{"id":133417,"date":"2025-08-19T03:27:31","date_gmt":"2025-08-18T20:27:31","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=133417"},"modified":"2025-08-19T09:58:12","modified_gmt":"2025-08-19T02:58:12","slug":"duoplavin-75mg-100mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/duoplavin-75mg-100mg\/","title":{"rendered":"Duoplavin 75mg\/100mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <\/strong><a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c <a href=\"https:\/\/vnras.com\/drug\/duoplavin-75mg-100mg\/\">Duoplavin 75mg\/100mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Sanofi, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 300110793024 (S\u0110K c\u0169: VN-22466-19).<\/strong><\/p>\n<h2>Duoplavin 75mg\/100mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Thu\u1ed1c Duoplavin 75mg\/100mg<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li>Clopidogrel 75mg<\/li>\n<li>Acetylsalicylic acid 100mg<\/li>\n<li>Ph\u1ee5 li\u1ec7u v\u0111<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 300110793024 (S\u0110K c\u0169: VN-22466-19)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Ph\u00e1p<\/p>\n<figure id=\"attachment_133433\" aria-describedby=\"caption-attachment-133433\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-133433\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/duoplavin-75mg-100mg.jpg\" alt=\"Duoplavin 75mg\/100mg\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/duoplavin-75mg-100mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/duoplavin-75mg-100mg-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/duoplavin-75mg-100mg-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/duoplavin-75mg-100mg-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-133433\" class=\"wp-caption-text\">Duoplavin 75mg\/100mg ng\u0103n ng\u1eeba h\u00ecnh th\u00e0nh huy\u1ebft kh\u1ed1i<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Duoplavin 75mg\/100mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p><em>Clopidogrel<\/em><\/p>\n<p>Clopidogrel \u0111\u01b0\u1ee3c men CYP450 t\u1ea1o th\u00e0nh ch\u1ea5t chuy\u1ec3n ho\u00e1 c\u00f3 ho\u1ea1t t\u00ednh, ch\u1ea5t chuy\u1ec3n ho\u00e1 n\u00e0y \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc s\u1ef1 g\u1eafn k\u1ebft c\u1ee7a ADP v\u1edbi th\u1ee5 th\u1ec3 P2Y112 tr\u00ean ti\u1ec3u c\u1ea7u v\u00e0 \u1ee9c ch\u1ebf s\u1ef1 ho\u1ea1t ho\u00e1 c\u1ee7a ph\u1ee9c h\u1ee3p glycoprotein GP IIb\/IIIa do \u0111\u00f3 c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf s\u1ef1 k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u.<\/p>\n<p><em>Acid acetylsalicylic<\/em><\/p>\n<p>Acid acetylsalicylic \u1ee9c ch\u1ebf kh\u00f4ng \u0111\u1ea3o ng\u01b0\u1ee3c c\u1ee7a prostaglandin COX v\u00e0 \u1ee9c ch\u1ebf s\u1ea3n sinh thromboxan A2 (ch\u1ea5t g\u00e2y co m\u1ea1ch, k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u), t\u1eeb \u0111\u00f3 \u1ee9c ch\u1ebf k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p><em>Clopidogrel<\/em><\/p>\n<ul>\n<li>Clopidogrel \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh sau khi u\u1ed1ng, v\u1edbi sinh kh\u1ea3 d\u1ee5ng \u00edt nh\u1ea5t 50% v\u00e0 n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh \u0111\u1ea1t sau kho\u1ea3ng 45 ph\u00fat.<\/li>\n<li>Thu\u1ed1c chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu \u1edf gan qua esterase v\u00e0 cytochrome P450, t\u1ea1o ra ch\u1ea5t chuy\u1ec3n h\u00f3a thiol c\u00f3 ho\u1ea1t t\u00ednh, \u1ee9c ch\u1ebf k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u kh\u00f4ng h\u1ed3i ph\u1ee5c.