{"id":123955,"date":"2025-06-19T23:12:30","date_gmt":"2025-06-19T16:12:30","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=123955"},"modified":"2025-07-24T11:48:10","modified_gmt":"2025-07-24T04:48:10","slug":"peruzi-12-5","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/peruzi-12-5\/","title":{"rendered":"Peruzi 12.5"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Peruzi 12.5 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110663224 (S\u0110K c\u0169: VD-31090-18)<\/strong><\/p>\n<h2>Peruzi 12.5 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ng Peruzi 12.5<\/strong> c\u00f3 ch\u1ee9a: Carvedilol 12,5mg<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110663224 (S\u0110K c\u0169: VD-31090-18)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Peruzi 12.5<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Peruzi 12.5 ch\u1ee9a carvedilol \u2013 m\u1ed9t h\u1ee3p ch\u1ea5t racemic c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf kh\u00f4ng ch\u1ecdn l\u1ecdc th\u1ee5 th\u1ec3 beta-adrenergic k\u1ebft h\u1ee3p v\u1edbi t\u00e1c \u0111\u1ed9ng \u0111\u1ed1i kh\u00e1ng ch\u1ecdn l\u1ecdc l\u00ean th\u1ee5 th\u1ec3 alpha-1. Ngo\u00e0i ra, \u1edf li\u1ec1u cao, thu\u1ed1c c\u00f2n \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn k\u00eanh calci. Nh\u1edd c\u01a1 ch\u1ebf n\u00e0y, Peruzi 12.5 gi\u00fap gi\u00e3n m\u1ea1ch, gi\u1ea3m s\u1ee9c c\u1ea3n ngo\u1ea1i vi m\u00e0 kh\u00f4ng g\u00e2y t\u0103ng nh\u1ecbp tim ph\u1ea3n x\u1ea1. Thu\u1ed1c kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh giao c\u1ea3m n\u1ed9i t\u1ea1i, nh\u01b0ng c\u00f3 t\u00e1c d\u1ee5ng \u1ed5n \u0111\u1ecbnh m\u00e0ng nh\u1eb9 v\u00e0 \u0111\u1eb7c t\u00ednh ch\u1ed1ng oxy h\u00f3a \u0111\u00e1ng k\u1ec3.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<ul>\n<li>H\u1ea5p thu: Sau khi u\u1ed1ng, carvedilol \u0111\u01b0\u1ee3c h\u1ea5p thu qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a nh\u01b0ng sinh kh\u1ea3 d\u1ee5ng to\u00e0n th\u00e2n ch\u1ec9 kho\u1ea3ng 20-25% do chuy\u1ec3n h\u00f3a m\u1ea1nh qua gan b\u01b0\u1edbc \u0111\u1ea7u. N\u1ed3ng \u0111\u1ed9 cao nh\u1ea5t trong m\u00e1u \u0111\u1ea1t sau 1\u20132 gi\u1edd d\u00f9ng thu\u1ed1c.<\/li>\n<li>Ph\u00e2n b\u1ed1: G\u1eafn k\u1ebft cao v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (98\u201399%). Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 kho\u1ea3ng 2 L\/kg, t\u0103ng \u1edf ng\u01b0\u1eddi b\u1ec7nh gan.<\/li>\n<li>Chuy\u1ec3n h\u00f3a: Carvedilol b\u1ecb gan chuy\u1ec3n h\u00f3a m\u1ea1nh th\u00f4ng qua ph\u1ea3n \u1ee9ng glucuronid h\u00f3a v\u00e0 c\u00e1c ph\u1ea3n \u1ee9ng oxy h\u00f3a t\u1ea1o th\u00e0nh c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh (ch\u1ee7 y\u1ebfu tr\u00ean beta).<\/li>\n<li>Th\u1ea3i tr\u1eeb: Th\u1eddi gian b\u00e1n th\u1ea3i t\u1eeb 6\u201310 gi\u1edd. Thu\u1ed1c \u0111\u00e0o th\u1ea3i ch\u1ee7 y\u1ebfu qua ph\u00e2n; ch\u1ec9 kho\u1ea3ng 15% qua th\u1eadn.<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Peruzi 12.5 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p.<\/li>\n<li>H\u1ed7 tr\u1ee3 \u0111i\u1ec1u tr\u1ecb suy tim m\u1ea1n t\u00ednh \u1ed5n \u0111\u1ecbnh (\u0111\u1ed9 trung b\u00ecnh t\u1edbi n\u1eb7ng).