{"id":123049,"date":"2025-06-12T16:38:04","date_gmt":"2025-06-12T09:38:04","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=123049"},"modified":"2025-07-24T11:48:24","modified_gmt":"2025-07-24T04:48:24","slug":"tegrucil-4","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/tegrucil-4\/","title":{"rendered":"Tegrucil-4"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c Tegrucil-4 \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m \u0110\u1ea1t Vi Ph\u00fa c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 93110664224 (S\u0110K c\u0169: VD-25455-16)<\/strong><\/p>\n<h2>Tegrucil-4 l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ng Tegrucil-4<\/strong> c\u00f3 ch\u1ee9a: Acenocoumarol 4mg<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: 3110664224 (S\u0110K c\u0169: VD-25455-16)<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 6 v\u1ec9 x 10 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Vi\u1ec7t Nam<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 36 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c Tegrucil-4<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<p>Acenocoumarol l\u00e0 thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng \u0111\u01b0\u1eddng u\u1ed1ng thu\u1ed9c nh\u00f3m coumarin, ho\u1ea1t \u0111\u1ed9ng th\u00f4ng qua vi\u1ec7c \u1ee9c ch\u1ebf enzym vitamin K epoxide reductase (VKOR). C\u01a1 ch\u1ebf n\u00e0y l\u00e0m gi\u00e1n \u0111o\u1ea1n qu\u00e1 tr\u00ecnh t\u00e1i sinh vitamin K \u1edf gan, t\u1eeb \u0111\u00f3 l\u00e0m suy gi\u1ea3m kh\u1ea3 n\u0103ng carboxyl h\u00f3a c\u00e1c ti\u1ec1n ch\u1ea5t c\u1ee7a y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u II, VII, IX v\u00e0 X. K\u1ebft qu\u1ea3 l\u00e0 c\u00e1c y\u1ebfu t\u1ed1 n\u00e0y kh\u00f4ng th\u1ec3 ho\u1ea1t h\u00f3a, d\u1eabn t\u1edbi hi\u1ec7u \u1ee9ng ch\u1ed1ng \u0111\u00f4ng gi\u00e1n ti\u1ebfp nh\u01b0ng c\u00f3 hi\u1ec7u l\u1ef1c b\u1ec1n v\u1eefng trong c\u01a1 th\u1ec3.<\/p>\n<h3>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/h3>\n<p>Sau khi u\u1ed1ng, acenocoumarol \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, v\u1edbi sinh kh\u1ea3 d\u1ee5ng kho\u1ea3ng 60%. N\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 1 \u2013 3 gi\u1edd. Thu\u1ed1c li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (~99%) v\u00e0 c\u00f3 th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 t\u1eeb 0,16 \u2013 0,34 l\u00edt\/kg. C\u1ea3 hai \u0111\u1ed3ng ph\u00e2n S(-) v\u00e0 R(+) c\u1ee7a thu\u1ed1c \u0111\u1ec1u tr\u1ea3i qua chuy\u1ec3n h\u00f3a \u1edf gan: \u0111\u1ed3ng ph\u00e2n S ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c CYP2C9 chuy\u1ec3n h\u00f3a, c\u00f2n \u0111\u1ed3ng ph\u00e2n R do c\u00e1c isoenzym kh\u00e1c x\u1eed l\u00fd. Th\u1eddi gian b\u00e1n th\u1ea3i dao \u0111\u1ed9ng t\u1eeb 8 \u0111\u1ebfn 11 gi\u1edd. S\u1ea3n ph\u1ea9m chuy\u1ec3n h\u00f3a \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i ch\u1ee7 y\u1ebfu qua n\u01b0\u1edbc ti\u1ec3u (~60%) v\u00e0 ph\u1ea7n c\u00f2n l\u1ea1i qua ph\u00e2n (~29%).