{"id":125095,"date":"2025-06-27T16:50:15","date_gmt":"2025-06-27T09:50:15","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=125095"},"modified":"2025-07-24T11:47:51","modified_gmt":"2025-07-24T04:47:51","slug":"jardiance-duo-5mg-1000mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/jardiance-duo-5mg-1000mg\/","title":{"rendered":"Jardiance Duo 5mg\/1000mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Jardiance Duo 5mg\/1000mg c\u00f3 c\u01a1 s\u1edf s\u1ea3n xu\u1ea5t l\u00e0 Boehringer Ingelheim Pharma GmbH &amp; Co.KG, \u0111\u01b0\u1ee3c l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam v\u1edbi s\u1ed1 \u0111\u0103ng k\u00fd l\u00e0 VN3-188-19.<\/strong><\/p>\n<h2>Jardiance Duo 5mg\/1000mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean<strong> Jardiance Duo 5mg\/1000mg<\/strong>\u00a0ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li>Empagliflozin 5mg<\/li>\n<li>Metformin Hydrochloride 1000mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf : Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN3-188-19<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: \u0110\u1ee9c<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Jardiance Duo 5mg\/1000mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Empagliflozin l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf ch\u1ecdn l\u1ecdc v\u00e0 m\u1ea1nh \u0111\u1ed3ng v\u1eadn chuy\u1ec3n natri\u2013glucose type 2 (SGLT2), ch\u1ee7 y\u1ebfu bi\u1ec3u hi\u1ec7n \u1edf \u0111o\u1ea1n \u0111\u1ea7u \u1ed1ng l\u01b0\u1ee3n g\u1ea7n c\u1ee7a nephron. SGLT2 ch\u1ecbu tr\u00e1ch nhi\u1ec7m cho kho\u1ea3ng 90 % l\u01b0\u1ee3ng glucose l\u1ecdc qua c\u1ea7u th\u1eadn \u0111\u01b0\u1ee3c t\u00e1i h\u1ea5p thu; khi b\u1ecb \u1ee9c ch\u1ebf, qu\u00e1 tr\u00ecnh t\u00e1i h\u1ea5p thu glucose gi\u1ea3m, d\u1eabn \u0111\u1ebfn t\u0103ng th\u1ea3i glucose qua n\u01b0\u1edbc ti\u1ec3u (glucosuria) v\u00e0 h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2, c\u01a1 ch\u1ebf ho\u00e0n to\u00e0n \u0111\u1ed9c l\u1eadp v\u1edbi insulin .<\/p>\n<p>Metformin ch\u1ee7 y\u1ebfu ho\u1ea1t h\u00f3a AMP-activated protein kinase (AMPK), qua \u0111\u00f3 th\u1ef1c hi\u1ec7n c\u00e1c t\u00e1c \u0111\u1ed9ng sau: \u1edf gan, AMPK \u1ee9c ch\u1ebf gluconeogenesis v\u00e0 t\u1ed5ng h\u1ee3p acid b\u00e9o, l\u00e0m gi\u1ea3m s\u1ea3n xu\u1ea5t glucose n\u1ed9i sinh; t\u1ea1i c\u01a1 x\u01b0\u01a1ng, AMPK th\u00fac \u0111\u1ea9y chuy\u1ec3n v\u1ecb GLUT4 l\u00ean m\u00e0ng t\u1ebf b\u00e0o, t\u0103ng h\u1ea5p thu glucose ngo\u1ea1i vi; \u0111\u1ed3ng th\u1eddi, metformin c\u00f2n \u1ee9c ch\u1ebf t\u00edn hi\u1ec7u glucagon b\u1eb1ng c\u00e1ch ng\u0103n adenylate cyclase, g\u00f3p ph\u1ea7n gi\u1ea3m t\u1ea1o cAMP v\u00e0 gluconeogenesis. Ngo\u00e0i ra, metformin c\u1ea3i thi\u1ec7n qu\u00e1 tr\u00ecnh t\u1ef1 th\u1ef1c (autophagy) \u1edf t\u1ebf b\u00e0o \u03b2 tuy\u1ebfn t\u1ee5y, gi\u00fap gi\u1ea3m stress n\u1ed9i b\u00e0o trong \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng .<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<h4>H\u1ea5p thu<\/h4>\n<p>Empagliflozin c\u00f3 sinh kh\u1ea3 d\u1ee5ng kho\u1ea3ng 78%\u201390% v\u00e0 kh\u00f4ng ch\u1ecbu \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 c\u1ee7a th\u1ee9c \u0103n l\u00ean t\u1ed1c \u0111\u1ed9 h\u1ea5p thu. Trong khi \u0111\u00f3, metformin khi d\u00f9ng c\u00f9ng b\u1eefa \u0103n nhi\u1ec1u ch\u1ea5t b\u00e9o c\u00f3 th\u1ec3 gi\u1ea3m nh\u1eb9 sinh kh\u1ea3 d\u1ee5ng v\u00e0 t\u1ed1c \u0111\u1ed9 \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh c\u0169ng ch\u1eadm h\u01a1n \u0111\u00f4i ch\u00fat.