{"id":122795,"date":"2025-06-10T17:54:36","date_gmt":"2025-06-10T10:54:36","guid":{"rendered":"https:\/\/vnras.com\/drug\/?post_type=product&#038;p=122795"},"modified":"2025-07-24T13:13:02","modified_gmt":"2025-07-24T06:13:02","slug":"triplixam-10mg-2-5mg-10mg","status":"publish","type":"product","link":"https:\/\/vnras.com\/drug\/triplixam-10mg-2-5mg-10mg\/","title":{"rendered":"TRIPLIXAM 10mg\/2.5mg\/10mg"},"content":{"rendered":"<p><strong>Trong b\u00e0i vi\u1ebft n\u00e0y, d\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng gi\u1edbi thi\u1ec7u \u0111\u1ebfn c\u00e1c b\u1ea1n thu\u1ed1c TRIPLIXAM 10mg\/2.5mg\/10mg \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Servier (Ireland) Industries Ltd c\u00f3 s\u1ed1 \u0111\u0103ng k\u00fd l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam l\u00e0 VN3-8-17<\/strong><\/p>\n<h2>TRIPLIXAM 10mg\/2.5mg\/10mg l\u00e0 thu\u1ed1c g\u00ec?<\/h2>\n<h3>Th\u00e0nh ph\u1ea7n<\/h3>\n<p>Trong m\u1ed7i <strong>vi\u00ean u\u1ed1ngTRIPLIXAM 10mg\/2.5mg\/10mg<\/strong> c\u00f3 ch\u1ee9a:<\/p>\n<p>Perindopril (d\u01b0\u1edbi d\u1ea1ng perindopril arginine 10mg) &#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.6,79mg<\/p>\n<p>Indapamide&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230; 2,5mg<\/p>\n<p>Amlodipine (d\u01b0\u1edbi d\u1ea1ng Amlodipine besilate) &#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.10mg<\/p>\n<p>D\u1ea1ng b\u00e0o ch\u1ebf: Vi\u00ean n\u00e9n bao phim<\/p>\n<h3>Tr\u00ecnh b\u00e0y<\/h3>\n<p>S\u0110K: VN3-8-17<\/p>\n<p>Quy c\u00e1ch \u0111\u00f3ng g\u00f3i: H\u1ed9p 1 l\u1ecd x 30 vi\u00ean<\/p>\n<p>Xu\u1ea5t x\u1ee9: Ireland<\/p>\n<p>H\u1ea1n s\u1eed d\u1ee5ng: 24 th\u00e1ng<\/p>\n<h2>T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c TRIPLIXAM 10mg\/2.5mg\/10mg<\/h2>\n<h3>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng<\/h3>\n<h4>Perindopril<\/h4>\n<p>Perindopril l\u00e0 thu\u1ed1c \u1ee9c ch\u1ebf enzym chuy\u1ec3n angiotensin (ACE), ng\u0103n c\u1ea3n qu\u00e1 tr\u00ecnh chuy\u1ec3n \u0111\u1ed5i angiotensin I th\u00e0nh angiotensin II \u2013 m\u1ed9t ch\u1ea5t g\u00e2y co m\u1ea1ch v\u00e0 k\u00edch th\u00edch tuy\u1ebfn th\u01b0\u1ee3ng th\u1eadn ti\u1ebft aldosteron. \u0110\u1ed3ng th\u1eddi, perindopril gi\u00fap duy tr\u00ec n\u1ed3ng \u0111\u1ed9 bradykinin \u2013 m\u1ed9t ch\u1ea5t g\u00e2y gi\u00e3n m\u1ea1ch \u2013 b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf s\u1ef1 ph\u00e2n h\u1ee7y c\u1ee7a n\u00f3. Nh\u1eefng thay \u0111\u1ed5i n\u00e0y d\u1eabn \u0111\u1ebfn gi\u1ea3m s\u1ee9c c\u1ea3n ngo\u1ea1i bi\u00ean, t\u0103ng ho\u1ea1t t\u00ednh renin huy\u1ebft t\u01b0\u01a1ng v\u00e0 gi\u1ea3m b\u00e0i ti\u1ebft aldosteron. Hi\u1ec7u qu\u1ea3 h\u1ea1 huy\u1ebft \u00e1p \u0111\u01b0\u1ee3c ghi nh\u1eadn \u1edf c\u1ea3 b\u1ec7nh nh\u00e2n c\u00f3 n\u1ed3ng \u0111\u1ed9 renin b\u00ecnh th\u01b0\u1eddng ho\u1eb7c th\u1ea5p.