{"id":125808,"date":"2025-07-03T15:35:43","date_gmt":"2025-07-03T08:35:43","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=125808"},"modified":"2025-12-23T10:23:35","modified_gmt":"2025-12-23T03:23:35","slug":"feleilor-90mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/feleilor-90mg\/","title":{"rendered":"Feleilor 90mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Feleilor \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Medisun, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110596524 (VD-33473-19).<\/strong><\/p>\n<h2>Feleilor 90mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i vi\u00ean thu\u1ed1c <strong>Feleilor 90mg<\/strong> g\u1ed3m c\u00f3<strong> Ticagrelor<\/strong> v\u1edbi h\u00e0m l\u01b0\u1ee3ng 90mg.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110596524 (VD-33473-19)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_125813\" aria-describedby=\"caption-attachment-125813\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-125813\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/thuoc-feleilor-90mg-4.jpg\" alt=\"Feleilor 90mg ph\u00f2ng ng\u1eeba x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch, nh\u1ed3i m\u00e1u c\u01a1 tim\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/thuoc-feleilor-90mg-4.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/thuoc-feleilor-90mg-4-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/thuoc-feleilor-90mg-4-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/07\/thuoc-feleilor-90mg-4-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-125813\" class=\"wp-caption-text\">Feleilor 90mg ph\u00f2ng ng\u1eeba x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch, nh\u1ed3i m\u00e1u c\u01a1 tim<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Feleilor 90mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Ticagrelor l\u00e0 thu\u1ed1c kh\u00e1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u, thu\u1ed9c nh\u00f3m cyclopentyltriazolopyrimidin (CPTP), ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 P2Y12 tr\u00ean b\u1ec1 m\u1eb7t ti\u1ec3u c\u1ea7u. B\u00ecnh th\u01b0\u1eddng, khi ADP g\u1eafn v\u00e0o th\u1ee5 th\u1ec3 n\u00e0y s\u1ebd k\u00edch th\u00edch ti\u1ec3u c\u1ea7u k\u1ebft d\u00ednh v\u00e0 h\u00ecnh th\u00e0nh c\u1ee5c m\u00e1u \u0111\u00f4ng. Do \u0111\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ed1i kh\u00e1ng c\u1ee7a Ticagrelor s\u1ebd ng\u0103n ch\u1eb7n qu\u00e1 tr\u00ecnh n\u00e0y, gi\u00fap gi\u1ea3m nguy c\u01a1 h\u00ecnh th\u00e0nh huy\u1ebft kh\u1ed1i trong \u0111\u1ed9ng m\u1ea1ch v\u00e0nh. Ticagrelor c\u00f3 t\u00e1c d\u1ee5ng nhanh v\u00e0 m\u1ea1nh, kh\u1ea3 n\u0103ng ph\u1ee5c h\u1ed3i ch\u1ee9c n\u0103ng ti\u1ec3u c\u1ea7u nhanh h\u01a1n so v\u1edbi c\u00e1c thu\u1ed1c ch\u1ed1ng t\u1eadp k\u1ebft kh\u00e1c nh\u01b0 clopidogrel, aspirin.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu: nhanh ch\u00f3ng \u0111\u01b0\u1ee3c h\u1ea5p thu sau khi u\u1ed1ng, th\u1eddi gian tmax kho\u1ea3ng 1,5 gi\u1edd, v\u00e0 v\u1edbi li\u1ec1u u\u1ed1ng 90mg \u0111o \u0111\u01b0\u1ee3c c\u00e1c gi\u00e1 tr\u1ecb AUC, Cmax l\u1ea7n l\u01b0\u1ee3ng l\u00e0 3,451 ng*h\/ml, 529 ng\/ml.<\/li>\n<li>Ph\u00e2n b\u1ed1: t\u1ef7 l\u1ec7 li\u00ean k\u1ebft v\u1edbi protein r\u1ea5t cao v\u00e0 th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 \u0111o \u0111\u01b0\u1ee3c kho\u1ea3ng 87,5L.<\/li>\n<li>Chuy\u1ec3n ho\u00e1: qua gan nh\u1edd enzym CYP3A4.<\/li>\n<li>Th\u1ea3i tr\u1eeb: ph\u1ea7n l\u1edbn thu\u1ed1c t\u00ecm th\u1ea5y trong ph\u00e2n, ngo\u00e0i ra ph\u1ea7n nh\u1ecf t\u00ecm th\u1ea5y trong n\u01b0\u1edbc ti\u1ec3u.