{"id":126893,"date":"2025-07-13T15:41:23","date_gmt":"2025-07-13T08:41:23","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=126893"},"modified":"2025-12-23T11:24:41","modified_gmt":"2025-12-23T04:24:41","slug":"bixebra-5mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/bixebra-5mg\/","title":{"rendered":"Bixebra 5mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Bixebra 5mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi KRKA, D.D., . Novo Mesto, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-22877-21.<\/strong><\/p>\n<h2>Bixebra 5mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean n\u00e9n bao phim <strong>Bixebra 5mg<\/strong> ch\u1ee9a 5mg <strong>Ivabradine<\/strong> (d\u01b0\u1edbi d\u1ea1ng Ivabradine hydrochloride).<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-22877-21<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u00f4\u0323p 4 vi\u0309 x 14 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Slovenia<\/p>\n<figure id=\"attachment_126898\" aria-describedby=\"caption-attachment-126898\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-126898\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Bixebra-5mg.jpg\" alt=\"Bixebra 5mg \u0111i\u1ec1u tr\u1ecb \u0111au th\u1eaft ng\u1ef1c \u1ed5n \u0111\u1ecbnh m\u1ea1n t\u00ednh\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Bixebra-5mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Bixebra-5mg-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Bixebra-5mg-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Bixebra-5mg-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-126898\" class=\"wp-caption-text\">Bixebra 5mg \u0111i\u1ec1u tr\u1ecb \u0111au th\u1eaft ng\u1ef1c \u1ed5n \u0111\u1ecbnh m\u1ea1n t\u00ednh<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Bixebra 5mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<ul>\n<li>Ivabradine ho\u1ea1t \u0111\u1ed9ng th\u00f4ng qua m\u1ed9t c\u01a1 ch\u1ebf \u0111\u1ed9c \u0111\u00e1o v\u00e0 chuy\u00ean bi\u1ec7t. N\u00f3 \u1ee9c ch\u1ebf m\u1ed9t c\u00e1ch ch\u1ecdn l\u1ecdc v\u00e0 \u0111\u1eb7c hi\u1ec7u k\u00eanh I<sub>f<\/sub> (&#8220;funny&#8221; current) t\u1ea1i n\u00fat xoang nh\u0129 (SA) c\u1ee7a tim. N\u00fat xoang l\u00e0 &#8220;m\u00e1y t\u1ea1o nh\u1ecbp&#8221; t\u1ef1 nhi\u00ean c\u1ee7a tim, v\u00e0 k\u00eanh I<sub>f<\/sub> \u0111\u00f3ng vai tr\u00f2 c\u1ed1t y\u1ebfu trong vi\u1ec7c ki\u1ec3m so\u00e1t t\u1ed1c \u0111\u1ed9 kh\u1eed c\u1ef1c t\u00e2m tr\u01b0\u01a1ng t\u1ef1 ph\u00e1t, qua \u0111\u00f3 quy\u1ebft \u0111\u1ecbnh t\u1ea7n s\u1ed1 nh\u1ecbp tim.<\/li>\n<li>B\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf k\u00eanh n\u00e0y, Ivabradine l\u00e0m gi\u1ea3m \u0111\u1ed9 d\u1ed1c c\u1ee7a qu\u00e1 tr\u00ecnh kh\u1eed c\u1ef1c t\u00e2m tr\u01b0\u01a1ng, d\u1eabn \u0111\u1ebfn l\u00e0m ch\u1eadm nh\u1ecbp tim khi ngh\u1ec9 ng\u01a1i v\u00e0 c\u1ea3 khi g\u1eafng s\u1ee9c. \u0110i\u1ec1u quan tr\u1ecdng l\u00e0 t\u00e1c d\u1ee5ng n\u00e0y c\u00f3 t\u00ednh \u0111\u1eb7c hi\u1ec7u cao:\n<ul>\n<li>Kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ee9c co b\u00f3p c\u01a1 tim (inotropism).