{"id":125142,"date":"2025-06-27T23:55:45","date_gmt":"2025-06-27T16:55:45","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=125142"},"modified":"2025-12-23T11:17:22","modified_gmt":"2025-12-23T04:17:22","slug":"irinotel-100mg-5ml","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/irinotel-100mg-5ml\/","title":{"rendered":"Irinotel 100mg\/5ml"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Irinotel 100mg\/5ml \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Fresenius Kabi Oncology Ltd, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 890114071323.<\/strong><\/p>\n<h2>Irinotel 100mg\/5ml l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Irinotel 100mg\/5ml<\/strong> l\u00e0 thu\u1ed1c h\u00f3a tr\u1ecb li\u1ec7u m\u1ea1nh c\u00f3 th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li>Ho\u1ea1t ch\u1ea5t: M\u1ed7i milil\u00edt dung d\u1ecbch \u0111\u1eadm \u0111\u1eb7c ch\u1ee9a 20 mg <strong>Irinotecan<\/strong> hydrochloride trihydrate, t\u01b0\u01a1ng \u0111\u01b0\u01a1ng 17.33 mg irinotecan base.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 890114071323<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd 5ml<\/p>\n<p>Xu\u1ea5t x\u1ee9: India<\/p>\n<figure id=\"attachment_125146\" aria-describedby=\"caption-attachment-125146\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-125146\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Irinotel-100mg5ml.jpg\" alt=\"Irinotel 100mg\/5ml thu\u1ed1c h\u00f3a tr\u1ecb li\u1ec7u ung th\u01b0\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Irinotel-100mg5ml.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Irinotel-100mg5ml-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Irinotel-100mg5ml-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Irinotel-100mg5ml-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-125146\" class=\"wp-caption-text\">Irinotel 100mg\/5ml thu\u1ed1c h\u00f3a tr\u1ecb li\u1ec7u ung th\u01b0<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Irinotel 100mg\/5ml<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Irinotecan l\u00e0 ti\u1ec1n ch\u1ea5t, \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a th\u00e0nh ch\u1ea5t ho\u1ea1t t\u00ednh SN-38. SN-38 \u1ee9c ch\u1ebf enzyme DNA topoisomerase I, g\u00e2y \u0111\u1ee9t g\u00e3y DNA v\u0129nh vi\u1ec5n, l\u00e0m ng\u1eebng chu tr\u00ecnh t\u1ebf b\u00e0o v\u00e0 k\u00edch ho\u1ea1t apoptosis \u1edf t\u1ebf b\u00e0o ung th\u01b0.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu: Truy\u1ec1n t\u0129nh m\u1ea1ch. N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh irinotecan \u0111\u1ea1t ngay sau truy\u1ec1n, SN-38 \u0111\u1ea1t sau 1-2 gi\u1edd.<\/li>\n<li>Ph\u00e2n b\u1ed1: Irinotecan li\u00ean k\u1ebft 30-68% v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng, SN-38 li\u00ean k\u1ebft m\u1ea1nh h\u01a1n (~95%).