{"id":125999,"date":"2025-07-04T16:57:20","date_gmt":"2025-07-04T09:57:20","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&p=125999"},"modified":"2025-12-23T10:24:32","modified_gmt":"2025-12-23T03:24:32","slug":"huether-25","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/huether-25\/","title":{"rendered":"Huether-25"},"content":{"rendered":"

Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> Huether-25 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa (Davipharm), c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110593524 (VD-28463-17).<\/strong><\/p>\n

Huether-25 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n
Th\u00e0nh ph\u1ea7n<\/h3>\n
M\u1ed7i vi\u00ean Huether-25<\/strong> ch\u1ee9a 25mg ho\u1ea1t ch\u1ea5t Topiramate<\/strong>. Topiramate l\u00e0 th\u00e0nh ph\u1ea7n d\u01b0\u1ee3c l\u00fd ch\u00ednh ch\u1ecbu tr\u00e1ch nhi\u1ec7m cho c\u00e1c t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u1ee7a thu\u1ed1c.<\/p>\n
Tr\u00ecnh b\u00e0y<\/h3>\n
S\u0110K: 893110593524 (VD-28463-17)<\/p>\n
Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 6 v\u1ec9 x 10 vi\u00ean<\/p>\n
Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n
$\"Huether-25$
Huether-25 \u0111i\u1ec1u tr\u1ecb \u0111\u1ed9ng kinh<\/figcaption><\/figure>\n
T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Huether-25<\/h2>\n
C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n
Topiramate t\u00e1c \u0111\u1ed9ng th\u00f4ng qua nhi\u1ec1u c\u01a1 ch\u1ebf kh\u00e1c nhau tr\u00ean h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng:<\/p>\n
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Ch\u1eb9n k\u00eanh natri ph\u1ee5 thu\u1ed9c \u0111i\u1ec7n th\u1ebf: \u1ee8c ch\u1ebf c\u00e1c k\u00eanh natri, gi\u00fap \u1ed5n \u0111\u1ecbnh m\u00e0ng t\u1ebf b\u00e0o th\u1ea7n kinh v\u00e0 ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t sinh \u0111i\u1ec7n th\u1ebf ho\u1ea1t \u0111\u1ed9ng l\u1eb7p l\u1ea1i nhanh ch\u00f3ng, gi\u1ea3m h\u01b0ng ph\u1ea5n qu\u00e1 m\u1ee9c c\u1ee7a t\u1ebf b\u00e0o th\u1ea7n kinh.<\/li>\n
T\u0103ng c\u01b0\u1eddng ho\u1ea1t \u0111\u1ed9ng GABA: T\u0103ng c\u01b0\u1eddng ho\u1ea1t \u0111\u1ed9ng c\u1ee7a GABA, m\u1ed9t ch\u1ea5t d\u1eabn truy\u1ec1n th\u1ea7n kinh \u1ee9c ch\u1ebf, th\u00f4ng qua vi\u1ec7c \u0111i\u1ec1u bi\u1ebfn c\u00e1c th\u1ee5 th\u1ec3 GABA-A, l\u00e0m t\u0103ng d\u00f2ng ion clorua v\u00e0o t\u1ebf b\u00e0o th\u1ea7n kinh.<\/li>\n
\u0110\u1ed1i kh\u00e1ng th\u1ee5 th\u1ec3 AMPA\/kainate c\u1ee7a glutamat: Ch\u1eb7n c\u00e1c th\u1ee5 th\u1ec3 AMPA v\u00e0 kainate, l\u00e0m gi\u1ea3m t\u00edn hi\u1ec7u k\u00edch th\u00edch trong n\u00e3o.<\/li>\n
\u1ee8c ch\u1ebf enzym carbonic anhydrase: \u1ee8c ch\u1ebf ch\u1ecdn l\u1ecdc c\u00e1c d\u1ea1ng enzym carbonic anhydrase, c\u00f3 th\u1ec3 g\u00f3p ph\u1ea7n v\u00e0o t\u00e1c d\u1ee5ng ch\u1ed1ng co gi\u1eadt.<\/li>\n
\u1ee8c ch\u1ebf k\u00eanh canxi lo\u1ea1i L: Gi\u1ea3m d\u00f2ng ion canxi v\u00e0o t\u1ebf b\u00e0o th\u1ea7n kinh, gi\u1ea3m t\u00ednh h\u01b0ng ph\u1ea5n.<\/li>\n<\/ul>\n
\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n
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H\u1ea5p thu: Topiramate \u0111\u01b0\u1ee3c h\u1ea5p thu t\u1ed1t t\u1eeb \u0111\u01b0\u1eddng ti\u00eau h\u00f3a (>80% sinh kh\u1ea3 d\u1ee5ng). N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c trong kho\u1ea3ng 2-3 gi\u1edd.<\/li>\n
Ph\u00e2n b\u1ed1: T\u1ef7 l\u1ec7 g\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng th\u1ea5p (15% \u0111\u1ebfn 41% ho\u1eb7c 9% \u0111\u1ebfn 17% ), gi\u1ea3m thi\u1ec3u nguy c\u01a1 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c do c\u1ea1nh tranh v\u1ecb tr\u00ed g\u1eafn k\u1ebft protein. Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 l\u00e0 0.6-0.8 L\/kg.<\/li>\n
