{"id":135404,"date":"2025-08-27T11:30:39","date_gmt":"2025-08-27T04:30:39","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=135404"},"modified":"2026-01-04T13:02:07","modified_gmt":"2026-01-04T06:02:07","slug":"metformin-850mg-tipharco","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/metformin-850mg-tipharco\/","title":{"rendered":"Metformin 850mg Tipharco"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Metformin 850mg Tipharco \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u00f4\u0309 ph\u00e2\u0300n D\u01b0\u01a1\u0323c ph\u00e2\u0309m Tipharco, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110294000 (VD-34246-20).<\/strong><\/p>\n<h2>Metformin 850mg Tipharco l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Metformin 850mg<\/strong> Tipharco l\u00e0 m\u1ed9t thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft \u0111\u01b0\u1eddng u\u1ed1ng, m\u1ed7i vi\u00ean n\u00e9n ch\u1ee9a:<\/p>\n<ul>\n<li><strong>Metformin<\/strong> hydrochloride: 850mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: V\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110294000 (VD-34246-20)<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 4 v\u1ec9 x 15 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_135413\" aria-describedby=\"caption-attachment-135413\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-135413\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Metformin-850mg-Tipharco.jpg\" alt=\"Metformin 850mg Tipharco \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng kh\u00f4ng ph\u1ee5 thu\u1ed9c insulin t\u00edp 2\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Metformin-850mg-Tipharco.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Metformin-850mg-Tipharco-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Metformin-850mg-Tipharco-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Metformin-850mg-Tipharco-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-135413\" class=\"wp-caption-text\">Metformin 850mg Tipharco \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng kh\u00f4ng ph\u1ee5 thu\u1ed9c insulin t\u00edp 2<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Metformin 850mg Tipharco<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Metformin l\u00e0 m\u1ed9t thu\u1ed1c ch\u1ed1ng t\u0103ng \u0111\u01b0\u1eddng huy\u1ebft, gi\u00fap c\u1ea3i thi\u1ec7n kh\u1ea3 n\u0103ng dung n\u1ea1p glucose \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tu\u00fdp 2, l\u00e0m gi\u1ea3m c\u1ea3 n\u1ed3ng \u0111\u1ed9 glucose huy\u1ebft c\u01a1 b\u1ea3n v\u00e0 sau b\u1eefa \u0103n. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c ph\u1ee9c t\u1ea1p v\u00e0 \u0111a chi\u1ec1u, kh\u00e1c bi\u1ec7t ho\u00e0n to\u00e0n so v\u1edbi nh\u00f3m sulfonylurea, ch\u1ee7 y\u1ebfu th\u00f4ng qua ba c\u01a1 ch\u1ebf ch\u00ednh:<\/p>\n<ul>\n<li>\u1ee8c ch\u1ebf s\u1ea3n xu\u1ea5t glucose t\u1ea1i gan: \u0110\u00e2y l\u00e0 c\u01a1 ch\u1ebf quan tr\u1ecdng nh\u1ea5t. Metformin l\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 qu\u00e1 tr\u00ecnh t\u00e2n t\u1ea1o glucose (gluconeogenesis) v\u00e0 ly gi\u1ea3i glycogen (glycogenolysis) \u1edf gan, t\u1eeb \u0111\u00f3 gi\u1ea3m l\u01b0\u1ee3ng \u0111\u01b0\u1eddng m\u00e0 gan \u0111\u01b0a v\u00e0o m\u00e1u.