<\/li>\n<li>Chuy\u1ec3n h\u00f3a: Irinotecan th\u00e0nh SN-38 (ho\u1ea1t h\u00f3a), SN-38 th\u00e0nh SN-38G (b\u1ea5t ho\u1ea1t) b\u1edfi UGT1A1. C\u0169ng \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a b\u1edfi CYP3A4.<\/li>\n<li>Th\u1ea3i tr\u1eeb: Ch\u1ee7 y\u1ebfu qua m\u1eadt, m\u1ed9t ph\u1ea7n qua n\u01b0\u1edbc ti\u1ec3u. Chu tr\u00ecnh gan-ru\u1ed9t c\u1ee7a SN-38 g\u00f3p ph\u1ea7n g\u00e2y ti\u00eau ch\u1ea3y mu\u1ed9n.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Irinotel 100mg\/5ml \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<ul>\n<li><strong>Ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng di c\u0103n (mCRC):<\/strong> Ch\u1ec9 \u0111\u1ecbnh ch\u00ednh.\n<ul>\n<li><strong>B\u01b0\u1edbc m\u1ed9t:<\/strong> Th\u01b0\u1eddng ph\u1ed1i h\u1ee3p FOLFIRI (v\u1edbi 5-FU v\u00e0 leucovorin), c\u00f3 th\u1ec3 th\u00eam bevacizumab ho\u1eb7c cetuximab.<\/li>\n<li><strong>B\u01b0\u1edbc hai:<\/strong> \u0110\u01a1n tr\u1ecb li\u1ec7u ho\u1eb7c FOLFIRI cho b\u1ec7nh nh\u00e2n ti\u1ebfn tri\u1ec3n.<\/li>\n<\/ul>\n<\/li>\n<li><strong>Ung th\u01b0 t\u1ee5y di c\u0103n:<\/strong> Th\u01b0\u1eddng ph\u1ed1i h\u1ee3p v\u1edbi 5-FU v\u00e0 leucovorin.<\/li>\n<li><strong>C\u00e1c ch\u1ec9 \u0111\u1ecbnh kh\u00e1c:<\/strong> Nghi\u00ean c\u1ee9u v\u00e0 s\u1eed d\u1ee5ng (\u0111\u00f4i khi off-label) trong ung th\u01b0 ph\u1ed5i t\u1ebf b\u00e0o nh\u1ecf, ung th\u01b0 bu\u1ed3ng tr\u1ee9ng, ung th\u01b0 d\u1ea1 d\u00e0y.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Irinotel 100mg\/5ml<\/h2>\n<p>Li\u1ec1u t\u00ednh theo di\u1ec7n t\u00edch b\u1ec1 m\u1eb7t c\u01a1 th\u1ec3 (mg\/m2), ph\u1ee5 thu\u1ed9c ph\u00e1c \u0111\u1ed3 v\u00e0 th\u1ec3 tr\u1ea1ng.<\/p>\n<ul>\n<li>M\u1ed9t s\u1ed1 ph\u00e1c \u0111\u1ed3 ph\u1ed5 bi\u1ebfn:\n<ul>\n<li>\u0110\u01a1n tr\u1ecb (3 tu\u1ea7n\/l\u1ea7n): 350 mg\/m2.<\/li>\n<li>\u0110\u01a1n tr\u1ecb (h\u00e0ng tu\u1ea7n): 125 mg\/m2 (4 tu\u1ea7n, ngh\u1ec9 2 tu\u1ea7n).<\/li>\n<li>FOLFIRI: 180 mg\/m2 (2 tu\u1ea7n\/l\u1ea7n).<\/li>\n<\/ul>\n<\/li>\n<li>Hi\u1ec7u ch\u1ec9nh li\u1ec1u: B\u1eaft bu\u1ed9c gi\u1ea3m li\u1ec1u khi \u0111\u1ed9c t\u00ednh n\u1eb7ng (\u0111\u1ed9 3-4). Ti\u1ebfp t\u1ee5c chu k\u1ef3 khi \u0111\u1ed9c t\u00ednh gi\u1ea3m v\u1ec1 \u0111\u1ed9 1 ho\u1eb7c h\u1ed3i ph\u1ee5c.<\/li>\n<\/ul>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Irinotel 100mg\/5ml<\/h2>\n<ul>\n<li>An to\u00e0n: Do l\u00e0 thu\u1ed1c \u0111\u1ed9c t\u1ebf b\u00e0o, vi\u1ec7c pha ch\u1ebf v\u00e0 s\u1eed d\u1ee5ng ph\u1ea3i do nh\u00e2n vi\u00ean y t\u1ebf \u0111\u01b0\u1ee3c \u0111\u00e0o t\u1ea1o, trong \u0111i\u1ec1u ki\u1ec7n v\u00f4 khu\u1ea9n v\u00e0 tu\u00e2n th\u1ee7 quy tr\u00ecnh an to\u00e0n.<\/li>\n<li>Pha lo\u00e3ng: Ph\u1ea3i pha lo\u00e3ng v\u1edbi Dung d\u1ecbch Glucose 5% ho\u1eb7c Natri Clorid 0.9%.