<\/li>\n<li>Kho\u1ea3ng 50% thu\u1ed1c th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u, 46% qua ph\u00e2n. Th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a clopidogrel l\u00e0 kho\u1ea3ng 6 gi\u1edd v\u00e0 c\u1ee7a ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00f4ng ho\u1ea1t t\u00ednh l\u00e0 8 gi\u1edd.<\/li>\n<\/ul>\n<p><em>Acid acetylsalicylic<\/em><\/p>\n<ul>\n<li>Acid acetylsalicylic \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh, th\u1ee7y gi\u1ea3i th\u00e0nh acid salicylic v\u00e0 \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong 1 gi\u1edd; bi\u1ebfn m\u1ea5t kh\u1ecfi huy\u1ebft t\u01b0\u01a1ng sau 1,5\u20133 gi\u1edd.<\/li>\n<li>Acid salicylic g\u1eafn m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng, ph\u00e2n b\u1ed1 r\u1ed9ng, chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu \u1edf gan th\u00e0nh c\u00e1c d\u1ea1ng li\u00ean h\u1ee3p.<\/li>\n<li>Th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 2\u20136 gi\u1edd, c\u00f3 th\u1ec3 k\u00e9o d\u00e0i khi d\u00f9ng li\u1ec1u cao. Th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua th\u1eadn, ph\u1ee5 thu\u1ed9c pH n\u01b0\u1edbc ti\u1ec3u.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Duoplavin 75mg\/100mg tr\u1ecb b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c Duoplavin 75mg\/100mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong ng\u0103n ng\u1eeba h\u00ecnh th\u00e0nh c\u1ee5c m\u00e1u \u0111\u00f4ng trong x\u01a1 c\u1ee9ng \u0111\u1ed9ng m\u1ea1ch, ng\u0103n ng\u1eeba c\u1ee5c m\u00e1u \u0111\u00f4ng g\u00e2y \u0111au th\u1eaft ng\u1ef1c kh\u00f4ng \u1ed5n \u0111\u1ecbnh, nh\u1ed3i m\u00e1u c\u01a1 tim.<\/p>\n<h2>Li\u1ec1u d\u00f9ng-C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Duoplavin 75mg\/100mg<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>U\u1ed1ng 1 vi\u00ean m\u1ed7i ng\u00e0y.<\/p>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p><strong>Duoplavin 75mg\/100mg u\u1ed1ng nh\u01b0 th\u1ebf n\u00e0o?<\/strong> U\u1ed1ng v\u1edbi n\u01b0\u1edbc, c\u00f3 th\u1ec3 u\u1ed1ng c\u00f9ng b\u1eefa \u0103n ho\u1eb7c kh\u00e1c b\u1eefa \u0103n.<\/p>\n<p>N\u00ean u\u1ed1ng v\u00e0o c\u00f9ng 1 khung gi\u1edd nh\u1ea5t \u0111\u1ecbnh m\u1ed7i ng\u00e0y.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Duoplavin 75mg\/100mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng Duoplavin 75mg\/100mg cho ng\u01b0\u1eddi m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o trong thu\u1ed1c.<\/li>\n<li>B\u1ec7nh gan n\u1eb7ng.<\/li>\n<li>B\u1ec7nh th\u1eadn n\u1eb7ng.<\/li>\n<li>Ph\u1ee5 n\u1eef mang thai 3 th\u00e1ng cu\u1ed1i thai k\u1ef3.<\/li>\n<li>\u0110ang ch\u1ea3y m\u00e1u trong n\u00e3o, lo\u00e9t d\u1ea1 d\u00e0y.<\/li>\n<li>D\u1ecb \u1ee9ng thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00f4ng steroid.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Duoplavin 75mg\/100mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>C\u1ea7n b\u00e1o tr\u01b0\u1edbc cho b\u00e1c s\u0129 tr\u01b0\u1edbc khi d\u00f9ng thu\u1ed1c n\u1ebfu b\u1ea1n c\u00f3 nguy c\u01a1 ch\u1ea3y m\u00e1u, c\u00f3 c\u1ee5c m\u00e1u \u0111\u00f4ng, b\u1ec7nh gan, b\u1ec7nh th\u1eadn, ti\u1ec1n s\u1eed hen suy\u1ec5n, d\u1ecb \u1ee9ng, b\u1ec7nh g\u00fat.<\/li>\n<li>Trong khi d\u00f9ng thu\u1ed1c c\u1ea7n b\u00e1o cho b\u00e1c s\u0129 n\u1ebfu b\u1ea1n c\u00f3 d\u1ef1 \u0111\u1ecbnh ph\u1eabu thu\u1eadt, m\u1eafc b\u1ec7nh ban xu\u1ea5t huy\u1ebft ti\u1ec3u c\u1ea7u huy\u1ebft kh\u1ed1i, v\u1ebft th\u01b0\u01a1ng ch\u1ea3y m\u00e1u.<\/li>\n<li>Kh\u00f4ng d\u00f9ng thu\u1ed1c cho tr\u1ebb d\u01b0\u1edbi 18 tu\u1ed5i.