<\/li>\n<li>T\u0103ng nh\u1ea1y c\u1ea3m c\u1ee7a insulin \u1edf m\u00f4 ngo\u1ea1i vi: Thu\u1ed1c c\u1ea3i thi\u1ec7n \u0111\u1ed9 nh\u1ea1y c\u1ee7a c\u00e1c th\u1ee5 th\u1ec3 insulin t\u1ea1i c\u00e1c m\u00f4 \u0111\u00edch nh\u01b0 c\u01a1 v\u00e0 m\u1ee1. \u0110i\u1ec1u n\u00e0y gi\u00fap c\u00e1c t\u1ebf b\u00e0o s\u1eed d\u1ee5ng glucose t\u1eeb m\u00e1u m\u1ed9t c\u00e1ch hi\u1ec7u qu\u1ea3 h\u01a1n, l\u00e0m gi\u1ea3m t\u00ecnh tr\u1ea1ng kh\u00e1ng insulin, v\u1ed1n l\u00e0 c\u1ed1t l\u00f5i c\u1ee7a b\u1ec7nh sinh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tu\u00fdp 2.<\/li>\n<li>L\u00e0m ch\u1eadm h\u1ea5p thu glucose t\u1ea1i ru\u1ed9t: Metformin l\u00e0m gi\u1ea3m t\u1ed1c \u0111\u1ed9 v\u00e0 m\u1ee9c \u0111\u1ed9 h\u1ea5p thu glucose t\u1eeb th\u1ee9c \u0103n \u1edf \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/li>\n<\/ul>\n<p>M\u1ed9t \u0111\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c l\u00fd quan tr\u1ecdng l\u00e0 Metformin kh\u00f4ng k\u00edch th\u00edch t\u1ebf b\u00e0o beta c\u1ee7a tuy\u1ebfn t\u1ee5y ti\u1ebft ra insulin. Do \u0111\u00f3, khi s\u1eed d\u1ee5ng \u0111\u01a1n tr\u1ecb li\u1ec7u, thu\u1ed1c kh\u00f4ng g\u00e2y ra c\u00e1c c\u01a1n h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft v\u00e0 c\u0169ng kh\u00f4ng g\u00e2y t\u0103ng insulin m\u00e1u.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Metformin \u0111\u01b0\u1ee3c h\u1ea5p thu ch\u1eadm v\u00e0 kh\u00f4ng ho\u00e0n to\u00e0n qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i kho\u1ea3ng 50-60%. Th\u1ee9c \u0103n c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m nh\u1eb9 m\u1ee9c \u0111\u1ed9 v\u00e0 t\u1ed1c \u0111\u1ed9 h\u1ea5p thu.<\/p>\n<p>Ph\u00e2n b\u1ed1: Thu\u1ed1c li\u00ean k\u1ebft kh\u00f4ng \u0111\u00e1ng k\u1ec3 v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng v\u00e0 ph\u00e2n b\u1ed1 nhanh ch\u00f3ng v\u00e0o c\u00e1c m\u00f4 v\u00e0 d\u1ecbch c\u01a1 th\u1ec3, bao g\u1ed3m c\u1ea3 h\u1ed3ng c\u1ea7u.<\/p>\n<p>V\u1ec1 m\u1eb7t chuy\u1ec3n h\u00f3a, Metformin kh\u00f4ng \u0111\u01b0\u1ee3c x\u1eed l\u00fd t\u1ea1i gan.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Thu\u1ed1c \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua th\u1eadn \u1edf d\u1ea1ng kh\u00f4ng \u0111\u1ed5i. Kho\u1ea3ng 90% li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua \u0111\u01b0\u1eddng ti\u1ec3u trong v\u00f2ng 24 gi\u1edd. \u1ede b\u1ec7nh nh\u00e2n suy th\u1eadn, \u0111\u1ed9 thanh th\u1ea3i c\u1ee7a thu\u1ed1c gi\u1ea3m, d\u1eabn \u0111\u1ebfn nguy c\u01a1 t\u00edch l\u0169y v\u00e0 t\u0103ng n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng.<\/p>\n<h2>Thu\u1ed1c Metformin 850mg Tipharco \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c Metformin 850mg Tipharco \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh l\u00e0 l\u1ef1a ch\u1ecdn \u0111\u1ea7u tay trong \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tu\u00fdp 2 \u1edf ng\u01b0\u1eddi l\u1edbn, \u0111\u1eb7c bi\u1ec7t \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n th\u1eeba c\u00e2n, khi ch\u1ebf \u0111\u1ed9 \u0103n v\u00e0 luy\u1ec7n t\u1eadp th\u1ec3 ch\u1ea5t \u0111\u01a1n thu\u1ea7n kh\u00f4ng \u0111\u1ee7 \u0111\u1ec3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft m\u1ed9t c\u00e1ch hi\u1ec7u qu\u1ea3.<\/p>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng d\u01b0\u1edbi d\u1ea1ng \u0111\u01a1n tr\u1ecb li\u1ec7u ho\u1eb7c ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng \u0111\u01b0\u1eddng u\u1ed1ng kh\u00e1c (nh\u01b0 sulfonylurea, TZD, DPP-4i, SGLT2i) ho\u1eb7c v\u1edbi insulin \u0111\u1ec3 t\u0103ng c\u01b0\u1eddng hi\u1ec7u qu\u1ea3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft.<\/p>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Metformin 850mg Tipharco<\/h2>\n<p>Li\u1ec1u l\u01b0\u1ee3ng c\u1ee7a Metformin c\u1ea7n \u0111\u01b0\u1ee3c c\u00e1 th\u1ec3 h\u00f3a d\u1ef1a tr\u00ean hi\u1ec7u qu\u1ea3 v\u00e0 kh\u1ea3 n\u0103ng dung n\u1ea1p c\u1ee7a t\u1eebng b\u1ec7nh nh\u00e2n v\u00e0 kh\u00f4ng v\u01b0\u1ee3t qu\u00e1 li\u1ec1u t\u1ed1i \u0111a khuy\u1ebfn c\u00e1o l\u00e0 2550 mg\/ng\u00e0y.<\/p>\n<ul>\n<li>Ng\u01b0\u1eddi l\u1edbn:\n<ul>\n<li>Li\u1ec1u kh\u1edfi \u0111\u1ea7u th\u00f4ng th\u01b0\u1eddng l\u00e0 850mg\/l\u1ea7n, 1 l\u1ea7n\/ng\u00e0y, u\u1ed1ng v\u00e0o b\u1eefa \u0103n s\u00e1ng.<\/li>\n<li>Sau m\u1ed7i 1-2 tu\u1ea7n, li\u1ec1u c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh t\u0103ng d\u1ea7n d\u1ef1a tr\u00ean k\u1ebft qu\u1ea3 \u0111o \u0111\u01b0\u1eddng huy\u1ebft cho \u0111\u1ebfn khi \u0111\u1ea1t \u0111\u01b0\u1ee3c li\u1ec1u \u0111\u00e1p \u1ee9ng.<\/li>\n<li>Li\u1ec1u duy tr\u00ec th\u01b0\u1eddng l\u00e0 850mg\/l\u1ea7n, 2 l\u1ea7n\/ng\u00e0y (s\u00e1ng v\u00e0 t\u1ed1i).<\/li>\n<\/ul>\n<\/li>\n<li>Ng\u01b0\u1eddi cao tu\u1ed5i: C\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng li\u1ec1u, n\u00ean b\u1eaft \u0111\u1ea7u \u1edf m\u1ee9c li\u1ec1u th\u1ea5p v\u00e0 theo d\u00f5i ch\u1eb7t ch\u1ebd ch\u1ee9c n\u0103ng th\u1eadn.<\/li>\n<li>B\u1ec7nh nh\u00e2n suy th\u1eadn: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf b\u1ec7nh nh\u00e2n c\u00f3 \u0111\u1ed9 l\u1ecdc c\u1ea7u th\u1eadn \u01b0\u1edbc t\u00ednh (eGFR) &lt; 30 mL\/ph\u00fat\/1,73 m\u00b2. C\u1ea7n \u0111\u00e1nh gi\u00e1 k\u1ef9 l\u1ee3i \u00edch v\u00e0 nguy c\u01a1 n\u1ebfu eGFR trong kho\u1ea3ng 30-45 mL\/ph\u00fat\/1,73 m\u00b2.<\/li>\n<\/ul>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Metformin 850mg Tipharco<\/h2>\n<p>Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng. \u0110\u1ec3 gi\u1ea3m thi\u1ec3u c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n tr\u00ean \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, b\u1ec7nh nh\u00e2n n\u00ean u\u1ed1ng thu\u1ed1c c\u00f9ng v\u1edbi ho\u1eb7c ngay sau b\u1eefa \u0103n.