{"id":123553,"date":"2025-06-15T23:48:43","date_gmt":"2025-06-15T16:48:43","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=123553"},"modified":"2025-07-24T11:48:18","modified_gmt":"2025-07-24T04:48:18","slug":"rixathon-100mg-10ml","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/rixathon-100mg-10ml\/","title":{"rendered":"Rixathon 100mg\/10ml"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Rixathon 100mg\/10ml \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Lek Pharmaceuticals d.d c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 383410647024 (S\u0110K c\u0169: SP3-1231-21)<\/strong><\/p>\n<h2>Rixathon 100mg\/10ml l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i 10 ml Rixathon 100mg\/10ml c\u00f3 ch\u1ee9a: Rituximab 100mg<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Dung d\u1ecbch \u0111\u1eadm \u0111\u1eb7c \u0111\u1ec3 pha dung d\u1ecbch ti\u00eam truy\u1ec1n<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 383410647024 (S\u0110K c\u0169: SP3-1231-21)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 2 l\u1ecd x 10ml<\/p>\n<p>Xu\u1ea5t x\u1ee9: Slovenia<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Rixathon 100mg\/10ml<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Rixathon l\u00e0 m\u1ed9t lo\u1ea1i thu\u1ed1c ch\u1ee9a rituximab, m\u1ed9t kh\u00e1ng th\u1ec3 \u0111\u01a1n d\u00f2ng t\u00e1c d\u1ee5ng l\u00ean t\u1ebf b\u00e0o B, v\u1edbi kh\u1ea3 n\u0103ng li\u00ean k\u1ebft v\u00e0 \u1ee9c ch\u1ebf t\u1ebf b\u00e0o B qua c\u01a1 ch\u1ebf k\u00edch ho\u1ea1t h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch. Rituximab li\u00ean k\u1ebft v\u1edbi kh\u00e1ng nguy\u00ean CD20 tr\u00ean b\u1ec1 m\u1eb7t t\u1ebf b\u00e0o B, l\u00e0m t\u0103ng c\u01b0\u1eddng s\u1ef1 ti\u00eau di\u1ec7t t\u1ebf b\u00e0o B qua qu\u00e1 tr\u00ecnh opsonization v\u00e0 k\u00edch ho\u1ea1t b\u1ed5 th\u1ec3, d\u1eabn \u0111\u1ebfn s\u1ef1 ti\u00eau di\u1ec7t t\u1ebf b\u00e0o B. Rituximab c\u0169ng c\u00f3 th\u1ec3 gi\u00fap gi\u1ea3m c\u00e1c t\u1ebf b\u00e0o B g\u00e2y b\u1ec7nh trong c\u00e1c b\u1ec7nh l\u00fd \u00e1c t\u00ednh v\u00e0 t\u1ef1 mi\u1ec5n.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a Rituximab \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u d\u1ef1a tr\u00ean m\u1ee9c lli\u1ec1u v\u00e0 b\u1ec7nh c\u1ea7n \u0111i\u1ec1u tr\u1ecb kh\u00e1c nhau.<\/p>\n<ul>\n<li>V\u1edbi u lympho kh\u00f4ng Hodgkin: Gi\u00e1 tr\u1ecb trung v\u1ecb th\u1eddi gian b\u00e1n th\u1ea3i pha cu\u1ed1i c\u1ee7a rituximab \u01b0\u1edbc t\u00ednh l\u00e0 22 ng\u00e0y. Theo WHO, c\u00e1c \u0111\u1eb7c \u0111i\u1ec3m thu\u1ed9c v\u1ec1 b\u1ec7nh nh\u00e2n nh\u01b0 tu\u1ed5i, gi\u1edbi t\u00ednh, ch\u1ee7ng t\u1ed9c, s\u1ef1 ho\u1ea1t \u0111\u1ed9ng c\u1ee7a c\u01a1 th\u1ec3 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a rituximab.