{"id":127571,"date":"2025-07-17T13:35:34","date_gmt":"2025-07-17T06:35:34","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=127571"},"modified":"2025-07-24T11:46:10","modified_gmt":"2025-07-24T04:46:10","slug":"cosopt-5ml","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/cosopt-5ml\/","title":{"rendered":"Cosopt 5ml"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Cosopt 5ml c\u00f3 c\u01a1 s\u1edf s\u1ea3n xu\u1ea5t l\u00e0 Santen Pharmaceutical Co., Ltd. &#8211; Nh\u00e0 m\u00e1y Noto, \u0111\u01b0\u1ee3c l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam v\u1edbi s\u1ed1 \u0111\u0103ng k\u00fd l\u00e0 499110358024.<\/strong><\/p>\n<h2 style=\"text-align: justify;\">Cosopt 5ml l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3 style=\"text-align: justify;\">Th\u00e0nh ph\u1ea7n<\/h3>\n<p style=\"text-align: justify;\">M\u1ed7i l\u1ecd<strong>\u00a0Cosopt 5ml <\/strong>ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul style=\"text-align: justify;\">\n<li>Dorzolamid (d\u01b0\u1edbi d\u1ea1ng dorzolamid hydroclorid) 100mg\/5ml<\/li>\n<li>Timolol (d\u01b0\u1edbi d\u1ea1ng timolol maleat) 25mg\/5ml<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/li>\n<\/ul>\n<p style=\"text-align: justify;\">D\u1ea1ng b\u00e0o ch\u1ebf : Dung d\u1ecbch nh\u1ecf m\u1eaft<\/p>\n<h3 style=\"text-align: justify;\">Tr\u00ecnh b\u00e0y<\/h3>\n<p style=\"text-align: justify;\">S\u0110K: 499110358024<\/p>\n<p style=\"text-align: justify;\">Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd x 5ml<\/p>\n<p style=\"text-align: justify;\">Xu\u1ea5t x\u1ee9: Nh\u1eadt B\u1ea3n<\/p>\n<h2 style=\"text-align: justify;\">T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Cosopt 5ml<\/h2>\n<h3 style=\"text-align: justify;\">C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p style=\"text-align: justify;\">Dorzolamid hydroclorid ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc enzyme carbonic anhydrase II t\u1ea1i c\u00e1c t\u1ebf b\u00e0o th\u1ec3 mi, t\u1eeb \u0111\u00f3 l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh t\u1ea1o th\u00e0nh ion bicarbonat. K\u1ebft qu\u1ea3 l\u00e0 s\u1ef1 v\u1eadn chuy\u1ec3n natri v\u00e0 d\u1ecbch v\u00e0o l\u00f2ng nh\u00e3n th\u1ea5t gi\u1ea3m, d\u1eabn \u0111\u1ebfn gi\u1ea3m t\u1ed5ng h\u1ee3p th\u1ee7y d\u1ecbch.<\/p>\n<p style=\"text-align: justify;\">Timolol maleat l\u00e0 ch\u1ea5t \u0111\u1ed1i kh\u00e1ng kh\u00f4ng ch\u1ecdn l\u1ecdc c\u1ee7a th\u1ee5 th\u1ec3 \u03b2\u2011adrenergic, m\u1eb7c d\u00f9 c\u01a1 ch\u1ebf ch\u00ednh x\u00e1c trong vi\u1ec7c h\u1ea1 nh\u00e3n \u00e1p ch\u01b0a \u0111\u01b0\u1ee3c l\u00e0m r\u00f5 ho\u00e0n to\u00e0n, nhi\u1ec1u nghi\u00ean c\u1ee9u cho th\u1ea5y timolol ch\u1ee7 y\u1ebfu gi\u1ea3m s\u1ea3n xu\u1ea5t th\u1ee7y d\u1ecbch, v\u00e0 trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p c\u00f2n c\u00f3 th\u1ec3 t\u0103ng nh\u1eb9 qu\u00e1 tr\u00ecnh tho\u00e1t th\u1ee7y d\u1ecbch.