{"id":126756,"date":"2025-07-11T17:00:47","date_gmt":"2025-07-11T10:00:47","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=126756"},"modified":"2025-12-23T10:35:35","modified_gmt":"2025-12-23T03:35:35","slug":"cadisapc-80-25","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/cadisapc-80-25\/","title":{"rendered":"CadisAPC 80\/25"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>CadisAPC 80\/25 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty CPDP Ampharco U.S.A, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110382424 (VD-31587-19).<\/strong><\/p>\n<h2>CadisAPC 80\/25 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean n\u00e9n <strong>CadisAPC 80\/25<\/strong> ch\u1ee9a:<\/p>\n<ul>\n<li><strong>Telmisartan<\/strong>: 80 mg<\/li>\n<li>Chlorthalidone: 25 mg<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110382424 (VD-31587-19)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 v\u1ec9 x 10 vi\u00ean; H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean; H\u1ed9p 10 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_126759\" aria-describedby=\"caption-attachment-126759\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-126759\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/CadisAPC-8025.jpg\" alt=\"CadisAPC 80\/25\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/CadisAPC-8025.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/CadisAPC-8025-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/CadisAPC-8025-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/CadisAPC-8025-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-126759\" class=\"wp-caption-text\">CadisAPC 80\/25<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c CadisAPC 80\/25<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<ul>\n<li>Telmisartan: L\u00e0 m\u1ed9t thu\u1ed1c ch\u1eb9n th\u1ee5 th\u1ec3 Angiotensin II (ARB). Angiotensin II l\u00e0 m\u1ed9t ch\u1ea5t co m\u1ea1ch m\u1ea1nh trong c\u01a1 th\u1ec3. B\u1eb1ng c\u00e1ch ch\u1eb9n ch\u1ecdn l\u1ecdc th\u1ee5 th\u1ec3 AT1 m\u00e0 Angiotensin II g\u1eafn v\u00e0o, Telmisartan ng\u0103n ch\u1eb7n t\u00e1c d\u1ee5ng co m\u1ea1ch v\u00e0 gi\u1eef mu\u1ed1i-n\u01b0\u1edbc c\u1ee7a ch\u1ea5t n\u00e0y. K\u1ebft qu\u1ea3 l\u00e0 l\u00e0m gi\u00e3n m\u1ea1ch m\u00e1u, gi\u1ea3m s\u1ee9c c\u1ea3n ngo\u1ea1i bi\u00ean v\u00e0 h\u1ea1 huy\u1ebft \u00e1p.<\/li>\n<li>Chlorthalidone: L\u00e0 m\u1ed9t thu\u1ed1c l\u1ee3i ti\u1ec3u nh\u00f3m thiazide-like. N\u00f3 ho\u1ea1t \u0111\u1ed9ng ch\u1ee7 y\u1ebfu \u1edf \u1ed1ng l\u01b0\u1ee3n xa c\u1ee7a nephron, \u1ee9c ch\u1ebf t\u00e1i h\u1ea5p thu natri clorid (NaCl). \u0110i\u1ec1u n\u00e0y l\u00e0m t\u0103ng b\u00e0i ti\u1ebft natri v\u00e0 n\u01b0\u1edbc qua n\u01b0\u1edbc ti\u1ec3u, d\u1eabn \u0111\u1ebfn gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n v\u00e0 l\u00e0m h\u1ea1 huy\u1ebft \u00e1p.<\/li>\n<li>C\u01a1 ch\u1ebf hi\u1ec7p \u0111\u1ed3ng: S\u1ef1 k\u1ebft h\u1ee3p n\u00e0y mang l\u1ea1i hi\u1ec7u qu\u1ea3 c\u1ed9ng h\u1ee3p. Chlorthalidone l\u00e0m gi\u1ea3m th\u1ec3 t\u00edch m\u00e1u, c\u00f3 th\u1ec3 k\u00edch ho\u1ea1t h\u1ec7 Renin-Angiotensin-Aldosterone (RAAS). Telmisartan s\u1ebd \u0111\u1ed1i kh\u00e1ng l\u1ea1i s\u1ef1 k\u00edch ho\u1ea1t n\u00e0y. Ng\u01b0\u1ee3c l\u1ea1i, Telmisartan c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m nh\u1eb9 t\u00ecnh tr\u1ea1ng m\u1ea5t kali do Chlorthalidone g\u00e2y ra. S\u1ef1 ph\u1ed1i h\u1ee3p n\u00e0y gi\u00fap h\u1ea1 huy\u1ebft \u00e1p m\u1ea1nh m\u1ebd h\u01a1n so v\u1edbi vi\u1ec7c s\u1eed d\u1ee5ng ri\u00eang l\u1ebb t\u1eebng th\u00e0nh ph\u1ea7n v\u00e0 \u0111\u01b0\u1ee3c c\u00e1c hi\u1ec7p h\u1ed9i tim m\u1ea1ch uy t\u00edn khuy\u1ebfn ngh\u1ecb \u0111\u1ec3 s\u1edbm \u0111\u1ea1t huy\u1ebft \u00e1p m\u1ee5c ti\u00eau v\u00e0 t\u0103ng c\u01b0\u1eddng tu\u00e2n th\u1ee7 \u0111i\u1ec1u tr\u1ecb.