{"id":127570,"date":"2025-07-17T14:22:40","date_gmt":"2025-07-17T07:22:40","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=127570"},"modified":"2026-03-21T08:42:43","modified_gmt":"2026-03-21T01:42:43","slug":"cosopt-s-0-2ml","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/cosopt-s-0-2ml\/","title":{"rendered":"Cosopt-S 0.2ml"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Cosopt-S 0.2ml \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Santen Pharmaceutical Co., Ltd. &#8211; Nh\u00e0 m\u00e1y Noto, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 499110442023.<\/strong><\/p>\n<h2>Cosopt-S 0.2ml l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i l\u1ecd \u0111\u01a1n li\u1ec1u <strong>Cosopt-S 0.2ml<\/strong> dung d\u1ecbch ch\u1ee9a:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t: 4,452 mg <strong>dorzolamid<\/strong> hydroclorid (t\u01b0\u01a1ng \u0111\u01b0\u01a1ng 4 mg dorzolamid) v\u00e0 1,366 mg timolol maleat (t\u01b0\u01a1ng \u0111\u01b0\u01a1ng 1 mg timolol).<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: Hydroxyethylcellulose, mannitol, natri citrat, natri hydroxyd v\u00e0 n\u01b0\u1edbc pha ti\u00eam.<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 499110442023<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Dung d\u1ecbch nh\u1ecf m\u1eaft<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 T\u00fai x 20 L\u1ecd x 0,2ml<\/p>\n<p>Xu\u1ea5t x\u1ee9: Japan<\/p>\n<figure id=\"attachment_127580\" aria-describedby=\"caption-attachment-127580\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-127580\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Cosopt-S-1.jpg\" alt=\"Cosopt-S h\u1ea1 \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Cosopt-S-1.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Cosopt-S-1-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Cosopt-S-1-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Cosopt-S-1-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-127580\" class=\"wp-caption-text\">Cosopt-S h\u1ea1 \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Cosopt-S 0.2ml<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Cosopt-S k\u1ebft h\u1ee3p hai ho\u1ea1t ch\u1ea5t l\u00e0 dorzolamid hydroclorid v\u00e0 timolol maleat, gi\u00fap h\u1ea1 \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n hi\u1ec7u qu\u1ea3 th\u00f4ng qua hai c\u01a1 ch\u1ebf kh\u00e1c nhau nh\u01b0ng b\u1ed5 tr\u1ee3 cho nhau:<\/p>\n<ul>\n<li>Dorzolamid: L\u00e0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf men carbonic anhydrase II, c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m s\u1ef1 ti\u1ebft th\u1ee7y d\u1ecbch \u1edf m\u1eaft b\u1eb1ng c\u00e1ch l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh h\u00ecnh th\u00e0nh ion bicarbonat.<\/li>\n<li>Timolol: L\u00e0 m\u1ed9t thu\u1ed1c ch\u1eb9n th\u1ee5 th\u1ec3 beta-adrenergic kh\u00f4ng ch\u1ecdn l\u1ecdc, c\u01a1 ch\u1ebf ch\u00ednh l\u00e0 l\u00e0m gi\u1ea3m s\u1ef1 s\u1ea3n xu\u1ea5t th\u1ee7y d\u1ecbch.<\/li>\n<\/ul>\n<p>S\u1ef1 k\u1ebft h\u1ee3p n\u00e0y mang l\u1ea1i hi\u1ec7u qu\u1ea3 h\u1ea1 \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n m\u1ea1nh h\u01a1n so v\u1edbi khi s\u1eed d\u1ee5ng ri\u00eang l\u1ebb t\u1eebng th\u00e0nh ph\u1ea7n.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>Dorzolamid: Khi d\u00f9ng t\u1ea1i ch\u1ed7, dorzolamid t\u00e1c \u0111\u1ed9ng tr\u1ef1c ti\u1ebfp t\u1ea1i m\u1eaft v\u1edbi m\u1ee9c \u0111\u1ed9 ph\u01a1i nhi\u1ec5m to\u00e0n th\u00e2n th\u1ea5p. Ho\u1ea1t ch\u1ea5t t\u00edch l\u0169y trong h\u1ed3ng c\u1ea7u v\u00e0 \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i.