{"id":131514,"date":"2025-08-09T01:25:53","date_gmt":"2025-08-08T18:25:53","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=131514"},"modified":"2025-08-09T01:33:01","modified_gmt":"2025-08-08T18:33:01","slug":"crestor-10mg-astrazeneca","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/crestor-10mg-astrazeneca\/","title":{"rendered":"Crestor 10mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <a href=\"https:\/\/vnras.com\/drug\/\">d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Crestor 10mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi IPR Pharmaceuticals Inc. c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-18150-14<\/strong><\/p>\n<h2>Crestor 10mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ng Crestor 10mg<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t: Rosuvastatin 10 mg (d\u01b0\u1edbi d\u1ea1ng rosuvastatin calci).<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c nh\u00e2n: Lactose monohydrat, cellulose vi tinh th\u1ec3, calci phosphat, crospovidon, magnesi stearat.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c bao phim: Lactose monohydrat, hypromellose, glycerol triacetat, titan dioxyd (E171), s\u1eaft oxyd v\u00e0ng\/\u0111\u1ecf (E172<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-18150-14<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 2 v\u1ec9 x 14 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Hoa K\u1ef3<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Crestor 10mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Rosuvastatin l\u00e0 ho\u1ea1t ch\u1ea5t thu\u1ed9c nh\u00f3m \u1ee9c ch\u1ebf HMG-CoA reductase, c\u00f3 t\u00e1c d\u1ee5ng ch\u1ecdn l\u1ecdc v\u00e0 c\u1ea1nh tranh v\u1edbi enzym n\u00e0y. Enzym HMG-CoA reductase tham gia v\u00e0o b\u01b0\u1edbc chuy\u1ec3n \u0111\u1ed5i 3-hydroxy-3-methylglutaryl coenzym A th\u00e0nh mevalonat \u2013 ti\u1ec1n ch\u1ea5t quan tr\u1ecdng trong qu\u00e1 tr\u00ecnh h\u00ecnh th\u00e0nh cholesterol. T\u00e1c d\u1ee5ng ch\u1ee7 y\u1ebfu di\u1ec5n ra \u1edf gan, n\u01a1i rosuvastatin l\u00e0m t\u0103ng s\u1ed1 l\u01b0\u1ee3ng th\u1ee5 th\u1ec3 LDL tr\u00ean b\u1ec1 m\u1eb7t t\u1ebf b\u00e0o gan, t\u1eeb \u0111\u00f3 th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh thu nh\u1eadn v\u00e0 ph\u00e2n gi\u1ea3i LDL, \u0111\u1ed3ng th\u1eddi \u1ee9c ch\u1ebf h\u00ecnh th\u00e0nh VLDL, gi\u00fap gi\u1ea3m n\u1ed3ng \u0111\u1ed9 LDL v\u00e0 VLDL trong m\u00e1u.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Sau khi u\u1ed1ng, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng th\u01b0\u1eddng \u0111\u1ea1t sau kho\u1ea3ng 5 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i v\u00e0o kho\u1ea3ng 20%.<\/p>\n<p>Ph\u00e2n b\u1ed1: Ph\u00e2n b\u1ed1 nhi\u1ec1u t\u1ea1i gan \u2013 c\u01a1 quan t\u1ed5ng h\u1ee3p cholesterol ch\u00ednh. Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 trung b\u00ecnh kho\u1ea3ng 134 l\u00edt. T\u1ef7 l\u1ec7 g\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 90%, ch\u1ee7 y\u1ebfu v\u1edbi albumin.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Rosuvastatin chuy\u1ec3n h\u00f3a \u1edf m\u1ee9c th\u1ea5p (x\u1ea5p x\u1ec9 10%). Nghi\u00ean c\u1ee9u in vitro cho th\u1ea5y CYP2C9 l\u00e0 enzym ch\u00ednh tham gia chuy\u1ec3n h\u00f3a, c\u00e1c CYP3A4 v\u00e0 CYP2D6 \u0111\u00f3ng vai tr\u00f2 nh\u1ecf h\u01a1n. Hai ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh l\u00e0 N-desmethyl (ho\u1ea1t t\u00ednh y\u1ebfu h\u01a1n kho\u1ea3ng 50%) v\u00e0 d\u1ea1ng lacton (kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh l\u00e2m s\u00e0ng). Rosuvastatin t\u1ed3n t\u1ea1i \u1edf d\u1ea1ng nguy\u00ean v\u1eb9n chi\u1ebfm h\u01a1n 90% kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf HMG-CoA reductase trong m\u00e1u.<\/p>\n<p>Th\u1ea3i tr\u1eeb: Kho\u1ea3ng 90% li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua ph\u00e2n, ph\u1ea7n l\u1edbn \u1edf d\u1ea1ng nguy\u00ean v\u1eb9n; kho\u1ea3ng 5% th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i. Th\u1eddi gian b\u00e1n th\u1ea3i trung b\u00ecnh kho\u1ea3ng 19 gi\u1edd, kh\u00f4ng k\u00e9o d\u00e0i khi t\u0103ng li\u1ec1u. \u0110\u1ed9 thanh th\u1ea3i huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 50 L\/gi\u1edd. Ho\u1ea1t ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c v\u1eadn chuy\u1ec3n qua gan nh\u1edd ch\u1ea5t v\u1eadn chuy\u1ec3n OATP-C, y\u1ebfu t\u1ed1 quan tr\u1ecdng trong qu\u00e1 tr\u00ecnh th\u1ea3i tr\u1eeb.<\/p>\n<h2>Thu\u1ed1c Crestor 10mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>T\u0103ng cholesterol m\u00e1u nguy\u00ean ph\u00e1t (lo\u1ea1i IIa, k\u1ec3 c\u1ea3 t\u0103ng cholesterol m\u00e1u gia \u0111\u00ecnh ki\u1ec3u d\u1ecb h\u1ee3p t\u1eed) ho\u1eb7c r\u1ed1i lo\u1ea1n lipid m\u00e1u h\u1ed7n h\u1ee3p (lo\u1ea1i IIb) khi ch\u1ebf \u0111\u1ed9 \u0103n v\u00e0 c\u00e1c bi\u1ec7n ph\u00e1p kh\u00f4ng d\u00f9ng thu\u1ed1c kh\u00f4ng \u0111\u1ea1t hi\u1ec7u qu\u1ea3 mong mu\u1ed1n.<\/p>\n<p>T\u0103ng lipoprotein m\u00e1u typ III (r\u1ed1i lo\u1ea1n beta-lipoprotein m\u00e1u nguy\u00ean ph\u00e1t) \u2013 d\u00f9ng k\u1ebft h\u1ee3p ch\u1ebf \u0111\u1ed9 \u0103n \u0111\u1ec3 c\u1ea3i thi\u1ec7n n\u1ed3ng \u0111\u1ed9 lipid.<\/p>\n<p>T\u0103ng triglycerid \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh.<\/p>\n<p>T\u0103ng cholesterol m\u00e1u gia \u0111\u00ecnh ki\u1ec3u \u0111\u1ed3ng h\u1ee3p t\u1eed \u1edf b\u1ec7nh nhi t\u1eeb 7 \u2013 17 tu\u1ed5i v\u00e0 ng\u01b0\u1eddi l\u1edbn \u2013 h\u1ed7 tr\u1ee3 ch\u1ebf \u0111\u1ed9 \u0103n ho\u1eb7c ph\u1ed1i h\u1ee3p c\u00e1c li\u1ec7u ph\u00e1p kh\u00e1c nh\u01b0 g\u1ea1n t\u00e1ch LDL khi c\u1ea7n.