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Metformin 850mg Tipharco trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Qu\u00e1 m\u1eabn v\u1edbi Metformin hydrochloride ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c Metformin 850mg Tipharco.<\/p>\n<p>Nhi\u1ec5m toan chuy\u1ec3n h\u00f3a c\u1ea5p t\u00ednh ho\u1eb7c m\u1ea1n t\u00ednh, bao g\u1ed3m c\u1ea3 nhi\u1ec5m toan ceton do \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng.<\/p>\n<p>Suy th\u1eadn n\u1eb7ng (eGFR &lt; 30 mL\/ph\u00fat\/1,73 m\u00b2).<\/p>\n<p>C\u00e1c t\u00ecnh tr\u1ea1ng c\u1ea5p t\u00ednh c\u00f3 nguy c\u01a1 l\u00e0m thay \u0111\u1ed5i ch\u1ee9c n\u0103ng th\u1eadn nh\u01b0: m\u1ea5t n\u01b0\u1edbc, nhi\u1ec5m tr\u00f9ng n\u1eb7ng, s\u1ed1c.<\/p>\n<p>T\u00ecnh tr\u1ea1ng suy gi\u1ea3m ch\u1ee9c n\u0103ng gan, nhi\u1ec5m \u0111\u1ed9c r\u01b0\u1ee3u c\u1ea5p t\u00ednh ho\u1eb7c l\u1ea1m d\u1ee5ng r\u01b0\u1ee3u m\u1ea1n t\u00ednh.<\/p>\n<p>Suy tim m\u1ea5t b\u00f9, nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p, suy h\u00f4 h\u1ea5p ho\u1eb7c c\u00e1c t\u00ecnh tr\u1ea1ng b\u1ec7nh l\u00fd kh\u00e1c li\u00ean quan \u0111\u1ebfn thi\u1ebfu oxy m\u00f4.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Metformin 850mg Tipharco<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>C\u1ea3nh b\u00e1o quan tr\u1ecdng nh\u1ea5t: nhi\u1ec5m toan acid lactic (lactic acidosis)<\/p>\n<ul>\n<li>\u0110\u00e2y l\u00e0 m\u1ed9t bi\u1ebfn ch\u1ee9ng chuy\u1ec3n h\u00f3a c\u1ef1c k\u1ef3 hi\u1ebfm g\u1eb7p nh\u01b0ng r\u1ea5t nghi\u00eam tr\u1ecdng v\u00e0 c\u00f3 t\u1ef7 l\u1ec7 t\u1eed vong cao n\u1ebfu kh\u00f4ng \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb k\u1ecbp th\u1eddi. Nguy c\u01a1 n\u00e0y li\u00ean quan \u0111\u1ebfn s\u1ef1 t\u00edch l\u0169y Metformin trong c\u01a1 th\u1ec3.<\/li>\n<li>C\u00e1c y\u1ebfu t\u1ed1 nguy c\u01a1 ch\u00ednh l\u00e0m t\u0103ng kh\u1ea3 n\u0103ng nhi\u1ec5m toan acid lactic bao g\u1ed3m: suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn (y\u1ebfu t\u1ed1 quan tr\u1ecdng nh\u1ea5t), suy gan, nghi\u1ec7n r\u01b0\u1ee3u, suy tim sung huy\u1ebft kh\u00f4ng \u1ed5n \u0111\u1ecbnh, v\u00e0 b\u1ea5t k\u1ef3 t\u00ecnh tr\u1ea1ng n\u00e0o g\u00e2y thi\u1ebfu oxy m\u00f4 (nh\u01b0 nhi\u1ec5m tr\u00f9ng huy\u1ebft, s\u1ed1c).<\/li>\n<li>B\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c h\u01b0\u1edbng d\u1eabn \u0111\u1ec3 nh\u1eadn bi\u1ebft c\u00e1c tri\u1ec7u ch\u1ee9ng s\u1edbm nh\u01b0 m\u1ec7t m\u1ecfi, \u0111au c\u01a1, kh\u00f3 th\u1edf, bu\u1ed3n ng\u1ee7 v\u00e0 \u0111au b\u1ee5ng. N\u1ebfu nghi ng\u1edd, ph\u1ea3i ng\u01b0ng thu\u1ed1c ngay l\u1eadp t\u1ee9c v\u00e0 t\u00ecm ki\u1ebfm s\u1ef1 ch\u0103m s\u00f3c y t\u1ebf kh\u1ea9n c\u1ea5p.