<\/li>\n<li>Gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng li\u00ean quan \u0111\u1ebfn \u0111au th\u1eaft ng\u1ef1c \u1ed5n \u0111\u1ecbnh.<\/li>\n<\/ul>\n<figure id=\"attachment_123967\" aria-describedby=\"caption-attachment-123967\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-123967\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Peruzi-125.jpg\" alt=\"Peruzi 12.5\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Peruzi-125.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Peruzi-125-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Peruzi-125-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Peruzi-125-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-123967\" class=\"wp-caption-text\">Thu\u1ed1c Peruzi 12.5 v\u1edbi th\u00e0nh ph\u1ea7n carvedilol \u0111\u01b0\u1ee3c d\u00f9ng trong \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p, suy tim m\u1ea1n v\u00e0 \u0111au th\u1eaft ng\u1ef1c theo c\u01a1 ch\u1ebf \u1ee9c ch\u1ebf kh\u00f4ng ch\u1ecdn l\u1ecdc th\u1ee5 th\u1ec3 beta-adrenergic<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p><em><strong>T\u0103ng huy\u1ebft \u00e1p:<\/strong><\/em><\/p>\n<ul>\n<li>Ng\u01b0\u1eddi l\u1edbn: B\u1eaft \u0111\u1ea7u 1 vi\u00ean\/l\u1ea7n\/ng\u00e0y trong 2 ng\u00e0y, sau \u0111\u00f3 c\u00f3 th\u1ec3 t\u0103ng l\u00ean 2 vi\u00ean\/l\u1ea7n\/ng\u00e0y. T\u1ed1i \u0111a 4 vi\u00ean\/ng\u00e0y.<\/li>\n<li>Ng\u01b0\u1eddi cao tu\u1ed5i: Li\u1ec1u kh\u1edfi \u0111\u1ea7u c\u0169ng l\u00e0 1 vi\u00ean\/l\u1ea7n\/ng\u00e0y, t\u0103ng n\u1ebfu c\u1ea7n sau m\u1ed7i 2 tu\u1ea7n.<\/li>\n<\/ul>\n<p><em><strong>\u0110au th\u1eaft ng\u1ef1c m\u1ea1n t\u00ednh:<\/strong><\/em><\/p>\n<ul>\n<li>Ng\u01b0\u1eddi l\u1edbn: 1 vi\u00ean x 2 l\u1ea7n\/ng\u00e0y trong 2 ng\u00e0y \u0111\u1ea7u, sau \u0111\u00f3 n\u00e2ng l\u00ean 2 vi\u00ean x 2 l\u1ea7n\/ng\u00e0y. T\u1ed1i \u0111a 8 vi\u00ean\/ng\u00e0y (chia 2 l\u1ea7n).<\/li>\n<li>Ng\u01b0\u1eddi cao tu\u1ed5i: Duy tr\u00ec li\u1ec1u t\u1ed1i \u0111a 2 vi\u00ean x 2 l\u1ea7n\/ng\u00e0y.<\/li>\n<\/ul>\n<p><em><strong>Suy tim m\u1ea1n:<\/strong><\/em><\/p>\n<ul>\n<li>Kh\u1edfi \u0111\u1ea7u: 3,125 mg x 2 l\u1ea7n\/ng\u00e0y trong 2 tu\u1ea7n.<\/li>\n<li>C\u00f3 th\u1ec3 t\u0103ng d\u1ea7n l\u00ean 6,25 \u2013 2 vi\u00ean x 2 l\u1ea7n\/ng\u00e0y t\u00f9y kh\u1ea3 n\u0103ng dung n\u1ea1p.<\/li>\n<li>\u0110\u1ed1i v\u1edbi ng\u01b0\u1eddi \u2265 85 kg ho\u1eb7c suy tim nh\u1eb9\/trung b\u00ecnh: t\u1ed1i \u0111a 4 vi\u00ean x 2 l\u1ea7n\/ng\u00e0y.<\/li>\n<\/ul>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<ul>\n<li>D\u00f9ng Peruzi 12.5 b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng, n\u00ean d\u00f9ng c\u00f9ng b\u1eefa \u0103n \u0111\u1ec3 gi\u1ea3m nguy c\u01a1 t\u1ee5t huy\u1ebft \u00e1p t\u01b0 th\u1ebf.<\/li>\n<li>N\u1ebfu d\u00f9ng \u0111\u1ed3ng th\u1eddi thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n, n\u00ean u\u1ed1ng Peruzi 2 gi\u1edd tr\u01b0\u1edbc \u0111\u00f3.<\/li>\n<li>Kh\u00f4ng n\u00ean ng\u01b0ng \u0111\u1ed9t ng\u1ed9t, c\u1ea7n gi\u1ea3m li\u1ec1u t\u1eeb t\u1eeb n\u1ebfu ng\u01b0ng thu\u1ed1c.