<\/p>\n<p>T\u0103ng cholesterol m\u00e1u gia \u0111\u00ecnh ki\u1ec3u d\u1ecb h\u1ee3p t\u1eed \u1edf tr\u1ebb t\u1eeb 8 \u2013 17 tu\u1ed5i \u2013 h\u1ed7 tr\u1ee3 gi\u1ea3m cholesterol to\u00e0n ph\u1ea7n, LDL-C v\u00e0 ApoB khi ch\u1ec9 \u0103n ki\u00eang kh\u00f4ng \u0111\u1ea1t m\u1ee5c ti\u00eau.<\/p>\n<p>L\u00e0m ch\u1eadm ti\u1ebfn tri\u1ec3n x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh khi k\u1ebft h\u1ee3p ch\u1ebf \u0111\u1ed9 \u0103n v\u00e0 \u0111i\u1ec1u tr\u1ecb h\u1ea1 lipid \u0111\u1ec3 \u0111\u1ea1t m\u1ee9c LDL-C m\u1ee5c ti\u00eau.<\/p>\n<p>D\u1ef1 ph\u00f2ng ti\u00ean ph\u00e1t bi\u1ebfn c\u1ed1 tim m\u1ea1ch \u1edf ng\u01b0\u1eddi kh\u00f4ng c\u00f3 b\u1ec7nh m\u1ea1ch v\u00e0nh nh\u01b0ng c\u00f3 nguy c\u01a1 cao (nam \u226550 tu\u1ed5i, n\u1eef \u226560 tu\u1ed5i) k\u00e8m hsCRP \u22652 mg\/L v\u00e0 \u00edt nh\u1ea5t 1 y\u1ebfu t\u1ed1 nguy c\u01a1 nh\u01b0 t\u0103ng huy\u1ebft \u00e1p, HDL-C th\u1ea5p, h\u00fat thu\u1ed1c ho\u1eb7c ti\u1ec1n s\u1eed gia \u0111\u00ecnh m\u1eafc b\u1ec7nh tim s\u1edbm.<\/p>\n<figure id=\"attachment_131527\" aria-describedby=\"caption-attachment-131527\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-131527\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Crestor-10mg-AstraZeneca.jpg\" alt=\"Crestor 10mg\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Crestor-10mg-AstraZeneca.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Crestor-10mg-AstraZeneca-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Crestor-10mg-AstraZeneca-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Crestor-10mg-AstraZeneca-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-131527\" class=\"wp-caption-text\">Thu\u1ed1c Crestor 10mg gi\u1ea3m cholesterol to\u00e0n ph\u1ea7n, LDL-C, triglycerid v\u00e0 t\u0103ng HDL-C, h\u1ed7 tr\u1ee3 ph\u00f2ng ng\u1eeba c\u00e1c bi\u1ebfn c\u1ed1 tim m\u1ea1ch nguy\u00ean ph\u00e1t \u1edf ng\u01b0\u1eddi c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1.<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Ng\u01b0\u1eddi l\u1edbn: Kh\u1edfi \u0111\u1ea7u 5\u201310 mg\/ng\u00e0y, u\u1ed1ng 1 l\u1ea7n. \u0110i\u1ec1u ch\u1ec9nh li\u1ec1u sau \u00edt nh\u1ea5t 4 tu\u1ea7n t\u00f9y \u0111\u00e1p \u1ee9ng, t\u1ed1i \u0111a 20 mg\/ng\u00e0y. Li\u1ec1u 40 mg ch\u1ec9 \u00e1p d\u1ee5ng cho t\u0103ng cholesterol m\u00e1u n\u1eb7ng c\u00f3 nguy c\u01a1 tim m\u1ea1ch r\u1ea5t cao v\u00e0 c\u1ea7n theo d\u00f5i s\u00e1t.<\/p>\n<p>D\u1ef1 ph\u00f2ng bi\u1ebfn c\u1ed1 tim m\u1ea1ch: 20 mg\/ng\u00e0y.<\/p>\n<p>Tr\u1ebb 8 \u2013 &lt;10 tu\u1ed5i b\u1ecb t\u0103ng cholesterol m\u00e1u gia \u0111\u00ecnh d\u1ecb h\u1ee3p t\u1eed: 5\u201310 mg\/ng\u00e0y.