.<\/p>\n

X\u1eed tr\u00ed ch\u1ee7 y\u1ebfu l\u00e0 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 h\u1ed7 tr\u1ee3.<\/p>\n

Th\u1ea9m t\u00e1ch m\u00e1u kh\u00f4ng l\u00e0m t\u0103ng \u0111\u00e1ng k\u1ec3 th\u1ea3i tr\u1eeb rosuvastatin.<\/p>\n

B\u1ea3o qu\u1ea3n<\/h3>\n

Gi\u1eef Rosuvastatin Savi 10 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (<30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n

Kh\u00f4ng \u0111\u1ec3 Rosuvastatin Savi 10 trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n

Kh\u00f4ng s\u1eed d\u1ee5ng Rosuvastatin Savi 10 khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n

S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n

Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Rosuvastatin Savi 10 nh\u01b0:<\/p>\n

Rosuvastatin Stella 10mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 rosuvastatin h\u00e0m l\u01b0\u1ee3ng 10mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean doanh Stellapharm, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh l\u00e0m gi\u1ea3m cholesterol m\u00e1u<\/p>\n

Crestor 10mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 rosuvastatin h\u00e0m l\u01b0\u1ee3ng 10mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi IPR Pharmaceuticals Inc.,\u00a0\u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh l\u00e0m gi\u1ea3m cholesterol m\u00e1u<\/p>\n

T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n

Luvai A, Mbagaya W, Hall AS, Barth JH (2012). Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease. Clin Med Insights Cardiol. Truy c\u1eadp ng\u00e0y 28 th\u00e1ng 8 n\u0103m 2025 t\u1eeb: https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3303484\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Thu\u1ed1c Rosuvastatin Savi 10 l\u00e0m gi\u1ea3m cholesterol to\u00e0n ph\u1ea7n, LDL-C, VLDL-C v\u00e0 triglycerid, \u0111\u1ed3ng th\u1eddi gi\u00fap t\u0103ng nh\u1eb9 HDL-C theo c\u01a1 ch\u1ebf \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc men HMG-CoA reductase<\/span><\/p>\n","protected":false},"author":1,"featured_media":135539,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-135538","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/135538","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=135538"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/135539"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=135538"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=135538"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=135538"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}