Chuy\u1ec3n h\u00f3a: Kho\u1ea3ng 20% Topiramate \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a \u1edf gan, t\u1ef7 l\u1ec7 n\u00e0y c\u00f3 th\u1ec3 t\u0103ng l\u00ean \u0111\u1ebfn 50% khi c\u00f3 m\u1eb7t c\u00e1c thu\u1ed1c g\u00e2y c\u1ea3m \u1ee9ng enzym.<\/li>\n
Th\u1ea3i tr\u1eeb: Topiramate th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua th\u1eadn, c\u1ea3 d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i v\u00e0 d\u1ea1ng ch\u1ea5t chuy\u1ec3n h\u00f3a. Th\u1eddi gian b\u00e1n th\u1ea3i trung b\u00ecnh trong huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 21 gi\u1edd.<\/li>\n<\/ul>\n
Thu\u1ed1c Huether-25 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n
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\u0110i\u1ec1u tr\u1ecb \u0111\u1ed9ng kinh:\n
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\u0110\u01a1n tr\u1ecb li\u1ec7u ban \u0111\u1ea7u cho b\u1ec7nh nh\u00e2n t\u1eeb 2 tu\u1ed5i tr\u1edf l\u00ean c\u00f3 c\u00e1c c\u01a1n \u0111\u1ed9ng kinh kh\u1edfi ph\u00e1t c\u1ee5c b\u1ed9 ho\u1eb7c co c\u1ee9ng-co gi\u1eadt to\u00e0n th\u00e2n nguy\u00ean ph\u00e1t.<\/li>\n
Li\u1ec7u ph\u00e1p h\u1ed7 tr\u1ee3 cho ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 2 \u0111\u1ebfn 16 tu\u1ed5i c\u00f3 c\u00e1c c\u01a1n \u0111\u1ed9ng kinh kh\u1edfi ph\u00e1t c\u1ee5c b\u1ed9 ho\u1eb7c co c\u1ee9ng-co gi\u1eadt to\u00e0n th\u00e2n nguy\u00ean ph\u00e1t.<\/li>\n
Li\u1ec7u ph\u00e1p h\u1ed7 tr\u1ee3 cho b\u1ec7nh nh\u00e2n t\u1eeb 2 tu\u1ed5i tr\u1edf l\u00ean b\u1ecb c\u00e1c c\u01a1n \u0111\u1ed9ng kinh li\u00ean quan \u0111\u1ebfn h\u1ed9i ch\u1ee9ng Lennox-Gastaut.<\/li>\n<\/ul>\n<\/li>\n
D\u1ef1 ph\u00f2ng \u0111au n\u1eeda \u0111\u1ea7u: \u0110\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 d\u1ef1 ph\u00f2ng \u0111au n\u1eeda \u0111\u1ea7u \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 12 tu\u1ed5i tr\u1edf l\u00ean. C\u1ea7n l\u01b0u \u00fd thu\u1ed1c ch\u1ec9 c\u00f3 t\u00e1c d\u1ee5ng d\u1ef1 ph\u00f2ng ho\u1eb7c gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng c\u01a1n \u0111au n\u1eeda \u0111\u1ea7u, kh\u00f4ng \u0111i\u1ec1u tr\u1ecb c\u01a1n \u0111au \u0111\u1ea7u \u0111\u00e3 kh\u1edfi ph\u00e1t.<\/li>\n<\/ul>\n
Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Huether-25<\/h2>\n\n\n\n\n\n\n\n\n
Ch\u1ec9 \u0111\u1ecbnh<\/td>\n \u0110\u1ed1i t\u01b0\u1ee3ng<\/td>\n Li\u1ec1u kh\u1edfi \u0111\u1ea7u<\/td>\n T\u1ed1c \u0111\u1ed9 d\u00f2 li\u1ec1u<\/td>\n Li\u1ec1u m\u1ee5c ti\u00eau\/duy tr\u00ec<\/td>\n Li\u1ec1u t\u1ed1i \u0111a khuy\u1ebfn c\u00e1o<\/td>\n<\/tr>\n
\u0110\u01a1n tr\u1ecb li\u1ec7u \u0111\u1ed9ng kinh<\/td>\n Ng\u01b0\u1eddi l\u1edbn<\/td>\n 25 mg\/ng\u00e0y (u\u1ed1ng bu\u1ed5i t\u1ed1i) trong 1 tu\u1ea7n<\/td>\n T\u0103ng 25-50 mg\/ng\u00e0y m\u1ed7i 1-2 tu\u1ea7n, chia 2 l\u1ea7n<\/td>\n Kho\u1ea3ng 400 mg\/ng\u00e0y, chia 2 l\u1ea7n<\/td>\n 1.000 mg\/ng\u00e0y (m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n kh\u00e1ng thu\u1ed1c dung n\u1ea1p)<\/td>\n<\/tr>\n
\u0110i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 \u0111\u1ed9ng kinh<\/td>\n Tr\u1ebb em (\u2265 2 tu\u1ed5i)<\/td>\n 25 mg\/ng\u00e0y (u\u1ed1ng bu\u1ed5i t\u1ed1i) trong 1 tu\u1ea7n (ho\u1eb7c 1-3 mg\/kg\/ng\u00e0y)<\/td>\n T\u0103ng 1-3 mg\/kg\/ng\u00e0y m\u1ed7i 1-2 tu\u1ea7n, chia 2 l\u1ea7n<\/td>\n D\u00f2 li\u1ec1u trong 5-7 tu\u1ea7n \u0111\u1ec3 \u0111\u1ea1t li\u1ec1u duy tr\u00ec d\u1ef1a tr\u00ean c\u00e2n n\u1eb7ng<\/td>\n 30 mg\/kg\/ng\u00e0y (t\u1ed5ng li\u1ec1u kh\u00f4ng qu\u00e1 400 mg\/ng\u00e0y)<\/td>\n<\/tr>\n
Ng\u01b0\u1eddi l\u1edbn<\/td>\n 25-50 mg\/ng\u00e0y (u\u1ed1ng bu\u1ed5i t\u1ed1i) trong 1 tu\u1ea7n<\/td>\n T\u0103ng 25-50 mg\/ng\u00e0y m\u1ed7i 1-2 tu\u1ea7n, chia 2 l\u1ea7n<\/td>\n Kho\u1ea3ng 200-400 mg\/ng\u00e0y, chia 2 l\u1ea7n<\/td>\n 500 mg\/ng\u00e0y<\/td>\n<\/tr>\n