<\/p>\n<p>Tr\u1ebb 10 \u2013 17 tu\u1ed5i b\u1ecb t\u0103ng cholesterol m\u00e1u gia \u0111\u00ecnh d\u1ecb h\u1ee3p t\u1eed: 5\u201320 mg\/ng\u00e0y.<\/p>\n<p>Tr\u1ebb 7 \u2013 17 tu\u1ed5i b\u1ecb t\u0103ng cholesterol m\u00e1u gia \u0111\u00ecnh \u0111\u1ed3ng h\u1ee3p t\u1eed: 20 mg\/ng\u00e0y.<\/p>\n<p>Ng\u01b0\u1eddi \u226570 tu\u1ed5i: Kh\u1edfi \u0111\u1ea7u 5 mg\/ng\u00e0y.<\/p>\n<p>Suy th\u1eadn nh\u1eb9 \u2013 trung b\u00ecnh: Kh\u00f4ng c\u1ea7n ch\u1ec9nh li\u1ec1u \u1edf m\u1ee9c nh\u1eb9; kh\u1edfi \u0111\u1ea7u 5 mg\/ng\u00e0y \u1edf m\u1ee9c trung b\u00ecnh; ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh li\u1ec1u 40 mg.<\/p>\n<p>Suy gan m\u1ee9c Child-Pugh \u22647: Kh\u00f4ng ch\u1ec9nh li\u1ec1u; Child-Pugh 8\u20139 c\u1ea7n theo d\u00f5i; ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh n\u1ebfu b\u1ec7nh gan ti\u1ebfn tri\u1ec3n.<\/p>\n<p>Ng\u01b0\u1eddi ch\u00e2u \u00c1: C\u00e2n nh\u1eafc kh\u1edfi \u0111\u1ea7u 5 mg\/ng\u00e0y do n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00e1u cao h\u01a1n.<\/p>\n<p>D\u00f9ng chung gemfibrozil ho\u1eb7c thu\u1ed1c \u1ee9c ch\u1ebf protease: Kh\u00f4ng v\u01b0\u1ee3t qu\u00e1 10 mg\/ng\u00e0y, kh\u1edfi \u0111\u1ea7u 5 mg\/ng\u00e0y.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>U\u1ed1ng nguy\u00ean vi\u00ean Crestor 10mg, c\u00f3 th\u1ec3 d\u00f9ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng b\u1eefa \u0103n, v\u00e0o b\u1ea5t k\u1ef3 th\u1eddi \u0111i\u1ec3m n\u00e0o trong ng\u00e0y.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Crestor 10mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi rosuvastatin ho\u1eb7c b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c c\u00f3 trong <strong>vi\u00ean n\u00e9n Crestor 10mg<\/strong><\/p>\n<p>B\u1ec7nh gan ti\u1ebfn tri\u1ec3n ho\u1eb7c t\u0103ng transaminase k\u00e9o d\u00e0i kh\u00f4ng r\u00f5 nguy\u00ean nh\u00e2n (&gt;3 l\u1ea7n gi\u1edbi h\u1ea1n b\u00ecnh th\u01b0\u1eddng).<\/p>\n<p>Suy th\u1eadn n\u1eb7ng (\u0111\u1ed9 thanh th\u1ea3i creatinin &lt;30 ml\/ph\u00fat).<\/p>\n<p>B\u1ec7nh l\u00fd c\u01a1 ho\u1eb7c ti\u1ec1n s\u1eed ti\u00eau c\u01a1 v\u00e2n.<\/p>\n<p>\u0110ang d\u00f9ng cyclosporin.<\/p>\n<p>Ph\u1ee5 n\u1eef mang thai, cho con b\u00fa ho\u1eb7c ph\u1ee5 n\u1eef c\u00f3 kh\u1ea3 n\u0103ng mang thai nh\u01b0ng kh\u00f4ng \u00e1p d\u1ee5ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai hi\u1ec7u qu\u1ea3.<\/p>\n<p>Li\u1ec1u 40 mg ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf b\u1ec7nh nh\u00e2n c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1 ti\u00eau c\u01a1 v\u00e2n (suy th\u1eadn v\u1eeba, suy gi\u00e1p, ti\u1ec1n s\u1eed b\u1ec7nh c\u01a1, nghi\u1ec7n r\u01b0\u1ee3u, ng\u01b0\u1eddi ch\u00e2u \u00c1, d\u00f9ng ph\u1ed1i h\u1ee3p fibrat&#8230;).