{"id":124143,"date":"2025-06-21T14:53:25","date_gmt":"2025-06-21T07:53:25","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=124143"},"modified":"2025-07-24T11:48:07","modified_gmt":"2025-07-24T04:48:07","slug":"neginol-5","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/neginol-5\/","title":{"rendered":"Neginol 5"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Neginol 5 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c H\u1eadu Giang &#8211; Chi nh\u00e1nh nh\u00e0 m\u00e1y d\u01b0\u1ee3c ph\u1ea9m DHG t\u1ea1i H\u1eadu Giang, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110211923.<\/strong><\/p>\n<h2>Neginol 5 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i vi\u00ean n\u00e9n <strong>Neginol 5<\/strong>, th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 <strong>Nebivolol<\/strong> 5mg (d\u01b0\u1edbi d\u1ea1ng nebivolol hydroclorid) c\u00f9ng v\u1edbi c\u00e1c t\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110211923<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_124144\" aria-describedby=\"caption-attachment-124144\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-124144\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Neginol-5.jpg\" alt=\"Neginol 5 \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Neginol-5.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Neginol-5-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Neginol-5-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Neginol-5-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-124144\" class=\"wp-caption-text\">Neginol 5 \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Neginol 5<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Nebivolol l\u00e0 m\u1ed9t thu\u1ed1c ch\u1eb9n beta-1 ch\u1ecdn l\u1ecdc, mang l\u1ea1i hai t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd ch\u00ednh:<\/p>\n<ul>\n<li>\u0110\u1ed1i kh\u00e1ng ch\u1ecdn l\u1ecdc v\u00e0 c\u1ea1nh tranh th\u1ee5 th\u1ec3 beta-1: T\u00e1c d\u1ee5ng n\u00e0y gi\u00fap gi\u1ea3m nh\u1ecbp tim v\u00e0 s\u1ee9c co b\u00f3p c\u01a1 tim, t\u1eeb \u0111\u00f3 gi\u1ea3m cung l\u01b0\u1ee3ng tim v\u00e0 h\u1ea1 huy\u1ebft \u00e1p.<\/li>\n<li>G\u00e2y gi\u00e3n m\u1ea1ch nh\u1eb9: Nebivolol t\u01b0\u01a1ng t\u00e1c v\u1edbi con \u0111\u01b0\u1eddng L-arginin nitric oxid (NO), th\u00fac \u0111\u1ea9y gi\u1ea3i ph\u00f3ng NO t\u1eeb n\u1ed9i m\u1ea1c m\u1ea1ch m\u00e1u, gi\u00fap gi\u00e3n m\u1ea1ch v\u00e0 gi\u1ea3m s\u1ee9c c\u1ea3n m\u1ea1ch m\u00e1u ngo\u1ea1i vi. S\u1ef1 k\u1ebft h\u1ee3p hai c\u01a1 ch\u1ebf n\u00e0y mang l\u1ea1i hi\u1ec7u qu\u1ea3 h\u1ea1 huy\u1ebft \u00e1p to\u00e0n di\u1ec7n.<\/li>\n<\/ul>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu: Sinh kh\u1ea3 d\u1ee5ng c\u1ee7a thu\u1ed1c thay \u0111\u1ed5i t\u00f9y thu\u1ed9c v\u00e0o c\u00e1 th\u1ec3 do s\u1ef1 \u0111a h\u00ecnh di truy\u1ec1n c\u1ee7a enzym chuy\u1ec3n h\u00f3a.<\/li>\n<li>Ph\u00e2n b\u1ed1: Thu\u1ed1c li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (tr\u00ean 97%), ch\u1ee7 y\u1ebfu l\u00e0 albumin.