{"id":123792,"date":"2025-06-18T17:18:50","date_gmt":"2025-06-18T10:18:50","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=123792"},"modified":"2025-07-24T11:48:13","modified_gmt":"2025-07-24T04:48:13","slug":"ravenell-125","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/ravenell-125\/","title":{"rendered":"Ravenell 125"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng s\u1ebd gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n s\u1ea3n ph\u1ea9m thu\u1ed1c Ravenell 125 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa, c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 893110663424.<\/strong><\/p>\n<h2>Ravenell 125 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Th\u00e0nh ph\u1ea7n c\u1ee7a t<strong>hu\u1ed1c Ravenell-125<\/strong> bao g\u1ed3m:<\/p>\n<ul>\n<li>Bosentan (d\u01b0\u1edbi d\u1ea1ng Bosentan monohydrat): 125 mg.<\/li>\n<li>T\u00e1 d\u01b0\u1ee3c v\u1eeba \u0111\u1ee7.<\/li>\n<\/ul>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<figure id=\"attachment_123813\" aria-describedby=\"caption-attachment-123813\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-123813\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Ravenell-125.jpg\" alt=\"Ravenell-125\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Ravenell-125.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Ravenell-125-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Ravenell-125-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Ravenell-125-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-123813\" class=\"wp-caption-text\">Ravenell-125 \u0111i\u1ec1u tr\u1ecb t\u0103ng \u00e1p l\u1ef1c \u0111\u1ed9ng m\u1ea1ch ph\u1ed5i<\/figcaption><\/figure>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 893110663424<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 4 v\u1ec9 x 14 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Ravenell 125<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Bosentan thu\u1ed9c nh\u00f3m ch\u1ea5t \u0111\u1ed1i kh\u00e1ng k\u00e9p v\u1edbi th\u1ee5 th\u1ec3 endothelin A v\u00e0 B. Thu\u1ed1c gi\u00fap gi\u1ea3m s\u1ee9c c\u1ea3n m\u1ea1ch m\u00e1u ph\u1ed5i v\u00e0 to\u00e0n th\u00e2n, t\u1eeb \u0111\u00f3 t\u0103ng cung l\u01b0\u1ee3ng tim m\u00e0 kh\u00f4ng l\u00e0m t\u0103ng nh\u1ecbp tim.<\/p>\n<p>Endothelin-1 (ET-1) l\u00e0 ch\u1ea5t co m\u1ea1ch m\u1ea1nh, g\u00f3p ph\u1ea7n v\u00e0o qu\u00e1 tr\u00ecnh x\u01a1 v\u1eefa, vi\u00eam, t\u0103ng sinh t\u1ebf b\u00e0o v\u00e0 t\u00e1i c\u1ea5u tr\u00fac m\u1ea1ch. N\u1ed3ng \u0111\u1ed9 ET-1 th\u01b0\u1eddng t\u0103ng cao trong nhi\u1ec1u b\u1ec7nh l\u00fd tim m\u1ea1ch nh\u01b0 t\u0103ng \u00e1p \u0111\u1ed9ng m\u1ea1ch ph\u1ed5i, suy tim, x\u01a1 c\u1ee9ng b\u00ec, thi\u1ebfu m\u00e1u c\u01a1 tim v\u00e0 t\u0103ng huy\u1ebft \u00e1p. Bosentan ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch c\u1ea1nh tranh v\u1edbi ET-1 \u0111\u1ec3 \u1ee9c ch\u1ebf th\u1ee5 th\u1ec3 ETA v\u00e0 ETB, v\u1edbi \u00e1i l\u1ef1c cao h\u01a1n cho ETA. Thu\u1ed1c kh\u00f4ng t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn c\u00e1c lo\u1ea1i th\u1ee5 th\u1ec3 kh\u00e1c.