{"id":123898,"date":"2025-06-19T15:02:55","date_gmt":"2025-06-19T08:02:55","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=123898"},"modified":"2025-07-24T11:48:11","modified_gmt":"2025-07-24T04:48:11","slug":"opedulox-40","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/opedulox-40\/","title":{"rendered":"Opedulox 40"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y,<\/strong> <a href=\"https:\/\/vnras.com\/drug\/\"><strong>d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng<\/strong><\/a><strong> gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c<\/strong> <strong>Opedulox 40 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m OPV, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 QL\u0110B-624-17.<\/strong><\/p>\n<h2>Opedulox 40 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p><strong>Opedulox 40<\/strong> l\u00e0 thu\u1ed1c k\u00ea \u0111\u01a1n, b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi\u00ean n\u00e9n bao phim, c\u00f3 th\u00e0nh ph\u1ea7n ch\u00ednh <strong>Febuxostat<\/strong> 40mg.<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: QL\u0110B-624-17<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 3 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<figure id=\"attachment_123899\" aria-describedby=\"caption-attachment-123899\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-123899\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Opedulox-40.jpg\" alt=\"Opedulox 40 \u0111i\u1ec1u tr\u1ecb t\u0103ng acid uric\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Opedulox-40.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Opedulox-40-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Opedulox-40-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Opedulox-40-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-123899\" class=\"wp-caption-text\">Opedulox 40 \u0111i\u1ec1u tr\u1ecb t\u0103ng acid uric<\/figcaption><\/figure>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Opedulox 40<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Opedulox 40 ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf enzyme xanthin oxidase \u2013 m\u1ed9t enzyme then ch\u1ed1t trong qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a purin t\u1ea1o ra acid uric. B\u1eb1ng c\u00e1ch n\u00e0y, Febuxostat l\u00e0m gi\u1ea3m \u0111\u00e1ng k\u1ec3 n\u1ed3ng \u0111\u1ed9 acid uric trong huy\u1ebft thanh, t\u1eeb \u0111\u00f3 ng\u0103n ch\u1eb7n s\u1ef1 h\u00ecnh th\u00e0nh v\u00e0 l\u1eafng \u0111\u1ecdng tinh th\u1ec3 urat t\u1ea1i c\u00e1c kh\u1edbp v\u00e0 th\u1eadn.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Febuxostat \u0111\u01b0\u1ee3c h\u1ea5p thu t\u1ed1t v\u00e0 \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau 1 &#8211; 1,5 gi\u1edd. Thu\u1ed1c li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (kho\u1ea3ng 99,2%). Th\u1ea3i tr\u1eeb qua c\u1ea3 gan v\u00e0 th\u1eadn, v\u1edbi th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 5 &#8211; 8 gi\u1edd.<\/p>\n<h2>Thu\u1ed1c Opedulox 40 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>Opedulox 40 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh cho ng\u01b0\u1eddi l\u1edbn b\u1ecb t\u0103ng acid uric m\u1ea1n t\u00ednh khi \u0111\u00e3 c\u00f3 b\u1eb1ng ch\u1ee9ng v\u1ec1 s\u1ef1 l\u1eafng \u0111\u1ecdng urat, bao g\u1ed3m:<\/p>\n<ul>\n<li>Ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed ho\u1eb7c \u0111ang b\u1ecb s\u1ecfi urat.