<\/li>\n<li>C\u00e1ch truy\u1ec1n: Ch\u1ec9 d\u00f9ng \u0111\u01b0\u1eddng truy\u1ec1n t\u0129nh m\u1ea1ch trong 90 ph\u00fat (c\u00f3 th\u1ec3 30-90 ph\u00fat). Truy\u1ec1n nhanh t\u0103ng nguy c\u01a1 t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ea5p t\u00ednh.<\/li>\n<li>D\u1ef1 ph\u00f2ng t\u00e1c d\u1ee5ng ph\u1ee5:\n<ul>\n<li>Bu\u1ed3n n\u00f4n\/n\u00f4n: D\u00f9ng thu\u1ed1c ch\u1ed1ng n\u00f4n d\u1ef1 ph\u00f2ng (corticosteroid + \u0111\u1ed1i kh\u00e1ng 5-HT3).<\/li>\n<li>H\u1ed9i ch\u1ee9ng Cholinergic c\u1ea5p (Ti\u00eau ch\u1ea3y s\u1edbm): \u0110i\u1ec1u tr\u1ecb b\u1eb1ng Atropine sulfate ti\u00eam d\u01b0\u1edbi da\/t\u0129nh m\u1ea1ch.<\/li>\n<li>Ti\u00eau ch\u1ea3y mu\u1ed9n: Gi\u00e1o d\u1ee5c b\u1ec7nh nh\u00e2n quan tr\u1ecdng nh\u1ea5t. B\u1ec7nh nh\u00e2n ph\u1ea3i c\u00f3 s\u1eb5n Loperamide, d\u00f9ng ngay khi c\u00f3 d\u1ea5u hi\u1ec7u: 4mg ban \u0111\u1ea7u, sau \u0111\u00f3 2mg m\u1ed7i 2 gi\u1edd cho \u0111\u1ebfn khi h\u1ebft ti\u00eau ch\u1ea3y 12 gi\u1edd.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Irinotel 100mg\/5ml trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Ti\u1ec1n s\u1eed ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn n\u1eb7ng v\u1edbi irinotecan ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>B\u1ec7nh vi\u00eam ru\u1ed9t m\u1ea1n t\u00ednh v\u00e0\/ho\u1eb7c t\u1eafc ru\u1ed9t.<\/li>\n<li>Ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa.<\/li>\n<li>B\u1ec7nh nh\u00e2n c\u00f3 n\u1ed3ng \u0111\u1ed9 bilirubin trong m\u00e1u cao h\u01a1n 3 l\u1ea7n gi\u1edbi h\u1ea1n tr\u00ean c\u1ee7a m\u1ee9c b\u00ecnh th\u01b0\u1eddng.<\/li>\n<li>Suy t\u1ee7y n\u1eb7ng.<\/li>\n<li>Ch\u1ec9 s\u1ed1 to\u00e0n tr\u1ea1ng theo thang \u0111i\u1ec3m WHO PS &gt; 2.<\/li>\n<li>S\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi v\u1edbi St. John\u2019s Wort (Hypericum perforatum).<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Irinotel 100mg\/5ml<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Ti\u00eau ch\u1ea3y n\u1eb7ng: C\u00f3 th\u1ec3 \u0111e d\u1ecda t\u00ednh m\u1ea1ng, \u0111\u1eb7c bi\u1ec7t ti\u00eau ch\u1ea3y mu\u1ed9n. C\u1ea7n x\u1eed tr\u00ed ngay b\u1eb1ng loperamide li\u1ec1u cao.<\/li>\n<li>Gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh n\u1eb7ng: Nguy hi\u1ec3m, c\u00f3 th\u1ec3 g\u00e2y nhi\u1ec5m tr\u00f9ng huy\u1ebft t\u1eed vong. Theo d\u00f5i c\u00f4ng th\u1ee9c m\u00e1u h\u00e0ng tu\u1ea7n. Ng\u1eebng ho\u1eb7c gi\u1ea3m li\u1ec1u n\u1ebfu s\u1ed1t gi\u1ea3m b\u1ea1ch c\u1ea7u ho\u1eb7c ANC &lt;1.0\u00d7109\/L. Nguy c\u01a1 t\u0103ng \u1edf b\u1ec7nh nh\u00e2n c\u00f3 ki\u1ec3u gen UGT1A1*28 \u0111\u1ed3ng h\u1ee3p t\u1eed.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>R\u1ea5t th\u01b0\u1eddng g\u1eb7p (&gt;1\/10): Ti\u00eau ch\u1ea3y mu\u1ed9n, bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, ch\u00e1n \u0103n, vi\u00eam ni\u00eam m\u1ea1c, suy nh\u01b0\u1ee3c, m\u1ec7t m\u1ecfi, s\u1ed1t, r\u1ee5ng t\u00f3c, gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh, thi\u1ebfu m\u00e1u, h\u1ed9i ch\u1ee9ng cholinergic c\u1ea5p.