{"id":125051,"date":"2025-06-27T15:36:48","date_gmt":"2025-06-27T08:36:48","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=125051"},"modified":"2025-07-24T11:47:52","modified_gmt":"2025-07-24T04:47:52","slug":"jardiance-duo-12-5mg-850mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/jardiance-duo-12-5mg-850mg\/","title":{"rendered":"Jardiance Duo 12.5mg\/850mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Jardiance Duo 12.5mg\/850mg c\u00f3 c\u01a1 s\u1edf s\u1ea3n xu\u1ea5t l\u00e0 Boehringer Ingelheim Pharma GmbH &amp; Co.KG, \u0111\u01b0\u1ee3c l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam v\u1edbi s\u1ed1 \u0111\u0103ng k\u00fd l\u00e0 VN3-186-19.<\/strong><\/p>\n<h2>Jardiance Duo 12.5mg\/850mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean<strong> Jardiance Duo 12.5mg\/850mg<\/strong>\u00a0ch\u1ee9a th\u00e0nh ph\u1ea7n:<\/p>\n<ul>\n<li>Empagliflozin 12,5mg<\/li>\n<li>Metformin Hydrochloride 850mg<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf : Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN3-186-19<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: \u0110\u1ee9c<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Jardiance Duo 12.5mg\/850mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Empagliflozin l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf \u0111\u1ed3ng v\u1eadn chuy\u1ec3n glucose natri 2 m\u1ea1nh. Glucose natri 2 \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y trong \u1ed1ng l\u01b0\u1ee3n g\u1ea7n c\u1ee7a nephron, ch\u1ecbu tr\u00e1ch nhi\u1ec7m t\u00e1i h\u1ea5p thu kho\u1ea3ng 90% glucose \u0111\u01b0\u1ee3c l\u1ecdc qua th\u1eadn. B\u1eb1ng c\u00e1ch ch\u1eb7n glucose natri 2, empagliflozin l\u00e0m gi\u1ea3m t\u00e1i h\u1ea5p thu glucose \u1edf th\u1eadn, d\u1eabn \u0111\u1ebfn b\u00e0i ti\u1ebft glucose v\u00e0o n\u01b0\u1edbc ti\u1ec3u, do \u0111\u00f3 l\u00e0m gi\u1ea3m t\u00ecnh tr\u1ea1ng t\u0103ng \u0111\u01b0\u1eddng huy\u1ebft \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2.<\/p>\n<p>Metformin l\u00e0m t\u0103ng \u0111\u1ed9 nh\u1ea1y insulin. Metformin ch\u1ee7 y\u1ebfu k\u00edch ho\u1ea1t protein kinase ho\u1ea1t h\u00f3a adenosine monophosphate (AMPK) trong gan d\u1eabn \u0111\u1ebfn \u1ee9c ch\u1ebf t\u1ed5ng h\u1ee3p axit b\u00e9o v\u00e0 t\u00e2n t\u1ea1o glucose. Metformin c\u0169ng k\u00edch ho\u1ea1t AMPK trong c\u01a1 x\u01b0\u01a1ng, l\u00e0m t\u0103ng s\u1ef1 chuy\u1ec3n v\u1ecb c\u1ee7a ch\u1ea5t v\u1eadn chuy\u1ec3n glucose 4 \u0111\u1ebfn m\u00e0ng t\u1ebf b\u00e0o v\u00e0 do \u0111\u00f3 l\u00e0m t\u0103ng h\u1ea5p thu glucose. H\u01a1n n\u1eefa, metformin \u1ee9c ch\u1ebf t\u00edn hi\u1ec7u glucagon trong gan b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf adenylate cyclase d\u1eabn \u0111\u1ebfn \u1ee9c ch\u1ebf t\u00e2n t\u1ea1o glucose. Ngo\u00e0i ra, metformin l\u00e0m gi\u1ea3m t\u00ecnh tr\u1ea1ng suy t\u1ef1 th\u1ef1c \u0111\u01b0\u1ee3c quan s\u00e1t th\u1ea5y \u1edf c\u00e1c t\u1ebf b\u00e0o \u03b2 tuy\u1ebfn t\u1ee5y trong t\u00ecnh tr\u1ea1ng b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<h4>H\u1ea5p thu<\/h4>\n<p>Empagliflozin \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh sau 1,5\u20132,1 gi\u1edd, Metformin c\u00f3 sinh kh\u1ea3 d\u1ee5ng 50\u201360% trong tr\u1ea1ng th\u00e1i nh\u1ecbn \u0111\u00f3i.