{"id":124442,"date":"2025-06-24T11:28:59","date_gmt":"2025-06-24T04:28:59","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=124442"},"modified":"2025-12-23T10:16:56","modified_gmt":"2025-12-23T03:16:56","slug":"meseca-fort","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/meseca-fort\/","title":{"rendered":"Meseca Fort"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Meseca Fort \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n t\u1eadp \u0111o\u00e0n Merap, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110454424 (VD-28349-17).<\/strong><\/p>\n<h2>Meseca Fort l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i li\u1ec1u x\u1ecbt (0,137 ml) trong thu\u1ed1c <strong>Meseca Fort <\/strong>ch\u1ee9a:<\/p>\n<ul>\n<li>Azelastine hydrochloride: 137 \u00b5g<\/li>\n<li><strong>Fluticasone<\/strong> propionate: 50 \u00b5g<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110454424 (VD-28349-17)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd 60 li\u1ec1u x\u1ecbt<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_124448\" aria-describedby=\"caption-attachment-124448\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-124448\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Meseca-fort.jpg\" alt=\"Meseca Fort \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng vi\u00eam m\u0169i d\u1ecb \u1ee9ng\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Meseca-fort.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Meseca-fort-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Meseca-fort-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Meseca-fort-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-124448\" class=\"wp-caption-text\">Meseca Fort \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng vi\u00eam m\u0169i d\u1ecb \u1ee9ng<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Meseca Fort<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<ul>\n<li>Azelastine hydrochloride: L\u00e0 ch\u1ea5t kh\u00e1ng histamin H1 c\u00f3 ch\u1ecdn l\u1ecdc, gi\u00fap \u1ed5n \u0111\u1ecbnh t\u1ebf b\u00e0o mast. Ho\u1ea1t ch\u1ea5t n\u00e0y \u1ee9c ch\u1ebf gi\u1ea3i ph\u00f3ng c\u00e1c ch\u1ea5t trung gian g\u00e2y vi\u00eam nh\u01b0 histamin, leukotriene, t\u1eeb \u0111\u00f3 l\u00e0m gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng d\u1ecb \u1ee9ng nh\u01b0 ng\u1ee9a m\u0169i, h\u1eaft h\u01a1i.<\/li>\n<li>Fluticasone propionate: L\u00e0 m\u1ed9t corticosteroid t\u1ed5ng h\u1ee3p, c\u00f3 \u00e1i l\u1ef1c cao v\u1edbi th\u1ee5 th\u1ec3 glucocorticoid, mang l\u1ea1i t\u00e1c d\u1ee5ng kh\u00e1ng vi\u00eam v\u00e0 ch\u1ed1ng d\u1ecb \u1ee9ng m\u1ea1nh m\u1ebd. Fluticasone propionate \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p c\u00e1c ch\u1ea5t trung gian g\u00e2y vi\u00eam, gi\u00fap gi\u1ea3m s\u01b0ng, ngh\u1eb9t m\u0169i v\u00e0 c\u00e1c tri\u1ec7u ch\u1ee9ng vi\u00eam kh\u00e1c.<\/li>\n<\/ul>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>Azelastine hydrochloride: H\u1ea5p thu nhanh, \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau kho\u1ea3ng 0,5 gi\u1edd. Ph\u00e2n b\u1ed1 r\u1ed9ng r\u00e3i v\u00e0o c\u00e1c m\u00f4 ngo\u1ea1i vi v\u00e0 li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng. Chuy\u1ec3n h\u00f3a qua nhi\u1ec1u isoenzyme CYP (ch\u1ee7 y\u1ebfu CYP3A4, CYP2D6, CYP2C19) v\u00e0 th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua ph\u00e2n.<\/li>\n<li>Fluticasone propionate: N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau kho\u1ea3ng 1 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng to\u00e0n th\u00e2n khi d\u00f9ng k\u1ebft h\u1ee3p cao h\u01a1n kho\u1ea3ng 50% so v\u1edbi \u0111\u01a1n tr\u1ecb li\u1ec7u. Chuy\u1ec3n h\u00f3a nhanh ch\u00f3ng t\u1ea1i gan b\u1edfi CYP3A4 v\u00e0 th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua m\u1eadt.