<\/li>\n<li>Ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed ho\u1eb7c \u0111ang b\u1ecb vi\u00eam kh\u1edbp do Gout.<\/li>\n<\/ul>\n<h2>Li\u1ec1u d\u00f9ng c\u1ee7a thu\u1ed1c Opedulox 40<\/h2>\n<ul>\n<li>Li\u1ec1u kh\u1edfi \u0111\u1ea7u: 80 mg\/l\u1ea7n\/ng\u00e0y.<\/li>\n<li>N\u1ebfu sau 2-4 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb, n\u1ed3ng \u0111\u1ed9 acid uric huy\u1ebft thanh v\u1eabn tr\u00ean 6 mg\/dL (357 \u00b5mol\/l), c\u00f3 th\u1ec3 t\u0103ng li\u1ec1u l\u00ean 120 mg\/l\u1ea7n\/ng\u00e0y.<\/li>\n<\/ul>\n<h2>C\u00e1ch d\u00f9ng c\u1ee7a thu\u1ed1c Opedulox 40<\/h2>\n<p>Opedulox 40 d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng, c\u00f3 th\u1ec3 u\u1ed1ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng th\u1ee9c \u0103n.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Opedulox 40 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c n\u00e0y n\u1ebfu b\u1ea1n qu\u00e1 m\u1eabn c\u1ea3m v\u1edbi Febuxostat ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c Opedulox 40<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>R\u1ed1i lo\u1ea1n tim m\u1ea1ch: Kh\u00f4ng khuy\u1ebfn c\u00e1o cho b\u1ec7nh nh\u00e2n thi\u1ebfu m\u00e1u c\u01a1 tim ho\u1eb7c suy tim sung huy\u1ebft.<\/li>\n<li>Ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn: C\u00f3 th\u1ec3 x\u1ea3y ra c\u00e1c ph\u1ea3n \u1ee9ng nghi\u00eam tr\u1ecdng (v\u00ed d\u1ee5: h\u1ed9i ch\u1ee9ng Stevens-Johnson). C\u1ea7n theo d\u00f5i ch\u1eb7t ch\u1ebd v\u00e0 ng\u1eebng thu\u1ed1c ngay n\u1ebfu c\u00f3 d\u1ea5u hi\u1ec7u. Kh\u00f4ng d\u00f9ng l\u1ea1i thu\u1ed1c n\u1ebfu \u0111\u00e3 t\u1eebng m\u1eabn c\u1ea3m.<\/li>\n<li>C\u01a1n Gout c\u1ea5p: Kh\u00f4ng b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb khi \u0111ang c\u00f3 c\u01a1n Gout c\u1ea5p. N\u1ebfu c\u01a1n Gout x\u1ea3y ra trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb, v\u1eabn ti\u1ebfp t\u1ee5c d\u00f9ng thu\u1ed1c.<\/li>\n<li>C\u00e1c t\u00ecnh tr\u1ea1ng kh\u00e1c: Kh\u00f4ng s\u1eed d\u1ee5ng cho b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh \u00e1c t\u00ednh, h\u1ed9i ch\u1ee9ng Lesch-Nyhan ho\u1eb7c ng\u01b0\u1eddi \u0111\u00e3 \u0111\u01b0\u1ee3c thay gh\u00e9p c\u01a1 quan.<\/li>\n<li>Ch\u1ee9c n\u0103ng gan v\u00e0 tuy\u1ebfn gi\u00e1p: C\u1ea7n ki\u1ec3m tra \u0111\u1ecbnh k\u1ef3 ch\u1ee9c n\u0103ng gan v\u00e0 th\u1eadn tr\u1ecdng \u1edf b\u1ec7nh nh\u00e2n c\u00f3 r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng tuy\u1ebfn gi\u00e1p.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c: Thu\u1ed1c c\u00f3 ch\u1ee9a lactose, c\u1ea7n th\u1eadn tr\u1ecdng v\u1edbi ng\u01b0\u1eddi kh\u00f4ng dung n\u1ea1p galactose.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<table width=\"600\">\n<tbody>\n<tr>\n<td width=\"129\">Th\u01b0\u1eddng g\u1eb7p<\/td>\n<td width=\"471\">C\u01a1n Gout c\u1ea5p, \u0111au \u0111\u1ea7u, ti\u00eau ch\u1ea3y, bu\u1ed3n n\u00f4n, b\u1ea5t th\u01b0\u1eddng ch\u1ee9c n\u0103ng gan, ph\u00e1t ban, ph\u00f9 n\u1ec1.<\/td>\n<\/tr>\n<tr>\n<td width=\"129\">\u00cdt g\u1eb7p<\/td>\n<td width=\"471\">Suy th\u1eadn, \u0111au kh\u1edbp, vi\u00eam ph\u1ebf qu\u1ea3n, t\u0103ng huy\u1ebft \u00e1p, ch\u00f3ng m\u1eb7t, t\u0103ng lipid m\u00e1u, \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, t\u0103ng hormon TSH.