<\/p>\n<h2>Thu\u1ed1c Tegrucil-4 \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p><strong>Vi\u00ean n\u00e9n Tegrucil-4<\/strong> \u0111\u01b0\u1ee3c d\u00f9ng trong c\u00e1c t\u00ecnh hu\u1ed1ng c\u00f3 nguy c\u01a1 ho\u1eb7c bi\u1ebfn ch\u1ee9ng huy\u1ebft kh\u1ed1i, bao g\u1ed3m:<\/p>\n<ul>\n<li>D\u1ef1 ph\u00f2ng huy\u1ebft kh\u1ed1i \u1edf b\u1ec7nh nh\u00e2n tim m\u1ea1ch: rung nh\u0129, van tim nh\u00e2n t\u1ea1o, h\u1eb9p van hai l\u00e1.<\/li>\n<li>Ng\u0103n ng\u1eeba bi\u1ebfn ch\u1ee9ng huy\u1ebft kh\u1ed1i sau nh\u1ed3i m\u00e1u c\u01a1 tim, \u0111\u1eb7c bi\u1ec7t \u1edf b\u1ec7nh nh\u00e2n c\u00f3 huy\u1ebft kh\u1ed1i th\u00e0nh tim, lo\u1ea1n \u0111\u1ed9ng th\u1ea5t tr\u00e1i.<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb v\u00e0 ph\u00f2ng t\u00e1i ph\u00e1t huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch s\u00e2u v\u00e0 thuy\u00ean t\u1eafc ph\u1ed5i, sau \u0111i\u1ec1u tr\u1ecb kh\u1edfi \u0111\u1ea7u v\u1edbi heparin.<\/li>\n<li>D\u1ef1 ph\u00f2ng huy\u1ebft kh\u1ed1i sau ph\u1eabu thu\u1eadt thay kh\u1edbp h\u00e1ng ho\u1eb7c trong c\u00e1c th\u1ee7 thu\u1eadt c\u00f3 nguy c\u01a1.<\/li>\n<li>Ng\u0103n ng\u1eeba huy\u1ebft kh\u1ed1i h\u00ecnh th\u00e0nh trong \u1ed1ng th\u00f4ng n\u1ed9i m\u1ea1ch.<\/li>\n<\/ul>\n<figure id=\"attachment_123060\" aria-describedby=\"caption-attachment-123060\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-123060\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Tegrucil-4.jpg\" alt=\"Tegrucil-4\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Tegrucil-4.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Tegrucil-4-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Tegrucil-4-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/Tegrucil-4-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-123060\" class=\"wp-caption-text\">Thu\u1ed1c Tegrucil-4 l\u00e0 thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u d\u1ea1ng \u0111\u01b0\u1eddng u\u1ed1ng, gi\u00fap ng\u0103n ng\u1eeba huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch v\u00e0 bi\u1ebfn ch\u1ee9ng tim m\u1ea1ch. D\u00f9ng theo ch\u1ec9 \u0111\u1ecbnh v\u00e0 theo d\u00f5i INR \u0111\u1ecbnh k\u1ef3.