{"id":127108,"date":"2025-07-15T11:16:24","date_gmt":"2025-07-15T04:16:24","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=127108"},"modified":"2025-12-23T10:42:26","modified_gmt":"2025-12-23T03:42:26","slug":"anepzil-5mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/anepzil-5mg\/","title":{"rendered":"Anepzil 5mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Anepzil 5mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Chi nh\u00e1nh c\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Agimexpharm &#8211; Nh\u00e0 m\u00e1y s\u1ea3n xu\u1ea5t D\u01b0\u1ee3c ph\u1ea9m Agimexpharm, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110257423.<\/strong><\/p>\n<h2>Anepzil 5mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Anepzil 5mg <\/strong>c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t: <strong>Donepezil<\/strong> hydrochloride 5mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: V\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110257423<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u00f4\u0323p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_127115\" aria-describedby=\"caption-attachment-127115\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-127115\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Anepzil-5mg-1.jpg\" alt=\"Anepzil 5mg suy gi\u1ea3m tr\u00ed nh\u1edb \u1edf ng\u01b0\u1eddi m\u1eafc b\u1ec7nh Alzheimer\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Anepzil-5mg-1.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Anepzil-5mg-1-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Anepzil-5mg-1-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Anepzil-5mg-1-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-127115\" class=\"wp-caption-text\">Anepzil 5mg suy gi\u1ea3m tr\u00ed nh\u1edb \u1edf ng\u01b0\u1eddi m\u1eafc b\u1ec7nh Alzheimer<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Anepzil 5mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<ul>\n<li>B\u1ec7nh Alzheimer \u0111\u01b0\u1ee3c \u0111\u1eb7c tr\u01b0ng b\u1edfi s\u1ef1 thi\u1ebfu h\u1ee5t ch\u1ea5t d\u1eabn truy\u1ec1n th\u1ea7n kinh acetylcholine trong n\u00e3o b\u1ed9, m\u1ed9t ch\u1ea5t \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong qu\u00e1 tr\u00ecnh ghi nh\u1edb v\u00e0 h\u1ecdc t\u1eadp.<\/li>\n<li>Donepezil ho\u1ea1t \u0111\u1ed9ng theo c\u01a1 ch\u1ebf \u1ee9c ch\u1ebf thu\u1eadn ngh\u1ecbch v\u00e0 ch\u1ecdn l\u1ecdc enzym acetylcholinesterase (AChE). Enzym n\u00e0y c\u00f3 nhi\u1ec7m v\u1ee5 ph\u00e2n h\u1ee7y acetylcholine t\u1ea1i c\u00e1c khe synap th\u1ea7n kinh. B\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf AChE, Donepezil l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 acetylcholine kh\u1ea3 d\u1ee5ng trong n\u00e3o, t\u1eeb \u0111\u00f3 t\u0103ng c\u01b0\u1eddng d\u1eabn truy\u1ec1n t\u00edn hi\u1ec7u cholinergic v\u00e0 c\u1ea3i thi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh.<\/li>\n<\/ul>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu: Donepezil \u0111\u01b0\u1ee3c h\u1ea5p thu t\u1ed1t qua \u0111\u01b0\u1eddng u\u1ed1ng, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau kho\u1ea3ng 3-4 gi\u1edd.<\/li>\n<li>Ph\u00e2n b\u1ed1: Kho\u1ea3ng 95% Donepezil li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng.<\/li>\n<li>Chuy\u1ec3n h\u00f3a: Thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a m\u1ea1nh m\u1ebd qua gan, ch\u1ee7 y\u1ebfu qua h\u1ec7 th\u1ed1ng cytochrom P450 (isoenzym CYP3A4 v\u00e0 CYP2D6).<\/li>\n<li>Th\u1ea3i tr\u1eeb: Thu\u1ed1c \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u. Th\u1eddi gian b\u00e1n th\u1ea3i d\u00e0i, kho\u1ea3ng 70 gi\u1edd, cho ph\u00e9p s\u1eed d\u1ee5ng li\u1ec1u duy nh\u1ea5t m\u1ed7i ng\u00e0y.