<\/li>\n<li>C\u00f3 th\u1ec3 x\u1ea3y ra h\u1ed9i ch\u1ee9ng Reye khi d\u00f9ng acid acetylsalicylic cho tr\u1ebb em nhi\u1ec5m si\u00eau vi. H\u1ed9i ch\u1ee9ng Reye l\u00e0 hi\u1ec7n t\u01b0\u1ee3ng hi\u1ebfm g\u1eb7p nh\u01b0ng c\u00f3 th\u1ec3 g\u00e2y ra t\u00ecnh tr\u1ea1ng t\u1eed vong.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5 Duoplavin 75mg\/100mg<\/h3>\n<p>M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o khi d\u00f9ng Duoplavin 75mg\/100mg bao g\u1ed3m \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, \u1ee3 n\u00f3ng, kh\u00f3 ti\u00eau, ch\u1ea3y m\u00e1u, lo\u00e9t d\u1ea1 d\u00e0y, bu\u1ed3n n\u00f4n, n\u00f4n m\u1eeda, t\u00e1o b\u00f3n, \u0111au \u0111\u1ea7u, cho\u00e1ng v\u00e1ng, cam gi\u00e1c ki\u1ebfn b\u00f2 ho\u1eb7c t\u00ea r\u1ea7n\u2026<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>C\u00f3 th\u1ec3 g\u00e2y \u1ea3nh h\u01b0\u1edfng khi d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c sau: thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng d\u1ea1ng u\u1ed1ng, heparin, omeprazole, vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p, b\u1ec7nh v\u1ea9y n\u1ebfn, thu\u1ed1c tr\u1ecb tr\u1ea7m c\u1ea3m, ticlopidin&#8230;<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng thu\u1ed1c Duoplavin 75mg\/100mg cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c Duoplavin 75mg\/100mg c\u00f3 th\u1ec3 g\u00e2y nh\u1ee9c \u0111\u1ea7u, cho\u00e1ng v\u00e1ng do \u0111\u00f3 th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>S\u1eed d\u1ee5ng qu\u00e1 li\u1ec1u Duoplavin 75mg\/100mg c\u00f3 nguy c\u01a1 cao t\u0103ng ch\u1ea3y m\u00e1u, c\u1ea7n \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf \u0111\u1ec3 ki\u1ec3m tra.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n Duoplavin 75mg\/100mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t, nhi\u1ec7t \u0111\u1ed9 kh\u00f4ng qu\u00e1 30 \u0111\u1ed9 C.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Duoplavin 75mg\/100mg nh\u01b0:<\/p>\n<p><a href=\"ihttps:\/\/vnras.com\/drug\/clopias\/\">Clopias<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH US Pharma USA \u2013 VI\u1ec6T NAM, d\u00f9ng \u0111\u1ec3 ph\u00f2ng ng\u1eeba huy\u1ebft kh\u1ed1i.<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/pfertzel\/\" data-mil=\"126597\">Pfertzel<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH US Pharma USA \u2013 VI\u1ec6T NAM, d\u00f9ng \u0111\u1ec3 d\u1ef1 ph\u00f2ng huy\u1ebft kh\u1ed1i.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Controversy in cardiology: clopidogrel or acetylsalicylic acid in the treatment of chronic coronary syndromes? truy c\u1eadp v\u00e0o ng\u00e0y 19 th\u00e1ng 08 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11110453\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11110453\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Duoplavin 75mg\/100mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong ng\u0103n ng\u1eeba h\u00ecnh th\u00e0nh c\u1ee5c m\u00e1u \u0111\u00f4ng trong x\u01a1 c\u1ee9ng \u0111\u1ed9ng m\u1ea1ch, ng\u0103n ng\u1eeba c\u1ee5c m\u00e1u \u0111\u00f4ng g\u00e2y \u0111au th\u1eaft ng\u1ef1c kh\u00f4ng \u1ed5n \u0111\u1ecbnh, nh\u1ed3i m\u00e1u c\u01a1 tim.<\/p>\n","protected":false},"author":1,"featured_media":133465,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-133417","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/133417","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=133417"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/133465"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=133417"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=133417"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=133417"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}