<\/li>\n<li>N\u1ebfu ng\u01b0ng tr\u00ean 2 tu\u1ea7n, c\u1ea7n kh\u1edfi \u0111\u1ea7u l\u1ea1i t\u1eeb li\u1ec1u th\u1ea5p (3,125 mg x 2 l\u1ea7n\/ng\u00e0y).<\/li>\n<\/ul>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Peruzi 12.5 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi carvedilol ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n t\u00e1 d\u01b0\u1ee3c n\u00e0o c\u00f3 trong Peruzi 12.5<\/li>\n<li>Suy tim m\u1ea5t b\u00f9 ch\u01b0a \u1ed5n \u0111\u1ecbnh.<\/li>\n<li>Hen ph\u1ebf qu\u1ea3n ho\u1eb7c COPD c\u00f3 k\u00e8m co th\u1eaft ph\u1ebf qu\u1ea3n.<\/li>\n<li>Nh\u1ecbp tim ch\u1eadm n\u1eb7ng (&lt; 50 nh\u1ecbp\/ph\u00fat).<\/li>\n<li>Bl\u1ed1c nh\u0129-th\u1ea5t \u0111\u1ed9 II ho\u1eb7c III, h\u1ed9i ch\u1ee9ng n\u00fat xoang b\u1ec7nh l\u00fd.<\/li>\n<li>H\u1ea1 huy\u1ebft \u00e1p n\u1eb7ng (HA t\u00e2m thu &lt; 85 mmHg).<\/li>\n<li>B\u1ec7nh gan c\u00f3 bi\u1ec3u hi\u1ec7n l\u00e2m s\u00e0ng.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>C\u1ea7n gi\u00e1m s\u00e1t ch\u1eb7t khi s\u1eed d\u1ee5ng tr\u00ean ng\u01b0\u1eddi cao tu\u1ed5i ho\u1eb7c c\u00f3 r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng gan, tim, th\u1eadn.<\/li>\n<li>Kh\u00f4ng n\u00ean d\u00f9ng cho ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed ph\u1ea3n \u1ee9ng v\u1edbi m\u00e0u th\u1ef1c ph\u1ea9m (ch\u1ee9a quinolin yellow, allura red&#8230;).<\/li>\n<li>D\u00f9ng th\u1eadn tr\u1ecdng \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng \u2013 c\u00f3 th\u1ec3 che l\u1ea5p d\u1ea5u hi\u1ec7u h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft.<\/li>\n<li>Theo d\u00f5i nh\u1ecbp tim, ch\u1ee9c n\u0103ng th\u1eadn v\u00e0 huy\u1ebft \u00e1p \u0111\u1ecbnh k\u1ef3 khi \u0111i\u1ec1u tr\u1ecb.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Ph\u1ea3n \u1ee9ng ph\u1ee5 th\u01b0\u1eddng nh\u1eb9, x\u1ea3y ra ch\u1ee7 y\u1ebfu khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u00e0 c\u00f3 xu h\u01b0\u1edbng gi\u1ea3m d\u1ea7n. Ch\u00f3ng m\u1eb7t (10%) v\u00e0 \u0111au \u0111\u1ea7u (5%) l\u00e0 ph\u1ed5 bi\u1ebfn nh\u1ea5t. M\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng li\u00ean quan \u0111\u1ebfn li\u1ec1u nh\u01b0 ch\u00f3ng m\u1eb7t n\u1eb7ng, r\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c v\u00e0 ch\u1eadm nh\u1ecbp tim.<\/p>\n<ul>\n<li>R\u1ea5t th\u01b0\u1eddng g\u1eb7p (\u22651\/10): Ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, m\u1ec7t m\u1ecfi, suy tim, h\u1ea1 huy\u1ebft \u00e1p.<\/li>\n<li>Th\u01b0\u1eddng g\u1eb7p (\u22651\/100 \u2013 &lt;1\/10): Vi\u00eam ph\u1ebf qu\u1ea3n, vi\u00eam ph\u1ed5i, thi\u1ebfu m\u00e1u, t\u0103ng c\u00e2n, r\u1ed1i lo\u1ea1n \u0111\u01b0\u1eddng huy\u1ebft, tr\u1ea7m c\u1ea3m, kh\u00f4 m\u1eaft, nh\u1ecbp tim ch\u1eadm, r\u1ed1i lo\u1ea1n tu\u1ea7n ho\u00e0n ngo\u1ea1i bi\u00ean, kh\u00f3 th\u1edf, ti\u00eau ch\u1ea3y, \u0111au c\u01a1, r\u1ed1i lo\u1ea1n ti\u1ec3u ti\u1ec7n.<\/li>\n<li>\u00cdt g\u1eb7p (\u22651\/1000 \u2013 &lt;1\/100): M\u1ea5t ng\u1ee7, l\u00fa l\u1eabn, ng\u1ea5t, d\u1ecb c\u1ea3m, block tim, ph\u00e1t ban, r\u1ee5ng t\u00f3c, r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng d\u01b0\u01a1ng.