<\/p>\n<p>Ho\u1ea1t t\u00ednh c\u1ee7a perindopril ch\u1ee7 y\u1ebfu th\u00f4ng qua ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh l\u00e0 perindoprilat. Thu\u1ed1c c\u00f3 kh\u1ea3 n\u0103ng l\u00e0m gi\u00e3n m\u1ea1ch, c\u1ea3i thi\u1ec7n \u0111\u00e0n h\u1ed3i \u0111\u1ed9ng m\u1ea1ch, gi\u1ea3m ph\u00ec \u0111\u1ea1i th\u1ea5t tr\u00e1i v\u00e0 c\u1ea3i thi\u1ec7n huy\u1ebft \u0111\u1ed9ng h\u1ecdc \u1edf b\u1ec7nh nh\u00e2n suy tim. Khi d\u00f9ng l\u00e2u d\u00e0i, thu\u1ed1c kh\u00f4ng g\u00e2y gi\u1eef n\u01b0\u1edbc hay nh\u1ecbp tim nhanh ph\u1ea3n x\u1ea1, kh\u00f4ng g\u00e2y hi\u1ec7n t\u01b0\u1ee3ng t\u0103ng huy\u1ebft \u00e1p tr\u1edf l\u1ea1i khi ng\u1eebng thu\u1ed1c.<\/p>\n<h4>Indapamid<\/h4>\n<p>Indapamid l\u00e0 m\u1ed9t d\u1eabn xu\u1ea5t sulfonamid thu\u1ed9c nh\u00f3m thu\u1ed1c l\u1ee3i ti\u1ec3u t\u01b0\u01a1ng t\u1ef1 thiazid, c\u00f3 kh\u1ea3 n\u0103ng \u1ee9c ch\u1ebf t\u00e1i h\u1ea5p thu natri t\u1ea1i ph\u1ea7n v\u1ecf c\u1ee7a \u1ed1ng l\u01b0\u1ee3n xa. Thu\u1ed1c l\u00e0m t\u0103ng b\u00e0i ti\u1ebft natri, clorid, kali v\u00e0 magie, t\u1eeb \u0111\u00f3 th\u00fac \u0111\u1ea9y th\u1ea3i n\u01b0\u1edbc ti\u1ec3u v\u00e0 h\u1ea1 huy\u1ebft \u00e1p. Indapamid c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m s\u1ee9c c\u1ea3n m\u1ea1ch m\u00e1u nh\u1ecf v\u00e0 c\u1ea3i thi\u1ec7n t\u00ednh \u0111\u00e0n h\u1ed3i \u0111\u1ed9ng m\u1ea1ch, g\u00f3p ph\u1ea7n v\u00e0o hi\u1ec7u qu\u1ea3 h\u1ea1 \u00e1p k\u00e9o d\u00e0i trong 24 gi\u1edd d\u00f9 li\u1ec1u d\u00f9ng c\u00f3 t\u00ednh l\u1ee3i ti\u1ec3u t\u1ed1i thi\u1ec3u. Thu\u1ed1c c\u0169ng \u0111\u01b0\u1ee3c ch\u1ee9ng minh kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u00e1ng k\u1ec3 \u0111\u1ebfn chuy\u1ec3n h\u00f3a lipid ho\u1eb7c glucose, ngay c\u1ea3 \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng.<\/p>\n<h4>Amlodipin<\/h4>\n<p>Amlodipin l\u00e0 thu\u1ed1c ch\u1eb9n k\u00eanh calci nh\u00f3m dihydropyridin, \u1ee9c ch\u1ebf d\u00f2ng calci \u0111i v\u00e0o t\u1ebf b\u00e0o c\u01a1 tr\u01a1n m\u1ea1ch m\u00e1u v\u00e0 c\u01a1 tim. T\u00e1c d\u1ee5ng h\u1ea1 \u00e1p ch\u00ednh l\u00e0 do gi\u00e3n m\u1ea1ch ngo\u1ea1i bi\u00ean, t\u1eeb \u0111\u00f3 gi\u1ea3m h\u1eadu g\u00e1nh v\u00e0 ti\u00eau th\u1ee5 oxy c\u1ee7a c\u01a1 tim. Ngo\u00e0i ra, thu\u1ed1c c\u0169ng gi\u00e3n c\u00e1c \u0111\u1ed9ng m\u1ea1ch v\u00e0nh v\u00e0 ti\u1ec3u \u0111\u1ed9ng m\u1ea1ch, t\u0103ng cung c\u1ea5p m\u00e1u cho v\u00f9ng c\u01a1 tim thi\u1ebfu m\u00e1u. Amlodipin c\u00f3 th\u1eddi gian t\u00e1c d\u1ee5ng k\u00e9o d\u00e0i, h\u1ea1 huy\u1ebft \u00e1p \u1ed5n \u0111\u1ecbnh trong 24 gi\u1edd, kh\u00f4ng g\u00e2y t\u1ee5t \u00e1p \u0111\u1ed9t ng\u1ed9t v\u00e0 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn chuy\u1ec3n h\u00f3a lipid ho\u1eb7c glucose, ph\u00f9 h\u1ee3p cho b\u1ec7nh nh\u00e2n c\u00f3 k\u00e8m \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, hen ho\u1eb7c gout.<\/p>\n<h4>Ph\u1ed1i h\u1ee3p Perindopril\/Indapamid<\/h4>\n<p>S\u1ef1 k\u1ebft h\u1ee3p gi\u1eefa perindopril v\u00e0 indapamid t\u1ea1o ra hi\u1ec7u \u1ee9ng c\u1ed9ng h\u1ee3p trong vi\u1ec7c h\u1ea1 huy\u1ebft \u00e1p, l\u00e0m t\u0103ng hi\u1ec7u l\u1ef1c \u0111i\u1ec1u tr\u1ecb so v\u1edbi d\u00f9ng t\u1eebng thu\u1ed1c \u0111\u01a1n l\u1ebb. \u0110\u1ed3ng th\u1eddi, ph\u1ed1i h\u1ee3p n\u00e0y gi\u00fap gi\u1ea3m nguy c\u01a1 h\u1ea1 kali m\u00e1u do l\u1ee3i ti\u1ec3u, c\u1ea3i thi\u1ec7n ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p m\u00e0 kh\u00f4ng l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng ph\u1ee5.