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>H\u1ea5p thu: Bosentan c\u00f3 sinh kh\u1ea3 d\u1ee5ng kho\u1ea3ng 50%, kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi th\u1ee9c \u0103n, \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng sau 3\u20135 gi\u1edd.<\/p>\n<p>Ph\u00e2n b\u1ed1: G\u1eafn k\u1ebft &gt;98% v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng, ch\u1ee7 y\u1ebfu l\u00e0 albumin. Kh\u00f4ng th\u00e2m nh\u1eadp v\u00e0o h\u1ed3ng c\u1ea7u, th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 kho\u1ea3ng 18 l\u00edt.<\/p>\n<p>Chuy\u1ec3n h\u00f3a v\u00e0 th\u1ea3i tr\u1eeb: \u0110\u01b0\u1ee3c chuy\u1ec3n h\u00f3a \u1edf gan qua c\u00e1c enzym CYP2C9 v\u00e0 CYP3A4. Th\u1ea3i ch\u1ee7 y\u1ebfu qua ph\u00e2n, d\u01b0\u1edbi 3% qua n\u01b0\u1edbc ti\u1ec3u. Ch\u1ec9 m\u1ed9t ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh d\u01b0\u1ee3c l\u00fd. Sau d\u00f9ng nhi\u1ec1u li\u1ec1u, n\u1ed3ng \u0111\u1ed9 huy\u1ebft t\u01b0\u01a1ng gi\u1ea3m do thu\u1ed1c t\u1ef1 c\u1ea3m \u1ee9ng chuy\u1ec3n h\u00f3a. Bosentan c\u00f3 th\u1ec3 c\u1ea3m \u1ee9ng CYP2C9, CYP3A4, CYP2C19 v\u00e0 P-glycoprotein, nh\u01b0ng kh\u00f4ng \u1ee9c ch\u1ebf \u0111\u00e1ng k\u1ec3 c\u00e1c enzym chuy\u1ec3n h\u00f3a kh\u00e1c.<\/p>\n<h2>Thu\u1ed1c Ravenell-125 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p><strong>Ravenell 125<\/strong> \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb c\u00e1c t\u00ecnh tr\u1ea1ng sau:<\/p>\n<ul>\n<li>T\u0103ng \u00e1p l\u1ef1c \u0111\u1ed9ng m\u1ea1ch ph\u1ed5i nguy\u00ean ph\u00e1t ho\u1eb7c th\u1ee9 ph\u00e1t \u0111\u1ed9 II ho\u1eb7c III.<\/li>\n<li>T\u0103ng \u00e1p l\u1ef1c \u0111\u1ed9ng m\u1ea1ch ph\u1ed5i do x\u01a1 c\u1ee9ng b\u00ec to\u00e0n th\u1ec3, m\u1ed9t b\u1ec7nh m\u00f4 li\u00ean k\u1ebft \u0111\u1eb7c tr\u01b0ng b\u1edfi t\u00ecnh tr\u1ea1ng x\u01a1 h\u00f3a v\u00e0 vi\u00eam h\u1ec7 th\u1ed1ng.<\/li>\n<li>Gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng v\u1ebft lo\u00e9t \u0111\u1ea7u ng\u00f3n tay\/ng\u00f3n ch\u00e2n m\u1edbi \u1edf b\u1ec7nh nh\u00e2n b\u1ecb x\u01a1 c\u1ee9ng b\u00ec ti\u1ebfn tri\u1ec3n, gi\u00fap c\u1ea3i thi\u1ec7n ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh.<\/li>\n<\/ul>\n<p>Nh\u1edd c\u01a1 ch\u1ebf l\u00e0m gi\u00e3n m\u1ea1ch v\u00e0 gi\u1ea3m kh\u00e1ng l\u1ef1c \u0111\u1ed9ng m\u1ea1ch ph\u1ed5i, Ravenell gi\u00fap c\u1ea3i thi\u1ec7n cung l\u01b0\u1ee3ng tim, c\u1ea3i thi\u1ec7n kh\u1ea3 n\u0103ng g\u1eafng s\u1ee9c v\u00e0 gi\u1ea3m tri\u1ec7u ch\u1ee9ng r\u00f5 r\u1ec7t cho b\u1ec7nh nh\u00e2n.