<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Li\u1ec1u kh\u1edfi \u0111\u1ea7u th\u01b0\u1eddng l\u00e0 4 mg\/ng\u00e0y v\u00e0o ng\u00e0y \u0111\u1ea7u, c\u00f3 th\u1ec3 t\u0103ng l\u00ean 4 \u2013 8 mg v\u00e0o ng\u00e0y ti\u1ebfp theo. Sau \u0111\u00f3, li\u1ec1u duy tr\u00ec th\u01b0\u1eddng dao \u0111\u1ed9ng t\u1eeb 1 \u2013 8 mg\/ng\u00e0y, \u0111i\u1ec1u ch\u1ec9nh theo m\u1ee9c INR mong mu\u1ed1n. Vi\u1ec7c hi\u1ec7u ch\u1ec9nh li\u1ec1u n\u00ean th\u1ef1c hi\u1ec7n t\u1eebng b\u01b0\u1edbc nh\u1ecf (1 mg\/l\u1ea7n).<\/p>\n<p>Ng\u01b0\u1eddi gi\u00e0 th\u01b0\u1eddng nh\u1ea1y c\u1ea3m h\u01a1n v\u1edbi thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng. Do \u0111\u00f3, n\u00ean b\u1eaft \u0111\u1ea7u v\u1edbi li\u1ec1u th\u1ea5p h\u01a1n li\u1ec1u ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh, v\u00e0 duy tr\u00ec \u1edf kho\u1ea3ng \u00bd \u2013 \u00be li\u1ec1u th\u00f4ng th\u01b0\u1eddng, t\u00f9y thu\u1ed9c ph\u1ea3n \u1ee9ng sinh h\u1ecdc.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p>D\u00f9ng nguy\u00ean vi\u00ean Tegrucil-4 b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng t\u1ea1i m\u1ed9t th\u1eddi \u0111i\u1ec3m nh\u1ea5t \u0111\u1ecbnh trong ng\u00e0y<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c Tegrucil-4 trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi acenocoumarol c\u00f3 trong Tegrucil-4 ho\u1eb7c c\u00e1c d\u1eabn ch\u1ea5t coumarin.<\/li>\n<li>B\u1ec7nh l\u00fd d\u1ec5 ch\u1ea3y m\u00e1u nh\u01b0 vi\u00eam n\u1ed9i t\u00e2m m\u1ea1c nhi\u1ec5m khu\u1ea9n, suy gan n\u1eb7ng, lo\u1ea1n s\u1ea3n m\u00e1u.<\/li>\n<li>T\u0103ng huy\u1ebft \u00e1p n\u1eb7ng, gi\u00e3n t\u0129nh m\u1ea1ch th\u1ef1c qu\u1ea3n, lo\u00e9t ti\u00eau h\u00f3a ti\u1ebfn tri\u1ec3n.<\/li>\n<li>Sau ph\u1eabu thu\u1eadt m\u1eaft ho\u1eb7c th\u1ea7n kinh, ho\u1eb7c chu\u1ea9n b\u1ecb ph\u1eabu thu\u1eadt c\u00f3 nguy c\u01a1 ch\u1ea3y m\u00e1u.<\/li>\n<li>Suy th\u1eadn n\u1eb7ng (ClCr &lt; 20 ml\/ph\u00fat).<\/li>\n<li>Ph\u1ee5 n\u1eef mang thai.<\/li>\n<li>Kh\u00f4ng d\u00f9ng trong v\u00f2ng 48 gi\u1edd sau sinh.<\/li>\n<li>Kh\u00f4ng k\u1ebft h\u1ee3p v\u1edbi aspirin li\u1ec1u cao, miconazol, phenylbutazon ho\u1eb7c c\u00e1c NSAID nh\u00f3m pyrazol.<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>Th\u00f4ng th\u01b0\u1eddng, c\u00f3 th\u1ec3 ng\u01b0ng thu\u1ed1c m\u00e0 kh\u00f4ng c\u1ea7n gi\u1ea3m li\u1ec1u d\u1ea7n. Tuy nhi\u00ean, \u1edf b\u1ec7nh nh\u00e2n c\u00f3 nguy c\u01a1 cao, vi\u1ec7c ng\u01b0ng \u0111\u1ed9t ng\u1ed9t c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 huy\u1ebft kh\u1ed1i.<\/li>\n<li>C\u1ea7n \u0111\u00e1nh gi\u00e1 kh\u1ea3 n\u0103ng tu\u00e2n th\u1ee7 \u0111i\u1ec1u tr\u1ecb c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh, \u0111\u1eb7c bi\u1ec7t l\u00e0 ng\u01b0\u1eddi cao tu\u1ed5i.