Tr\u1ebb em (\u2265 2 tu\u1ed5i)<\/td>\n 25 mg\/ng\u00e0y (u\u1ed1ng bu\u1ed5i t\u1ed1i) trong 1 tu\u1ea7n (ho\u1eb7c 1-3 mg\/kg\/ng\u00e0y)<\/td>\n T\u0103ng 1-3 mg\/kg\/ng\u00e0y m\u1ed7i 1-2 tu\u1ea7n, chia 2 l\u1ea7n<\/td>\n Kho\u1ea3ng 5-9 mg\/kg\/ng\u00e0y, chia 2 l\u1ea7n<\/td>\n T\u1ed5ng li\u1ec1u kh\u00f4ng qu\u00e1 400 mg\/ng\u00e0y<\/td>\n<\/tr>\n
D\u1ef1 ph\u00f2ng \u0111au n\u1eeda \u0111\u1ea7u<\/td>\n Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em (\u2265 12 tu\u1ed5i)<\/td>\n 25 mg\/ng\u00e0y (u\u1ed1ng bu\u1ed5i t\u1ed1i) trong 1 tu\u1ea7n<\/td>\n T\u0103ng 25 mg\/ng\u00e0y m\u1ed7i tu\u1ea7n<\/td>\n 100 mg\/ng\u00e0y, chia 2 l\u1ea7n<\/td>\n 200 mg\/ng\u00e0y (c\u1ea7n th\u1eadn tr\u1ecdng do t\u0103ng t\u00e1c d\u1ee5ng ph\u1ee5)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Huether-25<\/h2>\n
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\u0110\u01b0\u1eddng d\u00f9ng: Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng.<\/li>\n
Th\u1eddi \u0111i\u1ec3m d\u00f9ng thu\u1ed1c: C\u00f3 th\u1ec3 u\u1ed1ng m\u1ed9t l\u1ea7n ho\u1eb7c hai l\u1ea7n m\u1ed7i ng\u00e0y, th\u01b0\u1eddng khuy\u1ebfn c\u00e1o b\u1eaft \u0111\u1ea7u v\u00e0o bu\u1ed5i t\u1ed1i.<\/li>\n<\/ul>\n
Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Huether-25 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n
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Qu\u00e1 m\u1eabn: B\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn v\u1edbi Topiramate ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n
S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi Metformin: Do t\u0103ng nguy c\u01a1 toan chuy\u1ec3n h\u00f3a.<\/li>\n
S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf carbonic anhydrase kh\u00e1c: Tr\u00e1nh d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi acetazolamide, dorzolamide, brinzolamide do t\u0103ng nguy c\u01a1 toan chuy\u1ec3n h\u00f3a v\u00e0 s\u1ecfi th\u1eadn.<\/li>\n<\/ul>\n
L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Huether-25<\/h2>\n
Th\u1eadn tr\u1ecdng<\/h3>\n
Ng\u1eebng thu\u1ed1c ch\u1ed1ng \u0111\u1ed9ng kinh (AEDs): N\u00ean ng\u1eebng t\u1eeb t\u1eeb \u0111\u1ec3 tr\u00e1nh nguy c\u01a1 t\u0103ng c\u01a1n \u0111\u1ed9ng kinh t\u00e1i ph\u00e1t.<\/p>\n
T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n
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R\u1ea5t th\u01b0\u1eddng g\u1eb7p (>10%): D\u1ecb c\u1ea3m, ch\u00f3ng m\u1eb7t, bu\u1ed3n ng\u1ee7, ch\u00e1n \u0103n, gi\u1ea3m c\u00e2n, m\u1ec7t m\u1ecfi, ti\u00eau ch\u1ea3y, vi\u00eam m\u0169i h\u1ecdng, tr\u1ea7m c\u1ea3m.<\/li>\n
Th\u01b0\u1eddng g\u1eb7p (1% \u0111\u1ebfn 10%): Lo l\u1eafng, ch\u1eadm v\u1eadn \u0111\u1ed9ng t\u00e2m th\u1ea7n, kh\u00f3 kh\u0103n v\u1ec1 tr\u00ed nh\u1edb, kh\u00f3 t\u1eadp trung, r\u1ed1i lo\u1ea1n ng\u00f4n ng\u1eef, thay \u0111\u1ed5i v\u1ecb gi\u00e1c, bu\u1ed3n n\u00f4n, \u0111au b\u1ee5ng, s\u1ed1t, m\u1edd m\u1eaft, m\u1ea5t ng\u1ee7, y\u1ebfu c\u01a1, kh\u00f4 mi\u1ec7ng, t\u00e1o b\u00f3n, vi\u00eam ph\u1ebf qu\u1ea3n, \u0111au kh\u1edbp, ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn.<\/li>\n
\u00cdt g\u1eb7p (0.1% \u0111\u1ebfn 1%): K\u00edch \u0111\u1ed9ng, c\u00e1u k\u1ec9nh, \u0111au ng\u1ef1c, gi\u1ea3m c\u1ea3m gi\u00e1c, m\u1ea5t h\u1ee9ng th\u00fa, ch\u1ea3y m\u00e1u n\u01b0\u1edbu, \u0111au h\u1ecdng, ph\u00f9 m\u1ea1ch, s\u01b0ng kh\u1edbp, kh\u00f3 th\u1edf khi g\u1eafng s\u1ee9c.<\/li>\n
Hi\u1ebfm g\u1eb7p (<0.1%): M\u00e1u trong n\u01b0\u1edbc ti\u1ec3u, \u0111i ti\u1ec3u kh\u00f3\/\u0111au, m\u1ea5t th\u00ednh l\u1ef1c, ng\u1ee9a, ph\u00e1t ban da, m\u1ea5t ki\u1ec3m so\u00e1t b\u00e0ng quang, \u0111au l\u01b0ng d\u01b0\u1edbi, ch\u1ea3y m\u00e1u cam, da xanh xao, \u00f9 tai, s\u01b0ng, kh\u00f3 th\u1edf, kh\u00f3 ch\u1ecbu \u1edf chi.<\/li>\n<\/ul>\n