<\/li>\n<li>Kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn th\u1eddi gian d\u1eabn truy\u1ec1n t\u00edn hi\u1ec7u trong c\u00e1c bu\u1ed3ng tim kh\u00e1c (d\u1eabn truy\u1ec1n nh\u0129-th\u1ea5t, n\u1ed9i th\u1ea5t).<\/li>\n<li>Kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn huy\u1ebft \u00e1p ho\u1eb7c t\u00e1i c\u1ef1c t\u00e2m th\u1ea5t.<\/li>\n<\/ul>\n<\/li>\n<li>Vi\u1ec7c gi\u1ea3m nh\u1ecbp tim gi\u00fap k\u00e9o d\u00e0i th\u1eddi gian t\u00e2m tr\u01b0\u01a1ng, c\u1ea3i thi\u1ec7n t\u01b0\u1edbi m\u00e1u v\u00e0 cung c\u1ea5p oxy cho c\u01a1 tim, t\u1eeb \u0111\u00f3 l\u00e0m gi\u1ea3m c\u00e1c c\u01a1n \u0111au th\u1eaft ng\u1ef1c. Trong suy tim, vi\u1ec7c gi\u1ea3m nh\u1ecbp tim \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 gi\u00fap gi\u1ea3m t\u1ef7 l\u1ec7 nh\u1eadp vi\u1ec7n v\u00e0 c\u1ea3i thi\u1ec7n ti\u00ean l\u01b0\u1ee3ng.<\/li>\n<\/ul>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Ivabradine \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh sau khi u\u1ed1ng v\u00e0 chuy\u1ec3n h\u00f3a m\u1ea1nh m\u1ebd t\u1ea1i gan v\u00e0 ru\u1ed9t th\u00f4ng qua enzyme cytochrom P450 3A4 (CYP3A4). Sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i c\u1ee7a thu\u1ed1c ch\u1ec9 kho\u1ea3ng 40% do hi\u1ec7u \u1ee9ng chuy\u1ec3n h\u00f3a l\u1ea7n \u0111\u1ea7u m\u1ea1nh. Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng c\u00f9ng b\u1eefa \u0103n \u0111\u1ec3 t\u0103ng h\u1ea5p thu v\u00e0 gi\u1ea3m s\u1ef1 bi\u1ebfn thi\u00ean gi\u1eefa c\u00e1c c\u00e1 th\u1ec3.<\/p>\n<h2>Thu\u1ed1c Bixebra 5mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng \u0111au th\u1eaft ng\u1ef1c \u1ed5n \u0111\u1ecbnh m\u1ea1n t\u00ednh: \u1ede ng\u01b0\u1eddi l\u1edbn b\u1ecb b\u1ec7nh \u0111\u1ed9ng m\u1ea1ch v\u00e0nh c\u00f3 nh\u1ecbp xoang b\u00ecnh th\u01b0\u1eddng v\u00e0 t\u1ea7n s\u1ed1 tim \u226570 nh\u1ecbp\/ph\u00fat.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb suy tim m\u1ea1n t\u00ednh: \u1ede nh\u1eefng b\u1ec7nh nh\u00e2n suy tim m\u1ea1n t\u00ednh (ph\u00e2n lo\u1ea1i NYHA II-IV) c\u00f3 r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng t\u00e2m thu, nh\u1ecbp xoang v\u00e0 t\u1ea7n s\u1ed1 tim \u226575 nh\u1ecbp\/ph\u00fat. Th\u01b0\u1eddng \u0111\u01b0\u1ee3c ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb chu\u1ea9n bao g\u1ed3m thu\u1ed1c ch\u1eb9n beta, ho\u1eb7c khi b\u1ec7nh nh\u00e2n c\u00f3 ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh\/kh\u00f4ng dung n\u1ea1p v\u1edbi thu\u1ed1c ch\u1eb9n beta.