{"id":135357,"date":"2025-08-27T17:55:01","date_gmt":"2025-08-27T10:55:01","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=135357"},"modified":"2025-08-27T18:05:56","modified_gmt":"2025-08-27T11:05:56","slug":"aspirin-ph8-mekophar","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/aspirin-ph8-mekophar\/","title":{"rendered":"Aspirin pH8 Mekophar"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <a href=\"https:\/\/vnras.com\/drug\/\">d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Aspirin pH8 Mekophar \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n ho\u00e1 d\u01b0\u1ee3c ph\u1ea9m Mekophar c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-15513-11<\/strong><\/p>\n<h2>Aspirin pH8 Mekophar l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ng Aspirin pH8 Mekophar<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t: Acid acetylsalicylic 500mg.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: Colloidal silicon dioxyd, natri starch glycolat, acid stearic, pregelatinized starch (Lycatab C), lactose monohydrat, methacrylic acid copolymer L-100, talc.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim tan trong ru\u1ed9t<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-15513-11<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 20 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Aspirin pH8 Mekophar<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Acid acetylsalicylic (aspirin) c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf enzym cyclooxygenase (COX), l\u00e0m gi\u1ea3m t\u1ed5ng h\u1ee3p prostaglandin \u2013 ch\u1ea5t trung gian g\u00e2y vi\u00eam, \u0111au v\u00e0 s\u1ed1t. \u0110\u1ed3ng th\u1eddi, aspirin c\u00f2n t\u00e1c \u0111\u1ed9ng l\u00ean ti\u1ec3u c\u1ea7u, ng\u0103n ng\u1eeba s\u1ef1 k\u1ebft t\u1eadp, t\u1eeb \u0111\u00f3 l\u00e0m gi\u1ea3m nguy c\u01a1 h\u00ecnh th\u00e0nh huy\u1ebft kh\u1ed1i. V\u1edbi d\u1ea1ng vi\u00ean bao tan trong ru\u1ed9t, thu\u1ed1c gi\u00fap h\u1ea1n ch\u1ebf k\u00edch \u1ee9ng ni\u00eam m\u1ea1c d\u1ea1 d\u00e0y so v\u1edbi vi\u00ean n\u00e9n th\u00f4ng th\u01b0\u1eddng.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Sau khi u\u1ed1ng, aspirin \u0111\u01b0\u1ee3c h\u1ea5p thu ch\u1ee7 y\u1ebfu t\u1ea1i ru\u1ed9t non. Trong c\u01a1 th\u1ec3, aspirin nhanh ch\u00f3ng b\u1ecb th\u1ee7y ph\u00e2n th\u00e0nh acid salicylic \u2013 ch\u1ea5t c\u00f3 ho\u1ea1t t\u00ednh d\u01b0\u1ee3c l\u00fd ch\u00ednh. Salicylat li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng v\u00e0 ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i v\u00e0o m\u00f4, c\u00f3 kh\u1ea3 n\u0103ng qua nhau thai v\u00e0 ti\u1ebft v\u00e0o s\u1eefa m\u1eb9. Thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a \u1edf gan, th\u1ea3i tr\u1eeb qua th\u1eadn d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i ho\u1eb7c li\u00ean h\u1ee3p glucuronid. T\u1ed1c \u0111\u1ed9 th\u1ea3i tr\u1eeb ph\u1ee5 thu\u1ed9c v\u00e0o pH n\u01b0\u1edbc ti\u1ec3u, t\u0103ng l\u00ean khi n\u01b0\u1edbc ti\u1ec3u ki\u1ec1m.