<\/li>\n<li>Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng cho tr\u1ebb em do thi\u1ebfu d\u1eef li\u1ec7u l\u00e2m s\u00e0ng.<\/li>\n<li>Theo d\u00f5i INR \u0111\u1ecbnh k\u1ef3 t\u1ea1i c\u00f9ng m\u1ed9t ph\u00f2ng x\u00e9t nghi\u1ec7m \u0111\u1ec3 \u0111\u1ea3m b\u1ea3o \u0111\u1ed9 ch\u00ednh x\u00e1c.<\/li>\n<li>Th\u1eadn tr\u1ecdng \u1edf ng\u01b0\u1eddi suy gan, th\u1eadn, h\u1ea1 protein m\u00e1u.<\/li>\n<li>C\u1ea9n th\u1eadn trong v\u00e0i th\u00e1ng \u0111\u1ea7u v\u00ec nguy c\u01a1 xu\u1ea5t huy\u1ebft cao.<\/li>\n<li>Tr\u00e1nh d\u1eebng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t tr\u1eeb khi c\u00f3 ch\u1ec9 \u0111\u1ecbnh.<\/li>\n<li>Thu\u1ed1c ch\u1ee9a lactose \u2013 kh\u00f4ng d\u00f9ng cho b\u1ec7nh nh\u00e2n kh\u00f4ng dung n\u1ea1p galactose do di truy\u1ec1n.<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>T\u00e1c d\u1ee5ng ph\u1ee5 th\u01b0\u1eddng g\u1eb7p v\u00e0 \u0111\u00e1ng lo ng\u1ea1i nh\u1ea5t c\u1ee7a acenocoumarol l\u00e0 ch\u1ea3y m\u00e1u, c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf b\u1ea5t k\u1ef3 v\u1ecb tr\u00ed n\u00e0o trong c\u01a1 th\u1ec3. Nguy c\u01a1 n\u00e0y cao h\u01a1n trong nh\u1eefng tu\u1ea7n \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb, khi li\u1ec1u ch\u01b0a \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh \u1ed5n \u0111\u1ecbnh. M\u1ed9t s\u1ed1 bi\u1ec3u hi\u1ec7n c\u00f3 th\u1ec3 bao g\u1ed3m:<\/p>\n<ul>\n<li>Ch\u1ea3y m\u00e1u m\u0169i, n\u01b0\u1edbu r\u0103ng, ti\u1ec3u ra m\u00e1u, ph\u00e2n \u0111en ho\u1eb7c c\u00f3 m\u00e1u.<\/li>\n<li>Rong kinh ho\u1eb7c ch\u1ea3y m\u00e1u b\u1ea5t th\u01b0\u1eddng \u1edf ph\u1ee5 n\u1eef.<\/li>\n<li>Xu\u1ea5t huy\u1ebft n\u1ed9i t\u1ea1ng nghi\u00eam tr\u1ecdng (n\u00e3o, \u0111\u01b0\u1eddng ti\u00eau h\u00f3a\u2026) c\u00f3 th\u1ec3 \u0111e d\u1ecda t\u00ednh m\u1ea1ng.<\/li>\n<\/ul>\n<p>Ngo\u00e0i ra, ng\u01b0\u1eddi b\u1ec7nh c\u00f3 th\u1ec3 g\u1eb7p m\u1ed9t s\u1ed1 t\u00e1c d\u1ee5ng ph\u1ee5 \u00edt g\u1eb7p kh\u00e1c nh\u01b0:<\/p>\n<ul>\n<li>T\u1ed5n th\u01b0\u01a1ng gan (hi\u1ebfm)<\/li>\n<li>R\u1ee5ng t\u00f3c (hi\u1ebfm).<\/li>\n<li>Ho\u1ea1i t\u1eed da: l\u00e0 bi\u1ebfn ch\u1ee9ng nghi\u00eam tr\u1ecdng, tuy hi\u1ebfm g\u1eb7p<\/li>\n<li>Ho\u1ea1i t\u1eed m\u00f4 m\u1ec1m t\u1ea1i c\u00e1c v\u1ecb tr\u00ed kh\u00e1c nh\u01b0 v\u00fa, \u0111\u00f9i, m\u00f4ng (hi\u1ebfm).