{"id":127220,"date":"2025-07-15T15:51:09","date_gmt":"2025-07-15T08:51:09","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=127220"},"modified":"2025-07-24T11:46:14","modified_gmt":"2025-07-24T04:46:14","slug":"alexan","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/alexan\/","title":{"rendered":"Alexan"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Alexan c\u00f3 c\u01a1 s\u1edf s\u1ea3n xu\u1ea5t l\u00e0 Ebewe Pharma Ges.m.b.H. Nfg. KG, \u0111\u01b0\u1ee3c l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam v\u1edbi s\u1ed1 \u0111\u0103ng k\u00fd l\u00e0 VN-20580-17.<\/strong><\/p>\n<h2>Alexan l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i l\u1ecd<strong>\u00a0Alexan <\/strong>ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li>Cytarabin 50mg\/ml<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf : Dung d\u1ecbch ti\u00eam, ti\u00eam truy\u1ec1n<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-20580-17<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd 10ml<\/p>\n<p>Xu\u1ea5t x\u1ee9: Austria<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Alexan<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Cytarabin l\u00e0 m\u1ed9t trong nh\u1eefng lo\u1ea1i thu\u1ed1c ch\u00ednh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh b\u1ea1ch c\u1ea7u t\u1ee7y c\u1ea5p t\u00ednh. Cytarabin l\u00e0 m\u1ed9t ch\u1ea5t t\u01b0\u01a1ng t\u1ef1 deoxycytidine \u0111\u01b0\u1ee3c phosphoryl h\u00f3a th\u00e0nh cytosine arabinoside triphosphate (Ara-CTP) d\u01b0\u1edbi d\u1ea1ng ho\u1ea1t \u0111\u1ed9ng, c\u1ea1nh tranh v\u1edbi deoxycytidine triphosphate (dCTP) \u0111\u1ec3 \u0111\u01b0a v\u00e0o DNA. Cytarabin c\u0169ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u1ee7ng c\u1ed1 b\u1ec7nh b\u1ea1ch c\u1ea7u lymphoblastic c\u1ea5p t\u00ednh.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<h4>H\u1ea5p thu<\/h4>\n<p>Cytarabin \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh ngay sau khi k\u1ebft th\u00fac truy\u1ec1n, ti\u00eam d\u01b0\u1edbi da \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh kho\u1ea3ng 20\u201360 ph\u00fat sau ti\u00eam.<\/p>\n<h4>Ph\u00e2n b\u1ed1<\/h4>\n<p>Ph\u00e2n b\u1ed1 r\u1ea5t nhanh v\u00e0 khu\u1ebfch t\u00e1n t\u1ed1t v\u00e0o d\u1ecbch n\u00e3o t\u1ee7y.<\/p>\n<h4>Chuy\u1ec3n h\u00f3a<\/h4>\n<p>Chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu b\u1edfi pyrimidine nucleoside deaminase th\u00e0nh 1-\u03b2-D-arabinofuranosyluracil.<\/p>\n<h4>Th\u1ea3i tr\u1eeb<\/h4>\n<p>Kho\u1ea3ng 80% li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c thu h\u1ed3i qua th\u1eadn sau 24 gi\u1edd.