<\/p>\n<p style=\"text-align: justify;\">Khi ph\u1ed1i h\u1ee3p hai th\u00e0nh ph\u1ea7n n\u00e0y, thu\u1ed1c \u0111em l\u1ea1i hi\u1ec7u qu\u1ea3 gi\u1ea3m \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n t\u0103ng v\u01b0\u1ee3t tr\u1ed9i so v\u1edbi t\u1eebng ho\u1ea1t ch\u1ea5t \u0111\u01a1n \u0111\u1ed9c. Sau khi nh\u1ecf v\u00e0o m\u1eaft, dung d\u1ecbch n\u00e0y gi\u00fap gi\u1ea3m \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n\u2014y\u1ebfu t\u1ed1 nguy c\u01a1 l\u1edbn trong qu\u00e1 tr\u00ecnh t\u1ed5n th\u01b0\u01a1ng th\u1ea7n kinh th\u1ecb gi\u00e1c v\u00e0 m\u1ea5t th\u1ecb l\u1ef1c do gl\u00f4com\u2014m\u00e0 kh\u00f4ng g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n th\u01b0\u1eddng g\u1eb7p nh\u01b0 co \u0111\u1ed3ng t\u1eed, r\u1ed1i lo\u1ea1n \u0111i\u1ec1u ti\u1ebft hay qu\u00e1ng g\u00e0.<\/p>\n<h3 style=\"text-align: justify;\">\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<h4 style=\"text-align: justify;\">H\u1ea5p thu<\/h4>\n<p>Khi nh\u1ecf m\u1eaft, dorzolamid ph\u00e1t huy t\u00e1c d\u1ee5ng t\u1ea1i ch\u1ed7 \u1edf n\u1ed3ng \u0111\u1ed9 th\u1ea5p n\u00ean \u00edt b\u1ecb h\u1ea5p thu to\u00e0n th\u00e2n. \u1ede li\u1ec1u \u0111i\u1ec1u tr\u1ecb, thu\u1ed1c v\u1eabn \u0111\u1ee7 kh\u1ea3 n\u0103ng gi\u1ea3m nh\u00e3n \u00e1p m\u00e0 kh\u00f4ng g\u00e2y r\u1ed1i lo\u1ea1n c\u00e2n b\u1eb1ng axit\u2013baz\u01a1 hay thay \u0111\u1ed5i \u0111i\u1ec7n gi\u1ea3i nh\u01b0 c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf carbonic anhydrase d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng.<\/p>\n<p>Timolol \u0111\u01b0\u1ee3c h\u1ea5p thu v\u00e0o tu\u1ea7n ho\u00e0n to\u00e0n th\u00e2n v\u1edbi n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trung b\u00ecnh trong huy\u1ebft t\u01b0\u01a1ng l\u1ea7n l\u01b0\u1ee3t l\u00e0 0,46ng\/ml sau li\u1ec1u bu\u1ed5i s\u00e1ng v\u00e0 0,35ng\/ml sau li\u1ec1u bu\u1ed5i chi\u1ec1u sau khi nh\u1ecf m\u1eaft dung d\u1ecbch timolol maleat 0,5% hai l\u1ea7n m\u1ed7i ng\u00e0y.<\/p>\n<h4 style=\"text-align: justify;\">Ph\u00e2n b\u1ed1<\/h4>\n<p>Dorzolamid sau khi d\u00f9ng t\u1ea1i ch\u1ed7 c\u00f3 th\u1ec3 v\u00e0o tu\u1ea7n ho\u00e0n chung, tuy nhi\u00ean n\u1ed3ng \u0111\u1ed9 t\u1ef1 do trong huy\u1ebft t\u01b0\u01a1ng r\u1ea5t th\u1ea5p. Thu\u1ed1c t\u00edch l\u0169y ch\u1ee7 y\u1ebfu trong h\u1ed3ng c\u1ea7u nh\u1edd \u00e1i l\u1ef1c ch\u1ecdn l\u1ecdc v\u1edbi carbonic anhydrase II (CA\u2011II).<\/p>\n<h4 style=\"text-align: justify;\">Chuy\u1ec3n h\u00f3a<\/h4>\n<p style=\"text-align: justify;\">Dorzolamid b\u1ecb kh\u1eed ethyl t\u1ea1o th\u00e0nh ch\u1ea5t chuy\u1ec3n h\u00f3a N\u2011desethyl, c\u00f3 ho\u1ea1t t\u00ednh \u1ee9c ch\u1ebf CA\u2011II k\u00e9m h\u01a1n v\u00e0 \u0111\u1ed3ng th\u1eddi t\u00e1c d\u1ee5ng l\u00ean isoenzym CA\u2011I. Ch\u1ea5t chuy\u1ec3n h\u00f3a n\u00e0y c\u0169ng t\u00edch l\u0169y trong h\u1ed3ng c\u1ea7u nh\u1edd g\u1eafn v\u1edbi CA\u2011I.