{"id":124216,"date":"2025-06-21T16:57:23","date_gmt":"2025-06-21T09:57:23","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=124216"},"modified":"2025-07-24T11:48:06","modified_gmt":"2025-07-24T04:48:06","slug":"natrixam-1-5mg-10mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/natrixam-1-5mg-10mg\/","title":{"rendered":"Natrixam 1.5mg\/10mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Natrixam 1.5mg\/10mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Les Laboratoires Servier Industrie, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 300110029723 (VN3-6-17).<\/strong><\/p>\n<h2>Natrixam 1.5mg\/10mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>M\u1ed7i vi\u00ean n\u00e9n <strong>Natrixam 1.5mg\/10mg<\/strong> ch\u1ee9a hai ho\u1ea1t ch\u1ea5t:<\/p>\n<ul>\n<li>Indapamide: 1.5mg<\/li>\n<li>Amlodipine: 10mg<\/li>\n<\/ul>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 300110029723 (VN3-6-17)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 6 v\u1ec9 x 5 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: France<\/p>\n<figure id=\"attachment_124217\" aria-describedby=\"caption-attachment-124217\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-124217\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Natrixam-1.5mg10mg.jpg\" alt=\"Natrixam 1.5mg\/10mg \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Natrixam-1.5mg10mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Natrixam-1.5mg10mg-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Natrixam-1.5mg10mg-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Natrixam-1.5mg10mg-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-124217\" class=\"wp-caption-text\">Natrixam 1.5mg\/10mg \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Natrixam 1.5mg\/10mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<ul>\n<li>Indapamide (1.5mg): L\u00e0 m\u1ed9t thu\u1ed1c l\u1ee3i ti\u1ec3u nh\u00f3m sulfonamide c\u00f3 t\u00e1c d\u1ee5ng t\u01b0\u01a1ng t\u1ef1 thiazide. Indapamide ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf t\u00e1i h\u1ea5p thu natri \u1edf th\u1eadn, t\u0103ng \u0111\u00e0o th\u1ea3i natri, clorid, kali v\u00e0 magie qua n\u01b0\u1edbc ti\u1ec3u. \u0110i\u1ec1u n\u00e0y kh\u00f4ng ch\u1ec9 gi\u00fap gi\u1ea3m th\u1ec3 t\u00edch d\u1ecbch c\u01a1 th\u1ec3 m\u00e0 c\u00f2n c\u00f3 t\u00e1c d\u1ee5ng gi\u00e3n m\u1ea1ch tr\u1ef1c ti\u1ebfp, g\u00f3p ph\u1ea7n h\u1ea1 huy\u1ebft \u00e1p. \u0110\u1eb7c bi\u1ec7t, Indapamide 1.5mg \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i, \u0111\u1ea3m b\u1ea3o n\u1ed3ng \u0111\u1ed9 thu\u1ed1c \u1ed5n \u0111\u1ecbnh trong m\u00e1u.<\/li>\n<li>Amlodipine (10mg): Thu\u1ed9c nh\u00f3m thu\u1ed1c ch\u1eb9n k\u00eanh calci dihydropyridine. Amlodipine t\u00e1c \u0111\u1ed9ng tr\u1ef1c ti\u1ebfp l\u00ean c\u01a1 tr\u01a1n m\u1ea1ch m\u00e1u, g\u00e2y gi\u00e3n m\u1ea1ch v\u00e0 gi\u1ea3m s\u1ee9c c\u1ea3n ngo\u1ea1i bi\u00ean, t\u1eeb \u0111\u00f3 l\u00e0m h\u1ea1 huy\u1ebft \u00e1p. C\u01a1 ch\u1ebf n\u00e0y kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn chuy\u1ec3n h\u00f3a glucose hay lipid m\u00e1u, l\u00e0m cho Amlodipine tr\u1edf th\u00e0nh l\u1ef1a ch\u1ecdn ph\u00f9 h\u1ee3p cho b\u1ec7nh nh\u00e2n t\u0103ng huy\u1ebft \u00e1p c\u00f3 k\u00e8m \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng.<\/li>\n<\/ul>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>Indapamide (gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i): H\u1ea5p thu nhanh, \u0111\u1ea1t \u0111\u1ec9nh sau ~12 gi\u1edd. G\u1eafn protein 79%. Th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u (70%) v\u00e0 ph\u00e2n (22%), b\u00e1n th\u1ea3i ~18 gi\u1edd. D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc kh\u00f4ng \u0111\u1ed5i \u1edf suy th\u1eadn.<\/li>\n<li>Amlodipine (gi\u1ea3i ph\u00f3ng t\u1ee9c th\u1eddi): H\u1ea5p thu t\u1ed1t, \u0111\u1ea1t \u0111\u1ec9nh sau ~6-12 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng 64-80%. G\u1eafn protein ~97.5%. Chuy\u1ec3n h\u00f3a \u1edf gan, th\u1ea3i tr\u1eeb ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u. B\u00e1n th\u1ea3i ~35-50 gi\u1edd (d\u00f9ng 1 l\u1ea7n\/ng\u00e0y). L\u1ecdc m\u00e1u kh\u00f4ng lo\u1ea1i b\u1ecf \u0111\u01b0\u1ee3c.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Natrixam 1.5mg\/10mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Natrixam 1.5mg\/10mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh thay th\u1ebf cho b\u1ec7nh nh\u00e2n \u0111\u00e3 ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p t\u1ed1t v\u1edbi Indapamide v\u00e0 Amlodipine d\u00f9ng ri\u00eang r\u1ebd \u1edf c\u00f9ng h\u00e0m l\u01b0\u1ee3ng. Thu\u1ed1c kh\u00f4ng d\u00f9ng cho \u0111i\u1ec1u tr\u1ecb ban \u0111\u1ea7u.<\/p>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Natrixam 1.5mg\/10mg<\/h2>\n<p>U\u1ed1ng 1 vi\u00ean\/l\u1ea7n x 1 l\u1ea7n\/ng\u00e0y. Thu\u1ed1c n\u00ean \u0111\u01b0\u1ee3c u\u1ed1ng v\u00e0o bu\u1ed5i s\u00e1ng, nu\u1ed1t nguy\u00ean vi\u00ean v\u1edbi n\u01b0\u1edbc, kh\u00f4ng nhai ho\u1eb7c b\u1ebb.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Natrixam 1.5mg\/10mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>M\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c, sulfonamide kh\u00e1c ho\u1eb7c d\u1eabn ch\u1ea5t dihydropyridine.<\/li>\n<li>Suy th\u1eadn n\u1eb7ng, suy gan n\u1eb7ng.<\/li>\n<li>H\u1ea1 kali m\u00e1u.<\/li>\n<li>Ph\u1ee5 n\u1eef cho con b\u00fa.<\/li>\n<li>H\u1ea1 huy\u1ebft \u00e1p nghi\u00eam tr\u1ecdng, s\u1ed1c (bao g\u1ed3m s\u1ed1c tim), t\u1eafc ngh\u1ebdn \u0111\u01b0\u1eddng ra t\u00e2m th\u1ea5t tr\u00e1i, suy tim kh\u00f4ng \u1ed5n \u0111\u1ecbnh sau nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Natrixam 1.5mg\/10mg<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>B\u1ec7nh nh\u00e2n n\u00ean tr\u00e1nh ti\u1ebfp x\u00fac tr\u1ef1c ti\u1ebfp v\u1edbi \u00e1nh n\u1eafng m\u1eb7t tr\u1eddi ho\u1eb7c tia UVA nh\u00e2n t\u1ea1o.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>C\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 ph\u1ed5 bi\u1ebfn th\u01b0\u1eddng g\u1eb7p c\u1ee7a Natrixam bao g\u1ed3m: h\u1ea1 kali huy\u1ebft, bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t, nh\u1ee9c \u0111\u1ea7u, r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c, tim \u0111\u1eadp nhanh, \u0111\u1ecf b\u1eebng m\u1eb7t, kh\u00f3 th\u1edf, \u0111au b\u1ee5ng, bu\u1ed3n n\u00f4n, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a, ti\u00eau ch\u1ea3y, t\u00e1o b\u00f3n, ph\u00e1t ban, s\u01b0ng m\u1eaft c\u00e1 ch\u00e2n, chu\u1ed9t r\u00fat, ph\u00f9 n\u1ec1, m\u1ec7t m\u1ecfi<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Lithium: T\u0103ng n\u1ed3ng \u0111\u1ed9 Lithium trong m\u00e1u, c\u00f3 nguy c\u01a1 qu\u00e1 li\u1ec1u.<\/li>\n<li>Thu\u1ed1c g\u00e2y xo\u1eafn \u0111\u1ec9nh: T\u0103ng nguy c\u01a1 lo\u1ea1n nh\u1ecbp th\u1ea5t, \u0111\u1eb7c bi\u1ec7t khi h\u1ea1 kali m\u00e1u.