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Bixebra 5mg<\/h2>\n<p>Li\u1ec1u d\u00f9ng ph\u1ea3i \u0111\u01b0\u1ee3c c\u00e1 th\u1ec3 h\u00f3a v\u00e0 \u0111i\u1ec1u ch\u1ec9nh b\u1edfi b\u00e1c s\u0129. Li\u1ec1u kh\u1edfi \u0111\u1ea7u th\u00f4ng th\u01b0\u1eddng l\u00e0 5mg, 2 l\u1ea7n\/ng\u00e0y. Sau 3-4 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb, li\u1ec1u c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh (t\u0103ng l\u00ean 7.5mg x 2 l\u1ea7n\/ng\u00e0y ho\u1eb7c gi\u1ea3m xu\u1ed1ng 2.5mg x 2 l\u1ea7n\/ng\u00e0y) t\u00f9y theo \u0111\u00e1p \u1ee9ng c\u1ee7a b\u1ec7nh nh\u00e2n v\u00e0 t\u1ea7n s\u1ed1 tim m\u1ee5c ti\u00eau.<\/p>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Bixebra 5mg<\/h2>\n<ul>\n<li>Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng, 2 l\u1ea7n m\u1ed7i ng\u00e0y (m\u1ed9t vi\u00ean bu\u1ed5i s\u00e1ng v\u00e0 m\u1ed9t vi\u00ean bu\u1ed5i t\u1ed1i).<\/li>\n<li>N\u00ean u\u1ed1ng thu\u1ed1c trong b\u1eefa \u0103n \u0111\u1ec3 t\u0103ng hi\u1ec7u qu\u1ea3 h\u1ea5p thu.<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Bixebra 5mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>B\u1ea5t k\u1ef3 ai c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng hay qu\u00e1 m\u1eabn v\u1edbi ho\u1ea1t ch\u1ea5t Ivabradine ho\u1eb7c c\u00e1c th\u00e0nh ph\u1ea7n kh\u00e1c c\u00f3 trong thu\u1ed1c.<\/li>\n<li>Khi t\u1ea7n s\u1ed1 tim c\u1ee7a b\u1ec7nh nh\u00e2n l\u00fac ngh\u1ec9 ng\u01a1i th\u1ea5p h\u01a1n 70 nh\u1ecbp m\u1ed7i ph\u00fat tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb.<\/li>\n<li>B\u1ec7nh nh\u00e2n \u0111ang trong t\u00ecnh tr\u1ea1ng s\u1ed1c tim ho\u1eb7c v\u1eeba tr\u1ea3i qua m\u1ed9t c\u01a1n nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p.<\/li>\n<li>Nh\u1eefng tr\u01b0\u1eddng h\u1ee3p c\u00f3 huy\u1ebft \u00e1p \u1edf m\u1ee9c r\u1ea5t th\u1ea5p (\u0111\u01b0\u1ee3c \u0111\u1ecbnh ngh\u0129a l\u00e0 d\u01b0\u1edbi 90\/50 mmHg).<\/li>\n<li>Ng\u01b0\u1eddi b\u1ecb suy ch\u1ee9c n\u0103ng gan \u1edf m\u1ee9c \u0111\u1ed9 n\u1eb7ng.<\/li>\n<li>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh cho ng\u01b0\u1eddi m\u1eafc c\u00e1c r\u1ed1i lo\u1ea1n d\u1eabn truy\u1ec1n tim nghi\u00eam tr\u1ecdng nh\u01b0 h\u1ed9i ch\u1ee9ng suy n\u00fat xoang, block xoang nh\u0129, ho\u1eb7c block nh\u0129-th\u1ea5t ho\u00e0n to\u00e0n (\u0111\u1ed9 3).<\/li>\n<li>Vi\u1ec7c s\u1eed d\u1ee5ng thu\u1ed1c b\u1ecb c\u1ea5m \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u00e0 nh\u1ecbp tim c\u1ee7a h\u1ecd ph\u1ee5 thu\u1ed9c ho\u00e0n to\u00e0n v\u00e0o ho\u1ea1t \u0111\u1ed9ng c\u1ee7a m\u00e1y t\u1ea1o nh\u1ecbp.<\/li>\n<li>Nh\u1eefng b\u1ec7nh nh\u00e2n \u0111ang tr\u1ea3i qua c\u01a1n \u0111au th\u1eaft ng\u1ef1c \u1edf d\u1ea1ng kh\u00f4ng \u1ed5n \u0111\u1ecbnh.<\/li>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai, ph\u1ee5 n\u1eef cho con b\u00fa v\u00e0 ph\u1ee5 n\u1eef trong \u0111\u1ed9 tu\u1ed5i sinh \u0111\u1ebb kh\u00f4ng s\u1eed d\u1ee5ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai ph\u00f9 h\u1ee3p.<\/li>\n<li>D\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf m\u1ea1nh CYP3A4 (v\u00ed d\u1ee5: thu\u1ed1c kh\u00e1ng n\u1ea5m nh\u00f3m azol, kh\u00e1ng sinh macrolid, thu\u1ed1c \u1ee9c ch\u1ebf protease c\u1ee7a HIV).