{"id":131604,"date":"2025-08-09T16:59:09","date_gmt":"2025-08-09T09:59:09","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=131604"},"modified":"2025-08-09T17:42:18","modified_gmt":"2025-08-09T10:42:18","slug":"clopidogrel-75-mv","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/clopidogrel-75-mv\/","title":{"rendered":"Clopidogrel 75-MV"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m Clopidogrel 75-MV v\u1edbi t\u00e1c d\u1ee5ng d\u1ef1 ph\u00f2ng th\u1ee9 ph\u00e1t c\u00e1c bi\u1ebfn c\u1ed1 huy\u1ebft kh\u1ed1i do x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch v\u00e0 t\u1eafc m\u1ea1ch do huy\u1ebft kh\u1ed1i trong rung nh\u0129 \u1edf ng\u01b0\u1eddi l\u1edbn, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n US Pharma USA.<\/strong><\/p>\n<h2>Clopidogrel 75-MV l\u00e0 s\u1ea3n ph\u1ea9m g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean Clopidogrel 75-MV\u00a0c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li>Clopidogrel (d\u01b0\u1edbi d\u1ea1ng Clopidogrel bisulfat) 75mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<ul>\n<li>S\u0110K : 893110562824<\/li>\n<li>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i : H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/li>\n<li>Xu\u1ea5t x\u1ee9 : Vi\u1ec7t Nam<\/li>\n<\/ul>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a Clopidogrel 75-MV<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Sau khi h\u1ea5p th\u1ee5, clopidogrel (kh\u00f4ng ho\u1ea1t t\u00ednh) \u0111\u01b0\u1ee3c oxy h\u00f3a th\u00e0nh 2-oxo clopidogrel (kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh) b\u1edfi c\u00e1c enzyme cytochrome P450 (CYP) trong gan. Sau \u0111\u00f3, 2-oxo clopidogrel \u0111\u01b0\u1ee3c chuy\u1ec3n th\u00e0nh c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a thiol ho\u1ea1t \u0111\u1ed9ng.<\/p>\n<p>Ch\u1ea5t chuy\u1ec3n h\u00f3a ho\u1ea1t \u0111\u1ed9ng sau \u0111\u00f3 \u0111\u01b0\u1ee3c v\u1eadn chuy\u1ec3n v\u00e0o tu\u1ea7n ho\u00e0n m\u00e1u, t\u1ea1i \u0111\u00f3 n\u00f3 li\u00ean k\u1ebft v\u1edbi th\u1ee5 th\u1ec3 adenosine diphosphate (ADP) tr\u00ean b\u1ec1 m\u1eb7t ti\u1ec3u c\u1ea7u, ng\u0103n ch\u1eb7n s\u1ef1 ho\u1ea1t h\u00f3a c\u1ee7a con \u0111\u01b0\u1eddng glycoprotein IIb\/IIIa v\u00e0 do \u0111\u00f3, l\u00e0m gi\u1ea3m k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u<\/p>\n<p>Do \u0111\u00f3, clopidogrel c\u00f3 \u0111\u1eb7c t\u00ednh ch\u1ed1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u.<\/p>\n<h3>D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu : Thu\u1ed1c \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh sau khi u\u1ed1ng. Sinh kh\u1ea3 d\u1ee5ng kho\u1ea3ng 50%.