<\/p>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>Vi\u1ec7c s\u1eed d\u1ee5ng Ravenell 125 c\u1ea7n c\u00f3 s\u1ef1 ch\u1ec9 \u0111\u1ecbnh v\u00e0 theo d\u00f5i s\u00e1t sao c\u1ee7a b\u00e1c s\u0129 chuy\u00ean khoa tim m\u1ea1ch ho\u1eb7c h\u00f4 h\u1ea5p. Li\u1ec1u d\u00f9ng thay \u0111\u1ed5i t\u00f9y theo l\u1ee9a tu\u1ed5i, t\u00ecnh tr\u1ea1ng b\u1ec7nh l\u00fd v\u00e0 \u0111\u00e1p \u1ee9ng \u0111i\u1ec1u tr\u1ecb c\u1ee7a b\u1ec7nh nh\u00e2n.<\/p>\n<p>Thu\u1ed1c d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng, n\u00ean u\u1ed1ng nguy\u00ean vi\u00ean v\u1edbi n\u01b0\u1edbc l\u1ecdc,\u00a0c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng v\u1edbi th\u1ee9c \u0103n.<\/p>\n<p>N\u00ean u\u1ed1ng v\u00e0o bu\u1ed5i s\u00e1ng v\u00e0 bu\u1ed5i t\u1ed1i v\u00e0o c\u00e1c th\u1eddi \u0111i\u1ec3m c\u1ed1 \u0111\u1ecbnh \u0111\u1ec3 \u0111\u1ea1t hi\u1ec7u qu\u1ea3 t\u1ed1i \u01b0u.<\/p>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<h4>Ng\u01b0\u1eddi l\u1edbn<\/h4>\n<p>Li\u1ec1u kh\u1edfi \u0111\u1ea7u: 62,5 mg x 2 l\u1ea7n\/ng\u00e0y trong 4 tu\u1ea7n \u0111\u1ea7u.<\/p>\n<p>Li\u1ec1u duy tr\u00ec: T\u0103ng l\u00ean 125 mg x 2 l\u1ea7n\/ng\u00e0y n\u1ebfu dung n\u1ea1p t\u1ed1t.<\/p>\n<h4>Tr\u1ebb em t\u1eeb 1 tu\u1ed5i tr\u1edf l\u00ean b\u1ecb PAH<\/h4>\n<p>Li\u1ec1u kh\u1edfi \u0111\u1ea7u v\u00e0 duy tr\u00ec: 2 mg\/kg x 2 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>Kh\u00f4ng khuy\u1ebfn c\u00e1o t\u0103ng li\u1ec1u ho\u1eb7c t\u0103ng t\u1ea7n su\u1ea5t v\u00ec kh\u00f4ng l\u00e0m t\u0103ng hi\u1ec7u qu\u1ea3 \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng Ravenell 125 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Ravenell 125 kh\u00f4ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau<\/p>\n<ul>\n<li>Qu\u00e1 m\u1eabn v\u1edbi ho\u1ea1t ch\u1ea5t Bosentan ho\u1eb7c b\u1ea5t k\u1ef3 t\u00e1 d\u01b0\u1ee3c n\u00e0o c\u1ee7a thu\u1ed1c.<\/li>\n<li>Suy gan m\u1ee9c \u0111\u1ed9 v\u1eeba v\u00e0 n\u1eb7ng (Child-Pugh B ho\u1eb7c C).<\/li>\n<li>Ph\u1ee5 n\u1eef mang thai ho\u1eb7c c\u00f3 kh\u1ea3 n\u0103ng mang thai m\u00e0 kh\u00f4ng s\u1eed d\u1ee5ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai an to\u00e0n.<\/li>\n<li>D\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi thu\u1ed1c \u1ee9c ch\u1ebf calcineurin Cyclosporin A.<\/li>\n<li>T\u0103ng men gan (AST, ALT) g\u1ea5p 3 l\u1ea7n gi\u1edbi h\u1ea1n b\u00ecnh th\u01b0\u1eddng tr\u1edf l\u00ean.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<p>Kh\u00f4ng c\u00f3 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a Ravenell 125 cho tr\u1ebb s\u01a1 sinh ho\u1eb7c b\u1ec7nh nh\u00e2n d\u01b0\u1edbi 1 tu\u1ed5i, do ch\u01b0a c\u00f3 d\u1eef li\u1ec7u an to\u00e0n \u0111\u1ea7y \u0111\u1ee7.