<\/li>\n<li>Hi\u1ebfm v\u00e0 r\u1ea5t hi\u1ebfm: Gi\u1ea3m ti\u1ec3u c\u1ea7u, ngh\u1eb9t m\u0169i, kh\u00f4 mi\u1ec7ng, d\u1ecb \u1ee9ng, t\u0103ng men gan, ph\u1ea3n \u1ee9ng da nghi\u00eam tr\u1ecdng (Stevens-Johnson), ti\u1ec3u kh\u00f4ng t\u1ef1 ch\u1ee7 \u1edf ph\u1ee5 n\u1eef.<\/li>\n<\/ul>\n<p>L\u01b0u \u00fd:<\/p>\n<ul>\n<li>\u1ede ng\u01b0\u1eddi suy tim, c\u00f3 th\u1ec3 g\u00e2y \u1ee9 d\u1ecbch ho\u1eb7c n\u1eb7ng h\u01a1n t\u00ecnh tr\u1ea1ng b\u1ec7nh.<\/li>\n<li>Thu\u1ed1c c\u00f3 th\u1ec3 l\u00e0m x\u1ea5u ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft \u1edf ng\u01b0\u1eddi ti\u1ec3u \u0111\u01b0\u1eddng.<\/li>\n<li>Ng\u01b0\u1eddi cao tu\u1ed5i kh\u00f4ng ghi nh\u1eadn kh\u00e1c bi\u1ec7t \u0111\u00e1ng k\u1ec3 v\u1ec1 m\u1ee9c \u0111\u1ed9 ADR.<\/li>\n<li>C\u1ea7n d\u00f9ng thu\u1ed1c c\u00f9ng b\u1eefa \u0103n, t\u0103ng li\u1ec1u t\u1eeb t\u1eeb v\u00e0 theo d\u00f5i huy\u1ebft \u00e1p, nh\u1ecbp tim.<\/li>\n<li>Kh\u00f4ng n\u00ean ng\u01b0ng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t. N\u1ebfu ch\u00f3ng m\u1eb7t, n\u00ean n\u1eb1m ngh\u1ec9.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Thu\u1ed1c tim m\u1ea1ch: T\u0103ng nguy c\u01a1 ch\u1eadm nh\u1ecbp, h\u1ea1 huy\u1ebft \u00e1p khi d\u00f9ng c\u00f9ng digoxin, verapamil, diltiazem, amiodaron, thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n.<\/li>\n<li>CYP2D6\/CYP2C9: C\u00e1c thu\u1ed1c nh\u01b0 fluoxetin, paroxetin, quinidin, rifampicin \u1ea3nh h\u01b0\u1edfng chuy\u1ec3n h\u00f3a carvedilol.<\/li>\n<li>Thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft: C\u00f3 th\u1ec3 l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng insulin, c\u1ea7n theo d\u00f5i \u0111\u01b0\u1eddng huy\u1ebft s\u00e1t sao.<\/li>\n<li>NSAIDs: C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a Peruzi.<\/li>\n<li>Thu\u1ed1c g\u00e2y m\u00ea, r\u01b0\u1ee3u: Hi\u1ec7p \u0111\u1ed3ng \u1ee9c ch\u1ebf tim m\u1ea1ch \u2013 c\u1ea7n c\u1ea3nh gi\u00e1c khi ph\u1ed1i h\u1ee3p.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng carvedilol trong thai k\u1ef3 tr\u1eeb khi th\u1ef1c s\u1ef1 c\u1ea7n thi\u1ebft, do nguy c\u01a1 g\u00e2y suy h\u00f4 h\u1ea5p, h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft ho\u1eb7c ch\u1eadm nh\u1ecbp \u1edf thai nhi.<\/p>\n<p>Carvedilol c\u00f3 th\u1ec3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 \u2013 kh\u00f4ng n\u00ean cho con b\u00fa trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y m\u1ec7t m\u1ecfi, ch\u00f3ng m\u1eb7t, l\u00e0m gi\u1ea3m s\u1ef1 t\u1ec9nh t\u00e1o nh\u1ea5t th\u1eddi, \u0111\u1eb7c bi\u1ec7t khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb ho\u1eb7c sau khi t\u0103ng li\u1ec1u.<\/p>\n<p>Kh\u00f4ng khuy\u1ebfn c\u00e1o l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c n\u1ebfu xu\u1ea5t hi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng n\u00e0y.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Bi\u1ec3u hi\u1ec7n: H\u1ea1 huy\u1ebft \u00e1p, nh\u1ecbp tim ch\u1eadm, suy tim, ng\u1eebng tim, co th\u1eaft ph\u1ebf qu\u1ea3n, n\u00f4n, co gi\u1eadt, r\u1ed1i lo\u1ea1n \u00fd th\u1ee9c.<\/p>\n<p>X\u1eed tr\u00ed:<\/p>\n<ul>\n<li>Theo d\u00f5i t\u1ea1i c\u01a1 s\u1edf y t\u1ebf chuy\u00ean khoa.