<\/p>\n<h4>Ph\u00e2n b\u1ed1<\/h4>\n<p>Empagliflozin c\u00f3 th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 \u1edf tr\u1ea1ng th\u00e1i c\u00e2n b\u1eb1ng kho\u1ea3ng 73,8L, ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i v\u00e0o m\u00f4 ni\u1ec7u ti\u1ebft v\u00e0 ngo\u1ea1i vi. Metformin c\u00f3 t\u1ef7 l\u1ec7 g\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng r\u1ea5t th\u1ea5p, th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 l\u1edbn.<\/p>\n<h4>Chuy\u1ec3n h\u00f3a<\/h4>\n<p>Empagliflozin h\u1ea7u nh\u01b0 kh\u00f4ng b\u1ecb chuy\u1ec3n h\u00f3a qua h\u1ec7 th\u1ed1ng enzym CYP450, c\u00e1c qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a ph\u1ee5 t\u1ea1o ra c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00f4ng ho\u1ea1t t\u00ednh v\u1edbi t\u1ef7 l\u1ec7 r\u1ea5t nh\u1ecf, kh\u00f4ng c\u00f3 vai tr\u00f2 l\u00e2m s\u00e0ng \u0111\u00e1ng k\u1ec3. Metformin kh\u00f4ng ch\u1ecbu s\u1ef1 chuy\u1ec3n h\u00f3a \u1edf gan, to\u00e0n b\u1ed9 l\u01b0\u1ee3ng thu\u1ed1c h\u1ea5p thu \u0111\u01b0\u1ee3c gi\u1eef nguy\u00ean cho \u0111\u1ebfn khi th\u1ea3i tr\u1eeb.<\/p>\n<h4>Th\u1ea3i tr\u1eeb<\/h4>\n<p>Thu\u1ed1c \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft ch\u1ee7 y\u1ebfu qua th\u1eadn v\u00e0 m\u1eadt.<\/p>\n<h2>Jardiance Duo 5mg\/1000mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p><strong>Jardiance Duo 5mg\/1000mg Empagliflozin <\/strong>\u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 li\u1ec7u ph\u00e1p b\u1ed5 tr\u1ee3 ch\u1ebf \u0111\u1ed9 \u0103n v\u00e0 v\u1eadn \u0111\u1ed9ng trong \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2 \u1edf c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n<ul>\n<li>B\u1ec7nh nh\u00e2n kh\u00f4ng \u0111\u1ea1t ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft t\u1ed1i \u01b0u khi \u0111i\u1ec1u tr\u1ecb \u0111\u01a1n \u0111\u1ed9c metformin ho\u1eb7c empagliflozin.<\/li>\n<li>B\u1ec7nh nh\u00e2n kh\u00f4ng ki\u1ec3m so\u00e1t t\u1ed1t \u0111\u01b0\u1eddng huy\u1ebft d\u00f9 \u0111\u00e3 k\u1ebft h\u1ee3p metformin ho\u1eb7c empagliflozin v\u1edbi c\u00e1c thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft kh\u00e1c (k\u1ec3 c\u1ea3 insulin).<\/li>\n<li>B\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng ri\u00eang r\u1ebd empagliflozin v\u00e0 metformin c\u00f3 nhu c\u1ea7u chuy\u1ec3n sang vi\u00ean ph\u1ed1i h\u1ee3p c\u1ed1 \u0111\u1ecbnh \u0111\u1ec3 t\u0103ng t\u00ednh ti\u1ec7n l\u1ee3i v\u00e0 kh\u1ea3 n\u0103ng tu\u00e2n th\u1ee7 \u0111i\u1ec1u tr\u1ecb<\/li>\n<li>\n<figure id=\"attachment_125099\" aria-describedby=\"caption-attachment-125099\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-125099\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/jardiance-duo-5mg-1000mg-dieu-tri-dai-thao-duong-type-2.jpg\" alt=\"Jardiance Duo 5mg\/1000mg \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/jardiance-duo-5mg-1000mg-dieu-tri-dai-thao-duong-type-2.