{"id":126952,"date":"2025-07-14T11:09:01","date_gmt":"2025-07-14T04:09:01","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=126952"},"modified":"2025-12-23T10:41:17","modified_gmt":"2025-12-23T03:41:17","slug":"bactrim-400-80mg-5ml","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/bactrim-400-80mg-5ml\/","title":{"rendered":"Bactrim\u00ae 400\/80mg\/5ml"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Bactrim\u00ae 400\/80mg\/5ml \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty F. Hoffmann-La Roche., Ltd, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 3142\/QLD-KD.<\/strong><\/p>\n<h2>Bactrim\u00ae 400\/80mg\/5ml l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i 5ml dung d\u1ecbch <strong>Bactrim\u00ae 400\/80mg\/5ml<\/strong> ch\u1ee9a:<\/p>\n<ul>\n<li><strong>Sulfamethoxazole<\/strong>: 400 mg<\/li>\n<li>Trimethoprim: 80 mg<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 3142\/QLD-KD<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 \u1ed1ng x 5ml<\/p>\n<p>Xu\u1ea5t x\u1ee9: Th\u1ee5y S\u0129<\/p>\n<figure id=\"attachment_126954\" aria-describedby=\"caption-attachment-126954\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-126954\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Bactrim-40080mg5ml-1.jpg\" alt=\"Bactrim\u00ae 400\/80mg\/5ml \u0111i\u1ec1u tr\u1ecb \u0111\u1ee3t c\u1ea5p vi\u00eam ph\u1ebf qu\u1ea3n m\u1ea1n\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Bactrim-40080mg5ml-1.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Bactrim-40080mg5ml-1-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Bactrim-40080mg5ml-1-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Bactrim-40080mg5ml-1-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-126954\" class=\"wp-caption-text\">Bactrim\u00ae 400\/80mg\/5ml \u0111i\u1ec1u tr\u1ecb \u0111\u1ee3t c\u1ea5p vi\u00eam ph\u1ebf qu\u1ea3n m\u1ea1n<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Bactrim\u00ae 400\/80mg\/5ml<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Bactrim\u00ae \u1ee9c ch\u1ebf hai giai \u0111o\u1ea1n li\u00ean ti\u1ebfp trong qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p acid folic c\u1ee7a vi khu\u1ea9n, m\u1ed9t ch\u1ea5t c\u1ea7n thi\u1ebft cho s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a ch\u00fang, t\u1eeb \u0111\u00f3 mang l\u1ea1i t\u00e1c d\u1ee5ng di\u1ec7t khu\u1ea9n.<\/p>\n<ul>\n<li>Sulfamethoxazole: Ng\u0103n ch\u1eb7n vi khu\u1ea9n t\u1ed5ng h\u1ee3p acid dihydrofolic.<\/li>\n<li>Trimethoprim: \u1ee8c ch\u1ebf enzym chuy\u1ec3n h\u00f3a acid dihydrofolic th\u00e0nh d\u1ea1ng ho\u1ea1t \u0111\u1ed9ng.<\/li>\n<\/ul>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu v\u00e0 ph\u00e2n b\u1ed1: Sau khi d\u00f9ng, thu\u1ed1c \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh v\u00e0 ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i v\u00e0o c\u00e1c m\u00f4 v\u00e0 d\u1ecbch trong c\u01a1 th\u1ec3, bao g\u1ed3m c\u1ea3 d\u1ecbch n\u00e3o t\u1ee7y.<\/li>\n<li>Chuy\u1ec3n h\u00f3a v\u00e0 th\u1ea3i tr\u1eeb: Thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a \u1edf gan v\u00e0 th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua th\u1eadn. Th\u1eddi gian b\u00e1n th\u1ea3i c\u1ee7a sulfamethoxazole l\u00e0 9-11 gi\u1edd v\u00e0 c\u1ee7a trimethoprim l\u00e0 8,6-17 gi\u1edd \u1edf ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Bactrim\u00ae 400\/80mg\/5ml \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Bactrim\u00ae \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em tr\u00ean hai th\u00e1ng tu\u1ed5i trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m khu\u1ea9n do vi khu\u1ea9n nh\u1ea1y c\u1ea3m:<\/p>\n<ul>\n<li>Vi\u00eam ph\u1ed5i do <em>Pneumocystis jirovecii<\/em> (PCP): \u0110i\u1ec1u tr\u1ecb v\u00e0 d\u1ef1 ph\u00f2ng, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n suy gi\u1ea3m mi\u1ec5n d\u1ecbch.