<\/li>\n<li>Timolol: Sau khi nh\u1ecf m\u1eaft, timolol \u0111\u01b0\u1ee3c h\u1ea5p thu v\u00e0o tu\u1ea7n ho\u00e0n chung.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Cosopt-S 0.2ml \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Cosopt-S \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb t\u0103ng \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n \u1edf c\u00e1c b\u1ec7nh nh\u00e2n:<\/p>\n<ul>\n<li>T\u0103ng nh\u00e3n \u00e1p.<\/li>\n<li>Gl\u00f4c\u00f4m g\u00f3c m\u1edf.<\/li>\n<li>Gl\u00f4c\u00f4m gi\u1ea3 bong bao ho\u1eb7c gl\u00f4c\u00f4m g\u00f3c m\u1edf th\u1ee9 ph\u00e1t kh\u00e1c.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Cosopt-S 0.2ml<\/h2>\n<p>Li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 nh\u1ecf 1 gi\u1ecdt v\u00e0o t\u00fai k\u1ebft m\u1ea1c c\u1ee7a m\u1eaft b\u1ecb b\u1ec7nh, 2 l\u1ea7n m\u1ed7i ng\u00e0y.<\/p>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Cosopt-S 0.2ml<\/h2>\n<ul>\n<li>R\u1eeda tay s\u1ea1ch tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/li>\n<li>M\u1edf t\u00fai nh\u00f4m v\u00e0 t\u00e1ch 1 l\u1ecd \u0111\u01a1n li\u1ec1u. M\u1ed7i l\u1ecd ch\u1ec9 d\u00f9ng m\u1ed9t l\u1ea7n v\u00e0 n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ngay sau khi m\u1edf.<\/li>\n<li>Xo\u1eafn m\u1edf \u0111\u1ea7u l\u1ecd, ng\u1eeda \u0111\u1ea7u ra sau, k\u00e9o nh\u1eb9 m\u00ed d\u01b0\u1edbi v\u00e0 nh\u1ecf 1 gi\u1ecdt v\u00e0o m\u1eaft. Tr\u00e1nh \u0111\u1ec3 \u0111\u1ea7u l\u1ecd ch\u1ea1m v\u00e0o m\u1eaft ho\u1eb7c v\u00f9ng da xung quanh.<\/li>\n<li>Sau khi nh\u1ecf, nh\u1eafm m\u1eaft v\u00e0 d\u00f9ng ng\u00f3n tay \u1ea5n nh\u1eb9 v\u00e0o kh\u00f3e m\u1eaft trong kho\u1ea3ng 2 ph\u00fat \u0111\u1ec3 gi\u1ea3m s\u1ef1 h\u1ea5p thu thu\u1ed1c v\u00e0o to\u00e0n th\u00e2n.<\/li>\n<li>H\u1ee7y b\u1ecf l\u1ecd thu\u1ed1c ngay sau khi d\u00f9ng, k\u1ec3 c\u1ea3 khi c\u00f2n dung d\u1ecbch b\u00ean trong.<\/li>\n<li>N\u1ebfu \u0111ang d\u00f9ng c\u00f9ng l\u00fac v\u1edbi m\u1ed9t lo\u1ea1i thu\u1ed1c nh\u1ecf m\u1eaft kh\u00e1c, h\u00e3y d\u00f9ng ch\u00fang c\u00e1ch nhau \u00edt nh\u1ea5t 10 ph\u00fat.<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Cosopt-S 0.2ml trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>B\u1ec7nh \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p ph\u1ea3n \u1ee9ng, bao g\u1ed3m hen ph\u1ebf qu\u1ea3n ho\u1eb7c c\u00f3 ti\u1ec1n s\u1eed hen ph\u1ebf qu\u1ea3n, b\u1ec7nh ph\u1ed5i t\u1eafc ngh\u1ebdn m\u1ea1n t\u00ednh (COPD) n\u1eb7ng.<\/li>\n<li>C\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 tim nh\u01b0 nh\u1ecbp xoang ch\u1eadm, h\u1ed9i ch\u1ee9ng suy n\u00fat xoang, block nh\u0129 th\u1ea5t \u0111\u1ed9 2 ho\u1eb7c 3 kh\u00f4ng ki\u1ec3m so\u00e1t, suy tim r\u00f5 r\u1ec7t, s\u1ed1c tim.<\/li>\n<li>B\u1ec7nh nh\u00e2n c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn suy gi\u1ea3m nghi\u00eam tr\u1ecdng (v\u1edbi \u0111\u1ed9 thanh th\u1ea3i creatinin d\u01b0\u1edbi 30 ml\/ph\u00fat) ho\u1eb7c nh\u1eefng ng\u01b0\u1eddi b\u1ecb nhi\u1ec5m toan do n\u1ed3ng \u0111\u1ed9 clo trong m\u00e1u cao.<\/li>\n<li>Qu\u00e1 m\u1eabn v\u1edbi dorzolamid, timolol ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Cosopt-S 0.2ml<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>C\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng cho b\u1ec7nh nh\u00e2n c\u00f3 b\u1ec7nh tim m\u1ea1ch ho\u1eb7c b\u1ec7nh ph\u1ed5i t\u1eafc ngh\u1ebdn m\u1ea1n t\u00ednh (COPD) m\u1ee9c \u0111\u1ed9 nh\u1eb9\/v\u1eeba.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>R\u1ea5t ph\u1ed5 bi\u1ebfn: C\u1ea3m gi\u00e1c n\u00f3ng r\u00e1t v\u00e0 cay m\u1eaft.