<\/p>\n<p>Bosentan c\u00f3 th\u1ec3 g\u00e2y t\u0103ng men gan ph\u1ee5 thu\u1ed9c li\u1ec1u. Do \u0111\u00f3, c\u1ea7n x\u00e9t nghi\u1ec7m men gan (ALT, AST) tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb, sau khi t\u0103ng li\u1ec1u v\u00e0 h\u00e0ng th\u00e1ng trong su\u1ed1t qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>C\u00f3 th\u1ec3 x\u1ea3y ra t\u00ecnh tr\u1ea1ng gi\u1ea3m hemoglobin, \u0111\u1eb7c bi\u1ec7t trong 4 th\u00e1ng \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb. B\u1ec7nh nh\u00e2n c\u1ea7n l\u00e0m x\u00e9t nghi\u1ec7m m\u00e1u h\u00e0ng th\u00e1ng trong giai \u0111o\u1ea1n \u0111\u1ea7u v\u00e0 m\u1ed7i 3 th\u00e1ng sau \u0111\u00f3.<\/p>\n<p>M\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 b\u1ecb gi\u1eef n\u01b0\u1edbc, g\u00e2y ph\u00f9 ho\u1eb7c t\u0103ng c\u00e2n nhanh. C\u1ea7n theo d\u00f5i v\u00e0 \u0111i\u1ec1u ch\u1ec9nh thu\u1ed1c l\u1ee3i ti\u1ec3u n\u1ebfu c\u1ea7n thi\u1ebft, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n suy tim.<\/p>\n<p>C\u1ea7n ng\u1eebng thu\u1ed1c ngay n\u1ebfu c\u00f3 d\u1ea5u hi\u1ec7u nghi ng\u1edd t\u1ed5n th\u01b0\u01a1ng gan nh\u01b0: v\u00e0ng da, \u0111au h\u1ea1 s\u01b0\u1eddn ph\u1ea3i, m\u1ec7t m\u1ecfi k\u00e9o d\u00e0i.<\/p>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>Ravenell 125 c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5, t\u1eeb nh\u1eb9 \u0111\u1ebfn nghi\u00eam tr\u1ecdng:<\/p>\n<ul>\n<li>R\u1ea5t th\u01b0\u1eddng g\u1eb7p: \u0110au \u0111\u1ea7u, ph\u00f9 (ch\u00e2n, m\u1eb7t), gi\u1eef n\u01b0\u1edbc.<\/li>\n<li>Th\u01b0\u1eddng g\u1eb7p: Thi\u1ebfu m\u00e1u, gi\u1ea3m hemoglobin, ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng, t\u1ee5t huy\u1ebft \u00e1p, \u0111au ng\u1ef1c, ti\u00eau ch\u1ea3y, ch\u00f3ng m\u1eb7t, ngh\u1eb9t m\u0169i, ph\u00e1t ban<\/li>\n<li>\u00cdt g\u1eb7p: Gi\u1ea3m ti\u1ec3u c\u1ea7u, gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh, t\u0103ng men gan k\u00e8m vi\u00eam gan, v\u00e0ng da, vi\u00eam gan m\u1ea1n.<\/li>\n<li>Hi\u1ebfm g\u1eb7p: S\u1ed1c ph\u1ea3n v\u1ec7, ho\u1ea1i t\u1eed gan\/ suy gan, ph\u1ea3n \u1ee9ng ph\u00f9 m\u1ea1ch.<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>Bosentan l\u00e0 ch\u1ea5t c\u1ea3m \u1ee9ng enzym CYP2C9 v\u00e0 CYP3A4 n\u00ean c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn n\u1ed3ng \u0111\u1ed9 c\u1ee7a nhi\u1ec1u thu\u1ed1c kh\u00e1c:<\/p>\n<ul>\n<li>T\u01b0\u01a1ng t\u00e1c nghi\u00eam tr\u1ecdng \u2013 kh\u00f4ng d\u00f9ng chung: Cyclosporin A, rifampicin, fluconazole, glibenclamide, thu\u1ed1c tr\u00e1nh thai n\u1ed9i ti\u1ebft \u0111\u01a1n \u0111\u1ed9c.<\/li>\n<li>T\u01b0\u01a1ng t\u00e1c c\u1ea7n th\u1eadn tr\u1ecdng: Tacrolimus, sirolimus, warfarin, digoxin, lopinavir\/ritonavir, simvastatin, thu\u1ed1c kh\u00e1ng retrovirus (nevirapin&#8230;).<\/li>\n<li>Thu\u1ed1c tr\u00e1nh thai: Bosentan l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 c\u1ee7a thu\u1ed1c tr\u00e1nh thai n\u1ed9i ti\u1ebft, v\u00ec v\u1eady c\u1ea7n k\u1ebft h\u1ee3p v\u1edbi ph\u01b0\u01a1ng ph\u00e1p tr\u00e1nh thai c\u01a1 h\u1ecdc nh\u01b0 bao cao su.