<\/li>\n<li>V\u1edbi b\u1ea1ch c\u1ea7u lympho m\u1ea1n t\u00ednh: n\u1ebfu \u0111i\u1ec1u tr\u1ecb v\u1edbi li\u1ec1u \u0111\u1ea7u ti\u00ean l\u00e0 375 mg\/m\u00b2 sau \u0111\u00f3 nh\u1eefng chu k\u1ef3 ti\u1ebfp theo (5 chu k\u1ef3) t\u0103ng l\u00ean 500mg\/m\u00b2, gi\u00e1 tr\u1ecb trung b\u00ecnh Cmax l\u00e0 408 mcg\/ml<\/li>\n<li>V\u1edbi b\u1ec7nh vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p: Gi\u00e1 tr\u1ecb trung b\u00ecnh th\u1eddi gian b\u00e1n th\u1ea3i pha cu\u1ed1i sau khi d\u00f9ng li\u1ec1u 1000mg m\u1ed7i 2 tu\u1ea7n c\u1ee7a rituximab \u01b0\u1edbc t\u00ednh l\u00e0 20,8 ng\u00e0y, v\u1edbi gi\u00e1 tr\u1ecb trung b\u00ecnh \u0111\u1ed9 thanh th\u1ea3i to\u00e0n th\u00e2n l\u00e0 0,231\/ng\u00e0y v\u00e0 Vd = 4,6L. C\u00e1c gi\u00e1 tr\u1ecb n\u00e0y c\u0169ng \u0111\u01b0\u1ee3c t\u00ednh to\u00e1n khi th\u1eed v\u1edbi c\u00e1c m\u1ee9c li\u1ec1u kh\u00e1c<\/li>\n<li>V\u1edbi u h\u1ea1t k\u00e8m vi\u00eam \u0111a m\u1ea1ch: Gi\u00e1 tr\u1ecb trung b\u00ecnh th\u1eddi gian b\u00e1n th\u1ea3i \u01b0\u1edbc t\u00ednh l\u00e0 23 ng\u00e0y khi d\u00f9ng li\u1ec1u 375 mg\/m\u00b2\/l\u1ea7n\/tu\u1ea7n x 4 l\u1ea7n, v\u00e0 \u0111\u1ed9 thanh th\u1ea3i l\u00e0 313 l\u00edt \/ ng\u00e0y; th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 Vd=4,50L<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Rixathon 100mg\/10ml \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p><em><strong>1. Ung th\u01b0 h\u1ea1ch kh\u00f4ng Hodgkin (NHL):<\/strong><\/em><\/p>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n ng\u01b0\u1eddi l\u1edbn b\u1ecb ung th\u01b0 h\u1ea1ch nang giai \u0111o\u1ea1n III-IV ch\u01b0a \u0111i\u1ec1u tr\u1ecb, k\u1ebft h\u1ee3p v\u1edbi h\u00f3a tr\u1ecb.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb duy tr\u00ec cho b\u1ec7nh nh\u00e2n ng\u01b0\u1eddi l\u1edbn b\u1ecb ung th\u01b0 h\u1ea1ch nang \u0111\u00e1p \u1ee9ng v\u1edbi \u0111i\u1ec1u tr\u1ecb kh\u1edfi \u0111\u1ea7u.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb \u0111\u01a1n \u0111\u1ed9c cho b\u1ec7nh nh\u00e2n ng\u01b0\u1eddi l\u1edbn b\u1ecb ung th\u01b0 h\u1ea1ch nang giai \u0111o\u1ea1n III-IV kh\u00e1ng h\u00f3a tr\u1ecb ho\u1eb7c t\u00e1i ph\u00e1t l\u1ea7n 2 ho\u1eb7c c\u00e1c l\u1ea7n t\u00e1i ph\u00e1t sau h\u00f3a tr\u1ecb.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n ng\u01b0\u1eddi l\u1edbn b\u1ecb ung th\u01b0 h\u1ea1ch t\u1ebf b\u00e0o l\u1edbn B kh\u00f4ng Hodgkin d\u01b0\u01a1ng t\u00ednh v\u1edbi CD20 k\u1ebft h\u1ee3p v\u1edbi h\u00f3a tr\u1ecb CHOP (cyclophosphamide, doxorubicin, vincristine, prednisolone).<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n tr\u1ebb em (t\u1eeb \u2265 6 th\u00e1ng \u0111\u1ebfn &lt; 18 tu\u1ed5i) b\u1ecb ung th\u01b0 h\u1ea1ch t\u1ebf b\u00e0o l\u1edbn B d\u01b0\u01a1ng t\u00ednh v\u1edbi CD20 ch\u01b0a \u0111i\u1ec1u tr\u1ecb, k\u1ebft h\u1ee3p v\u1edbi h\u00f3a tr\u1ecb.<\/li>\n<\/ul>\n<p><em><strong>2. B\u1ec7nh b\u1ea1ch c\u1ea7u lympho m\u00e3n t\u00ednh (CLL):<\/strong><\/em><\/p>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n b\u1ecb b\u1ea1ch c\u1ea7u lympho m\u00e3n t\u00ednh ch\u01b0a \u0111i\u1ec1u tr\u1ecb ho\u1eb7c t\u00e1i ph\u00e1t\/kh\u00e1ng tr\u1ecb, k\u1ebft h\u1ee3p v\u1edbi h\u00f3a tr\u1ecb.