<\/p>\n<h4 style=\"text-align: justify;\">Th\u1ea3i tr\u1eeb<\/h4>\n<p style=\"text-align: justify;\">Thu\u1ed1c g\u1ed1c v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu th\u1ea3i qua \u0111\u01b0\u1eddng n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i.<\/p>\n<p style=\"text-align: justify;\">Sau khi ng\u01b0ng d\u00f9ng, dorzolamid r\u00fat kh\u1ecfi h\u1ed3ng c\u1ea7u theo c\u01a1 ch\u1ebf kh\u00f4ng tuy\u1ebfn t\u00ednh: giai \u0111o\u1ea1n \u0111\u1ea7u n\u1ed3ng \u0111\u1ed9 gi\u1ea3m nhanh, sau \u0111\u00f3 c\u00f3 pha th\u1ea3i tr\u1eeb ch\u1eadm v\u1edbi th\u1eddi gian b\u00e1n th\u1ea3i x\u1ea5p x\u1ec9 4 th\u00e1ng.<\/p>\n<h2 style=\"text-align: justify;\">Cosopt 5ml \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p style=\"text-align: justify;\"><strong>Cosopt 5ml Dorzolamid<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n t\u0103ng \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc gl\u00f4c\u00f4m g\u00f3c m\u1edf ho\u1eb7c gl\u00f4c\u00f4m do gi\u1ea3 bong bao, khi li\u1ec7u ph\u00e1p \u0111\u01a1n tr\u1ecb b\u1eb1ng thu\u1ed1c ch\u1eb9n \u03b2\u2011adrenergic t\u1ea1i ch\u1ed7 kh\u00f4ng \u0111\u1ea1t hi\u1ec7u qu\u1ea3.<\/p>\n<figure id=\"attachment_127573\" aria-describedby=\"caption-attachment-127573\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-127573\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/cosopt-5ml-dieu-tri-ap-luc-noi-nhan-tang.jpg\" alt=\"Cosopt 5ml \u0111i\u1ec1u tr\u1ecb \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n t\u0103ng\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/cosopt-5ml-dieu-tri-ap-luc-noi-nhan-tang.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/cosopt-5ml-dieu-tri-ap-luc-noi-nhan-tang-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/cosopt-5ml-dieu-tri-ap-luc-noi-nhan-tang-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/cosopt-5ml-dieu-tri-ap-luc-noi-nhan-tang-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-127573\" class=\"wp-caption-text\">Cosopt 5ml \u0111i\u1ec1u tr\u1ecb \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n t\u0103ng<\/figcaption><\/figure>\n<h2 style=\"text-align: justify;\">Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Cosopt 5ml<\/h2>\n<p>Li\u1ec1u d\u00f9ng: Nh\u1ecf 1 gi\u1ecdt Cosopt 5ml v\u00e0o t\u00fai k\u1ebft m\u1ea1c c\u1ee7a m\u1eaft c\u1ea7n \u0111i\u1ec1u tr\u1ecb, 2 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>N\u1ebfu \u0111ang d\u00f9ng th\u00eam b\u1ea5t k\u1ef3 thu\u1ed1c nh\u1ecf m\u1eaft kh\u00e1c, h\u00e3y ch\u1edd \u00edt nh\u1ea5t 10\u202fph\u00fat sau khi nh\u1ecf COSOPT tr\u01b0\u1edbc khi d\u00f9ng thu\u1ed1c ti\u1ebfp theo.<\/p>\n<p>L\u01b0u \u00fd :<\/p>\n<ul style=\"text-align: justify;\">\n<li>R\u1eeda tay s\u1ea1ch s\u1ebd tr\u01b0\u1edbc khi thao t\u00e1c.<\/li>\n<li>Tr\u00e1nh \u0111\u1ec3 \u0111\u1ea7u l\u1ecd ti\u1ebfp x\u00fac tr\u1ef1c ti\u1ebfp v\u1edbi m\u00ed m\u1eaft, l\u00f4ng mi ho\u1eb7c b\u1ea5t k\u1ef3 b\u1ec1 m\u1eb7t n\u00e0o \u0111\u1ec3 h\u1ea1n ch\u1ebf nguy c\u01a1 nhi\u1ec5m khu\u1ea9n.