<\/p>\n<p>\u0110\u1eb7c \u0111i\u1ec3m d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc<\/p>\n<p>Perindopril<\/p>\n<p>Sau khi u\u1ed1ng perindopril, ho\u1ea1t ch\u1ea5t n\u00e0y nhanh ch\u00f3ng \u0111\u01b0\u1ee3c h\u1ea5p thu v\u00e0 \u0111\u1ea1t Cmax sau kho\u1ea3ng 1h. Thu\u1ed1c l\u00e0 ti\u1ec1n ch\u1ea5t v\u00e0 chuy\u1ec3n h\u00f3a th\u00e0nh perindoprilat \u2013 ch\u1ea5t c\u00f3 ho\u1ea1t t\u00ednh \u2013 v\u1edbi n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 3\u20134 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi th\u1ee9c \u0103n n\u00ean n\u00ean d\u00f9ng v\u00e0o bu\u1ed5i s\u00e1ng tr\u01b0\u1edbc \u0103n.<\/p>\n<p>Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 c\u1ee7a perindoprilat kho\u1ea3ng 0,2 L\/kg, t\u1ef7 l\u1ec7 g\u1eafn k\u1ebft protein kho\u1ea3ng 20%, ph\u1ee5 thu\u1ed9c li\u1ec1u. Kho\u1ea3ng 27% li\u1ec1u u\u1ed1ng chuy\u1ec3n th\u00e0nh perindoprilat. Perindoprilat th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u, th\u1eddi gian b\u00e1n th\u1ea3i kho\u1ea3ng 17 gi\u1edd, \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh sau 4 ng\u00e0y. D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc tuy\u1ebfn t\u00ednh theo li\u1ec1u d\u00f9ng.<\/p>\n<p>\u1ede ng\u01b0\u1eddi cao tu\u1ed5i ho\u1eb7c b\u1ec7nh nh\u00e2n suy th\u1eadn, kh\u1ea3 n\u0103ng th\u1ea3i tr\u1eeb gi\u1ea3m n\u00ean c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u. \u1ede b\u1ec7nh nh\u00e2n x\u01a1 gan, chuy\u1ec3n h\u00f3a thu\u1ed1c m\u1eb9 gi\u1ea3m nh\u01b0ng l\u01b0\u1ee3ng perindoprilat kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng, kh\u00f4ng c\u1ea7n hi\u1ec7u ch\u1ec9nh li\u1ec1u.<\/p>\n<p>Indapamid<\/p>\n<p>Indapamid h\u1ea5p thu t\u1ed1t qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a trong huy\u1ebft t\u01b0\u01a1ng sau kho\u1ea3ng 1 gi\u1edd. Thu\u1ed1c li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 79%. Thu\u1ed1c chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu qua gan v\u00e0 th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u v\u00e0 ph\u00e2n. T\u00e1c d\u1ee5ng k\u00e9o d\u00e0i \u0111\u1ee7 \u0111\u1ec3 d\u00f9ng m\u1ed7i ng\u00e0y m\u1ed9t l\u1ea7n. \u1ede li\u1ec1u \u0111i\u1ec1u tr\u1ecb, indapamid c\u00f3 t\u00e1c d\u1ee5ng l\u1ee3i ti\u1ec3u nh\u1eb9 v\u00e0 hi\u1ec7u qu\u1ea3 h\u1ea1 \u00e1p \u1ed5n \u0111\u1ecbnh.<\/p>\n<p>Amlodipin<\/p>\n<p>Amlodipin \u0111\u01b0\u1ee3c h\u1ea5p thu ch\u1eadm qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t sau 6\u201312 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng kho\u1ea3ng 60\u201380%, kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi th\u1ee9c \u0103n. Thu\u1ed1c ph\u00e2n b\u1ed1 r\u1ed9ng v\u00e0 g\u1eafn k\u1ebft protein kho\u1ea3ng 93\u201398%.