<\/li>\n<li>C\u1ea7n l\u01b0u \u00fd l\u00e0 ch\u1ec9 c\u00f3 \u00edt d\u1eef li\u1ec7u v\u1ec1 t\u00ednh hi\u1ec7u qu\u1ea3 v\u00e0 an to\u00e0n c\u1ee7a thu\u1ed1c tr\u00ean b\u1ec7nh nh\u00e2n \u0111\u00e3 t\u1eebng \u0111i\u1ec1u tr\u1ecb v\u1edbi c\u00e1c kh\u00e1ng th\u1ec3 \u0111\u01a1n d\u00f2ng, bao g\u1ed3m rituximab.<\/li>\n<\/ul>\n<p><em><strong>3. Vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p (Rheumatoid arthritis):<\/strong><\/em><\/p>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n ng\u01b0\u1eddi l\u1edbn c\u00f3 vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p ho\u1ea1t \u0111\u1ed9ng nghi\u00eam tr\u1ecdng, kh\u00f4ng \u0111\u00e1p \u1ee9ng ho\u1eb7c kh\u00f4ng dung n\u1ea1p v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00f4ng steroid (DMARD) bao g\u1ed3m c\u00e1c li\u1ec7u ph\u00e1p \u1ee9c ch\u1ebf y\u1ebfu t\u1ed1 ho\u1ea1i t\u1eed kh\u1ed1i u (TNF)<\/li>\n<\/ul>\n<p><em><strong>4. Vi\u00eam m\u1ea1ch polyangiitis v\u00e0 vi\u00eam m\u1ea1ch vi th\u1ec3 (Granulomatosis with polyangiitis \u2013 GPA, v\u00e0 Microscopic polyangiitis \u2013 MPA):<\/strong><\/em><\/p>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n ng\u01b0\u1eddi l\u1edbn c\u00f3 vi\u00eam m\u1ea1ch polyangiitis ho\u1ea1t \u0111\u1ed9ng nghi\u00eam tr\u1ecdng k\u1ebft h\u1ee3p v\u1edbi corticosteroid.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n tr\u1ebb em (t\u1eeb \u2265 2 tu\u1ed5i \u0111\u1ebfn &lt; 18 tu\u1ed5i) c\u00f3 vi\u00eam m\u1ea1ch polyangiitis ho\u1eb7c vi\u00eam m\u1ea1ch vi th\u1ec3 ho\u1ea1t \u0111\u1ed9ng nghi\u00eam tr\u1ecdng.<\/li>\n<\/ul>\n<p><em><strong>5. Pemphigus vulgaris:<\/strong><\/em><\/p>\n<p>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n m\u1eafc pemphigus vulgaris m\u1ee9c \u0111\u1ed9 v\u1eeba v\u00e0 n\u1eb7ng.<\/p>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p><strong>Li\u1ec1u d\u00f9ng cho ng\u01b0\u1eddi l\u1edbn<\/strong><\/p>\n<p><em><strong>1. Ung th\u01b0 h\u1ea1ch kh\u00f4ng Hodgkin (NHL):<\/strong><\/em><\/p>\n<p>\u0110i\u1ec1u tr\u1ecb k\u1ebft h\u1ee3p v\u1edbi h\u00f3a tr\u1ecb li\u1ec7u: Li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 375 mg\/m\u00b2 di\u1ec7n t\u00edch b\u1ec1 m\u1eb7t c\u01a1 th\u1ec3, ti\u00eam t\u0129nh m\u1ea1ch v\u00e0o ng\u00e0y 1 c\u1ee7a m\u1ed7i chu k\u1ef3 h\u00f3a tr\u1ecb trong t\u1ed1i \u0111a 8 chu k\u1ef3.<\/p>\n<p>Li\u1ec7u ph\u00e1p duy tr\u00ec: \u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n \u0111\u00e3 \u0111i\u1ec1u tr\u1ecb th\u00e0nh c\u00f4ng b\u1eb1ng h\u00f3a tr\u1ecb li\u1ec7u v\u00e0 c\u00f3 ph\u1ea3n \u1ee9ng t\u00edch c\u1ef1c, li\u1ec1u l\u00e0 375 mg\/m\u00b2 di\u1ec7n t\u00edch b\u1ec1 m\u1eb7t c\u01a1 th\u1ec3 m\u1ed7i 2 th\u00e1ng trong t\u1ed1i \u0111a 2 n\u0103m (t\u1ed1i \u0111a 12 l\u1ea7n ti\u00eam).<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb b\u1eb1ng monotherapy cho b\u1ec7nh nh\u00e2n t\u00e1i ph\u00e1t: Li\u1ec1u l\u00e0 375 mg\/m\u00b2 di\u1ec7n t\u00edch b\u1ec1 m\u1eb7t c\u01a1 th\u1ec3, ti\u00eam t\u0129nh m\u1ea1ch m\u1ed7i tu\u1ea7n m\u1ed9t l\u1ea7n trong 4 tu\u1ea7n.