<\/p>\n<p>Ph\u00e2n b\u1ed1 : Clopidogrel \u0111\u01b0\u1ee3c ph\u00e2n b\u1ed1 nhanh ch\u00f3ng trong c\u01a1 th\u1ec3, \u0111\u1eb7c bi\u1ec7t l\u00e0 ti\u1ec3u c\u1ea7u v\u00e0 c\u00e1c m\u00f4, thu\u1ed1c li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (kho\u1ea3ng 98%)<\/p>\n<p>Chuy\u1ec3n h\u00f3a : \u1ede gan, kho\u1ea3ng 15% clopidogrel \u0111\u01b0\u1ee3c h\u1ea5p th\u1ee5 \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a b\u1edfi h\u1ec7 th\u1ed1ng cytochrome P450 (CYP) \u0111\u1ec3 t\u1ea1o ra ch\u1ea5t chuy\u1ec3n h\u00f3a ho\u1ea1t \u0111\u1ed9ng c\u1ee7a n\u00f3 th\u00f4ng qua qu\u00e1 tr\u00ecnh ho\u1ea1t h\u00f3a sinh h\u1ecdc 2 b\u01b0\u1edbc, trong khi 85% c\u00f2n l\u1ea1i \u0111\u01b0\u1ee3c th\u1ee7y ph\u00e2n b\u1edfi carboxylesterase 1 (CES1) th\u00e0nh d\u1eabn xu\u1ea5t axit cacboxylic kh\u00f4ng ho\u1ea1t \u0111\u1ed9ng.<\/p>\n<p>Th\u1ea3i tr\u1eeb : Th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 6 gi\u1edd, \u0111\u00e0o th\u1ea3i ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u.<\/p>\n<h2>Ch\u1ec9 \u0111\u1ecbnh c\u1ee7a s\u1ea3n ph\u1ea9m Clopidogrel 75-MV?<\/h2>\n<p>Clopidogrel 75-MV \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho ng\u01b0\u1eddi l\u1edbn trong tr\u01b0\u1eddng h\u1ee3p :<\/p>\n<p>D\u1ef1 ph\u00f2ng th\u1ee9 ph\u00e1t c\u00e1c bi\u1ebfn c\u1ed1 huy\u1ebft kh\u1ed1i do x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch :<\/p>\n<ul>\n<li>Sau nh\u1ed3i m\u00e1u c\u01a1 tim, \u0111\u1ed9t qu\u1ef5 do thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9.<\/li>\n<li>B\u1ec7nh l\u00fd \u0111\u1ed9ng m\u1ea1ch ngo\u1ea1i bi\u00ean<\/li>\n<li>H\u1ed9i ch\u1ee9ng m\u1ea1ch v\u00e0nh c\u1ea5p t\u00ednh<\/li>\n<\/ul>\n<p>D\u1ef1 ph\u00f2ng c\u00e1c bi\u1ebfn c\u1ed1 x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch v\u00e0 t\u1eafc m\u1ea1ch do huy\u1ebft kh\u1ed1i trong rung nh\u0129 trong tr\u01b0\u1eddng h\u1ee3p kh\u00f4ng th\u00edch h\u1ee3p d\u00f9ng thu\u1ed1c kh\u00e1ng vitamin K ho\u1eb7c nguy c\u01a1 xu\u1ea5t huy\u1ebft th\u1ea5p.<\/p>\n<figure id=\"attachment_131605\" aria-describedby=\"caption-attachment-131605\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-131605\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/clopidogrel-75-mv-du-phong-bien-co-huyet-khoi.jpg\" alt=\"Clopidogrel 75-MV d\u1ef1 ph\u00f2ng bi\u1ebfn c\u1ed1 huy\u1ebft kh\u1ed1i\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/clopidogrel-75-mv-du-phong-bien-co-huyet-khoi.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/clopidogrel-75-mv-du-phong-bien-co-huyet-khoi-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/clopidogrel-75-mv-du-phong-bien-co-huyet-khoi-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/clopidogrel-75-mv-du-phong-bien-co-huyet-khoi-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-131605\" class=\"wp-caption-text\">Clopidogrel 75-MV d\u1ef1 ph\u00f2ng bi\u1ebfn c\u1ed1 huy\u1ebft kh\u1ed1i<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a Clopidogrel 75-MV<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Li\u1ec1u khuy\u1ebfn c\u00e1o : 1 vi\u00ean\/l\u1ea7n\/ng\u00e0y.