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/jardiance-duo-5mg-1000mg-dieu-tri-dai-thao-duong-type-2-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/jardiance-duo-5mg-1000mg-dieu-tri-dai-thao-duong-type-2-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/jardiance-duo-5mg-1000mg-dieu-tri-dai-thao-duong-type-2-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-125099\" class=\"wp-caption-text\">Jardiance Duo 5mg\/1000mg \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2<\/figcaption><\/figure><\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Jardiance Duo 5mg\/1000mg<\/h2>\n<p>\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u kh\u1edfi \u0111\u1ea7u theo ph\u00e1c \u0111\u1ed3 hi\u1ec7n t\u1ea1i:<\/p>\n<ul>\n<li>Tr\u01b0\u1edbc \u0111\u00e2y ch\u1ec9 d\u00f9ng Metformin: t\u00ednh li\u1ec1u t\u01b0\u01a1ng \u0111\u01b0\u01a1ng li\u1ec1u Metformin \u0111ang d\u00f9ng (Empagliflozin kh\u1edfi \u0111\u1ea7u 5mg)<\/li>\n<li>Tr\u01b0\u1edbc \u0111\u00e2y ch\u1ec9 d\u00f9ng Empagliflozin: t\u00ednh li\u1ec1u t\u01b0\u01a1ng \u0111\u01b0\u01a1ng li\u1ec1u Empagliflozin \u0111ang d\u00f9ng (Metformin 500mg)<\/li>\n<li>Tr\u01b0\u1edbc \u0111\u00e2y ph\u1ed1i h\u1ee3p Empagliflozin + Metformin: t\u00ednh li\u1ec1u sao cho t\u1ed5ng li\u1ec1u 2 thu\u1ed1c t\u01b0\u01a1ng \u0111\u01b0\u01a1ng ph\u00e1c \u0111\u1ed3 c\u0169<\/li>\n<\/ul>\n<p>Gi\u1edbi h\u1ea1n li\u1ec1u t\u1ed1i \u0111a\/ng\u00e0y: Empagliflozin 25mg v\u00e0 Metformin 2000mg<\/p>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Jardiance Duo 5mg\/1000mg<\/h2>\n<p>U\u1ed1ng nguy\u00ean vi\u00ean thu\u1ed1c c\u00f9ng n\u01b0\u1edbc, kh\u00f4ng nhai, nghi\u1ec1n hay b\u1ebb vi\u00ean thu\u1ed1c. D\u00f9ng c\u00f9ng b\u1eefa \u0103n s\u00e1ng v\u00e0 t\u1ed1i (2 l\u1ea7n\/ng\u00e0y).<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Jardiance Duo 5mg\/1000mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Kh\u00f4ng d\u00f9ng Jardiance Duo 5mg\/1000mg cho ng\u01b0\u1eddi c\u00f3 m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>Nhi\u1ec5m toan chuy\u1ec3n h\u00f3a c\u1ea5p ho\u1eb7c m\u00e3n t\u00ednh, bao g\u1ed3m c\u1ea3 nhi\u1ec5m toan ceton do \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng.<\/li>\n<li>Suy th\u1eadn m\u1ee9c \u0111\u1ed9 trung b\u00ecnh \u0111\u1ebfn n\u1eb7ng (eGFR &lt; 45 mL\/ph\u00fat\/1,73 m\u00b2).<\/li>\n<li>Suy gan n\u1eb7ng, ng\u1ed9 \u0111\u1ed9c r\u01b0\u1ee3u c\u1ea5p t\u00ednh ho\u1eb7c nghi\u1ec7n r\u01b0\u1ee3u.<\/li>\n<li>R\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng th\u1eadn k\u00e8m m\u1ea5t n\u01b0\u1edbc n\u1eb7ng, s\u1ed1c, nhi\u1ec5m tr\u00f9ng n\u1eb7ng ho\u1eb7c \u0111ang s\u1eed d\u1ee5ng thu\u1ed1c c\u1ea3n quang ch\u1ee9a i\u1ed1t \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch.<\/li>\n<li>Suy tim m\u1ea5t b\u00f9, nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p ho\u1eb7c suy h\u00f4 h\u1ea5p do gi\u1ea3m cung c\u1ea5p oxy m\u00f4.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Jardiance Duo 5mg\/1000mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Ki\u00eang r\u01b0\u1ee3u bia tuy\u1ec7t \u0111\u1ed1i : R\u01b0\u1ee3u l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m toan lactic (MALA) do \u1ee9c ch\u1ebf chuy\u1ec3n h\u00f3a lactate \u1edf gan v\u00e0 l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng lo\u1ea1i b\u1ecf lactate c\u1ee7a th\u1eadn. M\u1eb7c d\u00f9 MALA r\u1ea5t hi\u1ebfm (\uff1c10 tr\u01b0\u1eddng h\u1ee3p\/100.000 n\u0103m b\u1ec7nh nh\u00e2n), nh\u01b0ng khi k\u1ebft h\u1ee3p v\u1edbi u\u1ed1ng nhi\u1ec1u r\u01b0\u1ee3u, nguy c\u01a1 n\u00e0y t\u0103ng \u0111\u00e1ng k\u1ec3, t\u1eed vong l\u00ean \u0111\u1ebfn 30\u201350% trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p b\u00e1o c\u00e1o.