<\/li>\n<li>Chuy\u1ec3n h\u00f3a: Nebivolol \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a r\u1ed9ng r\u00e3i qua qu\u00e1 tr\u00ecnh hydroxyl h\u00f3a v\u00e0 glucuronid h\u00f3a, v\u1edbi s\u1ef1 tham gia quan tr\u1ecdng c\u1ee7a enzym CYP2D6, t\u1ea1o ra c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh.<\/li>\n<li>Th\u1ea3i tr\u1eeb: Kho\u1ea3ng 38% li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 48% qua ph\u00e2n. Th\u1eddi gian b\u00e1n th\u1ea3i trung b\u00ecnh \u1edf ng\u01b0\u1eddi chuy\u1ec3n h\u00f3a nhanh l\u00e0 10 gi\u1edd.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Neginol 5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<ul>\n<li>T\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n: \u0110i\u1ec1u tr\u1ecb h\u1ea1 huy\u1ebft \u00e1p \u1edf b\u1ec7nh nh\u00e2n c\u00f3 huy\u1ebft \u00e1p cao kh\u00f4ng r\u00f5 nguy\u00ean nh\u00e2n.<\/li>\n<li>Suy tim m\u1ea1n t\u00ednh (CHF): \u0110\u01b0\u1ee3c s\u1eed d\u1ee5ng ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb chu\u1ea9n \u0111\u1ec3 ki\u1ec3m so\u00e1t suy tim m\u1ea1n t\u00ednh \u1ed5n \u0111\u1ecbnh m\u1ee9c \u0111\u1ed9 nh\u1eb9 \u0111\u1ebfn trung b\u00ecnh \u1edf b\u1ec7nh nh\u00e2n t\u1eeb 70 tu\u1ed5i tr\u1edf l\u00ean.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Neginol 5<\/h2>\n<p>T\u0103ng huy\u1ebft \u00e1p (ng\u01b0\u1eddi l\u1edbn):<\/p>\n<ul>\n<li>Li\u1ec1u kh\u1edfi \u0111\u1ea7u th\u00f4ng th\u01b0\u1eddng: 1 vi\u00ean (5 mg) m\u1ed7i ng\u00e0y, u\u1ed1ng v\u00e0o c\u00f9ng m\u1ed9t th\u1eddi \u0111i\u1ec3m.<\/li>\n<li>Hi\u1ec7u qu\u1ea3 h\u1ea1 huy\u1ebft \u00e1p r\u00f5 r\u1ec7t sau 1-2 tu\u1ea7n, hi\u1ec7u qu\u1ea3 t\u1ed1i \u0111a c\u00f3 th\u1ec3 \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 4 tu\u1ea7n.<\/li>\n<li>C\u00f3 th\u1ec3 ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c h\u1ea1 huy\u1ebft \u00e1p kh\u00e1c, v\u00ed d\u1ee5 hydroclorothiazid.<\/li>\n<li>Ng\u01b0\u1eddi cao tu\u1ed5i (&gt;65 tu\u1ed5i): Kh\u1edfi \u0111\u1ea7u 2,5 mg\/ng\u00e0y, c\u00f3 th\u1ec3 t\u0103ng l\u00ean 5 mg\/ng\u00e0y. Th\u1eadn tr\u1ecdng \u0111\u1eb7c bi\u1ec7t v\u1edbi b\u1ec7nh nh\u00e2n tr\u00ean 75 tu\u1ed5i.<\/li>\n<li>B\u1ec7nh nh\u00e2n suy gan v\u00e0 tr\u1ebb em (&lt;18 tu\u1ed5i): Kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng do h\u1ea1n ch\u1ebf d\u1eef li\u1ec7u.<\/li>\n<\/ul>\n<p>Suy tim m\u1ea1n t\u00ednh \u1ed5n \u0111\u1ecbnh:<\/p>\n<ul>\n<li>Li\u1ec1u d\u00f9ng c\u1ea7n \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh t\u1eeb t\u1eeb, t\u0103ng d\u1ea7n d\u01b0\u1edbi s\u1ef1 gi\u00e1m s\u00e1t c\u1ee7a b\u00e1c s\u0129 chuy\u00ean khoa.<\/li>\n<li>Ph\u00e1c \u0111\u1ed3 t\u0103ng li\u1ec1u: Kh\u1edfi \u0111\u1ea7u 1,25 mg\/ng\u00e0y, sau \u0111\u00f3 t\u0103ng d\u1ea7n l\u00ean 2,5 mg, 5 mg v\u00e0 t\u1ed1i \u0111a 10 mg\/ng\u00e0y, c\u00e1ch nhau 1-2 tu\u1ea7n.<\/li>\n<li>Kh\u00f4ng \u0111\u01b0\u1ee3c ng\u1eebng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t; n\u1ebfu c\u1ea7n ng\u1eebng, ph\u1ea3i gi\u1ea3m li\u1ec1u t\u1eeb t\u1eeb (gi\u1ea3m n\u1eeda li\u1ec1u m\u1ed7i tu\u1ea7n) \u0111\u1ec3 tr\u00e1nh l\u00e0m tr\u1ea7m tr\u1ecdng th\u00eam t\u00ecnh tr\u1ea1ng suy tim.