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Meseca Fort \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<ul>\n<li>Gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a vi\u00eam m\u0169i d\u1ecb \u1ee9ng theo m\u00f9a v\u00e0 vi\u00eam m\u0169i quanh n\u0103m \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 6 tu\u1ed5i tr\u1edf l\u00ean.<\/li>\n<li>D\u00e0nh cho nh\u1eefng \u0111\u1ed1i t\u01b0\u1ee3ng \u0111\u00e3 \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Azelastine hydrochloride ho\u1eb7c Fluticasone propionate \u0111\u01a1n tr\u1ecb nh\u01b0ng kh\u00f4ng \u0111\u1ea1t hi\u1ec7u qu\u1ea3 mong mu\u1ed1n.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Meseca Fort<\/h2>\n<p>M\u1ed7i b\u00ean m\u0169i x\u1ecbt 1 li\u1ec1u x 2 l\u1ea7n\/ng\u00e0y, v\u00e0o bu\u1ed5i s\u00e1ng v\u00e0 bu\u1ed5i t\u1ed1i.<\/p>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Meseca Fort<\/h2>\n<ul>\n<li>V\u1ec7 sinh s\u1ea1ch m\u0169i tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/li>\n<li>M\u1edf n\u1eafp b\u1ea3o v\u1ec7.<\/li>\n<li>Tr\u01b0\u1edbc khi d\u00f9ng l\u1ea7n \u0111\u1ea7u ho\u1eb7c n\u1ebfu kh\u00f4ng s\u1eed d\u1ee5ng trong \u00edt nh\u1ea5t 14 ng\u00e0y, c\u1ea7n x\u1ecbt b\u1ecf v\u00e0i li\u1ec1u cho \u0111\u1ebfn khi xu\u1ea5t hi\u1ec7n s\u01b0\u01a1ng m\u00f9 \u0111\u1ed3ng nh\u1ea5t.<\/li>\n<li>C\u1ea7m th\u1eb3ng \u0111\u1ee9ng l\u1ecd thu\u1ed1c.<\/li>\n<li>Gi\u1eef \u0111\u1ea7u th\u1eb3ng.<\/li>\n<li>\u0110\u1eb7t \u0111\u1ec9nh \u0111\u1ea7u x\u1ecbt c\u1ee7a l\u1ecd v\u00e0o l\u1ed7 m\u0169i, \u1ea5n \u0111\u1ea7u x\u1ecbt theo li\u1ec1u \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh.<\/li>\n<li>Lau s\u1ea1ch \u0111\u1ea7u x\u1ecbt v\u00e0 \u0111\u1eady n\u1eafp l\u1ecd v\u00e0o.<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Meseca Fort trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng d\u00f9ng Meseca Fort cho nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed m\u1eabn c\u1ea3m v\u1edbi Azelastine hydrochloride, Fluticasone propionate ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Meseca Fort<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Fluticasone propionate c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m n\u1ea5m Candida albicans \u1edf m\u0169i v\u00e0 h\u1ecdng. N\u1ebfu ph\u00e1t hi\u1ec7n nhi\u1ec5m tr\u00f9ng, c\u1ea7n \u0111i\u1ec1u tr\u1ecb ph\u00f9 h\u1ee3p v\u00e0 ng\u1eebng Meseca Fort.<\/li>\n<li>S\u1eed d\u1ee5ng li\u1ec1u cao ho\u1eb7c k\u00e9o d\u00e0i c\u00f3 th\u1ec3 g\u00e2y t\u00e1c d\u1ee5ng corticosteroid to\u00e0n th\u00e2n.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>R\u1ea5t th\u01b0\u1eddng g\u1eb7p: Ch\u1ea3y m\u00e1u cam.<\/li>\n<li>Th\u01b0\u1eddng g\u1eb7p: Nh\u1ee9c \u0111\u1ea7u, m\u00f9i v\u1ecb kh\u00f3 ch\u1ecbu (\u0111\u1eafng mi\u1ec7ng).<\/li>\n<li>\u00cdt g\u1eb7p: Kh\u00f3 ch\u1ecbu \u1edf m\u0169i (k\u00edch \u1ee9ng, \u0111au nh\u1ee9c, ng\u1ee9a), h\u1eaft h\u01a1i, kh\u00f4 m\u0169i\/h\u1ecdng, ho, r\u00e1t h\u1ecdng.<\/li>\n<li>Hi\u1ebfm g\u1eb7p: Kh\u00f4 mi\u1ec7ng.<\/li>\n<li>R\u1ea5t hi\u1ebfm g\u1eb7p: Ch\u00f3ng m\u1eb7t, bu\u1ed3n ng\u1ee7, ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn c\u1ea3m (ph\u1ea3n v\u1ec7, ph\u00f9 m\u1ea1ch, ph\u00e1t ban da, co th\u1eaft ph\u1ebf qu\u1ea3n), t\u0103ng nh\u00e3n \u00e1p, \u0111\u1ee5c th\u1ee7y tinh th\u1ec3, th\u1ee7ng v\u00e1ch ng\u0103n m\u0169i, lo\u00e9t ni\u00eam m\u1ea1c m\u0169i, bu\u1ed3n n\u00f4n, ng\u1ee9a, n\u1ed5i m\u1ec1 \u0111ay, m\u1ec7t m\u1ecfi, ki\u1ec7t s\u1ee9c.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>\u0110\u1ed3 u\u1ed1ng c\u00f3 c\u1ed3n v\u00e0 thu\u1ed1c \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng: T\u0103ng nguy c\u01a1 gi\u1ea3m t\u1ec9nh t\u00e1o v\u00e0 \u1ee9c ch\u1ebf h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng.<\/li>\n<li>Ritonavir v\u00e0 c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf CYP3A4 m\u1ea1nh kh\u00e1c: D\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi Ritonavir kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o do l\u00e0m t\u0103ng \u0111\u00e1ng k\u1ec3 n\u1ed3ng \u0111\u1ed9 Fluticasone propionate trong huy\u1ebft t\u01b0\u01a1ng, c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn t\u00e1c d\u1ee5ng to\u00e0n th\u00e2n c\u1ee7a corticosteroid. C\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng v\u1edbi c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf CYP3A4 m\u1ea1nh kh\u00e1c.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u \u0111\u1ea7y \u0111\u1ee7 v\u1ec1 hi\u1ec7u qu\u1ea3 v\u00e0 \u0111\u1ed9 an to\u00e0n c\u1ee7a Meseca Fort tr\u00ean ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa. C\u00e1c nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt cho th\u1ea5y kh\u1ea3 n\u0103ng g\u00e2y qu\u00e1i thai v\u00e0 \u0111\u1ed9c t\u00ednh ph\u00e1t tri\u1ec3n. Do \u0111\u00f3, ch\u1ec9 s\u1eed d\u1ee5ng Meseca Fort trong th\u1eddi k\u1ef3 mang thai n\u1ebfu l\u1ee3i \u00edch \u0111i\u1ec1u tr\u1ecb v\u01b0\u1ee3t tr\u1ed9i h\u01a1n nguy c\u01a1 \u0111\u1ed1i v\u1edbi thai nhi. C\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng cho ph\u1ee5 n\u1eef cho con b\u00fa.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n ng\u1ee7, l\u00e0m gi\u1ea3m s\u1ef1 t\u1ec9nh t\u00e1o g\u00e2y \u1ea3nh h\u01b0\u1edfng l\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<ul>\n<li>Bi\u1ec3u hi\u1ec7n qu\u00e1 li\u1ec1u: V\u1edbi \u0111\u01b0\u1eddng m\u0169i, t\u00e1c d\u1ee5ng qu\u00e1 li\u1ec1u \u00edt \u0111\u01b0\u1ee3c bi\u1ebft r\u00f5. Tuy nhi\u00ean, d\u00f9ng li\u1ec1u cao trong th\u1eddi gian d\u00e0i c\u00f3 th\u1ec3 g\u00e2y \u1ee9c ch\u1ebf t\u1ea1m th\u1eddi ch\u1ee9c n\u0103ng th\u01b0\u1ee3ng th\u1eadn.<\/li>\n<li>X\u1eed tr\u00ed: \u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng. C\u00f3 th\u1ec3 r\u1eeda d\u1ea1 d\u00e0y n\u1ebfu l\u01b0\u1ee3ng thu\u1ed1c nu\u1ed1t ph\u1ea3i l\u1edbn. Kh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u.<\/li>\n<\/ul>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Meseca Fort<\/h2>\n<p><a href=\"https:\/\/vnras.com\/drug\/thuoc-nozeytin-f-15ml\/\">Thu\u1ed1c x\u1ecbt m\u0169i Nozeytin-F 15ml<\/a> \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty CPDP Gia Nguy\u1ec5n, c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n Azelastin hydroclorid 15mg v\u00e0 Fluticason propionat 5,475mg, \u0111i\u1ec1u tr\u1ecb t\u00ecnh tr\u1ea1ng vi\u00eam m\u0169i d\u1ecb \u1ee9ng quanh n\u0103m ho\u1eb7c theo m\u00f9a.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Pongsakorn Tantilipikorn, Virat Kirtsreesakul, Chaweewan Bunnag, Mukda Vangveeravong, Sanguansak Thanaviratananich, Supinda Chusakul. The Use of Azelastine Hydrochloride\/Fluticasone Propionate in the Management of Allergic Rhinitis in Asia: A Review, truy c\u1eadp ng\u00e0y 24 th\u00e1ng 06 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39045291\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/39045291\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Meseca Fort \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n t\u1eadp \u0111o\u00e0n Merap, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110454424 (VD-28349-17), \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng vi\u00eam m\u0169i d\u1ecb \u1ee9ng.<\/p>\n","protected":false},"author":1,"featured_media":124445,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-124442","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/124442","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=124442"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/124445"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=124442"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=124442"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=124442"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}