<\/li>\n<\/ul>\n<p>Th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 t\u1ea5t c\u1ea3 c\u00e1c thu\u1ed1c \u0111ang s\u1eed d\u1ee5ng, bao g\u1ed3m thu\u1ed1c kh\u00f4ng k\u00ea \u0111\u01a1n, th\u1ea3o d\u01b0\u1ee3c v\u00e0 th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng \u0111\u1ec3 tr\u00e1nh t\u01b0\u01a1ng t\u00e1c b\u1ea5t l\u1ee3i.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Ravenell kh\u00f4ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong th\u1eddi k\u1ef3 mang thai do nguy c\u01a1 g\u00e2y qu\u00e1i thai \u0111\u00e3 \u0111\u01b0\u1ee3c ghi nh\u1eadn trong nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt. Ph\u1ee5 n\u1eef trong \u0111\u1ed9 tu\u1ed5i sinh s\u1ea3n c\u1ea7n \u0111\u01b0\u1ee3c th\u1eed thai \u00e2m t\u00ednh tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u00e0 \u00e1p d\u1ee5ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai \u0111\u00e1ng tin c\u1eady trong su\u1ed1t th\u1eddi gian s\u1eed d\u1ee5ng thu\u1ed1c.<\/p>\n<p>Thu\u1ed1c tr\u00e1nh thai n\u1ed9i ti\u1ebft kh\u00f4ng n\u00ean l\u00e0 ph\u01b0\u01a1ng ph\u00e1p duy nh\u1ea5t khi \u0111ang d\u00f9ng Bosentan do t\u01b0\u01a1ng t\u00e1c l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3. C\u1ea7n k\u1ebft h\u1ee3p th\u00eam c\u00e1c bi\u1ec7n ph\u00e1p v\u1eadt l\u00fd nh\u01b0 bao cao su ho\u1eb7c \u0111\u1eb7t v\u00f2ng.<\/p>\n<p>\u0110\u1ed1i v\u1edbi ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa, ch\u01b0a c\u00f3 d\u1eef li\u1ec7u v\u1ec1 vi\u1ec7c Bosentan c\u00f3 b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9 hay kh\u00f4ng, v\u00ec v\u1eady c\u1ea7n ng\u1eebng cho con b\u00fa n\u1ebfu \u0111i\u1ec1u tr\u1ecb l\u00e0 c\u1ea7n thi\u1ebft.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>D\u00f9 ch\u01b0a ghi nh\u1eadn \u1ea3nh h\u01b0\u1edfng r\u00f5 r\u1ec7t \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c, m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 b\u1ecb h\u1ea1 huy\u1ebft \u00e1p, ch\u00f3ng m\u1eb7t ho\u1eb7c ng\u1ea5t trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb. C\u1ea7n th\u1eadn tr\u1ecdng, \u0111\u1eb7c bi\u1ec7t trong giai \u0111o\u1ea1n \u0111\u1ea7u ho\u1eb7c khi m\u1edbi t\u0103ng li\u1ec1u.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Tr\u01b0\u1eddng h\u1ee3p d\u00f9ng qu\u00e1 li\u1ec1u Bosentan (v\u00ed d\u1ee5 l\u00ean \u0111\u1ebfn 10.000 mg \u1edf thi\u1ebfu ni\u00ean) c\u00f3 th\u1ec3 g\u00e2y t\u1ee5t huy\u1ebft \u00e1p, bu\u1ed3n n\u00f4n, n\u00f4n, ch\u00f3ng m\u1eb7t v\u00e0 nh\u00ecn m\u1edd. \u0110i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng h\u1ed7 tr\u1ee3 l\u00e0 ch\u00ednh, bao g\u1ed3m theo d\u00f5i huy\u1ebft \u00e1p, truy\u1ec1n d\u1ecbch ho\u1eb7c d\u00f9ng thu\u1ed1c n\u00e2ng huy\u1ebft \u00e1p n\u1ebfu c\u1ea7n.