<\/li>\n<li>Kh\u00f3a ch\u1eb7t sau m\u1ed7i l\u1ea7n s\u1eed d\u1ee5ng, tr\u00e1nh va ch\u1ea1m, ki\u1ec3m tra h\u1ea1n d\u00f9ng v\u00e0 kh\u00f4ng \u0111\u1ec3 l\u1ecd thu\u1ed1c ti\u1ebfp x\u00fac v\u1edbi ngu\u1ed3n \u00f4 nhi\u1ec5m. Dung d\u1ecbch nh\u1ecf m\u1eaft n\u1ebfu b\u1ecb nhi\u1ec5m vi khu\u1ea9n c\u00f3 th\u1ec3 g\u00e2y vi\u00eam nhi\u1ec5m nghi\u00eam tr\u1ecdng, d\u1eabn \u0111\u1ebfn t\u1ed5n th\u01b0\u01a1ng gi\u00e1c m\u1ea1c v\u00e0 m\u1ea5t th\u1ecb l\u1ef1c.<\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\">C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Cosopt 5ml<\/h2>\n<p>B\u01b0\u1edbc 1 : R\u1eeda tay th\u1eadt s\u1ea1ch v\u1edbi x\u00e0 ph\u00f2ng v\u00e0 lau kh\u00f4.<\/p>\n<p>B\u01b0\u1edbc 2 : M\u1edf l\u1ecd: tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng \u0111\u1ec3 \u0111\u1ea7u l\u1ecd ch\u1ea1m v\u00e0o m\u1eaft, v\u00f9ng da quanh m\u1eaft ho\u1eb7c ng\u00f3n tay.<\/p>\n<p>B\u01b0\u1edbc 3 : Ng\u1eeda nh\u1eb9 \u0111\u1ea7u ra sau, gi\u1eef l\u1ecd l\u1ed9n ng\u01b0\u1ee3c ngay ph\u00eda tr\u00ean m\u1eaft c\u1ea7n nh\u1ecf.<\/p>\n<p>B\u01b0\u1edbc 4 : K\u00e9o nh\u1eb9 m\u00ed d\u01b0\u1edbi xu\u1ed1ng, m\u1eaft h\u01b0\u1edbng l\u00ean tr\u1ea7n, r\u1ed3i b\u00f3p nh\u1eb9 ph\u1ea7n d\u1eb9t c\u1ee7a l\u1ecd \u0111\u1ec3 nh\u1ecf 1 gi\u1ecdt v\u00e0o khe h\u1edf gi\u1eefa m\u00ed v\u00e0 nh\u00e3n c\u1ea7u.<\/p>\n<p>B\u01b0\u1edbc 5 : Sau khi nh\u1ecf xong, \u1ea5n m\u1ed9t ng\u00f3n tay v\u00e0o kh\u00f3e m\u1eaft g\u1ea7n m\u0169i ho\u1eb7c nh\u1eb9 nh\u00e0ng nh\u1eafm m\u1eaft trong 2 ph\u00fat \u0111\u1ec3 thu\u1ed1c l\u01b0u l\u1ea1i v\u00e0 h\u1ea1n ch\u1ebf h\u1ea5p thu to\u00e0n th\u00e2n.<\/p>\n<p>B\u01b0\u1edbc 6 : L\u1eb7p l\u1ea1i c\u00e1c b\u01b0\u1edbc t\u1eeb 3\u20135 cho m\u1eaft c\u00f2n l\u1ea1i n\u1ebfu b\u00e1c s\u0129 ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb hai b\u00ean.<\/p>\n<p>B\u01b0\u1edbc 7 : \u0110\u00f3ng l\u1ecd: \u0111\u1eb7t n\u1eafp tr\u1edf l\u1ea1i, \u0111\u00f3ng ch\u1eb7t \u0111\u1ec3 b\u1ea3o \u0111\u1ea3m v\u00f4 tr\u00f9ng v\u00e0 b\u1ea3o qu\u1ea3n thu\u1ed1c.<\/p>\n<h2 style=\"text-align: justify;\">Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Cosopt 5ml trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Kh\u00f4ng d\u00f9ng Cosopt 5ml cho ng\u01b0\u1eddi c\u00f3 m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>R\u1ed1i lo\u1ea1n h\u00f4 h\u1ea5p: hen ph\u1ebf qu\u1ea3n (hi\u1ec7n t\u1ea1i ho\u1eb7c ti\u1ec1n s\u1eed) ho\u1eb7c b\u1ec7nh ph\u1ed5i t\u1eafc ngh\u1ebdn m\u1ea1n t\u00ednh n\u1eb7ng.<\/p>\n<p>R\u1ed1i lo\u1ea1n nh\u1ecbp tim n\u1eb7ng: nh\u1ecbp xoang ch\u1eadm, h\u1ed9i ch\u1ee9ng suy n\u00fat xoang, block nh\u0129\u2011xoang, block nh\u0129\u2011th\u1ea5t \u0111\u1ed9 II ho\u1eb7c III kh\u00f4ng ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c v\u1edbi m\u00e1y t\u1ea1o nh\u1ecbp, suy tim n\u1eb7ng, s\u1ed1c tim.<\/p>\n<p>Suy th\u1eadn n\u1eb7ng: \u0111\u1ed9 l\u1ecdc c\u1ea7u th\u1eadn &lt;\u202f30\u202fml\/ph\u00fat ho\u1eb7c c\u00f3 t\u00ecnh tr\u1ea1ng nhi\u1ec5m toan t\u0103ng clo huy\u1ebft.