{"id":126606,"date":"2025-07-10T15:38:55","date_gmt":"2025-07-10T08:38:55","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=126606"},"modified":"2025-07-24T11:46:27","modified_gmt":"2025-07-24T04:46:27","slug":"clomedin-25mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/clomedin-25mg\/","title":{"rendered":"Clomedin 25mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, <a href=\"https:\/\/vnras.com\/drug\/\">d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Clomedin 25mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi REMEDICA LTD. (CH S\u00edp) c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN-22889-21<\/strong><\/p>\n<h2>Clomedin 25mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ng Clomedin 25mg<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<p>Ho\u1ea1t ch\u1ea5t: Clozapine 25mg<\/p>\n<p>T\u00e1 d\u01b0\u1ee3c: lactose, povidone, cellulose vi tinh th\u1ec3, tinh b\u1ed9t b\u1eafp, natri starch glycolate, magnesium stearate, talc.<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN-22889-21<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 5 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Cyprus<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Clomedin 25mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Clozapine ho\u1ea1t \u0111\u1ed9ng kh\u00e1c v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng lo\u1ea1n th\u1ea7n c\u1ed5 \u0111i\u1ec3n, nh\u1eafm m\u1ea1nh \u0111\u1ebfn th\u1ee5 th\u1ec3 dopamine D4 v\u00e0 \u00edt t\u00e1c \u0111\u1ed9ng \u1edf c\u00e1c th\u1ee5 th\u1ec3 D1, D2, D3, D5, t\u1eeb \u0111\u00f3 gi\u1ea3m nguy c\u01a1 t\u00e1c d\u1ee5ng ngo\u1ea1i th\u00e1p. Ngo\u00e0i ra c\u00f2n kh\u00e1ng adrenergic \u03b1, kh\u00e1ng cholinergic, c\u00f3 t\u00e1c d\u1ee5ng an th\u1ea7n v\u00e0 ch\u1ed1ng d\u1ecb \u1ee9ng.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu: Clozapine h\u1ea5p thu t\u1ed1t qua \u0111\u01b0\u1eddng u\u1ed1ng v\u1edbi sinh kh\u1ea3 d\u1ee5ng dao \u0111\u1ed9ng t\u1eeb 50\u201360%. D\u00f9ng th\u1ee9c \u0103n v\u1edbi Clozapine s\u1ebd kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 h\u1ea5p thu<\/li>\n<li>Ph\u00e2n b\u1ed1: Kho\u1ea3ng 95% l\u01b0\u1ee3ng clozapine khi v\u00e0o c\u01a1 th\u1ec3 g\u1eafn v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng<\/li>\n<li>Chuy\u1ec3n h\u00f3a: Chuy\u1ec3n ho\u00e1 Clozapine ch\u1ee7 y\u1ebfu t\u1ea1i gan nh\u1edd ph\u1ea7n l\u1edbn b\u1edfi 2 enzym CYP1A2, CYP3A4 v\u00e0 \u1edf m\u1ee9c \u0111\u1ed9 \u00edt h\u01a1n qua CYP2D6 v\u00e0 CYP2C19. M\u1ed9t ch\u1ea5t chuy\u1ec3n ho\u00e1 ho\u1ea1t \u0111\u1ed9ng sinh ra trong qu\u00e1 tr\u00ecnh n\u00e0y l\u00e0 demethyl nh\u01b0ng so v\u1edbi t\u00e1c d\u1ee5ng c\u1ee7a Clozapine th\u00ec ch\u1ea5t n\u00e0y y\u1ebfu h\u01a1n v\u00e0 th\u1ec3 hi\u1ec7n t\u00e1c d\u1ee5ng trong qu\u00e3ng th\u1eddi gian ng\u1eafnh \u01a1n<\/li>\n<li>Th\u1ea3i tr\u1eeb: Clozapine th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u (50%) v\u00e0 ph\u00e2n (30%), Trong \u0111\u00f3, th\u1eddi gian b\u00e1n h\u1ee7y trung b\u00ecnh l\u00e0 v\u00e0o kho\u1ea3ng 12 gi\u1edd.