<\/p>\n<h2>Thu\u1ed1c Aspirin pH8 Mekophar \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Gi\u1ea3m \u0111au m\u1ee9c \u0111\u1ed9 nh\u1eb9 \u0111\u1ebfn v\u1eeba nh\u01b0 \u0111au \u0111\u1ea7u, \u0111au r\u0103ng, \u0111au c\u01a1.<\/p>\n<p>H\u1ea1 s\u1ed1t trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p s\u1ed1t do nhi\u1ec5m khu\u1ea9n ho\u1eb7c c\u1ea3m c\u00fam.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb vi\u00eam c\u1ea5p v\u00e0 m\u1ea1n t\u00ednh: vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p, vi\u00eam kh\u1edbp thi\u1ebfu ni\u00ean, tho\u00e1i h\u00f3a kh\u1edbp, vi\u00eam c\u1ed9t s\u1ed1ng d\u00ednh kh\u1edbp.<\/p>\n<figure id=\"attachment_135371\" aria-describedby=\"caption-attachment-135371\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-135371\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Aspirin-pH8-Mekophar.jpg\" alt=\"Aspirin pH8 Mekophar\" width=\"1200\" height=\"900\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Aspirin-pH8-Mekophar.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Aspirin-pH8-Mekophar-533x400.jpg 533w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Aspirin-pH8-Mekophar-1067x800.jpg 1067w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Aspirin-pH8-Mekophar-768x576.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Aspirin-pH8-Mekophar-350x263.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-135371\" class=\"wp-caption-text\">Thu\u1ed1c Aspirin pH8 Mekophar l\u00e0 thu\u1ed1c ch\u1ee9a ho\u1ea1t ch\u1ea5t Acid acetylsalicylic, c\u00f3 t\u00e1c d\u1ee5ng h\u1ea1 s\u1ed1t, gi\u1ea3m \u0111au m\u1ee9c \u0111\u1ed9 nh\u1eb9 \u0111\u1ebfn v\u1eeba v\u00e0 ch\u1ed1ng vi\u00eam trong c\u00e1c b\u1ec7nh l\u00fd kh\u1edbp.<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Ng\u01b0\u1eddi l\u1edbn:<\/p>\n<p>Gi\u1ea3m \u0111au, h\u1ea1 s\u1ed1t: 1\u20132 vi\u00ean\/l\u1ea7n, c\u00f3 th\u1ec3 nh\u1eafc l\u1ea1i sau 4\u20136 gi\u1edd, t\u1ed1i \u0111a 8 vi\u00ean\/ng\u00e0y.<\/p>\n<p>T\u00e1c d\u1ee5ng ch\u1ed1ng vi\u00eam:<\/p>\n<p>Vi\u00eam c\u1ea5p: 4\u20138g\/ng\u00e0y, chia th\u00e0nh nhi\u1ec1u li\u1ec1u nh\u1ecf.<\/p>\n<p>Vi\u00eam m\u1ea1n: t\u1edbi 5g\/ng\u00e0y, chia th\u00e0nh nhi\u1ec1u l\u1ea7n.<\/p>\n<p>Tr\u1ebb em (ch\u1ec9 d\u00f9ng trong ch\u1ec9 \u0111\u1ecbnh vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p thi\u1ebfu ni\u00ean, do nguy c\u01a1 h\u1ed9i ch\u1ee9ng Reye):<\/p>\n<p>Li\u1ec1u khuy\u1ebfn c\u00e1o kho\u1ea3ng 60mg\/kg\/ng\u00e0y, chia 4\u20136 l\u1ea7n.