{"id":130762,"date":"2025-08-05T11:31:08","date_gmt":"2025-08-05T04:31:08","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=130762"},"modified":"2025-08-05T16:11:55","modified_gmt":"2025-08-05T09:11:55","slug":"xelostad-20","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/xelostad-20\/","title":{"rendered":"Xelostad 20"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Xelostad 20 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean Doanh Stellapharm &#8211; chi nh\u00e1nh 1, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-35501-21.<\/strong><\/p>\n<h2>Xelostad 20 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong vi\u00ean n\u00e9n bao phim<strong> Xelostad 20<\/strong> c\u00f3 ch\u1ee9a ho\u1ea1t ch\u1ea5t ch\u00ednh <strong>Rivaroxaban<\/strong> 20mg v\u00e0 t\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VD-35501-21<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 v\u1ec9 x 14 vi\u00ean; H\u1ed9p 3 v\u1ec9 x 14 vi\u00ean; H\u1ed9p 8 v\u1ec9 x 14 vi\u00ean.<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_130766\" aria-describedby=\"caption-attachment-130766\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-130766\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Xelostad-20.jpg\" alt=\"Xelostad 20 d\u1ef1 ph\u00f2ng \u0111\u1ed9t qu\u1ef5 v\u00e0 thuy\u00ean t\u1eafc m\u1ea1ch to\u00e0n th\u00e2n\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Xelostad-20.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Xelostad-20-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Xelostad-20-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/08\/Xelostad-20-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-130766\" class=\"wp-caption-text\">Xelostad 20 d\u1ef1 ph\u00f2ng \u0111\u1ed9t qu\u1ef5 v\u00e0 thuy\u00ean t\u1eafc m\u1ea1ch to\u00e0n th\u00e2n<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Xelostad 20<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>\u0110\u1ec3 hi\u1ec3u t\u00e1c d\u1ee5ng c\u1ee7a Xelostad 20, c\u1ea7n n\u1eafm r\u00f5 v\u1ec1 con \u0111\u01b0\u1eddng \u0111\u00f4ng m\u00e1u. Qu\u00e1 tr\u00ecnh n\u00e0y l\u00e0 m\u1ed9t chu\u1ed7i ph\u1ea3n \u1ee9ng ph\u1ee9c t\u1ea1p, gi\u1ed1ng nh\u01b0 m\u1ed9t d\u00f2ng th\u00e1c, v\u1edbi s\u1ef1 tham gia c\u1ee7a nhi\u1ec1u y\u1ebfu t\u1ed1. Y\u1ebfu t\u1ed1 Xa (Factor Xa) \u0111\u00f3ng vai tr\u00f2 l\u00e0 m\u1ed9t \u0111i\u1ec3m h\u1ed9i t\u1ee5 then ch\u1ed1t, n\u01a1i c\u1ea3 hai con \u0111\u01b0\u1eddng \u0111\u00f4ng m\u00e1u n\u1ed9i sinh v\u00e0 ngo\u1ea1i sinh g\u1eb7p nhau. Khi \u0111\u01b0\u1ee3c ho\u1ea1t h\u00f3a, Y\u1ebfu t\u1ed1 Xa s\u1ebd chuy\u1ec3n Prothrombin th\u00e0nh Thrombin \u2013 enzyme trung t\u00e2m c\u00f3 kh\u1ea3 n\u0103ng chuy\u1ec3n Fibrinogen (d\u1ea1ng h\u00f2a tan) th\u00e0nh Fibrin (d\u1ea1ng s\u1ee3i kh\u00f4ng tan), t\u1ea1o th\u00e0nh m\u1ea1ng l\u01b0\u1edbi b\u1eaft gi\u1eef c\u00e1c t\u1ebf b\u00e0o m\u00e1u \u0111\u1ec3 h\u00ecnh th\u00e0nh c\u1ee5c m\u00e1u \u0111\u00f4ng (huy\u1ebft kh\u1ed1i).