<\/p>\n<p><em><strong>2. L\u01a1-x\u00ea-mi t\u1ebf b\u00e0o B (CLL):<\/strong><\/em><\/p>\n<p>\u0110i\u1ec1u tr\u1ecb k\u1ebft h\u1ee3p v\u1edbi h\u00f3a tr\u1ecb: 375 mg\/m\u00b2 di\u1ec7n t\u00edch b\u1ec1 m\u1eb7t c\u01a1 th\u1ec3 v\u00e0o ng\u00e0y \u0111\u1ea7u ti\u00ean c\u1ee7a chu k\u1ef3 \u0111\u1ea7u ti\u00ean, sau \u0111\u00f3 500 mg\/m\u00b2 di\u1ec7n t\u00edch b\u1ec1 m\u1eb7t c\u01a1 th\u1ec3 v\u00e0o ng\u00e0y ti\u1ebfp theo c\u1ee7a c\u00e1c chu k\u1ef3 sau trong t\u1ed5ng c\u1ed9ng 6 chu k\u1ef3.<\/p>\n<p><em><strong>3. Vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p (RA):<\/strong><\/em><\/p>\n<p>\u0110i\u1ec1u tr\u1ecb k\u1ebft h\u1ee3p v\u1edbi methotrexate: Li\u1ec1u d\u00f9ng l\u00e0 1,000 mg ti\u00eam t\u0129nh m\u1ea1ch, ti\u1ebfp theo l\u00e0 m\u1ed9t li\u1ec1u th\u1ee9 hai sau 2 tu\u1ea7n.<\/p>\n<p><em><strong>4. Vi\u00eam m\u1ea1ch d\u1ecb \u1ee9ng v\u00e0 vi\u00eam m\u1ea1ch vi th\u1ec3:<\/strong><\/em><\/p>\n<p>\u0110i\u1ec1u tr\u1ecb kh\u1edfi \u0111\u1ea7u: 375 mg\/m\u00b2 di\u1ec7n t\u00edch b\u1ec1 m\u1eb7t c\u01a1 th\u1ec3, ti\u00eam t\u0129nh m\u1ea1ch m\u1ed7i tu\u1ea7n m\u1ed9t l\u1ea7n trong 4 tu\u1ea7n.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb duy tr\u00ec: Sau 16 tu\u1ea7n, duy tr\u00ec li\u1ec1u 500 mg ti\u00eam t\u0129nh m\u1ea1ch m\u1ed7i 6 th\u00e1ng trong t\u1ed1i thi\u1ec3u 2 n\u0103m.<\/p>\n<p><em><strong>5. Pemphigus vulgaris:<\/strong><\/em><\/p>\n<ul>\n<li>\u0110i\u1ec1u tr\u1ecb kh\u1edfi \u0111\u1ea7u: 1000 mg ti\u00eam t\u0129nh m\u1ea1ch, ti\u1ebfp theo 1000 mg v\u00e0o hai tu\u1ea7n sau.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb duy tr\u00ec: 500 mg ti\u00eam t\u0129nh m\u1ea1ch m\u1ed7i 6 th\u00e1ng sau 1 n\u0103m v\u00e0 18 th\u00e1ng \u0111i\u1ec1u tr\u1ecb.<\/li>\n<\/ul>\n<p><strong>Li\u1ec1u d\u00f9ng cho tr\u1ebb em (t\u1eeb 6 th\u00e1ng \u0111\u1ebfn d\u01b0\u1edbi 18 tu\u1ed5i):<\/strong><\/p>\n<p><em><strong>1. Ung th\u01b0 h\u1ea1ch kh\u00f4ng Hodgkin:<\/strong><\/em><\/p>\n<p>Li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 375 mg\/m\u00b2 di\u1ec7n t\u00edch b\u1ec1 m\u1eb7t c\u01a1 th\u1ec3, ti\u00eam t\u0129nh m\u1ea1ch k\u1ebft h\u1ee3p v\u1edbi li\u1ec7u ph\u00e1p h\u00f3a tr\u1ecb li\u1ec7u LMB.<\/p>\n<p><em><strong>2. Vi\u00eam m\u1ea1ch d\u1ecb \u1ee9ng v\u00e0 vi\u00eam m\u1ea1ch vi th\u1ec3:<\/strong><\/em><\/p>\n<p>Li\u1ec1u khuy\u1ebfn c\u00e1o l\u00e0 375 mg\/m\u00b2 di\u1ec7n t\u00edch b\u1ec1 m\u1eb7t c\u01a1 th\u1ec3, ti\u00eam t\u0129nh m\u1ea1ch m\u1ed7i tu\u1ea7n m\u1ed9t l\u1ea7n trong 4 tu\u1ea7n.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<ul>\n<li>Rixathon ph\u1ea3i \u0111\u01b0\u1ee3c ti\u00eam t\u0129nh m\u1ea1ch d\u01b0\u1edbi s\u1ef1 gi\u00e1m s\u00e1t ch\u1eb7t ch\u1ebd c\u1ee7a nh\u00e2n vi\u00ean y t\u1ebf c\u00f3 kinh nghi\u1ec7m, trong m\u1ed9t m\u00f4i tr\u01b0\u1eddng c\u00f3 \u0111\u1ea7y \u0111\u1ee7 c\u00e1c thi\u1ebft b\u1ecb c\u1ea5p c\u1ee9u.<\/li>\n<li>Thu\u1ed1c kh\u00f4ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng d\u01b0\u1edbi d\u1ea1ng ti\u00eam tr\u1ef1c ti\u1ebfp hay ti\u00eam bolus. Rixathon ph\u1ea3i \u0111\u01b0\u1ee3c ti\u00eam t\u0129nh m\u1ea1ch qua m\u1ed9t \u0111\u01b0\u1eddng ti\u00eam ri\u00eang bi\u1ec7t.