<\/p>\n<p>Theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn \u0111\u1ecbnh k\u1ef3 : Metformin \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i ch\u1ee7 y\u1ebfu qua th\u1eadn; do \u0111\u00f3, c\u1ea7n \u0111\u00e1nh gi\u00e1 eGFR tr\u01b0\u1edbc khi kh\u1edfi tr\u1ecb v\u00e0 \u0111\u1ecbnh k\u1ef3 (v\u00ed d\u1ee5: 6\u201312 th\u00e1ng cho eGFR \u226560 mL\/ph\u00fat, 3\u20136 th\u00e1ng cho eGFR 45\u201359 mL\/ph\u00fat, 3 th\u00e1ng cho eGFR 30\u201344 mL\/ph\u00fat) \u0111\u1ec3 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u ho\u1eb7c ng\u01b0ng thu\u1ed1c khi eGFR &lt;30 mL\/ph\u00fat nh\u1eb1m gi\u1ea3m nguy c\u01a1 t\u00edch l\u0169y thu\u1ed1c v\u00e0 toan lactic.<\/p>\n<p>Duy tr\u00ec ch\u1ebf \u0111\u1ed9 dinh d\u01b0\u1ee1ng h\u1ee3p l\u00fd<\/p>\n<p>Tri\u1ec7u ch\u1ee9ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft (\u0111\u00f3i, v\u00e3 m\u1ed3 h\u00f4i, tim \u0111\u1eadp nhanh, hoa m\u1eaft) c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n tho\u00e1ng qua v\u00e0 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng t\u1eadp trung. B\u1ec7nh nh\u00e2n n\u00ean t\u1ef1 ki\u1ec3m tra d\u1ea5u hi\u1ec7u h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft tr\u01b0\u1edbc khi l\u00e1i xe.<\/p>\n<p>Thu\u1ed1c c\u1ea3n quang c\u00f3 th\u1ec3 g\u00e2y suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn c\u1ea5p t\u00ednh, l\u00e0m t\u0103ng nguy c\u01a1 MALA. Theo H\u1ed9i X quang Ch\u00e2u \u00c2u, n\u00ean ng\u01b0ng metformin \u00edt nh\u1ea5t 48 gi\u1edd tr\u01b0\u1edbc khi ch\u1ee5p CT ho\u1eb7c X-quang c\u1ea3n quang v\u00e0 ch\u1ec9 t\u00e1i s\u1eed d\u1ee5ng sau khi x\u00e1c nh\u1eadn eGFR \u1ed5n \u0111\u1ecbnh (&lt;25% t\u0103ng creatinin so v\u1edbi ban \u0111\u1ea7u).<\/p>\n<p>Trong c\u00e1c t\u00ecnh hu\u1ed1ng c\u1ea5p c\u1ee9u nh\u01b0 m\u1ea5t n\u01b0\u1edbc c\u1ea5p (ti\u00eau ch\u1ea3y, n\u00f4n \u00f3i, m\u1ea5t mu\u1ed1i); s\u1ed1c, gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n r\u00f5 r\u1ec7t; nhi\u1ec5m tr\u00f9ng n\u1eb7ng ho\u1eb7c c\u00f3 bi\u1ebfn ch\u1ee9ng (v\u00ed d\u1ee5 vi\u00eam \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u n\u1eb7ng); n\u00ean ng\u01b0ng thu\u1ed1c ngay.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>Hay g\u1eb7p : nhi\u1ec5m tr\u00f9ng v\u00f9ng sinh d\u1ee5c (n\u1ea5m men, vi\u00eam \u00e2m \u0111\u1ea1o, balanitis).<\/li>\n<li>Th\u01b0\u1eddng g\u1eb7p : nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u, h\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf (cho\u00e1ng khi \u0111\u1ee9ng l\u00ean).<\/li>\n<li>\u00cdt g\u1eb7p : c\u1ea3m gi\u00e1c kh\u00f4 mi\u1ec7ng, kh\u00e1t nhi\u1ec1u.<\/li>\n<li>Hi\u1ebfm g\u1eb7p : nhi\u1ec5m toan ceton do \u1ee9c ch\u1ebf SGLT2, suy th\u1eadn c\u1ea5p.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi thu\u1ed1c l\u1ee3i ti\u1ec3u quai ho\u1eb7c thiazide: khi k\u1ebft h\u1ee3p c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 t\u1ee5t huy\u1ebft \u00e1p t\u01b0 th\u1ebf, g\u00e2y cho\u00e1ng ho\u1eb7c ng\u1ea5t.<\/p>\n<p>C\u1ea3nh b\u00e1o v\u00e0 theo d\u00f5i khi d\u00f9ng c\u00f9ng<\/p>\n<ul>\n<li>Sulfonylurea, insulin: d\u00f9ng chung c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft nghi\u00eam tr\u1ecdng, c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u v\u00e0 theo d\u00f5i \u0111\u01b0\u1eddng huy\u1ebft ch\u1eb7t ch\u1ebd.