T\u01b0\u01a1ng t\u00e1c<\/h3>\n
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Thu\u1ed1c ng\u1eeba thai \u0111\u01b0\u1eddng u\u1ed1ng: C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a thu\u1ed1c, \u0111\u1eb7c bi\u1ec7t \u1edf li\u1ec1u tr\u00ean 200 mg\/ng\u00e0y.<\/li>\n
C\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u1ed9ng kinh kh\u00e1c (AEDs):\n
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Acid Valproic: C\u00f3 th\u1ec3 g\u00e2y h\u1ea1 th\u00e2n nhi\u1ec7t, m\u1ec7t m\u1ecfi, l\u00fa l\u1eabn, t\u0103ng n\u1ed3ng \u0111\u1ed9 amoniac trong m\u00e1u.<\/li>\n
Carbamazepine: C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 Topiramate trong huy\u1ebft t\u01b0\u01a1ng.<\/li>\n
Zonisamide: T\u0103ng nguy c\u01a1 v\u00e0 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a toan chuy\u1ec3n h\u00f3a.<\/li>\n<\/ul>\n<\/li>\n
Thu\u1ed1c \u1ee9c ch\u1ebf carbonic anhydrase kh\u00e1c: Tr\u00e1nh d\u00f9ng \u0111\u1ed3ng th\u1eddi do t\u0103ng nguy c\u01a1 toan chuy\u1ec3n h\u00f3a v\u00e0 s\u1ecfi th\u1eadn.<\/li>\n
Thu\u1ed1c \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng: C\u00f3 th\u1ec3 g\u00e2y an th\u1ea7n v\u00e0 \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng qu\u00e1 m\u1ee9c.<\/li>\n
Metformin: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi do t\u0103ng nguy c\u01a1 toan chuy\u1ec3n h\u00f3a.<\/li>\n
Lithium: N\u1ed3ng \u0111\u1ed9 lithium c\u00f3 th\u1ec3 t\u0103ng khi d\u00f9ng Topiramate li\u1ec1u cao (600 mg\/ng\u00e0y).<\/li>\n
Amitriptyline: \u0110\u1ed9 thanh th\u1ea3i c\u1ee7a Topiramate c\u00f3 th\u1ec3 gi\u1ea3m.<\/li>\n
T\u01b0\u01a1ng t\u00e1c v\u1edbi th\u1ef1c ph\u1ea9m\/\u0111\u1ed3 u\u1ed1ng: R\u01b0\u1ee3u (Ethanol): Kh\u00f4ng n\u00ean u\u1ed1ng r\u01b0\u1ee3u khi \u0111ang d\u00f9ng Topiramate v\u00ec c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n ng\u1ee7 qu\u00e1 m\u1ee9c, l\u00fa l\u1eabn, kh\u00f3 kh\u0103n v\u1ec1 tr\u00ed nh\u1edb ho\u1eb7c l\u1eddi n\u00f3i, v\u00e0 t\u0103ng nguy c\u01a1 co gi\u1eadt.<\/li>\n<\/ul>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n
\n
Ph\u1ee5 n\u1eef c\u00f3 thai<\/strong>: C\u00f3 th\u1ec3 g\u00e2y h\u1ea1i cho thai nhi, t\u0103ng nguy c\u01a1 d\u1ecb t\u1eadt b\u1ea9m sinh (\u0111\u1eb7c bi\u1ec7t h\u1edf h\u00e0m \u1ebfch), thai nh\u1ecf so v\u1edbi tu\u1ed5i thai. C\u00f3 th\u1ec3 g\u00e2y toan chuy\u1ec3n h\u00f3a trong thai k\u1ef3. Ph\u1ee5 n\u1eef trong \u0111\u1ed9 tu\u1ed5i sinh s\u1ea3n c\u1ea7n \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n v\u1ec1 bi\u1ec7n ph\u00e1p tr\u00e1nh thai hi\u1ec7u qu\u1ea3.<\/li>\n
B\u00e0 m\u1eb9 cho con b\u00fa<\/strong>: Topiramate b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9. \u0110\u00e3 c\u00f3 b\u00e1o c\u00e1o v\u1ec1 m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p tr\u1ebb b\u00fa m\u1eb9 b\u1ecb an th\u1ea7n v\u00e0 ti\u00eau ch\u1ea3y, nh\u01b0ng h\u1ea7u h\u1ebft tr\u1ebb s\u01a1 sinh dung n\u1ea1p thu\u1ed1c t\u1ed1t. C\u1ea7n theo d\u00f5i tr\u1ebb v\u1ec1 c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 ti\u00eau ch\u1ea3y, bu\u1ed3n ng\u1ee7, c\u00e1u k\u1ec9nh, t\u0103ng c\u00e2n \u0111\u1ea7y \u0111\u1ee7 v\u00e0 c\u00e1c m\u1ed1c ph\u00e1t tri\u1ec3n.<\/li>\n<\/ul>\n
L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n
Topiramate c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t, r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c, ho\u1eb7c c\u00e1c tri\u1ec7u ch\u1ee9ng kh\u00e1c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng t\u1eadp trung v\u00e0 ph\u1ed1i h\u1ee3p v\u1eadn \u0111\u1ed9ng. B\u1ec7nh nh\u00e2n c\u1ea7n th\u1eadn tr\u1ecdng khi l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c cho \u0111\u1ebfn khi h\u1ecd bi\u1ebft ch\u1eafc ch\u1eafn thu\u1ed1c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn m\u00ecnh nh\u01b0 th\u1ebf n\u00e0o.<\/p>\n
Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n
\n
Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u: Gi\u1ea3m nh\u1eadn th\u1ee9c, bu\u1ed3n ng\u1ee7 nghi\u00eam tr\u1ecdng, ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, k\u00edch \u0111\u1ed9ng t\u00e2m th\u1ea7n, co gi\u1eadt, r\u1ed1i lo\u1ea1n ng\u00f4n ng\u1eef, nh\u00ecn \u0111\u00f4i, kh\u00f3 kh\u0103n trong suy ngh\u0129, m\u1ea5t ph\u1ed1i h\u1ee3p v\u1eadn \u0111\u1ed9ng b\u1ea5t th\u01b0\u1eddng, h\u1ea1 huy\u1ebft \u00e1p, \u0111au b\u1ee5ng, tr\u1ea7m c\u1ea3m, \u0111\u1ed3ng t\u1eed gi\u00e3n.<\/li>\n
X\u1eed tr\u00ed: T\u00ecm ki\u1ebfm s\u1ef1 ch\u0103m s\u00f3c y t\u1ebf ngay l\u1eadp t\u1ee9c. Ng\u1eebng thu\u1ed1c v\u00e0 \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3, bao g\u1ed3m duy tr\u00ec th\u00f4ng kh\u00ed, b\u00f9 n\u01b0\u1edbc v\u00e0 theo d\u00f5i c\u00e1c d\u1ea5u hi\u1ec7u sinh t\u1ed3n. Topiramate c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf hi\u1ec7u qu\u1ea3 kh\u1ecfi huy\u1ebft t\u01b0\u01a1ng b\u1eb1ng th\u1ea9m ph\u00e2n m\u00e1u<\/li>\n<\/ul>\n
S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Huether-25<\/h2>\n
Thu\u1ed1c Topamax 25mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Topiramate v\u1edbi h\u00e0m l\u01b0\u1ee3ng 25mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Cilag AG \u2013 Th\u1ee5y S\u0129, thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u00e1c c\u01a1n \u0111\u1ed9ng kinh.<\/p>\n
T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n
J Bauer, S Schwalen. Topiramate (Topamax). Pharmacological characteristics and current use in epilepsy treatment, truy c\u1eadp ng\u00e0y 04 th\u00e1ng 07 n\u0103m 2025 t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/10919147\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"
Thu\u1ed1c Huether-25 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa (Davipharm), c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-29721-18, \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u1ed9ng kinh v\u00e0 d\u1ef1 ph\u00f2ng \u0111au n\u1eeda \u0111\u1ea7u.<\/p>\n","protected":false},"author":1,"featured_media":126001,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-125999","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/125999","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=125999"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/126001"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=125999"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=125999"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=125999"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

Ch\u1ec9 \u0111\u1ecbnh<\/td>\n	\u0110\u1ed1i t\u01b0\u1ee3ng<\/td>\n	Li\u1ec1u kh\u1edfi \u0111\u1ea7u<\/td>\n	T\u1ed1c \u0111\u1ed9 d\u00f2 li\u1ec1u<\/td>\n	Li\u1ec1u m\u1ee5c ti\u00eau\/duy tr\u00ec<\/td>\n	Li\u1ec1u t\u1ed1i \u0111a khuy\u1ebfn c\u00e1o<\/td>\n<\/tr>\n
\u0110\u01a1n tr\u1ecb li\u1ec7u \u0111\u1ed9ng kinh<\/td>\n	Ng\u01b0\u1eddi l\u1edbn<\/td>\n	25 mg\/ng\u00e0y (u\u1ed1ng bu\u1ed5i t\u1ed1i) trong 1 tu\u1ea7n<\/td>\n	T\u0103ng 25-50 mg\/ng\u00e0y m\u1ed7i 1-2 tu\u1ea7n, chia 2 l\u1ea7n<\/td>\n	Kho\u1ea3ng 400 mg\/ng\u00e0y, chia 2 l\u1ea7n<\/td>\n	1.000 mg\/ng\u00e0y (m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n kh\u00e1ng thu\u1ed1c dung n\u1ea1p)<\/td>\n<\/tr>\n