<\/li>\n<\/ul>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>Telmisartan: H\u1ea5p thu nhanh qua \u0111\u01b0\u1eddng u\u1ed1ng, sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i kho\u1ea3ng 50%. N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 0.5-1.5 gi\u1edd. G\u1eafn k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (&gt;99.5%). Th\u1ea3i tr\u1eeb g\u1ea7n nh\u01b0 ho\u00e0n to\u00e0n qua ph\u00e2n.<\/li>\n<li>Chlorthalidone: H\u1ea5p thu t\u01b0\u01a1ng \u0111\u1ed1i t\u1ed1t sau khi u\u1ed1ng. N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh \u0111\u1ea1t \u0111\u01b0\u1ee3c sau kho\u1ea3ng 12 gi\u1edd. Th\u1eddi gian b\u00e1n th\u1ea3i d\u00e0i (kho\u1ea3ng 40-60 gi\u1edd), gi\u00fap duy tr\u00ec t\u00e1c d\u1ee5ng ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p \u1ed5n \u0111\u1ecbnh trong 24 gi\u1edd. Th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua th\u1eadn d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c CadisAPC 80\/25 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n.<\/li>\n<li>Vi\u1ec7c \u0111i\u1ec1u tr\u1ecb ph\u1ed1i h\u1ee3p n\u00e0y \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n ng\u01b0\u1eddi l\u1edbn kh\u00f4ng ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c ho\u00e0n to\u00e0n huy\u1ebft \u00e1p khi s\u1eed d\u1ee5ng Telmisartan ho\u1eb7c Chlorthalidone \u0111\u01a1n tr\u1ecb li\u1ec7u.<\/li>\n<li>C\u0169ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c xem x\u00e9t l\u00e0 li\u1ec7u ph\u00e1p kh\u1edfi \u0111\u1ea7u \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 tim m\u1ea1ch cao c\u1ea7n ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p t\u00edch c\u1ef1c.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c CadisAPC 80\/25<\/h2>\n<ul>\n<li>Li\u1ec1u d\u00f9ng: Li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 1 vi\u00ean\/l\u1ea7n\/ng\u00e0y.<\/li>\n<li>C\u00e1ch d\u00f9ng: C\u00f3 th\u1ec3 u\u1ed1ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng b\u1eefa \u0103n. N\u00ean u\u1ed1ng thu\u1ed1c v\u00e0o c\u00f9ng m\u1ed9t th\u1eddi \u0111i\u1ec3m m\u1ed7i ng\u00e0y \u0111\u1ec3 duy tr\u00ec n\u1ed3ng \u0111\u1ed9 thu\u1ed1c \u1ed5n \u0111\u1ecbnh trong m\u00e1u.<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c CadisAPC 80\/25 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Qu\u00e1 m\u1eabn v\u1edbi Telmisartan, Chlorthalidone, c\u00e1c d\u1eabn xu\u1ea5t sulfonamid kh\u00e1c, ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai 3 th\u00e1ng gi\u1eefa v\u00e0 3 th\u00e1ng cu\u1ed1i c\u1ee7a thai k\u1ef3.<\/li>\n<li>Ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa.<\/li>\n<li>B\u1ec7nh nh\u00e2n b\u1ecb t\u1eafc m\u1eadt ho\u1eb7c suy gan n\u1eb7ng.<\/li>\n<li>Suy th\u1eadn n\u1eb7ng (\u0111\u1ed9 thanh th\u1ea3i creatinin &lt; 30 ml\/ph\u00fat).<\/li>\n<li>V\u00f4 ni\u1ec7u.<\/li>\n<li>H\u1ea1 kali m\u00e1u, h\u1ea1 natri m\u00e1u, t\u0103ng calci m\u00e1u dai d\u1eb3ng.<\/li>\n<li>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c s\u1ea3n ph\u1ea9m ch\u1ee9a aliskiren \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng ho\u1eb7c suy th\u1eadn.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c CadisAPC 80\/25<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng cho b\u1ec7nh nh\u00e2n suy gan nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p c\u00f3 th\u1ec3 bao g\u1ed3m: ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, m\u1ec7t m\u1ecfi.