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Clomedin 25mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<ul>\n<li>T\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t kh\u00e1ng tr\u1ecb (\u0111\u00e3 \u0111i\u1ec1u tr\u1ecb b\u1eb1ng c\u00e1c thu\u1ed1c ch\u1ed1ng lo\u1ea1n th\u1ea7n kh\u00e1c m\u00e0 kh\u00f4ng hi\u1ec7u qu\u1ea3 ho\u1eb7c c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng)<\/li>\n<li>R\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n li\u00ean quan \u0111\u1ebfn b\u1ec7nh Parkinson khi c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb chu\u1ea9n kh\u00e1c kh\u00f4ng th\u1ec3 ki\u1ec3m so\u00e1t tri\u1ec7u ch\u1ee9ng<\/li>\n<\/ul>\n<figure id=\"attachment_126612\" aria-describedby=\"caption-attachment-126612\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-126612\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Clomedin-25mg-1.jpg\" alt=\"Clomedin 25mg\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Clomedin-25mg-1.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Clomedin-25mg-1-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Clomedin-25mg-1-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/Clomedin-25mg-1-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-126612\" class=\"wp-caption-text\">Thu\u1ed1c Clomedin 25mg ch\u1ee9a ho\u1ea1t ch\u1ea5t Clozapine &#8211; m\u1ed9t d\u1eabn xu\u1ea5t dibenzodiazepine, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb t\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t kh\u00e1ng tr\u1ecb v\u00e0 r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n do Parkinson.<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p><span style=\"text-decoration: underline;\">Kh\u1edfi \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb:<\/span><\/p>\n<ul>\n<li>B\u1eaft \u0111\u1ea7u v\u1edbi 12,5 mg Clozapin\/l\u1ea7n\/ng\u00e0y, c\u00f3 th\u1ec3 d\u00f9ng 1\u20132 l\u1ea7n trong ng\u00e0y \u0111\u1ea7u ti\u00ean.<\/li>\n<li>Ng\u00e0y th\u1ee9 hai: t\u0103ng l\u00ean 1 vi\u00ean Clomedin 25\/l\u1ea7n ho\u1eb7c chia 2 l\u1ea7n n\u1ebfu dung n\u1ea1p t\u1ed1t.<\/li>\n<\/ul>\n<p><span style=\"text-decoration: underline;\">T\u0103ng li\u1ec1u:<\/span><\/p>\n<ul>\n<li>N\u1ebfu b\u1ec7nh nh\u00e2n dung n\u1ea1p t\u1ed1t, c\u00f3 th\u1ec3 t\u0103ng th\u00eam 1-2 vi\u00ean Clomedin 25\/ng\u00e0y, cho \u0111\u1ebfn khi \u0111\u1ea1t li\u1ec1u 300 mg\/ng\u00e0y trong v\u00f2ng 2\u20133 tu\u1ea7n.