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Anepzil 5mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<ul>\n<li>Thu\u1ed1c Anepzil 5mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng cho b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc b\u1ec7nh Alzheimer m\u1ee9c \u0111\u1ed9 nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh.<\/li>\n<li>M\u1ed9t s\u1ed1 h\u01b0\u1edbng d\u1eabn \u0111i\u1ec1u tr\u1ecb qu\u1ed1c t\u1ebf c\u0169ng xem x\u00e9t vi\u1ec7c s\u1eed d\u1ee5ng Donepezil cho giai \u0111o\u1ea1n n\u1eb7ng c\u1ee7a b\u1ec7nh, tuy nhi\u00ean quy\u1ebft \u0111\u1ecbnh n\u00e0y c\u1ea7n \u0111\u01b0\u1ee3c b\u00e1c s\u0129 chuy\u00ean khoa c\u00e2n nh\u1eafc k\u1ef9 l\u01b0\u1ee1ng.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Anepzil 5mg<\/h2>\n<ul>\n<li>Li\u1ec1u kh\u1edfi \u0111\u1ea7u v\u00e0 duy tr\u00ec: U\u1ed1ng 5mg\/l\u1ea7n\/ng\u00e0y.<\/li>\n<li>Li\u1ec1u 5mg n\u00ean \u0111\u01b0\u1ee3c duy tr\u00ec trong \u00edt nh\u1ea5t 1 th\u00e1ng \u0111\u1ec3 \u0111\u00e1nh gi\u00e1 \u0111\u00e1p \u1ee9ng l\u00e2m s\u00e0ng ban \u0111\u1ea7u.<\/li>\n<li>Sau 4-6 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb, n\u1ebfu b\u1ec7nh nh\u00e2n dung n\u1ea1p t\u1ed1t, c\u00f3 th\u1ec3 xem x\u00e9t t\u0103ng li\u1ec1u l\u00ean 10mg\/l\u1ea7n\/ng\u00e0y \u0111\u1ec3 t\u1ed1i \u01b0u h\u00f3a hi\u1ec7u qu\u1ea3.<\/li>\n<\/ul>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Anepzil 5mg<\/h2>\n<ul>\n<li>D\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng.<\/li>\n<li>N\u00ean u\u1ed1ng thu\u1ed1c v\u00e0o bu\u1ed5i t\u1ed1i, ngay tr\u01b0\u1edbc khi \u0111i ng\u1ee7.<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Anepzil 5mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>B\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed m\u1eabn c\u1ea3m v\u1edbi Donepezil hydrochloride, c\u00e1c d\u1eabn ch\u1ea5t c\u1ee7a piperidin, ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Anepzil 5mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>C\u1ea7n th\u1eadn tr\u1ecdng v\u1edbi b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed hen suy\u1ec5n ho\u1eb7c b\u1ec7nh ph\u1ed5i t\u1eafc ngh\u1ebdn m\u1ea1n t\u00ednh (COPD).<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>C\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n th\u01b0\u1eddng nh\u1eb9 v\u00e0 tho\u00e1ng qua. Ph\u1ed5 bi\u1ebfn nh\u1ea5t bao g\u1ed3m:<\/p>\n<ul>\n<li>R\u1ea5t ph\u1ed5 bi\u1ebfn (\u22651\/10): Ti\u00eau ch\u1ea3y, bu\u1ed3n n\u00f4n, \u0111au \u0111\u1ea7u.<\/li>\n<li>Ph\u1ed5 bi\u1ebfn (\u22651\/100 \u0111\u1ebfn &lt;1\/10): C\u1ea3m l\u1ea1nh th\u00f4ng th\u01b0\u1eddng, ch\u00e1n \u0103n, \u1ea3o gi\u00e1c, k\u00edch \u0111\u1ed9ng, h\u00e0nh vi hung h\u0103ng, m\u1ea5t ng\u1ee7, ng\u1ea5t, ch\u00f3ng m\u1eb7t, n\u00f4n m\u1eeda, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a, ph\u00e1t ban, ng\u1ee9a, co c\u1ee9ng c\u01a1, ti\u1ec3u kh\u00f4ng t\u1ef1 ch\u1ee7, m\u1ec7t m\u1ecfi, \u0111au.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Donepezil v\u00e0 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a n\u00f3 kh\u00f4ng \u1ee9c ch\u1ebf s\u1ef1 chuy\u1ec3n h\u00f3a c\u1ee7a aheophylin, warfarin, cimetidin ho\u1eb7c digoxin.<\/li>\n<li>C\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf CYP3A4 (nh\u01b0 ketoconazol, itraconazol) v\u00e0 CYP2D6 (nh\u01b0 quinidin, fluoxetin) c\u00f3 th\u1ec3 \u1ee9c ch\u1ebf chuy\u1ec3n h\u00f3a c\u1ee7a Donepezil, l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 thu\u1ed1c.<\/li>\n<li>C\u00e1c thu\u1ed1c c\u1ea3m \u1ee9ng CYP3A4 v\u00e0 CYP2D6 (nh\u01b0 rifampicin, phenytoin, carbamazepin, r\u01b0\u1ee3u) c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 Donepezil.