<\/p>\n<h2>Alexan \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p><strong>Alexan Cytarabin<\/strong>\u00a0\u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb<\/p>\n<ul>\n<li>B\u1ec7nh b\u1ea1ch c\u1ea7u d\u00f2ng t\u1ee7y c\u1ea5p t\u00ednh (AML) \u1edf ng\u01b0\u1eddi l\u1edbn<\/li>\n<li>C\u00e1c b\u1ec7nh b\u1ea1ch c\u1ea7u kh\u00e1c (\u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em)<\/li>\n<\/ul>\n<figure id=\"attachment_127222\" aria-describedby=\"caption-attachment-127222\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-127222\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/alexan-dieu-tri-bach-cau-dong-hat-cap.jpg\" alt=\"Alexan \u0111i\u1ec1u tr\u1ecb b\u1ec7nh b\u1ea1ch c\u1ea7u d\u00f2ng h\u1ea1t c\u1ea5p\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/alexan-dieu-tri-bach-cau-dong-hat-cap.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/alexan-dieu-tri-bach-cau-dong-hat-cap-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/alexan-dieu-tri-bach-cau-dong-hat-cap-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/alexan-dieu-tri-bach-cau-dong-hat-cap-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-127222\" class=\"wp-caption-text\">Alexan \u0111i\u1ec1u tr\u1ecb b\u1ec7nh b\u1ea1ch c\u1ea7u d\u00f2ng h\u1ea1t c\u1ea5p<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Alexan<\/h2>\n<h4>\u0110i\u1ec1u tr\u1ecb gi\u1ea3m nh\u1eb9<\/h4>\n<p>Li\u1ec7u ph\u00e1p li\u00ean t\u1ee5c:<\/p>\n<ul>\n<li>Kh\u1edfi \u0111\u1ea7u : 2mg\/kg, ti\u00eam nhanh 1\u202fl\u1ea7n\/ng\u00e0y trong 10\u202fng\u00e0y. N\u1ebfu kh\u00f4ng \u0111\u00e1p \u1ee9ng v\u00e0 kh\u00f4ng c\u00f3 \u0111\u1ed9c t\u00ednh r\u00f5, t\u0103ng l\u00ean 4mg\/kg, duy tr\u00ec \u0111\u1ebfn khi c\u00f3 \u0111\u00e1p \u1ee9ng ho\u1eb7c c\u00f3 \u0111\u1ed9c t\u00ednh.<\/li>\n<li>Truy\u1ec1n t\u0129nh m\u1ea1ch :\u00a00,5\u20131\u202fmg\/kg\/gi\u1edd, truy\u1ec1n trong 24\u202fgi\u1edd, l\u1eb7p l\u1ea1i h\u1eb1ng ng\u00e0y.<\/li>\n<\/ul>\n<p>Li\u1ec7u ph\u00e1p ng\u1eaft qu\u00e3ng:<\/p>\n<ul>\n<li>3\u20135mg\/kg, truy\u1ec1n t\u0129nh m\u1ea1ch 1\u202fl\u1ea7n\/ng\u00e0y trong 5\u202fng\u00e0y, ngh\u1ec9 2\u20139\u202fng\u00e0y r\u1ed3i l\u1eb7p l\u1ea1i chu k\u1ef3 cho \u0111\u1ebfn khi \u0111\u00e1p \u1ee9ng ho\u1eb7c xu\u1ea5t hi\u1ec7n \u0111\u1ed9c t\u00ednh.<\/li>\n<\/ul>\n<h4>\u0110i\u1ec1u tr\u1ecb duy tr\u00ec<\/h4>\n<ul>\n<li>1mg\/kg, ti\u00eam t\u0129nh m\u1ea1ch ho\u1eb7c d\u01b0\u1edbi da, 1\u20132\u202fl\u1ea7n\/tu\u1ea7n \u0111\u1ec3 gi\u1eef \u1ed5n \u0111\u1ecbnh t\u00ecnh tr\u1ea1ng.<\/li>\n<\/ul>\n<h4>Vi\u00eam m\u00e0ng n\u00e3o do b\u1ea1ch c\u1ea7u c\u1ea5p<\/h4>\n<ul>\n<li>T\u1ed5ng li\u1ec1u kh\u00f4ng qu\u00e1\u202f100mg\/ng\u00e0y.<\/li>\n<li>Th\u01b0\u1eddng ph\u1ed1i h\u1ee3p xen k\u1ebd v\u1edbi methotrexate, theo ph\u00e1c \u0111\u1ed3 c\u1ee5 th\u1ec3 c\u1ee7a t\u1eebng b\u1ec7nh vi\u1ec7n.