<\/li>\n<li>Sau \u0111\u00f3, n\u1ebfu c\u1ea7n thi\u1ebft, c\u00f3 th\u1ec3 t\u0103ng th\u00eam 2\u20134 vi\u00ean Clomedin 25 m\u1ed7i 3 ng\u00e0y ho\u1eb7c m\u1ed7i tu\u1ea7n, t\u00f9y theo m\u1ee9c \u0111\u1ed9 dung n\u1ea1p v\u00e0 \u0111\u00e1p \u1ee9ng c\u1ee7a b\u1ec7nh nh\u00e2n.<\/li>\n<li>Li\u1ec1u \u0111i\u1ec1u tr\u1ecb <span style=\"color: #555555; font-size: 14.4px;\">th\u01b0\u1eddng n\u1eb1m trong kho\u1ea3ng 200\u2013450 mg\/ng\u00e0y, chia 2\u20133 l\u1ea7n u\u1ed1ng. <\/span>C\u00f3 th\u1ec3 chia li\u1ec1u kh\u00f4ng \u0111\u1ec1u, v\u1edbi ph\u1ea7n l\u1edbn li\u1ec1u d\u00f9ng v\u00e0o bu\u1ed5i t\u1ed1i \u0111\u1ec3 gi\u1ea3m t\u00e1c d\u1ee5ng an th\u1ea7n v\u00e0o ban ng\u00e0y.<\/li>\n<\/ul>\n<p><span style=\"text-decoration: underline;\">Li\u1ec1u t\u1ed1i \u0111a:<\/span><\/p>\n<ul>\n<li>M\u1ed9t s\u1ed1 \u00edt b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 c\u1ea7n li\u1ec1u cao h\u01a1n \u0111\u1ec3 \u0111\u1ea1t hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb.<\/li>\n<li>Li\u1ec1u t\u1ed1i \u0111a kh\u00f4ng n\u00ean v\u01b0\u1ee3t qu\u00e1 900 mg\/ng\u00e0y.<\/li>\n<li>Li\u1ec1u tr\u00ean 450mg\/ng\u00e0y c\u1ea7n ch\u00fa \u00fd v\u00ec g\u1eb7p nhi\u1ec1u t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng<\/li>\n<\/ul>\n<p><span style=\"text-decoration: underline;\">Li\u1ec1u duy tr\u00ec:<\/span><\/p>\n<ul>\n<li>Sau khi \u0111\u1ea1t hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb t\u1ed1i \u01b0u, n\u00ean gi\u1ea3m li\u1ec1u t\u1eeb t\u1eeb \u0111\u1ebfn m\u1ee9c th\u1ea5p nh\u1ea5t c\u00f3 th\u1ec3 m\u00e0 v\u1eabn duy tr\u00ec \u0111\u00e1p \u1ee9ng.<\/li>\n<li>Li\u1ec1u \u2264200 mg\/ng\u00e0y c\u00f3 th\u1ec3 d\u00f9ng m\u1ed9t l\u1ea7n duy nh\u1ea5t v\u00e0o bu\u1ed5i t\u1ed1i.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb n\u00ean \u0111\u01b0\u1ee3c ti\u1ebfp t\u1ee5c trong t\u1ed1i thi\u1ec3u 6 th\u00e1ng.<\/li>\n<\/ul>\n<p><span style=\"text-decoration: underline;\">Khi ng\u01b0ng \u0111i\u1ec1u tr\u1ecb:<\/span><\/p>\n<ul>\n<li>N\u1ebfu ng\u1eebng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t, \u0111\u1eb7c bi\u1ec7t l\u00e0 do ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i, c\u1ea7n theo d\u00f5i s\u00e1t c\u00e1c d\u1ea5u hi\u1ec7u t\u00e1i ph\u00e1t lo\u1ea1n th\u1ea7n.<\/li>\n<li>Khi c\u00f3 k\u1ebf ho\u1ea1ch d\u1eebng thu\u1ed1c, n\u00ean gi\u1ea3m li\u1ec1u d\u1ea7n trong 1\u20132 tu\u1ea7n.<\/li>\n<li>N\u1ebfu ph\u1ea3i ng\u1eebng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t do gi\u1ea3m b\u1ea1ch c\u1ea7u h\u1ea1t ho\u1eb7c c\u00e1c ph\u1ea3n \u1ee9ng nghi\u00eam tr\u1ecdng kh\u00e1c, c\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd.<\/li>\n<\/ul>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>U\u1ed1ng nguy\u00ean <strong>vi\u00ean n\u00e9n Clomedin 25mg<\/strong>, kh\u00f4ng nhai, c\u00f3 th\u1ec3 u\u1ed1ng \u0111\u1ed3ng th\u1eddi v\u1edbi th\u1ee9c \u0103n ho\u1eb7c kh\u00f4ng<\/p>\n<p>Nguy\u00ean t\u1eafc chung khi s\u1eed d\u1ee5ng:<\/p>\n<ul>\n<li>C\u1ea7n th\u1eadn tr\u1ecdng khi chuy\u1ec3n t\u1eeb thu\u1ed1c ch\u1ed1ng lo\u1ea1n th\u1ea7n kh\u00e1c sang Clozapine, kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng ph\u1ed1i h\u1ee3p c\u00f9ng l\u00fac.<\/li>\n<li>N\u00ean ng\u1eebng thu\u1ed1c ch\u1ed1ng lo\u1ea1n th\u1ea7n tr\u01b0\u1edbc \u0111\u00f3 b\u1eb1ng c\u00e1ch gi\u1ea3m li\u1ec1u d\u1ea7n, sau \u0111\u00f3 m\u1edbi b\u1eaft \u0111\u1ea7u d\u00f9ng Clozapine.<\/li>\n<li>Trong m\u1ecdi tr\u01b0\u1eddng h\u1ee3p, vi\u1ec7c t\u0103ng li\u1ec1u ph\u1ea3i \u0111\u01b0\u1ee3c ti\u1ebfn h\u00e0nh t\u1eeb t\u1eeb, c\u00f3 theo d\u00f5i s\u00e1t.<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Clomedin 25mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>D\u1ecb \u1ee9ng v\u1edbi Clozapine c\u00f3 trong Clomedin 25mg<\/li>\n<li>Ti\u1ec1n s\u1eed m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t, gi\u1ea3m b\u1ea1ch c\u1ea7u ho\u1eb7c gi\u1ea3m b\u1ea1ch c\u1ea7u h\u1ea1t (ngo\u1ea1i tr\u1eeb do h\u00f3a tr\u1ecb tr\u01b0\u1edbc \u0111\u00f3).<\/li>\n<li>M\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t do clozapine trong l\u1ea7n \u0111i\u1ec1u tr\u1ecb tr\u01b0\u1edbc.<\/li>\n<li>\u0110ang \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c c\u00f3 nguy c\u01a1 cao g\u00e2y suy t\u1ee7y (\u0111\u1eb7c bi\u1ec7t l\u00e0 thu\u1ed1c ch\u1ed1ng lo\u1ea1n th\u1ea7n ch\u1eadm).<\/li>\n<li>Suy t\u1ee7y x\u01b0\u01a1ng, suy gi\u1ea3m ch\u1ee9c n\u0103ng t\u1ee7y x\u01b0\u01a1ng.<\/li>\n<li>\u0110\u1ed9ng kinh kh\u00f4ng ki\u1ec3m so\u00e1t.<\/li>\n<li>T\u00ecnh tr\u1ea1ng r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n c\u1ea5p do r\u01b0\u1ee3u ho\u1eb7c ng\u1ed9 \u0111\u1ed9c thu\u1ed1c.<\/li>\n<li>H\u00f4n m\u00ea, \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng n\u1eb7ng.<\/li>\n<li>X\u1eb9p tu\u1ea7n ho\u00e0n<\/li>\n<li>R\u1ed1i lo\u1ea1n tim ho\u1eb7c th\u1eadn n\u1eb7ng (nh\u01b0 vi\u00eam c\u01a1 tim).<\/li>\n<li>B\u1ec7nh gan ti\u1ebfn tri\u1ec3n, suy gan, vi\u00eam gan do thu\u1ed1c c\u00f3 bi\u1ec3u hi\u1ec7n v\u00e0ng da, bu\u1ed3n n\u00f4n, ch\u00e1n \u0103n.<\/li>\n<li>Ru\u1ed9t li\u1ec7t (li\u1ec7t ru\u1ed9t c\u01a1 n\u0103ng).<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Gi\u1ea3m b\u1ea1ch c\u1ea7u h\u1ea1t: B\u1eaft bu\u1ed9c theo d\u00f5i c\u00f4ng th\u1ee9c m\u00e1u \u0111\u1ecbnh k\u1ef3: h\u00e0ng tu\u1ea7n trong 18 tu\u1ea7n \u0111\u1ea7u, sau \u0111\u00f3 \u00edt nh\u1ea5t 1 l\u1ea7n\/th\u00e1ng. Ng\u1eebng thu\u1ed1c ngay n\u1ebfu b\u1ea1ch c\u1ea7u gi\u1ea3m xu\u1ed1ng &lt;3000\/mm\u00b3 ho\u1eb7c b\u1ea1ch c\u1ea7u trung t\u00ednh &lt;1500\/mm\u00b3.