<\/p>\n<h4>Ph\u00e2n b\u1ed1<\/h4>\n<p>Metformin c\u00f3 th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 trung b\u00ecnh 654 \u00b1 358L, g\u1eafn r\u1ea5t \u00edt v\u00e0o protein huy\u1ebft t\u01b0\u01a1ng; Empagliflozin ph\u00e2n b\u1ed1 r\u1ed9ng kh\u1eafp m\u00f4 ni\u1ec7u ti\u1ebft v\u00e0 m\u00f4 ngo\u1ea1i vi, kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o th\u1ee9c \u0103n.<\/p>\n<h4>Chuy\u1ec3n h\u00f3a<\/h4>\n<p>Empagliflozin h\u1ea7u nh\u01b0 kh\u00f4ng chuy\u1ec3n h\u00f3a qua CYP450, c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a r\u1ea5t nh\u1eb9 v\u00e0 kh\u00f4ng v\u01b0\u1ee3t tr\u1ed9i v\u1ec1 m\u1eb7t l\u01b0\u1ee3ng; Metformin kh\u00f4ng chuy\u1ec3n h\u00f3a \u1edf gan<\/p>\n<h4>Th\u1ea3i tr\u1eeb<\/h4>\n<p>Sau khi d\u00f9ng Empagliflozin, kho\u1ea3ng 41,2% li\u1ec1u \u0111\u01b0\u1ee3c th\u1ea3i ra ph\u00e2n v\u00e0 54,4% qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i, th\u1eddi gian b\u00e1n th\u1ea3i cu\u1ed1i kho\u1ea3ng 12,4 gi\u1edd. Metformin \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb kh\u00f4ng chuy\u1ec3n h\u00f3a qua th\u1eadn (90% li\u1ec1u h\u1ea5p thu), th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 14 gi\u1edd.<\/p>\n<h2>Jardiance Duo 12.5mg\/850mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p><strong>Jardiance Duo 12.5mg\/850mg Empagliflozin<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong\u00a0ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2 trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n<ul>\n<li>Khi \u0111i\u1ec1u tr\u1ecb \u0111\u01a1n l\u1ebb b\u1eb1ng metformin ho\u1eb7c empagliflozin kh\u00f4ng \u0111\u1ea1t hi\u1ec7u qu\u1ea3 mong mu\u1ed1n.<\/li>\n<li>Khi b\u1ec7nh nh\u00e2n kh\u00f4ng ki\u1ec3m so\u00e1t t\u1ed1t \u0111\u01b0\u1eddng huy\u1ebft d\u00f9 \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng metformin ho\u1eb7c empagliflozin k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft kh\u00e1c, k\u1ec3 c\u1ea3 insulin.<\/li>\n<li>Khi b\u1ec7nh nh\u00e2n \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb ph\u1ed1i h\u1ee3p empagliflozin v\u00e0 metformin \u1edf d\u1ea1ng vi\u00ean ri\u00eang bi\u1ec7t v\u00e0 c\u00f3 nhu c\u1ea7u chuy\u1ec3n sang d\u1ea1ng ph\u1ed1i h\u1ee3p c\u1ed1 \u0111\u1ecbnh \u0111\u1ec3 c\u1ea3i thi\u1ec7n tu\u00e2n th\u1ee7 \u0111i\u1ec1u tr\u1ecb.<\/li>\n<\/ul>\n<p>\u0110i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi b\u1eb1ng empagliflozin v\u00e0 metformin \u0111\u00e3 cho th\u1ea5y hi\u1ec7u qu\u1ea3 c\u1ea3i thi\u1ec7n ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft r\u00f5 r\u1ec7t.<\/p>\n<p>Empagliflozin c\u00f2n \u0111\u01b0\u1ee3c ch\u1ee9ng minh c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m gi\u1ea3m nguy c\u01a1 t\u1eed vong \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2 c\u00f3 b\u1ec7nh n\u1ec1n tim m\u1ea1ch. Tuy nhi\u00ean, hi\u1ec7u qu\u1ea3 gi\u1ea3m nguy c\u01a1 tim m\u1ea1ch n\u00e0y ch\u01b0a \u0111\u01b0\u1ee3c x\u00e1c l\u1eadp r\u00f5 r\u00e0ng \u0111\u1ed1i v\u1edbi d\u1ea1ng ph\u1ed1i h\u1ee3p c\u1ed1 \u0111\u1ecbnh nh\u01b0 Jardiance Duo 12,5mg\/850mg.