{"id":124757,"date":"2025-06-25T22:36:02","date_gmt":"2025-06-25T15:36:02","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=124757"},"modified":"2025-12-23T11:18:07","modified_gmt":"2025-12-23T04:18:07","slug":"kaflovo-500mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/kaflovo-500mg\/","title":{"rendered":"Kaflovo 500mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Kaflovo 500mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Kh\u00e1nh H\u00f2a, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893115886324 (VD-33460-19).<\/strong><\/p>\n<h2>Kaflovo 500mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Kaflovo 500mg<\/strong> c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n ho\u1ea1t ch\u1ea5t ch\u00ednh <strong>Levofloxacin<\/strong> (d\u01b0\u1edbi d\u1ea1ng Levofloxacin hemihydrate) 500mg.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893115886324 (VD-33460-19)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 10 v\u1ec9 x 05 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_124765\" aria-describedby=\"caption-attachment-124765\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-124765\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Kaflovo-500mg.jpg\" alt=\"Kaflovo 500mg \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Kaflovo-500mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Kaflovo-500mg-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Kaflovo-500mg-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Kaflovo-500mg-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-124765\" class=\"wp-caption-text\">Kaflovo 500mg \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Kaflovo 500mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Levofloxacin ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf hai lo\u1ea1i enzyme quan tr\u1ecdng c\u1ee7a vi khu\u1ea9n l\u00e0 DNA gyrase v\u00e0 topoisomerase IV. S\u1ef1 \u1ee9c ch\u1ebf n\u00e0y ng\u0103n c\u1ea3n qu\u00e1 tr\u00ecnh sao ch\u00e9p, s\u1eeda ch\u1eefa v\u00e0 t\u00e1i t\u1ed5 h\u1ee3p DNA c\u1ee7a vi khu\u1ea9n, t\u1eeb \u0111\u00f3 d\u1eabn \u0111\u1ebfn ti\u00eau di\u1ec7t t\u1ebf b\u00e0o vi khu\u1ea9n. Levofloxacin c\u00f3 ph\u1ed5 ho\u1ea1t \u0111\u1ed9ng r\u1ed9ng tr\u00ean c\u1ea3 vi khu\u1ea9n Gram d\u01b0\u01a1ng, Gram \u00e2m v\u00e0 m\u1ed9t s\u1ed1 vi khu\u1ea9n kh\u00f4ng \u0111i\u1ec3n h\u00ecnh.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu: Levofloxacin \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh ch\u00f3ng v\u00e0 g\u1ea7n nh\u01b0 ho\u00e0n to\u00e0n qua \u0111\u01b0\u1eddng u\u1ed1ng (sinh kh\u1ea3 d\u1ee5ng x\u1ea5p x\u1ec9 99%), n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong m\u00e1u \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 1-2 gi\u1edd.<\/li>\n<li>Ph\u00e2n b\u1ed1: Thu\u1ed1c ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i v\u00e0o c\u00e1c m\u00f4 trong c\u01a1 th\u1ec3, \u0111\u1eb7c bi\u1ec7t th\u00e2m nh\u1eadp t\u1ed1t v\u00e0o m\u00f4 ph\u1ed5i v\u1edbi n\u1ed3ng \u0111\u1ed9 cao h\u01a1n trong huy\u1ebft t\u01b0\u01a1ng t\u1eeb 2 \u0111\u1ebfn 5 l\u1ea7n.<\/li>\n<li>Chuy\u1ec3n h\u00f3a: Levofloxacin r\u1ea5t \u00edt b\u1ecb chuy\u1ec3n h\u00f3a trong c\u01a1 th\u1ec3.<\/li>\n<li>Th\u1ea3i tr\u1eeb: Thu\u1ed1c ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua th\u1eadn d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i. Th\u1eddi gian b\u00e1n th\u1ea3i trung b\u00ecnh trong huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 6 \u0111\u1ebfn 8 gi\u1edd.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Kaflovo 500mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Levofloxacin \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho ng\u01b0\u1eddi l\u1edbn (\u226518 tu\u1ed5i) trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p nhi\u1ec5m khu\u1ea9n sau:<\/p>\n<ul>\n<li>Vi\u00eam ph\u1ed5i b\u1ec7nh vi\u1ec7n v\u00e0 vi\u00eam ph\u1ed5i m\u1eafc ph\u1ea3i t\u1ea1i c\u1ed9ng \u0111\u1ed3ng.