<\/li>\n<\/ul>\n<h4>\u0110\u1ed1i t\u01b0\u1ee3ng \u0111\u1eb7c bi\u1ec7t<\/h4>\n<ul>\n<li>Tr\u1ebb em: th\u01b0\u1eddng dung n\u1ea1p li\u1ec1u cao h\u01a1n ng\u01b0\u1eddi l\u1edbn, li\u1ec1u kh\u1edfi \u0111\u1ea7u v\u00e0 t\u0103ng li\u1ec1u \u0111\u01b0\u1ee3c t\u00ednh theo c\u00e2n n\u1eb7ng v\u00e0 \u0111\u00e1p \u1ee9ng.<\/li>\n<li>Ng\u01b0\u1eddi cao tu\u1ed5i: kh\u00f4ng ph\u1ea3i \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u c\u1ed1 \u0111\u1ecbnh, nh\u01b0ng c\u1ea7n gi\u00e1m s\u00e1t ch\u1eb7t ch\u1ebd t\u00ecnh tr\u1ea1ng huy\u1ebft h\u1ecdc \u0111\u1ec3 k\u1ecbp th\u1eddi h\u1ed7 tr\u1ee3.<\/li>\n<\/ul>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Alexan<\/h2>\n<ul>\n<li>Alexan \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam: ti\u00eam t\u0129nh m\u1ea1ch, truy\u1ec1n ho\u1eb7c ti\u00eam d\u01b0\u1edbi da.<\/li>\n<li>Pha lo\u00e3ng v\u1edbi NaCl 0,9\u202f% ho\u1eb7c Glucose 5\u202f% tr\u01b0\u1edbc khi truy\u1ec1n.<\/li>\n<li>Ti\u00eam nhanh th\u01b0\u1eddng dung n\u1ea1p t\u1ed1t h\u01a1n truy\u1ec1n li\u00ean t\u1ee5c do thu\u1ed1c b\u1ea5t ho\u1ea1t nhanh.<\/li>\n<li>Ch\u1ec9 s\u1eed d\u1ee5ng t\u1ea1i c\u01a1 s\u1edf chuy\u00ean khoa, d\u01b0\u1edbi s\u1ef1 gi\u00e1m s\u00e1t c\u1ee7a b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb ung th\u01b0.<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Alexan trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Kh\u00f4ng d\u00f9ng Alexan cho ng\u01b0\u1eddi c\u00f3 m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>Thi\u1ebfu m\u00e1u, gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh ho\u1eb7c gi\u1ea3m ti\u1ec3u c\u1ea7u n\u1eb7ng kh\u00f4ng do b\u1ec7nh \u00e1c t\u00ednh.<\/li>\n<li>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh khi c\u00f3 thai.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Alexan<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Cytarabin \u1ee9c ch\u1ebf t\u1ee7y x\u01b0\u01a1ng m\u1ea1nh, ph\u1ea3i theo d\u00f5i c\u00f4ng th\u1ee9c m\u00e1u (b\u1ea1ch c\u1ea7u, ti\u1ec3u c\u1ea7u) h\u00e0ng ng\u00e0y trong ph\u00e1c \u0111\u1ed3 t\u1ea5n c\u00f4ng v\u00e0 \u0111\u1ecbnh k\u1ef3 sau \u0111\u00f3.<\/li>\n<li>Ng\u01b0ng ho\u1eb7c gi\u1ea3m li\u1ec1u khi ti\u1ec3u c\u1ea7u d\u01b0\u1edbi\u202f50000\/mm3 ho\u1eb7c b\u1ea1ch c\u1ea7u trung t\u00ednh d\u01b0\u1edbi\u202f1000\u202f\/mm3, ch\u1ec9 t\u00e1i kh\u1edfi tr\u1ecb khi t\u1ee7y x\u01b0\u01a1ng ph\u1ee5c h\u1ed3i.<\/li>\n<li>Chu\u1ea9n b\u1ecb kh\u00e1ng sinh, truy\u1ec1n huy\u1ebft t\u01b0\u01a1ng kh\u1ed1i ti\u1ec3u c\u1ea7u v\u00e0 h\u1ed7 tr\u1ee3 ch\u0103m s\u00f3c t\u00edch c\u1ef1c cho nhi\u1ec5m khu\u1ea9n do gi\u1ea3m b\u1ea1ch c\u1ea7u h\u1ea1t v\u00e0 xu\u1ea5t huy\u1ebft th\u1ee9 ph\u00e1t.