<\/li>\n<li>Th\u01b0\u1eddng g\u1eb7p (&gt;1\/100 \u0111\u1ebfn &lt;1\/10): Gi\u1ea3m ti\u1ec3u c\u1ea7u, s\u1ed1t do gi\u1ea3m b\u1ea1ch c\u1ea7u, nhi\u1ec5m tr\u00f9ng, t\u0103ng bilirubin, t\u0103ng men gan, kh\u00f3 th\u1edf, ch\u00f3ng m\u1eb7t, m\u1ea5t ng\u1ee7.<\/li>\n<li>\u00cdt g\u1eb7p (&gt;1\/1000 \u0111\u1ebfn &lt;1\/100): T\u1eafc ru\u1ed9t, vi\u00eam \u0111\u1ea1i tr\u00e0ng gi\u1ea3 m\u1ea1c, b\u1ec7nh ph\u1ed5i k\u1ebd, suy th\u1eadn c\u1ea5p, ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn.<\/li>\n<li>Hi\u1ebfm g\u1eb7p (&lt;1\/1000): Bi\u1ebfn c\u1ed1 thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9 c\u01a1 tim, t\u0103ng huy\u1ebft \u00e1p, ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Ch\u1ea5t c\u1ea3m \u1ee9ng m\u1ea1nh CYP3A4 (v\u00ed d\u1ee5: Phenytoin, Carbamazepine, Rifampicin, St. John&#8217;s Wort): Gi\u1ea3m n\u1ed3ng \u0111\u1ed9 irinotecan v\u00e0 SN-38, c\u00f3 th\u1ec3 gi\u1ea3m hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb. C\u1ea7n tr\u00e1nh d\u00f9ng \u0111\u1ed3ng th\u1eddi.<\/li>\n<li>Ch\u1ea5t \u1ee9c ch\u1ebf m\u1ea1nh CYP3A4 v\u00e0\/ho\u1eb7c UGT1A1 (v\u00ed d\u1ee5: Ketoconazole, Itraconazole, c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf protease): T\u0103ng n\u1ed3ng \u0111\u1ed9 irinotecan v\u00e0\/ho\u1eb7c SN-38, t\u0103ng nguy c\u01a1 \u0111\u1ed9c t\u00ednh n\u1eb7ng. C\u1ea7n tr\u00e1nh d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u00e0 theo d\u00f5i ch\u1eb7t ch\u1ebd.<\/li>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf UGT1A1 kh\u00e1c (v\u00ed d\u1ee5: Regorafenib): T\u0103ng n\u1ed3ng \u0111\u1ed9 SN-38, t\u0103ng nguy c\u01a1 \u0111\u1ed9c t\u00ednh.<\/li>\n<li>C\u00e1c thu\u1ed1c g\u00e2y suy t\u1ee7y kh\u00e1c (v\u00ed d\u1ee5: h\u00f3a ch\u1ea5t tr\u1ecb ung th\u01b0 kh\u00e1c): T\u0103ng \u0111\u1ed9c t\u00ednh tr\u00ean t\u1ee7y x\u01b0\u01a1ng.<\/li>\n<li>Thu\u1ed1c ch\u1ee7ng ng\u1eeba s\u1ed1ng gi\u1ea3m \u0111\u1ed9c l\u1ef1c (v\u00ed d\u1ee5: v\u1eafc-xin s\u1edfi, quai b\u1ecb, rubella): Nguy c\u01a1 nhi\u1ec5m tr\u00f9ng lan t\u1ecfa. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh tuy\u1ec7t \u0111\u1ed1i.<\/li>\n<li>T\u01b0\u01a1ng t\u00e1c v\u1edbi th\u1ef1c ph\u1ea9m\/\u0111\u1ed3 u\u1ed1ng: B\u01b0\u1edfi v\u00e0 n\u01b0\u1edbc \u00e9p b\u01b0\u1edfi l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf m\u1ea1nh CYP3A4, c\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u0111\u00e1ng k\u1ec3 n\u1ed3ng \u0111\u1ed9 irinotecan v\u00e0 t\u0103ng \u0111\u1ed9c t\u00ednh. B\u1ec7nh nh\u00e2n n\u00ean tr\u00e1nh ho\u00e0n to\u00e0n b\u01b0\u1edfi v\u00e0 n\u01b0\u1edbc \u00e9p b\u01b0\u1edfi. Cam Seville v\u00e0 kh\u1ebf c\u0169ng n\u00ean tr\u00e1nh.