<\/li>\n<li>T\u1ed1c \u0111\u1ed9 ti\u00eam c\u00f3 th\u1ec3 b\u1eaft \u0111\u1ea7u t\u1eeb 50 mg\/gi\u1edd trong 30 ph\u00fat \u0111\u1ea7u ti\u00ean, sau \u0111\u00f3 c\u00f3 th\u1ec3 t\u0103ng t\u1ed1c \u0111\u1ed9 l\u00ean \u0111\u1ebfn 400 mg\/gi\u1edd t\u00f9y thu\u1ed9c v\u00e0o t\u00ecnh tr\u1ea1ng c\u1ee7a b\u1ec7nh nh\u00e2n.<\/li>\n<\/ul>\n<figure id=\"attachment_123554\" aria-describedby=\"caption-attachment-123554\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-123554\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Rixathon-100mg10ml.jpg\" alt=\"Rixathon 100mg\/10ml\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Rixathon-100mg10ml.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Rixathon-100mg10ml-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Rixathon-100mg10ml-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Rixathon-100mg10ml-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-123554\" class=\"wp-caption-text\">Thu\u1ed1c Rixathon 100mg\/10ml ch\u1ee9a ho\u1ea1t ch\u1ea5t ch\u00ednh l\u00e0 Rituximab d\u00f9ng \u0111i\u1ec1u tr\u1ecb trong c\u00e1c b\u1ec7nh vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p, u lym pho, Pemphigus vulgaris, u h\u1ea1ch,&#8230;<\/figcaption><\/figure>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Rixathon 100mg\/10ml trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<p>Kh\u00f4ng d\u00f9ng <strong><em>dung d\u1ecbch pha ti\u00eam truy\u1ec1n Rixathon<\/em> 100mg\/10ml<\/strong> trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p sau:<\/p>\n<ul>\n<li>D\u1ecb \u1ee9ng v\u1edbi Rituximab.c\u00f3 trong d<strong>ung d\u1ecbch Rixathon 100mg\/10ml<\/strong><\/li>\n<li>Nhi\u1ec5m tr\u00f9ng nghi\u00eam tr\u1ecdng ho\u1eb7c \u0111ang ho\u1ea1t \u0111\u1ed9ng.<\/li>\n<li>T\u00ecnh tr\u1ea1ng mi\u1ec5n d\u1ecbch nghi\u00eam tr\u1ecdng, nh\u01b0 suy gi\u1ea3m mi\u1ec5n d\u1ecbch n\u1eb7ng.<\/li>\n<li>B\u1ec7nh tim nghi\u00eam tr\u1ecdng (nh\u01b0 suy tim giai \u0111o\u1ea1n cu\u1ed1i ho\u1eb7c b\u1ec7nh tim ch\u01b0a ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c).<\/li>\n<li>Tr\u1ebb em d\u01b0\u1edbi 2 tu\u1ed5i \u0111\u1ed1i v\u1edbi b\u1ec7nh vi\u00eam m\u1ea1ch d\u1ecb \u1ee9ng v\u00e0 vi\u00eam m\u1ea1ch vi th\u1ec3 do kh\u00f4ng \u0111\u1ee7 b\u1eb1ng ch\u1ee9ng v\u1ec1 hi\u1ec7u qu\u1ea3 v\u00e0 an to\u00e0n.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Tr\u01b0\u1edbc m\u1ed7i l\u1ea7n ti\u00eam, c\u1ea7n th\u1ef1c hi\u1ec7n ti\u1ec1n thu\u1ed1c (premedication) g\u1ed3m thu\u1ed1c gi\u1ea3m s\u1ed1t v\u00e0 kh\u00e1ng histamine (paracetamol v\u00e0 diphenhydramine) \u0111\u1ec3 gi\u1ea3m thi\u1ec3u c\u00e1c ph\u1ea3n \u1ee9ng li\u00ean quan \u0111\u1ebfn ti\u00eam.<\/li>\n<li>N\u1ebfu b\u1ec7nh nh\u00e2n b\u1ecb ung th\u01b0 h\u1ea1ch kh\u00f4ng Hodgkin ho\u1eb7c b\u1ec7nh b\u1ea1ch c\u1ea7u lympho m\u1ea1n t\u00ednh, c\u1ea7n xem x\u00e9t ti\u1ec1n thu\u1ed1c v\u1edbi glucocorticoid n\u1ebfu Rixathon kh\u00f4ng \u0111\u01b0\u1ee3c ti\u00eam k\u1ebft h\u1ee3p v\u1edbi h\u00f3a tr\u1ecb c\u00f3 ch\u1ee9a glucocorticoid.