<\/p>\n<p>Chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu t\u1ea1i gan th\u00e0nh c\u00e1c ch\u1ea5t kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh v\u00e0 th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u. Th\u1eddi gian b\u00e1n th\u1ea3i k\u00e9o d\u00e0i t\u1eeb 35\u201350 gi\u1edd, cho ph\u00e9p d\u00f9ng m\u1ed7i ng\u00e0y m\u1ed9t l\u1ea7n. \u1ede ng\u01b0\u1eddi cao tu\u1ed5i ho\u1eb7c suy gan, th\u1eddi gian b\u00e1n th\u1ea3i k\u00e9o d\u00e0i h\u01a1n, n\u00ean c\u00e2n nh\u1eafc \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u n\u1ebfu c\u1ea7n.<\/p>\n<p>Ph\u1ed1i h\u1ee3p Perindopril\/Indapamid\/Amlodipin (TRIPLIXAM)<\/p>\n<p>Khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi perindopril, indapamid v\u00e0 amlodipin, kh\u00f4ng ghi nh\u1eadn s\u1ef1 thay \u0111\u1ed5i \u0111\u00e1ng k\u1ec3 v\u1ec1 d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a t\u1eebng th\u00e0nh ph\u1ea7n so v\u1edbi khi d\u00f9ng \u0111\u01a1n \u0111\u1ed9c. Do \u0111\u00f3, c\u00e1c thu\u1ed1c n\u00e0y c\u00f3 th\u1ec3 ph\u1ed1i h\u1ee3p trong m\u1ed9t vi\u00ean m\u00e0 kh\u00f4ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn hi\u1ec7u qu\u1ea3 hay an to\u00e0n c\u1ee7a t\u1eebng ho\u1ea1t ch\u1ea5t.<\/p>\n<h2>Thu\u1ed1c TRIPLIXAM 10mg\/2.5mg\/10mg \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh trong b\u1ec7nh g\u00ec?<\/h2>\n<p>TRIPLIXAM \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh thay th\u1ebf cho b\u1ec7nh nh\u00e2n t\u0103ng huy\u1ebft \u00e1p \u0111\u00e3 \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t huy\u1ebft \u00e1p b\u1eb1ng c\u00e1c th\u00e0nh ph\u1ea7n ri\u00eang l\u1ebb g\u1ed3m perindopril\/indapamid v\u00e0 amlodipin v\u1edbi li\u1ec1u t\u01b0\u01a1ng \u1ee9ng.<\/p>\n<figure id=\"attachment_122806\" aria-describedby=\"caption-attachment-122806\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-122806\" src=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/TRIPLIXAM-10mg2.5mg10mg.jpg\" alt=\"TRIPLIXAM 10mg\/2.5mg\/10mg\" width=\"1200\" height=\"800\" title=\"\" srcset=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/TRIPLIXAM-10mg2.5mg10mg.jpg 1200w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/TRIPLIXAM-10mg2.5mg10mg-600x400.jpg 600w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/TRIPLIXAM-10mg2.5mg10mg-768x512.jpg 768w, https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/TRIPLIXAM-10mg2.5mg10mg-350x233.jpg 350w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-122806\" class=\"wp-caption-text\">Thu\u1ed1c TRIPLIXAM 10mg\/2.5mg\/10mg ch\u1ee9a 3 ho\u1ea1t ch\u1ea5t Perindopril, Indapamide, Amlodipine ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p \u1edf ng\u01b0\u1eddi c\u00f3 \u0111\u00e1p \u1ee9ng v\u1edbi c\u00e1c th\u00e0nh ph\u1ea7n ri\u00eang l\u1ebb n\u00e0y tr\u01b0\u1edbc \u0111\u00f3<\/figcaption><\/figure>\n<h2>Li\u1ec1u d\u00f9ng v\u00e0 c\u00e1ch s\u1eed d\u1ee5ng<\/h2>\n<h3>Li\u1ec1u d\u00f9ng<\/h3>\n<p>Li\u1ec1u th\u00f4ng th\u01b0\u1eddng: 1 vi\u00ean m\u1ed7i ng\u00e0y, u\u1ed1ng v\u00e0o bu\u1ed5i s\u00e1ng tr\u01b0\u1edbc b\u1eefa \u0103n.