<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u: \u0110i\u1ec1u tr\u1ecb c\u00e1c tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng ho\u1eb7c ph\u1ee9c t\u1ea1p nh\u01b0 vi\u00eam tuy\u1ebfn ti\u1ec1n li\u1ec7t, nhi\u1ec5m tr\u00f9ng t\u00e1i ph\u00e1t.<\/li>\n<li>\u0110\u1ee3t c\u1ea5p vi\u00eam ph\u1ebf qu\u1ea3n m\u1ea1n t\u00ednh: \u0110\u1eb7c bi\u1ec7t do <em> influenzae<\/em> ho\u1eb7c <em>S. pneumoniae<\/em>.<\/li>\n<li>L\u1ef5 tr\u1ef1c khu\u1ea9n: Do c\u00e1c ch\u1ee7ng <em>Shigella<\/em> nh\u1ea1y c\u1ea3m.<\/li>\n<li>C\u00e1c nhi\u1ec5m khu\u1ea9n kh\u00e1c: Nh\u01b0 vi\u00eam tai gi\u1eefa c\u1ea5p t\u00ednh, nhi\u1ec5m Nocardia, Toxoplasmosis khi c\u00f3 b\u1eb1ng ch\u1ee9ng vi khu\u1ea9n nh\u1ea1y c\u1ea3m.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Bactrim\u00ae 400\/80mg\/5ml<\/h2>\n<p><strong>Bactrim\u00ae li\u1ec1u d\u00f9ng<\/strong> \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh t\u00f9y thu\u1ed9c v\u00e0o \u0111\u1ed9 tu\u1ed5i, c\u00e2n n\u1eb7ng, ch\u1ee9c n\u0103ng th\u1eadn v\u00e0 m\u1ee9c \u0111\u1ed9 n\u1eb7ng c\u1ee7a nhi\u1ec5m khu\u1ea9n. Li\u1ec1u d\u00f9ng tham kh\u1ea3o (truy\u1ec1n t\u0129nh m\u1ea1ch):<\/p>\n<ul>\n<li>Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em &gt; 12 tu\u1ed5i: 10ml (2 \u1ed1ng)\/l\u1ea7n, m\u1ed7i 12 gi\u1edd. C\u00f3 th\u1ec3 t\u0103ng l\u00ean 15ml\/l\u1ea7n m\u1ed7i 12 gi\u1edd \u0111\u1ed1i v\u1edbi nhi\u1ec5m khu\u1ea9n n\u1eb7ng.<\/li>\n<li>Tr\u1ebb em 6 &#8211; 12 tu\u1ed5i: 5ml\/l\u1ea7n, m\u1ed7i 12 gi\u1edd.<\/li>\n<li>Tr\u1ebb em 6 th\u00e1ng &#8211; 5 tu\u1ed5i: 2.5ml\/l\u1ea7n, m\u1ed7i 12 gi\u1edd.<\/li>\n<li>Tr\u1ebb em 6 tu\u1ea7n &#8211; 5 th\u00e1ng: 1.25ml\/l\u1ea7n, m\u1ed7i 12 gi\u1edd.<\/li>\n<li>B\u1ec7nh nh\u00e2n suy th\u1eadn: C\u1ea7n gi\u1ea3m li\u1ec1u theo \u0111\u1ed9 thanh th\u1ea3i creatinin. Kh\u00f4ng khuy\u1ebfn c\u00e1o cho b\u1ec7nh nh\u00e2n c\u00f3 ClCr &lt; 15 ml\/ph\u00fat.<\/li>\n<\/ul>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Bactrim\u00ae 400\/80mg\/5ml<\/h2>\n<ul>\n<li>Thu\u1ed1c ch\u1ec9 d\u00f9ng qua \u0111\u01b0\u1eddng truy\u1ec1n t\u0129nh m\u1ea1ch, tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng ti\u00eam b\u1eafp hay ti\u00eam bolus t\u0129nh m\u1ea1ch.<\/li>\n<li>Pha lo\u00e3ng tr\u01b0\u1edbc khi d\u00f9ng: M\u1ed7i 5ml thu\u1ed1c c\u1ea7n \u0111\u01b0\u1ee3c pha lo\u00e3ng v\u1edbi 125ml dung d\u1ecbch Dextrose 5% (D5W). Dung d\u1ecbch sau khi pha ph\u1ea3i \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong v\u00f2ng 6 gi\u1edd v\u00e0 kh\u00f4ng b\u1ea3o qu\u1ea3n l\u1ea1nh.<\/li>\n<li>Truy\u1ec1n t\u0129nh m\u1ea1ch ch\u1eadm trong kho\u1ea3ng 60-90 ph\u00fat.<\/li>\n<li>C\u1ea7n \u0111\u1ea3m b\u1ea3o b\u1ec7nh nh\u00e2n u\u1ed1ng \u0111\u1ee7 n\u01b0\u1edbc trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 ph\u00f2ng ng\u1eeba nguy c\u01a1 t\u1ea1o s\u1ecfi th\u1eadn.<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Bactrim\u00ae 400\/80mg\/5ml trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>B\u1ec7nh nh\u00e2n t\u1eebng b\u1ecb d\u1ecb \u1ee9ng v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o l\u00e0 trimethoprim ho\u1eb7c sulfonamide.<\/li>\n<li>B\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed gi\u1ea3m ti\u1ec3u c\u1ea7u do thu\u1ed1c ho\u1eb7c thi\u1ebfu m\u00e1u h\u1ed3ng c\u1ea7u to do thi\u1ebfu folate.<\/li>\n<li>Tr\u1ebb s\u01a1 sinh d\u01b0\u1edbi hai th\u00e1ng tu\u1ed5i.<\/li>\n<li>B\u1ec7nh nh\u00e2n suy gan ho\u1eb7c suy th\u1eadn n\u1eb7ng.<\/li>\n<li>\u0110ang d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi thu\u1ed1c Dofetilide.<\/li>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai ho\u1eb7c \u0111ang cho con b\u00fa.