<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Bixebra 5mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Kh\u00f4ng n\u00ean b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb n\u1ebfu nh\u1ecbp tim khi ngh\u1ec9 &lt; 70 nh\u1ecbp\/ph\u00fat. N\u1ebfu trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, nh\u1ecbp tim th\u01b0\u1eddng xuy\u00ean &lt; 50 nh\u1ecbp\/ph\u00fat ho\u1eb7c b\u1ec7nh nh\u00e2n c\u00f3 c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a nh\u1ecbp tim ch\u1eadm (ch\u00f3ng m\u1eb7t, m\u1ec7t m\u1ecfi), c\u1ea7n ph\u1ea3i gi\u1ea3m li\u1ec1u ho\u1eb7c ng\u01b0ng thu\u1ed1c.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>R\u1ea5t ph\u1ed5 bi\u1ebfn: Hi\u1ec7n t\u01b0\u1ee3ng ch\u00f3i s\u00e1ng \u1edf m\u1eaft (phosphenes). \u0110\u00e2y l\u00e0 t\u00e1c d\u1ee5ng ph\u1ee5 \u0111\u1eb7c tr\u01b0ng nh\u1ea5t, \u0111\u01b0\u1ee3c m\u00f4 t\u1ea3 l\u00e0 c\u1ea3m gi\u00e1c t\u0103ng c\u01b0\u1eddng \u0111\u1ed9 s\u00e1ng tho\u00e1ng qua trong m\u1ed9t v\u00f9ng th\u1ecb tr\u01b0\u1eddng. Hi\u1ec7n t\u01b0\u1ee3ng n\u00e0y th\u01b0\u1eddng t\u1ef1 h\u1ebft v\u00e0 kh\u00f4ng nghi\u00eam tr\u1ecdng.<\/li>\n<li>Ph\u1ed5 bi\u1ebfn: Nh\u1ecbp tim ch\u1eadm, nh\u1ee9c \u0111\u1ea7u (th\u01b0\u1eddng trong th\u00e1ng \u0111\u1ea7u), ch\u00f3ng m\u1eb7t, nh\u00ecn m\u1edd.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh ph\u1ed1i h\u1ee3p: V\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf m\u1ea1nh CYP3A4 nh\u01b0 ketoconazole, itraconazole, clarithromycin, ritonavir&#8230; v\u00ec ch\u00fang l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Ivabradine l\u00ean nhi\u1ec1u l\u1ea7n.<\/p>\n<p>Th\u1eadn tr\u1ecdng khi ph\u1ed1i h\u1ee3p:<\/p>\n<ul>\n<li>C\u00e1c thu\u1ed1c l\u00e0m ch\u1eadm nh\u1ecbp tim kh\u00e1c (nh\u01b0 thu\u1ed1c ch\u1eb9n beta, diltiazem, verapamil) c\u00f3 th\u1ec3 l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng h\u1ea1 nh\u1ecbp tim.<\/li>\n<li>C\u00e1c thu\u1ed1c k\u00e9o d\u00e0i kho\u1ea3ng QT.<\/li>\n<li>N\u01b0\u1edbc \u00e9p b\u01b0\u1edfi ch\u00f9m c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Ivabradine v\u00e0 n\u00ean tr\u00e1nh s\u1eed d\u1ee5ng.<\/li>\n<li>C\u00e1c thu\u1ed1c c\u1ea3m \u1ee9ng CYP3A4 (nh\u01b0 rifampicin, barbiturat, St. John&#8217;s Wort) c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a Ivabradine.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Bixebra ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa do c\u00e1c d\u1eef li\u1ec7u tr\u00ean \u0111\u1ed9ng v\u1eadt cho th\u1ea5y \u0111\u1ed9c t\u00ednh tr\u00ean sinh s\u1ea3n.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>B\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c c\u1ea3nh b\u00e1o v\u1ec1 kh\u1ea3 n\u0103ng x\u1ea3y ra c\u00e1c hi\u1ec7n t\u01b0\u1ee3ng th\u1ecb gi\u00e1c tho\u00e1ng qua (phosphenes), \u0111\u1eb7c bi\u1ec7t khi l\u00e1i xe v\u00e0o ban \u0111\u00eam ho\u1eb7c trong \u0111i\u1ec1u ki\u1ec7n \u00e1nh s\u00e1ng thay \u0111\u1ed5i \u0111\u1ed9t ng\u1ed9t.