<\/li>\n<li>Nhi\u1ec5m tr\u00f9ng da v\u00e0 c\u1ea5u tr\u00fac da c\u00f3 ho\u1eb7c kh\u00f4ng c\u00f3 bi\u1ebfn ch\u1ee9ng.<\/li>\n<li>Vi\u00eam tuy\u1ebfn ti\u1ec1n li\u1ec7t do nhi\u1ec5m khu\u1ea9n m\u1ea1n t\u00ednh.<\/li>\n<li>Nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u c\u00f3 bi\u1ebfn ch\u1ee9ng (ho\u1eb7c vi\u00eam \u0111\u00e0i b\u1ec3 th\u1eadn c\u1ea5p) v\u00e0 kh\u00f4ng bi\u1ebfn ch\u1ee9ng.<\/li>\n<li>B\u1ec7nh than (\u0111i\u1ec1u tr\u1ecb sau ph\u01a1i nhi\u1ec5m) v\u00e0 b\u1ec7nh d\u1ecbch h\u1ea1ch.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Kaflovo 500mg<\/h2>\n<p>Li\u1ec1u l\u01b0\u1ee3ng v\u00e0 th\u1eddi gian \u0111i\u1ec1u tr\u1ecb ph\u1ee5 thu\u1ed9c v\u00e0o lo\u1ea1i v\u00e0 m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a nhi\u1ec5m tr\u00f9ng, c\u0169ng nh\u01b0 ch\u1ee9c n\u0103ng th\u1eadn c\u1ee7a b\u1ec7nh nh\u00e2n. Li\u1ec1u th\u00f4ng th\u01b0\u1eddng cho ng\u01b0\u1eddi l\u1edbn c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng dao \u0111\u1ed9ng t\u1eeb 250mg \u0111\u1ebfn 750mg m\u1ed7i ng\u00e0y. C\u1ea7n ph\u1ea3i \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn c\u00f3 \u0111\u1ed9 thanh th\u1ea3i creatinin &lt; 50 mL\/ph\u00fat.<\/p>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Kaflovo 500mg<\/h2>\n<ul>\n<li>Thu\u1ed1c d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng. Nu\u1ed1t c\u1ea3 vi\u00ean, kh\u00f4ng nghi\u1ec1n n\u00e1t hay nhai.<\/li>\n<li>Vi\u00ean n\u00e9n c\u00f3 th\u1ec3 u\u1ed1ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng th\u1ee9c \u0103n.<\/li>\n<li>N\u00ean u\u1ed1ng thu\u1ed1c c\u00e1ch \u00edt nh\u1ea5t 2 gi\u1edd tr\u01b0\u1edbc ho\u1eb7c 2 gi\u1edd sau khi d\u00f9ng c\u00e1c s\u1ea3n ph\u1ea9m ch\u1ee9a cation kim lo\u1ea1i nh\u01b0 thu\u1ed1c kh\u00e1ng axit, sucralfate, c\u00e1c ch\u1ebf ph\u1ea9m ch\u1ee9a s\u1eaft ho\u1eb7c k\u1ebdm.<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Kaflovo 500mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed qu\u00e1 m\u1eabn v\u1edbi Levofloxacin, c\u00e1c kh\u00e1ng sinh quinolone kh\u00e1c ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Kaflovo 500mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>C\u00f3 th\u1ec3 g\u00e2y ph\u1ea3n \u1ee9ng ch\u00e1y n\u1eafng qu\u00e1 m\u1ee9c.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p nh\u1ea5t (\u22653%) bao g\u1ed3m: bu\u1ed3n n\u00f4n, \u0111au \u0111\u1ea7u, ti\u00eau ch\u1ea3y, m\u1ea5t ng\u1ee7, t\u00e1o b\u00f3n, ch\u00f3ng m\u1eb7t.<\/li>\n<li>Vi\u00eam g\u00e2n v\u00e0 \u0111\u1ee9t g\u00e2n: Nguy c\u01a1 t\u0103ng \u1edf b\u1ec7nh nh\u00e2n tr\u00ean 60 tu\u1ed5i, \u0111ang d\u00f9ng corticosteroid, v\u00e0 ng\u01b0\u1eddi gh\u00e9p t\u1ea1ng. C\u00f3 th\u1ec3 x\u1ea3y ra \u1edf g\u00e2n Achilles v\u00e0 c\u00e1c g\u00e2n kh\u00e1c.<\/li>\n<li>B\u1ec7nh th\u1ea7n kinh ngo\u1ea1i bi\u00ean: C\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c tri\u1ec7u ch\u1ee9ng \u0111au, r\u00e1t, t\u00ea, y\u1ebfu v\u00e0 c\u00f3 th\u1ec3 kh\u00f4ng h\u1ed3i ph\u1ee5c.<\/li>\n<li>\u1ea2nh h\u01b0\u1edfng h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng: Nguy c\u01a1 co gi\u1eadt, t\u0103ng \u00e1p l\u1ef1c n\u1ed9i s\u1ecd, r\u1ed1i lo\u1ea1n t\u00e2m th\u1ea7n, \u1ea3o gi\u00e1c, tr\u1ea7m c\u1ea3m.<\/li>\n<li>L\u00e0m tr\u1ea7m tr\u1ecdng th\u00eam b\u1ec7nh nh\u01b0\u1ee3c c\u01a1: C\u00f3 th\u1ec3 l\u00e0m y\u1ebfu c\u01a1 n\u1eb7ng h\u01a1n \u1edf b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed b\u1ec7nh n\u00e0y.