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Bactrim\u00ae 400\/80mg\/5ml<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>C\u1ea7n theo d\u00f5i c\u00f4ng th\u1ee9c m\u00e1u, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n \u0111i\u1ec1u tr\u1ecb d\u00e0i ng\u00e0y.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>Th\u01b0\u1eddng g\u1eb7p: R\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a (bu\u1ed3n n\u00f4n, n\u00f4n, ti\u00eau ch\u1ea3y), ph\u1ea3n \u1ee9ng tr\u00ean da (ph\u00e1t ban, ng\u1ee9a).<\/li>\n<li>Nghi\u00eam tr\u1ecdng\/hi\u1ebfm g\u1eb7p: C\u00e1c ph\u1ea3n \u1ee9ng da \u0111e d\u1ecda t\u00ednh m\u1ea1ng (SJS, TEN), r\u1ed1i lo\u1ea1n huy\u1ebft h\u1ecdc (thi\u1ebfu m\u00e1u b\u1ea5t s\u1ea3n, m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t), ho\u1ea1i t\u1eed gan, suy th\u1eadn, t\u0103ng kali m\u00e1u, vi\u00eam m\u00e0ng n\u00e3o v\u00f4 khu\u1ea9n.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Bactrim\u00ae c\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi nhi\u1ec1u lo\u1ea1i thu\u1ed1c, c\u1ea7n th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 v\u1ec1 t\u1ea5t c\u1ea3 c\u00e1c lo\u1ea1i thu\u1ed1c \u0111ang s\u1eed d\u1ee5ng. C\u00e1c t\u01b0\u01a1ng t\u00e1c quan tr\u1ecdng c\u1ea7n l\u01b0u \u00fd:<\/p>\n<ul>\n<li>Warfarin: T\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u.<\/li>\n<li>Phenytoin: T\u0103ng nguy c\u01a1 \u0111\u1ed9c t\u00ednh c\u1ee7a phenytoin.<\/li>\n<li>Methotrexate: T\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a methotrexate, c\u00f3 th\u1ec3 g\u00e2y t\u1eed vong.<\/li>\n<li>Thu\u1ed1c g\u00e2y t\u0103ng kali m\u00e1u (thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n, l\u1ee3i ti\u1ec3u gi\u1eef kali): T\u0103ng nguy c\u01a1 t\u0103ng kali m\u00e1u nghi\u00eam tr\u1ecdng.<\/li>\n<li>Dofetilide: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng chung.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh. Thu\u1ed1c c\u00f3 th\u1ec3 qua nhau thai v\u00e0 s\u1eefa m\u1eb9, g\u00e2y nguy c\u01a1 v\u00e0ng da nh\u00e2n \u1edf tr\u1ebb s\u01a1 sinh.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ch\u00f3ng m\u1eb7t, l\u00fa l\u1eabn. C\u1ea7n th\u1eadn tr\u1ecdng khi th\u1ef1c hi\u1ec7n c\u00e1c c\u00f4ng vi\u1ec7c \u0111\u00f2i h\u1ecfi s\u1ef1 t\u1eadp trung.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>C\u00e1c tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 bao g\u1ed3m bu\u1ed3n n\u00f4n, n\u00f4n, ch\u00f3ng m\u1eb7t, l\u00fa l\u1eabn v\u00e0 \u1ee9c ch\u1ebf t\u1ee7y x\u01b0\u01a1ng. Khi nghi ng\u1edd qu\u00e1 li\u1ec1u, c\u1ea7n li\u00ean h\u1ec7 ngay v\u1edbi c\u01a1 s\u1edf y t\u1ebf g\u1ea7n nh\u1ea5t \u0111\u1ec3 \u0111\u01b0\u1ee3c x\u1eed tr\u00ed k\u1ecbp th\u1eddi.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Julia A Libecco, Keith R Powell. Trimethoprim\/sulfamethoxazole: clinical update, truy c\u1eadp ng\u00e0y 14 th\u00e1ng 07 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15520082\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/15520082\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Bactrim\u00ae 400\/80mg\/5ml \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty F. Hoffmann-La Roche., Ltd, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 3142\/QLD-KD, \u0111i\u1ec1u tr\u1ecb \u0111\u1ee3t c\u1ea5p vi\u00eam ph\u1ebf qu\u1ea3n m\u1ea1n t\u00ednh.<\/p>\n","protected":false},"author":1,"featured_media":126955,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-126952","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/126952","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=126952"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/126955"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=126952"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=126952"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=126952"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}