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 g\u00e2y ra nh\u1ecbp tim ch\u1eadm nghi\u00eam tr\u1ecdng v\u00e0 k\u00e9o d\u00e0i. Vi\u1ec7c x\u1eed tr\u00ed c\u1ea7n \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n t\u1ea1i c\u01a1 s\u1edf y t\u1ebf, bao g\u1ed3m c\u00e1c bi\u1ec7n ph\u00e1p h\u1ed7 tr\u1ee3 tu\u1ea7n ho\u00e0n, theo d\u00f5i ch\u1eb7t ch\u1ebd v\u00e0 c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng thu\u1ed1c k\u00edch th\u00edch beta ho\u1eb7c \u0111\u1eb7t m\u00e1y t\u1ea1o nh\u1ecbp t\u1ea1m th\u1eddi n\u1ebfu c\u1ea7n thi\u1ebft.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea1n n\u00ean b\u1ea3o qu\u1ea3n thu\u1ed1c Bixebra 5mg\u00a0trong m\u00f4i tr\u01b0\u1eddng kh\u00f4 r\u00e1o, kh\u00f4ng c\u00f3 \u00e1nh s\u00e1ng tr\u1ef1c ti\u1ebfp chi\u1ebfu v\u00e0o. \u0110\u1ea3m b\u1ea3o nhi\u1ec7t \u0111\u1ed9 n\u01a1i c\u1ea5t gi\u1eef lu\u00f4n th\u1ea5p h\u01a1n <span class=\"math-inline\"><span class=\"katex\"><span class=\"katex-html\" aria-hidden=\"true\"><span class=\"base\"><span class=\"mord\">3<\/span><span class=\"mord\">0<span class=\"msupsub\"><span class=\"vlist-t\"><span class=\"vlist-r\"><span class=\"vlist\"><span class=\"\"><span class=\"sizing reset-size6 size3 mtight\"><span class=\"mbin mtight\">\u2218<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"mord text\"><span class=\"mord\">C<\/span><\/span><\/span><\/span><\/span><\/span>.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Bixebra 5mg<\/h2>\n<p><a href=\"https:\/\/vnras.com\/drug\/ivaprex-5-tablet\/\">Thu\u1ed1c Ivaprex 5 Tablet<\/a> ch\u1ee9a Ivabradine 5 mg, s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH D\u01b0\u1ee3c ph\u1ea9m Incepta (Bangladesh), S\u0110K: VN-22953-21.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Lucia Dallapellegrina, Edoardo Sciatti, Enrico Vizzardi. Ivabradine and endothelium: an update, truy c\u1eadp ng\u00e0y 13 th\u00e1ng 07 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32611276\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32611276\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Bixebra 5mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi KRKA, D.D., . Novo Mesto, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-22877-21, \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng \u0111au th\u1eaft ng\u1ef1c \u1ed5n \u0111\u1ecbnh m\u1ea1n t\u00ednh.<\/p>\n","protected":false},"author":1,"featured_media":126897,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-126893","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/126893","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=126893"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/126897"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=126893"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=126893"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=126893"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}