<\/li>\n<li>D\u00f9ng atropin khi nh\u1ecbp ch\u1eadm; glucagon ho\u1eb7c dobutamin \u0111\u1ec3 h\u1ed7 tr\u1ee3 tim.<\/li>\n<li>N\u1ebfu co th\u1eaft ph\u1ebf qu\u1ea3n: d\u00f9ng thu\u1ed1c gi\u00e3n ph\u1ebf qu\u1ea3n d\u1ea1ng kh\u00ed dung ho\u1eb7c ti\u00eam.<\/li>\n<li>Co gi\u1eadt: ti\u00eam diazepam ho\u1eb7c clonazepam.<\/li>\n<li>Kh\u00f4ng l\u1ecdc m\u00e1u \u0111\u01b0\u1ee3c do thu\u1ed1c g\u1eafn m\u1ea1nh v\u00e0o protein huy\u1ebft t\u01b0\u01a1ng.<\/li>\n<li>H\u1ed7 tr\u1ee3 t\u00edch c\u1ef1c k\u00e9o d\u00e0i trong tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng.<\/li>\n<\/ul>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<ul>\n<li>Gi\u1eef Peruzi 12.5 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/li>\n<li>Kh\u00f4ng \u0111\u1ec3 Peruzi 12.5 trong t\u1ea7m v\u1edbi tr\u1ebb em<\/li>\n<li>Kh\u00f4ng s\u1eed d\u1ee5ng Peruzi 12.5 khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Peruzi 12.5 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Peruzi 12.5 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Peruzi 12.5 c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p Peruzi 12.5 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Peruzi 12.5 nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/savi-carvedilol-6-25\/\">SaVi Carvedilol 6.25<\/a> c\u00f3 th\u00e0nh ph\u1ea7n Carvedilol 6.25mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m SaVi, \u0111i\u1ec1u t\u1ecb c\u00e1c b\u1ec7nh l\u00fd v\u1ec1 tim m\u1ea1ch.<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/carvestad-6-25\/\">Carvestad 6.25<\/a> c\u00f3 th\u00e0nh ph\u1ea7n Carvedilol 6.25mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty TNHH Li\u00ean doanh Stellapharm, \u0111i\u1ec1u t\u1ecb c\u00e1c b\u1ec7nh l\u00fd v\u1ec1 tim m\u1ea1ch.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Peruzi 12.5 \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/drugbank.vn\/thuoc\/Peruzi-12-5&amp;VD-31090-18\" rel=\"noopener\">t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 19 th\u00e1ng 6 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/drugbank.vn\/thuoc\/Peruzi-12-5&amp;VD-31090-18\" rel=\"noopener\">https:\/\/drugbank.vn\/thuoc\/Peruzi-12-5&amp;VD-31090-18<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p><span style=\"font-weight: 400;\">Thu\u1ed1c Peruzi 12.5 v\u1edbi th\u00e0nh ph\u1ea7n carvedilol \u0111\u01b0\u1ee3c d\u00f9ng trong \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p, suy tim m\u1ea1n v\u00e0 \u0111au th\u1eaft ng\u1ef1c theo c\u01a1 ch\u1ebf \u1ee9c ch\u1ebf kh\u00f4ng ch\u1ecdn l\u1ecdc th\u1ee5 th\u1ec3 beta-adrenergic<\/span><\/p>\n","protected":false},"author":1,"featured_media":123964,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-123955","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/123955","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=123955"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/123964"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=123955"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=123955"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=123955"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}