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>R\u1ea5t ph\u1ed5 bi\u1ebfn\/Th\u01b0\u1eddng g\u1eb7p (\u1ea3nh h\u01b0\u1edfng &gt;1\/10 ho\u1eb7c &gt;1\/100 ng\u01b0\u1eddi d\u00f9ng):<\/p>\n<ul>\n<li>Tr\u00ean h\u1ec7 ti\u00eau h\u00f3a: Bu\u1ed3n n\u00f4n, n\u00f4n, ti\u00eau ch\u1ea3y, \u0111au b\u1ee5ng, ch\u00e1n \u0103n v\u00e0 c\u00f3 v\u1ecb kim lo\u1ea1i trong mi\u1ec7ng. \u0110\u00e2y l\u00e0 nh\u1eefng t\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn nh\u1ea5t, th\u01b0\u1eddng x\u1ea3y ra khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb. C\u00e1c tri\u1ec7u ch\u1ee9ng n\u00e0y th\u01b0\u1eddng c\u00f3 t\u00ednh ch\u1ea5t t\u1ea1m th\u1eddi v\u00e0 s\u1ebd gi\u1ea3m d\u1ea7n theo th\u1eddi gian.<\/li>\n<\/ul>\n<p>\u00cdt g\u1eb7p:<\/p>\n<ul>\n<li>Tr\u00ean chuy\u1ec3n h\u00f3a: Gi\u1ea3m h\u1ea5p thu vitamin B12 khi s\u1eed d\u1ee5ng k\u00e9o d\u00e0i, c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn thi\u1ebfu m\u00e1u h\u1ed3ng c\u1ea7u kh\u1ed5ng l\u1ed3.<\/li>\n<\/ul>\n<p>R\u1ea5t hi\u1ebfm g\u1eb7p (\u1ea3nh h\u01b0\u1edfng &lt;1\/10.000 ng\u01b0\u1eddi d\u00f9ng):<\/p>\n<ul>\n<li>Nhi\u1ec5m toan acid lactic.<\/li>\n<li>Bi\u1ec3u hi\u1ec7n d\u1ecb \u1ee9ng da: ban \u0111\u1ecf, ng\u1ee9a, m\u00e0y \u0111ay.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Thu\u1ed1c c\u1ea3n quang ch\u1ee9a iod: Ph\u1ea3i t\u1ea1m ng\u01b0ng Metformin tr\u01b0\u1edbc v\u00e0 trong 48 gi\u1edd sau khi th\u1ef1c hi\u1ec7n c\u00e1c th\u1ee7 thu\u1eadt ch\u1ea9n \u0111o\u00e1n h\u00ecnh \u1ea3nh c\u00f3 s\u1eed d\u1ee5ng thu\u1ed1c c\u1ea3n quang ch\u1ee9a iod \u0111\u1ec3 tr\u00e1nh nguy c\u01a1 suy th\u1eadn c\u1ea5p.<\/p>\n<p>Vi\u1ec7c s\u1eed d\u1ee5ng r\u01b0\u1ee3u \u0111\u1ed3ng th\u1eddi v\u1edbi thu\u1ed1c s\u1ebd l\u00e0m gia t\u0103ng \u0111\u00e1ng k\u1ec3 nguy c\u01a1 b\u1ecb nhi\u1ec5m toan acid lactic, m\u1ed9t bi\u1ebfn ch\u1ee9ng r\u1ea5t nguy hi\u1ec3m.<\/p>\n<p>C\u00e1c thu\u1ed1c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ch\u1ee9c n\u0103ng th\u1eadn (NSAIDs, ACEI, ARB): C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn, t\u0103ng nguy c\u01a1 t\u00edch l\u0169y Metformin.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai: Metformin b\u1ecb ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh. Insulin l\u00e0 li\u1ec7u ph\u00e1p \u0111\u01b0\u1ee3c \u01b0u ti\u00ean \u0111\u1ec3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft trong su\u1ed1t thai k\u1ef3.<\/p>\n<p>B\u00e0 m\u1eb9 cho con b\u00fa: C\u1ea7n c\u00e2n nh\u1eafc gi\u1eefa l\u1ee3i \u00edch c\u1ee7a vi\u1ec7c cho con b\u00fa v\u00e0 l\u1ee3i \u00edch c\u1ee7a vi\u1ec7c \u0111i\u1ec1u tr\u1ecb cho m\u1eb9 \u0111\u1ec3 quy\u1ebft \u0111\u1ecbnh ng\u01b0ng cho con b\u00fa hay ng\u01b0ng d\u00f9ng Metformin.