<\/li>\n<li>B\u1ec7nh nh\u00e2n suy th\u1eadn n\u1eb7ng (creatinin huy\u1ebft thanh \u2265250 \u00b5mol\/L) v\u00e0 suy gan: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh ho\u1eb7c kh\u00f4ng khuy\u1ebfn c\u00e1o.<\/li>\n<\/ul>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Neginol 5<\/h2>\n<p>Thu\u1ed1c Neginol 5 \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng, c\u00f3 th\u1ec3 u\u1ed1ng trong ho\u1eb7c ngo\u00e0i b\u1eefa \u0103n.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Neginol 5 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Qu\u00e1 m\u1eabn v\u1edbi nebivolol ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o trong c\u00f4ng th\u1ee9c b\u00e0o ch\u1ebf c\u1ee7a thu\u1ed1c Neginol 5.<\/li>\n<li>R\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng gan n\u1eb7ng ho\u1eb7c suy gan.<\/li>\n<li>Suy tim c\u1ea5p, s\u1ed1c tim, ho\u1eb7c suy tim m\u1ea5t b\u00f9 c\u1ea7n d\u00f9ng thu\u1ed1c co c\u01a1 tim ti\u00eam t\u0129nh m\u1ea1ch.<\/li>\n<li>H\u1ed9i ch\u1ee9ng suy n\u00fat xoang, block xoang nh\u0129, block tim \u0111\u1ed9 2-3 (ch\u01b0a \u0111\u1eb7t m\u00e1y t\u1ea1o nh\u1ecbp).<\/li>\n<li>Ti\u1ec1n s\u1eed hen suy\u1ec5n ho\u1eb7c c\u00e1c t\u00ecnh tr\u1ea1ng g\u00e2y th\u1eaft h\u1eb9p \u0111\u01b0\u1eddng th\u1edf.<\/li>\n<li>U \u1edf tuy\u1ebfn th\u01b0\u1ee3ng th\u1eadn ch\u01b0a \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb \u1ed5n \u0111\u1ecbnh.<\/li>\n<li>M\u1ea5t c\u00e2n b\u1eb1ng pH m\u00e1u (nhi\u1ec5m toan chuy\u1ec3n h\u00f3a).<\/li>\n<li>Nh\u1ecbp tim ch\u1eadm (&lt;60 bpm tr\u01b0\u1edbc \u0111i\u1ec1u tr\u1ecb), h\u1ea1 huy\u1ebft \u00e1p (t\u00e2m thu &lt;90 mmHg).<\/li>\n<li>B\u1ec7nh m\u1ea1ch m\u00e1u ngo\u1ea1i bi\u00ean n\u1eb7ng.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Neginol 5<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>G\u00e2y t\u00ea: Ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb thu\u1ed1c ch\u1eb9n beta khi g\u00e2y m\u00ea c\u00f3 th\u1ec3 gi\u1ea3m nguy c\u01a1 lo\u1ea1n nh\u1ecbp. N\u1ebfu ph\u1ea3i ng\u1eebng, n\u00ean ng\u1eebng \u00edt nh\u1ea5t 24 gi\u1edd tr\u01b0\u1edbc ph\u1eabu thu\u1eadt.<\/li>\n<li>H\u00f4 h\u1ea5p: Th\u1eadn tr\u1ecdng khi d\u00f9ng cho b\u1ec7nh nh\u00e2n b\u1ec7nh ph\u1ed5i t\u1eafc ngh\u1ebdn m\u1ea1n t\u00ednh.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<ul>\n<li>Th\u01b0\u1eddng g\u1eb7p: \u0110au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, d\u1ecb c\u1ea3m, kh\u00f3 th\u1edf, t\u00e1o b\u00f3n, bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y, m\u1ec7t m\u1ecfi, ph\u00f9.<\/li>\n<li>Kh\u00f4ng th\u01b0\u1eddng g\u1eb7p: \u00c1c m\u1ed9ng, phi\u1ec1n mu\u1ed9n, suy gi\u1ea3m th\u1ecb l\u1ef1c, nh\u1ecbp tim ch\u1eadm, suy tim, block nh\u0129 th\u1ea5t, h\u1ea1 huy\u1ebft \u00e1p, co th\u1eaft ph\u1ebf qu\u1ea3n, kh\u00f3 ti\u00eau, \u0111\u1ea7y h\u01a1i, n\u00f4n, ng\u1ee9a, ph\u00e1t ban, b\u1ea5t l\u1ef1c.