<\/p>\n<p>Tr\u1ebb 30\u201340kg (9\u201313 tu\u1ed5i): 1 vi\u00ean\/l\u1ea7n, c\u00e1ch nhau 6 gi\u1edd, t\u1ed1i \u0111a 4 vi\u00ean\/ng\u00e0y.<\/p>\n<p>Tr\u1ebb 41\u201350kg (12\u201315 tu\u1ed5i): 1 vi\u00ean\/l\u1ea7n, c\u00e1ch nhau 4 gi\u1edd, t\u1ed1i \u0111a 6 vi\u00ean\/ng\u00e0y.<\/p>\n<p>Th\u1eddi gian d\u00f9ng thu\u1ed1c: Kh\u00f4ng qu\u00e1 3 ng\u00e0y khi h\u1ea1 s\u1ed1t v\u00e0 5 ng\u00e0y khi gi\u1ea3m \u0111au n\u1ebfu kh\u00f4ng c\u00f3 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a b\u00e1c s\u0129.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>U\u1ed1ng nguy\u00ean <b>vi\u00ean n\u00e9n Aspirin pH8 Mekophar<\/b> v\u1edbi n\u01b0\u1edbc, s\u1eefa ho\u1eb7c n\u01b0\u1edbc tr\u00e1i c\u00e2y.<\/p>\n<p>Kh\u00f4ng \u0111\u01b0\u1ee3c nghi\u1ec1n ho\u1eb7c nhai \u0111\u1ec3 tr\u00e1nh l\u00e0m m\u1ea5t t\u00e1c d\u1ee5ng bao tan trong ru\u1ed9t.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Aspirin pH8 Mekophar trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>D\u1ecb \u1ee9ng v\u1edbi aspirin ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>Ti\u1ec1n s\u1eed hen suy\u1ec5n ho\u1eb7c d\u1ecb \u1ee9ng v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid.<\/p>\n<p>Ng\u01b0\u1eddi \u0111ang m\u1eafc b\u1ec7nh xu\u1ea5t huy\u1ebft, gi\u1ea3m ti\u1ec3u c\u1ea7u, lo\u00e9t d\u1ea1 d\u00e0y \u2013 t\u00e1 tr\u00e0ng ti\u1ebfn tri\u1ec3n.<\/p>\n<p>B\u1ec7nh nh\u00e2n suy gan, suy th\u1eadn n\u1eb7ng ho\u1eb7c suy tim m\u1ee9c \u0111\u1ed9 v\u1eeba \u2013 n\u1eb7ng.<\/p>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai t\u1eeb tu\u1ea7n th\u1ee9 24 tr\u1edf \u0111i khi d\u00f9ng li\u1ec1u tr\u00ean 100mg\/ng\u00e0y.<\/p>\n<p>Ng\u01b0\u1eddi \u0111ang \u0111i\u1ec1u tr\u1ecb b\u1eb1ng methotrexat li\u1ec1u cao, thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng \u0111\u01b0\u1eddng u\u1ed1ng ho\u1eb7c c\u00e1c thu\u1ed1c ch\u1ed1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u kh\u00e1c.<\/p>\n<p>Tr\u1ebb em d\u01b0\u1edbi 6 tu\u1ed5i do nguy c\u01a1 s\u1eb7c khi nu\u1ed1t vi\u00ean.<\/p>\n<p>Kh\u00f4ng d\u00f9ng d\u1ea1ng 500mg cho tr\u1ebb d\u01b0\u1edbi 30kg.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Ki\u1ec3m tra k\u1ef9 c\u00e1c thu\u1ed1c \u0111ang s\u1eed d\u1ee5ng \u0111\u1ec3 tr\u00e1nh tr\u00f9ng l\u1eb7p th\u00e0nh ph\u1ea7n aspirin.<\/p>\n<p>S\u1eed d\u1ee5ng k\u00e9o d\u00e0i li\u1ec1u cao c\u00f3 th\u1ec3 g\u00e2y t\u1ed5n th\u01b0\u01a1ng th\u1eadn m\u1ea1n t\u00ednh.<\/p>\n<p>Nguy c\u01a1 xu\u1ea5t huy\u1ebft ti\u00eau h\u00f3a, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi cao tu\u1ed5i, ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed lo\u00e9t d\u1ea1 d\u00e0y ho\u1eb7c \u0111ang d\u00f9ng thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng.<\/p>\n<p>H\u1ed9i ch\u1ee9ng Reye c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf tr\u1ebb em d\u00f9ng aspirin khi m\u1eafc b\u1ec7nh virus (th\u1ee7y \u0111\u1eadu, c\u00fam).<\/p>\n<p>Ng\u01b0\u1eddi thi\u1ebfu men G6PD c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i ch\u1eb7t ch\u1ebd do nguy c\u01a1 tan m\u00e1u.<\/p>\n<p>C\u1ea7n l\u01b0u \u00fd khi s\u1eed d\u1ee5ng \u1edf b\u1ec7nh nh\u00e2n suy gan, suy th\u1eadn, suy tim nh\u1eb9 ho\u1eb7c hen ph\u1ebf qu\u1ea3n.<\/p>\n<p>Ng\u01b0\u1eddi cao tu\u1ed5i d\u1ec5 b\u1ecb ng\u1ed9 \u0111\u1ed9c aspirin, n\u00ean d\u00f9ng li\u1ec1u th\u1ea5p h\u01a1n.<\/p>\n<p>Thu\u1ed1c c\u00f3 ch\u1ee9a lactose, th\u1eadn tr\u1ecdng \u1edf b\u1ec7nh nh\u00e2n kh\u00f4ng dung n\u1ea1p galactose ho\u1eb7c m\u1eafc r\u1ed1i lo\u1ea1n h\u1ea5p thu glucose-galactose.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p (\u22651\/100 \u2013 &lt;1\/10): bu\u1ed3n n\u00f4n, n\u00f4n, kh\u00f3 ti\u00eau, \u0111au th\u01b0\u1ee3ng v\u1ecb, \u1ee3 n\u00f3ng, lo\u00e9t d\u1ea1 d\u00e0y \u2013 t\u00e1 tr\u00e0ng; \u00f9 tai, nh\u1ee9c \u0111\u1ea7u; ph\u00e1t ban da; thi\u1ebfu m\u00e1u tan m\u00e1u; kh\u00f3 th\u1edf.<\/p>\n<p>\u00cdt g\u1eb7p (\u22651\/1.000 \u2013 &lt;1\/100): m\u1ea5t ng\u1ee7, b\u1ed3n ch\u1ed3n, c\u00e1u g\u1eaft; thi\u1ebfu m\u00e1u do thi\u1ebfu s\u1eaft; ch\u1ea3y m\u00e1u k\u00e9o d\u00e0i, gi\u1ea3m ti\u1ec3u c\u1ea7u, gi\u1ea3m b\u1ea1ch c\u1ea7u; t\u1ed5n th\u01b0\u01a1ng gan, suy th\u1eadn; co th\u1eaft ph\u1ebf qu\u1ea3n.<\/p>\n<p>Hi\u1ebfm g\u1eb7p: ph\u1ea3n v\u1ec7, s\u1ed1c ph\u1ea3n v\u1ec7, xu\u1ea5t huy\u1ebft ti\u00eau h\u00f3a n\u1eb7ng.<\/p>\n<p>Ng\u01b0\u1eddi b\u1ec7nh c\u1ea7n ng\u1eebng thu\u1ed1c v\u00e0 th\u00f4ng b\u00e1o ngay cho b\u00e1c s\u0129\/d\u01b0\u1ee3c s\u0129 khi g\u1eb7p t\u00e1c d\u1ee5ng ph\u1ee5.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c thu\u1ed1c<\/h3>\n<p>Nguy c\u01a1 t\u0103ng xu\u1ea5t huy\u1ebft khi d\u00f9ng chung v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u (clopidogrel, ticlopidin, abciximab, eptifibatid, tirofiban\u2026), thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng, heparin, thu\u1ed1c ti\u00eau s\u1ee3i huy\u1ebft.<\/p>\n<p><em><strong>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh khi ph\u1ed1i h\u1ee3p\u00a0<\/strong><\/em><\/p>\n<p>Methotrexat \u2265 20mg\/tu\u1ea7n do t\u0103ng \u0111\u1ed9c t\u00ednh huy\u1ebft h\u1ecdc.<\/p>\n<p>Thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng \u0111\u01b0\u1eddng u\u1ed1ng c\u00f9ng li\u1ec1u kh\u00e1ng vi\u00eam hay gi\u1ea3m \u0111au\/h\u1ea1 s\u1ed1t c\u1ee7a aspirin \u1edf b\u1ec7nh nh\u00e2n lo\u00e9t d\u1ea1 d\u00e0y &#8211; t\u00e1 tr\u00e0ng.