<\/p>\n<p>Kh\u00f4ng s\u1eed d\u1ee5ng ph\u1ed1i h\u1ee3p li\u1ec1u c\u1ed1 \u0111\u1ecbnh cho \u0111i\u1ec1u tr\u1ecb kh\u1edfi \u0111\u1ea7u.<\/p>\n<p>N\u00ean \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u v\u1edbi t\u1eebng th\u00e0nh ph\u1ea7n ri\u00eang bi\u1ec7t khi c\u1ea7n.<\/p>\n<h3>C\u00e1ch s\u1eed d\u1ee5ng<\/h3>\n<p><strong>Vi\u00ean n\u00e9n TRIPLIXAM 10mg\/2.5mg\/10mg<\/strong> \u0111\u01b0\u1ee3c d\u00f9ng b\u1eb1ng \u0111\u01b0\u1eddng u\u1ed1ng<\/p>\n<h3>\u0110\u1ed1i t\u01b0\u1ee3ng \u0111\u1eb7c bi\u1ec7t<\/h3>\n<p>Suy th\u1eadn:<\/p>\n<ul>\n<li>N\u1eb7ng (&lt;30 ml\/ph\u00fat): Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh.<\/li>\n<li>V\u1eeba (30\u201360 ml\/ph\u00fat): Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh v\u1edbi d\u1ea1ng 10mg\/2.5mg\/5mg.<\/li>\n<li>N\u00ean \u0111i\u1ec1u tr\u1ecb b\u1eb1ng c\u00e1c th\u00e0nh ph\u1ea7n r\u1eddi v\u00e0 theo d\u00f5i creatinin, kali th\u01b0\u1eddng xuy\u00ean.<\/li>\n<li>Kh\u00f4ng ph\u1ed1i h\u1ee3p perindopril v\u1edbi aliskiren \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn c\u00f3 GFR &lt;60 ml\/ph\u00fat\/1,73 m\u00b2.<\/li>\n<\/ul>\n<p>Suy gan:<\/p>\n<ul>\n<li>N\u1eb7ng: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh.<\/li>\n<li>Nh\u1eb9 \u0111\u1ebfn v\u1eeba: Th\u1eadn tr\u1ecdng khi d\u00f9ng do ch\u01b0a c\u00f3 li\u1ec1u khuy\u1ebfn c\u00e1o r\u00f5 r\u00e0ng cho amlodipin.<\/li>\n<\/ul>\n<p>Ng\u01b0\u1eddi cao tu\u1ed5i: C\u00f3 th\u1ec3 d\u00f9ng t\u00f9y theo ch\u1ee9c n\u0103ng th\u1eadn do \u0111\u1ed9 thanh th\u1ea3i perindoprilat gi\u1ea3m.<\/p>\n<p>Tr\u1ebb em v\u00e0 thanh thi\u1ebfu ni\u00ean: Ch\u01b0a x\u00e1c l\u1eadp t\u00ednh an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3.<\/p>\n<h2>Kh\u00f4ng s\u1eed d\u1ee5ng thu\u1ed1c TRIPLIXAM 10mg\/2.5mg\/10mg trong tr\u01b0\u1eddng h\u1ee3p n\u00e0o?<\/h2>\n<ul>\n<li>Ng\u01b0\u1eddi d\u1ecb \u1ee9ng v\u1edbi ho\u1ea1t ch\u1ea5t c\u00f3 trong TRIPLIXAM ho\u1eb7c v\u1edbi sulfonamid, dihydropyridine, ACEI.<\/li>\n<li>Suy th\u1eadn n\u1eb7ng ho\u1eb7c v\u1eeba (t\u00f9y d\u1ea1ng thu\u1ed1c).<\/li>\n<li>Suy tim m\u1ea5t b\u00f9 ch\u01b0a \u0111i\u1ec1u tr\u1ecb.<\/li>\n<li>Ti\u1ec1n s\u1eed ho\u1eb7c di truy\u1ec1n ph\u00f9 m\u1ea1ch.<\/li>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai (giai \u0111o\u1ea1n 2 &amp; 3), cho con b\u00fa.<\/li>\n<li>B\u1ec7nh n\u00e3o gan, suy gan n\u1eb7ng.<\/li>\n<li>H\u1ea1 kali m\u00e1u, h\u1ea1 huy\u1ebft \u00e1p n\u1eb7ng, s\u1ed1c (bao g\u1ed3m s\u1ed1c tim).<\/li>\n<li>H\u1eb9p van \u0111\u1ed9ng m\u1ea1ch ch\u1ee7, suy tim huy\u1ebft \u0111\u1ed9ng kh\u00f4ng \u1ed5n \u0111\u1ecbnh sau nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p.<\/li>\n<li>D\u00f9ng \u0111\u1ed3ng th\u1eddi aliskiren \u1edf ng\u01b0\u1eddi ti\u1ec3u \u0111\u01b0\u1eddng ho\u1eb7c suy th\u1eadn (GFR &lt;60 ml\/ph\u00fat\/1,73 m\u00b2).