<\/li>\n<li>Nguy c\u01a1 co gi\u1eadt: Li\u1ec1u cao c\u00f3 th\u1ec3 g\u00e2y co gi\u1eadt, c\u1ea7n th\u1eadn tr\u1ecdng \u1edf b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed \u0111\u1ed9ng kinh.<\/li>\n<li>T\u0103ng \u0111\u01b0\u1eddng huy\u1ebft v\u00e0 r\u1ed1i lo\u1ea1n chuy\u1ec3n h\u00f3a: C\u1ea3nh gi\u00e1c v\u1edbi nguy c\u01a1 \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng m\u1edbi kh\u1edfi ph\u00e1t ho\u1eb7c x\u1ea5u \u0111i.<\/li>\n<li>Vi\u00eam c\u01a1 tim: C\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n trong 2 th\u00e1ng \u0111\u1ea7u d\u00f9ng thu\u1ed1c. Theo d\u00f5i tri\u1ec7u ch\u1ee9ng (\u0111au ng\u1ef1c, kh\u00f3 th\u1edf, nh\u1ecbp tim nhanh).<\/li>\n<li>T\u0103ng c\u00e2n, r\u1ed1i lo\u1ea1n lipid: Theo d\u00f5i th\u1ec3 tr\u1ea1ng v\u00e0 x\u00e9t nghi\u1ec7m \u0111\u1ecbnh k\u1ef3.<\/li>\n<li>Nguy c\u01a1 h\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf, ng\u1ea5t: \u0110\u1eb7c bi\u1ec7t \u1edf giai \u0111o\u1ea1n \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb, ng\u01b0\u1eddi cao tu\u1ed5i ho\u1eb7c d\u00f9ng thu\u1ed1c huy\u1ebft \u00e1p k\u00e8m theo.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>Bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t, nh\u1ecbp tim nhanh, t\u1ee5t huy\u1ebft \u00e1p, t\u0103ng ti\u1ebft n\u01b0\u1edbc b\u1ecdt, t\u00e1o b\u00f3n, kh\u00f4 mi\u1ec7ng<\/li>\n<li>Co gi\u1eadt, h\u1ed9i ch\u1ee9ng \u00e1c t\u00ednh an th\u1ea7n kinh (NMS)<\/li>\n<li>C\u00e2n n\u1eb7ng t\u0103ng, r\u1ed1i lo\u1ea1n \u0111\u01b0\u1eddng huy\u1ebft<\/li>\n<li>Gi\u1ea3m b\u1ea1ch c\u1ea7u h\u1ea1t, vi\u00eam ph\u1ed5i h\u00edt, vi\u00eam c\u01a1 tim, ho\u1ea1i t\u1eed gan<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Kh\u00f4ng ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng lo\u1ea1n th\u1ea7n t\u00e1c d\u1ee5ng k\u00e9o d\u00e0i do nguy c\u01a1 g\u00e2y \u1ee9c ch\u1ebf t\u1ee7y v\u00e0 kh\u00f4ng th\u1ec3 lo\u1ea1i b\u1ecf k\u1ecbp th\u1eddi khi x\u1ea3y ra gi\u1ea3m b\u1ea1ch c\u1ea7u.<\/li>\n<li>Tr\u00e1nh d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c g\u00e2y gi\u1ea3m b\u1ea1ch c\u1ea7u v\u00e0 thu\u1ed1c an th\u1ea7n kh\u00e1c \u0111\u1ec3 h\u1ea1n ch\u1ebf t\u0103ng \u0111\u1ed9c t\u00ednh.<\/li>\n<li>Kh\u00f4ng d\u00f9ng v\u1edbi r\u01b0\u1ee3u v\u00e0 c\u00e1c ch\u1ebf ph\u1ea9m ch\u1ee9a c\u1ed3n, v\u00ec l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng an th\u1ea7n, m\u1ea5t c\u1ea3nh gi\u00e1c, nguy hi\u1ec3m khi l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/li>\n<\/ul>\n<p>Th\u1eadn tr\u1ecdng khi ph\u1ed1i h\u1ee3p:<\/p>\n<ul>\n<li>Thu\u1ed1c h\u1ea1 huy\u1ebft \u00e1p v\u00e0 \u1ee9c ch\u1ebf men chuy\u1ec3n: nguy c\u01a1 t\u1ee5t huy\u1ebft \u00e1p t\u01b0 th\u1ebf.