<\/p>\n<p><em><strong>Kh\u00f4ng khuy\u1ebfn kh\u00edch ph\u1ed1i h\u1ee3p<\/strong><\/em><\/p>\n<p>Thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng \u0111\u01b0\u1eddng u\u1ed1ng \u1edf li\u1ec1u h\u1ea1 s\u1ed1t ho\u1eb7c ch\u1ed1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u \u1edf b\u1ec7nh nh\u00e2n c\u00f3 ho\u1eb7c kh\u00f4ng c\u00f3 ti\u1ec1n s\u1eed lo\u00e9t.<\/p>\n<p>NSAIDs kh\u00e1c, t\u0103ng nguy c\u01a1 lo\u00e9t\/xu\u1ea5t huy\u1ebft ti\u00eau h\u00f3a.<\/p>\n<p>Glucocorticoid (tr\u1eeb hydrocortison li\u1ec1u thay th\u1ebf).<\/p>\n<p>Heparin (tr\u1ecdng l\u01b0\u1ee3ng ph\u00e2n t\u1eed th\u1ea5p ho\u1eb7c kh\u00f4ng ph\u00e2n \u0111o\u1ea1n), \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi cao tu\u1ed5i, li\u1ec1u \u0111i\u1ec1u tr\u1ecb ho\u1eb7c ph\u1ed1i h\u1ee3p v\u1edbi aspirin kh\u00e1ng vi\u00eam\/h\u1ea1 s\u1ed1t.<\/p>\n<p>Pemetrexed khi b\u1ec7nh nh\u00e2n suy th\u1eadn m\u1ee9c nh\u1eb9 &#8211; trung b\u00ecnh (ClCr 45\u201380 ml\/ph\u00fat).<\/p>\n<p>Thu\u1ed1c t\u0103ng th\u1ea3i acid uric (probenecid, benzbromaron, sulphinpyrazon).<\/p>\n<p><em><strong>M\u1ed9t s\u1ed1 thu\u1ed1c kh\u00e1c<\/strong><\/em><\/p>\n<p>Sulphonylur\u00ea, phenytoin, acid valproic \u2192 t\u0103ng n\u1ed3ng \u0111\u1ed9 v\u00e0 \u0111\u1ed9c t\u00ednh.<\/p>\n<p>Thu\u1ed1c \u1ee9c ch\u1ebf t\u00e1i h\u1ea5p thu serotonin (SSRI) \u2192 t\u0103ng nguy c\u01a1 xu\u1ea5t huy\u1ebft.<\/p>\n<p>T\u01b0\u01a1ng t\u00e1c kh\u00e1c: aspirin l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng l\u1ee3i ti\u1ec3u c\u1ee7a spironolacton; \u1ea3nh h\u01b0\u1edfng v\u1eadn chuy\u1ec3n t\u00edch c\u1ef1c penicillin.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<h4>Ph\u1ee5 n\u1eef c\u00f3 thai<\/h4>\n<p>Vi\u1ec7c \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p prostaglandin c\u00f3 th\u1ec3 t\u00e1c \u0111\u1ed9ng ti\u00eau c\u1ef1c \u0111\u1ebfn thai k\u1ef3 v\u00e0 s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a thai nhi. Nghi\u00ean c\u1ee9u d\u1ecbch t\u1ec5 ghi nh\u1eadn nguy c\u01a1 s\u1ea3y thai, d\u1ecb t\u1eadt tim v\u00e0 tho\u00e1t v\u1ecb th\u00e0nh b\u1ee5ng t\u0103ng cao h\u01a1n khi d\u00f9ng thu\u1ed1c \u1ee9c ch\u1ebf prostaglandin trong giai \u0111o\u1ea1n \u0111\u1ea7u thai k\u1ef3. T\u1ef7 l\u1ec7 d\u1ecb t\u1eadt tim b\u1ea9m sinh c\u00f3 th\u1ec3 t\u0103ng t\u1eeb &lt;1% l\u00ean kho\u1ea3ng 1,5%, v\u00e0 m\u1ee9c \u0111\u1ed9 nguy c\u01a1 ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec1u c\u00f9ng th\u1eddi gian s\u1eed d\u1ee5ng.<\/p>\n<p>Trong 24 tu\u1ea7n \u0111\u1ea7u thai k\u1ef3, acid acetylsalicylic ch\u1ec9 \u0111\u01b0\u1ee3c d\u00f9ng khi th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft, v\u1edbi li\u1ec1u th\u1ea5p nh\u1ea5t v\u00e0 th\u1eddi gian ng\u1eafn nh\u1ea5t c\u00f3 th\u1ec3.