<\/li>\n<li>Cimetidine: l\u00e0m gi\u1ea3m t\u1ed1c \u0111\u1ed9 th\u1ea3i tr\u1eeb metformin qua th\u1eadn, c\u1ea7n ki\u1ec3m tra ch\u1ee9c n\u0103ng th\u1eadn th\u01b0\u1eddng xuy\u00ean v\u00e0 xem x\u00e9t \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u.<\/li>\n<li>Zonisamide, acetazolamide, topiramate: \u0111\u1ed3ng s\u1eed d\u1ee5ng c\u00f3 kh\u1ea3 n\u0103ng gia t\u0103ng t\u00ecnh tr\u1ea1ng toan chuy\u1ec3n h\u00f3a, n\u00ean c\u00e2n nh\u1eafc l\u1ee3i \u00edch \u2013 nguy c\u01a1 v\u00e0 gi\u00e1m s\u00e1t c\u00e2n b\u1eb1ng acid\u2013base.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ch\u1ec9 d\u00f9ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa khi l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>B\u00e1o ngay v\u1edbi b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng k\u1ecbp th\u1eddi.<\/p>\n<h2>Jardiance Duo 5mg\/1000mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Jardiance Duo 5mg\/1000mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng v\u1edbi nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/jardiance-25mg\/\">Jardiance<\/a> \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tu\u00fdp 2 \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh nh\u1eb1m c\u1ea3i thi\u1ec7n t\u00ecnh tr\u1ea1ng \u0111\u01b0\u1eddng huy\u1ebft khi ch\u1ebf \u0111\u1ed9 \u0103n v\u00e0 t\u1eadp luy\u1ec7n th\u1ec3 d\u1ee5c kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng tr\u00ean nh\u1eefng b\u1ec7nh nh\u00e2n kh\u00f4ng th\u00edch h\u1ee3p d\u00f9ng Metformin.<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/nady-empag-10\/\">Nady-Empag 10<\/a> ch\u1ee9a Empagliflozin h\u00e0m l\u01b0\u1ee3ng 10mg, \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft cho b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng t\u00fdp 2 khi ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng v\u00e0 luy\u1ec7n t\u1eadp kh\u00f4ng \u0111\u1ee7 hi\u1ec7u qu\u1ea3.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>1. H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng \u0111\u01b0\u1ee3c C\u1ee5c qu\u1ea3n l\u00fd ph\u00ea duy\u1ec7t. Xem ngay <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/jardiance-duo-5mg-1000mg-huong-dan-su-dung.pdf\">T\u1ea0I \u0110\u00c2Y<\/a>.<\/p>\n<p>2. Hideaki Kaneto, Tomohiko Kimura, Atsushi Obata, Masashi Shimoda, Kohei Kaku (2021), Multifaceted Mechanisms of Action of Metformin Which Have Been Unraveled One after Another in the Long History. Truy c\u1eadp ng\u00e0y 27\/06\/2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33807522\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33807522\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Jardiance Duo 5mg\/1000mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft \u1edf b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng type 2 khi \u0111i\u1ec1u tr\u1ecb \u0111\u01a1n l\u1ebb b\u1eb1ng metformin ho\u1eb7c empagliflozin kh\u00f4ng \u0111\u1ea1t hi\u1ec7u qu\u1ea3.<\/p>\n","protected":false},"author":1,"featured_media":125100,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-125095","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/125095","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=125095"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/125100"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=125095"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=125095"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=125095"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}