<\/p>\n<h2 style=\"text-align: justify;\">L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Cosopt 5ml<\/h2>\n<h3 style=\"text-align: justify;\">Th\u1eadn tr\u1ecdng<\/h3>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng cho ng\u01b0\u1eddi c\u00f3 b\u1ec7nh m\u1ea1ch v\u00e0nh, \u0111au th\u1eaft ng\u1ef1c Prinzmetal, suy tim, block tim \u0111\u1ed9 I, ho\u1eb7c h\u1ea1 huy\u1ebft \u00e1p.<\/p>\n<p>C\u00f3 th\u1ec3 g\u00e2y co th\u1eaft ph\u1ebf qu\u1ea3n, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n hen ho\u1eb7c COPD (m\u1ee9c \u0111\u1ed9 nh\u1eb9\u2013v\u1eeba). Ch\u1ec9 d\u00f9ng n\u1ebfu l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i r\u1ee7i ro, theo d\u00f5i ch\u1eb7t ch\u1ebd t\u00ecnh tr\u1ea1ng h\u00f4 h\u1ea5p.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng cho ng\u01b0\u1eddi c\u00f3 Raynaud n\u1eb7ng ho\u1eb7c r\u1ed1i lo\u1ea1n tu\u1ea7n ho\u00e0n ngo\u1ea1i bi\u00ean.<\/p>\n<p>Ng\u1eebng thu\u1ed1c ngay n\u1ebfu xu\u1ea5t hi\u1ec7n ph\u00e1t ban, ph\u00f9 m\u1ea1ch, suy \u0111a t\u1ea1ng ho\u1eb7c c\u00e1c d\u1ea5u hi\u1ec7u d\u1ecb \u1ee9ng n\u1eb7ng.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng cho b\u1ec7nh nh\u00e2n suy gan.<\/p>\n<p>Gi\u1ea3m li\u1ec1u t\u1eeb t\u1eeb \u1edf b\u1ec7nh nh\u00e2n m\u1ea1ch v\u00e0nh.<\/p>\n<p>Che l\u1ea5p tri\u1ec7u ch\u1ee9ng c\u1ee7a \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng v\u00e0 h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, c\u1ea7n theo d\u00f5i \u0111\u01b0\u1eddng huy\u1ebft ch\u1eb7t.<\/p>\n<p>C\u00f3 th\u1ec3 che gi\u1ea5u d\u1ea5u hi\u1ec7u c\u01b0\u1eddng gi\u00e1p.<\/p>\n<p>G\u00e2y kh\u00f4, k\u00edch \u1ee9ng m\u1eaft \u1edf ng\u01b0\u1eddi c\u00f3 b\u1ec7nh gi\u00e1c m\u1ea1c.<\/p>\n<p>C\u00f3 th\u1ec3 l\u00e0m n\u1eb7ng th\u00eam tri\u1ec7u ch\u1ee9ng nh\u01b0\u1ee3c c\u01a1.<\/p>\n<p>M\u1eb7c d\u00f9 hi\u1ebfm, b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed s\u1ecfi th\u1eadn v\u1eabn c\u00f3 th\u1ec3 g\u1eb7p s\u1ecfi ni\u1ec7u do h\u1ea5p thu dorzolamid.<\/p>\n<p>Thu\u1ed1c ch\u01b0a \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u cho c\u01a1n gl\u00f4c\u00f4m g\u00f3c \u0111\u00f3ng c\u1ea5p t\u00ednh, c\u1ea7n can thi\u1ec7p chuy\u00ean khoa.<\/p>\n<p>C\u00f3 th\u1ec3 g\u00e2y ph\u00f9 gi\u00e1c m\u1ea1c, m\u1ea5t b\u00f9 gi\u00e1c m\u1ea1c kh\u00f4ng h\u1ed3i ph\u1ee5c, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n c\u00f3 n\u1ed9i m\u00f4 gi\u1ea3m ho\u1eb7c ti\u1ec1n s\u1eed ph\u1eabu thu\u1eadt n\u1ed9i nh\u00e3n.<\/p>\n<p>Ch\u1ee9a benzalkonium clorid, c\u00f3 th\u1ec3 k\u00edch \u1ee9ng v\u00e0 \u0111\u1ed5i m\u00e0u k\u00ednh \u00e1p tr\u00f2ng m\u1ec1m. Th\u00e1o k\u00ednh \u00e1p tr\u00f2ng tr\u01b0\u1edbc khi nh\u1ecf, \u0111\u1ee3i t\u1ed1i thi\u1ec3u 15\u202fph\u00fat r\u1ed3i \u0111eo l\u1ea1i.