\u0110i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 \u0111\u1ed9ng kinh<\/td>\n	Tr\u1ebb em (\u2265 2 tu\u1ed5i)<\/td>\n	25 mg\/ng\u00e0y (u\u1ed1ng bu\u1ed5i t\u1ed1i) trong 1 tu\u1ea7n (ho\u1eb7c 1-3 mg\/kg\/ng\u00e0y)<\/td>\n	T\u0103ng 1-3 mg\/kg\/ng\u00e0y m\u1ed7i 1-2 tu\u1ea7n, chia 2 l\u1ea7n<\/td>\n	D\u00f2 li\u1ec1u trong 5-7 tu\u1ea7n \u0111\u1ec3 \u0111\u1ea1t li\u1ec1u duy tr\u00ec d\u1ef1a tr\u00ean c\u00e2n n\u1eb7ng<\/td>\n	30 mg\/kg\/ng\u00e0y (t\u1ed5ng li\u1ec1u kh\u00f4ng qu\u00e1 400 mg\/ng\u00e0y)<\/td>\n<\/tr>\n
Ng\u01b0\u1eddi l\u1edbn<\/td>\n	25-50 mg\/ng\u00e0y (u\u1ed1ng bu\u1ed5i t\u1ed1i) trong 1 tu\u1ea7n<\/td>\n	T\u0103ng 25-50 mg\/ng\u00e0y m\u1ed7i 1-2 tu\u1ea7n, chia 2 l\u1ea7n<\/td>\n	Kho\u1ea3ng 200-400 mg\/ng\u00e0y, chia 2 l\u1ea7n<\/td>\n	500 mg\/ng\u00e0y<\/td>\n<\/tr>\n
Tr\u1ebb em (\u2265 2 tu\u1ed5i)<\/td>\n	25 mg\/ng\u00e0y (u\u1ed1ng bu\u1ed5i t\u1ed1i) trong 1 tu\u1ea7n (ho\u1eb7c 1-3 mg\/kg\/ng\u00e0y)<\/td>\n	T\u0103ng 1-3 mg\/kg\/ng\u00e0y m\u1ed7i 1-2 tu\u1ea7n, chia 2 l\u1ea7n<\/td>\n	Kho\u1ea3ng 5-9 mg\/kg\/ng\u00e0y, chia 2 l\u1ea7n<\/td>\n	T\u1ed5ng li\u1ec1u kh\u00f4ng qu\u00e1 400 mg\/ng\u00e0y<\/td>\n<\/tr>\n
D\u1ef1 ph\u00f2ng \u0111au n\u1eeda \u0111\u1ea7u<\/td>\n	Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em (\u2265 12 tu\u1ed5i)<\/td>\n	25 mg\/ng\u00e0y (u\u1ed1ng bu\u1ed5i t\u1ed1i) trong 1 tu\u1ea7n<\/td>\n	T\u0103ng 25 mg\/ng\u00e0y m\u1ed7i tu\u1ea7n<\/td>\n	100 mg\/ng\u00e0y, chia 2 l\u1ea7n<\/td>\n	200 mg\/ng\u00e0y (c\u1ea7n th\u1eadn tr\u1ecdng do t\u0103ng t\u00e1c d\u1ee5ng ph\u1ee5)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Huether-25<\/h2>\n \n \u0110\u01b0\u1eddng d\u00f9ng: Thu\u1ed1c \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng.<\/li>\n Th\u1eddi \u0111i\u1ec3m d\u00f9ng thu\u1ed1c: C\u00f3 th\u1ec3 u\u1ed1ng m\u1ed9t l\u1ea7n ho\u1eb7c hai l\u1ea7n m\u1ed7i ng\u00e0y, th\u01b0\u1eddng khuy\u1ebfn c\u00e1o b\u1eaft \u0111\u1ea7u v\u00e0o bu\u1ed5i t\u1ed1i.<\/li>\n<\/ul>\n Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Huether-25 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n \n Qu\u00e1 m\u1eabn: B\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn v\u1edbi Topiramate ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi Metformin: Do t\u0103ng nguy c\u01a1 toan chuy\u1ec3n h\u00f3a.<\/li>\n S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf carbonic anhydrase kh\u00e1c: Tr\u00e1nh d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi acetazolamide, dorzolamide, brinzolamide do t\u0103ng nguy c\u01a1 toan chuy\u1ec3n h\u00f3a v\u00e0 s\u1ecfi th\u1eadn.<\/li>\n<\/ul>\n L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Huether-25<\/h2>\n Th\u1eadn tr\u1ecdng<\/h3>\n Ng\u1eebng thu\u1ed1c ch\u1ed1ng \u0111\u1ed9ng kinh (AEDs): N\u00ean ng\u1eebng t\u1eeb t\u1eeb \u0111\u1ec3 tr\u00e1nh nguy c\u01a1 t\u0103ng c\u01a1n \u0111\u1ed9ng kinh t\u00e1i ph\u00e1t.<\/p>\n T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n \n R\u1ea5t th\u01b0\u1eddng g\u1eb7p (>10%): D\u1ecb c\u1ea3m, ch\u00f3ng m\u1eb7t, bu\u1ed3n ng\u1ee7, ch\u00e1n \u0103n, gi\u1ea3m c\u00e2n, m\u1ec7t m\u1ecfi, ti\u00eau ch\u1ea3y, vi\u00eam m\u0169i h\u1ecdng, tr\u1ea7m c\u1ea3m.<\/li>\n Th\u01b0\u1eddng g\u1eb7p (1% \u0111\u1ebfn 10%): Lo l\u1eafng, ch\u1eadm v\u1eadn \u0111\u1ed9ng t\u00e2m th\u1ea7n, kh\u00f3 kh\u0103n v\u1ec1 tr\u00ed nh\u1edb, kh\u00f3 t\u1eadp trung, r\u1ed1i lo\u1ea1n ng\u00f4n ng\u1eef, thay \u0111\u1ed5i v\u1ecb gi\u00e1c, bu\u1ed3n n\u00f4n, \u0111au b\u1ee5ng, s\u1ed1t, m\u1edd m\u1eaft, m\u1ea5t ng\u1ee7, y\u1ebfu c\u01a1, kh\u00f4 mi\u1ec7ng, t\u00e1o b\u00f3n, vi\u00eam ph\u1ebf qu\u1ea3n, \u0111au kh\u1edbp, ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn.<\/li>\n \u00cdt g\u1eb7p (0.1% \u0111\u1ebfn 1%): K\u00edch \u0111\u1ed9ng, c\u00e1u k\u1ec9nh, \u0111au ng\u1ef1c, gi\u1ea3m c\u1ea3m gi\u00e1c, m\u1ea5t h\u1ee9ng th\u00fa, ch\u1ea3y m\u00e1u n\u01b0\u1edbu, \u0111au h\u1ecdng, ph\u00f9 m\u1ea1ch, s\u01b0ng kh\u1edbp, kh\u00f3 th\u1edf khi g\u1eafng s\u1ee9c.<\/li>\n Hi\u1ebfm g\u1eb7p (<0.1%): M\u00e1u trong n\u01b0\u1edbc ti\u1ec3u, \u0111i ti\u1ec3u kh\u00f3\/\u0111au, m\u1ea5t th\u00ednh l\u1ef1c, ng\u1ee9a, ph\u00e1t ban da, m\u1ea5t ki\u1ec3m so\u00e1t b\u00e0ng quang, \u0111au l\u01b0ng d\u01b0\u1edbi, ch\u1ea3y m\u00e1u cam, da xanh xao, \u00f9 tai, s\u01b0ng, kh\u00f3 th\u1edf, kh\u00f3 ch\u1ecbu \u1edf chi.<\/li>\n<\/ul>\n T\u01b0\u01a1ng t\u00e1c<\/h3>\n \n Thu\u1ed1c ng\u1eeba thai \u0111\u01b0\u1eddng u\u1ed1ng: C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a thu\u1ed1c, \u0111\u1eb7c bi\u1ec7t \u1edf li\u1ec1u tr\u00ean 200 mg\/ng\u00e0y.<\/li>\n C\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u1ed9ng kinh kh\u00e1c (AEDs):\n \n Acid Valproic: C\u00f3 th\u1ec3 g\u00e2y h\u1ea1 th\u00e2n nhi\u1ec7t, m\u1ec7t m\u1ecfi, l\u00fa l\u1eabn, t\u0103ng n\u1ed3ng \u0111\u1ed9 amoniac trong m\u00e1u.<\/li>\n Carbamazepine: C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 Topiramate trong huy\u1ebft t\u01b0\u01a1ng.<\/li>\n Zonisamide: T\u0103ng nguy c\u01a1 v\u00e0 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a toan chuy\u1ec3n h\u00f3a.<\/li>\n<\/ul>\n<\/li>\n Thu\u1ed1c \u1ee9c ch\u1ebf carbonic anhydrase kh\u00e1c: Tr\u00e1nh d\u00f9ng \u0111\u1ed3ng th\u1eddi do t\u0103ng nguy c\u01a1 toan chuy\u1ec3n h\u00f3a v\u00e0 s\u1ecfi th\u1eadn.<\/li>\n Thu\u1ed1c \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng: C\u00f3 th\u1ec3 g\u00e2y an th\u1ea7n v\u00e0 \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng qu\u00e1 m\u1ee9c.<\/li>\n Metformin: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi do t\u0103ng nguy c\u01a1 toan chuy\u1ec3n h\u00f3a.<\/li>\n Lithium: N\u1ed3ng \u0111\u1ed9 lithium c\u00f3 th\u1ec3 t\u0103ng khi d\u00f9ng Topiramate li\u1ec1u cao (600 mg\/ng\u00e0y).<\/li>\n Amitriptyline: \u0110\u1ed9 thanh th\u1ea3i c\u1ee7a Topiramate c\u00f3 th\u1ec3 gi\u1ea3m.<\/li>\n T\u01b0\u01a1ng t\u00e1c v\u1edbi th\u1ef1c ph\u1ea9m\/\u0111\u1ed3 u\u1ed1ng: R\u01b0\u1ee3u (Ethanol): Kh\u00f4ng n\u00ean u\u1ed1ng r\u01b0\u1ee3u khi \u0111ang d\u00f9ng Topiramate v\u00ec c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n ng\u1ee7 qu\u00e1 m\u1ee9c, l\u00fa l\u1eabn, kh\u00f3 kh\u0103n v\u1ec1 tr\u00ed nh\u1edb ho\u1eb7c l\u1eddi n\u00f3i, v\u00e0 t\u0103ng nguy c\u01a1 co gi\u1eadt.<\/li>\n<\/ul>\n L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n \n Ph\u1ee5 n\u1eef c\u00f3 thai<\/strong>: C\u00f3 th\u1ec3 g\u00e2y h\u1ea1i cho thai nhi, t\u0103ng nguy c\u01a1 d\u1ecb t\u1eadt b\u1ea9m sinh (\u0111\u1eb7c bi\u1ec7t h\u1edf h\u00e0m \u1ebfch), thai nh\u1ecf so v\u1edbi tu\u1ed5i thai. C\u00f3 th\u1ec3 g\u00e2y toan chuy\u1ec3n h\u00f3a trong thai k\u1ef3. Ph\u1ee5 n\u1eef trong \u0111\u1ed9 tu\u1ed5i sinh s\u1ea3n c\u1ea7n \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n v\u1ec1 bi\u1ec7n ph\u00e1p tr\u00e1nh thai hi\u1ec7u qu\u1ea3.<\/li>\n B\u00e0 m\u1eb9 cho con b\u00fa<\/strong>: Topiramate b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9. \u0110\u00e3 c\u00f3 b\u00e1o c\u00e1o v\u1ec1 m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p tr\u1ebb b\u00fa m\u1eb9 b\u1ecb an th\u1ea7n v\u00e0 ti\u00eau ch\u1ea3y, nh\u01b0ng h\u1ea7u h\u1ebft tr\u1ebb s\u01a1 sinh dung n\u1ea1p thu\u1ed1c t\u1ed1t. C\u1ea7n theo d\u00f5i tr\u1ebb v\u1ec1 c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 ti\u00eau ch\u1ea3y, bu\u1ed3n ng\u1ee7, c\u00e1u k\u1ec9nh, t\u0103ng c\u00e2n \u0111\u1ea7y \u0111\u1ee7 v\u00e0 c\u00e1c m\u1ed1c ph\u00e1t tri\u1ec3n.