<\/li>\n<li>C\u1ea7n theo d\u00f5i c\u00e1c ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7 trong su\u1ed1t qu\u00e1 tr\u00ecnh ti\u00eam thu\u1ed1c v\u00e0 ng\u1eebng ti\u00eam n\u1ebfu ph\u00e1t hi\u1ec7n c\u00e1c tri\u1ec7u ch\u1ee9ng nghi\u00eam tr\u1ecdng.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n c\u1ee7a Rixathon 100mg\/10ml tr\u00ean m\u1ed9t s\u1ed1 h\u1ec7 c\u01a1 quan c\u00f3 th\u1ec3 k\u1ec3 \u0111\u1ebfn nh\u01b0:<\/p>\n<ul>\n<li>M\u00e1u v\u00e0 h\u1ea1ch b\u1ea1ch huy\u1ebft: gi\u1ea3m b\u1ea1ch c\u1ea7u, ti\u1ec3u c\u1ea7u; r\u1ed1i lo\u1ea1n \u0111\u00f4ng m\u00e1u; thi\u1ebfu m\u00e1u;&#8230;<\/li>\n<li>Nhi\u1ec5m tr\u00f9ng: nhi\u1ec5m virus, nhi\u1ec5m khu\u1ea9n, nhi\u1ec5m n\u1ea5m<\/li>\n<li>H\u1ec7 mi\u1ec5n d\u1ecbch: ph\u00f9 m\u1ea1ch, ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7<\/li>\n<li>Chuy\u1ec3n ho\u00e1 v\u00e0 dinh d\u01b0\u1ee1ng: \u0111\u01b0\u1eddng huy\u1ebft t\u0103ng, c\u00e2n n\u1eb7ng gi\u1ea3m,&#8230;<\/li>\n<li>Th\u1ea7n kinh: b\u1ed3n ch\u1ed3n, lo \u00e2u, r\u1ed1i lo\u1ea1n v\u1ecb gi\u00e1c, m\u1ea5t c\u1ea3m gi\u00e1c,&#8230;<\/li>\n<li>Tim v\u00e0 m\u1ea1ch m\u00e1u: lo\u1ea1n nh\u1ecbp tim, rung nh\u0129, \u0111au th\u1eaft ng\u1ef1c, thi\u1ebfu m\u00e1u c\u01a1 tim, t\u0103ng ho\u1eb7c h\u1ea1 huy\u1ebft \u00e1p,&#8230;<\/li>\n<li>H\u00f4 h\u1ea5p: ho, kh\u00f3 th\u1edf, vi\u00eam m\u0169i, \u0111au th\u1eaft ng\u1ef1c, suy h\u00f4 h\u1ea5p,&#8230;<\/li>\n<li>Da: ng\u1ee9a, ph\u00e1t ban, m\u00e0y \u0111ay, h\u1ed9i ch\u1ee9ng Stevens Johnson,&#8230;<\/li>\n<li>C\u01a1-x\u01b0\u01a1ng kh\u1edbp: \u0111au c\u01a1-kh\u1edbp, t\u0103ng tr\u01b0\u01a1ng l\u1ef1c c\u01a1,&#8230;<\/li>\n<li>Ti\u1ebft ni\u1ec7u: suy th\u1eadn<\/li>\n<li>To\u00e0n th\u00e2n v\u00e0 t\u1ea1i ch\u1ed7: s\u1ed1t, \u1edbn l\u1ea1nh, \u0111au t\u1ea1i v\u1ecb tr\u00ed ti\u00eam,&#8230;<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<p>C\u00e1c nghi\u00ean c\u1ee9u v\u1ec1 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c v\u1edbi Rixathon v\u1eabn c\u00f2n h\u1ea1n ch\u1ebf. Trong c\u00e1c b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh b\u1ea1ch c\u1ea7u lympho m\u1ea1n t\u00ednh (CLL), vi\u1ec7c ph\u1ed1i h\u1ee3p rituximab v\u1edbi fludarabine ho\u1eb7c cyclophosphamide kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a t\u1eebng thu\u1ed1c. Ngo\u00e0i ra, s\u1ef1 ph\u1ed1i h\u1ee3p gi\u1eefa methotrexate v\u00e0 rituximab \u1edf b\u1ec7nh nh\u00e2n vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p c\u0169ng kh\u00f4ng l\u00e0m thay \u0111\u1ed5i d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a rituximab.<\/p>\n<p>\u1ede m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n c\u00f3 \u0111\u00e1p \u1ee9ng mi\u1ec5n d\u1ecbch v\u1edbi kh\u00e1ng th\u1ec3 anti-mouse (HAMA) ho\u1eb7c kh\u00e1ng th\u1ec3 \u0111\u1ed1i v\u1edbi thu\u1ed1c (ADA), c\u00f3 th\u1ec3 xu\u1ea5t hi\u1ec7n c\u00e1c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng ho\u1eb7c qu\u00e1 m\u1eabn khi s\u1eed d\u1ee5ng c\u00e1c kh\u00e1ng th\u1ec3 \u0111\u01a1n d\u00f2ng kh\u00e1c. T\u1ec9 l\u1ec7 nhi\u1ec5m tr\u00f9ng trong nh\u1eefng b\u1ec7nh nh\u00e2n \u0111i\u1ec1u tr\u1ecb v\u1edbi rituximab t\u0103ng l\u00ean so v\u1edbi khi s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c DMARD sinh h\u1ecdc kh\u00e1c.