<\/li>\n<li>\u0110\u00e3 c\u00f3 s\u1ed1c ph\u1ea3n v\u1ec7 ngay sau ti\u00eam t\u0129nh m\u1ea1ch, c\u1ea7n s\u1eb5n s\u00e0ng h\u1ed3i s\u1ee9c tim ph\u1ed5i.<\/li>\n<li>\u0110\u1ed9c t\u00ednh nghi\u00eam tr\u1ecdng l\u00ean ti\u00eau h\u00f3a, th\u1ea7n kinh trung \u01b0\u01a1ng, h\u00f4 h\u1ea5p v\u00e0 da m\u1eaft; th\u1eadn tr\u1ecdng t\u1ed1i \u0111a, th\u01b0\u1eddng xuy\u00ean \u0111\u00e1nh gi\u00e1 ch\u1ee9c n\u0103ng gan, th\u1eadn v\u00e0 th\u1ea7n kinh.<\/li>\n<li>Ng\u01b0ng \u0111i\u1ec1u tr\u1ecb khi x\u1ea3y ra co gi\u1eadt, r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n n\u1eb7ng, ho\u1eb7c bi\u1ec3u hi\u1ec7n ph\u00f9 ph\u1ed5i c\u1ea5p.<\/li>\n<li>Theo d\u00f5i h\u1ed9i ch\u1ee9ng ly gi\u1ea3i kh\u1ed1i u (acid uric m\u00e1u) v\u00e0 d\u1ef1 ph\u00f2ng b\u1eb1ng thu\u1ed1c h\u1ea1 acid uric.<\/li>\n<li>Tr\u00e1nh d\u00f9ng vaccin s\u1ed1ng, c\u00f3 th\u1ec3 d\u00f9ng vaccin b\u1ea5t ho\u1ea1t nh\u01b0ng \u0111\u00e1p \u1ee9ng mi\u1ec5n d\u1ecbch c\u00f3 th\u1ec3 gi\u1ea3m.<\/li>\n<li>Cytarabin c\u00f3 th\u1ec3 g\u00e2y \u0111\u1ed9t bi\u1ebfn v\u00e0 \u0111\u1ed9c t\u00ednh sinh s\u1ea3n.<\/li>\n<li>Ch\u1ec9 b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 c\u00f3 kinh nghi\u1ec7m m\u1edbi \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh v\u00e0 gi\u00e1m s\u00e1t li\u1ec7u tr\u00ecnh.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<h4>Hay g\u1eb7p<\/h4>\n<ul>\n<li>H\u1ec7 th\u1ed1ng m\u00e1u &amp; b\u1ea1ch huy\u1ebft: suy t\u1ee7y x\u01b0\u01a1ng, gi\u1ea3m ti\u1ec3u c\u1ea7u, thi\u1ebfu m\u00e1u, thi\u1ebfu m\u00e1u nguy\u00ean h\u1ed3ng c\u1ea7u kh\u1ed5ng l\u1ed3, gi\u1ea3m b\u1ea1ch c\u1ea7u h\u1ea1t, gi\u1ea3m t\u1ebf b\u00e0o h\u1ed3ng c\u1ea7u l\u01b0\u1edbi<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n: nhi\u1ec5m khu\u1ea9n huy\u1ebft, vi\u00eam ph\u1ed5i, nhi\u1ec5m tr\u00f9ng<\/li>\n<li>Gan m\u1eadt: b\u1ea5t th\u01b0\u1eddng ch\u1ee9c n\u0103ng gan (t\u0103ng men gan)<\/li>\n<\/ul>\n<h4>Th\u01b0\u1eddng g\u1eb7p<\/h4>\n<ul>\n<li>Chuy\u1ec3n h\u00f3a v\u00e0 dinh d\u01b0\u1ee1ng: ch\u00e1n \u0103n, t\u0103ng acid uric m\u00e1u<\/li>\n<li>H\u1ec7 th\u1ea7n kinh: \u0111\u1ed9c t\u00ednh th\u1ea7n kinh trung \u01b0\u01a1ng (suy gi\u1ea3m nh\u1eadn th\u1ee9c, lo\u1ea1n v\u1eadn ng\u00f4n, gi\u1eadt c\u1ea7u m\u1eaft)<\/li>\n<li>M\u1eaft: vi\u00eam k\u1ebft m\u1ea1c xu\u1ea5t huy\u1ebft c\u00f3 h\u1ed3i ph\u1ee5c (s\u1ee3 \u00e1nh s\u00e1ng, n\u00f3ng r\u00e1t, r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c, ch\u1ea3y n\u01b0\u1edbc m\u1eaft), vi\u00eam gi\u00e1c m\u1ea1c<\/li>\n<li>Ti\u00eau h\u00f3a: kh\u00f3 nu\u1ed1t, \u0111au b\u1ee5ng, bu\u1ed3n n\u00f4n, n\u00f4n, ti\u00eau ch\u1ea3y, vi\u00eam ho\u1eb7c lo\u00e9t \u0111\u01b0\u1eddng ti\u00eau h\u00f3a\/h\u1eadu m\u00f4n<\/li>\n<li>Gan m\u1eadt: men gan t\u0103ng (h\u1ed3i ph\u1ee5c)<\/li>\n<li>Da &amp; m\u00f4 d\u01b0\u1edbi da: ban \u0111\u1ecf, ph\u1ecfng r\u1ed9p, m\u00e0y \u0111ay, vi\u00eam m\u1ea1ch, r\u1ee5ng l\u00f4ng t\u00f3c<\/li>\n<li>To\u00e0n th\u00e2n &amp; t\u1ea1i ch\u1ed7 ti\u00eam: s\u1ed1t, vi\u00eam t\u0129nh m\u1ea1ch huy\u1ebft kh\u1ed1i t\u1ea1i ch\u1ed7 ti\u00eam<\/li>\n<\/ul>\n<h4>\u00cdt g\u1eb7p<\/h4>\n<ul>\n<li>Da v\u00e0 m\u00f4 d\u01b0\u1edbi da: t\u00e0n nhang, lo\u00e9t da, m\u1ea9n ng\u1ee9a, \u0111au b\u1ecfng \u1edf l\u00f2ng b\u00e0n tay v\u00e0 b\u00e0n ch\u00e2n<\/li>\n<li>Ti\u00eau h\u00f3a: vi\u00eam th\u1ef1c qu\u1ea3n, lo\u00e9t th\u1ef1c qu\u1ea3n, ch\u01b0\u1edbng kh\u00ed, vi\u00eam k\u1ebft tr\u00e0ng ho\u1ea1i t\u1eed, vi\u00eam ph\u00fac m\u1ea1c<\/li>\n<li>H\u00f4 h\u1ea5p: vi\u00eam ph\u1ed5i, kh\u00f3 th\u1edf, \u0111au h\u1ecdng<\/li>\n<li>Tim: vi\u00eam m\u00e0ng ngo\u00e0i tim<\/li>\n<li>C\u01a1 x\u01b0\u01a1ng: \u0111au c\u01a1, \u0111au x\u01b0\u01a1ng<\/li>\n<li>Th\u1eadn v\u00e0 ti\u1ebft ni\u1ec7u: r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng th\u1eadn, b\u00ed ti\u1ec3u<\/li>\n<\/ul>\n<h4>Hi\u1ebfm g\u1eb7p<\/h4>\n<ul>\n<li>H\u1ec7 th\u1ea7n kinh ngo\u1ea1i bi\u00ean: vi\u00eam d\u00e2y th\u1ea7n kinh, neuropathy ngo\u1ea1i bi\u00ean<\/li>\n<li>Tim: lo\u1ea1n nh\u1ecbp tim<\/li>\n<li>Da v\u00e0 m\u00f4 d\u01b0\u1edbi da: vi\u00eam c\u1ea5u tr\u00fac da do th\u00e2m nhi\u1ec5m b\u1ea1ch c\u1ea7u trung t\u00ednh v\u00e0o tuy\u1ebfn m\u1ed3 h\u00f4i<\/li>\n<\/ul>\n<h4>R\u1ea5t hi\u1ebfm g\u1eb7p<\/h4>\n<ul>\n<li>H\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng: co gi\u1eadt, h\u00f4n m\u00ea<\/li>\n<li>Tim: s\u1ed1c ph\u1ea3n v\u1ec7 d\u1eabn \u0111\u1ebfn ng\u1eebng tim ph\u1ed5i<\/li>\n<\/ul>\n<h4>Ch\u01b0a x\u00e1c \u0111\u1ecbnh t\u1ea7n su\u1ea5t<\/h4>\n<ul>\n<li>Nhi\u1ec5m khu\u1ea9n v\u00e0 k\u00fd sinh tr\u00f9ng: vi\u00eam m\u00f4 t\u1ebf b\u00e0o t\u1ea1i v\u1ecb tr\u00ed ti\u00eam, \u00e1p xe gan<\/li>\n<li>H\u1ec7 th\u1ea7n kinh: \u0111\u1ed9c th\u1ea7n kinh, ch\u00f3ng m\u1eb7t, nh\u1ee9c \u0111\u1ea7u<\/li>\n<li>Gan m\u1eadt: v\u00e0ng da<\/li>\n<li>Sinh s\u1ea3n: m\u1ea5t kinh ho\u1eb7c kh\u00f4ng c\u00f3 tinh tr\u00f9ng<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Tr\u00e1nh s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi flucytosin v\u1edbi cytarabin do l\u00e0m m\u1ea5t hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb c\u1ee7a flucytosin.<\/li>\n<li>Theo d\u00f5i n\u1ed3ng \u0111\u1ed9 digoxin huy\u1ebft t\u01b0\u01a1ng khi d\u00f9ng beta\u2011acetyldigoxin k\u1ebft h\u1ee3p v\u1edbi ph\u00e1c \u0111\u1ed3 h\u00f3a tr\u1ecb bao g\u1ed3m cyclophosphamid, vincristin, prednison k\u00e8m ho\u1eb7c kh\u00f4ng k\u00e8m cytarabin v\u00e0 procarbazin v\u00ec g\u00e2y gi\u1ea3m c\u00f3 h\u1ed3i ph\u1ee5c n\u1ed3ng \u0111\u1ed9 digoxin v\u00e0 b\u00e0i ti\u1ebft glycosid qua th\u1eadn, c\u00f3 th\u1ec3 thay b\u1eb1ng digitoxin.