<\/li>\n<\/ul>\n<h2>L\u01b0u \u00fd \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c<\/h2>\n<h3>Th\u1eadn tr\u1ecdng<\/h3>\n<ul>\n<li>C\u1ea7n \u0111o m\u1ee9c \u0111\u1ed9 l\u1ecdc c\u1ea7u th\u1eadn \u0111\u1ec3 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u tr\u00ean b\u1ec7nh nh\u00e2n khi d\u00f9ng thu\u1ed1c<\/li>\n<li>C\u1ea7n theo d\u00f5i huy\u1ebft \u00e1p, kali, canxi, acid uric,&#8230; khi d\u00f9ng TRIPLIXAM<\/li>\n<li>C\u1ea7n ch\u00fa \u00fd theo d\u00f5i n\u1ebfu d\u00f9ng TRIPLIXAM v\u1edbi b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng, suy tim, suy gan, ng\u01b0\u1eddi cao tu\u1ed5i<\/li>\n<\/ul>\n<h3>T\u00e1c d\u1ee5ng ph\u1ee5<\/h3>\n<p>D\u1eef li\u1ec7u an to\u00e0n ghi nh\u1eadn c\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i ph\u1ed5 bi\u1ebfn nh\u1ea5t c\u1ee7a t\u1eebng th\u00e0nh ph\u1ea7n ri\u00eang l\u1ebb trong TRIPLIXAM g\u1ed3m: ch\u00f3ng m\u1eb7t, \u0111au \u0111\u1ea7u, d\u1ecb c\u1ea3m, m\u1ea5t th\u0103ng b\u1eb1ng, bu\u1ed3n ng\u1ee7, nh\u00ecn m\u1edd, \u00f9 tai, \u0111\u1ecf b\u1eebng m\u1eb7t, \u0111\u00e1nh tr\u1ed1ng ng\u1ef1c, h\u1ea1 huy\u1ebft \u00e1p v\u00e0 c\u00e1c bi\u1ec3u hi\u1ec7n li\u00ean quan, ho, kh\u00f3 th\u1edf, r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a (\u0111au b\u1ee5ng, bu\u1ed3n n\u00f4n, n\u00f4n, t\u00e1o b\u00f3n, ti\u00eau ch\u1ea3y, r\u1ed1i lo\u1ea1n v\u1ecb gi\u00e1c, kh\u00f3 ti\u00eau), ng\u1ee9a, ph\u00e1t ban, m\u1ea9n \u0111\u1ecf, chu\u1ed9t r\u00fat, ph\u00f9 m\u1eaft c\u00e1 ch\u00e2n, m\u1ec7t m\u1ecfi, suy nh\u01b0\u1ee3c v\u00e0 ph\u00f9 ngo\u1ea1i vi.<\/p>\n<h3>T\u01b0\u01a1ng t\u00e1c<\/h3>\n<ul>\n<li>Phong b\u1ebf k\u00e9p h\u1ec7 RAA: T\u0103ng nguy c\u01a1 h\u1ea1 huy\u1ebft \u00e1p, t\u0103ng kali m\u00e1u, suy th\u1eadn c\u1ea5p.<\/li>\n<li>Thu\u1ed1c l\u00e0m t\u0103ng kali m\u00e1u: aliskiren, mu\u1ed1i kali, thu\u1ed1c gi\u1eef kali, NSAID, heparin, ciclosporin, trimethoprim&#8230;<\/li>\n<li>Ph\u1ed1i h\u1ee3p ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh: aliskiren \u1edf b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng ho\u1eb7c suy th\u1eadn.<\/li>\n<li>Chi ti\u1ebft c\u00e1c thu\u1ed1c kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng ho\u1eb7c c\u1ea7n th\u1eadn tr\u1ecdng xem trong t\u1edd h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa<\/h3>\n<p>Mang thai: Kh\u00f4ng khuy\u1ebfn c\u00e1o \u1edf 3 th\u00e1ng \u0111\u1ea7u. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh t\u1eeb tam c\u00e1 nguy\u1ec7t th\u1ee9 2 tr\u1edf \u0111i.<\/p>\n<p>Cho con b\u00fa: Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng TRIPLIXAM.<\/p>\n<ul>\n<li>Perindopril: Kh\u00f4ng c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u \u2192 kh\u00f4ng khuy\u1ebfn c\u00e1o.<\/li>\n<li>Indapamid: C\u00f3 th\u1ec3 gi\u1ea3m ho\u1eb7c ng\u1eebng ti\u1ebft s\u1eefa \u2192 kh\u00f4ng khuy\u1ebfn c\u00e1o.<\/li>\n<li>Amlodipin: Ch\u01b0a r\u00f5 c\u00f3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 hay kh\u00f4ng.<\/li>\n<\/ul>\n<h3>L\u01b0u \u00fd khi s\u1eed d\u1ee5ng cho ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c<\/h3>\n<p>Amlodipin c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng nh\u1eb9 \u0111\u1ebfn v\u1eeba \u2192 c\u1ea7n th\u1eadn tr\u1ecdng khi kh\u1edfi tr\u1ecb n\u1ebfu c\u00f3 ch\u00f3ng m\u1eb7t, m\u1ec7t m\u1ecfi,&#8230;<\/p>\n<p>Perindopril v\u00e0 indapamid \u00edt \u1ea3nh h\u01b0\u1edfng, nh\u01b0ng c\u00f3 th\u1ec3 g\u00e2y h\u1ea1 huy\u1ebft \u00e1p \u1edf m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n.