<\/p>\n<p>Rivaroxaban trong Xelostad 20 ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf tr\u1ef1c ti\u1ebfp, ch\u1ecdn l\u1ecdc v\u00e0 c\u00f3 h\u1ed3i ph\u1ee5c ngay t\u1ea1i v\u1ecb tr\u00ed ho\u1ea1t \u0111\u1ed9ng c\u1ee7a Y\u1ebfu t\u1ed1 Xa. B\u1eb1ng c\u00e1ch &#8220;kh\u00f3a&#8221; Y\u1ebfu t\u1ed1 Xa, Rivaroxaban ng\u0103n ch\u1eb7n hi\u1ec7u qu\u1ea3 qu\u00e1 tr\u00ecnh s\u1ea3n sinh Thrombin, t\u1eeb \u0111\u00f3 l\u00e0m gi\u00e1n \u0111o\u1ea1n s\u1ef1 h\u00ecnh th\u00e0nh v\u00e0 ph\u00e1t tri\u1ec3n c\u1ee7a c\u1ee5c m\u00e1u \u0111\u00f4ng. \u0110\u00e2y l\u00e0 m\u1ed9t c\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng ti\u00ean ti\u1ebfn, c\u00f3 t\u00ednh d\u1ef1 \u0111o\u00e1n cao v\u00e0 kh\u00f4ng c\u1ea7n theo d\u00f5i x\u00e9t nghi\u1ec7m \u0111\u00f4ng m\u00e1u th\u01b0\u1eddng quy nh\u01b0 c\u00e1c thu\u1ed1c kh\u00e1ng Vitamin K truy\u1ec1n th\u1ed1ng.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Rivaroxaban \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh ch\u00f3ng sau khi u\u1ed1ng. \u0110\u1ed1i v\u1edbi li\u1ec1u 20mg, sinh kh\u1ea3 d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng r\u1ea5t cao (80-100%) khi \u0111\u01b0\u1ee3c d\u00f9ng chung v\u1edbi b\u1eefa \u0103n. Th\u1ee9c \u0103n gi\u00fap t\u0103ng kh\u1ea3 n\u0103ng h\u1ea5p thu c\u1ee7a thu\u1ed1c m\u1ed9t c\u00e1ch \u0111\u00e1ng k\u1ec3.<\/p>\n<p>Ph\u00e2n b\u1ed1: Thu\u1ed1c li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (kho\u1ea3ng 92-95%), ch\u1ee7 y\u1ebfu l\u00e0 albumin.<\/p>\n<p>Chuy\u1ec3n h\u00f3a: Kho\u1ea3ng 2\/3 li\u1ec1u Rivaroxaban \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a qua gan, ch\u1ee7 y\u1ebfu th\u00f4ng qua h\u1ec7 enzyme Cytochrome P450 (CYP3A4, CYP2J2).<\/p>\n<p>Th\u1ea3i tr\u1eeb: Thu\u1ed1c \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua hai con \u0111\u01b0\u1eddng ch\u00ednh: kho\u1ea3ng 1\/3 li\u1ec1u \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb tr\u1ef1c ti\u1ebfp qua th\u1eadn d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i v\u00e0 2\/3 c\u00f2n l\u1ea1i \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb d\u01b0\u1edbi d\u1ea1ng ch\u1ea5t chuy\u1ec3n h\u00f3a (m\u1ed9t n\u1eeda qua th\u1eadn, m\u1ed9t n\u1eeda qua ph\u00e2n). Th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a thu\u1ed1c \u1edf ng\u01b0\u1eddi tr\u1ebb l\u00e0 5-9 gi\u1edd v\u00e0 \u1edf ng\u01b0\u1eddi cao tu\u1ed5i l\u00e0 11-13 gi\u1edd.<\/p>\n<h2>Thu\u1ed1c Xelostad 20 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Xelostad 20 \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p cho c\u00e1c ch\u1ec9 \u0111\u1ecbnh ch\u00ednh sau \u0111\u00e2y \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh:<\/p>\n<ul>\n<li>D\u1ef1 ph\u00f2ng \u0111\u1ed9t qu\u1ef5 v\u00e0 thuy\u00ean t\u1eafc m\u1ea1ch to\u00e0n th\u00e2n: D\u00e0nh cho b\u1ec7nh nh\u00e2n tr\u01b0\u1edfng th\u00e0nh b\u1ecb rung nh\u0129 kh\u00f4ng do b\u1ec7nh l\u00fd van tim (non-valvular atrial fibrillation) c\u00f3 m\u1ed9t ho\u1eb7c nhi\u1ec1u y\u1ebfu t\u1ed1 nguy c\u01a1 nh\u01b0: suy tim, t\u0103ng huy\u1ebft \u00e1p, t\u1eeb 75 tu\u1ed5i tr\u1edf l\u00ean, \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, ho\u1eb7c c\u00f3 ti\u1ec1n s\u1eed \u0111\u1ed9t qu\u1ef5.