<\/li>\n<\/ul>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Acenocoumarol c\u00f3 t\u01b0\u01a1ng t\u00e1c v\u1edbi r\u1ea5t nhi\u1ec1u thu\u1ed1c. C\u1ea7n th\u1eadn tr\u1ecdng khi ph\u1ed1i h\u1ee3p v\u1edbi thu\u1ed1c kh\u00e1c, \u0111\u1eb7c bi\u1ec7t trong v\u00e0i ng\u00e0y \u0111\u1ea7u sau thay \u0111\u1ed5i ph\u00e1c \u0111\u1ed3. M\u1ed9t s\u1ed1 t\u01b0\u01a1ng t\u00e1c quan tr\u1ecdng g\u1ed3m:<\/li>\n<li>Aspirin li\u1ec1u cao: T\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u do \u1ee9c ch\u1ebf k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u v\u00e0 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 thu\u1ed1c t\u1ef1 do.<\/li>\n<li>Miconazol: L\u00e0m t\u0103ng \u0111\u1ed9c t\u00ednh v\u00e0 nguy c\u01a1 xu\u1ea5t huy\u1ebft do gi\u1ea3m chuy\u1ec3n h\u00f3a acenocoumarol.<\/li>\n<li>Phenylbutazon v\u00e0 c\u00e1c NSAID pyrazol: G\u00e2y t\u1ed5n th\u01b0\u01a1ng ni\u00eam m\u1ea1c ti\u00eau h\u00f3a v\u00e0 t\u0103ng nguy c\u01a1 ch\u1ea3y m\u00e1u.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Ph\u1ee5 n\u1eef mang thai: Kh\u00f4ng d\u00f9ng trong su\u1ed1t thai k\u1ef3 do nguy c\u01a1 d\u1ecb t\u1eadt (\u0111\u1eb7c bi\u1ec7t trong 3 th\u00e1ng \u0111\u1ea7u), s\u1ea3y thai ho\u1eb7c xu\u1ea5t huy\u1ebft b\u00e0o thai. Ph\u1ea3i \u00e1p d\u1ee5ng bi\u1ec7n ph\u00e1p tr\u00e1nh thai trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>Cho con b\u00fa: V\u00ec thu\u1ed1c c\u00f3 th\u1ec3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9, n\u00ean ng\u01b0ng cho b\u00fa n\u1ebfu kh\u00f4ng th\u1ec3 ng\u1eebng \u0111i\u1ec1u tr\u1ecb, ho\u1eb7c b\u1ed5 sung vitamin K h\u00e0ng ng\u00e0y cho tr\u1ebb n\u1ebfu v\u1eabn ti\u1ebfp t\u1ee5c cho b\u00fa.<\/p>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>D\u00f9 kh\u00f4ng ghi nh\u1eadn \u1ea3nh h\u01b0\u1edfng tr\u1ef1c ti\u1ebfp \u0111\u1ebfn kh\u1ea3 n\u0103ng l\u00e1i xe hay v\u1eadn h\u00e0nh m\u00e1y m\u00f3c, ng\u01b0\u1eddi d\u00f9ng n\u00ean th\u1eadn tr\u1ecdng v\u00ec nguy c\u01a1 ch\u1ea3y m\u00e1u n\u1ed9i v\u00e0 ngo\u1ea1i khoa khi b\u1ecb ch\u1ea5n th\u01b0\u01a1ng.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Vi\u1ec7c \u0111i\u1ec1u tr\u1ecb khi s\u1eed d\u1ee5ng qu\u00e1 \u0111\u01a1n gi\u1ea3n Tegrucil-4 ph\u1ee5 thu\u1ed9c v\u00e0o gi\u00e1 tr\u1ecb INR (T\u1ef7 l\u1ec7 chu\u1ea9n h\u00f3a qu\u1ed1c t\u1ebf) c\u0169ng nh\u01b0 t\u00ecnh tr\u1ea1ng m\u00e1u c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh.<\/p>\n<p>C\u1ea7n x\u1eed l\u00fd theo t\u1eebng m\u1ee9c \u0111\u1ed9 c\u1ee5 th\u1ec3 v\u00e0 ti\u1ebfn h\u00e0nh t\u1eebng b\u01b0\u1edbc nh\u1eb1m h\u1ea1n ch\u1ebf ch\u1ebf \u0111\u1ed9 c\u01a1 c\u1ea5u th\u00e0nh huy\u1ebft \u0111\u1ec3 \u0111i\u1ec1u ch\u1ec9nh qu\u00e1 nhanh. Nh\u01b0ng x\u1eed tr\u00ed qu\u00e1 li\u1ec1u n\u00e0y ph\u1ea3i c\u00f3 s\u1ef1 tham gia c\u1ee7a c\u00e1c nh\u00e2n vi\u00ean y t\u1ebf, tuy\u1ec7t \u0111\u1ed1i kh\u00f4ng