<\/li>\n<li>Ph\u1ea3n \u1ee9ng c\u00f3 h\u1ea1i nghi\u00eam tr\u1ecdng kh\u00e1c: Bao g\u1ed3m \u0111\u1ed9c t\u00ednh tr\u00ean gan, ph\u00ecnh v\u00e0 b\u00f3c t\u00e1ch \u0111\u1ed9ng m\u1ea1ch ch\u1ee7, ti\u00eau ch\u1ea3y do <em>Clostridium difficile<\/em>, k\u00e9o d\u00e0i kho\u1ea3ng QT tr\u00ean \u0111i\u1ec7n t\u00e2m \u0111\u1ed3, v\u00e0 r\u1ed1i lo\u1ea1n \u0111\u01b0\u1eddng huy\u1ebft.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Thu\u1ed1c kh\u00e1ng axit, cation kim lo\u1ea1i (s\u1eaft, k\u1ebdm), sucralfate: L\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 s\u1ef1 h\u1ea5p thu c\u1ee7a Levofloxacin.<\/li>\n<li>Warfarin: C\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd ch\u1ec9 s\u1ed1 \u0111\u00f4ng m\u00e1u do Levofloxacin c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00e1u c\u1ee7a Warfarin.<\/li>\n<li>Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb ti\u1ec3u \u0111\u01b0\u1eddng: C\u00f3 th\u1ec3 g\u00e2y r\u1ed1i lo\u1ea1n \u0111\u01b0\u1eddng huy\u1ebft. C\u1ea7n theo d\u00f5i \u0111\u01b0\u1eddng huy\u1ebft c\u1ea9n th\u1eadn.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef c\u00f3 thai: Kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng Levofloxacin trong thai k\u1ef3 tr\u1eeb khi l\u1ee3i \u00edch ti\u1ec1m n\u0103ng v\u01b0\u1ee3t tr\u1ed9i nguy c\u01a1 \u0111\u1ed1i v\u1edbi thai nhi.<\/p>\n<p>Ph\u1ee5 n\u1eef cho con b\u00fa: Kh\u00f4ng n\u00ean d\u00f9ng Levofloxacin khi \u0111ang cho con b\u00fa v\u00ec thu\u1ed1c c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e2n b\u1ed1 v\u00e0o s\u1eefa m\u1eb9<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ch\u00f3ng m\u1eb7t, bu\u1ed3n ng\u1ee7 ho\u1eb7c r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c, \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng t\u1eadp trung. Kh\u00f4ng n\u00ean l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c n\u1ebfu c\u1ea3m th\u1ea5y b\u1ecb \u1ea3nh h\u01b0\u1edfng.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Trong tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u, c\u1ea7n l\u00e0m r\u1ed7ng d\u1ea1 d\u00e0y, theo d\u00f5i b\u1ec7nh nh\u00e2n v\u00e0 duy tr\u00ec \u0111\u1ee7 n\u01b0\u1edbc. Levofloxacin kh\u00f4ng \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf hi\u1ec7u qu\u1ea3 b\u1eb1ng th\u1ea9m ph\u00e2n m\u00e1u ho\u1eb7c th\u1ea9m ph\u00e2n ph\u00fac m\u1ea1c.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Kaflovo 500mg<\/h2>\n<p><a href=\"https:\/\/vnras.com\/drug\/levokilz-500\/\">Thu\u1ed1c Levokilz 500<\/a> th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Levofloxacin h\u00e0m l\u01b0\u1ee3ng 500mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Aurobindo Pharma Limited, \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Andrejs Sitovs, Irene Sartini, Mario Giorgi. Levofloxacin in veterinary medicine: a literature review, truy c\u1eadp ng\u00e0y 25 th\u00e1ng 06 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33964616\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33964616\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Kaflovo 500mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m Kh\u00e1nh H\u00f2a, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893115886324 (VD-33460-19), kh\u00e1ng sinh \u0111i\u1ec1u tr\u1ecb nhi\u1ec5m khu\u1ea9n.<\/p>\n","protected":false},"author":1,"featured_media":124764,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-124757","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/124757","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=124757"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/124764"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=124757"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=124757"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=124757"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}