<\/p>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Thai k\u1ef3: Rituximab kh\u00f4ng n\u00ean \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong thai k\u1ef3 tr\u1eeb khi l\u1ee3i \u00edch ti\u1ec1m t\u00e0ng v\u01b0\u1ee3t tr\u1ed9i so v\u1edbi nguy c\u01a1 ti\u1ec1m \u1ea9n. Rituximab c\u00f3 th\u1ec3 \u0111i qua h\u00e0ng r\u00e0o nhau thai v\u00e0 g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1c t\u1ebf b\u00e0o B c\u1ee7a thai nhi, d\u1eabn \u0111\u1ebfn s\u1ef1 gi\u1ea3m s\u1ed1 l\u01b0\u1ee3ng t\u1ebf b\u00e0o B v\u00e0 suy gi\u1ea3m mi\u1ec5n d\u1ecbch \u1edf tr\u1ebb s\u01a1 sinh.<\/p>\n<p>Cho con b\u00fa: M\u1eb7c d\u00f9 c\u00f3 r\u1ea5t \u00edt d\u1eef li\u1ec7u v\u1ec1 s\u1ef1 b\u00e0i ti\u1ebft rituximab v\u00e0o s\u1eefa m\u1eb9, nh\u01b0ng n\u1ed3ng \u0111\u1ed9 rituximab trong s\u1eefa m\u1eb9 r\u1ea5t th\u1ea5p (d\u01b0\u1edbi 0.4% li\u1ec1u s\u1eed d\u1ee5ng). Do \u0111\u00f3, kh\u00f4ng khuy\u1ebfn c\u00e1o cho con b\u00fa trong su\u1ed1t qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb v\u1edbi Rixathon v\u00e0 t\u1ed1i thi\u1ec3u 6 th\u00e1ng sau khi \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Kh\u00f4ng c\u00f3 nghi\u00ean c\u1ee9u c\u1ee5 th\u1ec3 n\u00e0o v\u1ec1 t\u00e1c \u0111\u1ed9ng c\u1ee7a Rixathon l\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c. Tuy nhi\u00ean, c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a thu\u1ed1c, bao g\u1ed3m ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn ho\u1eb7c c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n kh\u00e1c, c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c. Do \u0111\u00f3, b\u1ec7nh nh\u00e2n c\u1ea7n th\u1eadn tr\u1ecdng khi th\u1ef1c hi\u1ec7n c\u00e1c c\u00f4ng vi\u1ec7c n\u00e0y trong su\u1ed1t qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Qu\u00e1 li\u1ec1u: C\u00e1c nghi\u00ean c\u1ee9u v\u1ec1 qu\u00e1 li\u1ec1u rituximab v\u1eabn c\u00f2n h\u1ea1n ch\u1ebf. Li\u1ec1u t\u1ed1i \u0111a \u0111\u00e3 \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m tr\u00ean ng\u01b0\u1eddi l\u00e0 5,000 mg (2,250 mg\/m2) trong m\u1ed9t nghi\u00ean c\u1ee9u t\u0103ng li\u1ec1u cho b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh b\u1ea1ch c\u1ea7u lympho m\u1ea1n t\u00ednh, v\u00e0 kh\u00f4ng c\u00f3 d\u1ea5u hi\u1ec7u an to\u00e0n n\u00e0o \u0111\u01b0\u1ee3c ghi nh\u1eadn.<\/p>\n<p>X\u1eed tr\u00ed: N\u1ebfu b\u1ec7nh nh\u00e2n c\u00f3 d\u1ea5u hi\u1ec7u qu\u00e1 li\u1ec1u, c\u1ea7n d\u1eebng ngay vi\u1ec7c truy\u1ec1n thu\u1ed1c v\u00e0 theo d\u00f5i ch\u1eb7t ch\u1ebd t\u00ecnh tr\u1ea1ng s\u1ee9c kh\u1ecfe c\u1ee7a b\u1ec7nh nh\u00e2n. C\u00e1c tri\u1ec7u ch\u1ee9ng qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 bao g\u1ed3m c\u00e1c ph\u1ea3n \u1ee9ng gi\u1ed1ng c\u1ea3m c\u00fam ho\u1eb7c suy h\u00f4 h\u1ea5p, nh\u01b0 \u0111\u00e3 ghi nh\u1eadn \u1edf m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u. Tr\u01b0\u1eddng h\u1ee3p n\u00e0y c\u1ea7n can thi\u1ec7p k\u1ecbp th\u1eddi, t\u00f9y thu\u1ed9c v\u00e0o m\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a tri\u1ec7u ch\u1ee9ng.