<\/p>\n<p>\u1ede 3 th\u00e1ng cu\u1ed1i, thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y: \u0111\u00f3ng s\u1edbm \u1ed1ng \u0111\u1ed9ng m\u1ea1ch, t\u0103ng \u00e1p ph\u1ed5i, suy th\u1eadn d\u1eabn \u0111\u1ebfn thi\u1ec3u \u1ed1i \u1edf thai nhi; k\u00e9o d\u00e0i th\u1eddi gian ch\u1ea3y m\u00e1u ngay c\u1ea3 \u1edf li\u1ec1u nh\u1ecf; \u1ee9c ch\u1ebf co b\u00f3p t\u1eed cung l\u00e0m tr\u00ec ho\u00e3n ho\u1eb7c k\u00e9o d\u00e0i qu\u00e1 tr\u00ecnh sinh n\u1edf. V\u00ec v\u1eady, ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng trong 3 th\u00e1ng cu\u1ed1i thai k\u1ef3.<\/p>\n<h4>Ph\u1ee5 n\u1eef cho con b\u00fa<\/h4>\n<p>Acid acetylsalicylic b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9, do \u0111\u00f3 kh\u00f4ng n\u00ean d\u00f9ng trong th\u1eddi k\u1ef3 cho con b\u00fa.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Khi s\u1eed d\u1ee5ng Aspirin pH8 Mekophar c\u00f3 th\u1ec3 g\u00e2y m\u1ec7t m\u1ecfi, m\u1ea5t ng\u1ee7; c\u1ea7n th\u1eadn tr\u1ecdng v\u1edbi ng\u01b0\u1eddi \u0111i\u1ec1u khi\u1ec3n ph\u01b0\u01a1ng ti\u1ec7n, v\u1eadn h\u00e0nh m\u00e1y m\u00f3c ho\u1eb7c l\u00e0m vi\u1ec7c tr\u00ean cao.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Li\u1ec1u \u0111\u1ed9c: kho\u1ea3ng 200 mg\/kg \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 100 mg\/kg \u1edf tr\u1ebb nh\u1ecf. Li\u1ec1u 25\u201330 g c\u00f3 th\u1ec3 g\u00e2y t\u1eed vong. N\u1ed3ng \u0111\u1ed9 salicylat trong m\u00e1u &gt;300 mg\/L c\u00f3 th\u1ec3 g\u00e2y \u0111\u1ed9c, &gt;500 mg\/L (ng\u01b0\u1eddi l\u1edbn) ho\u1eb7c &gt;300 mg\/L (tr\u1ebb em) th\u01b0\u1eddng g\u00e2y ng\u1ed9 \u0111\u1ed9c n\u1eb7ng.<\/p>\n<p><em><strong>Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u:<\/strong><\/em> \u00f9 tai, r\u1ed1i lo\u1ea1n th\u00ednh gi\u00e1c, nh\u1ee9c \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng. Tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng: ki\u1ec1m h\u00f4 h\u1ea5p, sau \u0111\u00f3 toan chuy\u1ec3n h\u00f3a, t\u0103ng th\u00e2n nhi\u1ec7t, m\u1ea5t n\u01b0\u1edbc, co gi\u1eadt, \u1ea3o gi\u00e1c, h\u00f4n m\u00ea, suy h\u00f4 h\u1ea5p, t\u1ee5t huy\u1ebft \u00e1p, ng\u1eebng tim.<\/p>\n<p><em><strong>X\u1eed tr\u00ed<\/strong><\/em><\/p>\n<p>R\u1eeda d\u1ea1 d\u00e0y, than ho\u1ea1t t\u00ednh, ki\u1ec3m so\u00e1t h\u00f4 h\u1ea5p, b\u00f9 d\u1ecbch v\u00e0 \u0111i\u1ec7n gi\u1ea3i, \u0111i\u1ec1u ch\u1ec9nh r\u1ed1i lo\u1ea1n acid\u2013base, h\u1ea1 s\u1ed1t.<\/p>\n<p>Theo d\u00f5i n\u1ed3ng \u0111\u1ed9 salicylat m\u00e1u li\u00ean t\u1ee5c.<\/p>\n<p>T\u0103ng \u0111\u00e0o th\u1ea3i b\u1eb1ng ki\u1ec1m h\u00f3a n\u01b0\u1edbc ti\u1ec3u, th\u1ea9m t\u00e1ch m\u00e1u ho\u1eb7c thay m\u00e1u khi ng\u1ed9 \u0111\u1ed9c n\u1eb7ng.