t\u1ef1 m\u00ecnh x\u1eed tr\u00ed<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<ul>\n<li>Gi\u1eef Tegrucil-4 \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/li>\n<li>Kh\u00f4ng \u0111\u1ec3 Tegrucil-4 trong t\u1ea7m v\u1edbi tr\u1ebb em<\/li>\n<li>Kh\u00f4ng s\u1eed d\u1ee5ng Tegrucil-4 khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/li>\n<\/ul>\n<h2>Thu\u1ed1c Tegrucil-4 gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>Tegrucil-4 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c Tegrucil-4 c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p Tegrucil-4 t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi Tegrucil-4 nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/thuoc-acenocoumarol\/\">Thu\u1ed1c Acenocoumarol-VNP 4<\/a> c\u00f3 th\u00e0nh ph\u1ea7n l\u00e0 Acenocoumarol-VNP 4 v\u1edbi h\u00e0m l\u01b0\u1ee3ng 4mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n S.P.M, \u0111i\u1ec1u tr\u1ecb b\u1ec7nh l\u00fd tim m\u1ea1ch.<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/vincerol-4mg\/\">Vincerol 4mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n l\u00e0 Acenocoumarol-VNP 4 v\u1edbi h\u00e0m l\u01b0\u1ee3ng 4mg, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m V\u0129nh Ph\u00fac, \u0111i\u1ec1u tr\u1ecb b\u1ec7nh l\u00fd tim m\u1ea1ch.<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c Tegrucil-4 \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/drugbank.vn\/thuoc\/Tegrucil-4&amp;VD-25455-16\" rel=\"noopener\">t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 12 th\u00e1ng 6 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/drugbank.vn\/thuoc\/Tegrucil-4&amp;VD-25455-16\" rel=\"noopener\">https:\/\/drugbank.vn\/thuoc\/Tegrucil-4&amp;VD-25455-16<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Tegrucil-4 l\u00e0 thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u d\u1ea1ng \u0111\u01b0\u1eddng u\u1ed1ng, gi\u00fap ng\u0103n ng\u1eeba huy\u1ebft kh\u1ed1i t\u0129nh m\u1ea1ch v\u00e0 bi\u1ebfn ch\u1ee9ng tim m\u1ea1ch. D\u00f9ng theo ch\u1ec9 \u0111\u1ecbnh v\u00e0 theo d\u00f5i INR \u0111\u1ecbnh k\u1ef3.<\/p>\n","protected":false},"author":1,"featured_media":123050,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-123049","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/123049","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=123049"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/123050"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=123049"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=123049"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=123049"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}