<\/li>\n<li>Ph\u1ed5 bi\u1ebfn: Sung huy\u1ebft k\u1ebft m\u1ea1c, nh\u00ecn m\u1edd, ng\u1ee9a m\u1eaft, ch\u1ea3y n\u01b0\u1edbc m\u1eaft, vi\u00eam xoang, r\u1ed1i lo\u1ea1n v\u1ecb gi\u00e1c.<\/li>\n<li>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00e1c tr\u00ean m\u1eaft v\u00e0 to\u00e0n th\u00e2n \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o. C\u1ea7n th\u00f4ng b\u00e1o ngay cho b\u00e1c s\u0129 ho\u1eb7c d\u01b0\u1ee3c s\u0129 khi g\u1eb7p ph\u1ea3i c\u00e1c ph\u1ea3n \u1ee9ng c\u00f3 h\u1ea1i.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Vi\u1ec7c s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c ch\u1eb9n k\u00eanh canxi, thu\u1ed1c ch\u1eb9n beta-adrenergic \u0111\u01b0\u1eddng u\u1ed1ng, ho\u1eb7c c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf CYP2D6 (nh\u01b0 quinidin, fluoxetin) c\u00f3 th\u1ec3 l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c.<\/li>\n<li>D\u00f9ng c\u00f9ng thu\u1ed1c ch\u1eb9n beta d\u1eabn \u0111\u1ebfn nguy c\u01a1 h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft cao h\u01a1n.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<ul>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai: Kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng Cosopt-S trong thai k\u1ef3.<\/li>\n<li>Ph\u1ee5 n\u1eef cho con b\u00fa: Kh\u00f4ng khuy\u1ebfn c\u00e1o cho con b\u00fa n\u1ebfu vi\u1ec7c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Cosopt-S l\u00e0 c\u1ea7n thi\u1ebft.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nh\u01b0 nh\u00ecn m\u1edd c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<ul>\n<li>Tri\u1ec7u ch\u1ee9ng: Qu\u00e1 li\u1ec1u timolol c\u00f3 th\u1ec3 g\u00e2y ch\u00f3ng m\u1eb7t, nh\u1ee9c \u0111\u1ea7u, th\u1edf ng\u1eafn, nh\u1ecbp tim ch\u1eadm. Qu\u00e1 li\u1ec1u dorzolamid c\u00f3 th\u1ec3 g\u00e2y m\u1ea5t c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i, t\u00ecnh tr\u1ea1ng nhi\u1ec5m toan.<\/li>\n<li>X\u1eed tr\u00ed: C\u1ea7n \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 h\u1ed7 tr\u1ee3.<\/li>\n<\/ul>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>Burak Turgut, Peykan T\u00fcrk\u00e7\u00fco\u011flu, Mete G\u00fcler, Nuray Akyol, Ulk\u00fc Celiker, Tamer Demir. Anosmia as an adverse effect of dorzolamid, truy c\u1eadp ng\u00e0y 17 th\u00e1ng 07 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17305746\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/17305746\/<\/a><\/li>\n<li>H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Cosopt-S 0.2ml do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p, t\u1ea3i file <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Huong-dan-su-dung-cosopt-S.pdf\">t\u1ea1i \u0111\u00e2y<\/a>.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Cosopt-S 0.2ml \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Santen Pharmaceutical Co., Ltd. &#8211; Nh\u00e0 m\u00e1y Noto, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 499110442023, \u0111i\u1ec1u tr\u1ecb t\u0103ng \u00e1p l\u1ef1c n\u1ed9i nh\u00e3n.<\/p>\n","protected":false},"author":1,"featured_media":127581,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-127570","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/127570","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=127570"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/127581"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=127570"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=127570"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=127570"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}