<\/p>\n<h3>Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed<\/h3>\n<p>Hi\u1ec7n ch\u01b0a c\u00f3 d\u1eef li\u1ec7u v\u1ec1 qu\u00e1 li\u1ec1u TRIPLIXAM tr\u00ean ng\u01b0\u1eddi.<\/p>\n<p>V\u1edbi ph\u1ed1i h\u1ee3p perindopril\/indapamid: qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 g\u00e2y h\u1ea1 huy\u1ebft \u00e1p, bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, l\u00fa l\u1eabn, bu\u1ed3n ng\u1ee7, thi\u1ec3u ni\u1ec7u ho\u1eb7c v\u00f4 ni\u1ec7u do gi\u1ea3m th\u1ec3 t\u00edch, c\u00f9ng v\u1edbi r\u1ed1i lo\u1ea1n \u0111i\u1ec7n gi\u1ea3i. X\u1eed tr\u00ed ch\u1ee7 y\u1ebfu l\u00e0 r\u1eeda d\u1ea1 d\u00e0y, than ho\u1ea1t, b\u00f9 d\u1ecbch v\u00e0 \u0111i\u1ec7n gi\u1ea3i t\u1ea1i c\u01a1 s\u1edf y t\u1ebf. C\u00f3 th\u1ec3 truy\u1ec1n d\u1ecbch ho\u1eb7c d\u00f9ng thu\u1ed1c t\u0103ng th\u1ec3 t\u00edch n\u1ebfu h\u1ea1 huy\u1ebft \u00e1p. Perindoprilat c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf qua l\u1ecdc m\u00e1u.<\/p>\n<p>V\u1edbi amlodipin: qu\u00e1 li\u1ec1u c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn gi\u00e3n m\u1ea1ch qu\u00e1 m\u1ee9c, t\u1ee5t huy\u1ebft \u00e1p k\u00e9o d\u00e0i, hi\u1ebfm khi g\u00e2y s\u1ed1c v\u00e0 t\u1eed vong. C\u1ea7n h\u1ed7 tr\u1ee3 tim m\u1ea1ch t\u00edch c\u1ef1c, theo d\u00f5i huy\u1ebft \u00e1p, nh\u1ecbp tim, n\u00e2ng cao ch\u00e2n v\u00e0 \u0111\u1ea3m b\u1ea3o l\u01b0\u1ee3ng d\u1ecbch tu\u1ea7n ho\u00e0n. C\u00f3 th\u1ec3 d\u00f9ng thu\u1ed1c co m\u1ea1ch v\u00e0 ti\u00eam calci gluconat t\u0129nh m\u1ea1ch n\u1ebfu c\u1ea7n. Than ho\u1ea1t c\u00f3 hi\u1ec7u qu\u1ea3 n\u1ebfu d\u00f9ng s\u1edbm, nh\u01b0ng ch\u1ea1y th\u1eadn kh\u00f4ng gi\u00fap \u00edch do amlodipin g\u1eafn m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng.<\/p>\n<h3>B\u1ea3o qu\u1ea3n<\/h3>\n<ul>\n<li>Gi\u1eef TRIPLIXAM 10mg\/2.5mg\/10mg \u1edf n\u01a1i kh\u00f4 r\u00e1o, tho\u00e1ng m\u00e1t (&lt;30\u2103), tr\u00e1nh \u00e1nh n\u1eafng qu\u00e1 m\u1ea1nh t\u1eeb m\u1eb7t tr\u1eddi<\/li>\n<li>Kh\u00f4ng \u0111\u1ec3 TRIPLIXAM 10mg\/2.5mg\/10mg trong t\u1ea7m v\u1edbi tr\u1ebb em<\/li>\n<li>Kh\u00f4ng s\u1eed d\u1ee5ng TRIPLIXAM 10mg\/2.5mg\/10mg khi qu\u00e1 h\u1ea1n cho ph\u00e9p<\/li>\n<\/ul>\n<h2>Thu\u1ed1c TRIPLIXAM 10mg\/2.5mg\/10mg gi\u00e1 bao nhi\u00eau? b\u00e1n \u1edf \u0111\u00e2u?<\/h2>\n<p>TRIPLIXAM 10mg\/2.5mg\/10mg hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c b\u00e1n t\u1ea1i Nh\u00e0 thu\u1ed1c D\u01b0\u1ee3c s\u0129 L\u01b0u V\u0103n Ho\u00e0ng, gi\u00e1 thu\u1ed1c TRIPLIXAM 10mg\/2.5mg\/10mg c\u00f3 th\u1ec3 \u0111\u00e3 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadp t\u1ea1i \u0111\u1ea7u trang. Hi\u1ec7n nay, nh\u00e0 thu\u1ed1c ch\u00fang t\u00f4i h\u1ed7 tr\u1ee3 giao h\u00e0ng to\u00e0n qu\u1ed1c. Qu\u00fd kh\u00e1ch h\u00e0ng c\u00f3 th\u1ec3 li\u00ean h\u1ec7 qua s\u1ed1 hotline \u0111\u1ec3 \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n k\u1ecbp th\u1eddi.