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb Huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u (DVT) v\u00e0 Thuy\u00ean t\u1eafc ph\u1ed5i (PE).<\/li>\n<li>D\u1ef1 ph\u00f2ng t\u00e1i ph\u00e1t DVT v\u00e0 PE.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Xelostad 20<\/h2>\n<p>D\u1ef1 ph\u00f2ng \u0111\u1ed9t qu\u1ef5 \u1edf b\u1ec7nh nh\u00e2n rung nh\u0129 (SPAF): 20mg (1 vi\u00ean), u\u1ed1ng 1 l\u1ea7n m\u1ed7i ng\u00e0y.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb DVT v\u00e0 PE c\u1ea5p t\u00ednh: 15mg, u\u1ed1ng 2 l\u1ea7n m\u1ed7i ng\u00e0y trong 3 tu\u1ea7n \u0111\u1ea7u ti\u00ean. Sau \u0111\u00f3, duy tr\u00ec v\u1edbi li\u1ec1u 20mg (1 vi\u00ean), u\u1ed1ng 1 l\u1ea7n m\u1ed7i ng\u00e0y.<\/p>\n<p>D\u1ef1 ph\u00f2ng t\u00e1i ph\u00e1t DVT v\u00e0 PE: Sau khi ho\u00e0n t\u1ea5t li\u1ec7u tr\u00ecnh \u0111i\u1ec1u tr\u1ecb (t\u1ed1i thi\u1ec3u 6 th\u00e1ng), b\u00e1c s\u0129 c\u00f3 th\u1ec3 c\u00e2n nh\u1eafc li\u1ec1u 20mg ho\u1eb7c 10mg, u\u1ed1ng 1 l\u1ea7n m\u1ed7i ng\u00e0y t\u00f9y thu\u1ed9c v\u00e0o nguy c\u01a1 t\u00e1i ph\u00e1t v\u00e0 nguy c\u01a1 ch\u1ea3y m\u00e1u c\u1ee7a t\u1eebng b\u1ec7nh nh\u00e2n.<\/p>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Xelostad 20<\/h2>\n<p>Vi\u00ean Xelostad 20mg (v\u00e0 c\u1ea3 vi\u00ean 15mg) ph\u1ea3i \u0111\u01b0\u1ee3c u\u1ed1ng c\u00f9ng v\u1edbi b\u1eefa \u0103n. vi\u1ec7c n\u00e0y \u0111\u1ea3m b\u1ea3o thu\u1ed1c \u0111\u01b0\u1ee3c h\u1ea5p thu t\u1ed1i \u0111a v\u00e0 \u0111\u1ea1t hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb cao nh\u1ea5t.<\/p>\n<p>\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n kh\u00f4ng th\u1ec3 nu\u1ed1t nguy\u00ean vi\u00ean, c\u00f3 th\u1ec3 nghi\u1ec1n vi\u00ean thu\u1ed1c v\u00e0 tr\u1ed9n v\u1edbi n\u01b0\u1edbc ho\u1eb7c th\u1ee9c \u0103n m\u1ec1m (nh\u01b0 ch\u00e1o, t\u00e1o nghi\u1ec1n) v\u00e0 d\u00f9ng ngay l\u1eadp t\u1ee9c.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Xelostad 20 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Qu\u00e1 m\u1eabn v\u1edbi Rivaroxaban ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>B\u1ec7nh nh\u00e2n \u0111ang c\u00f3 ch\u1ea3y m\u00e1u nghi\u00eam tr\u1ecdng tr\u00ean l\u00e2m s\u00e0ng (v\u00ed d\u1ee5: xu\u1ea5t huy\u1ebft n\u1ed9i s\u1ecd, xu\u1ea5t huy\u1ebft ti\u00eau h\u00f3a).<\/p>\n<p>B\u1ec7nh nh\u00e2n c\u00f3 t\u1ed5n th\u01b0\u01a1ng ho\u1eb7c b\u1ec7nh l\u00fd l\u00e0m t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u n\u1eb7ng (v\u00ed d\u1ee5: lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng \u0111ang ho\u1ea1t \u0111\u1ed9ng, u \u00e1c t\u00ednh c\u00f3 nguy c\u01a1 ch\u1ea3y m\u00e1u cao, ph\u1eabu thu\u1eadt n\u00e3o ho\u1eb7c m\u1eaft g\u1ea7n \u0111\u00e2y).<\/p>\n<p>\u0110ang \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng kh\u00e1c (nh\u01b0 Warfarin, Dabigatran, Apixaban, Heparin&#8230;) tr\u1eeb nh\u1eefng tr\u01b0\u1eddng h\u1ee3p \u0111\u1eb7c bi\u1ec7t khi chuy\u1ec3n \u0111\u1ed5i li\u1ec7u ph\u00e1p.<\/p>\n<p>B\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh gan c\u00f3 r\u1ed1i lo\u1ea1n \u0111\u00f4ng m\u00e1u v\u00e0 nguy c\u01a1 ch\u1ea3y m\u00e1u li\u00ean quan (bao g\u1ed3m c\u1ea3 b\u1ec7nh nh\u00e2n x\u01a1 gan Child-Pugh B v\u00e0 C).