<\/li>\n<\/ul>\n L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n Topiramate c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t, r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c, ho\u1eb7c c\u00e1c tri\u1ec7u ch\u1ee9ng kh\u00e1c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng t\u1eadp trung v\u00e0 ph\u1ed1i h\u1ee3p v\u1eadn \u0111\u1ed9ng. B\u1ec7nh nh\u00e2n c\u1ea7n th\u1eadn tr\u1ecdng khi l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c cho \u0111\u1ebfn khi h\u1ecd bi\u1ebft ch\u1eafc ch\u1eafn thu\u1ed1c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn m\u00ecnh nh\u01b0 th\u1ebf n\u00e0o.<\/p>\n Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n \n Tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u: Gi\u1ea3m nh\u1eadn th\u1ee9c, bu\u1ed3n ng\u1ee7 nghi\u00eam tr\u1ecdng, ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, k\u00edch \u0111\u1ed9ng t\u00e2m th\u1ea7n, co gi\u1eadt, r\u1ed1i lo\u1ea1n ng\u00f4n ng\u1eef, nh\u00ecn \u0111\u00f4i, kh\u00f3 kh\u0103n trong suy ngh\u0129, m\u1ea5t ph\u1ed1i h\u1ee3p v\u1eadn \u0111\u1ed9ng b\u1ea5t th\u01b0\u1eddng, h\u1ea1 huy\u1ebft \u00e1p, \u0111au b\u1ee5ng, tr\u1ea7m c\u1ea3m, \u0111\u1ed3ng t\u1eed gi\u00e3n.<\/li>\n X\u1eed tr\u00ed: T\u00ecm ki\u1ebfm s\u1ef1 ch\u0103m s\u00f3c y t\u1ebf ngay l\u1eadp t\u1ee9c. Ng\u1eebng thu\u1ed1c v\u00e0 \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3, bao g\u1ed3m duy tr\u00ec th\u00f4ng kh\u00ed, b\u00f9 n\u01b0\u1edbc v\u00e0 theo d\u00f5i c\u00e1c d\u1ea5u hi\u1ec7u sinh t\u1ed3n. Topiramate c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf hi\u1ec7u qu\u1ea3 kh\u1ecfi huy\u1ebft t\u01b0\u01a1ng b\u1eb1ng th\u1ea9m ph\u00e2n m\u00e1u<\/li>\n<\/ul>\n S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Huether-25<\/h2>\n Thu\u1ed1c Topamax 25mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Topiramate v\u1edbi h\u00e0m l\u01b0\u1ee3ng 25mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Cilag AG \u2013 Th\u1ee5y S\u0129, thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng \u0111i\u1ec1u tr\u1ecb c\u00e1c c\u01a1n \u0111\u1ed9ng kinh.<\/p>\n T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n J Bauer, S Schwalen. Topiramate (Topamax). Pharmacological characteristics and current use in epilepsy treatment, truy c\u1eadp ng\u00e0y 04 th\u00e1ng 07 n\u0103m 2025 t\u1eeb https:\/\/pubmed.ncbi.nlm.nih.gov\/10919147\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":" Thu\u1ed1c Huether-25 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa (Davipharm), c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VD-29721-18, \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u1ed9ng kinh v\u00e0 d\u1ef1 ph\u00f2ng \u0111au n\u1eeda \u0111\u1ea7u.<\/p>\n","protected":false},"author":1,"featured_media":126001,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-125999","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/125999","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=125999"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/126001"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=125999"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=125999"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=125999"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Huether-25<\/h2>\n

L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Huether-25<\/h2>\n

Th\u1eadn tr\u1ecdng<\/h3>\nNg\u1eebng thu\u1ed1c ch\u1ed1ng \u0111\u1ed9ng kinh (AEDs): N\u00ean ng\u1eebng t\u1eeb t\u1eeb \u0111\u1ec3 tr\u00e1nh nguy c\u01a1 t\u0103ng c\u01a1n \u0111\u1ed9ng kinh t\u00e1i ph\u00e1t.<\/p>\n

Th\u1eadn tr\u1ecdng<\/h3>\n
Ng\u1eebng thu\u1ed1c ch\u1ed1ng \u0111\u1ed9ng kinh (AEDs): N\u00ean ng\u1eebng t\u1eeb t\u1eeb \u0111\u1ec3 tr\u00e1nh nguy c\u01a1 t\u0103ng c\u01a1n \u0111\u1ed9ng kinh t\u00e1i ph\u00e1t.<\/p>\n