<\/li>\n<li>Th\u1eadn tr\u1ecdng khi d\u00f9ng gentamicin c\u00f9ng cytarabin v\u00ec in\u202fvitro cho th\u1ea5y cytarabin c\u00f3 th\u1ec3 \u0111\u1ed1i kh\u00e1ng t\u00e1c d\u1ee5ng kh\u00e1ng khu\u1ea9n c\u1ee7a gentamicin tr\u00ean ch\u1ee7ng\u202fK.\u202fpneumoniae v\u00e0 c\u1ea7n \u0111\u00e1nh gi\u00e1 l\u1ea1i ph\u00e1c \u0111\u1ed3 kh\u00e1ng khu\u1ea9n n\u1ebfu \u0111\u00e1p \u1ee9ng kh\u00f4ng xu\u1ea5t hi\u1ec7n s\u1edbm.<\/li>\n<li>Ph\u00e1c \u0111\u1ed3 li\u1ec1u cao cytarabin ph\u1ed1i h\u1ee3p v\u1edbi daunorubicin v\u00e0 asparaginase tr\u00ean b\u1ec7nh nh\u00e2n AML c\u00f3 nguy c\u01a1 g\u1eb7p b\u1ec7nh th\u1ea7n kinh c\u1ea3m gi\u00e1c v\u00e0 v\u1eadn \u0111\u1ed9ng ngo\u1ea1i bi\u00ean.<\/li>\n<li>T\u0103ng nguy c\u01a1 \u0111\u1ed9c t\u00ednh th\u1ea7n kinh trung \u01b0\u01a1ng khi d\u00f9ng k\u1ebft h\u1ee3p cytarabin truy\u1ec1n t\u0129nh m\u1ea1ch li\u1ec1u cao v\u1edbi x\u1ea1 tr\u1ecb ho\u1eb7c c\u00e1c li\u1ec7u ph\u00e1p g\u00e2y \u0111\u1ed9c th\u1ea7n kinh trung \u01b0\u01a1ng kh\u00e1c.<\/li>\n<li>Cytarabin ti\u00eam t\u0129nh m\u1ea1ch d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi methotrexat ti\u00eam n\u1ed9i n\u00e3o th\u1ea5t c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 t\u00e1c d\u1ee5ng c\u00f3 h\u1ea1i nghi\u00eam tr\u1ecdng li\u00ean quan \u0111\u1ebfn th\u1ea7n kinh nh\u01b0 \u0111au \u0111\u1ea7u, t\u00ea li\u1ec7t, h\u00f4n m\u00ea v\u00e0 h\u1ed9i ch\u1ee9ng gi\u1ed1ng \u0111\u1ed9t qu\u1ef5.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Kh\u00f4ng d\u00f9ng thu\u1ed1c Alexan cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa.<\/p>\n<p>Nam v\u00e0 n\u1eef trong \u0111\u1ed9 tu\u1ed5i sinh s\u1ea3n ph\u1ea3i d\u00f9ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai hi\u1ec7u qu\u1ea3 trong v\u00e0 6\u202fth\u00e1ng sau \u0111i\u1ec1u tr\u1ecb<\/p>\n<h3>Kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c Alexan kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>B\u00e1o ngay v\u1edbi b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb v\u00e0 \u0111\u1ebfn c\u01a1 s\u1edf y t\u1ebf g\u1ea7n nh\u1ea5t \u0111\u1ec3 ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng k\u1ecbp th\u1eddi.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>\u0110\u1ec3 thu\u1ed1c Alexan tr\u00e1nh xa t\u1ea7m tay tr\u1ebb em.<\/p>\n<p>B\u1ea3o qu\u1ea3n thu\u1ed1c \u1edf nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30 \u0111\u1ed9 C, tr\u00e1nh \u00e1nh n\u1eafng tr\u1ef1c ti\u1ebfp t\u1eeb m\u1eb7t tr\u1eddi.