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Feleilor 90mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Thu\u1ed1c \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh ph\u00f2ng ng\u1eeba c\u00e1c bi\u1ebfn c\u1ed1 c\u1ee5c m\u00e1u \u0111\u00f4ng do x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch \u1edf ng\u01b0\u1eddi cao tu\u1ed5i trong tr\u01b0\u1eddng h\u1ee3p:<\/p>\n<ul>\n<li>H\u1ed9i ch\u1ee9ng m\u1ea1ch v\u00e0nh c\u1ea5p (ACS)<\/li>\n<li>Ti\u1ec1n s\u1eed nh\u1ed3i m\u00e1u c\u01a1 tim<\/li>\n<li>Ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 huy\u1ebft kh\u1ed1i \u0111\u1ed9ng m\u1ea1ch<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Feleilor 90mg<\/h2>\n<ul>\n<li>Kh\u1edfi \u0111\u1ea7u v\u1edbi li\u1ec1u 2 vi\u00ean\/l\u1ea7n x 1 l\u1ea7n duy nh\u1ea5t (t\u01b0\u01a1ng \u0111\u01b0\u01a1ng li\u1ec1u 180mg\/l\u1ea7n).<\/li>\n<li>Sau \u0111\u00f3 duy tr\u00ec li\u1ec1u 90mg chia 2 l\u1ea7n u\u1ed1ng m\u1ed7i ng\u00e0y.<\/li>\n<li>K\u1ebft h\u1ee3p thu\u1ed1c v\u1edbi aspirin li\u1ec1u th\u1ea5p h\u00e0ng ng\u00e0y, th\u00f4ng th\u01b0\u1eddng t\u1eeb 75-100mg.<\/li>\n<\/ul>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Feleilor 90mg<\/h2>\n<p>D\u00f9ng thu\u1ed1c Feleilor b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng, c\u00f3 th\u1ec3 u\u1ed1ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng th\u1ee9c \u0103n.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Feleilor 90mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>M\u1eabn c\u1ea3m v\u1edbi c\u00e1c th\u00e0nh ph\u1ea7n trong thu\u1ed1c Feleilor.<\/li>\n<li>B\u1ec7nh nh\u00e2n \u0111ang b\u1ecb ch\u1ea3y m\u00e1u do nguy\u00ean nh\u00e2n b\u1ec7nh l\u00fd.<\/li>\n<li>Ti\u1ec1n s\u1eed ch\u1ea3y m\u00e1u n\u00e3o.<\/li>\n<li>Suy gan.<\/li>\n<li>\u0110ang s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf m\u1ea1nh CYP3A4.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Feleilor 90mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Xu h\u01b0\u1edbng t\u0103ng ch\u1ea3y m\u00e1u khi s\u1eed d\u1ee5ng thu\u1ed1c, n\u00ean c\u1ea7n th\u1eadn tr\u1ecdng v\u1edbi nh\u1eefng \u0111\u1ed1i t\u01b0\u1ee3ng nguy c\u01a1 cao nh\u01b0 ti\u1ec1n s\u1eed xu\u1ea5t huy\u1ebft d\u1ea1 d\u00e0y, hay \u0111ang d\u00f9ng c\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u, b\u1ecb ch\u1ea5n th\u01b0\u01a1ng nghi\u00eam tr\u1ecdng.<\/li>\n<li>S\u1eed d\u1ee5ng \u0111\u00fang li\u1ec1u l\u01b0\u1ee3ng, h\u01b0\u1edbng d\u1eabn c\u1ee7a b\u00e1c s\u0129 \u0111\u1ec3 tr\u00e1nh g\u1eb7p t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng.<\/li>\n<li>Kh\u00f4ng t\u1ef1 \u00fd ng\u01b0ng \u0111\u1ed9t ng\u1ed9t thu\u1ed1c do t\u0103ng nguy c\u01a1 nh\u1ed3i m\u00e1u c\u01a1 tim, huy\u1ebft kh\u1ed1i, th\u1eadm ch\u00ed t\u1eed vong.<\/li>\n<li>Tr\u1ebb d\u01b0\u1edbi 18 tu\u1ed5i kh\u00f4ng c\u00f3 khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng thu\u1ed1c Feleilor 90mg.<\/li>\n<li>Th\u1eadn tr\u1ecdng \u1edf \u0111\u1ed1i t\u01b0\u1ee3ng b\u1ecb hen suy\u1ec5n, g\u1eb7p c\u00e1c b\u1ec7nh l\u00fd v\u1ec1 ph\u1ed5i, nh\u1ecbp tim gi\u1ea3m d\u01b0\u1edbi 60 nh\u1ecbp\/ ph\u00fat b\u1ea5t th\u01b0\u1eddng.<\/li>\n<li>K\u1ebft qu\u1ea3 x\u00e9t nghi\u1ec7m acid uric trong m\u00e1u c\u00f3 th\u1ec3 t\u0103ng cao so v\u1edbi th\u00f4ng th\u01b0\u1eddng khi b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng thu\u1ed1c.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>Th\u01b0\u1eddng g\u1eb7p: kh\u00f3 th\u1edf, ch\u1ea3y m\u00e1u cam, xu\u1ea5t huy\u1ebft ti\u00eau ho\u00e1, b\u1ea7m t\u00edm.