<\/li>\n<li>R\u1ea5t hi\u1ebfm g\u1eb7p: C\u00e1c tr\u01b0\u1eddng h\u1ee3p ng\u1ea5t ho\u1eb7c b\u1ec7nh v\u1ea9y n\u1ebfn tr\u1edf n\u1eb7ng \u0111\u00e3 \u0111\u01b0\u1ee3c ghi nh\u1eadn, tuy nhi\u00ean v\u1edbi t\u1ea7n su\u1ea5t c\u1ef1c k\u1ef3 th\u1ea5p.<\/li>\n<li>Ch\u01b0a r\u00f5 t\u1ea7n su\u1ea5t: M\u1ed9t s\u1ed1 ph\u1ea3n \u1ee9ng nh\u01b0 ph\u00f9 m\u1ea1ch th\u1ea7n kinh, ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn ho\u1eb7c m\u00e0y \u0111ay c\u0169ng c\u00f3 th\u1ec3 x\u1ea3y ra, nh\u01b0ng ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh ch\u00ednh x\u00e1c t\u1ea7n su\u1ea5t.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Thu\u1ed1c ch\u1ed1ng lo\u1ea1n nh\u1ecbp nh\u00f3m I (quinidin, flecainid): T\u0103ng nguy c\u01a1 ch\u1eadm d\u1eabn truy\u1ec1n nh\u0129 th\u1ea5t v\u00e0 gi\u1ea3m s\u1ee9c co b\u00f3p c\u01a1 tim.<\/li>\n<li>Thu\u1ed1c ch\u1eb9n calci nh\u00f3m verapamil\/diltiazem: G\u00e2y gi\u1ea3m s\u1ee9c co b\u00f3p c\u01a1 tim v\u00e0 \u1ee9c ch\u1ebf d\u1eabn truy\u1ec1n nh\u0129 th\u1ea5t.<\/li>\n<li>Thu\u1ed1c h\u1ea1 huy\u1ebft \u00e1p t\u00e1c d\u1ee5ng l\u00ean trung \u01b0\u01a1ng (clonidin, methyldopa): C\u00f3 th\u1ec3 l\u00e0m tr\u1ea7m tr\u1ecdng t\u00ecnh tr\u1ea1ng suy tim v\u00e0 t\u0103ng nguy c\u01a1 &#8220;t\u0103ng huy\u1ebft \u00e1p d\u1ed9i ng\u01b0\u1ee3c&#8221; khi ng\u1eebng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t.<\/li>\n<li>Thu\u1ed1c m\u00ea halogen d\u1ec5 bay h\u01a1i: T\u0103ng nguy c\u01a1 h\u1ea1 huy\u1ebft \u00e1p.<\/li>\n<li>Amiodarone v\u00e0 c\u00e1c thu\u1ed1c ch\u1ed1ng lo\u1ea1n nh\u1ecbp nh\u00f3m III kh\u00e1c: C\u00f3 kh\u1ea3 n\u0103ng l\u00e0m thay \u0111\u1ed5i ho\u1eb7c k\u00e9o d\u00e0i th\u1eddi gian d\u1eabn truy\u1ec1n xung \u0111\u1ed9ng \u0111i\u1ec7n t\u1eeb t\u00e2m nh\u0129 xu\u1ed1ng t\u00e2m th\u1ea5t.<\/li>\n<li>Insulin v\u00e0 c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng d\u1ea1ng u\u1ed1ng: Neginol 5 c\u00f3 th\u1ec3 l\u00e0m lu m\u1edd c\u00e1c d\u1ea5u hi\u1ec7u c\u1ea3nh b\u00e1o c\u1ee7a t\u00ecnh tr\u1ea1ng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft (v\u00ed d\u1ee5: nh\u1ecbp tim nhanh, \u0111\u00e1nh tr\u1ed1ng ng\u1ef1c), khi\u1ebfn b\u1ec7nh nh\u00e2n kh\u00f3 nh\u1eadn bi\u1ebft.<\/li>\n<li>Baclofen, Amifostine: Khi d\u00f9ng \u0111\u1ed3ng th\u1eddi, c\u00e1c ho\u1ea1t ch\u1ea5t n\u00e0y c\u00f3 th\u1ec3 hi\u1ec7p \u0111\u1ed3ng l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a Neginol 5, \u0111\u00f2i h\u1ecfi vi\u1ec7c \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u l\u01b0\u1ee3ng c\u1ee7a thu\u1ed1c \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p.<\/li>\n<li>Glycosid tim, thu\u1ed1c ch\u1eb9n calci nh\u00f3m dihydropyridin, thu\u1ed1c ch\u1ed1ng lo\u1ea1n th\u1ea7n, thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m, NSAID, thu\u1ed1c c\u01b0\u1eddng giao c\u1ea3m.<\/li>\n<li>Thu\u1ed1c \u1ee9c ch\u1ebf CYP2D6 (paroxetin, fluoxetin, quinidin): C\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 nebivolol trong huy\u1ebft t\u01b0\u01a1ng, t\u0103ng nguy c\u01a1 t\u00e1c d\u1ee5ng ph\u1ee5.