<\/p>\n<figure id=\"attachment_125053\" aria-describedby=\"caption-attachment-125053\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-125053\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/jardiance-duo-12-5mg-850mg-dieu-tri-dai-thao-duong-type-2.jpg\" alt=\"Jardiance Duo 12.5mg\/850mg \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/jardiance-duo-12-5mg-850mg-dieu-tri-dai-thao-duong-type-2.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/jardiance-duo-12-5mg-850mg-dieu-tri-dai-thao-duong-type-2-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/jardiance-duo-12-5mg-850mg-dieu-tri-dai-thao-duong-type-2-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/jardiance-duo-12-5mg-850mg-dieu-tri-dai-thao-duong-type-2-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-125053\" class=\"wp-caption-text\">Jardiance Duo 12.5mg\/850mg \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng type 2<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Jardiance Duo 12.5mg\/850mg<\/h2>\n<p>Li\u1ec1u d\u00f9ng chung: 1 vi\u00ean\/l\u1ea7n, 2 l\u1ea7n\/ng\u00e0y (s\u00e1ng, t\u1ed1i c\u00f9ng b\u1eefa \u0103n)<\/p>\n<p>\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u kh\u1edfi \u0111\u1ea7u theo ph\u00e1c \u0111\u1ed3 hi\u1ec7n t\u1ea1i:<\/p>\n<ul>\n<li>Tr\u01b0\u1edbc \u0111\u00e2y ch\u1ec9 d\u00f9ng Metformin: li\u1ec1u Jardiance Duo 12.5mg\/850mg t\u01b0\u01a1ng \u1ee9ng li\u1ec1u Metformin \u0111ang d\u00f9ng (Empagliflozin kh\u1edfi \u0111\u1ea7u 5mg).<\/li>\n<li>Tr\u01b0\u1edbc \u0111\u00e2y ch\u1ec9 d\u00f9ng Empagliflozin: li\u1ec1u Jardiance Duo 12.5\/850 t\u01b0\u01a1ng \u1ee9ng li\u1ec1u Empagliflozin \u0111ang d\u00f9ng (Metformin 500mg)<\/li>\n<li>Tr\u01b0\u1edbc \u0111\u00e2y ph\u1ed1i h\u1ee3p Empagliflozin + Metformin: ch\u1ecdn li\u1ec1u Jardiance Duo 12.5mg\/850mg sao cho t\u1ed5ng li\u1ec1u 2 thu\u1ed1c t\u01b0\u01a1ng \u0111\u01b0\u01a1ng ph\u00e1c \u0111\u1ed3 c\u0169.<\/li>\n<\/ul>\n<p>Li\u1ec1u t\u1ed1i \u0111a\/ng\u00e0y: Empagliflozin 25mg; Metformin 2000mg.<\/p>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Jardiance Duo 12.5mg\/850mg<\/h2>\n<p>U\u1ed1ng nguy\u00ean vi\u00ean thu\u1ed1c c\u00f9ng n\u01b0\u1edbc, kh\u00f4ng nhai, nghi\u1ec1n hay b\u1ebb vi\u00ean thu\u1ed1c. D\u00f9ng c\u00f9ng b\u1eefa \u0103n.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Jardiance Duo 12.5mg\/850mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Kh\u00f4ng d\u00f9ng Jardiance Duo 12.5mg\/850mg cho ng\u01b0\u1eddi c\u00f3 m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>Ng\u01b0\u1eddi b\u1ecb nhi\u1ec5m toan chuy\u1ec3n h\u00f3a c\u1ea5p ho\u1eb7c m\u00e3n t\u00ednh, k\u1ec3 c\u1ea3 nhi\u1ec5m toan ceton do \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng.<\/li>\n<li>B\u1ec7nh nh\u00e2n suy th\u1eadn v\u1eeba v\u00e0 n\u1eb7ng c\u00f3 ch\u1ec9 s\u1ed1 eGFR nh\u1ecf h\u01a1n 45m\/ph\u00fat\/1,73m\u00b2.<\/li>\n<li>B\u1ec7nh nh\u00e2n suy gan, ng\u1ed9 \u0111\u1ed9c r\u01b0\u1ee3u c\u1ea5p t\u00ednh ho\u1eb7c nghi\u1ec7n r\u01b0\u1ee3u.<\/li>\n<li>Ng\u01b0\u1eddi b\u1ecb r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng th\u1eadn g\u00e2y m\u1ea5t n\u01b0\u1edbc, s\u1ed1c, nhi\u1ec5m tr\u00f9ng n\u1eb7ng ho\u1eb7c d\u00f9ng thu\u1ed1c c\u1ea3n quang c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n iot d\u1ea1ng ti\u00eam m\u1ea1ch.