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 xem th\u00eam m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m kh\u00e1c t\u1ea1i nh\u00e0 thu\u1ed1c c\u1ee7a ch\u00fang t\u00f4i c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/winduza\/\">WINDUZA<\/a> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho b\u1ec7nh nh\u00e2n tr\u01b0\u1edfng th\u00e0nh kh\u00f4ng ph\u00f9 h\u1ee3p v\u1edbi ph\u01b0\u01a1ng ph\u00e1p c\u1ea5y gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c t\u1ea1o m\u00e1u trong h\u1ed9i ch\u1ee9ng lo\u1ea1n s\u1ea3n t\u1ee7y, b\u1ec7nh b\u1ea1ch c\u1ea7u d\u00f2ng t\u1ee7y m\u1ea1n t\u00ednh v\u00e0 c\u1ea5p t\u00ednh.<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/decitabine-for-injection-50mg-per-vial\/\">Thu\u1ed1c Decitabine for injection 50mg per vial<\/a> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong h\u1ed9i ch\u1ee9ng r\u1ed1i lo\u1ea1n sinh t\u1ee7y v\u00e0 b\u1ec7nh b\u1ea1ch c\u1ea7u c\u1ea5p d\u00f2ng t\u1ee7y.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>1. H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng \u0111\u01b0\u1ee3c C\u1ee5c qu\u1ea3n l\u00fd ph\u00ea duy\u1ec7t. Xem ngay <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/alexan-huong-dan-su-dung.pdf\">T\u1ea0I \u0110\u00c2Y<\/a>.<\/p>\n<p>2. Meixian Huang, Takeshi Inukai, Kunio Miyake, Yoichi Tanaka, Keiko Kagami, Masako Abe, Hiroaki Goto, Masayoshi Minegishi, Shotaro Iwamoto, Eiji Sugihara, Atsushi Watanabe, Shinpei Somazu, Tamao Shinohara 1, Hiroko Oshiro, Koshi Akahane, Kumiko Goi, Kanji Sugita (2018), Clofarabine exerts antileukemic activity against cytarabine\u2010resistant B\u2010cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression. Truy c\u1eadp ng\u00e0y 15\/07\/2025 t\u1eeb <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5911575\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5911575\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Alexan ch\u1ee9a ho\u1ea1t ch\u1ea5t Cytarabin h\u00e0m l\u01b0\u1ee3ng 50mg\/ml,\u00a0\u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb\u00a0b\u1ec7nh b\u1ea1ch c\u1ea7u d\u00f2ng t\u1ee7y c\u1ea5p t\u00ednh \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 c\u00e1c b\u1ec7nh b\u1ea1ch c\u1ea7u kh\u00e1c \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em.<\/p>\n","protected":false},"author":1,"featured_media":127223,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-127220","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/127220","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=127220"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/127223"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=127220"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=127220"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=127220"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}