<\/p>\n<p>H\u1ed9i ch\u1ee9ng m\u1ea1ch v\u00e0nh c\u1ea5p:<\/p>\n<ul>\n<li>Kh\u00f4ng c\u00f3 ST ch\u00eanh l\u00ean: Kh\u1edfi \u0111\u1ea7u: 4-8 vi\u00ean\/1 l\u1ea7n, d\u00f9ng 1 l\u1ea7n\/ng\u00e0y. Li\u1ec1u duy tr\u00ec: 1 vi\u00ean\/l\u1ea7n\/ng\u00e0y.<\/li>\n<li>Nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p c\u00f3 ST ch\u00eanh l\u00ean: Kh\u1edfi \u0111\u1ea7u: 4 vi\u00ean. Li\u1ec1u duy tr\u00ec: 1 vi\u00ean\/l\u1ea7n\/ng\u00e0y.<\/li>\n<\/ul>\n<p>Ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 \u0111\u1ed9t qu\u1ef5 t\u1eeb v\u1eeba \u0111\u1ebfn cao: Kh\u1edfi \u0111\u1ea7u: 4 vi\u00ean. Li\u1ec1u duy tr\u00ec duy tr\u00ec: 1 vi\u00ean\/l\u1ea7n\/ng\u00e0y. \u0110i\u1ec1u tr\u1ecb trong 21 ng\u00e0y sau c\u01a1n \u0111\u1ed9t qu\u1ef5.<\/p>\n<p>Rung nh\u0129: 1 vi\u00ean\/l\u1ea7n\/ng\u00e0y.<\/p>\n<h3>C\u00e1ch d\u00f9ng<\/h3>\n<p>U\u1ed1ng c\u00f9ng n\u01b0\u1edbc l\u1ecdc c\u00f9ng ho\u1eb7c ngo\u00e0i b\u1eefa \u0103n.<\/p>\n<h2>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh c\u1ee7a Clopidogrel 75-MV<\/h2>\n<p>Kh\u00f4ng d\u00f9ng <strong>Thu\u1ed1c tim m\u1ea1ch Clopidogrel 75-MV<\/strong> trong tr\u01b0\u1eddng h\u1ee3p b\u1ecb m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>B\u1ec7nh nh\u00e2n suy gan n\u1eb7ng, xu\u1ea5t huy\u1ebft n\u1ed9i s\u1ecd, lo\u00e9t d\u1ea1 d\u00e0y-t\u00e1 tr\u00e0ng.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng Clopidogrel 75-MV<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>C\u1ea7n tham kh\u1ea3o \u00fd ki\u1ebfn b\u00e1c s\u0129 n\u1ebfu c\u00f3 ti\u1ec1n s\u1eed, \u0111ang m\u1eafc b\u1ec7nh l\u00fd ho\u1eb7c s\u1eed d\u1ee5ng thu\u1ed1c v\u00e0 c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c nh\u01b0 : suy gan, suy th\u1eadn.<\/p>\n<p>Ng\u1eebng clopidogrel \u00edt nh\u1ea5t 7 ng\u00e0y tr\u01b0\u1edbc khi ph\u1eabu thu\u1eadt n\u1ebfu kh\u00f4ng c\u1ea7n hi\u1ec7u qu\u1ea3 kh\u00e1ng ti\u1ec3u c\u1ea7u.<\/p>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng, c\u1ea7n ng\u1eebng thu\u1ed1c v\u00e0 theo d\u00f5i \u0111i\u1ec1u tr\u1ecb chuy\u00ean khoa n\u1ebfu xu\u1ea5t hi\u1ec7n tri\u1ec7u ch\u1ee9ng.<\/p>\n<p>\u0110\u1ec3 xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Th\u01b0\u1eddng g\u1eb7p: xu\u1ea5t huy\u1ebft ti\u00eau h\u00f3a, ti\u00eau ch\u1ea3y, ti\u1ec3u ra m\u00e1u, bu\u1ed3n n\u00f4n, ng\u1ee9a<\/p>\n<p>Nghi\u00eam tr\u1ecdng: b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng c\u00e1c thu\u1ed1c aspirin, Heparin, thu\u1ed1c tan huy\u1ebft kh\u1ed1i, NSAIDs do t\u0103ng nguy c\u01a1 xu\u1ea5t huy\u1ebft ti\u00eau h\u00f3a.<\/p>\n<p>Kh\u00f4ng d\u00f9ng c\u00f9ng wafarin do t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u.<\/p>\n<p>Clopidogrel 75-MV l\u00e0m gi\u1ea3m chuy\u1ec3n h\u00f3a thu\u1ed1c c\u1ea3m \u1ee9ng enzzyme cytochrom P450 CYP2C19.