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<ul>\n<li>Gi\u1eef Rixathon 100mg\/10ml \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t 2\u2103-8\u2103, tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi nh\u01b0ng c\u0169ng kh\u00f4ng \u0111\u1ec3 trong t\u1ee7 l\u1ea1nh ng\u0103n \u0111\u00f4ng.<\/li>\n<li>B\u1ea3o qu\u1ea3n l\u1ecd thu\u1ed1c trong h\u1ed9p ban \u0111\u1ea7u \u0111\u1ec3 kh\u00f4ng ph\u1ea3i ti\u1ebfp x\u00fac v\u1edbi \u00e1nh s\u00e1ng<\/li>\n<li>Sau khi pha Rixathon 100mg\/10ml ph\u1ea3i d\u00f9ng ngay ho\u1eb7c d\u00f9ng trong v\u00f2ng 24h n\u1ebfu b\u1ea3o qu\u1ea3n \u1edf nhi\u1ec7t \u0111\u1ed9 y\u00eau c\u1ea7u ph\u00eda tr\u00ean.<\/li>\n<li>Kh\u00f4ng \u0111\u1ec3 Rixathon 100mg\/10ml trong t\u1ea7m v\u1edbi tr\u1ebb em<\/li>\n<li>Kh\u00f4ng s\u1eed d\u1ee5ng Rixathon 100mg\/10ml khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Rixathon 100mg\/10ml gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Rixathon 100mg\/10ml hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i nhi\u1ec1u nh\u00e0 thu\u1ed1c t\u01b0 nh\u00e2n v\u00e0 nh\u00e0 thu\u1ed1c c\u00f4ng tr\u00ean kh\u1eafp c\u1ea3 n\u01b0\u1edbc, gi\u00e1 thu\u1ed1c Rixathon 100mg\/10ml tham kh\u1ea3o c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. \u0110\u1ec3 hi\u1ec3u h\u01a1n v\u1ec1 thu\u1ed1c, qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>Emer JJ, Claire W (2009). Rituximab: a review of dermatological applications. J Clin Aesthet Dermatol. Truy c\u1eadp ng\u00e0y 15 th\u00e1ng 6 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2924133\/\" rel=\"noopener\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC2924133\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p style=\"text-align: left;\"><span style=\"font-weight: 400;\"><span style=\"color: #d83131;\">CH\u00daNG T\u00d4I KH\u00d4NG KINH DOANH S\u1ea2N PH\u1ea8M, B\u00c0I VI\u1ebeT CH\u1ec8 MANG T\u00cdNH CH\u1ea4T THAM KH\u1ea2O V\u00c0 CUNG C\u1ea4P TH\u00d4NG TIN CHO KH\u00c1CH H\u00c0NG T\u00ccM HI\u1ec2U<\/span><br \/>\nThu\u1ed1c Rixathon 100mg\/10ml ch\u1ee9a ho\u1ea1t ch\u1ea5t ch\u00ednh l\u00e0 Rituximab d\u00f9ng \u0111i\u1ec1u tr\u1ecb trong c\u00e1c b\u1ec7nh vi\u00eam kh\u1edbp d\u1ea1ng th\u1ea5p, u lym pho, <\/span><b>Pemphigus vulgaris, u h\u1ea1ch,&#8230;<\/b><\/p>\n","protected":false},"author":1,"featured_media":123556,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-123553","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/123553","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=123553"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/123556"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=123553"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=123553"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=123553"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}