<\/p>\n<h3 style=\"text-align: justify;\">T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Hay g\u1eb7p : n\u00f3ng v\u00e0 cay m\u1eaft, r\u1ed1i lo\u1ea1n v\u1ecb gi\u00e1c,<\/p>\n<p>Th\u01b0\u1eddng g\u1eb7p : ng\u1ee9a m\u1eaft, ch\u1ea3y n\u01b0\u1edbc m\u1eaft, kh\u00f4 m\u1eaft, tr\u1ee3t x\u01b0\u1edbc gi\u00e1c m\u1ea1c, k\u00edch \u1ee9ng m\u00ed m\u1eaft, sung huy\u1ebft k\u1ebft m\u1ea1c, vi\u00eam m\u00ed m\u1eaft, nh\u00ecn m\u1edd, vi\u00eam xoang, bu\u1ed3n n\u00f4n, m\u1ec7t m\u1ecfi, suy nh\u01b0\u1ee3c<\/p>\n<p>\u00cdt g\u1eb7p : nh\u1ecbp tim ch\u1eadm, tr\u1ea7m c\u1ea3m, ch\u00f3ng m\u1eb7t, ng\u1ea5t, r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c, kh\u00f3 ti\u00eau, kh\u00f3 th\u1edf, vi\u00eam th\u1ec3 m\u1ed1ng\u2011m\u1eaft \u2013 th\u1ec3 mi, s\u1ecfi ni\u1ec7u<\/p>\n<p>Hi\u1ebfm g\u1eb7p : ho\u1ea1i t\u1eed th\u01b0\u1ee3ng b\u00ec nhi\u1ec5m \u0111\u1ed9c, h\u1ed9i ch\u1ee9ng Stevens\u2013Johnson, ph\u00e1t ban, m\u00e0y \u0111ay, ph\u1ea3n v\u1ec7, d\u1ecb \u1ee9ng, ph\u00f9 m\u1ea1ch, v\u1ea3y n\u1ebfn, lupus ban \u0111\u1ecf h\u1ec7 th\u1ed1ng, b\u1ec7nh Peyronie, r\u1ee5ng t\u00f3c, d\u1ecb c\u1ea3m, nh\u01b0\u1ee3c c\u01a1, m\u1ea5t ng\u1ee7, \u00e1c m\u1ed9ng, m\u1ea5t tr\u00ed nh\u1edb, tai bi\u1ebfn m\u1ea1ch m\u00e1u n\u00e3o, thi\u1ebfu m\u00e1u n\u00e3o c\u1ee5c b\u1ed9, gi\u1ea3m ham mu\u1ed1n, \u0111\u1ecf m\u1eaft, \u0111au m\u1eaft, m\u00ed m\u1eaft \u0111\u00f3ng g\u1ec9, c\u1eadn th\u1ecb tho\u00e1ng qua, ph\u00f9 gi\u00e1c m\u1ea1c, \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n th\u1ea5p, bong h\u1eafc m\u1ea1c, s\u1ee5p mi, song th\u1ecb, \u00f9 tai, \u0111au ng\u1ef1c, \u0111\u00e1nh tr\u1ed1ng ng\u1ef1c, lo\u1ea1n nh\u1ecbp tim, suy tim sung huy\u1ebft, ng\u1eebng tim, block tim, h\u1ea1 huy\u1ebft \u00e1p, \u0111au ch\u00e2n khi \u0111i b\u1ed9, Raynaud, tay ch\u00e2n l\u1ea1nh, suy h\u00f4 h\u1ea5p, co th\u1eaft ph\u1ebf qu\u1ea3n, ch\u1ea3y m\u00e1u cam, ho, k\u00edch \u1ee9ng h\u1ecdng, kh\u00f4 mi\u1ec7ng, ti\u00eau ch\u1ea3y, vi\u00eam da ti\u1ebfp x\u00fac<\/p>\n<p>Ch\u01b0a r\u00f5 t\u1ea7n su\u1ea5t: \u1ea3o gi\u00e1c, h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, \u0111au c\u01a1, ng\u1ee9a, block nh\u0129\u2011th\u1ea5t, r\u1ed1i lo\u1ea1n t\u00ecnh d\u1ee5c, c\u1ea3m gi\u00e1c c\u00f3 v\u1eadt l\u1ea1 trong m\u1eaft, ch\u1ea3y n\u01b0\u1edbc m\u1eaft, ng\u1ee9a m\u1eaft, suy tim, kh\u00f3 th\u1edf<\/p>\n<h3 style=\"text-align: justify;\">T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng Cosopt 5ml c\u00f9ng thu\u1ed1c ch\u1eb9n k\u00eanh calci \u0111\u01b0\u1eddng u\u1ed1ng, thu\u1ed1c gi\u1ea3m catecholamin, thu\u1ed1c ch\u1eb9n \u03b2\u2011adrenergic kh\u00e1c, thu\u1ed1c ch\u1ed1ng lo\u1ea1n nh\u1ecbp (amiodaron), digitalis glycosid, thu\u1ed1c \u0111\u1ed1i giao c\u1ea3m, guanethidin ho\u1eb7c thu\u1ed1c \u1ee9c ch\u1ebf MAO do c\u00f3 th\u1ec3 g\u00e2y h\u1ea1 huy\u1ebft \u00e1p qu\u00e1 m\u1ee9c v\u00e0 ho\u1eb7c l\u00e0m ch\u1eadm nh\u1ecbp tim nghi\u00eam tr\u1ecdng.