<\/li>\n<li>Ng\u01b0\u1eddi b\u1ec7nh b\u1ecb suy tim m\u1ea5t b\u00f9, nh\u1ed3i m\u00e1u c\u01a1 tim, suy h\u00f4 h\u1ea5p do m\u00f4 kh\u00f4ng \u0111\u01b0\u1ee3c cung c\u1ea5p \u0111\u1ee7 oxy.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Jardiance Duo 12.5mg\/850mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng s\u1eed d\u1ee5ng r\u01b0\u1ee3u bia trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, v\u00ec c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m toan lactic.<\/p>\n<p>Metformin \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i ch\u1ee7 y\u1ebfu qua th\u1eadn, do \u0111\u00f3 c\u1ea7n theo d\u00f5i ch\u1ee9c n\u0103ng th\u1eadn \u0111\u1ecbnh k\u1ef3, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi cao tu\u1ed5i.<\/p>\n<p>K\u1ebft h\u1ee3p thu\u1ed1c v\u1edbi ch\u1ebf \u0111\u1ed9 \u0103n c\u00e2n \u0111\u1ed1i: \u0111\u1ee7 \u0111\u1ea1m, tinh b\u1ed9t, vitamin v\u00e0 kho\u00e1ng ch\u1ea5t; chia nh\u1ecf b\u1eefa \u0103n; h\u1ea1n ch\u1ebf th\u1ef1c ph\u1ea9m ch\u1ee9a nhi\u1ec1u \u0111\u01b0\u1eddng (b\u00e1nh k\u1eb9o, m\u1ee9t, n\u01b0\u1edbc ng\u1ecdt).<\/p>\n<p>Tr\u01b0\u1edbc khi l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c, b\u1ec7nh nh\u00e2n c\u1ea7n \u0111\u00e1nh gi\u00e1 t\u00ecnh tr\u1ea1ng s\u1ee9c kh\u1ecfe \u0111\u1ec3 tr\u00e1nh c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 g\u00e2y nguy hi\u1ec3m.<\/p>\n<p>Ng\u01b0ng d\u00f9ng Jardiance Duo 12,5mg\/850mg \u00edt nh\u1ea5t 48 gi\u1edd tr\u01b0\u1edbc khi ch\u1ee5p X-quang c\u00f3 ti\u00eam ho\u1eb7c u\u1ed1ng ch\u1ea5t c\u1ea3n quang ch\u1ee9a iod.<\/p>\n<p>Th\u1eadn tr\u1ecdng ho\u1eb7c t\u1ea1m d\u1eebng \u0111i\u1ec1u tr\u1ecb \u1edf nh\u1eefng tr\u01b0\u1eddng h\u1ee3p:<\/p>\n<ul>\n<li>C\u00f3 nguy c\u01a1 gi\u1ea3m th\u1ec3 t\u00edch tu\u1ea7n ho\u00e0n (m\u1ea5t n\u01b0\u1edbc, ti\u00eau ch\u1ea3y, n\u00f4n \u00f3i).<\/li>\n<li>Nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u n\u1eb7ng ho\u1eb7c c\u00f3 bi\u1ebfn ch\u1ee9ng.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>Hay g\u1eb7p : nhi\u1ec5m tr\u00f9ng v\u00f9ng sinh d\u1ee5c.<\/li>\n<li>Th\u01b0\u1eddng g\u1eb7p : nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u, h\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf.<\/li>\n<li>\u00cdt g\u1eb7p : kh\u00f4 mi\u1ec7ng, kh\u00e1t nhi\u1ec1u.<\/li>\n<li>Hi\u1ebfm g\u1eb7p : nhi\u1ec5m toan ceton do SGLT2, suy th\u1eadn c\u1ea5p.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng c\u00f9ng thu\u1ed1c l\u1ee3i ti\u1ec3u quai ho\u1eb7c thiazide do t\u0103ng nguy c\u01a1 h\u1ea1 huy\u1ebft \u00e1p t\u01b0 th\u1ebf.<\/li>\n<li>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng sulfonylurea ho\u1eb7c insulin do t\u0103ng nguy c\u01a1 h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft nghi\u00eam tr\u1ecdng.<\/li>\n<li>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng cimetidine do l\u00e0m gi\u1ea3m th\u1ea3i tr\u1eeb metformin qua \u1ed1ng th\u1eadn.<\/li>\n<li>Th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00f9ng zonisamide, acetazolamide, topiramate do c\u00f3 th\u1ec3 g\u00e2y toan chuy\u1ec3n h\u00f3a.