<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>C\u1ea7n theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn, nh\u1ea5t l\u00e0 khi d\u00f9ng li\u1ec1u 40 mg.<\/p>\n<p>\u0110o CK tr\u01b0\u1edbc khi d\u00f9ng \u1edf ng\u01b0\u1eddi c\u00f3 nguy c\u01a1, kh\u00f4ng b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb n\u1ebfu CK &gt;5 l\u1ea7n gi\u1edbi h\u1ea1n b\u00ecnh th\u01b0\u1eddng.<\/p>\n<p>N\u00ean duy tr\u00ec ch\u1ebf \u0111\u1ed9 \u0103n \u00edt cholesterol trong su\u1ed1t qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>R\u1ed1i lo\u1ea1n m\u00e1u v\u00e0 mi\u1ec5n d\u1ecbch: Gi\u1ea3m ti\u1ec3u c\u1ea7u; ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn, ph\u00f9 m\u1ea1ch.<\/p>\n<p>N\u1ed9i ti\u1ebft: C\u00f3 th\u1ec3 kh\u1edfi ph\u00e1t \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1 (BMI &gt;30, triglycerid cao, ti\u1ec1n s\u1eed t\u0103ng huy\u1ebft \u00e1p, \u0111\u01b0\u1eddng huy\u1ebft l\u00fac \u0111\u00f3i \u2265 5,6 mmol\/L).<\/p>\n<p>T\u00e2m th\u1ea7n: Tr\u1ea7m c\u1ea3m.<\/p>\n<p>Th\u1ea7n kinh: Nh\u1ee9c \u0111\u1ea7u, ch\u00f3ng m\u1eb7t; b\u1ec7nh \u0111a d\u00e2y th\u1ea7n kinh, gi\u1ea3m tr\u00ed nh\u1edb; b\u1ec7nh l\u00fd th\u1ea7n kinh ngo\u1ea1i bi\u00ean, r\u1ed1i lo\u1ea1n gi\u1ea5c ng\u1ee7 (m\u1ea5t ng\u1ee7, \u00e1c m\u1ed9ng).<\/p>\n<p>H\u00f4 h\u1ea5p: Ho, kh\u00f3 th\u1edf.<\/p>\n<p>Ti\u00eau h\u00f3a: T\u00e1o b\u00f3n, bu\u1ed3n n\u00f4n, \u0111au b\u1ee5ng; vi\u00eam t\u1ee5y, ti\u00eau ch\u1ea3y.<\/p>\n<p>Gan m\u1eadt: T\u0103ng men gan; vi\u00eam gan, v\u00e0ng da.<\/p>\n<p>Da v\u00e0 m\u00f4 d\u01b0\u1edbi da: Ng\u1ee9a, ph\u00e1t ban, m\u1ec1 \u0111ay.<\/p>\n<p>C\u01a1 x\u01b0\u01a1ng kh\u1edbp: \u0110au c\u01a1, \u0111au kh\u1edbp, c\u0103ng c\u01a1; b\u1ec7nh c\u01a1, vi\u00eam c\u01a1, ti\u00eau c\u01a1 v\u00e2n; hi\u1ebfm g\u1eb7p h\u1ed9i ch\u1ee9ng Stevens-Johnson, ho\u1ea1i t\u1eed c\u01a1 do mi\u1ec5n d\u1ecbch, \u0111\u1ee9t g\u00e2n.<\/p>\n<p>Th\u1eadn \u2013 ti\u1ebft ni\u1ec7u: Ti\u1ec3u ra m\u00e1u, protein ni\u1ec7u (ch\u1ee7 y\u1ebfu c\u00f3 ngu\u1ed3n g\u1ed1c \u1ed1ng th\u1eadn, th\u01b0\u1eddng gi\u1ea3m ho\u1eb7c m\u1ea5t khi ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb).<\/p>\n<p>Kh\u00e1c: Suy nh\u01b0\u1ee3c; r\u1ed1i lo\u1ea1n t\u00ecnh d\u1ee5c; hi\u1ebfm g\u1eb7p vi\u00eam ph\u1ed5i m\u00f4 k\u1ebd khi d\u00f9ng l\u00e2u d\u00e0i.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Rosuvastatin l\u00e0 c\u01a1 ch\u1ea5t c\u1ee7a OATP1B1 v\u00e0 BCRP, d\u1ec5 t\u0103ng n\u1ed3ng \u0111\u1ed9 khi d\u00f9ng v\u1edbi thu\u1ed1c \u1ee9c ch\u1ebf c\u00e1c protein v\u1eadn chuy\u1ec3n n\u00e0y (gemfibrozil, thu\u1ed1c \u1ee9c ch\u1ebf protease, ciclosporin&#8230;). M\u1ed9t s\u1ed1 ph\u1ed1i h\u1ee3p c\u1ea7n gi\u1ea3m li\u1ec1u ho\u1eb7c tr\u00e1nh d\u00f9ng.