<\/li>\n<li>\u00cdt g\u1eb7p h\u01a1n: h\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf \u0111\u1ee9ng, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a, y\u1ebfu c\u01a1, t\u0103ng acid uric m\u00e1u, t\u0103ng lipid m\u00e1u.<\/li>\n<li>Th\u00f4ng b\u00e1o ngay cho b\u00e1c s\u0129 ho\u1eb7c d\u01b0\u1ee3c s\u0129 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Lithium: D\u00f9ng \u0111\u1ed3ng th\u1eddi c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 v\u00e0 \u0111\u1ed9c t\u00ednh c\u1ee7a Lithium. Kh\u00f4ng khuy\u1ebfn c\u00e1o ph\u1ed1i h\u1ee3p.<\/li>\n<li>Thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00f4ng steroid (NSAIDs): C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng h\u1ea1 \u00e1p v\u00e0 t\u0103ng nguy c\u01a1 suy th\u1eadn.<\/li>\n<li>C\u00e1c thu\u1ed1c h\u1ea1 \u00e1p kh\u00e1c: C\u00f3 th\u1ec3 l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng h\u1ea1 \u00e1p, c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u.<\/li>\n<li>Thu\u1ed1c b\u1ed5 sung kali, l\u1ee3i ti\u1ec3u gi\u1eef kali: T\u0103ng nguy c\u01a1 t\u0103ng kali m\u00e1u.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ch\u00f3ng m\u1eb7t ho\u1eb7c bu\u1ed3n ng\u1ee7, do \u0111\u00f3 c\u1ea7n th\u1eadn tr\u1ecdng khi l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c cho \u0111\u1ebfn khi x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c \u0111\u00e1p \u1ee9ng c\u1ee7a c\u00e1 nh\u00e2n v\u1edbi thu\u1ed1c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<ul>\n<li>Tri\u1ec7u ch\u1ee9ng: Bi\u1ec3u hi\u1ec7n qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 l\u00e0 h\u1ea1 huy\u1ebft \u00e1p qu\u00e1 m\u1ee9c, nh\u1ecbp tim nhanh, r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i.<\/li>\n<li>X\u1eed tr\u00ed: \u0110i\u1ec1u tr\u1ecb ch\u1ee7 y\u1ebfu l\u00e0 h\u1ed7 tr\u1ee3 v\u00e0 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng, bao g\u1ed3m theo d\u00f5i ch\u1eb7t ch\u1ebd c\u00e1c d\u1ea5u hi\u1ec7u sinh t\u1ed3n v\u00e0 \u0111i\u1ec7n gi\u1ea3i \u0111\u1ed3.<\/li>\n<\/ul>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c CadisAPC 80\/25<\/h2>\n<p><a href=\"https:\/\/vnras.com\/drug\/telsol-plus-80mg-25mg\/\">Thu\u1ed1c Telsol Plus 80mg\/25mg<\/a> ch\u1ee9a th\u00e0nh ph\u1ea7n Telmisartan 80mg, Hydrochlorothiazide 25mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Laboratorios Liconsa, S.A c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-23033-22, l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Marco Lorena, Aldo Autolitano, Giovanni Natale, Federica Uberti, Fabrizio Vitali, Camillo Schiantarelli, Nicola Lucio Liberato. Telmisartan\/hydrochlorothiazide-induced hepatotoxicity, truy c\u1eadp ng\u00e0y 11 th\u00e1ng 07 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26322103\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/26322103\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c CadisAPC 80\/25 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty CPDP Ampharco U.S.A, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110382424 (VD-31587-19), ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n.<\/p>\n","protected":false},"author":1,"featured_media":126757,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-126756","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/126756","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=126756"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/126757"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=126756"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=126756"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=126756"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}