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<ul>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai: Kh\u00f4ng d\u00f9ng thu\u1ed1c tr\u1eeb khi l\u1ee3i \u00edch r\u00f5 r\u00e0ng v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1 do \u0111\u1ed9c t\u00ednh tr\u00ean thai nhi.<\/li>\n<li>Ph\u1ee5 n\u1eef cho con b\u00fa: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh tuy\u1ec7t \u0111\u1ed1i cho con b\u00fa do nguy c\u01a1 g\u00e2y h\u1ea1i cho tr\u1ebb s\u01a1 sinh.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Irinotecan c\u00f3 th\u1ec3 g\u00e2y ch\u00f3ng m\u1eb7t, r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c (nh\u00ecn m\u1edd) ho\u1eb7c bu\u1ed3n ng\u1ee7 trong 24 gi\u1edd sau truy\u1ec1n. B\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u01b0\u1ee3c c\u1ea3nh b\u00e1o v\u00e0 kh\u00f4ng n\u00ean l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c n\u1ebfu g\u1eb7p c\u00e1c tri\u1ec7u ch\u1ee9ng n\u00e0y.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<ul>\n<li>Tri\u1ec7u ch\u1ee9ng: Qu\u00e1 li\u1ec1u (th\u01b0\u1eddng g\u1ea5p \u0111\u00f4i li\u1ec1u khuy\u1ebfn c\u00e1o) g\u00e2y tr\u1ea7m tr\u1ecdng c\u00e1c \u0111\u1ed9c t\u00ednh \u0111\u00e3 bi\u1ebft, \u0111\u1eb7c bi\u1ec7t l\u00e0 gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh n\u1eb7ng v\u00e0 ti\u00eau ch\u1ea3y n\u1eb7ng, c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn t\u1eed vong.<\/li>\n<li>X\u1eed tr\u00ed: Vi\u1ec7c x\u1eed tr\u00ed d\u1ef1a v\u00e0o \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 t\u1ed1i \u0111a.<\/li>\n<\/ul>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Kuldeep Rajpoot, Sunil K Jain. Irinotecan hydrochloride trihydrate loaded folic acid-tailored solid lipid nanoparticles for targeting colorectal cancer: development, characterization, and in vitro cytotoxicity study using HT-29 cells, truy c\u1eadp ng\u00e0y 27 th\u00e1ng 06 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31495238\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/31495238\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Irinotel 100mg\/5ml (Irinotecan) \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Fresenius Kabi Oncology Ltd, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 890114071323, thu\u1ed1c h\u00f3a tr\u1ecb li\u1ec7u \u0111i\u1ec1u tr\u1ecb ung th\u01b0.<\/p>\n","protected":false},"author":1,"featured_media":125145,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-125142","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/125142","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=125142"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/125145"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=125142"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=125142"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=125142"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}