<\/li>\n<li>Donepezil c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn t\u00e1c d\u1ee5ng c\u1ee7a c\u00e1c thu\u1ed1c kh\u00e1ng cholinergic.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<ul>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai: Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u l\u00e2m s\u00e0ng \u0111\u1ea7y \u0111\u1ee7. Kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng thu\u1ed1c trong thai k\u1ef3 tr\u1eeb khi l\u1ee3i \u00edch cho m\u1eb9 v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1 ti\u1ec1m \u1ea9n cho thai nhi.<\/li>\n<li>Ph\u1ee5 n\u1eef cho con b\u00fa: Ch\u01b0a r\u00f5 Donepezil c\u00f3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 hay kh\u00f4ng. Kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>B\u1ec7nh Alzheimer c\u00f3 th\u1ec3 l\u00e0m suy gi\u1ea3m kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c. B\u00e1c s\u0129 c\u1ea7n \u0111\u00e1nh gi\u00e1 th\u01b0\u1eddng xuy\u00ean kh\u1ea3 n\u0103ng ti\u1ebfp t\u1ee5c th\u1ef1c hi\u1ec7n c\u00e1c c\u00f4ng vi\u1ec7c n\u00e0y c\u1ee7a b\u1ec7nh nh\u00e2n.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<ul>\n<li>Tri\u1ec7u ch\u1ee9ng: Qu\u00e1 li\u1ec1u c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf cholinesterase c\u00f3 th\u1ec3 g\u00e2y ra h\u1ed9i ch\u1ee9ng c\u01b0\u1eddng cholinergic \u0111\u1eb7c tr\u01b0ng b\u1edfi bu\u1ed3n n\u00f4n, n\u00f4n, ti\u1ebft n\u01b0\u1edbc b\u1ecdt, \u0111\u1ed5 m\u1ed3 h\u00f4i, nh\u1ecbp tim ch\u1eadm, h\u1ea1 huy\u1ebft \u00e1p, suy h\u00f4 h\u1ea5p, tr\u1ee5y tu\u1ea7n ho\u00e0n v\u00e0 co gi\u1eadt.<\/li>\n<li>X\u1eed tr\u00ed: C\u1ea7n \u00e1p d\u1ee5ng c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 to\u00e0n th\u00e2n. C\u00f3 th\u1ec3 s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c kh\u00e1ng cholinergic th\u1ebf h\u1ec7 th\u1ee9 ba nh\u01b0 atropin l\u00e0m thu\u1ed1c gi\u1ea3i \u0111\u1ed9c.<\/li>\n<\/ul>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Anepzil 5mg<\/h2>\n<p><a href=\"https:\/\/vnras.com\/drug\/donepezil-odt-10\/\">Donepezil ODT 10 <\/a>\u00a0ch\u1ee9a Donepezil HCl 10mg, \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean n\u00e9n r\u00e3 trong mi\u1ec7ng (ODT), thu\u1eadn ti\u1ec7n cho b\u1ec7nh nh\u00e2n kh\u00f3 nu\u1ed1t.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Nan Zhang, Marc L Gordon. Clinical efficacy and safety of donepezil in the treatment of Alzheimer&#8217;s disease in Chinese patients, truy c\u1eadp ng\u00e0y 15 th\u00e1ng 07 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30349215\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30349215\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Anepzil 5mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Chi nh\u00e1nh c\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Agimexpharm &#8211; Nh\u00e0 m\u00e1y s\u1ea3n xu\u1ea5t D\u01b0\u1ee3c ph\u1ea9m Agimexpharm, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110257423, \u0111i\u1ec1u tr\u1ecb Alzheimer m\u1ee9c \u0111\u1ed9 nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh.<\/p>\n","protected":false},"author":1,"featured_media":127116,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-127108","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/127108","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=127108"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/127116"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=127108"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=127108"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=127108"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}