<\/li>\n<li>Thu\u1ed1c g\u00e2y \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng: nh\u01b0 d\u1eabn xu\u1ea5t morphin, barbiturat, kh\u00e1ng histamin H1, benzodiazepin, clonidin\u2026 c\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u1ee9c ch\u1ebf th\u1ea7n kinh, nguy hi\u1ec3m khi \u0111i\u1ec1u khi\u1ec3n m\u00e1y m\u00f3c.<\/li>\n<li>Benzodiazepin v\u00e0 thu\u1ed1c t\u00e2m th\u1ea7n kh\u00e1c: c\u00f3 th\u1ec3 g\u00e2y tr\u1ee5y tim m\u1ea1ch, ng\u1eebng h\u00f4 h\u1ea5p.<\/li>\n<li>Thu\u1ed1c kh\u00e1ng cholinergic v\u00e0 atropin ho\u1eb7c t\u01b0\u01a1ng t\u1ef1: t\u0103ng nguy c\u01a1 t\u00e1o b\u00f3n, b\u00ed ti\u1ec3u, kh\u00f4 mi\u1ec7ng.<\/li>\n<li>Warfarin v\u00e0 c\u00e1c thu\u1ed1c g\u1eafn m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng: l\u00e0m thay \u0111\u1ed5i n\u1ed3ng \u0111\u1ed9 Clozapine ho\u1eb7c thu\u1ed1c ph\u1ed1i h\u1ee3p.<\/li>\n<li>Cimetidin: l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Clozapine, t\u0103ng t\u00e1c d\u1ee5ng ph\u1ee5.<\/li>\n<li>Phenytoin v\u00e0 thu\u1ed1c c\u1ea3m \u1ee9ng CYP450: l\u00e0m gi\u1ea3m hi\u1ec7u l\u1ef1c Clozapine, g\u00e2y t\u00e1i ph\u00e1t tri\u1ec7u ch\u1ee9ng lo\u1ea1n th\u1ea7n.<\/li>\n<li>Lithium v\u00e0 thu\u1ed1c an th\u1ea7n kh\u00e1c: t\u0103ng nguy c\u01a1 h\u1ed9i ch\u1ee9ng \u00e1c t\u00ednh.<\/li>\n<li>Adrenaline v\u00e0 d\u1eabn xu\u1ea5t: c\u00f3 th\u1ec3 g\u00e2y t\u1ee5t huy\u1ebft \u00e1p ph\u1ea3n \u1ee9ng.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai: Do c\u00f2n h\u1ea1n ch\u1ebf c\u00e1c nghi\u00ean c\u1ee9u li\u00ean quan n\u1ec1n ch\u1ec9 d\u00f9ng Clomedin 25mg khi l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1, c\u1ea7n \u0111\u00e1nh gi\u00e1 k\u1ef9.<\/p>\n<p>Cho con b\u00fa: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh do Clozapine b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 v\u00e0 c\u00f3 th\u1ec3 g\u00e2y an th\u1ea7n, gi\u1ea3m tr\u01b0\u01a1ng l\u1ef1c c\u01a1 v\u00e0 co gi\u1eadt \u1edf tr\u1ebb b\u00fa m\u1eb9.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t, m\u1ea5t t\u1eadp trung c\u00f3 th\u1ec3 g\u1eb7p \u1edf b\u1ec7nh nh\u00e2n khi d\u00f9ng Clomedin, n\u00eanr\u00e1nh l\u00e1i xe\/v\u1eadn h\u00e0nh m\u00e1y trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tri\u1ec7u ch\u1ee9ng:L\u00fa l\u1eabn, co gi\u1eadt, tr\u1ee5y m\u1ea1ch, r\u1ed1i lo\u1ea1n nh\u1ecbp, suy h\u00f4 h\u1ea5p, h\u00f4n m\u00ea<\/p>\n<p>X\u1eed tr\u00ed:<\/p>\n<ul>\n<li>R\u1eeda d\u1ea1 d\u00e0y, d\u00f9ng than ho\u1ea1t n\u1ebfu b\u1ec7nh nh\u00e2n t\u1ec9nh v\u00e0 trong 6 gi\u1edd \u0111\u1ea7u<\/li>\n<li>Theo d\u00f5i s\u00e1t huy\u1ebft \u00e1p, nh\u1ecbp tim, ch\u1ee9c n\u0103ng h\u00f4 h\u1ea5p \u2013 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng t\u00edch c\u1ef1c<\/li>\n<li>Kh\u00f4ng