<\/p>\n<p>Warfarin: C\u00f3 th\u1ec3 l\u00e0m t\u0103ng INR, c\u1ea7n theo d\u00f5i s\u00e1t khi b\u1eaft \u0111\u1ea7u, \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u ho\u1eb7c ng\u1eebng thu\u1ed1c.<\/p>\n<p>Thu\u1ed1c tr\u00e1nh thai d\u1ea1ng u\u1ed1ng\/HRT: D\u00f9ng c\u00f9ng Crestor l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 hormon sinh d\u1ee5c<\/p>\n<p>Kh\u00e1ng acid: D\u00f9ng \u0111\u1ed3ng th\u1eddi c\u00f3 th\u1ec3 gi\u1ea3m n\u1ed3ng \u0111\u1ed9 rosuvastatin; n\u00ean u\u1ed1ng c\u00e1ch nhau \u00edt nh\u1ea5t 2 gi\u1edd.<\/p>\n<p>Erythromycin: L\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 rosuvastatin, c\u00f3 th\u1ec3 do t\u0103ng nhu \u0111\u1ed9ng ru\u1ed9t.<\/p>\n<p>Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng chung Crestor 10mg AstraZeneca v\u1edbi acid fusidic, n\u1ebfu b\u1eaft bu\u1ed9c ph\u1ea3i d\u00f9ng c\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd d\u1ea5u hi\u1ec7u b\u1ec7nh c\u01a1.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Rosuvastatin ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh cho ph\u1ee5 n\u1eef \u0111ang mang thai ho\u1eb7c cho con b\u00fa. Cholesterol c\u00f3 l\u1ee3i cho s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a thai, d\u00f9ng Crestor ch\u1ee9a rosuvastatin g\u00e2y \u1ee9c ch\u1ebf HMG-CoA reductase c\u00f3 th\u1ec3 g\u00e2y h\u1ea1i cho b\u00e0o thai. N\u1ebfu ph\u00e1t hi\u1ec7n c\u00f3 thai trong qu\u00e1 tr\u00ecnh d\u00f9ng thu\u1ed1c, ph\u1ea3i ng\u1eebng \u0111i\u1ec1u tr\u1ecb ngay. \u1ede \u0111\u1ed9ng v\u1eadt, ho\u1ea1t ch\u1ea5t c\u00f3 b\u00e0i ti\u1ebft qua s\u1eefa; ch\u01b0a c\u00f3 d\u1eef li\u1ec7u \u1edf ng\u01b0\u1eddi, v\u00ec v\u1eady kh\u00f4ng n\u00ean d\u00f9ng khi \u0111ang cho con b\u00fa. Ph\u1ee5 n\u1eef trong \u0111\u1ed9 tu\u1ed5i sinh s\u1ea3n c\u1ea7n \u00e1p d\u1ee5ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai hi\u1ec7u qu\u1ea3 khi d\u00f9ng thu\u1ed1c.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u chuy\u00ean bi\u1ec7t \u0111\u00e1nh gi\u00e1 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y. Tuy nhi\u00ean, d\u1ef1a tr\u00ean c\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng, rosuvastatin \u00edt c\u00f3 kh\u1ea3 n\u0103ng \u1ea3nh h\u01b0\u1edfng. Ng\u01b0\u1eddi d\u00f9ng c\u1ea7n th\u1eadn tr\u1ecdng n\u1ebfu xu\u1ea5t hi\u1ec7n tri\u1ec7u ch\u1ee9ng nh\u01b0 ch\u00f3ng m\u1eb7t trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Hi\u1ec7n ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u cho Crestor 10mg. Khi qu\u00e1 li\u1ec1u, c\u1ea7n \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng k\u1ebft h\u1ee3p h\u1ed7 tr\u1ee3 y t\u1ebf ph\u00f9 h\u1ee3p, theo d\u00f5i ch\u1ee9c n\u0103ng gan v\u00e0 n\u1ed3ng \u0111\u1ed9 CK. Th\u1ea9m t\u00e1ch m\u00e1u c\u00f3 kh\u1ea3 n\u0103ng kh\u00f4ng mang l\u1ea1i l\u1ee3i \u00edch \u0111\u00e1ng k\u1ec3.