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf CYP2D6 (quinidin, fluoxetin, paroxetin) do c\u00f3 th\u1ec3 l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng ch\u1eb9n \u03b2 to\u00e0n th\u00e2n (gi\u1ea3m nh\u1ecbp tim, tr\u1ea7m c\u1ea3m).<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng \u0111\u1ed3ng th\u1eddi timolol maleat v\u1edbi dung d\u1ecbch nh\u1ecf m\u1eaft omidenepag isopropyl v\u00ec c\u00f3 th\u1ec3 l\u00e0m t\u0103ng t\u1ea7n su\u1ea5t ph\u1ea3n \u1ee9ng vi\u00eam m\u1eaft (sung huy\u1ebft k\u1ebft m\u1ea1c).<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng thu\u1ed1c nh\u1ecf m\u1eaft ch\u1ee9a adrenaline (epinephrin) do c\u00f3 th\u1ec3 g\u00e2y gi\u00e3n \u0111\u1ed3ng t\u1eed kh\u00f4ng mong mu\u1ed1n.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng v\u00ec thu\u1ed1c ch\u1eb9n \u03b2 c\u00f3 th\u1ec3 l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng clonidin \u0111\u01b0\u1eddng u\u1ed1ng ho\u1eb7c sau khi ng\u01b0ng clonidin v\u00ec c\u00f3 th\u1ec3 l\u00e0m tr\u1ea7m tr\u1ecdng t\u00ecnh tr\u1ea1ng t\u0103ng huy\u1ebft \u00e1p d\u1ed9i ng\u01b0\u1ee3c.<\/p>\n<p>C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf ACE, thu\u1ed1c l\u1ee3i ti\u1ec3u, NSAID (k\u1ec3 c\u1ea3 aspirin) v\u00e0 hormone (estrogen, insulin, thyroxin) \u0111\u00e3 \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ed3ng th\u1eddi m\u00e0 kh\u00f4ng ghi nh\u1eadn t\u01b0\u01a1ng t\u00e1c b\u1ea5t l\u1ee3i \u0111\u00e1ng k\u1ec3.<\/p>\n<h3 style=\"text-align: justify;\">L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p style=\"text-align: justify;\">Kh\u00f4ng d\u00f9ng thu\u1ed1c cho ph\u1ee5 n\u1eef c\u00f3 thai<\/p>\n<p style=\"text-align: justify;\">N\u1ebfu b\u1eaft bu\u1ed9c ph\u1ea3i \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Cosopt 5ml, kh\u00f4ng cho con b\u00fa.<\/p>\n<h3 style=\"text-align: justify;\">Kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p style=\"text-align: justify;\">Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u v\u1ec1 \u1ea3nh h\u01b0\u1edfng c\u1ee7a thu\u1ed1c l\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c. Tuy nhi\u00ean Cosopt 5ml c\u00f3 th\u1ec3 g\u00e2y t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n nh\u01b0 nh\u00ecn m\u1edd hay r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c, c\u1ea7n th\u1eadn tr\u1ecdng.<\/p>\n<h3 style=\"text-align: justify;\">Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tri\u1ec7u ch\u1ee9ng : ch\u00f3ng m\u1eb7t, nh\u1ee9c \u0111\u1ea7u, th\u1edf ng\u1eafn, ch\u1eadm nh\u1ecbp tim, co th\u1eaft ph\u1ebf qu\u1ea3n, ng\u1eebng tim.<\/p>\n<p style=\"text-align: justify;\">X\u1eed tr\u00ed : B\u00e1o ngay v\u1edbi b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb v\u00e0 \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf g\u1ea7n nh\u1ea5t \u0111\u1ec3 ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng k\u1ecbp th\u1eddi.