d\u00f9ng adrenaline \u0111\u1ec3 x\u1eed tr\u00ed h\u1ea1 huy\u1ebft \u00e1p v\u00ec nguy c\u01a1 ph\u1ea3n \u1ee9ng nghi\u00eam tr\u1ecdng<\/li>\n<\/ul>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<ul>\n<li>Gi\u1eef Clomedin 25mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/li>\n<li>Kh\u00f4ng \u0111\u1ec3 Clomedin 25mg trong t\u1ea7m v\u1edbi tr\u1ebb em<\/li>\n<li>Kh\u00f4ng s\u1eed d\u1ee5ng Clomedin 25mg khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/li>\n<\/ul>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1<\/h2>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Clomedin 25mg nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/lepigin-25\/\">Lepigin 25<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Clozapin 25mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c Danapha, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb t\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/clozapyl-25\/\">Clozapyl-25<\/a> c\u00f3 th\u00e0nh ph\u1ea7n l\u00e0 Clozapin 25mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Torrent Pharma (\u1ea4n \u0110\u1ed9), \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb t\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Clomedin 25mg \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/To-huong-dan-su-dung-thuoc-clomedin-tablets-100mg-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 10 th\u00e1ng 7 n\u0103m 2025.<\/li>\n<li>Dragoi AM, Radulescu I, N\u0103sui BA, Pop AL, Varlas VN, Trifu S (2020). Clozapine: An Updated Overview of Pharmacogenetic Biomarkers, Risks, and Safety-Particularities in the Context of COVID-19. Brain Sci. Truy c\u1eadp ng\u00e0y 10 th\u00e1ng 7 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7697202\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7697202\/<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p><span style=\"font-weight: 400;\">Thu\u1ed1c Clomedin 25mg ch\u1ee9a ho\u1ea1t ch\u1ea5t Clozapine &#8211; m\u1ed9t d\u1eabn xu\u1ea5t dibenzodiazepine, \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb t\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t kh\u00e1ng tr\u1ecb v\u00e0 r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n do Parkinson. <\/span><\/p>\n","protected":false},"author":1,"featured_media":126611,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-126606","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/126606","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=126606"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/126611"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=126606"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=126606"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=126606"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}