<\/p>\n<p>Bosentan kh\u00f4ng \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf hi\u1ec7u qu\u1ea3 b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p l\u1ecdc m\u00e1u, do \u0111\u00f3 kh\u00f4ng \u00e1p d\u1ee5ng bi\u1ec7n ph\u00e1p n\u00e0y trong x\u1eed tr\u00ed qu\u00e1 li\u1ec1u.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<p>B\u1ea3o qu\u1ea3n thu\u1ed1c \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t, tr\u00e1nh \u00e1nh s\u00e1ng v\u00e0 nhi\u1ec7t \u0111\u1ed9 kh\u00f4ng v\u01b0\u1ee3t qu\u00e1 30\u00b0C.<\/p>\n<h2>Thu\u1ed1c Ravenell-125 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 mang \u0111\u01a1n thu\u1ed1c \u0111\u1ebfn c\u00e1c \u0111\u1ecba ch\u1ec9 kinh doanh d\u01b0\u1ee3c ph\u1ea9m tr\u00ean to\u00e0n qu\u1ed1c \u0111\u1ec3 mua \u0111\u01b0\u1ee3c Ravenell 125. Qu\u00fd kh\u00e1ch h\u00e0ng n\u00ean t\u00ecm hi\u1ec3u v\u00e0 l\u1ef1a ch\u1ecdn c\u00e1c \u0111\u1ecba \u0111i\u1ec3m uy t\u00edn \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o mua \u0111\u01b0\u1ee3c thu\u1ed1c an to\u00e0n, ch\u1ea5t l\u01b0\u1ee3ng, c\u00f3 ngu\u1ed3n g\u1ed1c r\u00f5 r\u00e0ng.<\/p>\n<p>Qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o th\u00eam c\u00e1c thu\u1ed1c (s\u1ea3n ph\u1ea9m) kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng nh\u01b0:<\/p>\n<ul>\n<li><a href=\"https:\/\/vnras.com\/drug\/tracleer-125mg\/\">Thu\u1ed1c Tracleer 125mg<\/a> ch\u1ee9a Bosentan gi\u00fap gi\u1ea3m g\u00e1nh n\u1eb7ng l\u00ean tim v\u00e0 c\u1ea3i thi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng nh\u01b0 kh\u00f3 th\u1edf, m\u1ec7t m\u1ecfi. Thu\u1ed1c \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Patheon Inc. (CS xu\u1ea5t x\u01b0\u1edfng: Actelion Pharmaceuticals Ltd) &#8211; Canada.<\/li>\n<\/ul>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<ol>\n<li>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c do nh\u00e0 s\u1ea3n xu\u1ea5t cung c\u1ea5p. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Huong-dan-su-dung-Ravenell-125-vnras.pdf\">t\u1ea1i \u0111\u00e2y<\/a>.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Ravenell 125 ch\u1ee9a ho\u1ea1t ch\u1ea5t Bosentan, \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong \u0111i\u1ec1u tr\u1ecb t\u0103ng \u00e1p l\u1ef1c \u0111\u1ed9ng m\u1ea1ch ph\u1ed5i \u0111\u1ed9 II ho\u1eb7c III, t\u0103ng \u00e1p l\u1ef1c \u0111\u1ed9ng m\u1ea1ch ph\u1ed5i do x\u01a1 c\u1ee9ng b\u00ec to\u00e0n th\u1ec3.<\/p>\n","protected":false},"author":1,"featured_media":123810,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-123792","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/123792","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=123792"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/123810"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=123792"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=123792"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=123792"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}