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Kh\u00f4ng n\u00ean d\u00f9ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa. H\u1ecfi \u00fd ki\u1ebfn b\u00e1c s\u0129 tr\u01b0\u1edbc khi d\u00f9ng.<\/p>\n<h3>Qu\u00e1 li\u1ec1u<\/h3>\n<p>B\u00e1o ngay cho c\u1edf s\u1edf y t\u1ebf g\u1ea7n nh\u1ea5t \u0111\u1ec3 ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb k\u1ecbp th\u1eddi : r\u1eeda d\u1ea1 d\u00e0y.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n n\u01a1i kh\u00f4 tho\u00e1ng, m\u00e1t, tr\u00e1nh \u00e1nh n\u1eafng tr\u1ef1c ti\u1ebfp.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng v\u1edbi nh\u01b0:<\/p>\n<ul>\n<li><a href=\"https:\/\/vnras.com\/drug\/fidorel-tab-75mg\/\">Thu\u1ed1c Fidorel Tab. 75mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Daewon Pharm \u2013 H\u00e0n Qu\u1ed1c. Th\u00e0nh ph\u1ea7n ch\u00ednh trong thu\u1ed1c l\u00e0 Clopidogrel h\u00e0m l\u01b0\u1ee3ng 75mg, gi\u00fap \u0111i\u1ec1u tr\u1ecb v\u00e0 ph\u00f2ng ng\u1eeba bi\u1ebfn c\u1ed1 huy\u1ebft kh\u1ed1i do x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch.<\/li>\n<li><a href=\"https:\/\/vnras.com\/drug\/bilgrel-75mg\/\">Thu\u1ed1c Bilgrel 75mg<\/a> \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 ng\u0103n ng\u1eeba v\u00e0 \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh li\u00ean quan \u0111\u1ebfn m\u1ea1ch m\u00e1u b\u1ecb t\u1eafc ngh\u1ebdn, bao g\u1ed3m h\u1ed9i ch\u1ee9ng v\u00e0nh c\u1ea5p, \u0111\u1ed9t qu\u1ef5, b\u1ec7nh \u0111\u1ed9ng m\u1ea1ch ngo\u1ea1i bi\u00ean<\/li>\n<\/ul>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Mohammed Jarrar, Shalini Behl, Ganiraju Manyam, Hany Ganah, Mohammed Nazir, Reem Nasab, Khaled Moustafa (2015), Cytochrome allelic variants and clopidogrel metabolismin cardiovascular diseases therapy. Truy c\u1eadp ng\u00e0y 26\/05\/2025 t\u1eeb <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s11033-016-3983-1\" rel=\"noopener\">https:\/\/link.springer.com\/article\/10.1007\/s11033-016-3983-1<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Clopidogrel 75-MV \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh d\u1ef1 ph\u00f2ng th\u1ee9 ph\u00e1t c\u00e1c bi\u1ebfn c\u1ed1 huy\u1ebft kh\u1ed1i do x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch v\u00e0 t\u1eafc m\u1ea1ch do huy\u1ebft kh\u1ed1i trong rung nh\u0129 \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh.<\/p>\n","protected":false},"author":1,"featured_media":131606,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-131604","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/131604","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=131604"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/131606"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=131604"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=131604"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=131604"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}