<\/li>\n<li>Cimetidin, ranitidin, nicardipin: C\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn n\u1ed3ng \u0111\u1ed9 thu\u1ed1c nh\u01b0ng th\u01b0\u1eddng kh\u00f4ng thay \u0111\u1ed5i hi\u1ec7u qu\u1ea3 l\u00e2m s\u00e0ng \u0111\u00e1ng k\u1ec3.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<p>Kh\u00f4ng khuy\u1ebfn c\u00e1o s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai tr\u1eeb khi th\u1ef1c s\u1ef1 c\u1ea7n thi\u1ebft, v\u00e0 c\u1ea7n theo d\u00f5i s\u00e1t thai nhi. Kh\u00f4ng n\u00ean cho con b\u00fa khi \u0111ang d\u00f9ng thu\u1ed1c do nebivolol c\u00f3 th\u1ec3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ch\u00f3ng m\u1eb7t ho\u1eb7c m\u1ec7t m\u1ecfi, c\u1ea7n th\u1eadn tr\u1ecdng khi th\u1ef1c hi\u1ec7n c\u00e1c ho\u1ea1t \u0111\u1ed9ng n\u00e0y.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>C\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd t\u1ea1i khoa ch\u0103m s\u00f3c t\u00edch c\u1ef1c. C\u00f3 th\u1ec3 r\u1eeda d\u1ea1 d\u00e0y, d\u00f9ng than ho\u1ea1t t\u00ednh. X\u1eed tr\u00ed tri\u1ec7u ch\u1ee9ng b\u1eb1ng atropin cho nh\u1ecbp tim ch\u1eadm, truy\u1ec1n d\u1ecbch ho\u1eb7c catecholamin cho h\u1ea1 huy\u1ebft \u00e1p, isoprenalin, dobutamin ho\u1eb7c glucagon cho suy tim. Trong tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng, c\u00f3 th\u1ec3 c\u1ea7n \u0111\u1eb7t m\u00e1y t\u1ea1o nh\u1ecbp.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Neginol 5<\/h2>\n<p>Thu\u1ed1c Nebivolol 5mg c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh l\u00e0 Nebivolol v\u1edbi h\u00e0m l\u01b0\u1ee3ng 5mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty li\u00ean doanh Stada-Vi\u1ec7t Nam, \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00f4 c\u0103n.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Nida Hanif, Ammara Zamir, Imran Imran, Hamid Saeed, Abdul Majeed, Anees Ur Rehman, Waseem Ashraf, Faleh Alqahtani, Muhammad Fawad Rasool. Clinical pharmacokinetics of nebivolol: a systematic review, truy c\u1eadp ng\u00e0y 21 th\u00e1ng 06 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37849071\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/37849071\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Neginol 5 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c H\u1eadu Giang &#8211; Chi nh\u00e1nh nh\u00e0 m\u00e1y d\u01b0\u1ee3c ph\u1ea9m DHG t\u1ea1i H\u1eadu Giang, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110211923.<\/p>\n","protected":false},"author":1,"featured_media":124145,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-124143","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/124143","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=124143"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/124145"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=124143"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=124143"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=124143"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}