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>Gi\u1eef Crestor 10mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/p>\n<p>Kh\u00f4ng \u0111\u1ec3 Crestor 10mg trong t\u1ea7m v\u1edbi tr\u1ebb em<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng Crestor 10mg khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Crestor 10mg nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/crestor\/\">Crestor 20mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Rosuvastatin, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi IPR Pharm Inc, \u0111i\u1ec1u tr\u1ecb t\u0103ng cholesterol m\u00e1u<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/ldnil-10\/\">Ldnil 10<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Rosuvastatin, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty MSN Laboratories Limited, \u0111i\u1ec1u tr\u1ecb t\u0103ng cholesterol m\u00e1u<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Crestor 10mg \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/To-huong-dan-su-dung-crestor-10mg-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>.<\/li>\n<li>Clearfield MB, Amerena J, Bassand JP, Hern\u00e1ndez Garc\u00eda HR, Miller SS, Sosef FF, Palmer MK, Bryzinski BS (2006). Comparison of the efficacy and safety of rosuvastatin 10 mg and atorvastatin 20 mg in high-risk patients with hypercholesterolemia&#8211;Prospective study to evaluate the Use of Low doses of the Statins Atorvastatin and Rosuvastatin (PULSAR). Trials. Truy c\u1eadp ng\u00e0y 9 th\u00e1ng 8 n\u0103m 2025 t\u1eeb:<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1779361\/\" rel=\"noopener\"> https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1779361\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p><span style=\"font-weight: 400;\">Thu\u1ed1c Crestor 10mg gi\u1ea3m cholesterol to\u00e0n ph\u1ea7n, LDL-C, triglycerid v\u00e0 t\u0103ng HDL-C, h\u1ed7 tr\u1ee3 ph\u00f2ng ng\u1eeba c\u00e1c bi\u1ebfn c\u1ed1 tim m\u1ea1ch nguy\u00ean ph\u00e1t \u1edf ng\u01b0\u1eddi c\u00f3 y\u1ebfu t\u1ed1 nguy c\u01a1.<\/span><\/p>\n","protected":false},"author":1,"featured_media":131516,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-131514","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/131514","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=131514"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/131516"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=131514"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=131514"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=131514"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}