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Metformin \u0111\u01a1n tr\u1ecb li\u1ec7u kh\u00f4ng g\u00e2y h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft v\u00e0 do \u0111\u00f3 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe hay v\u1eadn h\u00e0nh m\u00e1y m\u00f3c, tuy nhi\u00ean, c\u1ea7n th\u1eadn tr\u1ecdng khi ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft kh\u00e1c c\u00f3 nguy c\u01a1 g\u00e2y h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>U\u1ed1ng Metformin li\u1ec1u cao (l\u00ean \u0111\u1ebfn 85g) kh\u00f4ng g\u00e2y h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, nh\u01b0ng c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn nhi\u1ec5m toan acid lactic. \u0110\u00e2y l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng c\u1ea5p c\u1ee9u y t\u1ebf v\u00e0 \u0111\u00f2i h\u1ecfi ph\u1ea3i nh\u1eadp vi\u1ec7n ngay l\u1eadp t\u1ee9c. Ph\u01b0\u01a1ng ph\u00e1p hi\u1ec7u qu\u1ea3 nh\u1ea5t \u0111\u1ec3 lo\u1ea1i b\u1ecf lactate v\u00e0 Metformin ra kh\u1ecfi c\u01a1 th\u1ec3 l\u00e0 th\u1ea9m t\u00e1ch m\u00e1u (l\u1ecdc m\u00e1u).<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n thu\u1ed1c Metformin 850mg Tipharco \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t, nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30\u00b0C, tr\u00e1nh \u00e1nh s\u00e1ng tr\u1ef1c ti\u1ebfp v\u00e0 \u0111\u1ec3 xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Metformin 850mg Tipharco<\/h2>\n<p>Tr\u00ean th\u1ecb tr\u01b0\u1eddng c\u00f3 nhi\u1ec1u s\u1ea3n ph\u1ea9m ch\u1ee9a ho\u1ea1t ch\u1ea5t Metformin hydrochloride 850mg. M\u1ed9t trong nh\u1eefng s\u1ea3n ph\u1ea9m ph\u1ed5 bi\u1ebfn l\u00e0 thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/metformin-stella-850mg\/\">Metformin Stella 850mg<\/a>, do c\u00f4ng ty Stellapharm s\u1ea3n xu\u1ea5t, c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t, h\u00e0m l\u01b0\u1ee3ng v\u00e0 ch\u1ec9 \u0111\u1ecbnh t\u01b0\u01a1ng t\u1ef1 nh\u01b0 Metformin 850mg Tipharco.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Traci E LaMoia, Gerald I Shulman. Cellular and Molecular Mechanisms of Metformin Action, truy c\u1eadp ng\u00e0y 27 th\u00e1ng 08 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32897388\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32897388\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>S\u1ea3n ph\u1ea9m thu\u1ed1c Metformin 850mg Tipharco \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u00f4\u0309 ph\u00e2\u0300n D\u01b0\u01a1\u0323c ph\u00e2\u0309m Tipharco, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110294000 (VD-34246-20), \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tu\u00fdp II.<\/p>\n","protected":false},"author":1,"featured_media":135409,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-135404","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/135404","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=135404"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/135409"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=135404"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=135404"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=135404"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}