<\/li>\n<li>\u00cdt g\u1eb7p: ch\u1ea3y m\u00e1u trong s\u1ecd, ho ra m\u00e1u, n\u00f4n ra m\u00e1u, bu\u1ed3n n\u00f4n, kh\u00f3 ti\u00eau, ban, ng\u1ee9a, ch\u1ea3y m\u00e1u \u00e2m \u0111\u1ea1o, qu\u00e1 m\u1eabn.<\/li>\n<li>Hi\u1ebfm g\u1eb7p: t\u0103ng creatinin m\u00e1u, t\u00e1o b\u00f3n, xu\u1ea5t huy\u1ebft ph\u00fac m\u1ea1c, d\u1ecb c\u1ea3m, l\u00fa l\u1eabn, t\u0103ng acid uric.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf CYP3A4 m\u1ea1nh (v\u00ed d\u1ee5 nh\u01b0 ketoconazole,clarithromycin, nefazodone) : Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng \u0111\u1ed3ng th\u1eddi do l\u00e0m t\u0103ng m\u1ee9c ti\u1ebfp x\u00fac v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a ticagrelor.<\/li>\n<li>Thu\u1ed1c c\u1ea3m \u1ee9ng CYP3A4, thu\u1ed1c tr\u00e1nh thai, n\u01b0\u1edbc \u00e9p b\u01b0\u1edfi: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng \u0111\u1ed3ng th\u1eddi do l\u00e0m gi\u1ea3m m\u1ee9c ti\u1ebfp x\u00fac v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a ticagrelor.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Thu\u1ed1c Feleilor 90mg kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng cho nh\u1eefng \u0111\u1ed1i t\u01b0\u1ee3ng mang thai ho\u1eb7c \u0111ang cho con b\u00fa.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>N\u00ean th\u1eadn tr\u1ecdng \u1edf \u0111\u1ed1i t\u01b0\u1ee3ng t\u1eebng b\u1ecb ch\u00f3ng m\u1eb7t khi d\u00f9ng thu\u1ed1c trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh m\u1ea1ch v\u00e0nh c\u1ea5p.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>D\u1ea5u hi\u1ec7u l\u00e2m s\u00e0ng nh\u1eadn bi\u1ebft qu\u00e1 li\u1ec1u nh\u01b0 kh\u00f3 th\u1edf, ng\u01b0ng th\u1ea5t. Ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u n\u00ean c\u1ea7n \u0111\u01b0a b\u1ec7nh nh\u00e2n \u0111\u1ebfn c\u01a1 s\u1edf c\u1ea5p c\u1ee9u v\u00e0 h\u1ed7 tr\u1ee3 s\u1edbm nh\u1ea5t.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Feleilor<\/h2>\n<p><a href=\"https:\/\/vnras.com\/drug\/ticagrelor-alkem-90mg\/\">Ticagrelor Alkem 90mg<\/a> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n ch\u00ednh Ticagrelor 90mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty Alkem Laboratories Ltd. \u1ea4n \u0110\u1ed9, ph\u00f2ng ng\u1eeba nguy c\u01a1 huy\u1ebft kh\u1ed1i m\u1ea1ch v\u00e0nh, nh\u1ed3i m\u00e1u c\u01a1 tim.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Paul P Dobesh, Julie H Oestreich. Ticagrelor: Pharmacokinetics, Pharmacodynamics, Clinical Efficacy, and Safety, truy c\u1eadp ng\u00e0y 03 th\u00e1ng 07 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4282310\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4282310\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Feleilor \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Medisun, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110596524 (VD-33473-19), ch\u1ed1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u m\u1ea1nh, ph\u00f2ng ng\u1eeba nh\u1ed3i m\u00e1u c\u01a1 tim.<\/p>\n","protected":false},"author":1,"featured_media":125810,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-125808","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/125808","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=125808"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/125810"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=125808"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=125808"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=125808"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}