<\/p>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 \u0111ang cho con b\u00fa.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Xelostad 20<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Vi\u1ec7c d\u1eebng s\u1eed d\u1ee5ng Xelostad 20 \u0111\u1ed9t ng\u1ed9t m\u00e0 kh\u00f4ng c\u00f3 m\u1ed9t li\u1ec7u ph\u00e1p ch\u1ed1ng \u0111\u00f4ng thay th\u1ebf ph\u00f9 h\u1ee3p s\u1ebd l\u00e0m t\u0103ng \u0111\u00e1ng k\u1ec3 nguy c\u01a1 h\u00ecnh th\u00e0nh c\u1ee5c m\u00e1u \u0111\u00f4ng, d\u1eabn \u0111\u1ebfn c\u00e1c bi\u1ebfn c\u1ed1 nguy hi\u1ec3m nh\u01b0 \u0111\u1ed9t qu\u1ef5, nh\u1ed3i m\u00e1u c\u01a1 tim ho\u1eb7c thuy\u00ean t\u1eafc m\u1ea1ch. N\u1ebfu c\u1ea7n ph\u1ea3i ng\u01b0ng thu\u1ed1c, ph\u1ea3i th\u1ef1c hi\u1ec7n d\u01b0\u1edbi s\u1ef1 h\u01b0\u1edbng d\u1eabn c\u1ee7a b\u00e1c s\u0129.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Nguy c\u01a1 ch\u1ea3y m\u00e1u: \u0110\u00e2y l\u00e0 nguy c\u01a1 ch\u00ednh v\u00e0 c\u1ed1 h\u1eefu c\u1ee7a t\u1ea5t c\u1ea3 c\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng. B\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c theo d\u00f5i ch\u1eb7t ch\u1ebd c\u00e1c d\u1ea5u hi\u1ec7u v\u00e0 tri\u1ec7u ch\u1ee9ng c\u1ee7a ch\u1ea3y m\u00e1u (d\u1ec5 b\u1ea7m t\u00edm, ch\u1ea3y m\u00e1u ch\u00e2n r\u0103ng, ch\u1ea3y m\u00e1u cam, ti\u1ec3u ra m\u00e1u, ph\u00e2n \u0111en&#8230;).<\/p>\n<p>Ngo\u00e0i nguy c\u01a1 ch\u1ea3y m\u00e1u, c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n th\u01b0\u1eddng g\u1eb7p kh\u00e1c c\u00f3 th\u1ec3 bao g\u1ed3m: thi\u1ebfu m\u00e1u, ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, bu\u1ed3n n\u00f4n, \u0111au b\u1ee5ng, kh\u00f3 ti\u00eau, v\u00e0 t\u0103ng men gan.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Rivaroxaban \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a ch\u00ednh qua CYP3A4 v\u00e0 l\u00e0 c\u01a1 ch\u1ea5t c\u1ee7a P-glycoprotein (P-gp). Do \u0111\u00f3, c\u1ea7n h\u1ebft s\u1ee9c th\u1eadn tr\u1ecdng:<\/p>\n<ul>\n<li>Tr\u00e1nh d\u00f9ng chung v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf m\u1ea1nh \u0111\u1ed3ng th\u1eddi c\u1ea3 CYP3A4 v\u00e0 P-gp: Nh\u01b0 thu\u1ed1c kh\u00e1ng n\u1ea5m nh\u00f3m azole (ketoconazole, itraconazole) v\u00e0 thu\u1ed1c kh\u00e1ng virus HIV (ritonavir). C\u00e1c thu\u1ed1c n\u00e0y l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Rivaroxaban trong m\u00e1u, d\u1eabn \u0111\u1ebfn t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u.<\/li>\n<li>Tr\u00e1nh d\u00f9ng chung v\u1edbi c\u00e1c thu\u1ed1c c\u1ea3m \u1ee9ng m\u1ea1nh \u0111\u1ed3ng th\u1eddi c\u1ea3 CYP3A4 v\u00e0 P-gp: Nh\u01b0 rifampicin, carbamazepine, phenytoin. C\u00e1c thu\u1ed1c n\u00e0y l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a Rivaroxaban.<\/li>\n<li>Th\u1eadn tr\u1ecdng khi d\u00f9ng chung v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u, NSAIDs do l\u00e0m t\u0103ng nguy c\u01a1 xu\u1ea5t huy\u1ebft.