<\/p>\n<p>Ki\u1ec3m so\u00e1t co gi\u1eadt, \u0111i\u1ec1u tr\u1ecb h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft n\u1ebfu c\u00f3.<\/p>\n<p>C\u00f3 th\u1ec3 d\u00f9ng vitamin K trong tr\u01b0\u1eddng h\u1ee3p xu\u1ea5t huy\u1ebft k\u00e9o d\u00e0i.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Aspirin pH8 Mekophar \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Aspirin pH8 Mekophar trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Aspirin pH8 Mekophar khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Aspirin pH8 Mekophar nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/aspirin-ph8-500mg-quapharco\/\">Aspirin pH8 500mg Quapharco<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Acid acetylsalicylic v\u1edbi h\u00e0m l\u01b0\u1ee3ng 500mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Qu\u1ea3ng B\u00ecnh, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh gi\u1ea3m \u0111au, ch\u1ed1ng vi\u00eam, h\u1ea1 s\u1ed1t<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/aspirin-100-traphaco\/\">Aspirin-100 Traphaco<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Acid acetylsalicylic v\u1edbi h\u00e0m l\u01b0\u1ee3ng 100mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Traphaco H\u01b0ng Y\u00ean, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh gi\u1ea3m \u0111au, ch\u1ed1ng vi\u00eam, h\u1ea1 s\u1ed1t<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Aspirin pH8 Mekophar \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/To-huong-dan-su-dung-Aspirin-pH8-Mekophar-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 27 th\u00e1ng 8 n\u0103m 2025<\/li>\n<li>Dai Y, Ge J (2012). Clinical use of aspirin in treatment and prevention of cardiovascular disease. Thrombosis. Truy c\u1eadp ng\u00e0y 27 th\u00e1ng 8 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3236445\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3236445\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Aspirin pH8 Mekophar l\u00e0 thu\u1ed1c ch\u1ee9a ho\u1ea1t ch\u1ea5t ch\u00ednh l\u00e0 Acid acetylsalicylic, c\u00f3 t\u00e1c d\u1ee5ng h\u1ea1 s\u1ed1t, gi\u1ea3m \u0111au m\u1ee9c \u0111\u1ed9 nh\u1eb9 \u0111\u1ebfn v\u1eeba v\u00e0 ch\u1ed1ng vi\u00eam trong c\u00e1c b\u1ec7nh l\u00fd kh\u1edbp.<\/p>\n","protected":false},"author":1,"featured_media":135358,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-135357","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/135357","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=135357"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/135358"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=135357"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=135357"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=135357"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}