<\/li>\n<li>NSAID: Gi\u1ea3m t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p v\u00e0 t\u0103ng nguy c\u01a1 suy th\u1eadn c\u1ea5p.<\/li>\n<li>ACEI: T\u0103ng nguy c\u01a1 h\u1ea1 huy\u1ebft \u00e1p c\u1ea5p v\u00e0 suy th\u1eadn.<\/li>\n<li>C\u00e1c thu\u1ed1c g\u00e2y h\u1ea1 kali kh\u00e1c: T\u0103ng nguy c\u01a1 h\u1ea1 kali m\u00e1u.<\/li>\n<li>B\u01b0\u1edfi\/n\u01b0\u1edbc \u00e9p b\u01b0\u1edfi: T\u0103ng sinh kh\u1ea3 d\u1ee5ng c\u1ee7a Amlodipine, d\u1eabn \u0111\u1ebfn t\u0103ng t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p.<\/li>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf CYP3A4 (vd: clarithromycin): T\u0103ng n\u1ed3ng \u0111\u1ed9 Amlodipine trong m\u00e1u.<\/li>\n<li>Tacrolimus, Cyclosporin, Simvastatin: Amlodipine c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 c\u00e1c thu\u1ed1c n\u00e0y.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<ul>\n<li>Thai k\u1ef3: Kh\u00f4ng khuy\u1ebfn c\u00e1o. C\u1ea7n c\u00e2n nh\u1eafc k\u1ef9 l\u1ee3i \u00edch\/nguy c\u01a1, ch\u1ec9 d\u00f9ng khi th\u1eadt c\u1ea7n thi\u1ebft theo ch\u1ec9 \u0111\u1ecbnh b\u00e1c s\u0129.<\/li>\n<li>Cho con b\u00fa: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh. C\u1ea3 hai ho\u1ea1t ch\u1ea5t c\u00f3 th\u1ec3 v\u00e0o s\u1eefa m\u1eb9, g\u00e2y nguy hi\u1ec3m cho tr\u1ebb.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y hoa m\u1eaft, \u0111au \u0111\u1ea7u, m\u1ec7t m\u1ecfi, bu\u1ed3n n\u00f4n, \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng ph\u1ea3n \u1ee9ng.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<ul>\n<li>Indapamide: G\u00e2y m\u1ea5t c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i (h\u1ea1 Na, K), bu\u1ed3n n\u00f4n, h\u1ea1 huy\u1ebft \u00e1p, l\u00fa l\u1eabn. X\u1eed tr\u00ed: R\u1eeda d\u1ea1 d\u00e0y, than ho\u1ea1t t\u00ednh, b\u00f9 \u0111i\u1ec7n gi\u1ea3i.<\/li>\n<li>Amlodipine: G\u00e2y gi\u00e3n m\u1ea1ch qu\u00e1 m\u1ee9c, h\u1ea1 huy\u1ebft \u00e1p n\u1eb7ng, nh\u1ecbp tim nhanh. X\u1eed tr\u00ed: H\u1ed7 tr\u1ee3 tim m\u1ea1ch (theo d\u00f5i h\u00f4 h\u1ea5p, tu\u1ea7n ho\u00e0n), d\u00f9ng thu\u1ed1c co m\u1ea1ch, Calcium gluconate t\u0129nh m\u1ea1ch. Than ho\u1ea1t t\u00ednh c\u00f3 th\u1ec3 d\u00f9ng s\u1edbm. L\u1ecdc m\u00e1u kh\u00f4ng hi\u1ec7u qu\u1ea3.<\/li>\n<\/ul>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>D Z Kobalava, K E Shavarova. Clinical Features of Arterial Hypertension in the Elderly and Senile Age and the Rationale for Using the Combination of Amlodipine\/Indapamide-retard, truy c\u1eadp ng\u00e0y 21 th\u00e1ng 06 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29041894\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/29041894\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Natrixam 1.5mg\/10mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Les Laboratoires Servier Industrie, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 300110029723 (VN3-6-17), \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p.<\/p>\n","protected":false},"author":1,"featured_media":124218,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-124216","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/124216","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=124216"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/124218"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=124216"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=124216"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=124216"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}