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Xelostad 20 ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 \u0111ang cho con b\u00fa do thi\u1ebfu d\u1eef li\u1ec7u an to\u00e0n v\u00e0 nguy c\u01a1 g\u00e2y h\u1ea1i cho thai nhi\/tr\u1ebb s\u01a1 sinh.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ch\u00f3ng m\u1eb7t ho\u1eb7c ng\u1ea5t (\u00edt g\u1eb7p). B\u1ec7nh nh\u00e2n g\u1eb7p ph\u1ea3i c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0y kh\u00f4ng n\u00ean l\u00e1i xe hay v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Qu\u00e1 li\u1ec1u Rivaroxaban l\u00e0m t\u0103ng cao nguy c\u01a1 ch\u1ea3y m\u00e1u. Hi\u1ec7n nay \u0111\u00e3 c\u00f3 ch\u1ea5t gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u l\u00e0 Andexanet alfa, tuy nhi\u00ean kh\u00f4ng ph\u1ed5 bi\u1ebfn. Trong tr\u01b0\u1eddng h\u1ee3p nghi ng\u1edd qu\u00e1 li\u1ec1u, c\u1ea7n \u0111\u01b0a b\u1ec7nh nh\u00e2n \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf g\u1ea7n nh\u1ea5t ngay l\u1eadp t\u1ee9c. C\u00e1c bi\u1ec7n ph\u00e1p x\u1eed tr\u00ed c\u00f3 th\u1ec3 bao g\u1ed3m s\u1eed d\u1ee5ng than ho\u1ea1t t\u00ednh \u0111\u1ec3 gi\u1ea3m h\u1ea5p thu v\u00e0 c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 c\u1ea7m m\u00e1u.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n thu\u1ed1c Xelostad 20 \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng, d\u01b0\u1edbi 30\u00b0C, \u1edf n\u01a1i kh\u00f4 r\u00e1o, tr\u00e1nh \u00e1nh s\u00e1ng tr\u1ef1c ti\u1ebfp v\u00e0 \u0111\u1ec3 xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Xelostad 20<\/h2>\n<p><a href=\"https:\/\/vnras.com\/drug\/xaravix-10\/\">Xaravix 10<\/a> l\u00e0 s\u1ea3n ph\u1ea9m c\u1ee7a c\u00f4ng ty D\u01b0\u1ee3c H\u1eadu Giang (Vi\u1ec7t Nam), ch\u1ee9a ho\u1ea1t ch\u1ea5t Rivaroxaban 10mg, c\u00f3 c\u00f4ng d\u1ee5ng ch\u00ednh trong vi\u1ec7c d\u1ef1 ph\u00f2ng huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u \u1edf b\u1ec7nh nh\u00e2n sau ph\u1eabu thu\u1eadt thay kh\u1edbp h\u00e1ng ho\u1eb7c kh\u1edbp g\u1ed1i.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Juan Jia, Shi-Min Xue. Efficacy of rivaroxaban for pulmonary embolism, truy c\u1eadp ng\u00e0y 05 th\u00e1ng 08 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31008951\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/31008951\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>S\u1ea3n ph\u1ea9m thu\u1ed1c Xelostad 20 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean Doanh Stellapharm &#8211; chi nh\u00e1nh 1, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-35501-21, d\u1ef1 ph\u00f2ng \u0111\u1ed9t qu\u1ef5 v\u00e0 thuy\u00ean t\u1eafc m\u1ea1ch to\u00e0n th\u00e2n.<\/p>\n","protected":false},"author":1,"featured_media":130765,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-130762","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/130762","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=130762"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/130765"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=130762"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=130762"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=130762"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}