<\/p>\n<p>Tr\u01b0\u1eddng h\u1ee3p TRIPLIXAM 10mg\/2.5mg\/10mg t\u1ea1m th\u1eddi h\u1ebft h\u00e0ng, qu\u00fd kh\u00e1ch c\u00f3 th\u1ec3 tham kh\u1ea3o c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a nh\u00e0 thu\u1ed1c c\u00f3 c\u00f9ng ho\u1ea1t ch\u1ea5t v\u00e0 t\u00e1c d\u1ee5ng v\u1edbi TRIPLIXAM 10mg\/2.5mg\/10mg nh\u01b0:<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/triplixam-10mg-2-5mg-5mg\/\">TRIPLIXAM 10mg\/2.5mg\/5mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n l\u00e0 Perindopril, Indapamide v\u00e0 Amlodipine, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Servier (Ireland) Industries Ltd, \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p<\/p>\n<p><a href=\"https:\/\/vnras.com\/drug\/triplixam-5mg-1-25mg-5mg\/\">Triplixam 5mg\/1.25mg\/5mg<\/a> c\u00f3 th\u00e0nh ph\u1ea7n l\u00e0 Perindopril, Indapamide v\u00e0 Amlodipine, \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1edfi Servier (Ireland) Industries Ltd, \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p<\/p>\n<h2>T\u00e0i li\u1ec7u tham kh\u1ea3o<\/h2>\n<p>T\u1edd H\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng thu\u1ed1c TRIPLIXAM 10mg\/2.5mg\/10mg \u0111\u01b0\u1ee3c B\u1ed9 Y t\u1ebf ph\u00ea duy\u1ec7t. Xem v\u00e0 t\u1ea3i v\u1ec1 b\u1ea3n PDF \u0111\u1ea7y \u0111\u1ee7 <a href=\"https:\/\/vnras.com\/drug\/wp-content\/uploads\/2025\/06\/To-huong-dan-su-dung-triplixam-10mg-2.5mg-10mg.pdf\">t\u1ea1i \u0111\u00e2y<\/a>. Truy c\u1eadp ng\u00e0y 4 th\u00e1ng 6 n\u0103m 2025 t\u1eeb: <a href=\"https:\/\/drugbank.vn\/thuoc\/TRIPLIXAM-10mg-2-5mg-10mg&amp;VN3-8-17\" rel=\"noopener\">https:\/\/drugbank.vn\/thuoc\/TRIPLIXAM-10mg-2-5mg-10mg&amp;VN3-8-17<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p><span style=\"font-weight: 400;\">Thu\u1ed1c TRIPLIXAM 10mg\/2.5mg\/10mg ch\u1ee9a 3 ho\u1ea1t ch\u1ea5t <\/span><span style=\"font-weight: 400;\">Perindopril, Indapamide, Amlodipine ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p \u1edf ng\u01b0\u1eddi c\u00f3 \u0111\u00e1p \u1ee9ng v\u1edbi c\u00e1c th\u00e0nh ph\u1ea7n ri\u00eang l\u1ebb n\u00e0y tr\u01b0\u1edbc \u0111\u00f3<\/span><\/p>\n","protected":false},"author":1,"featured_media":122797,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_cat":[89],"product_tag":[],"class_list":{"0":"post-122795","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-thuoc","8":"first","9":"instock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product\/122795","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/types\/product"}],"author":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/comments?post=122795"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media\/122797"}],"wp:attachment":[{"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/media?parent=122795"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_cat?post=122795"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/vnras.com\/drug\/wp-json\/wp\/v2\/product_tag?post=122795"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}