<\/p>\n<h3 style=\"text-align: justify;\">B\u1ea3o qu\u1ea3n<\/h3>\n<p style=\"text-align: justify;\">\u0110\u1ec3 thu\u1ed1c tr\u00e1nh xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<p style=\"text-align: justify;\">B\u1ea3o qu\u1ea3n thu\u1ed1c \u1edf nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30 \u0111\u1ed9 C, tr\u00e1nh \u00e1nh n\u1eafng tr\u1ef1c ti\u1ebfp t\u1eeb m\u1eb7t tr\u1eddi.<\/p>\n<h2 style=\"text-align: justify;\">S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p style=\"text-align: justify;\">Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<\/p>\n<ul>\n<li style=\"text-align: justify;\"><a href=\"https:\/\/vnras.com\/drug\/timo-drop\/\">Thu\u1ed1c Timo Drop<\/a> \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb t\u0103ng nh\u00e3n \u00e1p, glaucom g\u00f3c m\u1edf m\u00e3n t\u00ednh v\u00e0 m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p glaucom th\u1ee9 ph\u00e1t, gi\u00fap l\u00e0m gi\u1ea3m \u00e1p l\u1ef1c trong m\u1eaft.<\/li>\n<li><a href=\"https:\/\/vnras.com\/drug\/hon-dich-nho-mat-azarga\/\">H\u1ed7n d\u1ecbch nh\u1ecf m\u1eaft Azarga<\/a> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n Timolol maleat, Brinzolamid \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb gi\u1ea3m \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n, b\u1ecb glocom g\u00f3c m\u1edf ho\u1eb7c t\u0103ng nh\u00e3n \u00e1p, m\u00e0 li\u1ec1u \u0111i\u1ec1u tr\u1ecb kh\u00f4ng hi\u1ec7u qu\u1ea3<\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\">T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p style=\"text-align: justify;\">1. H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng \u0111\u01b0\u1ee3c C\u1ee5c qu\u1ea3n l\u00fd ph\u00ea duy\u1ec7t. Xem ngay <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/cosopt-5ml-huong-dan-su-dung.pdf\">T\u1ea0I \u0110\u00c2Y<\/a>.<\/p>\n<p style=\"text-align: justify;\">2. D Ormrod, K McClellan (2000), Topical dorzolamide 2%\/timolol 0.5%: a review of its use in the treatment of open-angle glaucoma. Truy c\u1eadp ng\u00e0y 17\/07\/2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11200308\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/11200308\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cosopt 5ml \u0111i\u1ec1u tr\u1ecb \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n t\u0103ng \u1edf b\u1ec7nh nh\u00e2n m\u1eafc gl\u00f4c\u00f4m g\u00f3c m\u1edf ho\u1eb7c gl\u00f4c\u00f4m do gi\u1ea3 bong bao, khi \u0111\u01a1n tr\u1ecb b\u1eb1ng thu\u1ed1c ch\u1eb9n \u03b2 t\u1ea1i ch\u1ed7 kh\u00f4ng \u0111\u1ea1t hi\u1ec7u qu\u1ea3.<\/p>\n","protected":false},"author":1,"featured_media":127574,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-127571","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/127571","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=127571"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/127574"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=127571"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=127571"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=127571"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}