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ch\u1ec9 d\u00f9ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa khi l\u1ee3i \u00edch v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>B\u00e1o ngay v\u1edbi b\u00e1c s\u0129 \u0111i\u1ec1u tr\u1ecb \u0111\u1ec3 ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng k\u1ecbp th\u1eddi.<\/p>\n<h2>Jardiance Duo 12.5mg\/850mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Jardiance Duo 12.5mg\/850mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 s\u1ea3n ph\u1ea9m c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng t\u00e1c d\u1ee5ng v\u1edbi nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/glyxambi-25mg-5mg\/\">Thu\u1ed1c Glyxambi 25mg\/5mg<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Boehringer Ingelheim pharma GmbH &amp; Co. KG. Thu\u1ed1c d\u00f9ng \u0111i\u1ec1u tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng type 2.<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/nady-empag-10\/\">Nady-Empag 10<\/a> ch\u1ee9a Empagliflozin h\u00e0m l\u01b0\u1ee3ng 10mg, \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u1ec3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft cho b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng t\u00fdp 2 khi ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng v\u00e0 luy\u1ec7n t\u1eadp kh\u00f4ng \u0111\u1ee7 hi\u1ec7u qu\u1ea3.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>1. H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng \u0111\u01b0\u1ee3c C\u1ee5c qu\u1ea3n l\u00fd ph\u00ea duy\u1ec7t. Xem ngay <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/jardiance-duo-12-5mg-850mg-huong-dan-su-dung.pdf\">T\u1ea0I \u0110\u00c2Y<\/a>.<\/p>\n<p>2. Martin Ridderstrale. Robbyna Svaerd, Cordula Zeller, Gabriel Kim, Hans J Woerle, Uli C Broedl (2013), Rationale, design and baseline characteristics of a 4-year (208-week) phase III trial of empagliflozin, an SGLT2 inhibitor, versus glimepiride as add-on to metformin in patients with type 2 diabetes mellitus with insufficient glycemic control. Truy c\u1eadp ng\u00e0y 27\/06\/2025 t\u1eeb <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3844307\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3844307\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Jardiance Duo 12.5mg\/850mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh\u00a0ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft \u1edf b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng type 2 khi \u0111i\u1ec1u tr\u1ecb \u0111\u01a1n l\u1ebb b\u1eb1ng metformin ho\u1eb7c empagliflozin kh\u00f4ng \u0111\u1ea1t hi\u1ec7u qu\u1ea3.<\/p>\n","protected":false},"author":1,"featured_media":125054,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-125051","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/125051","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=125051"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/125054"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=125051"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=125051"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=125051"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}