<\/td>\n<\/tr>\n<tr>\n<td width=\"129\">Hi\u1ebfm g\u1eb7p<\/td>\n<td width=\"471\">Gi\u1ea3m to\u00e0n th\u1ec3 huy\u1ebft c\u1ea7u, ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7, vi\u00eam gan, v\u00e0ng da, h\u1ed9i ch\u1ee9ng Stevens-Johnson, ti\u00eau c\u01a1 v\u00e2n, v.v.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Mercaptopurin\/Azathioprin: Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng \u0111\u1ed3ng th\u1eddi do nguy c\u01a1 t\u0103ng n\u1ed3ng \u0111\u1ed9 v\u00e0 ng\u1ed9 \u0111\u1ed9c.<\/li>\n<li>Theophylin: C\u00f3 th\u1ec3 d\u00f9ng \u0111\u1ed3ng th\u1eddi Febuxostat 80 mg m\u00e0 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3.<\/li>\n<li>Naproxen v\u00e0 c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf glucuronic h\u00f3a: C\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 Febuxostat, nh\u01b0ng th\u01b0\u1eddng kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u.<\/li>\n<li>C\u00e1c ch\u1ea5t c\u1ea3m \u1ee9ng glucuronic h\u00f3a m\u1ea1nh: C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a Febuxostat.<\/li>\n<li>Colchicin\/Indometacin\/Hydroclorothiazid\/Warfarin: C\u00f3 th\u1ec3 d\u00f9ng \u0111\u1ed3ng th\u1eddi m\u00e0 kh\u00f4ng c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 b\u00e0 m\u1eb9 cho con b\u00fa<\/h3>\n<ul>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai: Kh\u00f4ng n\u00ean d\u00f9ng Febuxostat trong th\u1eddi k\u1ef3 mang thai.<\/li>\n<li>B\u00e0 m\u1eb9 cho con b\u00fa: Kh\u00f4ng n\u00ean d\u00f9ng Febuxostat trong khi \u0111ang cho con b\u00fa.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>C\u1ea7n th\u1eadn tr\u1ecdng v\u00ec thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ng\u1ee7 g\u00e0, ch\u00f3ng m\u1eb7t, d\u1ecb c\u1ea3m, m\u1edd m\u1eaft.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u c\u1ea7n \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3.<\/p>\n<h2>S\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 thu\u1ed1c Opedulox 40<\/h2>\n<p><a href=\"https:\/\/vnras.com\/drug\/febuxat-40mg\/\">Thu\u1ed1c Febuxat 40mg<\/a> s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n nghi\u00ean c\u1ee9u v\u00e0 s\u1ea3n xu\u1ea5t d\u01b0\u1ee3c ph\u1ea9m Meracine, c\u00f3 ch\u1ee9a th\u00e0nh ph\u1ea7n Febuxostat 40mg, ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh Gout.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Thomas Bardin, Pascal Richette. The role of febuxostat in gout, truy c\u1eadp ng\u00e0y 19 th\u00e1ng 06 n\u0103m 2025 t\u1eeb <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30601228\/\" rel=\"noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30601228\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Opedulox 40 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty C\u1ed5 ph\u1ea7n D\u01b0\u1ee3c ph\u1ea9m OPV, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 QL\u0110B-624-17, ch\u1ec9 \u0111\u1ecbnh cho ng\u01b0\u1eddi l\u1edbn b\u1ecb t\u0103ng acid uric m\u1ea1n t\u00ednh.<\/p>\n","protected":false},"author":1,"featured_media":123900,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-123898","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/123898","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=123898"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/123900"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=123898"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=123898"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=123898"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}